@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1201: (2018-01-07 )
MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNSQVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSFLVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVVLISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDSTILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSYIKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIISIAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYYSLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS
Atome Classification :
(18 SA)
------------------------------------------------------------------------------------------------------.....------....10-------------------......-..20-......------.---..30.....-------------...40--------------.......-------------.-50--------..-...---------------....-----------60----..-----------.......---70.------.......80........90-----------....--------.....100..----------------....-----------.110-----------.......120----------.-------------------------...-------------...130.......---140--........150.------------------------------------......160----..--....--...170.......180..--------....-----.190.......200-..---------------------------....------...210....---------....220.....---------------------..230---....------....240..----.....250.......-260-..-----......270.-....-----------..280....---...290.......---.300.-.-.....310.......320-----.......------------------------------------.330--........340..------..-...350.......360.......370--------.....----....380------..------.......390......-----------.400----....-------------....--410---........----420..-------.....430.......--------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------M
L
R
L
V
------
Y
Y
Q
F
LH-------------------NK
K
Q
WL-GV
S
--
P
V
I
F
V
S
------
S
---
L
V
M
G
L
AV
N
G
-------------
V
I
N
VE--------------NN
S
Q
V
F
V
-------------G-L---------PD-PK
P
---------------
I
F
M
F
-----------
P
-----
I
V
-----------FG
G
V
T
L
F
---
F
V
L
------
S
N
I
I
N
M
L
V
E
I
F
RD
D
Y
E
L
L
------------
E
V
LG--------AS
R
L
Q
L
S
F
LV----------------GG
Q
I
-----------
F
I
I
S
-----------
S
I
I
S
F
I
A
Y
L
C
----------
S
-------------------------
I
F
V-------------TS
N
Y
Y
Y
F
L
Q
Y
F
F
G---EN---ILPD
I
Q
F
QTS
A
V
------------------------------------
G
C
I
I
T
V
V
------
L
I
--
S
F
L
A
--
F
L
S
G
C
F
Y
T
F
K
K
I
RNR
K
S
S
--------
K
I
R
H
-----
V
L
S
I
V
K
R
I
L
L
L
A
---
G
F
---------------------------
S
V
I
W
------
L
L
S
L
Q
-
Q
I
