@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1166: (2018-01-06 )
MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADVALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPTIIMMVGLQGAGKTTFAGKLANKLKKEENARPLMVAADIYRPAAIDQLKTLGQQIDVPVFALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEILLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGTGEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDFIDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPDLLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLPKNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSMKRMANKMKKAKKKRK
Atome Classification :
(49 SA)
.........10........20----------.........30........40........50........60........70........80........----90--...----.....100.......110.......120.......130......-.140.......150.......-160.....-...-170.......180.......190.......200.......---------..210----...------.------.....220.......230.......240........250.......260.......270.......280.......290.......300.......310...-.....320....-...330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
A
F
E
S
L
T
E
R
L
Q
N
V
F
K
N
L
R
KK-----------GKI
S
E
S
D
V
Q
E
A
T
K
E
I
R
L
A
L
L
EADVA
L
P
V
V
K
D
F
I
K
K
V
R
E
RAV
G
H
E
V
I
D
TL
N
P
A
Q
Q
I
I
K
I
V
D
E
E
L
T
A
V
LGS----
D
T
--
A
E
I
----
I
KSPKI
P
T
I
I
M
M
V
GLQGAGKT
T
F
A
G
K
L
A
N
K
L
K
K
EENAR
P
L
M
V
A
A-DIYRP
A
A
I
D
Q
L
K
T
L
G
Q
QIDV
P
-
V
F
-ALGTE-V
P
A
-
V
E
I
V
R
Q
G
L
E
Q
AQTNHN
D
Y
V
L
I
DTAGR
L
Q
I
D
E
--
L
L
M
N
E
L
R
---------
D
V
K
------
A
LA------Q------P
N
E
I
L
L
V
V
D
A
M
I
G
Q
E
A
A
N
V
A
R
E
FNA
Q
L
-
E
V
T
G
V
I
L
T
K
IDGDTRG
G
A
A
L
S
V
R
HITGK
P
I
K
F
TGTGE
K
I
T
DIETF
H
P
D
R
M
S
S
R
ILG
M
G
D
M
L
T
L
I
E
K
A
S
Q
-
E
Y
D
E
-
Q
K
A
L
E
M
A
E
K
M
R
E-NTF
D
F
N
D
F
I
D
Q
L
D
Q
VQNMG
P
M
E
D
L
L
K
MIPGMANNPALQNMK
V
D
E
R
Q
I
A
R
K
R
A
I
V
SSMTPEERENPDLL
N
P
S
R
R
R
R
IAAGSGN
T
F
V
E
V
N
K
F
I
K
D
F
N
Q
A
K
Q
L
M
Q
G
V
MSG
D
M
N
K
M
M
K
QMGINPNNLPKNMPNMGGM
D
M
S
A
L
E
G
M
MGQGGMP
D
L
S
ALGGAGMP
D
M
S
Q
M
FGGGLKG
K
I
G
E
F
A
M
K
Q
S
M
K
R
M
A
N
K
M
K
K
A
K
KKRK
21
PsiBlast_CBE
89.61
48%
-85
- C7 -
-
2XXA
2
SRP54_ECOLI
C:
[7-421]
-------
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
----
E
N
--
Q
T
L
----
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
-
P
S
D
V
G
-
Q
K
P
-
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
--
A
M
M
D
E
I
K
---------
Q
V
H
------
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
-
K
V
D
R
-
A
Q
A
E
K
L
A
S
K
L
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
----------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.76
48%
-78
- C7 -
-
2XXA
2
SRP54_ECOLI
A:
[4-421]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
----
E
N
--
Q
T
L
----
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
-
P
S
D
V
G
-
Q
K
P
-
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
--
A
M
M
D
E
I
K
---------
Q
V
H
------
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
