@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0906: (2018-01-01 )
MVKELFMKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKLSEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSILAEELK
Atome Classification :
(20 SA)
.........10........20........30......-..40........50........60..-.-.....70........80........90.......----.100.......-110-.........120....-...130.......140.-......150.......160.......170.......180.......190.......200-.--.--......210.......220.......230.......240.......250.......260.......270.....---..280--.---....--...290--...--......300.......310
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
V
K
E
L
F
M
K
K
Q
N
L
F
L
V
L
L
S
V
F
L
L
C
L
GACGQKESQTGKG-
M
K
I
V
T
S
F
Y
P
I
Y
A
M
V
K
E
VSGDLN
D
V
R
M
-I-QSSSGIHSFEPSAN
D
I
A
A
I
Y
D
A
D
V
F
V
Y
HSH
T
L
E
S
----
W
AGSLDPNLKK-S---
K
V
K
V
L
EASEG
M
T
L
ERV-PGLEDVEAGDGVDEKTL-YDPHTWL
D
P
E
KAG
E
E
A
Q
I
I
A
D
K
L
S
E
V
D
S
E
H
K
E
T
Y
Q
K
N
A
Q
A
F
I
K
K
A
Q
E
L
T
K
K
F
Q
P
K
F
E
K
--
A
--
T
--
Q
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
RFG
L
N
QLGIAGISPEQEPS
P
R
Q
L
T
E
I
Q
E
F
V
K
TY
K
V
K
T
I
F
TESNA
S
S
K
V
A
E
T
L
V
K
STGV---G
L
K
T---L---NPLE--SDPQ----N
D
K
--
T
Y
L
E
N
L
E
E
N
M
S
I
L
A
E
ELK
1
PsiBlast_PDB
92.95
98%
-73
- C4 -
-
3CX3
-
?
A:
[7-283]
---------------------------------
T
G
K
G
-
M
K
I
V
T
S
F
Y
P
I
Y
A
M
V
K
E
V
S
G
D
L
N
D
V
R
M
-
I
-
Q
S
S
S
G
I
H
S
F
E
P
S
A
N
D
I
A
A
I
Y
D
A
D
V
F
V
Y
H
S
H
T
L
E
S
----
W
A
G
S
L
D
P
N
L
K
K
-
S
---
K
V
K
V
L
E
A
S
E
G
M
T
L
E
R
V
-
P
G
-------------
T
L
-
Y
D
P
H
T
W
L
D
P
E
K
A
G
E
E
A
Q
I
I
A
D
K
L
S
E
V
D
S
E
H
K
E
T
Y
Q
K
N
A
Q
A
F
I
K
K
A
Q
E
L
T
K
K
F
Q
P
K
F
E
K
--
A
--
T
--
Q
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
N
Q
L
G
I
A
G
I
S
P
E
Q
E
P
S
P
R
Q
L
T
E
I
Q
E
F
V
K
T
Y
K
V
K
T
I
F
T
E
S
N
A
S
S
K
V
A
E
T
L
V
K
S
T
G
V
---
G
L
K
T
---
L
---
N
P
L
E
--
S
D
P
Q
----
N
D
K
--
T
Y
L
E
N
L
E
E
N
M
S
I
L
A
E
E
L
-
43
HHSearch
91.81
100%
-81
- C4 -
-
3CX3
-
?
B:
[9-284]
-----------------------------------
K
G
-
M
K
I
V
T
S
F
Y
P
I
Y
A
M
V
K
E
V
S
G
D
L
N
D
V
R
M
-
I
-
Q
S
S
S
G
I
H
S
F
E
P
S
A
N
D
I
A
A
I
Y
D
A
D
V
F
V
Y
H
S
H
T
L
E
S
----
W
A
G
S
L
D
P
N
L
K
K
-
S
---
K
V
K
V
L
E
A
S
E
G
M
T
L
E
R
V
-
P
G
-------------
T
L
-
Y
D
P
H
T
W
L
D
P
E
K
A
G
E
E
A
Q
I
I
A
D
K
L
S
E
V
D
S
E
H
K
E
T
Y
Q
K
N
A
Q
A
F
I
K
K
A
Q
E
L
T
K
K
F
Q
P
K
F
E
K
--
A
--
T
--
Q
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
N
Q
L
G
I
A
G
I
S
P
E
Q
E
P
S
P
R
Q
L
T
E
I
Q
E
F
V
K
T
Y
K
V
K
T
I
F
T
E
S
N
A
S
--
V
A
E
T
L
V
K
S
T
G
V
---
G
L
K
T
---
L
---
N
P
L
E
--
S
D
P
-----
N
D
K
--
T
Y
L
E
N
L
E
E
N
M
S
I
L
A
E
E
L
K
2
PsiBlast_PDB
83.99
66%
-85
- C4 -
-
3GI1
-
?
