@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1191: (2018-01-07 )
MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGESGCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMIFQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPHQFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILITHDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLHVIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFEDKEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIVGESGSGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDPYASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEFSGGQRQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGVVKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKENEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE
Atome Classification :
(20 SA)
----------------------------------------------------------------.........10........20........30.------.......40........50......-..60........70........80........90........100.......110.......120.....-..--130......-----.140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.-......250.......260--.......---..270--.--.----------..--------.----------------..280--....----..----...-290---------------------------------.......-----------.300...--.--------.....--------------------------------310-----------.-----------..-------------------.-.---.-----------.320------.--------------------------.......330----.-----------------.-------------------.-----...---..340-----.........350.......360.......370.......380.......390.......400.......410.......420-.........430........440--------------....-----------.-..450-...-------------..-..------------.460.....-------..470.....--------------------------...480.......490.----------.----------.-....500.......510.......520.......530.......540.......550.......560.......570......--.580.......590.......600.......610.......620.......630.......640.......650.......660
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------MNQ
T
V
L
D
V
K
NL
K
T
E
FITDKKAF
P
I
I
KDV
N
F
T
L
------ER
G
K
V
L
G
I
VGESGCG
K
S
V
T
V
N
T
V
L
N
-LLPKNGRIAE
G
E
I
T
Y
FDEDKPI
E
L
Q
K
L
K
Q
Y
G
K
E
F
R
K
LRGEN
I
S
M
I
FQD
P
M
S
AL
N
P
V
Y
T
I
G
N
Q
I
T
E
V
L
H
E
H-YD--I
S
K
E
E
A
N
K
R
-----
A
I
E
M
L
E
K
LGI
H
N
A
A
E
R
MNDYPHQFSGG
Q
R
Q
R
I
V
I
A
I
A
M
VCNP
D
I
L
I
ADEPT
T
A
L
D
V
T
I
Q
A
Q
I
L
D
L
L
D
D
L
R
K
EHG
T
S
I
I
L
I
TH
D
L
G
V
I
A
Q
I
A
D
E
V
A
V
M
YAG
E
V
V
EV-
G
T
V
A
Q
I
FDQPKH
P
Y
T
R
S
----
L
L
R
SIP
N
---
P
E
N
MD--K--
K
----------
L
H
--------
V
----------------IQG----SVP
S
----
I
S
----
E
I
