@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0738: (2017-12-28 )
MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRELVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAE
Atome Classification :
(30 SA)
.........10........20........30......-..40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......-170.......180.......190.......200.......210...-....220.......230....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
S
I
H
I
A
AQQGEIA
D
K
ILLPGD
P
L
R
A
K
F
I
A
E
N
FLG
D
A
V
-
C
F
N
E
V
R
N
M
FGYTGTYKG
H
R
V
S
V
M
GTGMGMP
S
I
S
I
Y
A
R
E
L
I
V
D
Y
G
V
K
K
L
I
RVGTAGSLNE
E
V
H
V
R
E
L
V
L
A
Q
AAATNSNIVRNDWPQYDFPQ
I
A
S
F
D
L
L
D
K
A
Y
H
I
A
K
E
LGMT
T
H
V
G
N
V
L
S
S
D
V
F
Y
S
N
Y
F
E
KNIE-LGKWG
V
K
A
V
E
M
E
A
A
A
L
Y
Y
L
A
A
QYH
V
D
A
L
A
I
M
T
I
S
D
SLVNPDEDT
T
A
-
E
E
R
Q
N
T
F
T
D
M
M
K
V
G
L
E
T
LIAE
1
PsiBlast_PDB
95.00
80%
-120
- C1 -
-
4TYM
-
?
A:
[24-258]
-
S
I
H
I
E
A
K
Q
G
E
I
A
D
K
I
L
L
P
G
D
P
L
R
A
K
F
I
A
E
N
F
L
E
D
A
V
-
C
F
N
T
V
R
N
M
F
G
Y
T
G
T
Y
K
G
H
R
V
S
V
M
G
T
G
M
G
M
P
S
I
S
I
Y
A
R
E
L
I
V
D
Y
G
V
K
T
L
I
R
V
G
T
A
G
A
I
N
P
D
I
H
V
R
E
L
V
L
A
Q
A
A
A
T
N
S
N
I
I
R
N
D
W
P
E
F
D
F
P
Q
I
A
D
F
K
L
L
D
K
A
Y
H
I
A
K
E
M
D
I
T
T
H
V
G
S
V
L
S
S
D
V
F
Y
S
N
Q
P
D
R
N
M
A
-
L
G
K
L
G
V
H
A
I
E
M
E
A
A
A
L
Y
Y
L
A
A
Q
H
N
V
N
A
L
A
M
M
T
I
S
D
N
L
N
N
P
E
E
D
T
S
A
-
E
E
R
Q
T
T
F
T
D
M
M
K
V
G
L
E
T
L
I
S
E
146
HHSearch
84.74
82%
-52
- C1 -
-
4TYM
-
?
A:
[24-258]
-
S
I
H
I
E
A
K
Q
G
E
I
A
D
K
I
L
L
P
G
D
P
L
R
A
K
F
I
A
E
N
F
-
L
E
D
A
V
C
F
N
T
V
R
N
M
F
G
Y
T
G
T
Y
K
G
H
R
V
S
V
M
G
T
G
M
G
M
P
S
I
S
I
Y
A
R
E
L
I
V
D
Y
G
V
K
T
L
I
R
V
G
T
A
G
A
I
N
P
D
I
H
V
R
E
L
V
L
A
Q
A
A
A
T
N
S
N
I
I
R
N
D
W
P
E
F
D
F
P
Q
I
A
D
F
K
L
L
D
K
A
Y
H
I
A
K
E
M
D
I
T
T
H
V
G
S
V
L
S
S
D
V
F
Y
S
N
Q
P
D
R
N
M
A
-
L
G
K
L
G
V
H
A
I
E
M
E
A
A
A
L
Y
Y
L
A
A
Q
H
N
V
N
A
L
A
M
M
T
I
S
D
N
L
N
N
P
E
-
E
D
T
S
A
E
E
R
Q
T
T
F
T
D
M
M
K
V
G
L
E
T
L
I
S
E
4
PsiBlast_PDB
84.68
55%
-120
- C1 -
-
3UAY
3
DEOD_BACCE
A:
[2-234]
-
S
V
H
I
E
A
K
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
V
T
-
C
Y
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
G
V
K
N
L
I
R
V
G
T
C
G
A
I
Q
K
D
V
K
V
R
D
V
I
I
A
M
T
A
C
T
D
S
N
M
N
R
L
T
F
P
G
F
D
F
A
P
A
A
N
F
D
L
L
K
K
A
Y
D
A
G
T
E
K
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
E
S
M
D
M
V
K
K
-
L
G
D
Y
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
N
H
I
F
T
-
G
E
E
T
T
S
-
E
E
R
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
I
Q
-
38
PsiBlast_CBE
84.02
52%
-105
- C1 -
-
4D8V
1
DEOD_BACSU
B:
[22-251]
-
S
V
H
I
G
A
E
K
G
Q
I
A
D
T
V
L
L
P
G
D
P
L
R
A
K
F
I
A
E
T
Y
L
E
N
V
E
-
C
Y
N
E
V
R
G
M
Y
G
F
T
G
T
Y
K
G
K
K
I
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
D
V
Q
N
L
I
R
V
G
S
C
G
A