A:
[10-286]
----------------------------------
T
Q
G
-
M
S
V
V
T
S
F
Y
P
M
Y
A
M
T
K
E
V
S
G
D
L
N
D
V
R
M
-
I
------
I
H
S
F
E
P
S
V
N
D
V
A
A
I
Y
D
A
D
L
F
V
Y
H
S
H
T
L
E
A
----
W
A
R
D
L
D
P
N
L
K
K
-
S
---
K
V
D
V
F
E
A
S
K
P
L
T
L
D
R
V
-
K
---------------
L
-
Y
D
P
H
T
W
T
D
P
V
L
A
G
E
E
A
V
N
I
A
K
E
L
G
R
L
D
P
K
H
K
D
S
Y
T
K
N
A
K
A
F
K
K
E
A
E
Q
L
T
E
E
Y
T
Q
K
F
K
K
--
V
--
R
--
S
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
K
Q
L
G
I
S
G
I
S
P
---
P
S
P
R
Q
L
K
E
I
Q
D
F
V
K
E
Y
N
V
K
T
I
F
A
E
D
N
V
N
P
K
I
A
H
A
I
A
K
S
T
G
A
---
K
V
K
T
---
L
---
S
P
L
E
--
A
A
P
S
----
G
N
K
--
T
Y
L
E
N
L
R
A
N
L
E
V
L
Y
Q
Q
L
K
3
PsiBlast_PDB
82.98
67%
-70
- C4 -
-
3HJT
-
?
A:
[12-287]
-----------------------------------
Q
G
-
M
S
V
V
T
S
F
Y
P
M
Y
A
M
T
K
E
V
S
G
D
L
N
D
V
R
M
-
I
-
Q
S
G
A
G
I
H
S
F
E
P
S
V
N
D
V
A
A
I
Y
D
A
D
L
F
V
Y
H
S
H
T
L
E
A
----
W
A
R
D
L
D
P
---
K
-
S
---
K
V
N
V
F
E
A
S
K
P
L
T
L
D
R
V
-
K
G
-------------
T
L
-
Y
D
P
H
T
W
T
D
P
V
L
A
G
E
E
A
V
N
I
A
K
E
L
G
H
L
D
P
K
H
K
D
S
Y
T
K
K
A
K
A
F
K
K
E
A
E
Q
L
T
E
E
Y
T
Q
K
F
K
K
--
V
--
R
--
S
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
K
Q
L
G
I
S
G
I
S
P
E
Q
E
P
S
P
R
Q
L
K
E
I
Q
D
F
V
K
E
Y
N
V
K
T
I
F
A
E
D
N
V
N
P
K
I
A
H
A
I
A
K
S
T
G
A
---
K
V
K
T
---
L
---
S
P
L
E
--
A
A
P
S
----
G
N
K
--
T
Y
L
E
N
L
R
A
N
L
E
V
L
Y
Q
Q
L
K
47
HHSearch
82.49
66%
-73
- C4 -
-
4H0F
-
?
A:
[1-264]
------------------------------------
G
-
M
S
V
V
T
S
F
Y
P
M
Y
A
M
T
K
E
V
S
G
D
L
N
D
V
R
M
-
I
-
Q
S
G
A
G
I
H
S
F
E
P
S
V
N
D
V
A
A
I
Y
D
A
D
L
F
V
Y
H
S
H
T
L
E
A
----
W
A
R
D
L
D
P
N
L
K
K
-
S
---
K
V
N
V
F
E
A
S
K
P
L
T
--
L
D
----------
R
V
K
P
G
A
T
V
-
Y
D
P
H
T
W
T
D
P
V
L
A
G
E
E
A
V
N
I
A
K
E
L
G
H
L
D
P
K
H
K
D
S
Y
T
K
K
A
K
A
F
K
K
E
A
E
Q
L
T
E
E
Y
T
Q
K
F
K
K
--
V
--
R
--
S
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
K
Q
L
G
I
S
G
I
S
P
E
Q
E
P
S
P
R
Q
L
K
E
I
Q
D
F
V
K
E
Y
N
V
K
T
I
F
A
E
D
N
V
N
P
K
I
A
H
A
I
A
K
S
T
G
A
---
K
V
K
T
---
L
---
S
P
L
E
--
A
A
P
S
----
G
N
K
--
T
Y
L
E
N
L
R
A
N
L
E
V
L
Y
Q
Q
L
K
4
PsiBlast_PDB
78.49
65%
18
- C4 -
-
4H0F
-
?