S
-
E
K
----------------------------------
G
C
R
F
A
NR-----------IP--WLE--K--------EHHEE--------------------------------EPQ-----------L-----------HD-------------------L-G---D-----------G
H
F
-------
V
--------------------------
R
C
S
C
Y
K
H
FF-----F-----------------E-------------------D-----K
E
E
---
E
T
L
-------
A
E
K
HVG
N
V
V
L
E
V
K
N
I
K
K
YYY
P
K
K
Q
L
F
K
PLG
S
P
L
K
A
LDD
V
S
L
E
LRKG
T
T
I
G
I
VGESGS
G
K
S
T
I
A
K
S
L
M
K
L
HDITD
G
E
I
N
I
D
---LNGKTQ
N
I
YGI-KRKE
D
L
D
F
R
K
K
--------------
V
Q
M
V
-----------
F
-QDPY--ASL-------------N
P
-
T
K
------------
K
I
Y
N
SFDE
P
-------
M
I
V
-HNIG
N
K
--------------------------
E
E
R
F
E
R
M
K
E
A
L
K
M
VNV
P
----------
V
----------
E
-
Y
L
E
RYPHEFSGG
Q
R
Q
R
L
C
I
A
R
A
LCMKP
E
I
L
I
LDEPV
S
A
L
D
L
S
V
Q
A
Q
V
L
N
Y
L
V
E
IQNKE
D
L
T
Y
V
F
I
SHDL
G
V
V
K
Y
M
C
D
Y
L
Y
V
IH--K
G
R
I
V
EAGSREDIYNN
P
M
H
I
Y
T
K
K
L
L
A
AIPE
V
D
Y
H
F
K
E
A
L
A
TKRKEN
E
V
E
F
K
A
Q
Y
H
E
F
YDEDG
R
A
YDLKQVSPT
H
F
V
A
LKPE
96
HHSearch
75.83
27%
-10
- C2 -
-
5KO2
-
MDR1A_MOUSE
B:
[386-1227]
-------------------------------------------------------------------
G
N
L
E
F
K
N
I
H
F
S
Y
P
S
R
-
K
E
V
Q
I
L
K
G
L
N
L
K
V
------
K
S
G
Q
T
V
A
L
V
G
N
S
G
C
G
K
S
T
T
V
Q
L
M
Q
R
-
L
Y
D
P
L
----
D
G
M
V
S
I
D
G
Q
D
----
I
R
T
I
-----
N
V
-
R
Y
L
R
E
I
I
G
V
V
S
Q
E
P
V
L
--
F
-
A
T
T
I
A
E
N
I
R
Y
G
R
E
D
V
-
T
---
M
--
D
E
I
E
K
A
VKEAN
A
Y
D
F
I
M
K
L
P
H
Q
-
F
D
T
L
V
G
E
R
G
A
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
Q
A
T
S
A
L
D
T
E
S
E
A
V
V
Q
A
A
L
D
K
A
R
--
E
G
R
T
T
I
V
I
A
H
R
L
S
T
V
R
-
N
A
D
V
I
A
G
F
D
G
G
V
I
V
E
Q
-
G
N
H
D
E
L
M
R
E
K
G
I
Y
F
K
L
V
MTQT-------------
D
V
PP
A
SF
W
RI--------
L
K
--------
L
NSTEWPYFVVGIFCAI
I
N
G
GLQP
A
F
S
V
IFSK
V
V
GVFT
N
G
G
P
P
E
TQRQNSNLFSLLFLILGIISFITFFLQGFTFGKA
G
E
I
L
T
K
R
LRYMVFKSMLR
Q
D
VS
W
F
D
DP
K
NTTGALTT
R
L
A
N
D
AAQVKGATGSRLAVIFQNIANLGTGIIISLIY
G
W
Q
LTLLLLAIVPI
I
AIAGVVEMKML
S
G
QALKDKKELEGSGKIATEA
I
-
E
NFR
T
VVSLTREQKFE
T
M
Y
AQSLQIP
Y
RNAMKKAHVFGITFSFTQAMMYFSYA
A
C
F
R
F
G
A
Y
L
VTQQL
M
TFENVLLVFSAIVFGAM
A
VGQVSSFAPDYAKATVSAS
H
IIRII
E
K
T
---
P
E
I
DSYSTQG
L
K
P
N
M
L
E
G
N
V
Q
F
S
G
V
V
F
N
Y
P
T
R
--------
P
S
I
P
V
L
Q
G
L
S
L
E
V
K
K
G
Q
T
L
A
L
V
G
S
S
G
C
G
K
S
T
V
V
Q
L
L
E
R
F
Y
D
P
M
A
G
S
V
F
L
D
-----
G
--
K
E
I
K
Q
L
----
N
V
Q
W
L
R
A
Q
--------------
L
G
I
V
-----------
S
-
Q
E
P
I
----
L
-------------
F
--
D
C
------------
S
I
A
E
N
I
A
Y
G
-------
D
N
S
-
R
V
V
S
-------------------------------
Y
E
E
I
V
R
A
A
K
E
A
N
I
H
QFIDSLPDKY
N
----------
T
-
R
V
G
D