I
R
K
D
V
K
V
R
D
V
I
L
A
M
T
S
S
T
D
S
Q
M
N
R
V
A
F
G
S
V
D
F
A
P
C
A
D
F
E
L
L
K
N
A
Y
D
A
A
K
D
K
G
V
P
V
T
V
G
S
V
F
T
A
D
Q
F
Y
N
D
--
D
S
Q
I
E
K
L
A
K
Y
G
V
L
G
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
H
G
R
K
A
L
S
I
L
T
V
S
D
H
V
L
T
-
G
E
E
T
T
A
-
E
E
R
Q
T
T
F
H
D
M
I
D
V
A
L
H
S
V
---
133
PsiBlast_CBE
83.97
50%
-132
- C1 -
-
1PR1
1
DEOD_ECO57
B:
[5-234]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
8
PsiBlast_PDB
83.94
55%
-126
- C1 -
-
4MAR
-
?
A:
[26-254]
---
H
I
S
A
P
P
G
A
V
A
E
A
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
E
N
P
V
-
L
Y
N
Q
V
R
N
M
F
G
Y
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
I
P
S
A
S
I
Y
I
H
E
L
V
Q
F
Y
G
C
K
T
L
I
R
V
G
T
A
G
A
I
T
E
R
L
K
L
R
D
L
V
I
A
Q
A
A
C
T
D
S
S
I
N
N
L
R
F
A
G
Q
N
Y
A
P
I
A
T
F
D
L
L
R
R
A
Y
E
Q
A
Q
S
R
G
M
P
V
H
V
G
N
V
L
S
T
D
T
F
Y
H
D
Q
P
N
P
Y
Q
L
-
W
A
Q
F
G
V
L
A
V
E
M
E
A
A
G
L
Y
T
L
A
A
K
F
G
V
Q
A
L
C
I
L
T
I
S
D
H
L
I
T
-
G
E
K
T
T
P
-
Q
E
R
Q
E
T
F
D
Q
M
I
E
V
A
L
E
T
I
---
5
PsiBlast_PDB
83.72
55%
-119
- C1 -
-
3UAZ
3
DEOD_BACCE
A:
[2-234]
-
S
V
H
I
E
A
K
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
V
T
-
C
Y
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
G
V
K
N
L
I
R
V
G
T
C
G
A
I
Q
K
D
V
K
V
R
D
V
I
I
A
M
T
A
C
T
D
S
N
M
N
R
L
T
F
P
G
F
D
F
A
P
A
A
N
F
D
L
L
K
K
A
Y
D
A
G
T
E
K
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
E
S
M
D
M
V
K
K
-
L
G
D
Y
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
N
H
I
F
T
-
G
E
E
T
T
S
-
E
E
R
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
I
Q
-
98
PsiBlast_CBE
83.43
50%
-128
- C1 -
-
1PK9
1
DEOD_ECO57
A:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
95
PsiBlast_CBE
83.25
50%
-127
- C1 -
-
1PKE
1
DEOD_ECO57
A:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
41
PsiBlast_CBE
83.24
51%
-126
- C1 -
-
1VHW
2
DEOD1_VIBCH
D:
[7-236]
---
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
N
A
V
-
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
-
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
-
I
K
T
G
E
Q
T
T
S
-
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
S
V
L
--
33
PsiBlast_CBE
83.06
52%
-100
- C1 -
-
4D8Y
2
DEOD_BACSU
F:
[21-251]
M
S
V
H
I
G
A
E
K
G
Q
I
A
D
T
V
L
L
P
G
D
P
L
R
A
K
F
I
A
E
T
Y
L
E
N
V
E
-
C
Y
N
E
V
R
G
M
Y
G
F
T
G
T
Y
K
G
K
K
I
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
D
V
Q
N
L
I
R
V
G
S
C
G
A
I
R
K
D
V
K
V
R
D
V
I
L
A
M
T
S
S
T
D
S
Q
M
N
R
V
A
F
G
S
V
D
F
A
P
C
A
D
F
E
L
L
K
N
A
Y
D
A
A
K
D
K
G
V
P
V
T
V
G
S
V
F
T
A
D
Q
F
Y
N
D
--
D
S
Q
I
E
K
L
A
K
Y
G
V
L
G
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
H
G
R
K
A
L
S
I
L
T
V
S
D
H
V
L
T
-
G
E
E
T
T
A
-
E
E
R
Q
T
T
F
H
D
M
I
D
V
A
L
H
S
V
---
37
PsiBlast_CBE
82.99
52%
-102
