@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1119: (2018-01-05 )
MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIGLLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRKVEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAFVVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLSLVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQGNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM
Atome Classification :
(14 SA)
----------------------------------------------------------------------------.........10-........20........30------------------.........40--------..------......---50.......---------.60..--......----70---------.....--...80-------------....---------------..-..90--......----...100------.-..---------------------....110.-----------------------------......120..---...---..130...--------....---140..------.....150.....----------------..160-...--.--..-.170------..---------------......180......-.190.--...--------...--200.......210.......220.......230.....----------..240.......250.......260--........270----......-----.280....-----------.----------------------------..290---...------.....-----.300.......310..-------...-------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------MKN
K
R
I
F
K
D
FQ-AS
K
M
S
L
N
I
Y
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A
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A
F
T
L
Y
--------
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I
------
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L
I
---
G
L
A
R
N
F
G
EA---------
G
Q
N
L
A
--
T
Y
L
Q
T
L
----
H
Q
---------
S
LTDK--T
S
D
F
R
-------------
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I
L
G
---------------
L
L
-
A
F
G
---
F
I
L
N
T
V
----
F
R
W
T
R
K
------
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-
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K---------------------RP
I
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G
F
-----------------------------
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---
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F
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--------
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---
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----------------
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LKTD----------
T
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GVAGIHGAWNFAQG
N
L
F
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V---SGQPSG
T
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T
----FLPQGN-----QDWLSGGS-----------F----------------------------GIE-----
G
S
I
------
M
T
S
L
V
-----
L
L
L
L
I
V
Y
L
A
N
K
L
K
K
EN-------ERM-------------------------
16
Fugue
70.55
16%
-
- C3 -
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3U4T
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?
A:
[230-487]
-----------------------------------------------------------------------------
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-----------------------------------------------------------------------
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-------
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--------------------------
15
Fugue
62.34
19%
-24
- C6 -
-
4Z0V
6
PDE12_HUMAN
A:
[7-440]
---------------------------------------------------------------------PPAFT
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VLYPYCAPYALE
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---
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------
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----------------
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----------
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----
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F
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----------------------------
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-----
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C
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THQALPSVSHPSD
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10
Fugue
58.50
15%
-108
* C6 *
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4BWZ
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?
A:
[3-386]
--------------------------------------------------------------------------G
A
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---
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--------
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------
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----
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---------------
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---
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P
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L
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----
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------
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L
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L
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V
-----------------------------
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---
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E-------------
12
Fugue
57.22
17%
-11
- C2 -
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4U6D
20
?
A:
[28-409]
-------------------------------------------------------------------EGFPFILPK
E
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----------------------
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DYNGHD
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F
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N
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------------------------------
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GLS
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I--
9
Fugue
55.20
18%
-108
* C8 *
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5DOQ
3
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A:
[1-432]
MNGYDPV
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PQGFELKNG
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M
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------------------
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-----
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NP------------------
13
Fugue
54.84
20%
-109
- C8 -
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1YAR
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?
O:
[10-237]
--------------------------------------------------------------------------------------
K
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----------------------------------------------------------------------------------
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--------------------------------------------------------------
E
--------
Q
L
L
G
---
V
L
Q
R
Y
------
Q
D
L
C
H
N
V
Y
C
Q
A
E
T
----------------
I
R
T
V
I
A
I
R
I
--
P
--
E
H
-
K
E
E
-------
D
N
----------------------------
L
G
-
V
A
V
Q
H
--
A
V
L
--------
K
I
I
--
D
E
L
E
I
K
T
L
G
S
G
E
K
S
G
S
G
G
A
P
T
P
I
G
M
Y
--
A
L
R
E
Y
L
S
A
R
S
----------
T
V
E
D
K
L
L
--------------------
G
G
G
S
Q
S
P
S
L
L
L
----
E
L
R
Q
I
D
-----
A
D
F
M
L
K
V
E
-----------
L
----------------------------
A
T
T
-----
H
--------
L
S
T
M
V
-----
R
A
V
I
N
A
Y
L
L
N
W
K
K
L
I
Q
-------
P
R
T
GSDHMVS------------------
14
Fugue
52.95
17%
-124
- C4 -
-
3QNQ
8
?