K
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
Q
P
H
I
L
L
L
D
Q
A
T
S
A
L
D
T
E
S
E
K
V
V
Q
E
A
L
D
K
A
R
--
E
G
R
T
C
I
V
I
A
H
R
L
S
T
I
Q
N
-
A
D
L
I
V
V
I
Q
--
N
G
K
V
K
E
H
G
T
H
Q
Q
L
L
A
Q
K
G
----------------------------------------------------------------
95
HHSearch
75.26
26%
-11
- C2 -
-
5KO2
-
MDR1A_MOUSE
A:
[386-1226]
-------------------------------------------------------------------
G
N
L
E
F
K
N
I
H
F
S
Y
P
S
R
-
K
E
V
Q
I
L
K
G
L
N
L
K
V
------
K
S
G
Q
T
V
A
L
V
G
N
S
G
C
G
K
S
T
T
V
Q
L
M
Q
R
-
L
Y
D
P
L
----
D
G
M
V
S
I
D
G
Q
D
----
I
R
T
I
-----
N
V
-
R
Y
L
R
E
I
I
G
V
V
S
Q
E
P
V
L
--
F
-
A
T
T
I
A
E
N
I
R
Y
G
R
E
D
V
-
T
M
D
E
I
E
K
A
V
K
E
A
N
-----
A
Y
D
F
I
M
K
L
P
H
Q
-
F
D
T
L
V
G
E
R
G
A
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
Q
A
T
S
A
L
D
T
E
S
E
A
V
V
Q
A
A
L
D
K
A
R
--
E
G
R
T
T
I
V
I
A
H
R
L
S
T
V
R
-
N
A
D
V
I
A
G
F
D
G
G
V
I
V
E
Q
-
G
N
H
D
E
L
M
R
E
K
G
I
Y
F
K
L
V
M
T
Q
T-------------
D
V
P
P
A
S
F
W
R
I
L
K
L
N
STE
W
P
Y
F
V
V
G
I
F
C
A
I
----------------
I
N
G
G
L
Q
P
A
F
S
V
I
F
S
K
V
V
G
V
F
T
N
G
G
P
P
E
T
Q
R
Q
N
S
N
L
F
S
L
L
F
L
I
L
G
I
I
S
F
I
T
F
F
L
Q
G
F
T
F
G
K
A
G
E
I
L
T
K
R
L
R
Y
M
V
F
K
S
M
L
R
Q
D
V
S
W
F
D
DP
K
NT
T
G
A
L
T
T
R
L
A
N
D
AAQ
V
K
G
A
T
G
S
R
L
A
V
I
F
Q
N
I
A
N
L
G
T
G
I
I
I
S
L
I
Y
G
W
Q
L
T
L
L
L
L
A
I
V
P
I
I
A
I
A
G
V
V
E
M
K
M
L
S
G
Q
A
L
K
D
K
K
E
L
E
G
S
G
K
I
A
T
E
A
I
-
E
N
F
R
T
V
V
S
L
TR
E
Q
K
F
E
T
M
Y
A
Q
S
L
Q
I
P
Y
R
N
A
M
K
K
A
H
V
F
G
I
T
F
S
F
T
Q
A
M
M
Y
F
S
Y
A
A
C
F
R
F
G
A
Y
L
V
T
Q
QL
M
T
F
E
N
V
L
L
V
F
S
A
I
V
F
G
A
M
A
V
G
Q
V
S
S
F
APD
Y
A
K
A
T
V
S
A
S
H
I
I
---
R
I
I
E
KT
P
E
I
DSYSTQG
L
K
P
N
M
L
E
G
N
V
Q
F
S
G
V
V
F
N
Y
P
T
R
--------
P
S
I
P
V
L
Q
G
L
S
L
E
V
K
K
G
Q
T
L
A
L
V
G
S
S
G
C
G
K
S
T
V
V
Q
L
L
E
R
F
Y
D
P
M
A
G
S
V
F
L
D
-----
G
--
K
E
I
K
Q
L
----
N
V
Q
W
L
R
A
Q
--------------
L
G
I
V
-----------
S
-
Q
E
P
I
----
L
-------------
F
--
D
C
------------
S
I
A
E
N
I
A
Y
G
-------
D
N
S
-
R
V
V
S
-------------------------------
Y
E
E
I
V
R
A
A
K
E
A
N
I
H
----------
Q
F
I
D
S
LPDKYN
T
-
R
V
G
D
K
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
Q
P
H
I
L
L
L
D
Q
A
T
S
A
L
D
T
E
S
E
K
V
V
Q
E
A
L
D
K
A
R
--
E
G
R
T
C
I
V
I
A
H
R
L
S
T
I
Q
N
-
A
D
L
I
V
V
I
Q
--
N
G
K
V
K
E
H
G
T
H
Q
Q
L
L
A
Q
K
-----------------------------------------------------------------
115
HHSearch
72.15
31%
-144
- C2 -
-
3DHW
-
METN_ECOLI
C:
[1-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
-------
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
-----
G
--
Q
E
L
T
T
