@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1000: (2018-01-02 )
MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTRLLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMDSLVERGVFTKSER
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------.........10........20.-.....-.--------------.30----...------.-------------....--40...-.....50---.----.---......--.60-----------...-...-...70...-------------------------------..--...-80........90.......---.100.......110...---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------M
A
F
E
K
I
I
Q
L
KNC
R
Y
D
YTLSPS
V
-
K
K
F
T
L-K--------------DN
T
----
F
F
E
------T-------------KVG
N
--
Y
E
L
T
R
-
L
L
E
KVP----N----S---GE
G
F
Q
L
--
K
I
------------
I
I
N-KEL-TG
A
K
I
N
I
T-------------------------------DK--FG
L
-
R
L
V
D
I
FKSEDH
H
I
H
Q
E
K
F
Y
---
F
L
M
D
S
L
V
ERGVFTKSER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
88.69
31%
-119
- C4 -
-
2IAY
1
?
A:
[2-113]
--------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
T
T
T
V
K
L
D
G
D
T
K
T
Y
T
L
S
P
T
V
-
K
K
Y
T
L
-
M
--------------
D
L
G
----
F
V
K
------
G
-------------
R
S
G
A
--
F
S
F
E
R
-
S
L
D
P
T
S
----
P
----
Y
---
Q
A
A
F
K
L
--
K
M
------------
T
V
N
-
A
D
L
-
T
G
F
K
M
T
T
V
-------------------------------
T
G
--
N
G
V
-
Q
R
A
N
I
F
K
N
D
A
H
P
E
A
V
E
Q
L
R
---
Y
I
L
A
N
F
I
E
R
D
I
L
T
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.51
30%
-124
* C4 *
-
2IAY
1
?
A:
[3-112]
---------------------------------------------------------------------------------------------------------------------------------------------
A
Y
T
T
T
V
K
L
D
G
D
T
K
T
Y
T
L
S
P
T
V
-
K
K
Y
T
L
-
M
--------------
D
L
G
----
F
V
K
------
G
-------------
R
S
G
A
--
F
S
F
E
R
-
S
L
D
P
T
S
----
P
----
Y
---
Q
A
A
F
K
L
--
K
M
------------
T
V
N
-
A
D
L
-
T
G
F
K
M
T
T
V
-------------------------------
T
G
--
N
G
V
-
Q
R
A
N
I
F
K
N
D
A
H
P
E
A
V
E
Q
L
R
---
Y
I
L
A
N
F
I
E
R
D
I
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.80
36%
-180
* C9 *
-
5GPR
-
?
A:
[246-278]
----------------------------------------------------------------------------------------------------------------------------------------------
F
G
Q
L
M
M
L
K
Q
A
K
P
D
L
K
I
L
P
S
I
-
G
G
W
T
L
-
A
--------------
D
P
F
----
F
F
F
------
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
45.99
15%
-19
- C6 -
-
2NA4
-
CSGE_ECOLI
A:
[1-108]
-----------------------------------------------------------------------------------------------------------------------------------------------
A
V
E
V
E
V
P
G
L
L
T
D
H
T
V
S
S
I
G
-
H
D
F
Y
R
-
A
--------------
F
S
D
----
K
W
E
------
S
----------------
D
--
Y
T
G
N
L
-
T
I
N
E
R
P
----
S
----
A
---
R
A
G
S
W
I
--
T
I
------------
T
V
N
-
Q
D
V
-
I
F
Q
T
F
L
F
P
-------------------------------
L
K
RD
F
E
K
-
T
V
V
A
A
L
I
Q
T
E
E
A
L
N
R
R
Q
------
I
N
Q
A
L
L
S
T
G
D
L
A
H
D
E
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
45.49
23%
37
- C3 -
-
1G13
1
SAP3_HUMAN
A:
[1-162]
------------------------------------------------------------------------------------------------------------------------------------------------
S
S
F
S
W
D
N
C
--
D
E
G
K
D
P
A
V
I
R
S
L
T
L
-
E
--------------
P
D
P
----
I
I
V
------
P
---------------
G
N
--
V
T
L
S
V
M
G
S
T
S
V
P
----
L
----
S
---
S
P
-
L
K
V
--
D
L
------------
V
L
E
-
K
E
V
-
A
G
L
W
I
K
I
P
C
T
DYIGSCTFEH
F
C
D
V
L
D
M
L
I
PTGEPCPE
P
L
R
T
--
Y
G
L
-
P
C
H
C
P
F
K
E
G
T
Y
S
L
P
K
S
E
F
V
V
PD
L
E
L
P
S
W
L
T
T
G
N
Y
R
I
E
S
V
L
S
S
SGKRL
G
C
I
K
I
A
A
S
L
K
G
I-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.44
22%
13
- C1 -
-
3T2L
2
?