FQ---------DS
T
I
L
A
K
A
Q
I
I
F
---------------------
N
I
V
I
----
L
D
I
V
------
I
I
YQL
S
P
F
I
----
Q
S
C
F
I
K
L
L
S
I
I
I
FRN-
N
F
--
M
F
-----
I
VSKW
N
L
L
Y
C
-
K
S
Y
I
-----------
K
S
I
S
A
A
I
T
G
---
A
I
L
L
-
I
S
S
F
Q
M
I
S
---
Q
N
I
L
S
-
Q
-FQDDSD
L
E
L
K
V
A
F
I
V
YV------G
A
P
I
L
I
V
------------------------------------
L
A
N
---
I
I
S
I
A
F
L
S
S
H
Q
E
R
------
I
E
-
I
Q
Q
F
E
I
LGTSN
Y
Q
M
V
K
I
KVG
E
A
I
F
----------
L
T
F
V
T
----
S
L
I
A
F
--------
L
L
------
N
I
K
I
M
A
L
I
Y
Y
S
L
E
D
I
L
-----------ID
D
-----
M
N
L
L
-------------
G
L
I
L
--
P
N
----
F
I
V
S
I
I
L
F
----
I
L
I
F
I-------TKS
S
Y
F
I
F
KN
A
K
IIS--------------------------------
16
Fugue
74.11
18%
-98
- C2 -
-
3VSM
1
OE66_NPVAC
A:
[27-659]
-------------------------------------------------------------------------------------------N
I
Q
E
L
Q
N
F
E
R
W
F
K
N
N
L
------
S
Y
S
F
S
Q
KA
E
K
V
V
NPN
R
N
W
N
DNTVFD
N
L
S
P
W
T
-
S
V
P
--
D
F
G
T
V
C
------
H
---
T
L
I
G
Y
C
V
R
Y
N
NTSDTLYQN
P
E
L
A
Y
N
L
I
--------------
N
G
L
R
I
I
C
-------------
S
K
L
---------
P
D
-
P
P
P
HQQAPWGPVADWYHF
T
I
T
M
-----------
P
-----
E
V
-----------
F
M
N
I
T
I
V
---
L
N
E
------
T
Q
H
Y
D
E
A
A
S
L
T
R
Y
W
L
G
L
Y
LPTAVNSMG
W
H
R
T
A
G
N
--------
S
M
R
M
G
V
P
Y
T
Y
----------------
S
Q
M
L
R
GYS
L
A
Q
I
R
Q
E
Q
G
I
Q
-----------
E
I
L
N
T
I
A
F
P
Y
VTQGNGLHVD
S
-------------------------
I
Y
I
D
HIDVRAY
G
Y
L
I
N
S
Y
F
T
F
A
Y
Y
T
Y
Y
F
G
---
D
E
---
V
I
N
T
V
G
L
T
R
A
I
E
N
VGSPE------------------------------
G
V
V
V
P
G
V
------
M
S
--
R
N
G
T
--
L
Y
S
N
V
I
G
N
F
I
T
Y
P
L
A
V
H
S
ADYS
K
V
L
T
K
L
S
K
T
Y
Y
G
S
V
V
G
V
T
N
R
L
A
Y
Y
E
---
S
D
PTNNIQ---------------------
A
P
L
W
------
T
M
A
-
R
-
R
I
W
N
RRGRI
I
N
Y
N
A
N
T
V
S
F
E
S
G
I
I
L
QSLNG
I
M
R
I
P
S
GTT
S
T
Q
S
F
R
P
T
I
G
Q
----
T
A
I
A
K
T
DT
A
G
A
I
L
V
Y
A
K
F
A
----
E
M
N
N
L
Q
F
K
S
C
T
L
F
Y
D
-
H
G
--
M
F
-----
Q
L
Y
Y
N
I
G
V
E
P
-
N
S
L
N
-----------
N
T
-----
N
G
---
R
V
I
V
-
L
S
R
D
T
S
V
N
TND
L
S
F
E
A
-
Q
-
R
I
N
N
N
N
S
S
E
G
T
T
F
N
G
V
V
------
C
H
R
V
P
I
T
------------------------------------
N
I
N
---
V
P
S
L
T
V
R
S
P
N
S
S
-------
V
E
-
L
V
E
Q
I
I
----
S
F
Q
T
M
Y
T
A
T
A
S
A
C
Y
----------
K
L
N
V
E
GHSD
S
L
R
A
F
R
V
NSDEN
I
Y
V
------
N
V
G
N
G
V
K
A
L
F
N
Y
P
W
V
M
-----------
V
K
E
-----
N
N
K
V
-------------
S
F
M
S
--
A
N
EDTT
I
P
F
S
V
I
M
N
----
S
F
T
S
I
GEPA
L
Q
Y
S
P
S
N
C
F
V
Y
G
N
G
F
K
L
N
NSTF
D
L
Q
F
I
F
E
I
V-------------------
13
Fugue
73.56
19%
-112
* C7 *
-
5TZJ
1
?