- C1 -
-
4D8Y
3
DEOD_BACSU
B:
[21-251]
M
S
V
H
I
G
A
E
K
G
Q
I
A
D
T
V
L
L
P
G
D
P
L
R
A
K
F
I
A
E
T
Y
L
E
N
V
E
-
C
Y
N
E
V
R
G
M
Y
G
F
T
G
T
Y
K
G
K
K
I
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
D
V
Q
N
L
I
R
V
G
S
C
G
A
I
R
K
D
V
K
V
R
D
V
I
L
A
M
T
S
S
T
D
S
Q
M
N
R
V
A
F
G
S
V
D
F
A
P
C
A
D
F
E
L
L
K
N
A
Y
D
A
A
K
D
K
G
V
P
V
T
V
G
S
V
F
T
A
D
Q
F
Y
N
D
--
D
S
Q
I
E
K
L
A
K
Y
G
V
L
G
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
H
G
R
K
A
L
S
I
L
T
V
S
D
H
V
L
T
-
G
E
E
T
T
A
-
E
E
R
Q
T
T
F
H
D
M
I
D
V
A
L
H
S
V
---
3
PsiBlast_PDB
82.95
56%
-118
- C1 -
-
3UAW
3
DEOD_BACCE
A:
[2-234]
-
S
V
H
I
E
A
K
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
V
T
-
C
Y
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
G
V
K
N
L
I
R
V
G
T
C
G
A
I
Q
K
D
V
K
V
R
D
V
I
I
A
M
T
A
C
T
D
S
N
M
N
R
L
T
F
P
G
F
D
F
A
P
A
A
N
F
D
L
L
K
K
A
Y
D
A
G
T
E
K
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
E
S
M
D
M
V
K
K
-
L
G
D
Y
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
D
H
I
F
T
-
G
E
E
T
T
S
-
E
E
R
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
I
Q
-
63
PsiBlast_CBE
82.90
50%
-126
- C1 -
-
3UT6
2
DEOD_ECOLI
C:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
34
PsiBlast_CBE
82.87
52%
-100
- C1 -
-
4D8Y
3
DEOD_BACSU
E:
[21-251]
M
S
V
H
I
G
A
E
K
G
Q
I
A
D
T
V
L
L
P
G
D
P
L
R
A
K
F
I
A
E
T
Y
L
E
N
V
E
-
C
Y
N
E
V
R
G
M
Y
G
F
T
G
T
Y
K
G
K
K
I
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
D
V
Q
N
L
I
R
V
G
S
C
G
A
I
R
K
D
V
K
V
R
D
V
I
L
A
M
T
S
S
T
D
S
Q
M
N
R
V
A
F
G
S
V
D
F
A
P
C
A
D
F
E
L
L
K
N
A
Y
D
A
A
K
D
K
G
V
P
V
T
V
G
S
V
F
T
A
D
Q
F
Y
N
D
--
D
S
Q
I
E
K
L
A
K
Y
G
V
L
G
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
H
G
R
K
A
L
S
I
L
T
V
S
D
H
V
L
T
-
G
E
E
T
T
A
-
E
E
R
Q
T
T
F
H
D
M
I
D
V
A
L
H
S
V
---
44
PsiBlast_CBE
82.71
51%
-126
- C1 -
-
1VHW
2
DEOD1_VIBCH
A:
[7-236]
---
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
N
A
V
-
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
-
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
-
I
K
T
G
E
Q
T
T
S
-
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
S
V
L
--
127
PsiBlast_CBE
82.64
50%
-123
- C1 -
-
1PR4
1
DEOD_ECO57
B:
[5-234]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
60
PsiBlast_CBE
82.63
50%
-124
- C1 -
-
4RJ2
1
?
C:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
43
PsiBlast_CBE
82.61
51%
-123
- C1 -
-
1VHW
2
DEOD1_VIBCH
B:
[7-236]
---
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
N
A
V
-
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
-
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
-
I
K
T
G
E
Q
T
T
S
-
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
S
V
L
--
59
PsiBlast_CBE
82.53
50%
-123
- C1 -
-
4RJ2
4
?
D:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
21
PsiBlast_CBE
82.18
56%
-129
- C1 -
-
2AC7
2
DEOD_BACAN
B:
[2-232]
-
S
V
H
I
E
A
K
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
V
T
-
C
Y
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
G
V
K
N
L
I
R
V
G
T
C
G
A
I
Q
K
D
V
K
V
R
D
V
I
I
A
M
T
A
C
T
D
S
N
M
N
R
L
T
F
P
G
F
D
F
A
P
A
A
N
F
D
L
L
K
K
A
Y
D
A
G
T
E
K
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
E
S
M
D
M
V
K
K
-
L
G
D
Y
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
D
H
I
F
------------
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
---
96
PsiBlast_CBE
81.68
50%
-121
- C1 -
-
1PK9
1
DEOD_ECO57
C:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
2
PsiBlast_PDB
79.99
56%
-131
- C1 -
-
2AC7
2
DEOD_BACAN
A:
[2-232]
-
S
V
H
I
E
A
K
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
V
T
-
C
Y
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
G
V
K
N
L
I
R
V
G
T
C
G
A
I
Q
K
D
V
K
V
R
D
V
I
I
A
M
T
A
C
T
D
S
N
M
N
R
L
T
F
P
G
F
D
F
A
P
A
A
N
F
D
L
L
K
K
A
Y
D
A
G
T
E
K
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
E
S
M
D
M
V
K
K
-
L
G
D
Y
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
D
H
I
-------------
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
---
116
PsiBlast_CBE
79.64
50%
-125
- C1 -
-
1A69
2
DEOD_ECOLI
A:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
48
PsiBlast_CBE
79.58
50%
-124
- C1 -
-
5I3C
1
DEOD_ECOLI
C:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
134
PsiBlast_CBE
79.30
50%
-131
- C1 -
-
1PR1
1
DEOD_ECO57
A:
[5-234]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-------------
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
101
PsiBlast_CBE
79.27
50%
-130
- C1 -
-
1PK7
1
DEOD_ECO57
A:
[4-233]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--
18
PsiBlast_PDB
78.65
52%
-99
- C1 -
-
4DAB
3
DEOD_BACSU
A:
[22-251]
-
S
V
H
I
G
A
E
K
G
Q
I
A
D
T
V
L
L
P
G
D
P
L
R
A
K
F
I
A
E
T
Y
L
E
N
V
E
-
C
Y
N
E
V
R
G
M
Y
G
F
T
G
T
Y
K
G
K
K
I
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
D
V
Q
N
L
I
R
V
G
S
C
G
A
I
R
K
D
V
K
V
R
D
V
I
L
A
M
T
S
S
T
D
S
Q
M
N
R
V
A
F
G
S
V
D
F
A
P
C
A
D
F
E
L
L
K
N
A
Y
D
A
A
K
D
K
G
V
P
V
T
V
G
S
V
F
T
A
D
Q
F
Y
N
D
--
D
S
Q
I
E
K
L
A
K
Y
G
V
L
G
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
H
G
R
K
A
L
S
I
L
T
V
S
D
H
V
L
T
-
G
E
E
T
T
A
-
E
E
R
Q
T
T
F
H
D
M
I
D
V
A
L
H
S
V
---
28
PsiBlast_CBE
77.77
52%
-99
- C1 -
-
4DAO
2
DEOD_BACSU
B:
[22-251]
-
S
V
H
I
G
A
E
K
G
Q
I
A
D
T
V
L
L
P
G
D
P
L
R
A
K
F
I
A
E
T
Y
L
E
N
V
E
-
C
Y
N
E
V
R
G
M
Y
G
F
T
G
T
Y
K
G
K
K
I
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
D
V
Q
N
L
I
R
V
G
S
C
G
A
I
R
K
D
V
K
V
R
D
V
I
L
A
M
T
S
S
T
D
S
Q
M
N
R
V
A
F
G
S
V
D
F
A
P
C
A
D
F
E
L
L
K
N
A
Y
D
A
A
K
D
K
G
V
P
V
T
V
G
S
V
F
T
A
D
Q
F
Y
N
D
--
D
S
Q
I
E
K
L
A
K
Y
G
V
L
G
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
H
G
R
K
A
L
S
I
L
T
V
S
D
H
V
L
T
-
G
E
E
T
T
A
-
E
E
R
Q
T
T
F
H
D
M
I
D
V
A
L
H
S
V
---
123
PsiBlast_CBE
77.75
50%
-117
- C1 -
-
1PR5
1
DEOD_ECO57
C:
[5-234]
---
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
D
A
R
-
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
V
N
R
I
R
F
K
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
-
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
-
I
R
T
H
E
Q
T
T
A
-
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
--