@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1024: (2018-01-03 )
MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELETAYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHPTYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDITVRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQEASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVVIKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIPTNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFAANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGSKASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFAAEGSEILLRELKETGVNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVVVGADAGSKLQKAQELGIQVRDEAWLESL
Atome Classification :
(35 SA)
-----.........10........20........30........40........50........60.-.-..-....70........80........90......---.---.----100---.---......110.......120.......130.......140.......150.--------..-----.---.-.-.160.......170.......180.......190.......200.......210....-----...-----220.---..---....230.......240---.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380..-..-..-.390.......400.......410....-.-..420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520...--....530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----MN
K
R
M
N
E
L
V
A
L
L
N
R
Y
A
T
E
YYTSDNPSVS
D
S
E
Y
D
R
L
Y
R
E
L
V
E
L
ETAY
P
E
Q
V
LADSPTHRVG
G
K
-
V
-
L
D
-
G
F
E
K
Y
SHQYP
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
---E---V----AH
P
---
T
---
Y
I
C
E
L
K
ID
G
L
S
I
S
L
T
Y
EK
G
I
L
V
A
G
V
TRGDGSI
G
E
N
I
T
E
N
L
K
R
V
KDIPLTL--------PE-----E---L-
D
-
I
T
V
RGECYMPRA
S
F
D
Q
V
N
Q
A
R
QENGEPEFANPRNAAA
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y-----QEA-----SPST---RD---
S
Q
E
K
G
L
K
Y
L
E
QLGFVV
N
---
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
RENLPYDID
G
V
V
I
K
VNDLASQEEL
G
F
T
V
KAP
K
W
A
V
A
Y
KFPAEEKE
A
Q
L
L
S
V
D
WTVGR
T
G
V
VTPTANL
T
P
V
Q
L
AG
T
T
VSRATLHN
V
D
Y
I
A
E
KDIRKDD
T
V
I
V
Y
KAG
D
I
I
P
A
V
L
R
V
V
E
S
KRV-SE-EK-LDIPTNCPSCNSD
L
L
HFED
E
V
A
L
R
CINP-R-C
P
A
Q
I
M
E
G
L
I
H
F
ASRDAMNITGL
G
P
S
I
V
E
K
L
F
A
A
N
L
V
K
D
V
A
D
I
Y
R
LQEE
D
F
L
L
L
EGV
K
E
K
S
A
A
K
L
Y
Q
A
I
Q
ASKEN
S
A
E
K
L
L
F
G
L
G
I
R
H
VG
S
K
A
S
Q
L
L
L
Q
Y
F
H
S
I
E
N
L
Y
--QA
D
S
E
E
V
A
S
I
E
S
L
G
G
V
I
A
K
S
L
Q
T
Y
F
AAE
G
S
E
I
L
L
R
E
L
K
E
TGV
N
L
DYKG
Q
T
V
V
A
D
AALS
G
L
T
V
V
L
T
G
K
L
E
R
L
K
R
S
E
A
K
S
K
L
E
S
LGAKVTGSVSKKT
D
L
V
V
V
GADAG
S
K
L
Q
K
A
Q
E
LG
I
Q
VR
D
E
A
W
LESL
3
PsiBlast_PDB
69.76
42%
17
- C7 -
-
5TT5
1
DNLJ_ECOLI
A:
[24-606]
-----
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
-
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
---
L
-------V--
T
---
W
C
C
E
L
M
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
--------
H
G
-----
E
NIP
A
-
R
-
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
-----
G
V
G
VLE--
G
G
E
L
---
P
D
---
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
---
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
-
E
D
-
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
-
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
--
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
--
W
P
A
P
------------------------------------------------------------------------------
5
PsiBlast_PDB
69.55
40%
-5
- C7 -
-
4GLX
3
DNLJ_ECOLI
A:
[4-582]
-----
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
-----
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
--------------
T
---
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
--------
H
G
-----
E
NIP
A
-
R
-
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
-----
G
V
G
VLE--
G
G
E
L
---
P
D
---
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
---
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
-
E
D
-
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
-
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
--
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
------------------------------------------------------------------------------------
56
HHSearch
68.80
41%
2
- C7 -
-
4GLX
3
DNLJ_ECOLI
A:
[5-583]
------
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
-----
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
--------------
T
---
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
--------
H
G
E
N---
I
---
P
-
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
-----
G
V
G
-----
V
L
E
G
GEL
P
D
---
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
---
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
-
E
D
T
R
E
-
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
-
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
--
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
-----------------------------------------------------------------------------------
2
PsiBlast_PDB
68.67
42%
33
- C7 -
-
2OWO
3
DNLJ_ECOLI
A:
[4-586]
-----
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
-
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
---
L
----
K
N
N
EK
V
T
---
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
--------
H
G
-----
E
NIP
A
-
R
-
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
-----
G
V
G
VLE--
G
G
E
L
---
P
D
---
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
---
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
-
E
D
-
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
-
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
--
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
--
W
P
A
P
------------------------------------------------------------------------------
54
HHSearch
68.25
43%
29
- C7 -
-
5TT5
1
DNLJ_ECOLI
A:
[25-606]
------
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
-
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
L-------------V--
T
---
W
C
C
E
L
M
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
--------
H
G
E
N---
I
---
P
-
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
-----
G
V
G
-----
V
L
E
G
GEL
P
D
---
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
---
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
-
E
D
T
R
E
-