A:
[1-349]
-------------------------------------------------------------------------------------------------------
M
K
F
S
------
V
I
V
P
T
Y
-------------------
N
S
E
K
-----------
Y
I
T
------
E
---
L
L
N
S
L
A
-------------------------------------------------------
K
-
Q
---------
D
F
-
P
K
T
---------------
E
F
E
V
-----------
V
-----
V
V
-----------
D
D
C
S
T
---------------
D
Q
T
L
Q
I
V
E
K
Y
R
N
K
L
N
----------------
L
K
--------
V
S
Q
L
E
T
N
--
S
----------------
G
G
P
G
-----------
K
P
R
N
-----------
V
A
L
K
Q
A
E
G
E
F
----------
V
-------------------------
L
F
V
-------------
D
S
D
D
Y
I
------
N
---
K
E
---
T
L
K
D
A
A
A
F
I
D
E
H
------------------------------------
H
S
--
D
V
L
------
L
I
--
K
-------------
M
K
G
V
N
G
R
G
V
P
--------
Q
--
S
-----
M
F
K
E
T
A
P
E
V
T
L
L
---
N
S
---------------------------
R
I
I
Y
------
T
L
S
P
T
-
K
I
Y
R
----------
T
A
L
L
K
D
N
D
I
Y
F
--------------------------------------------
P
E
E
L
----
K
S
A
E
D
Q
L
F
T
M
K
A
Y
L
N
A
N
R
--
I
S
-----
V
L
S
D
K
A
Y
Y
Y
A
T
K
R
E
G
-----------
E
H
M
S
S
A
Y
V
S
---
P
E
D
F
-
Y
E
V
M
R
L
I
A
---
V
E
I
L
N
-------
A
D
L
E
--------------------
E
A
------------------------------------
H
K
D
---
Q
I
L
A
E
F
L
N
R
H
F
S
F
------
S
R
-
T
N
G
F
S
L
K
V
K
L
E
E
Q
P
Q
W
I
N
-
A
L
G
D
F
----------
I
Q
A
V
P
----
E
R
V
D
A
--------
L
V
------
M
S
K
L
R
P
L
L
H
Y
A
R
A
K
---------------
D
-----
I
D
N
Y
-------------
R
T
V
E
--
E
S
----
Y
R
Q
G
Q
Y
Y
R
----
F
D
I
V
D
-------
G
K
L
N
I
Q
F
N
E
G
E
P
Y
F
E
GID-----------------------------
17
Fugue
72.29
16%
-60
- C7 -
-
5JM8
1
?
A:
[11-574]
TLD
V
A
A
Q
C
F
L
N
S
L
V
R
E
T
KD
W
R
L
T
EYQP
T
Q
L
I
I
P
LGEQ
Q
A
L
H
F
R
V
AYFSPTQH
H
R
F
E
F
P
A
R
L
V
T
A
SG
S
H
P
V
D
F
A
T
L
S
R
L
I
V
D
K
L
Q
H
Q
L
LLP
A
T
S
C
E
T
F
H
Q
R
V
M
E
S
H
A
H
------
T
Q
Q
A
I
D
-------------------
A
R
H
D
W
A
-
A
L
R
E
K
A
L
N
F
G
E
------
A
E
Q
A
L
L
V
G
H
A
F
H
P
-------------
A
P
K
S
H
EPF-----------
N
Q
Q
E
A
E
R
-------------
Y
-
L
---------
P
D
-
F
A
P
---------------
H
F
P
L
-----------
R
-----
W
F
-----------
A
V
N
K
T
Q
I
---
A
G
E
------
S
L
H
L
N
L
Q
Q
R
L
T
R
F
A
A
E
N
A
------------
P
Q
L
L
--------
N
E
L
S
D
N
Q
W
L
F
----------------
P
L
H
P
-----------
W
Q
G
E
-----------
Y
L
L
Q
Q
-
E
W
C
Q
----------
E