A:
[1-264]
------------------------------------
G
-
M
S
V
V
T
S
F
Y
P
M
Y
A
M
T
K
E
V
S
G
D
L
N
D
V
R
M
-
I
-
Q
S
G
A
G
I
H
S
F
E
P
S
V
N
D
V
A
A
I
Y
D
A
D
L
F
V
Y
H
S
H
T
L
E
A
----
W
A
R
D
L
D
P
N
L
K
K
-
S
---
K
V
N
V
F
E
A
S
K
P
L
T
L
D
R
V
K
P
G
------------
A
T
V
-
Y
D
P
H
T
W
T
D
P
V
L
A
G
E
E
A
V
N
I
A
K
E
L
G
H
L
D
P
K
H
K
D
S
Y
T
K
K
A
K
A
F
K
K
E
A
E
Q
L
T
E
E
Y
T
Q
K
F
K
K
--
V
--
R
--
S
K
T
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
K
Q
L
G
I
S
G
I
S
P
E
Q
E
P
S
P
R
Q
L
K
E
I
Q
D
F
V
K
E
Y
N
V
K
T
I
F
A
E
D
N
V
N
P
K
I
A
H
A
I
A
K
S
T
G
A
---
K
V
K
T
---
L
---
S
P
L
E
--
A
A
P
S
----
G
N
K
--
T
Y
L
E
N
L
R
A
N
L
E
V
L
Y
Q
Q
L
K
48
HHSearch
66.35
38%
35
- C4 -
-
2O1E
-
ZNUA_BACSU
A:
[21-301]
------------------------------------
K
-
L
H
V
V
T
T
F
Y
P
M
Y
E
F
T
K
Q
I
V
K
D
K
G
D
V
D
L
L
I
-
P
S
S
V
E
P
H
D
W
E
P
T
P
K
D
I
A
N
I
Q
D
A
D
L
F
V
Y
N
S
E
Y
M
E
T
----
W
V
P
S
A
E
K
S
M
G
Q
-
G
---
H
A
V
F
V
N
A
S
K
G
I
D
L
M
E
G
----------------
H
A
-
M
D
P
H
V
W
L
S
P
V
L
A
Q
K
E
V
K
N
I
T
A
Q
I
V
K
Q
D
P
D
N
K
E
Y
Y
E
K
N
S
K
E
Y
I
A
K
L
Q
D
L
D
K
L
Y
R
T
T
A
K
K
--
A
--
E
--
K
K
E
F
I
T
Q
H
T
A
F
G
Y
L
A
K
E
Y
G
L
K
Q
V
P
I
A
G
L
S
P
D
Q
E
P
S
A
A
S
L
A
K
L
K
T
Y
A
K
E
H
N
V
K
V
I
Y
F
E
E
I
A
S
S
K
V
A
D
T
L
A
S
E
I
G
A
---
K
T
E
V
---
L
---
N
T
L
E
--
G
L
S
K
E
E
Q
D
K
G
L
--
G
Y
I
D
I
M
K
Q
N
L
D
A
L
K
D
S
L
L
5
PsiBlast_PDB
65.21
39%
58
- C4 -
-
2O1E
-
ZNUA_BACSU
A:
[21-300]
-------------------------------------K
L
H
V
V
T
T
F
Y
P
M
Y
E
F
T
K
Q
I
V
K
D
K
G
D
V
D
L
L
I
-
P
S
S
V
E
P
H
D
W
E
P
T
P
K
D
I
A
N
I
Q
D
A
D
L
F
V
Y
N
S
E
Y
M
E
T
----
W
V
P
S
A
E
K
S
M
G
Q
-
G
---
H
A
V
F
V
N
A
S
K
G
I
D
L
M
E
G
-----------------
H
A
M
D
P
H
V
W
L
S
P
V
L
A
Q
K
E
V
K
N
I
T
A
Q
I
V
K
Q
D
P
D
N
K
E
Y
Y
E
K
N
S
K
E
Y
I
A
K
L
Q
D
L
D
K
L
Y
R
T
T
A
K
K
--
A
--
E
--
K
K
E
F
I
T
Q
H
T
A
F
G
Y
L
A
K
E
Y
G
L
K
Q
V
P
I
A
G
L
S
P
D
Q
E
P
S
A
A
S
L
A
K
L
K
T
Y
A
K
E
H
N
V
K
V
I
Y
F
E
E
I
A
S
S
K
V
A
D
T
L
A
S
E
I
G
A
---
K
T
E
V
---
L
---
N
T
L
E
GL
S
K
E
E
----
Q
D
K
GL
G
Y
I
D
I
M
K
Q
N
L
D
A
L
K
D
S
L
-
12
PsiBlast_PDB
64.79
28%
24
- C4 -
-
5UYB
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
20
PsiBlast_PDB
64.45
28%
18
- C4 -
-
5UYW
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
15
PsiBlast_PDB
64.41
28%
26
- C4 -
-
5UYE
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
16
PsiBlast_PDB
64.37
28%
25
- C4 -
-
5UYF
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
11
PsiBlast_PDB
64.28
28%
24
- C4 -
-
5UYA
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
13
PsiBlast_PDB
64.23
28%
25
- C4 -
-
5UYC
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
6
PsiBlast_PDB
64.07
28%
24
- C4 -
-
5UXS
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
19
PsiBlast_PDB
64.00
28%
26
- C4 -
-
5UYV
-
?