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
-
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
--
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
--------------------------------------------------------------------------------
22
PsiBlast_CBE
67.23
44%
37
- C7 -
-
1DGS
1
DNLJ_THEFI
B:
[7-581]
------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
E
---
A
----
E
A
P
---
S
L--
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
KGV-----
P
D
-----
R
---
L
-
E
---
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
-----
A
L
G
LGLGL
E
E
S
G
---
L
K
---
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
HCY
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
--
R
G
L
A
Q
-
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
-
G
K
-
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
K
-
E
G
K
V
H
-
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
--------------------------------------------------------------------------------
44
Fugue
66.61
43%
40
- C7 -
-
1DGS
1
DNLJ_THEFI
A:
[1-581]
MT
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
E
---
A
----
E
A
P
S
--
L
---
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
--
T
G
S
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
--------
K
G
-----
V
---
P
D
R
-
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
LGLG
L
G
L
-----
E
E
S
G
---
L
K
---
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
---
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
-
R
P
-
I
R
W
P
E
A
C
P
E
C
G
H
R
L
--
V
K
E
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
--------------------------------------------------------------------------------
23
PsiBlast_CBE
65.96
43%
31
- C7 -
-
1V9P
1
DNLJ_THEFI
B:
[7-584]
------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
A
---
L
----
G
R
K
---
R
PFL
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
KGV-----
P
D
-----
R
---
L
-
E
---
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
-----
A
L
G
LGL--
E
E
S
G
---
L
K
---
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
HGY
E
K
A
L
G
A
E
G
V
E
E
V
Y
---
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
-
G
E
-
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
-
E
G
K
V
H
-
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
--------------------------------------------------------------------------------
6
PsiBlast_PDB
65.85
43%
30
- C7 -
-
1V9P
1
DNLJ_THEFI
A:
[7-584]
------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
A
---
L
----
G
R
K
---
R
P
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
KGV-----
P
D
-----
R
---
L
-
E
---
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
-----
A
L
G
LGL--
E
E
S
G
---
L
K
---
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
---
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
-
G
E
-
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
-
E
G
K
V
H
-
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
--------------------------------------------------------------------------------
4
PsiBlast_PDB
65.84
44%
38
- C7 -
-
1DGS
1
DNLJ_THEFI
A:
[7-581]
------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
E
---
A
----
E
A
P
---
S
L
--
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
KGV-----
P
D
-----
R
---
L
-
E
---
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
-----
A
L
G
LGLGL
E
E
S
G
---
L
K
---
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
--
R
G
L
A
Q
-
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
-
G
K
-
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
K
-
E
G
K
V
H
-
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
--------------------------------------------------------------------------------
55
HHSearch
64.51
44%
37
- C7 -
-
1V9P
1
DNLJ_THEFI
B:
[7-581]
------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
L
E
P
-
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
A
LG-
R
----
K
R
P
F--
L
---
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
--------
K
G
-----
V
---
P
-
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
-----
A
L
G
-----
L
G
L
E
ESG
L
K
---
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
---
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
-
G
E
E
R
P
-
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
E
--
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
--
M
D
R
LL
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
-----------------------------------------------------------------------------------
21
PsiBlast_CBE
64.24
100%
-69
- C7 -
-
4GLW
2
DNLJ_STRZP
B:
[2-304]
------
N
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
-
V
-
L
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
---
E
---
V
----
A
H
P
---
T
---
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
--------
P
E
-----
E
---
L
-
D
-
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
-----
Q
E
A
-----
S
P
S
T
---
R
D
---
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
---
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
62.59
100%
-68
- C7 -
-
4GLW
1
DNLJ_STRZP
A:
[2-305]
------
N
K
R
M
N
E
-----------------------------
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
-
V
-
L
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
---
E
---
V
----
A
H
P
---
T
---
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
--------
P
E
-----
E
---
L
-
D
-
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
-----
Q
E
A
-----
S
P
S
T
---
R
D
---
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
---
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
59.29
58%
0
- C- -
-
1TAE
-
DNLJ_ENTFA
A:
[14-324]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
54.33
98%
31
- C7 -
-
4GLW
2
DNLJ_STRZP
B:
[2-304]
------
N
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
-
V
-
L
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
-------
E
----
V
A
H
P
--
T
---
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
--------
P
------
E
---
E
-
L
D
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
-----
Q
E
A
-----
S
P
S
T
---
R
D
---
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