-------------------------
L
V
A
-------------
K
G
L
I
K
D
L
G
E
A
--
G
---
A
P
---
W
L
P
T
T
S
S
R
S
L
Y
C
------------------------------------
A
T
S
R
D
M
I
------
K
F
--
S
L
S
V
--
R
L
T
N
S
V
R
T
L
S
V
K
E
V
K
R
G
M
--------
R
L
A
R
-----
L
A
Q
T
D
D
W
Q
T
L
Q
A
R
F
P
T
F
---------------------------
R
V
M
Q
ED
G
W
A
G
L
R
D
L
H
G
N
I
M
Q
---------
E
S
L
F
A
L
R
E
N
L
L
V
---------------------
D
Q
P
Q
----
S
Q
T
N
------
V
L
V
S
L
T
Q
A
A
PDGG
D
S
L
L
V
A
A
V
K
R
L
S
D
R
L
-
G
I
T
A
Q
Q
-----
A
A
H
A
W
V
D
A
Y
C
-
H
Q
V
L
-----------
K
P
L
F
T
A
E
A
D
---
Y
G
L
V
-
L
L
A
H
Q
------
Q
N
I
L
V
-
Q
-
M
L
G
D
L
--------------------
P
V
G
L
I
------------------------------------
Y
R
D
---
C
Q
G
S
A
F
M
P
H
A
A
G
W
------
L
D
T
I
G
E
A
Q
A
E
N
V
F
T
R
E
Q
L
L
R
Y
F
P
Y
Y
L
L
----------
V
N
S
T
F
----
A
V
T
A
A
--------
L
G
A
A
GLDS
E
A
N
L
M
A
R
V
R
T
L
L
A
E
M
R
D
Q
---------
V
T
H
-----
K
T
C
L
-------------
N
Y
V
L
EN
P
Y
----
W
N
V
K
G
N
F
F
----
C
Y
L
N
D
-------
P
S
V
I
Y
F
D
F
A
N
P
L
L
A
Q
--------------------------------
18
Fugue
71.66
15%
-75
- C4 -
-
4IWS
-
FDC_PSEAE
A:
[23-515]
------------------------------------------------------------------------------------------------------
M
N
R
S
A
L
D
F
R
H
-
F
V
D
H
L
R
-------------------
R
Q
G
D
L
V
-
D
V
H
--
T
E
V
-
D
A
------
N
---
L
E
I
G
A
I
T
R
R
-------------
V
Y
E
R
R
--------------
A
P
A
P
L
F
H
-------------
N
-
I
---------
R
D
-
S
L
P
---------------
G
A
R
V
L
G
APAGLRADR
A
-----
R
A
-----------
H
S
R
L
A
L
H
---
F
G
L
PEHSG
P
R
D
I
V
A
M
L
R
A
A
M
R
A
E
P
I
A
P
------------
R
R
L
E
--------
R
G
P
V
Q
E
N
V
W
L
----------------
G
E
Q
V
--------------------------
D
L
T
R
F
P
V
P
L
-------------------------------------
L
H
E
-------------
Q
D
G
G
R
Y
F
G
T
Y
G
F
H
---
V
V
---
Q
T
P
D
G
S
W
D
S
W
S
V
------------------------------------
G
R
L
M
L
V
D
------
R
N
--
T
L
A
G
P
T
I
P
T
Q
H
I
G
I
I
R
E
Q
W
R
R
L
G
K
--------
P
T
P
W
-----
A
M
A
L
-----------
G
A
---------------------------
P
P
A
A
------
L
A
A
A
G
-
M
P
L
P
---------
E
G
V
--
S
E
A
G
Y
V
G
---------------------
A
L
V
G
----
E
P
V
E
------
V
V
R
---
T
Q
T
----
N
G
L
W
V
P
A
N
T
E
I
V
L
E
G
-
E
I
--
S
L
-----
D
E
T
A
L
E
G
P
M
G
-
E
Y
H
G
-----------
Y
S
F
P
I
G
K
P
Q
---
P
L
F
H
-
V
H
A
L
S
F
R
D
---
Q
P
I
L