A:
[38-302]
---------------------------------
T
A
K
K
-
F
K
V
V
T
T
F
T
I
I
Q
D
I
A
Q
N
I
A
G
D
V
A
V
V
E
S
-
I
T
K
P
G
A
E
I
H
D
Y
Q
P
T
P
R
D
I
V
K
A
Q
S
A
D
L
I
L
W
N
G
M
N
L
E
R
----
W
F
E
K
F
F
E
S
I
K
D
-
V
---
P
S
A
V
V
T
A
--
G
I
T
--
P
L
-
P
I
R
E
G
P
Y
S
G
-------
I
-
A
N
P
H
A
W
M
S
P
S
N
A
L
I
Y
I
E
N
I
R
K
A
L
V
E
H
D
P
A
H
A
E
T
Y
N
R
N
A
Q
A
Y
A
E
K
I
K
A
L
D
A
P
L
R
E
R
L
S
R
IP
A
--
E
--
Q
R
W
L
V
T
S
E
G
A
F
S
Y
L
A
K
D
Y
G
F
K
E
V
Y
L
W
P
I
N
A
E
Q
Q
G
I
P
Q
Q
V
R
H
V
I
D
I
I
R
E
N
K
I
P
V
V
F
S
E
S
T
I
S
D
K
P
A
K
Q
V
S
K
E
T
G
A
QYG
G
V
L
Y
---
V
---
D
S
L
S
--
G
E
K
G
----
P
V
P
--
T
Y
I
S
L
I
--
N
M
T
V
------
53
HHSearch
63.95
28%
26
- C4 -
-
5JPD
-
MNTA_LISMO
A:
[11-289]
-----------------------------------
G
K
-
L
N
V
V
A
T
Y
S
I
L
A
D
I
V
K
N
V
G
G
N
K
I
E
L
H
S
I
V
-
P
V
G
V
D
P
H
E
Y
D
P
L
P
A
N
I
Q
S
A
A
D
A
D
L
I
F
Y
N
G
L
N
L
E
T
GNG-
W
F
D
R
M
L
E
T
A
D
K
-
S
RED
K
N
Q
V
V
E
L
S
K
G
V
K
--
P
K
-
Y
-------
L
T
E
K
G
K
T
S
E
-
T
D
P
H
A
W
L
D
L
H
N
G
I
I
Y
T
E
N
V
R
D
A
L
V
K
A
D
P
D
N
A
D
F
Y
K
E
N
A
K
K
Y
I
D
K
L
A
T
L
D
K
E
A
K
Q
K
F
A
D
--
L
--
P
EN
Q
K
T
L
V
T
S
E
G
A
F
K
Y
F
A
A
R
Y
G
L
K
A
A
Y
I
W
E
I
N
T
E
S
Q
G
T
P
D
Q
M
K
Q
I
V
G
I
V
E
K
E
K
V
P
N
L
F
V
E
T
S
V
D
P
R
S
M
E
S
V
S
K
E
T
G
V
---
P
I
F
A
K
I
F
T
---
D
S
T
A
--
K
K
G
E
----
V
G
D
--
T
Y
L
E
M
M
R
Y
N
L
D
K
I
H
D
G
L
A
54
HHSearch
63.92
28%
26
- C4 -
-
5I4K
-
MNTA_LISMO
A:
[11-289]
-----------------------------------
G
K
-
L
N
V
V
A
T
Y
S
I
L
A
D
I
V
K
N
V
G
G
N
K
I
E
L
H
S
I
V
-
P
V
G
V
D
P
H
E
Y
D
P
L
P
A
N
I
Q
S
A
A
D
A
D
L
I
F
Y
N
G
L
N
L
E
T
GNG-
W
F
D
R
M
L
E
T
A
D
K
-
S
RED
K
N
Q
V
V
E
L
S
K
G
V
K
--
P
K
-
Y
-------
L
T
E
K
G
K
T
S
E
-
T
D
P
H
A
W
L
D
L
H
N
G
I
I
Y
T
E
N
V
R
D
A
L