-
K
V
D
R
-
A
Q
A
E
K
L
A
S
K
L
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
---------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
------------------------------------------------------------------------------------------------------
93
HHSearch
87.59
52%
-112
- C7 -
-
4C7O
3
SRP54_ECOLI
C:
[2-298]
--
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
----
E
N
--
Q
T
L
----
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
-
P
S
D
V
G
-
Q
K
P
-
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
--
A
M
M
D
E
I
K
---------
Q
V
H
------
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
87.23
51%
-112
- C7 -
-
4C7O
3
SRP54_ECOLI
C:
[2-298]
--
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
----
E
N
--
Q
T
L
----
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
-
P
S
D
V
G
-
Q
K
P
-
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
--
A
M
M
D
E
I
K
---------
Q
V
H
------
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
86.52
46%
-86
- C7 -
-
2FFH
-
SRP54_THEAQ
A:
[2-416]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
-
A
------------
E
L
------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
P
-----
Q
G
L
K
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
---------------------------------------------------------------------------------------------
91
HHSearch
86.07
35%
-80
- C7 -
-
3DM5
2
SRP54_PYRFU
A:
[1-435]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
----
E
A
--
K
P
I
-----
E
I
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
-
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
-
G
N
P
Q
E
-
K
D
A
-
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
--
A
L
I
E
E
M
K
---------
Q
I
S
------
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
-
L
E
K
E
V
E
I
K
E
E
D
I
E
R
F
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-------------------
I
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
------------
Q
M
K
K
L
F
K
S
M
N
K
R
Q
--
L
S
-------------------------------------------------------------------------
8
PsiBlast_PDB
85.91
34%
-80
- C7 -
-
3DM5
2
SRP54_PYRFU
A:
[1-435]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
----
E
---
A
K
P
----
I
E
I
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
-
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
-
G
N
P
Q
E
-
K
D
A
-
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
--
A
L
I
E
E
M
K
---------
Q
I
S
------
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
-
E
I
K
E
E
D
I
E
R
F
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-------------------
I
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
S
---------------------------------------------------------------------------------------
26
PsiBlast_CBE
85.19
34%
-85
- C7 -
-
3DM5
2
SRP54_PYRFU
B:
[1-434]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
----
E
---
A
K
P
----
I
E
I