P
I
C
-
V
A
G
T
P
P
E
E
N
H
T
I
W
G
T
M
I
------
S
A
Q
L
L
D
V
------------------------------------
A
Q
N
A
GL
P
V
D
M
V
W
C
S
Y
E
A
A
T
C
W
A
V
L
S
I
D
-
V
Q
R
L
A
A
L
G
T
D
A
A
A
F
A
A
-
R
V
A
E
T
V
F
----------
G
S
H
A
G
----
H
L
V
P
K
--------
L
I
L
V
G
NDI
D
V
T
E
I
D
Q
V
V
W
A
L
A
T
R
A
HPLHDHFAFPQ
I
R
D
-----
F
P
M
V
PYLD
A
E
D
K
A
R
GSG
G
R
L
V
--
I
N
----
C
L
Y
P
E
Q
F
A
----
G
Q
M
R
A
-------
A
T
A
S
F
R
H
A
Y
P
T
A
L
R
R
R
V
E
E
R
W
SDYGF---------------------
19
Fugue
66.74
17%
-76
- C3 -
-
5AKP
2
BPHY_XANC8
B:
[18-638]
-------------------------------------------------------------------------------------VCAREPIHIPGLIQPY
G
V
L
L
V
I
DPADGR
I
V
Q
A
S
T
-------------------
T
A
A
D
L
L
-
G
V
P
--
M
A
A
L
L
G
MPY---
T
---
Q
V
L
T
L
P
E
A
Q
-------------
P
F
A
V
D
--------------
D
Q
P
Q
H
L
M
-------------
H
-
A
E
V
R
F
PQRAT
P
P
-
A
S
A
---------------
W
V
A
A
-----------
W
-----
H
L
-----------
Y
P
Q
Q
W
L
V
---
E
M
E
------
P
R
D
A
R
L
L
D
V
T
L
R
E
A
M
P
L
L
------------
R
S
V
E
R
DPG
I
A
E
A
A
V
R
V
A
K
G
L
R
S
L
IGFD
R
V
M
I
Y
R
F
D
EEW
N
G
D
I
-----------
I
A
E
A
-----------
R
K
P
E
L
E
A
Y
L
G
----------
L
-------------------------
H
Y
P
-------------
A
S
D
I
P
A
Q
A
R
A
L
Y
L
---
R
N
R
V
R
Q
I
A
D
V
G
Y
Q
P
S
P
I
QPTVHPQLGTPVDLSDVSLRSVS
P
V
H
L
E
Y
L
A
N
M
GVT
A
T
L
V
A
S
I
------
V
V
ND
A
L
W
G
--
L
I
S
C
H
H
Y
S
P
H
F
T
N
---------------
H
A
-----
M
R
D
V
T
D
A
V
A
R
T
L
---
A
G
---------------------------
R
I
G
A
------
L
Q
A
V
A
-
R
A
R
L
---------
E
S
V
L
L
T
V
R
E
K
L
I
---------------------
T
D
F
N
D
AEH
M
T
V
E
------
L
L
D
D
M
A
P
D
L
----
M
D
V
-
V
D
A
D
G
V
A
I
F
H
G
-
N
----------
D
I
S
R
H
G
T
T
P
D
-
V
A
A
L
-----------
R
R
I
R
D
H
I
E
S
EHH
E
A
L
R
-
E
D
A
V
G
A
L
H
---
V
D
A
I
G
-
E
V
F
P
E
L
A
D
L
A
P
L
A
A
G
F
I
F
V
PLMPQS
R
S
A
L
L
W
T
R
R
E
Q
I
Q
Q
I
K
W
AGNPRKSF
D
L
W
Q
Q
T
V
R
GRARRWS
P
L
H
L
E
S
---
A
R
S
L
R
V
L
I
E
L
M
E
R
------
K
R
-
F
Q
Q
D
F
T
L
L
E
A
S
L
S
--
R
L
R
D
G
V
A
I
I
E
R
G
T
ANAAHR
L
L
F
V
N
----
T
A
F
A
D
--------
V
C
------
G
S
D
V
A
E
L
I
G
R
E
L
Q
T
L
Y
-----------
A
S
D
AP
R
A
N
V
E
L
L
-------------
Q
D
A
L
--
R
N
G---
R
A
A
Y
V
T
L
P
----
L
Q
V
S
D
-------
G
A
P
V
Y
R
Q
F
H
L
E
P
L
P
S
PSGVTA
H
W
L
L
Q
L
R
D------------------
14
Fugue
65.81
15%
-91
- C6 -
-
5F7C
-
?