---
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
53.70
58%
2
- C7 -
-
1TA8
2
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
53.59
58%
1
- C7 -
-
4EFE
2
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
53.26
58%
5
- C7 -
-
3BA9
5
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
53.24
58%
7
- C7 -
-
4EEQ
2
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
52.96
58%
7
- C7 -
-
4EFB
2
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
52.69
58%
7
- C7 -
-
3BA8
2
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
52.50
58%
5
- C7 -
-
3BAA
4
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
52.26
58%
4
- C7 -
-
3BAB
3
DNLJ_ENTFA
A:
[14-317]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
52.05
58%
6
- C7 -
-
4LH6
2
DNLJ_ENTFA
A:
[14-322]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
51.78
58%
6
- C7 -
-
4LH7
2
DNLJ_ENTFA
A:
[14-322]
--------
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
---
V
A
--
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
E
-----
P
---
I
-
S
-
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
DF---
G
P
M
K
---
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
HHSearch
51.11
59%
16
- C7 -
-
4LH6
2
DNLJ_ENTFA
A:
[12-323]
------
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
----
G
K
P
V
--
A
---
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
--------
T
------
E
---
P
-
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
-----
T
V
A
-----
D
F
G
P
MK-
A
K
---
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
---
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
49.91
52%
-12
- C7 -
-
5FPO
3
DNLJ_STAAU
A:
[4-309]
-----
L
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
-
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
-
A
-
Q
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
---
Q
---
I
----
G
N
V
---
E
---
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
--------
K
E
-----
P
---
L
-
N
-
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
-
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
SV---
N
D
F
-----
T
D
F
N
---
A
R
---
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
---
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
49.72
52%
-10
- C7 -
-
4CC6
1
DNLJ_STAAU
A:
[4-309]
-----
L
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
-
A
-
Q
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
---
Q
---
I
----
G
N
V
---
E
---
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
--------
K
E
-----
P
---
L
-
N
-
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
SV---
N
D
F
-----
T
D
F
N
---
A
R
---
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
---
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
49.46
52%
-10
- C7 -
-
4CC5
1
DNLJ_STAAU
A:
[4-309]
-----
L
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
-
A
-
Q
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
---
Q
---
I
----
G
N
V
---
E
---
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
--------
K
E
-----
P
---
L
-
N
-
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
SV---
N
D
F
-----
T
D
F
N
---
A
R
---
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
---
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
HHSearch
46.25
45%
12
* C7 *
-
3PN1
2
DNLJ_HAEIN
A:
[5-318]
------
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
LI
L
---
L
----
P
K
P
L--
T
---
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
--------
L
T
DN---
P
---
P
-
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
-----
G
I
G
-----
I
A
E
G
VDL
P
T
---
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
---
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
46.20
45%
23
- C7 -
-
3UQ8
2
DNLJ_HAEIN
A:
[3-321]
------
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
---
R
LIL
L
----
P
A
P
L--
T
---
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
--------
L
T
DN---
P
---
P
-
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
-----
G
I
G
-----
I
A
E
G
VDL
P
T
---
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
---
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
44.30
44%
36
- C7 -
-
3UQ8
2
DNLJ_HAEIN
A:
[2-319]
-----
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
---
R
---
L
ILLP
A
P
L
---
T
---
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTDNP---
P
A
-----
R
---
L
-
E
---
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
-----
G
I
G
-----
I
A
E
G
---
V
D
LPT
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
---
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
43.03
44%
34
- C7 -
-
3PN1
2
DNLJ_HAEIN
A:
[4-318]
-----
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
---
R
LIL
L
----
P
K
P
L--
T
---
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTDNP---
P
A
-----
R
---
L
-
E
---
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
-----
G
I
G
-----
I
A
E
G
---
V
D
LPT
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
---
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
41.56
38%
27
- C7 -
-
1ZAU
1
DNLJ_MYCTU
A:
[14-328]
------
L
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
-
G
F
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
---
E
---
V
----
G
D
A
A--
H
---
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
--------
T
P
G
D
DYP
V
---
P
-
E
V
L
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
R
M
I
C
H
-----
G
L
G
-----
H
V
E
G
FR-
P
A
---
T
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
---
E
H
T
T
L
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
39.10
40%
26
- C7 -
-
1ZAU
1
DNLJ_MYCTU
A:
[31-328]
-----------------------
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
G
F
-
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
---
E
---
V
GDA-
A
H
--------
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
P
G
D
DYPV
P
E
-----
V
---
L
-
E
---
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
R
M
I
C
H
GLGHV
E
G
F
-----
R
P
A
T
---------
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
---
E
H
T
T
L
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------