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
-
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
-
G
N
P
Q
E
-
K
D
A
-
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
--
A
L
I
E
-
M
K
---------
Q
I
S
------
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
-
E
I
K
E
E
D
I
E
R
F
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
--------------------
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
----------------------------------------------------------------------------------------
92
HHSearch
84.93
35%
-84
- C7 -
-
3DM5
2
SRP54_PYRFU
B:
[1-434]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
----
E
A
--
K
P
I
-----
E
I
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
-
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
-
G
N
P
Q
E
-
K
D
A
-
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
--
A
L
I
E
-
M
K
---------
Q
I
S
------
N
V
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
-
L
E
K
E
V
E
I
K
E
E
D
I
E
R
F
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
--------------------
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
------------
Q
M
K
K
L
F
K
S
M
N
K
R
Q
--
L
--------------------------------------------------------------------------
4
PsiBlast_PDB
84.21
51%
-112
- C7 -
-
4C7O
2
SRP54_ECOLI
A:
[4-296]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
----
E
N
--
Q
T
L
----
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
-
P
S
D
V
G
-
Q
K
P
-
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
--
A
M
M
D
E
I
K
---------
Q
V
H
------
A
S
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
83.23
48%
-115
- C7 -
-
1JPN
3
SRP54_THEAQ
A:
[2-296]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
82.42
48%
-111
- C7 -
-
1RY1
-
SRP54_THEAQ
U:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
82.30
48%
-119
- C7 -
-
1FFH
-
SRP54_THEAQ
A:
[1-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
-------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
82.29
48%
-118
- C7 -
-
1JPN
3
SRP54_THEAQ
B:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
82.13
48%
-113
- C7 -
-
1NG1
8
SRP54_THEAQ
A:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
81.89
48%
-111
- C7 -
-
1JPJ
1
SRP54_THEAQ
A:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
81.82
48%
-116
- C7 -
-
3NG1
2
SRP54_THEAQ
A:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
81.81
48%
-119
- C7 -
-
3ZN8
-
SRP54_THEAQ
A:
[1-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
-------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107
HHSearch
81.61
50%
-121
- C7 -
-
5L3R
2
SR54C_ARATH
C:
[27-300]
--------------------------------
V
L
T
K
D
N
I
A
E
P
M
R
D
I
R
R
A
L
L
E
A
D
V
S
L
P
V
V
R
R
F
V
Q
S
V
S
D
Q
A
V
G
M
G
-----
K
P
D
Q
Q
L
V
K
I
V
H
D
E
L
V
K
L
M
G
G
----
E
V
--
S
E
L
----
Q
F
A
K
S
G
P
T
V
I
L
L
A
G
L
Q
G
V
G
K
T
T
V
C
A
K
L
A
C
Y
L
K
K
Q
-
G
K
S
C
M
L
I
A
G
-
D
V
Y
R
P
A
A
I
D
Q