L
-
S
E
S
E
L
T
K
A
R
R
Q
--------------
I
G
M
I
-----------
F
-
Q
H
F
----
N
L
-------------
L
S
-
S
R
------------
T
V
F
G
N
V
A
L
P
-------
L
E
L
-
D
N
T
P
-
K
--------------------------
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
----------
D
------------
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
--
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
--------------------------------------------------
24
PsiBlast_CBE
67.03
32%
-151
- C2 -
-
3TUI
1
METN_ECOLI
H:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
67.00
32%
-142
- C2 -
-
3TUI
1
METN_ECOLI
C:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
66.69
32%
-150
- C2 -
-
3TUZ
1
METN_ECOLI
C:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
66.40
32%
-140
- C2 -
-
3TUZ
1
METN_ECOLI
G:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
66.18
32%
-138
- C2 -
-
3TUI
1
METN_ECOLI
D:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
66.02
34%
-62
- C2 -
-
4FWI
2
?
B:
[4-320]
--------------------------------------------------------------------
I
I
R
V
E
D
L
R
A
V
Y
L
V
R
E
G
T
I
K
A
A
D
G
I
S
L
D
I
------
L
E
N
S
V
T
A
I
V
G
E
S
A
S
G
K
S
T
I
I
E
A
M
T
K
-
T
L
P
P
N
G
R
I
L
S
G
R
V
L
Y
K
G
K
D
L
------
L
T
M
R
E
E
E
L
R
K
I
R
W
K
E
I
A
L
V
P
Q
A
A
Q
Q
S
L
N
P
T
M
K
V
I
E
H
F
K
D
T
V
E
A
H
G
V
R
--
W
S
H
S
E
L
I
E
K
-----
A
S
E
K
L
R
M
V
R
L
-
N
P
E
A
V
L
N
S
Y
P
L
Q
L
S
G
G
M
K
Q
R
V
L
I
A
L
A
L
L
L
D
P
V
V
L
I
L
D
E
P
T
S
A
L
D
V
L
T
Q
A
H
I
I
Q
L
L
K
E
L
K
K
M
L
K
I
T
L
I
F
V
T
H
D
I
A
V
A
A
E
L
A
D
K
V
A
V
I
Y
G
G
N
L
V
E
Y
-
N
S
T
F
Q
I
F
K
N
P
L
H
P
Y
T
R
G
----
L
I
N
S
I
M
-----------------------------------
P
----------------
I
P
G
----
D
P
P
S
----
L
L
----
N
-
P
-
P
S
----------------------------------
G
C
R
F
H
P
R
-----------
C
E
--
Y
A
M
--
E
--------
I
C
K
K
E
--------------------------------
K
P
K
-----------
W
-----------
I
R
-------------------
L
D
G
---
E
-----------
A
H
--------
V
--------------------------
A
C
H
L
Y
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
65.78
32%
-150
- C2 -
-
3TUZ
1
METN_ECOLI
H:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
65.15
32%
-142
- C2 -
-
3TUZ
1
METN_ECOLI
D:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
64.37
32%
-139
- C2 -
-
3TUI
1
METN_ECOLI
G:
[24-281]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
64.00
31%
-150
- C2 -
-
3TUJ
-
METN_ECOLI
C:
[2-258]
---------------------------------------------------------------------
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112
HHSearch
63.31
24%
-95
- C3 -
-
1YQT
2
?
