@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0979: (2018-01-02 )
MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLDADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMYLKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDLIQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGKVFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED
Atome Classification :
(66 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120....----------------------------------------------------------------------.----------------------------------------------------------------------.-------------------------------------------------------.--------130------.........140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240..--....--.250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350...-....-360.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MATKQKE
V
T
T
F
D
V
Q
V
A
E
F
I
R
NHKQKGTATDDEIN
A
S
L
V
I
P
F
TL
D
A
D
G
I
E
D
L
L
Q
R
I
Q
DAG
I
S
I
TDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVN
D
P
V
R
M
Y
L
K
EIGVVPLLTNEEEK
E
L
A
L
A
V
EA----------------------------------------------------------------------G----------------------------------------------------------------------
D
-------------------------------------------------------
I
--------
E
--------
A
K
Q
R
L
A
E
A
N
L
R
L
V
V
S
I
A
K
R
Y
VGR
G
M
Q
F
L
D
L
I
Q
EGN
M
G
L
M
K
A
V
D
K
FDYSKGFKF
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
I
ADQA
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
V
R
E
Q
R
N
L
L
Q
E
LGQDP
T
P
E
Q
I
A
E
R
MD--M
T
P
D
--
K
V
R
E
I
L
K
I
A
QEPVSLETPIGEED
D
S
H
L
G
D
F
I
E
D
E
V
IENPV
D
Y
T
T
R
I
V
L
R
E
Q
L
D
E
I
L
D
T
L
TDREE
N
V
L
R
L
R
FGLDDGKM
R
T
L
E
D
V
G
K
V
F
N
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R-QPSR-SK
P
L
R
D
F
IED
98
HHSearch
77.19
65%
58
- C4 -
-
4XLN
1
SIGA_THEAQ
L:
[2-346]
-----------------------------------------------------------------------------------------------
S
D
P
V
R
Q
Y
L
H
E
I
G
Q
V
P
L
L
T
L
E
E
E
I
D
L
A
R
K
V
E
E
----------------------------------------------------------------------
G
MEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIARE
G
-------------------------------------------------------
E
--------
A
--------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
PG
W
D
A
K
--
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
-
Y
H
E
S
R
T
R
K
L
R
D
F
L
--
20
PsiBlast_PDB
76.40
67%
-123
- C4 -
-
4LK1
-
RPOD_ECOLI
F:
[369-612]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
F
L
D
-
13
PsiBlast_PDB
75.25
59%
33
- C4 -
-
5VI8
-
?
F:
[164-466]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
LYATQKLAELAEKGEKLPVQQRR-----------------------------------------------
D
-------------------------------------------------------
M
--------
Q
WICRDGDR
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
--
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
E
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
12
PsiBlast_PDB
75.22
59%
32
- C4 -
-
5TW1
-
?
F:
[164-466]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
LYATQKLAELAEKGEKLPVQQRR-----------------------------------------------
D
-------------------------------------------------------
M
--------
Q
WICRDGDR
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
--
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
E
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
21
PsiBlast_CBE
74.28
67%
-119
- C4 -
-
4KN4
1
RPOD_ECOLI
Y:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
22
PsiBlast_CBE
73.98
67%
-116
- C4 -
-
4KMU
1
RPOD_ECOLI
Y:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
18
PsiBlast_PDB
73.70
67%
-128
- C4 -
-
4KN4
1
RPOD_ECOLI
X:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
25
PsiBlast_CBE
73.52
67%
0
- C- -
-
4YLP
1
RPOD_ECOLI
F:
[384-628]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
F
L
D
D
24
PsiBlast_CBE
73.52
67%
0
- C- -
-
4YLP
1
RPOD_ECOLI
L:
[384-628]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
F
L
D
D
19
PsiBlast_PDB
73.33
67%
-124
- C4 -
-
4KN7
1
RPOD_ECOLI
X:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
16
PsiBlast_PDB
73.13
67%
-124
- C4 -
-
4JK2
-
RPOD_ECOLI
X:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
34
PsiBlast_CBE
73.11
63%
0
- C- -
-
2A68
1
?
F:
[166-423]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
-----
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
33
PsiBlast_CBE
73.11
63%
0
- C- -
-
2A68
1
?
P:
[166-423]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
-----
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
32
PsiBlast_CBE
73.11
63%
0
- C- -
-
2A69
1
?