A:
[152-225]
------------------------------------------------------------------------------------------------------------------------------------------------
S
L
V
E
L
K
I
S
R
E
N
Y
F
M
P
C
E
I
-
S
K
I
T
L
-
K
N
SNLIK
K
G
T
I
NIAV
D
G
S
----
I
H
S
------
S
-------------
E
T
G
N
--
Y
D
L
T
T
-
V
T
D
A
S
P
----
H
----
T
L
S
V
G
E
S
Y
V
C
--
R
V
------------
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.39
33%
-
- C7 -
-
4WJ3
-
SYDND_PSEAE
M:
[463-522]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
A
N
P
----
G
----
A
---
A
L
S
R
A
Y
--
D
M
------------
V
L
N
G
T
E
L
-
G
G
G
S
I
R
I
H
-------------------------------
D
K
--
S
M
Q
-
Q
A
V
F
R
V
L
G
I
D
E
A
E
Q
E
E
K
F
G
---
F
L
L
D
A
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
43.92
16%
-31
* C5 *
-
5DIR
11
LSPA_PSEAE
A:
[21-177]
------------------------------------------------------------------------------------------------------------------PDVDRFGRLPWL
W
I
T
V
L
V
F
V
L
D
Q
V
S
K
A
F
F
Q
A
E
L
S
M
Y
Q
---
Q
I
V
V
I
P
D
L
-
F
S
W
T
L
-
A
--------------
Y
N
T
GAAF
S
F
L
------
A
-------------
D
S
S
G
--
W
Q
R
W
L
-
F
A
L
I
A
I
----
V
----
V
---
S
A
S
L
V
V
--
W
L
K
R
LKKGE
T
W
L
A
I
A
L
A
-
L
V
L
-
G
G
A
L
G
N
L
Y
-------------------------------
D
R
--
M
V
L
G
H
V
V
D
F
I
L
V
H
W
Q
N
R
W
Y
F
P
A
F
---
N
L
A
D
S
A
I
T
V
G
A
V
M
L
A
L
D
MF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
38.78
36%
-125
- C9 -
-
5GQB
4
?
A:
[246-278]
----------------------------------------------------------------------------------------------------------------------------------------------
F
G
Q
L
M
M
L
K
Q
A
K
P
D
L
K
I
L
P
S
I
-
G
G
W
T
L
-
A
--------------
D
P
F
----
F
F
F
------
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
37.78
17%
47
* C3 *
-
3RFU
-
COPA_LEGPH
A:
[74-736]
VSP
E
Y
L
D
M
R
R
R
F
W
I
A
L
M
L
T
I
P
V
V
I
L
E
M
G
GHGLKHFISGNG
S
S
W
I
Q
L
L
L
A
T
P
V
V
LWGG
W
P
F
F
K
R
G
W
Q
S
L
K
TGQLN
M
F
T
L
I
A
M
G
I
G
V
A
W
I
Y
S
M
V
A
V
L
WPGVFPHAFRSQEGVVAVY
F
E
A
A
A
V
I
T
T
L
V
L
L
G
Q
V
L
E
L
K
A
R
EQTG
S
A
I
R
A
L
L
K
L
V
P
E
S
A
H
R
I
K
E
D
G
S
-
E
E
E
V
S
-
L
--------------
D
N
V
---------------------------
A
V
G
D
--
L
L
R
V
R
-
P
G
E
K
I
P
----
V
----
D
---
G
E
V
Q
E
G
--
R
S
------------
F
V
D
-
E
S
M
V
T
G
E
P
I
P
V
A
-------------------------------
K
E
--
A
S
A
-
K
V
I
G
A
T
I
N
Q
T
G
S
F
V
M
K
A
L
H
---
V
G
S
D
T
M
L
A
R
I
V
Q
M
V
S
D
A
Q
R
SRA
P
I
Q
R
L
A
D
T
V
S
G
W
F
V
P
A
V
I
L
V
A
V
L
S
F
I
V
W
A
L
LGPQPALS
Y
G
L
I
A
A
V
S
V
L
I
I
A
CPCALGLA
T
P
M
S
I
M
V
G
V
G
K
G
A
Q
S
GVLIKN
A
E
A
L
E
R
M
E
K
VN
T
L
V
V
D
K
T
GTLTEG
H
P
K
L
T
R
I
V
T
D
DFV
E
D
N
A
L
A
L
A
A
A
L
E
H
QSEH
P
L
A
N
A
I
V
H
A
A
K
E
KGL
S
L
G
S
V
E
A
F
E
A
P
TGK
G
V
V
G
Q
V
DGH
H
V
A
I
G
N
A
R
L
M
Q
E
H
G
G
D
N
A
P
L
F
E
K
A
D
E
L
R
G
K
GA
S
V
M
F
M
A
V
DGKTV
A
L
L
V
V
E
DPIKSS
T
P
E
T
I
L
E
L
Q
Q
S
G
I
E
I
V
M
L
T
G
D
S
K
R
T
A
E
A
V
A
G
T
L
GIK
K
V
V
A
EIM
P
E
D
K
S
R
I
V
S
E
L
K
D
K
GLI
V
A
M
A
G
D
G
VND
A
P
A
L
A
K
AD
I
G
I
A
M
GTGTD
V
A
I
E
S
A
GVTLLHGDLRG
I
A
K
A
R
R
L
S
E
S
T
M
S
N
I
R
Q
N
L
F
F
A
F
I
Y
N
V
L
G
V
P
L
A
A
GVLYPLTGLLLS
P
M
I
A
A
A
A
M
A
L
S
S
V
S
V
I
I
N
A
L
R
LKRVTL
8
PsiBlast_PDB
37.66
26%