A:
[24-485]
-----------------------------------------------------------------------
E
E
D
C
V
H
R
Y
G
V
----
N
A
F
V
L
Y
R
L
P
V
V
------
K
E
G
M
V
V
G
I
V
G
P
N
G
T
G
K
S
T
A
V
K
I
L
A
G
-
Q
L
I
P
N
L
--
C
G
D
N
D
S
W
D
G
V
I
R
A
F
R
G
N
E
L
---
Q
N
Y
F
E
K
L
K
N
G
E
I
R
P
V
V
K
P
Q
Y
V
D
L
I
P
K
A
V
-
K
G
K
V
I
E
L
---------
L
K
K
A
D
E
T
G
K
-----
L
E
E
V
V
K
A
L
E
L
E
---
N
V
L
E
R
E
I
Q
H
L
S
G
G
E
L
Q
R
V
A
I
A
A
A
L
L
R
N
A
T
F
Y
F
F
D
E
P
S
S
Y
L
D
I
R
Q
R
L
N
A
A
R
A
I
R
R
L
S
E
-
E
G
K
S
V
L
V
V
E
H
D
L
A
V
L
D
Y
L
S
D
-
I
I
H
V
V
Y
G
E
P
G
V
Y
-
G
I
F
S
Q
----
P
K
G
T
R
-
N
--------
G
I
N
E
---
F
-----------------------------------------------
L
R
G
----
Y
L
K
D
---------------
E
----------------------------------
N
V
R
F
R
P
Y
-----------
E
I
----------------
K
F
T
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
---
E
R
V
---------
E
I
E
R
E
T
L
V
T
Y
P
R
L
V
K
D
Y
------------
G
S
F
R
L
E
V
E
P
G
E
I
K
K
G
E
V
I
G
I
V
G
P
N
G
I
G
K
T
T
F
V
K
M
L
A
G
V
E
E
P
T
E
G
K
I
E
W
D
-----
L
-------------------
T
--------------
V
A
Y
K
-----------
P
-
Q
Y
I
K
----
A
-------------
D
Y
-
E
G
------------
T
V
Y
E
L
L
S
K
I
-------
D
A
S
-
K
L
-------------------------------
N
S
N
F
Y
K
T
E
L
L
K
P
L
G
I
I
----------
D
------------
L
Y
D
R
E
V
N
E
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
R
D
A
D
I
Y
L
L
D
E
P
S
A
Y
L
D
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
R
L
M
V
F
E
--
G
E
P
G
K
Y
G
R
A
-------------------------------------------------------------------------
86
Fugue
62.18
21%
40
* C3 *
-
3J16
3
RLI1_YEAST
B:
[1-608]
MS
D
K
N
S
R
I
A
I
V
S
ADKCKPKKCRQ
E
C
K
R
S
C
P
V
V
K
T
GKLC
I
E
V
T
PTSK
I
A
F
I
S
EILCIGCG
I
C
V
K
K
C
P
F
D
A
I
Q
I
I
N
L
P
T
N
L
--
E
A
H
V
T
H
R
Y
S
A
N
S
F
K
L
H
R
L
P
T
P
R
P
G
Q
V
L
G
L
V
G
T
N
G
I
G
K
S
T
A
L
K
I
L
A
G
K
Q
K
P
N
L
G
R
F
D
D
P
P
----
E
W
Q
E
I
I
K
Y
F
R
G
S
E
L
Q
N
Y
F
T
K
M
L
E
D
D
I
K
A
I
I
K
P
Q
Y
V
D
N
I
P
R
A
I
K
G
P
--
V
Q
K
V
G
E
L
-
L
K
--
L
R
M
E
K
S
P
E
D
-----
V
K
R
Y
I
K
I
L
Q
L
E
N
V
L
K
R
D
---
I
E
K
L
S
G
G
E
L
Q
R
F
A
I
G
M
S
C
V
Q
E
A
D
V
Y
M
F
D
E
P
S
S
Y
L
D
V
K
Q
R
L
N
A
A
Q
I
I
R
S
L
L
A
P
-
T
K
Y
V
I
C
V
E
H
D
L
S
V
L
D
Y
L
S
D
F
V
C
I
I
Y
-
G
V
P
S
V
Y
-
G
V
V
T
L
--------------------------
P
A
S
V
R
--
E
--
G
----------
I
N
--------
I
----------------
F
L
D
----
G
-------------
H
I
P
-
A
E
----------------------------------
N
L
R
F
R
T
E
-----------
A
L
--
Q
F
R
--
I
--------
A
D
A
T
E
--------------------------------
D
L
Q
-----------
N
-----------
D
S
----------------------------------------------------------------------------------------
A
-----------------