A:
[12-723]
------------------------------------------------------------------LFDFDTELLRD
E
S
L
W
K
A
C
KPT
A
V
Y
E
K
DGD
I
C
V
T
V
P
F
Q
K
Q
L
L
------
A
N
D
M
V
A
-------------------
D
T
A
V
P
R
-
E
E
Y
--
T
L
I
I
R
Q
Y
NIG
I
T
R
---
L
F
L
G
F
G
E
Y
E
-------------
I
L
F
T
Q
--------------
D
G
T
K
R
A
V
INVEEPALDRWSE
L
-
L
---------
P
D
-
P
Q
E
T
L
D
------------
I
T
L
Y
-----------
P
DGK
R
E
I
R
L
AAYDHFSPPR
Y
D
G
L
P
I
A
---
F
C
K
------
R
T
G
K
K
E
R
A
T
L
S
F
E
S
R
P
D
E
------------
C
F
A
G
--------
T
G
E
R
F
F
K
M
D
L
----------------
S
G
Q
T
-----------
L
F
L
K
NQDGQGVNNRR
T
Y
K
N
I
P
F
Y
L
S
----------
S
R
M
Y
G
T
F
YHTC
A
H
S
K
L
S
LAGHSTRSV
Q
F
L
-------------
S
D
Q
A
M
L
D
A
F
V
I
A
G
---
D
T
---
M
E
E
I
L
R
G
Y
R
D
L
T
------------------------------------
G
Y
P
S
M
P
P
------
L
W
--
S
F
G
V
--
W
M
S
R
M
T
Y
F
S
A
D
E
V
N
E
I
C
D
--------
R
M
R
A
-----
E
H
Y
P
C
D
V
I
H
L
D
T
---
G
W
FRTDWLCEWKFNEERFPA
G
T
I
D
FTY
P
K
A
T
E
W
------
Y
K
G
L
L
-
K
Q
L
L
---------
D
M
G
V
T
C
I
K
T
D
F
G
---------------------
E
N
I
H
----
M
D
A
V
------
Y
K
G
M
K
P
E
L
L
----
N
N
L
Y
A
L
L
Y
Q
K
A
A
Y
E
I
-
T
K
--
E
V
TGDGI
V
W
A
R
A
A
W
A
G
C
-
Q
R
Y
P
L
H
W
GGDSCSS
W
D
G
M
A
G
S
L
K
G
---
G
L
H
F
G
L
S
G
F
A
F
W
S
---
H
D
V
P
G
-
F
-
H
T
L
P
N
F
M
N
S
I
V
A
E
D
V
Y
M
------
R
W
T
Q
F
G
V
------------------------------------
F
T
S
---
H
I
R
Y
H
G
T
N
K
R
----------
E
-
P
W
H
Y
P
A
I
A
P
L
V
K
K
W
W
K
L
R
Y
S
L
I
P
Y
----------
I
I
E
Q
S
----
K
L
A
V
E
--------
S
G
------
W
P
L
L
Q
A
L
I
L
H
H
P
E
D
K
L
C
W
H
--------
I
D
D
-----
E
Y
Y
F
-------------
G
-----
N
D
----
F
L
V
A
P
V
M
N
SEN
R
R
D
I
Y
L
-------
P
E
G
Q
W
V
N
F
F
T
G
E
R
L
Q
GGRWLKE
V
Y
V
P
LEE
M
P
V
Y
V
R
E
N
A
V
I
P
I
YPEEV
20
Fugue
64.22
18%
-
- C5 -
-
2WZP
-
GP16_BPLP2
R:
[1-375]
------------------------------------------------------------------------------------------------------
M
L
E
A
N
------
V
Y
D
N
F
N
---------------------
P
N
Y
Y
-
N
I
S
--
D
--------------------------------------
F
S
M
P
--------------
N
G
K
K
E
K
R
-------------
G
-
L
---------
P
I
-
P
K
A
---------------
R
C
Q
V
-----------
I
--------------------
N
Y
E
L
W
ETG
Y
L
Y
------
T
S
S
A
T
L
T
V
S
V
E
V
G
D
I
V
Q
I
------------
L
F
P
E
--------
V
V
P
I
E
----------------------
E
A
L
-----------
G
K
K
K
-----------
K
L
N
L
D
M
V
Y
L
V
----------
T
