@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1061: (2018-01-04 )
MQLEISNRKRVSMKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGKQATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEELLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSNTNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN
Atome Classification :
(18 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200......-.210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420-........430.......440.......-450.......460.......470.-......480.......490...--.-----...500.......510.......520......-.530...----------....540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
Q
L
EISNR
K
R
V
S
M
K
IN
K
K
Y
LV
G
S
A
A
A
L
I
L
S
V
C
S
YELGL
Y
Q
A
R
TVKENN
R
V
S
Y
IDGKQATQKTENL
T
P
D
E
V
S
KREGINA
E
Q
I
V
I
K
I
TDQGYVTSHGD
H
Y
H
Y
YNGKV
P
Y
D
A
I
F
S
E
E
L
LMKDPNYKLK
D
E
D
I
V
N
EVKG
G
Y
V
I
K
VD
G
K
Y
Y
V
Y
LKDAAHADNVR
T
K
E
E
I
N
R
Q
K
Q
E
H
S
Q
HREGGTPRNDG
A
V
A
L
ARSQGRYTTDD
G
Y
I
F
N
A
S
D
I
-IEDTGD
A
Y
I
V
PHGD
H
Y
H
Y
IPKNEL
S
A
S
E
L
A
A
A
E
A
F
L
SGRGNLSNSR
T
Y
RRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSNTNSQASQSN
D
I
D
S
L
L
K
Q
L
Y
KLPLSQRHVESD
G
L
V
F
D
P
A
Q
I
T
SRTARGVAVPHGDH
Y
H
FI
P
Y
S
Q
M
S
E
L
E
E
R
I
A
R
I
I
P
L
R
YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAP
N
L
K
IDS
N
S
S
L
V
S
Q
L
V
R
KVGEG
Y
V
F
--EEKGI
S
R
Y
V
F
A
KDL
P
S
E
T
V
K
N
L
E
S
K
L
S
K
-
Q
E
SV
S
H
TLTAKKENVAPR
D
Q
E
F
Y
D
-
K
A
Y
N
L
L
T
E
A
H
K
A
L
F
ENKGRNS
D
--
F
-----
Q
A
L
D
K
L
L
E
R
LNDEST
N
K
E
K
L
V
D
D
L
L
A
F
LAPIT-
H
P
E
RLGK----------PNSQ
I
E
Y
T
E
D
E
V
R
I
A
Q
L
A
D
KYTTSDG
Y
I
FDEHDIISDEGD
A
Y
VTPHMGHSHWIGKDSLS
D
K
E
K
V
A
A
Q
A
YTKEKGILPPSPDADVKANPTG
D
S
A
A
A
I
Y
N
RVKGEKRI
P
L
V
RLPY
M
V
E
H
T
V
E
VKNG
N
L
IIPHKDHYHN
I
K
F
A
W
FDDHTYKAPNGY
T
L
E
D
L
F
A
T
I
K
Y
Y
V
EHPDERPHSNDGWGN
A
S
E
H
VLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQ
V
E
T
E
K
V
E
A
Q
L
K
E
A
E
V
L
L
A
KVTDSSLKAN
A
T
E
T
L
A
GLRNN
L
T
L
Q
I
MDNN
S
I
M
A
E
A
E
K
L
L
A
L
L
KGSNPSSVSKEKIN
9
Fugue
93.62
92%
-46
- C2 -
-
3ZFJ
-
?
A:
[12-130]
--------------------------------------------------
S
Y
I
D
G
D
Q
A
G
Q
K
A
E
N
L
T
P
D
E
V
S
K
R
E
G
I
N
A
E
Q
I
V
I
K
I
T
D
Q
G
Y
V
T
S
H
G
D
H
Y
H
Y
Y
N
G
K
V
P
Y
D
A
I
I
S
E
E
L
L
M
K
D
P
N
Y
Q
L
K
D
S
D
I
V
N
E
I
K
G
G
Y
V
I
K
V
D
G
K
Y
Y
V
Y
L
K
D
A
A
H
A
D
N
I
R
T
K
E
E
I
K
R
Q
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
91.81
91%
-46
- C2 -
-
3ZFJ
-
?