S
-------------------
R
-----
A
F
S
---
Y
P
S
-------
L
K
K
T
Q
G
D
F
V
L
N
V
E
--------------------------
E
G
E
F
S
D
S
E
I
L
V
M
M
G
E
N
G
T
G
K
T
T
L
I
K
L
L
A
G
A
L
K
P
D
E
G
Q
D
I
P
K
---
L
N
V
S
M
K
------
P
Q
K
I
A
P
K
F
P
G
T
--------------
V
R
Q
L
-----------
F
-
F
K
K
I
--
R
G
Q
-------------
F
L
-
N
P
------------
Q
F
Q
T
D
V
V
K
P
-------
L
R
I
-
D
D
I
----------------------------------------------------------------------
I
D
Q
E
V
Q
H
L
S
G
G
E
L
Q
R
V
A
I
V
L
A
L
G
I
P
A
D
I
Y
L
I
D
E
P
S
A
Y
L
D
S
E
Q
R
I
I
C
S
K
V
I
R
R
F
I
L
H
N
K
K
T
A
F
I
V
E
H
D
F
I
M
A
T
Y
L
A
D
K
V
I
V
F
E
G
I
P
S
K
N
A
H
A
R
A
P
E
S
-
L
L
T
G
C
N
R
F
L
K
N
L
N
V
T
F
R
R
D
P
N
S
F
R
P
R
I
N
K
L
D
S
Q
M
D
K
E
Q
K
S
S
G
N
Y
F
F
L
D
N
T
G
I
-----------------
80
Fugue
62.05
25%
-127
- C2 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
-------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
R
P
T
---
E
G
S
V
L
V
D
G
Q
E
----
L
T
T
L
S
--
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
F
--
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
--
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
G
D
---
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
---
L
D
I
P
E
--
D
--
Y
----------
Q
E
--------
R
----------------
L
Q
A
----
E
P
F
T
----
D
C
----
V
----
P
----------------------------------
M
L
R
L
E
F
T
-----------
G
Q
--
S
V
D
--
A
--------
P
L
L
S
E
--------------------------------
T
A
R
-----------
R
-----------
F
N
-------------------
V
------------------------------------------------------------
N
N
N
-----
I
-----------------
I
-------------------
S
-----
A
Q
M
---
D
Y
A
-------
G
G
V
K
F
G
I
M
L
T
E
M
H
G
T
Q
Q
D
T
Q
A
A
I
A
W
L
Q
E
H
H
V
K
V
E
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
60.86
32%
-136
- C2 -
-
3DHW
-
METN_ECOLI
C:
[1-258]
--------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
------
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-
N
-
L
L
E
---
R
P
T
E
G
S
V
L
V
D
G
Q
----
E
L
T
T
L
S
E
--
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
-
D
N
--
T
P
K
D
E
V
K
R
R
-----
V
T
E
L
L
S
L
V
G
L
---
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
-
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
LDI
P
E
D
Y
Q
--
E
--
R
----------
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
HHSearch
58.61
20%
-49
- C1 -
-
2IW3
1
EF3A_YEAST
A:
[434-978]
---------------------------------------------------------------------
E
D
L
C
N
C
E
F
S
L
A
Y
G
--
A
K
I
L
L
N
K
T
Q
L
R
L
------
K
R
A
R
R
Y
G
I
C
G
P
N
G
C
G
K
S
T
L
M
R
A
I
A
N
-
G
Q
V
D
------
G
F
P
T
Q
E
E
C
---------------------