L
V
I
L
G
E
Q
V
G
V
P
-
V
Y
-
T
A
G
T
D
-
V
K
P
-
A
D
I
A
K
Q
G
L
K
E
A
K
K
N
N
V
D
V
V
I
M
D
T
A
G
R
L
Q
I
D
K
--
G
M
M
D
E
L
K
---------
D
V
K
------
K
F
L
------
N
------
P
T
E
V
L
L
V
V
D
A
M
T
G
Q
E
A
A
A
L
V
T
T
F
N
V
E
I
-
G
I
T
G
A
I
L
T
K
L
D
G
D
S
R
G
G
A
A
L
S
V
K
E
V
S
G
K
P
I
K
L
V
G
R
G
E
R
M
E
D
L
E
P
F
Y
P
D
R
M
A
G
R
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
81.50
38%
0
- C- -
-
3NDB
-
SRP54_METJA
B:
[1-431]
--
M
D
K
L
G
E
N
L
N
K
A
L
N
K
L
K
A
A
-----------
A
F
V
D
K
K
L
I
K
E
V
I
K
D
I
Q
R
A
L
I
Q
A
D
V
N
V
K
L
V
L
K
M
S
K
E
I
E
R
R
A
L
E
E
K
T
P
K
G
L
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
V
K
L
L
G
E
----
E
A
--
K
K
L
----
E
L
N
P
K
K
Q
N
V
I
L
L
V
G
I
Q
G
S
G
K
T
T
T
A
A
K
L
A
R
Y
I
Q
K
R
-
G
L
K
P
A
L
I
A
A
-
D
T
Y
R
P
A
A
Y
E
Q
L
K
Q
L
A
E
K
I
H
V
P
-
I
Y
-
G
D
E
T
R
-
T
K
S
P
V
D
I
V
K
E
G
M
E
K
F
K
--
K
A
D
V
L
I
I
D
T
A
G
R
H
K
E
E
K
--
G
L
L
E
E
M
K
---------
Q
I
K
------
E
I
T
------
N
------
P
D
E
I
I
L
V
I
D
G
T
I
G
Q
Q
A
G
I
Q
A
K
A
F
K
E
A
V
G
E
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
E
T
K
A
P
I
K
F
I
G
I
G
E
G
I
D
D
L
E
P
F
D
P
K
K
F
I
S
R
L
L
G
M
G
D
L
E
S
L
L
E
K
A
E
D
-
M
V
D
E
--
K
T
E
E
S
I
D
A
I
M
R
-
G
K
F
T
L
N
E
L
M
T
Q
L
E
A
I
E
N
M
-----------------------
L
T
E
A
K
I
K
K
Y
K
V
I
I
S
S
M
T
K
E
E
R
E
N
P
K
I
I
K
A
S
R
I
R
R
I
A
R
G
S
G
T
T
E
N
D
V
R
E
V
L
R
Y
Y
E
T
T
K
---------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
81.43
48%
-116
- C7 -
-
2J7P
1
SRP54_THEAQ
B:
[4-294]
----
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
81.33
50%
-120
- C7 -
-
5L3R
2
SR54C_ARATH
C:
[27-300]
--------------------------------
V
L
T
K
D
N
I
A
E
P
M
R
D
I
R
R
A
L
L
E
A
D
V
S
L
P
V
V
R
R
F
V
Q
S
V
S
D
Q
A
V
G
M
G
-----
K
P
D
Q
Q
L
V
K
I
V
H
D
E
L
V
K
L
M
G
G
----
E
V
--
S
E
L
----
Q
F
A
K
S
G
P
T
V
I
L
L
A
G
L
Q
G
V
G
K
T
T
V
C
A
K
L
A
C
Y
L
K
K
Q
G
K
S
-
C
M
L
I
A
G
-
D
V
Y
R
P
A
A
I
D
Q
L
V
I
L
G
E
Q
V
G
V
P
-
V
Y
-
T
A
G
T
D
-
V
K
P
-
A
D
I
A
K
Q
G
L
K
E
A
K
K
N
N
V
D
V
V
I
M
D
T
A
G
R
L
Q
I
D
K
--
G
M
M
D
E
L
K
---------
D
V
K
------
K
F
L
------
N
------
P
T
E
V
L
L
V
V
D
A
M
T
G
Q
E
A
A
A
L
V
T
T
F
N
V
E
I
-
G
I
T
G
A
I
L
T
K
L
D
G
D
S
R
G
G
A
A
L
S
V
K
E
V
S
G
K
P
I
K
L
V
G
R
G
E
R
M
E
D
L
E
P
F
Y
P
D
R
M
A
G
R
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
81.20
48%
-110
- C7 -
-
2J7P
4
SRP54_THEAQ
A:
[3-294]
---
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
80.87
50%
-120
- C7 -
-
5L3R
2
SR54C_ARATH
A:
[30-301]
-----------------------------------
K
D
N
I
A
E
P
M
R
D
I
R
R
A
L
L
E
A
D
V
S
L
P
V
V
R
R
F
V
Q
S
V
S
D
Q
A
V
G
M
G
-----
K
P
D
Q
Q
L
V
K
I
V
H
D
E
L
V
K
L
M
G
G
----
E
V
--
S
E
L
----
Q
F
A
K
S
G
P
T
V
I
L
L
A
G
L
Q
G
V
G
K
T
T
V
C
A
K
L
A
C
Y
L
K
K
Q
G
K
S
-
C
M
L
I
A
G
-
D
V
Y
R
P
A
A
I
D
Q
L
V
I
L
G
E
Q
V
G
V
P
-
V
Y
-
T
A
G
T
D
-
V
K
P
-
A
D
I
A
K
Q
G
L
K
E
A
K
K
N
N
V
D
V
V
I
M
D
T
A
G
R
L
Q
I
D
K
--
G
M
M
D
E
L
K
---------