-------------------------
D
V
D
-------------
E
S
N
K
A
T
L
K
N
Y
F
W
A
MIE
S
L
---
D
V
P
N
A
I
T
K
T
T
N
F
------------------------------------
A
I
I
D
Y
L
I
DPNKNN
L
M
--
S
Y
G
Y
--
F
F
N
S
S
I
F
A
G
K
A
T
I
N
R
K
A
E
--------
T
-
S
S
-----
A
H
D
V
A
K
R
I
F
S
K
V
---
Q
F
---------------------------
Q
P
--------
T
T
T
I
Q
-
H
A
P
S
---------
E
T
D
P
R
N
L
L
F
I
N
F
---------------------
A
S
R
N
----
W
N
R
K
------
R
I
T
T
R
V
D
I
K
----
Q
S
V
T
M
D
T
E
T
I
V
-
E
R
S
-
A
Y
--
N
F
-----
A
V
V
F
V
K
N
K
A
T
-
D
D
Y
T
DPP--------
K
M
Y
I
A
K
N
N
G
---
D
V
I
D
-
Y
S
T
Y
H
G
D
G
---
T
D
L
P
D
-
V
----
R
T
A
K
T
L
F
Y
D
R
D
D
H
G
------
N
P
P
E
L
S
T
------------------------------------
I
K
V
---
E
I
S
P
---
S
T
I
V
T
R
------
L
I
-
F
N
Q
N
E
L
L
P
L
Y
V
N
D
L
V
D
I
W
Y
E
G
K
L
Y
----------
S
G
Y
I
A
----
D
R
V
K
T
--------
E
F
------
N
----------------------------------------------------------------------
D
----
R
L
I
F
V
-------
E
S
G
D
-----
K
P
N
V
I
---------------------------------
12
Fugue
62.52
17%
-84
- C6 -
-
4ZMU
-
?
A:
[5-345]
------------------------------------------------------------------------------------------------------
M
L
A
C
P
------
L
P
P
D
E
A
-------------------
L
R
Q
Q
A
L
D
D
M
A
--
L
V
D
T
P
A
------
E
---
H
Y
L
D
A
L
V
E
L
-------------
A
R
E
T
F
--------------
G
V
K
T
V
L
I
-------------
S
-
L
---------
I
D
H
D
R
Q
---------------
W
F
K
A
-----------
R
-----
I
G
-----------
L
D
A
E
Q
T
P
---
R
D
L
------
S
F
C
G
H
A
I
L
A
--
S
E
P
L
M
V
T
------------
D
A
S
R
--------
D
P
R
F
H
D
N
P
L
V
----------------
T
G
P
P
-----------
F
I
R
------------------
F
Y
A
G
----------
E
-------------------------
P
L
H
-------------
A
S
N
G
Q
A
I
G
T
L
C
L
I
---
D
P
---
S
P
R
L
L
D
L
R
E
G
R
Q
------------------------------------
L
N
R
L
S
I
L
------
A
E
--
G
Y
L
Q
--
L
R
S
---------
L
T
E
H
T
R
--------
F
L
R
Q
-----
E
I
D
R
E
Q
R
K
S
L
L
D
---
P
L
---------------------------
T
Q
L
W
N-----
R
A
G
F
H
-
A
L
H
Q
---------
H
E
L
E
L
A
R
A
S
D
-
Q
---------------------
R
I
G
I
----
I
Y
S
D
------
I
--------------------------
D
-
H
F
--
K
R
-----
I
N
D
T
L
G
H
R
A
G
-
D
S
V
L
-----------
R
E
A
A
S
R
L
R
A
---
A
---------
L
R
P
---
E
D
L
L
A
-
R
-
F
G
G
----
E
E
F
V
A
M
V
R
V
R
------
E
T
T
E
L
T
M
------------------------------------
I
A
N
---
R
I
R
E
L
M
E
A
T
---------------