F:
[166-423]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
-----
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
15
PsiBlast_PDB
73.03
67%
-121
- C4 -
-
4JK1
-
RPOD_ECOLI
X:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
17
PsiBlast_PDB
72.96
67%
-126
- C4 -
-
4KMU
-
RPOD_ECOLI
X:
[369-609]
----------------------------------------------------------------------------------------------------------------------------
E
A
----------------------------------------------------------------------
K
----------------------------------------------------------------------
A
-------------------------------------------------------
R
--------
R
--------
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
Q
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
D
K
F
E
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
S
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
--
M
P
E
D
--
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
L
P
L
D
S
A
T
T
E
S
L
R
A
A
T
H
D
V
L
A
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
V
T
R
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
-
H
P
S
R
-
S
E
V
L
R
S
----
99
HHSearch
72.22
65%
20
- C4 -
-
1L9U
-
SIGA_THEAQ
H:
[2-332]
-----------------------------------------------------------------------------------------------
S
D
P
V
R
Q
Y
L
H
E
I
G
Q
V
P
L
L
T
L
E
E
E
I
D
L
A
R
K
V
E
E
----------------------------------------------------------------------
G
----------------------------------------------------------------------
M
EAIKKLSEATGLDQELIREVVRAKILGTARVEEVDGKLKSLPKELKRYLHIAREG
E
--------
A
--------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
PG
W
D
A
K
--
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
---------
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
-
Y
H
E
S
R
T
R
K
L
R
D
F
L
E
-
4
PsiBlast_PDB
72.15
59%
43
- C4 -
-
5UH9
2
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
5
PsiBlast_PDB
72.14
59%
42
- C4 -
-
5UHA
2
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
9
PsiBlast_PDB
71.94
59%
42
- C4 -
-
5UHE
2
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
7
PsiBlast_PDB
71.72
59%
41
- C4 -
-
5UHC
3
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
11
PsiBlast_PDB
71.37
59%
42
- C4 -
-
5UHG
2
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
-
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
1
PsiBlast_PDB
71.36
59%
41
- C4 -
-
5UH5
2
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
2
PsiBlast_PDB
71.22
59%
41
- C4 -
-
5UH6
3
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
8
PsiBlast_PDB
70.60
59%
39
- C4 -
-
5UHD
2
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
--
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
10
PsiBlast_PDB
70.54
59%
44
- C4 -
-
5UHF
1
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
3
PsiBlast_PDB
70.41
59%
45
- C4 -
-
5UH8
3
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
G
D
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
6
PsiBlast_PDB
70.14
59%
39
- C4 -
-
5UHB
1
SIGA_MYCTU
F:
[226-528]
------------------------------------------------------------------------------------------------
D
S
V
R
A
Y
L
K
Q
I
G
K
V
A
L
L
N
A
E
E
E
V
E
L
A
K
R
I
E
A
----------------------------------------------------------------------
G
L
Y
A
T
Q
L
M
T
E
L
S
E
R
G
E
K
L
P
A
A
Q
R
R
-----------------------------------------------
D
-------------------------------------------------------
M
M
W
I
C
R
D
G
D
R
--------
A
K
N
H
L
L
E
A
N
L
R
L
V
V
S
L
A
K
R
Y
T
G
R
G
M
A
F
L
D
L
I
Q
E
G
N
L
G
L
I
R
A
V
E
K
F
D
Y
T
K
G
Y
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
T
R
A
M
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
V
I
N
K
L
G
R
I
Q
R
E
L
L
Q
D
L
G
R
E
P
T
P
E
E
L
A
K
E
M
D
--
I
T
P
E
--
K
V
L
E
I
Q
Q
Y
A
R
E
P
I
S
L
D
Q
T
I
--
E
G
D
S
Q
L
G
D
F
I
E
D
S
E
A
V
V
A
V
D
A
V
S
F
T
L
L
Q
D
Q
L
Q
S
V
L
D
T
L
S
E
R
E
A
G
V
V
R
L
R
F
G
L
T
D
G
Q
P
R
T
L
D
E
I
G
Q
V
Y
G
V
T
R
E
R
I
R
Q
I
E
S
K
T
M
S
K
L
R
-
H
P
S
R
-
S
Q
V
L
R
D
Y
L
D
-
52
PsiBlast_CBE
68.69
63%
8
- C4 -
-
4OIQ
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
49
PsiBlast_CBE
68.65
63%
8
- C4 -
-
5D4C
1
?
P:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
56
PsiBlast_CBE
68.57
63%
0
- C4 -
-
4G7Z
2
?
P:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
42
PsiBlast_CBE
68.46
63%
0
- C4 -
-
5I2D
1
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
58
PsiBlast_CBE
68.41
63%
7
- C4 -
-
4G7O
2
?
P:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
41
PsiBlast_CBE
68.34
63%
10
- C4 -
-
5I2D
1
?
Q:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
30
PsiBlast_CBE
68.33
63%
7
- C4 -
-
4Q4Z
1
?
F:
[166-423]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
54
PsiBlast_CBE
68.27
63%
7
- C4 -
-
4OIO
2
?
F:
[186-441]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
---
51
PsiBlast_CBE
68.27
63%
11
- C4 -
-
4OIR
3
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
62
PsiBlast_CBE
68.12
65%
10
- C4 -
-
5TJG
1
?
F:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
28
PsiBlast_CBE
68.07
63%
-3
- C4 -
-
5VO8
2
?
F:
[166-423]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
61
PsiBlast_CBE
68.05
63%
14
- C4 -
-
4G7H
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
60
PsiBlast_CBE
68.02
63%
4
- C4 -
-
4G7H
2
?
P:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
59
PsiBlast_CBE
68.00
63%
14
- C4 -
-
4G7O
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
63
PsiBlast_CBE
67.93
65%
9
- C4 -
-
4XLS
1
SIGA_THEAQ
L:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
48
PsiBlast_CBE
67.86
63%
8
- C4 -
-
5D4D
1
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
55
PsiBlast_CBE
67.77
63%
7
- C4 -
-
4OIN
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
68
PsiBlast_CBE
67.73
65%
2
- C4 -
-
4XLN
1
SIGA_THEAQ
F:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
64
PsiBlast_CBE
67.55
65%
10
- C4 -
-
4XLS
1
SIGA_THEAQ
F:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
67
PsiBlast_CBE
67.54
65%
-1
- C4 -
-
4XLN
1
SIGA_THEAQ
L:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
66
PsiBlast_CBE
67.37
65%
-2
- C4 -
-
4XLR
1
SIGA_THEAQ
F:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
45
PsiBlast_CBE
67.35
63%
13
- C4 -
-
5D4E
1
?
P:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
50
PsiBlast_CBE
67.28
63%
14
- C4 -
-
5D4C
1
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
53
PsiBlast_CBE
67.24
63%
13
- C4 -
-
4OIP
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
65
PsiBlast_CBE
67.13
65%
-2
- C4 -
-
4XLR
1
SIGA_THEAQ
L:
[107-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
N
L
P
S
P
V
E
A
A
A
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
57
PsiBlast_CBE
66.86
63%
16
- C4 -
-
4G7Z
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
46
PsiBlast_CBE
66.50
63%
-0
- C4 -
-
5D4E
1
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
44
PsiBlast_CBE
66.09
63%
10
- C4 -
-
5E17
2
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
---------
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
43
PsiBlast_CBE
66.05
63%
0
- C4 -
-
5E18
1
?
F:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
-----------
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
29
PsiBlast_CBE
65.62
63%
2
- C4 -
-
4Q5S
1
?
F:
[166-422]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
A
K
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
-------
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
L
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
F
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
--
47
PsiBlast_CBE
62.24
63%
-31
- C4 -
-
5D4D
1
?
P:
[186-443]
---------------------------------------------------------------------------------------------------------------
L
P
K
E
H
K
R
Y
L
H
I
A
R
E
G
----------------------------------------------------------------------
E
----------------------------------------------------------------------
A
-------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
T
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
Q
E
P
V
S
L
E
T
P
I
G
D
E
K
D
S
F
Y
G
D
F
I
P
D
E
H
L
P
S
P
V
D
A
A
T
Q
S
L
L
S
E
E
L
E
K
-------
R
E
A
M
V
L
K
L
-----------------------
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
D
-
101
HHSearch
51.43
70%
17
- C4 -
-
3UGO
1
SIGA_THEAQ
A:
[5-184]
----------------------------------------------------------------------------------------------
T
S
D
P
V
R
Q
Y
L
H
E
I
G
Q
V
P
L
L
T
L
E
E
E
I
D
L
A
R
K
V
E
E
G
M
E
A
I
K
K
L
S
E
A
T
GLD
Q
E
L
I
R
E
V
V
R
A
K
I
LGTARIQKIPGLKEKPD
P
K
T
V
E
E
V
D
G
K
L
K
S
LP
K
E
L
K
R
Y
L
H
I
A
R
E
----------------------------------------------------------------------
G
-------------------------------------------------------
E
--------
A
--------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
50.68
73%
-75
- C4 -
-
4KI2
1
SIGA_THEAQ
B:
[111-239]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
T
I
R
I
P
V
H
M
V
E
T
I
N
K
L
S
R
T
A
R
Q
L
Q
Q
E
L
G
R
E
P
S
Y
E
E
I
A
E
A
M
G
--
P
G
W
D
AK
R
V
E
E
T
L
K
I
A
------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
50.18
73%
-155
- C4 -
-
3UGO
1
SIGA_THEAQ
A:
[111-184]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
50.06
73%
-154
- C4 -
-
4KI2
1
SIGA_THEAQ
A:
[111-183]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
49.71
73%
-152
- C4 -
-
3UGP
1
SIGA_THEAQ
A:
[111-184]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Q
H
L
I
E
A
N
L
R
L
V
V
S
I
A
K
K
Y
T
G
R
G
L
S
F
L
D
L
I
Q
E
G
N
Q
G
L
I
R
A
V
E
K
F
E
Y
K
R
R
F
K
F
S
T
Y
A
T
W
W
I
R
Q
A
I
N
R
A
I
A
D
Q
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
41.49
58%
-61
- C4 -
-
1KU7
2
SIGA_THEAQ
A:
[2-73]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
E
K
A
L
S
K
L
S
E
R
E
A
M
V
L
K
M
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
K
Y
H
E
S
R
-
T
R
K
L
R
D
F
L
E
-
79
PsiBlast_CBE
38.97
63%
-79
- C4 -
-
3N97
2
SIGA_THEAQ
A:
[9-61]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
L
S
E
R
E
A
M
V
L
K
M
R
K
G
L
I
D
G
R
E
H
T
L
E
E
V
G
A
Y
F
G
V
T
R
E
R
I
R
Q
I
E
N
K
A
L
R
K
L
R
-
H
P
-------------