A:
[12-130]
--------------------------------------------------
S
Y
I
D
G
D
Q
A
G
Q
K
A
E
N
L
T
P
D
E
V
S
K
R
E
G
I
N
A
E
Q
I
V
I
K
I
T
D
Q
G
Y
V
T
S
H
G
D
H
Y
H
Y
Y
N
G
K
V
P
Y
D
A
I
I
S
E
E
L
L
M
K
D
P
N
Y
Q
L
K
D
S
D
I
V
N
E
I
K
G
G
Y
V
I
K
V
D
G
K
Y
Y
V
Y
L
K
D
A
A
H
A
D
N
I
R
T
K
E
E
I
K
R
Q
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.42
91%
-46
- C2 -
-
3ZFJ
-
?
A:
[12-130]
--------------------------------------------------
S
Y
I
D
G
D
Q
A
G
Q
K
A
E
N
L
T
P
D
E
V
S
K
R
E
G
I
N
A
E
Q
I
V
I
K
I
T
D
Q
G
Y
V
T
S
H
G
D
H
Y
H
Y
Y
N
G
K
V
P
Y
D
A
I
I
S
E
E
L
L
M
K
D
P
N
Y
Q
L
K
D
S
D
I
V
N
E
I
K
G
G
Y
V
I
K
V
D
G
K
Y
Y
V
Y
L
K
D
A
A
H
A
D
N
I
R
T
K
E
E
I
K
R
Q
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
64.95
100%
-124
- C2 -
-
2CS7
-
?
B:
[1-55]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
R
Y
T
T
D
D
G
Y
I
F
N
A
S
D
I
-
I
E
D
T
G
D
A
Y
I
V
P
H
G
D
H
Y
H
Y
I
P
K
N
E
L
S
A
S
E
L
A
A
A
E
A
F
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
63.99
100%
-120
- C2 -
-
2CS7
-
?
A:
[1-55]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
R
Y
T
T
D
D
G
Y
I
F
N
A
S
D
I
-
I
E
D
T
G
D
A
Y
I
V
P
H
G
D
H
Y
H
Y
I
P
K
N
E
L
S
A
S
E
L
A
A
A
E
A
F
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
63.99
100%
-120
- C2 -
-
2CS7
-
?
A:
[1-55]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
R
Y
T
T
D
D
G
Y
I
F
N
A
S
D
I
-
I
E
D
T
G
D
A
Y
I
V
P
H
G
D
H
Y
H
Y
I
P
K
N
E
L
S
A
S
E
L
A
A
A
E
A
F
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
63.61
100%
-126
* C2 *
-
2CS7
-
?
C:
[2-55]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
Y
T
T
D
D
G
Y
I
F
N
A
S
D
I
-
I
E
D
T
G
D
A
Y
I
V
P
H
G
D
H
Y
H
Y
I
P
K
N
E
L
S
A
S
E
L
A
A
A
E
A
F
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
46.74
52%
-90
- C2 -
-
2CS7
-
?
B:
[1-54]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
R
Y
T
T
D
D
G
Y
I
F
N
A
S
D
I
I
E
D
T
G
D
A
Y
I
V
P
H
G
D
H
Y
H
Y
I
P
K
N
E
L
S
A
S
E
L
A
A
A
E
A
F
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
46.37
52%
-95
- C2 -
-
2CS7
-
?