D
V
K
------
K
F
L
------
N
------
P
T
E
V
L
L
V
V
D
A
M
T
G
Q
E
A
A
A
L
V
T
T
F
N
V
E
I
-
G
I
T
G
A
I
L
T
K
L
D
G
D
S
R
G
G
A
A
L
S
V
K
E
V
S
G
K
P
I
K
L
V
G
R
G
E
R
M
E
D
L
E
P
F
Y
P
D
R
M
A
G
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
80.84
48%
-116
- C7 -
-
3NG1
2
SRP54_THEAQ
B:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
80.60
48%
-106
- C7 -
-
2NG1
4
SRP54_THEAQ
A:
[1-293]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
80.40
48%
-115
- C7 -
-
1OKK
6
SRP54_THEAQ
A:
[4-293]
----
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
-
E
V
M
D
G
-
E
S
P
-
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
77.04
49%
-70
- C7 -
-
1LS1
3
SRP54_THEAQ
A:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
G
E
-
S
P
E
--
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
75.39
49%
-55
- C7 -
-
1O87
5
SRP54_THEAQ
B:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
G
E
-
S
P
E
--
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
75.22
49%
-63
- C7 -
-
1O87
4
SRP54_THEAQ
A:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
G
E
-
S
P
E
--
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
72.98
31%
-120
- C7 -
-
5L3Q
5
SRP54_HUMAN
A:
[30-302]
----------------------------------
N
E
E
V
L
N
A
M
L
K
E
V
C
T
A
L
L
E
A
D
V
N
I
K
L
V
K
Q
L
R
E
N
V
K
S
A
I
D
--------
N
K
R
K
M
I
Q
H
A
V
F
K
E
L
V
K
L
V
D
P
----
G
V
--
K
A
W
----
T
P
T
K
G
K
Q
N
V
I
M
F
V
G
L
Q
G
S
G
K
T
T
T
C
S
K
L
A
Y
Y
Y
Q
R
K
-
G
W
K
T
C
L
I
C
A
-
D
T
F
R
A
G
A
F
D
Q
L
K
Q
N
A
T
K
A
R
I
P
-
F
Y
-
G
S
Y
T
E
-
M
D
P
-
V
I
I
A
S
E
G
V
E
K
F
K
N
E
N
F
E
I
I
I
V
D
T
S
G
R
H
K
Q
E
D
--
S
L
F
E
E
M
L
---------
Q
V
A
------
N
A
I
------
Q
------
P
D
N
I
V
Y
V
M
D
A
S
I
G
Q
A
C
E
A
Q
A
K
A
F
K
D
K
V
-
D
V
A
S
V
I
V
T
K
L
D
G
H
A
K
G
G
G
A
L
S
A
V
A
A
T
K
S
P
I
I
F
I
G
T
G
E
H
I
D
D
F
E
P
F
K
T
Q
P
F
I
S
K
L
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
72.75
40%
-63
- C7 -
-
5L3V
1
SRP54_SULSO
B:
[26-299]
-----------------------------------
E
K
A
V
D
E
F
I
K
D
L
Q
K
S
L
I
S
S
D
V
N
V
K
L
V
F
S
L
T
A
K
I
K
E
R
L
N
K
E
K
P
P
S
V
L
E
R
K
E
W
F
I
S
I
V
Y
D
E
L
S
K
L
F
G
G
----
D
K
--
E
P
N
----
V
N
P
T
K
L
P
F
I
I
M
L
V
G
V
Q
G
S
G
K
T
T
T
A
G
K
L
A
Y
F
Y
K
K
R
-
G
Y
K
V
G
L
V
A
A
-
D
V
Y
R
P
A
A
Y
D
Q
L
L
Q
L
G
N
Q
I
G
V
Q
-
V
Y
-
G
E
P
N
N
-
Q
N
P
-
I
E
I
A
K
K
G
V
D
I
F
V
K
N
K
M
D
I
I
I
V
D
T
A
G
R
H
G
Y
G
E
E
T
K
L
L
E
E
M
K
---------
E
M
Y
------
D
V
L
------
K
------
P
D
D
V
I
L
V
I
D
A
S
I
G
Q
K
A
Y
D
L
A
S
R
F
H
Q
A
S
-
P
I
G
S
V
I
I
T
K
M
D
G
T
A
K
G
G
G
A
L
S
A
V
V
A
T
G
A
T
I
K
F
I
G
T
G
E
K
I
D
E
L
E
T
F
N
A
K
R
F
V
S
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
72.00
40%
-57
- C7 -
-
5L3V
1
SRP54_SULSO
A:
[26-299]
-----------------------------------
E
K
A
V
D
E
F
I
K
D
L
Q
K
S
L
I
S
S
D
V
N
V
K
L
V
F
S
L
T
A
K
I
K
E
R
L
N
K
E
K
P
P
S
V
L
E
R
K
E
W
F
I
S
I
V
Y
D
E
L
S
K
L
F
G
G
----
D
K
--
E
P
N
----
V
N
P
T
K
L
P
F