A:
[3-434]
------------------------------------------------------------RFLEKYV
M
P
V
A
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
-
V
L
T
M
P
F
L
I
I
G
S
I
F
L
I
I
S
T
L
PIPGY
S
E
F
M
A
S
L
FGKN
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
--------
I
M
------
A
L
I
A
V
F
---
G
I
A
Y
R
L
G
E
Y
Y
KVD
A
L
A
S
G
A
L
S
L
V
--
T
F
L
L
A
T
----
P
F
---------
Q
V
A
Y
I
--
M
P
G
T
K
-------------
E
S
I
L
V
D
GVIP
A
A
L
M
G
SQG
L
F
V
-
A
M
I
---
I
A
I
I
S
T
----
E
I
Y
R
F
L
------
V
-
Q
K
---------------------
K
M
I
I
K
M
P
E
-----------------------------
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
---
P
G
F
I
V
V
T
V
--------
V
W
I
I
---
R
L
I
F
E
------
H
T
T
F
G
S
I
H
N
V
V
G
K
LL
Q
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
A
V
I
-
L
V
H
--
V
--
L
W
-
A
C
G
-------
I
H
---------------
G
A
T
I
V
G
G
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
--
I
A
F
Q
A
GQDVPN
T
I
T
--
A
Q
F
F
D
L
W
I
Y
M
G
G
S
G
A
T
L
A
L
V
V
G
M
L
L
F
A
R
S
Q
Q
L
K
S
L
G
R
---------------
L
S
I
A
P
G
I
F
N
I
N
E
M
V
T
F
G
M
P
I
---
V
M
N
P
L
L
L
I
P
F
I
----
V
V
P
V
V
L
-----
T
I
V
S
Y
F
A
M
-----------
E
W
GLVARPSGAAVTWTTPI
L
F
S
G
Y
L
G
S
G
G
K
I
S
-----
G
V
I
------
L
Q
L
V
N
-----
F
A
L
A
F
V
I
Y
L
P
F
L
K
I
W
D
-------
K
Q
K
I
A
E
E
K
GEA-----------------
6
HHSearch
40.62
23%
-500
- C7 -
-
2MFR
-
A:
[34-46]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
S
I
Y
L
F
L
R
K
R
Q
-------
P
---------------------------
17
Fugue
38.70
13%
9
- C5 -
-
2REU
-
T2S3_STAAU
A:
[5-258]
----------------------------------------------------------------------------
S
I
E
D
I
V
F
E
K
F
Q
-
P
Y
I
-----------------------------------------------------------------------------------------
N
W
S
I
D
--
K
L
C
E
H
F
----
S
I
---------
N
K
G
E
K
--
G
L
N
Y
R
-------------
I
A
S
A
---------------
I
L
-
N
K
S
---
S
I
V
V
K
T
----
V
H
F
N
K
K
NVNK
E
S
M
-
S
F
---------------------
G
A
F
K
F
E
E
L
-----------------------------
A
N
E
E
W
E
D
S
E
G
Y
---
P
S
A
---
Q
W
R
N
F
L
L
E
--------
T
R
F
L
---
F
F
V
V
K
------
E
D
E
D
G
V
D
I
F
K
--------------------
G
I
K
F
-
F
S
M
--
P
-------
E
-------
E
D
---------------
I
N
G
P
V
K
R
M
W
D
D
T
V
K
K
-
L
K
E
G
V
--
T
L
E
--------
A
V
P
--
D
----------
K
S
T
K
D
G
W
R
I
K
N
N
F
V
D
K
S
D
D
L
I
C
H
V
R
P
H
----------
T
N
-------------------------
N
R
D
Y
R
G
G
S
N
A
D
----
K
L
P
K
K
I
-----
N
W
I
N
R
P
D
S
-----------
D
----------------------------
D
Y
S
-----
D
E
W
------
M
T
K
Q
S
-----
F
W
I
N
N
D
Y
I
K
K
Q
V
E
D
L
L
-----------------------------------
1
PsiBlast_PDB
38.69
32%
-143
- C7 -
-
2AU3
-
DNAG_AQUAE
A:
[341-396]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
L
I
N
S
S
---------
G
E
L
F
E
--
T
L
I
K
T
A
----
R
E
---------
N
L
E
E
K
--
T
R
E
F
R
-------------
Y
Y
L
G
---------------
F
I
-
S
D
G
V
R
R
F
A
L
A
S
E
----
F
H
T
K
Y
K
------
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
Fugue
16.60
35%
-81
* C7 *
-
1B9P
-
A:
[1-34]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
-
A
V
E
---
L
R
S
P
G
I
----
S
R
F
R
R
K
------
I
-
A
K
---------------------
R
S
I
K
T
L
E
H
-----------------------------
K
R
E
N
A
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
15.38
18%
-87
- C7 -
-
5FN5
-
APH1A_HUMAN
C:
[72-99]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
--
F
--
G
A
-
A
V
S
-------
V
L
---------------
L
Q
E
V
-
F
R
F
A
Y
Y
K
L
L
K
-
K
A
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
9.00
20%
113
- C1 -
-
2L6W
-
B:
[28-37]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
M
L
W
Q
K
K
P
-------
R
---------------------------
5
HHSearch
7.67
18%
-
- C7 -
-
5A63
-
APH1A_HUMAN
C:
[72-99]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
--
F
--
G
A
-
A
V
S
-------
V
L
---------------
L
Q
E
V
-
F
R
F
A
Y
Y
K
L
L
K
-
K
A
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------