C:
[2-54]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
Y
T
T
D
D
G
Y
I
F
N
A
S
D
I
I
E
D
T
G
D
A
Y
I
V
P
H
G
D
H
Y
H
Y
I
P
K
N
E
L
S
A
S
E
L
A
A
A
E
A
F
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
35.76
20%
20
- C1 -
-
1AA7
-
M1_I34A1
A:
[1-158]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
L
T
E
V
E
T
Y
V
L
S
I
I
P
--------------------
S
G
P
L
K
A
E
I
A
Q
R
L
E
D
V
F
A
G
K
N
T
D
-
L
E
V
L
M
E
W
L
K
T
R
P
I
L
S
P
L
T
K
G
I
L
G
F
V
F
T
L
T
V
P
S
E
------
R
G
L
Q
R
-
R
R
F
V
Q
N
A
L
N
G
N
G
------
D
P
N
N
M
D
-
K
A
V
K
L
Y
R
K
L
K
R
E
I
T
F
H
G
A
K
E
I
S
--
L
-----
S
Y
S
A
G
A
L
A
S
C
M
G
L
I
Y
N
R
M
G
A
V
T
T
E
V
A
F
G
L
V
C
A
-
T
C
E
Q
I
A
D
----------
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
34.35
14%
-49
- C1 -
-
2JEE
-
ZAPB_ECOLI
A:
[3-80]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
E
V
F
E
K
L
E
A
K
V
Q
Q
-
A
I
D
T
I
T
L
L
Q
M
E
I
E
E
L
K
E
K
N
N
S
L
S
Q
-
E
V
Q
N
A
Q
H
Q
R
E
E
L
E
R
E
N
N
H
L
K
E
Q
--
Q
-----
N
G
W
Q
E
R
L
Q
A
L
L
G
R
M
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
31.26
15%
-62
- C1 -
-
2KEB
-
DPOA2_HUMAN
A:
[1-78]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
A
S
A
Q
Q
L
A
E
E
L
Q
I
F
G
L
D
C
E
--
E
-----
A
L
I
E
K
L
V
E
L
C
V
Q
Y
G
Q
N
E
E
G
M
V
G
E
L
I
A
F
C
T
S
T
H
-
K
V
G
L
T
S
E
----------
I
L
N
S
F
E
H
E
F
L
S
K
R
L
S
K
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
29.80
21%
-48
* C1 *
-
2P5T
-
PEZA_STRPN
A:
[67-158]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
P
V
E
D
Y
E
L
T
L
K
I
E
I
V
K
E
R
G
A
N
L
L
S
R
L
Y
R
Y
Q
D
S
Q
G
I
S
-------------------
I
D
D
E
S
N
P
W
I
L
M
S
D
D
L
S
D
L
I
H
T
N
I
Y
L
V
E
T
F
D
E
I
E
R
Y
S
G
Y
L
D
G
I
E
R
M
L
E
I
S
E
K
R
M
V
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
28.88
23%
-58
- C1 -
-
1Z65
-
PRND_MOUSE
A:
[1-30]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
N
R
L
G
T
W
W
V
A
I
L
C
M
L
L
A
S
H
L
S
T
V
K
A
R
G
I
K
8
HHSearch
28.53
24%
-21
- C2 -
-
3ZFJ
-
?
A:
[37-116]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
A
E
Q
I
V
I
K
I
T
D
Q
G
Y
V
T
S
H
G
D
H
Y
H
Y
Y
N
G
K
V
P
Y
D
-------
A
I
I
S
---------------------------------------------------
E
------------
E
L
---
L
M
K
D
P
N
Y
Q
L
K
D
S
D
I
V
N
E
I
K
G
G
Y
V
I
K
V
D
G
K
Y
Y
V
Y
L
K
D
A
A
H
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
28.00
15%
109
- C1 -
-
3NFQ
-
IWS1_YEAST
A:
[8-154]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
L
E
Q
Y
L
D
E
K
I
L
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L
K
D
E
M
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A
A
Q
L
D
I
D
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L
N
K
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I
E
T
G
D
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I
A
M
Q
K
V
K
L
L
P
K
V
V
S
V
L
S
K
A
N
L
A
D
T
I
--
L
D
N
N
L
L
Q
S
V
R
I
W
L
E
P
L
P
D
G
S
L
P
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F
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A
A
L
N
D
L
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V
K
T
E
H
L
K
E
S
G
L
G
R
V
V
I
F
Y
T
K
S
K
R
V
E
A
Q
L
A
R
L
A
E
K
L
I
A
E
W
T
R
P
I
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
18.57
17%
126
- C1 -
-
4M3L
4
TRI63_HUMAN
A:
[1-60]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
M
D
-
T
L
Y
A
I
L
D
E
K
K
S
E
L
L
Q
R
I
T
Q
E
Q
E
E
K
L
-----
S
F
I
E
A
L
I
Q
Q
Y
Q
E
Q
L
D
K
S
T
K
L
V
E
T
A
I
Q
S
L
D
E
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
15.03
16%
-6
- C2 -
-
1DFE
-
RL36_THETH
A:
[1-37]
--------------------------------------------------------------------------------------------------------------------------
M
K
V
R
A
S
V
K
R
I
C
D
K
C
K
V
I
R
R
H
G
R
V
Y
V
I
C
E
N
P
K
H
K
Q
R
Q
G
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