R
T
V
-
Y
V
E
H
D
I
D
-
G
T
H
S
D
T
S
V
L
D
F
V
F
E
S
G
V
G
-----------
T
K
E
A
-----
I
K
D
K
L
I
E
F
G
F
T
D
--
E
M
I
A
M
P
I
S
A
L
S
G
G
W
K
M
K
L
A
L
A
R
A
V
L
R
N
A
D
I
L
L
L
D
E
P
T
N
H
L
D
T
V
N
V
A
W
L
V
N
Y
L
N
T
----
C
G
I
T
S
I
T
I
S
H
D
S
V
F
L
D
N
V
C
E
Y
I
I
N
Y
E
G
L
K
L
R
K
Y
K
G
N
F
T
E
F
V
K
K
C
----------------
P
A
---
A
K
A
------------------
Y
E
--------
E
----------------
L
S
N
----
T
D
L
-----------------------------------------------------
E
F
---------------
K
--
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-----
P
G
----
Y
L
E
-------
G
V
K
T
K
Q
K
A
I
V
K
V
T
N
M
E
F
Q
Y
P
G
T
---------
S
K
P
Q
I
T
D
I
N
F
Q
C
S
L
S
S
R
I
A
V
I
G
P
N
G
A
G
K
S
T
L
I
N
V
L
T
G
E
L
L
P
T
S
G
E
V
Y
T
H
-----
E
--
N
C
R
I
A
Y
I
K
Q
H
A
F
A
H
I
E
S
H
LDKT
P
S
E
Y
I
Q
W
R
F
Q
T
G
E
D
RETMDRANRQI
N
E
N
D
A
E
A
M
N
K
I
F
K
I
EG
T
P
R
R
IAGI
H
S
-
R
R
K
F
KN
T
Y
E
Y
E
C
S
F
L
L
G
E
N
I
G
M
K
S
E
R
W
V
P
M
M
S
V
D
N
A
W
I
P
R
GELVESH
S
K
M
V
A
E
V
D
M
K
E
A
L
A
S
GQFR
P
L
T
R
K
E
I
E
E
H
C
S
M
L
G
L
D
----------
P
----------
E
I
V
S
H
S
R
I
R
G
L
S
G
G
Q
K
V
K
L
V
L
A
A
G
T
W
Q
R
P
H
L
I
V
L
D
E
P
T
N
Y
L
D
R
D
S
L
G
A
L
S
K
A
L
K
E
F
----
E
G
G
V
I
I
I
T
H
S
A
E
F
T
K
N
L
T
E
E
V
W
A
V
K
--
D
G
R
M
T
P
----------------------------------------------------------------------------
114
HHSearch
57.88
25%
-141
* C2 *
-
3RLF
2
MALK_ECOLI
A:
[3-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
Q
L
Q
N
V
T
K
A
W
G
-----------
E
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
-----
E
--
K
R
M
N
D
T
------
P
P
A
E
R
G
--------------
V
G
M
V
-----------
F
-
Q
S
Y
----
A
L
-------------
Y
P
-
H
L
------------
S
V
A
E
N
M
S
F
G
-------
L
K
L
-
A
G
A
K
K
---------------------------
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
----------
H
------------
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
--
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
------------------------------------------------------
41
PsiBlast_CBE
57.74
36%
-30
- C2 -
-
4YMU
1
?
A:
[7-239]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
K
N
F
G
S
-
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
GVK
I
N
N
G
K
V
N
I
N
K
V
---------
R
Q
K
--------------
V
G
M
V
-----------
F
-
Q
--
H
--
F
N
L
-------------
F
P
H
L
T
------------
A
I
E
N
I
T
L
A
P
-------
V
K
V
-
K
K
M
-
N
K
--------------------------
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
-----------
L
----------
D
-
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
--
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
-----------------------------------------------------