V
K
A
D
P
D
N
A
D
F
Y
K
E
N
A
K
K
Y
I
D
K
L
A
T
L
D
K
E
A
K
Q
K
F
A
D
--
L
--
P
EN
Q
K
T
L
V
T
S
E
G
A
F
K
Y
F
A
A
R
Y
G
L
K
A
A
Y
I
W
E
I
N
T
E
S
Q
G
T
P
D
Q
M
K
Q
I
V
G
I
V
E
K
E
K
V
P
N
L
F
V
E
T
S
V
D
P
R
S
M
E
S
V
S
K
E
T
G
V
---
P
I
F
A
K
I
F
T
---
D
S
T
A
--
K
K
G
E
----
V
G
D
--
T
Y
L
E
M
M
R
Y
N
L
D
K
I
H
D
G
L
A
52
HHSearch
63.88
29%
62
- C4 -
-
3ZK7
3
MTSA_STRPN
A:
[1-277]
------------------------------------
K
-
L
K
V
V
A
T
N
S
I
I
A
D
I
T
K
N
I
A
G
D
K
I
D
L
H
S
I
V
-
P
I
G
Q
D
P
H
E
Y
E
P
L
P
E
D
V
K
K
T
S
E
A
D
L
I
F
Y
N
G
I
N
L
E
T
GGNA
W
F
T
K
L
V
E
N
A
K
K
T
E
---
N
K
D
Y
F
A
V
S
D
G
V
D
--
V
I
-
Y
-------
L
E
G
Q
N
E
K
G
K
-
E
D
P
H
A
W
L
N
L
E
N
G
I
I
F
A
K
N
I
A
K
Q
L
S
A
K
D
P
N
N
K
E
F
Y
E
K
N
L
K
E
Y
T
D
K
L
D
K
L
D
K
E
S
K
D
K
F
N
K
--
I
PA
E
--
K
K
L
I
V
T
S
E
G
A
F
K
Y
F
S
K
A
Y
G
V
P
S
A
Y
I
W
E
I
N
T
E
E
E
G
T
P
E
Q
I
K
T
L
V
E
K
L
R
Q
T
K
V
P
S
L
F
V
E
S
S
V
D
D
R
P
M
K
T
V
S
Q
D
T
N
I
---
P
I
Y
A
Q
I
F
T
---
D
S
I
A
--
E
Q
G
K
----
E
G
D
--
S
Y
Y
S
M
M
K
Y
N
L
D
K
I
A
E
G
L
A
62
HHSearch
63.82
29%
68
- C4 -
-
3ZK9
2
MTSA_STRPN
A:
[1-277]
------------------------------------
K
-
L
K
V
V
A
T
N
S
I
I
A
D
I
T
K
N
I
A
G
D
K
I
D
L
H
S
I
V
-
P
I
G
Q
D
P
H
E
Y
E
P
L
P
E
D
V
K
K
T
S
E
A
D
L
I
F
Y
N
G
I
N
L
E
T
GGNA
W
F
T
K
L
V
E
N
A
K
K
T
E
---
N
K
D
Y
F
A
V
S
D
G
V
D
V
I
Y
----------
L
E
G
Q
N
E
K
G
K
-
E
D
P
H
A
W
L
N
L
E
N
G
I
I
F
A
K
N
I
A
K
Q
L
S
A
K
D
P
N
N
K
E
F
Y
E
K
N
L
K
E
Y
T
D
K
L
D
K
L
D
K
E
S
K
D
K
F
N
K
--
I
PA
E
--
K
K
L
I
V
T
S
E
G
A
F
K
Y
F
S
K
A
Y
G
V
P
S
A
Y
I
W
E
I
N
T
E
E
E
G
T
P
E
Q
I
K
T
L
V
E
K
L
R
Q
T
K
V
P
S
L
F
V
E
S
S
V
D
D
R
P
M
K
T
V
S
Q
D
T
N
I
---
P
I
Y
A
---
Q
I
F
T
N
S
I
A
--
E
Q
G
K
----
E
G
D
--
S
Y
Y
S
M
M
K
Y
N
L
D
K
I
A
E
G
L
A