I
I
M
L
V
G
V
Q
G
S
G
K
T
T
T
A
G
K
L
A
Y
F
Y
K
K
R
-
G
Y
K
V
G
L
V
A
A
-
D
V
Y
R
P
A
A
Y
D
Q
L
L
Q
L
G
N
Q
I
G
V
Q
-
V
Y
-
G
E
P
N
N
-
Q
N
P
-
I
E
I
A
K
K
G
V
D
I
F
V
K
N
K
M
D
I
I
I
V
D
T
A
G
R
H
G
Y
G
E
E
T
K
L
L
E
E
M
K
---------
E
M
Y
------
D
V
L
------
K
------
P
D
D
V
I
L
V
I
D
A
S
I
G
Q
K
A
Y
D
L
A
S
R
F
H
Q
A
S
-
P
I
G
S
V
I
I
T
K
M
D
G
T
A
K
G
G
G
A
L
S
A
V
V
A
T
G
A
T
I
K
F
I
G
T
G
E
K
I
D
E
L
E
T
F
N
A
K
R
F
V
S
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
71.56
31%
-121
- C7 -
-
5L3Q
5
SRP54_HUMAN
C:
[30-302]
----------------------------------
N
E
E
V
L
N
A
M
L
K
E
V
C
T
A
L
L
E
A
D
V
N
I
K
L
V
K
Q
L
R
E
N
V
K
S
A
I
D
--------
N
K
R
K
M
I
Q
H
A
V
F
K
E
L
V
K
L
V
D
P
----
G
V
--
K
A
W
----
T
P
T
K
G
K
Q
N
V
I
M
F
V
G
L
Q
G
S
G
K
T
T
T
C
S
K
L
A
Y
Y
Y
Q
R
K
-
G
W
K
T
C
L
I
C
A
-
D
T
F
R
A
G
A
F
D
Q
L
K
Q
N
A
T
K
A
R
I
P
-
F
Y
-
G
S
Y
T
E
-
M
D
P
-
V
I
I
A
S
E
G
V
E
K
F
K
N
E
N
F
E
I
I
I
V
D
T
S
G
R
H
K
Q
E
D
--
S
L
F
E
E
M
L
---------
Q
V
A
------
N
A
I
------
Q
------
P
D
N
I
V
Y
V
M
D
A
S
I
G
Q
A
C
E
A
Q
A
K
A
F
K
D
K
V
-
D
V
A
S
V
I
V
T
K
L
D
G
H
A
K
G
G
G
A
L
S
A
V
A
A
T
K
S
P
I
I
F
I
G
T
G
E
H
I
D
D
F
E
P
F
K
T
Q
P
F
I
S
K
L
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
71.46
49%
-52
- C7 -
-
1RJ9
2
SRP54_THEAQ
B:
[14-295]
--------------
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
----
E
A
--
R
------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
-
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
G
E
-
S
P
E
--
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
--
P
L
M
G
E
L
A
---------
R
L
K
------
E
V
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
HHSearch
62.44
33%
-12
- C7 -
-
5L3R
3
CFTSY_ARATH
B:
[14-293]
--------------------------------
F
W
N
L
A
E
T
D
R
V
L
D
E
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
K
L
K
S
----
G
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
----
K
N
SK
T
E
L
----
Q
L
G
F
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
-
G
T
K
V
L
M
A
A
G
-
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
-
I
V
-
V
A
E
G
D
K
A
K
A
-
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
--
S
L
M
E
E
L
I
---------
A
C
K
------
K
A
V
G
K
I
VSG
A
------
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
-
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96
HHSearch
60.21
34%
37
- C7 -
-
3E70
2
?
C:
[7-324]
-
M
F
G
K
L
R
E
K
L
K
S
F
V
K
R
V
E
E
E
VEKEEEEVILT
V
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
----
S
R
--
R
I
D
LIEE
I
R
K
A
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
-
G
F
S
V
V
I
A
A
S
-
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
-
K
H
S
Y
G
-
A
D
P
-
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
--
N
L
M
D
E
M
K
---------
K
I
A
------
R
V
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
-
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
60.10
35%
-13
- C7 -
-
3E70
2
?