-90
- C4 -
-
2DX0
-
PLCG2_MOUSE
A:
[67-128]
--------------------------------------------------------------------------------------------------------------------------------------------
L
S
F
W
R
S
G
R
V
Q
H
C
R
I
R
S
T
M
E
N
G
V
-
M
K
Y
Y
L
-
T
--------------
D
N
L
----
T
F
N
------
S
I
Y
A
L
I
Q
H
Y
R
E
A
H
L
R
C
A
E
--
F
E
L
-
R
-
L
T
D
P
V
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
36.58
17%
-91
- C7 -
-
4B1X
-
M:
[19-30]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
E
Q
R
N
I
L
K
P
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
34.79
14%
47
* C6 *
-
5JIG
1
YQ77_SCHPO
A:
[1-127]
--------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
Y
T
F
N
E
L
V
V
L
D
Y
P
H
K
D
R
A
L
R
-
Y
L
E
R
L
-
R
--------------
D
D
T
----
G
I
K
------
K
-------------
I
M
D
S
H
R
W
T
V
P
L
-
L
S
E
M
D
P
TL
G
L
N
----
H
---
N
Q
G
A
H
I
--
E
L
------------
R
L
R
-
T
D
R
-
Y
D
G
-
F
R
D
Y
-------------------------------
K
T
--
V
K
S
-
T
L
I
H
E
L
T
H
N
V
H
G
E
H
D
S
S
F
W
---
E
L
F
R
Q
L
T
K
E
A
--
D
A
A
D
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
32.36
33%
10
* C7 *
-
4WJ4
1
SYDND_PSEAE
A:
[471-530]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
A
N
P
----
G
----
A
---
A
L
S
R
A
Y
--
D
M
------------
V
L
N
G
T
E
L
-
G
G
G
S
I
R
I
H
-------------------------------
D
K
--
S
M
Q
-
Q
A
V
F
R
V
L
G
I
D
E
A
E
Q
E
E
K
F
G
---
F
L
L
D
A
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
29.37
37%
-64
- C2 -
-
3IXQ
-
RPIA_METJA
A:
[171-212]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
-------------------------------
D
N
---
G
N
-
M
I
I
D
V
F
M
N
I
D
D
A
I
E
L
E
K
E
I
---
N
N
I
P
G
V
V
E
N
G
I
F
T
K
V
D
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
23.47
12%
4
- C8 -
-
1LTR
-
ELBH_ECOLX
F:
[15-53]
--------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
I
Y
T
I
N
D
K
I
-
L
S
Y
T
E
-
S
--------------
M
A
G
----
K
R
E
MVIITF
K
-------------
S
G
A
T
--
F
Q
V
E
V
-
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
21.15
12%
30
* C8 *
-
1LTB
-
ELBP_ECOLX
G:
[15-53]
--------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
I
Y
T
I
N
D
K
I
-
L
S
Y
T
E
-
S
--------------
M
A
G
----
K
R
E
MVIITF
K
-------------
S
G
E
T
--
F
Q
V
E
V
-
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
18.57
21%
92
- C5 -
-
1Y6U
-
?
A:
[6-64]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
I
W
-
E
R
Y
T
L
T
I
--------------
E
E
A
----
S
K
Y
------
F
-------------
R
I
G
E
--
N
K
L
R
R
-
L
A
E
E
N
K
----
N
----
A
---
N
W
L
I
M
N
GN
R
I
------------
Q
I
K
-
R
K
Q
-
F
E
K
I
I
D
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
15.90
19%
-
- C- -
-
3SD2
-
?
A:
[34-75]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
M
-
G
I
P
I
Q
P
----
T
Y
E
K
C
A
---
I
L
S
N
I
L
--
N
V
------------
S
F
G
-
R
A
K
-
D
Y
A
I
I
T
V
T
-------------------------------
N
K
A-
T
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
13.87
21%
39
- C4 -
-
2C34
-
?
A:
[89-112]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
--
L
V
Y
T
R
-
P
F
E
G
I
K
----
P
----
E
---
N
E
R
Y
T
L
--
H
L
------------
N
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------