C:
[46-324]
--------------------------------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
SRRI
D
L
--
I
E
E
----
I
R
K
A
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
-
G
F
S
V
V
I
A
A
S
-
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
-
K
H
S
Y
G
-
A
D
P
-
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
--
N
L
M
D
E
M
K
---------
K
I
A
------
R
V
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
-
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
59.03
39%
-59
- C7 -
-
1VMA
1
?
B:
[101-304]
----------------------------------------------------------------------------------------------------------------------
P
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
-
K
M
F
V
D
E
G
K
S
V
V
L
A
A
A
-
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
-
V
I
-
S
H
S
E
G
-
A
D
P
-
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
--
N
L
M
E
E
L
R
---------
K
V
H
------
R
V
V
------
K
KKIPDA
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
-
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
54.52
40%
-34
- C7 -
-
5L3R
3
CFTSY_ARATH
B:
[91-292]
-------------------------------------------------------------------------------------------------------------------------
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
-
G
T
K
V
L
M
A
A
G
-
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
V
-
A
E
G
D
K
-
A
K
A
-
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
--
S
L
M
E
E
L
I
---------
A
C
K
K
A
V
G
K
I
V
S
G
------
A
------
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
-
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
54.18
40%
-34
- C7 -
-
5L3R
3
CFTSY_ARATH
D:
[91-292]
-------------------------------------------------------------------------------------------------------------------------
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
-
G
T
K
V
L
M
A
A
G
-
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
V
-
A
E
G
D
K
-
A
K
A
-
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
--
S
L
M
E
E
L
I
---------
A
C
K
KAVGKI
V
S
G
------
A
------
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
-
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
54.03
34%
-12
- C7 -
-
4C7O
3
FTSY_ECOLI
D:
[19-267]
----------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
Q
----
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
----
V
D
--
E
P
L
----
N
V
E
G
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
--
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
-
A
Q
H
T
G
-
A
D
S
-
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
--
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
------
A
---------------
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
-
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
52.54
34%
-10
- C7 -
-
4C7O
2
FTSY_ECOLI
B:
[19-267]
----------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
Q
----
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
----
V
D
--
E
P
L
----
N
V
E
G
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
--
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
-
A
Q
H
T
G
-
A
D
S
-
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
--
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
------
A
---------------
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
-
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
47.15
31%
-23
- C7 -
-
1OKK
6
FTSY_THEAQ
D:
[114-301]
--------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
-
Q
G
P
E
G
-
T
D
P
-
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
--
N
L
M
E
E
L
K
---------
K
V
K
R-----
A
I
A
KADPE-
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
46.81
31%
-25
- C7 -
-
1RJ9
2
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
-
Q
G
P
E
G
-
T
D
S
-
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
--
N
L
M
E
E
L
K
---------
K
V
K
R
-----
A
I
A
K
A
DPE-
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
46.48
31%
-22
- C7 -
-
2J7P
1
FTSY_THEAQ
E:
[94-281]
--------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
-
Q
G
P
E
G
-
T
D
P
-
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
--
N
L
M
E
E
L
K
---------
K
V
K
R-----
A
I
A
KADPE-
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
46.36
31%
-22
- C7 -
-
2J7P
4
FTSY_THEAQ
D:
[94-281]
--------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
-
Q
G
P
E
G
-
T
D
P
-
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
--
N
L
M
E
E
L
K
---------
K
V
K
R
-----
A
I
A
K
A
DPE-
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
46.31
31%
-35
- C7 -
-
2IYL
1
FTSY_THEAQ
D:
[95-282]
--------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
-
Q
G
P
E
G
-
T
D
P
-
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
--
N
L
M
E
E
L
K
---------
K
V
K
R-----
A
I
A
KADPE-
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
45.03
31%
-25
- C7 -
-
2Q9B
5
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
-
Q
G
P
E
G
-
T
D
P
-
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
--
N
L
M
E
E
L
K
---------
K
V
K
R
-----
A
I
A
K
A
DPE-
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------