P
I
D
C
A
G
T
S
V
----
P
V
T
I
S
A
G
C
T
----------
L
A
G
S
G
----
E
E
P
E
R
--------
A
L
------
A
R
A
D
A
A
L
Y
D
A
K
R
A
G
--------------------------------------------
R
N
----
R
V
V
S
V
------------------------------------------------------------------
7
HHSearch
34.79
11%
-201
- C8 -
-
5X5Y
-
?
F:
[63-128]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
P
L
G
---
L
F
L
------
G
I
L
L
A
Y
G
R
L
Y
L
E
S
E
M
T
V
L
------------
S
A
T
G
--------
M
S
Q
K
R
L
L
G
Y
T
----------------
M
A
P
A
-----------
L
L
V
A
-----------
I
L
V
A
W
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
33.66
26%
-139
* C8 *
-
2D9S
-
B:
[8-30]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
S
------
S
E
-
I
E
R
L
M
S
Q
G
Y
S
Y
Q
D
I
Q
K
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
33.09
11%
-169
- C8 -
-
5NIL
-
?
K:
[525-646]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
-----------
V
-----
A
V
-----------
I
S
L
V
V
G
G
---
I
G
V
------
M
N
I
M
L
V
S
V
T
E
R
T
R
E
I
G
I
R
------------
M
A
V
G
--------
A
R
A
S
D
V
L
Q
Q
F
----------------
L
I
E
A
-----------
V
L
V
C
-----------
L
V
G
G
A
L
G
I
T
L
----------
S
-------------------------
L
L
I
-------------
A
F
T
L
Q
L
F
L
P
---------------
G
W
E
I
G
F
S
P
L
------------------------------------
A
L
L
L
A
F
L
------
C
S
--
T
V
T
G
--
I
L
F
G
W
L
P
A
R
N
A
A
R
L
D
P
V
D
--------
A
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
32.89
6%
-228
- C8 -
-
5X5Y
-
?
G:
[63-119]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
P
M
A
---
A
L
I
------
G
C
L
V
G
L
G
T
L
A
S
N
S
E
L
T
I
M
------------
R
A
A
G
--------
V
S
L
S
R
I
V
W
A
V
----------------
M
K
P
M
-----------
L
V
L
M
-----------
L
A
G
I
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
27.05
33%
-40
- C8 -
-
4HNL
-
IMND1_ENTGE
A:
[338-391]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
A
V
N
T
-------------
H
L
N
I
H
LHNA
A
I
Q
E
T
I
E
L
P
A
N
T
Q
S
V
F
V
-------------
G
-
S
---------
P
Q
-
P
K
G
---------------
G
F
F
Y
-----------
P
-----
M
E
-----------
K
S
G
I
G
I
T
---
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
25.98
14%
-113
- C8 -
-
5NIL
-
?
K:
[525-598]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
V
A
------
V
I
S
L
V
V
G
------------------------------------
G
I
G
---
V
M
N
I
M
L
V
S
V
T
E
R
T
------
R
E
-
I
G
I
R
M
A
V
G
A
R
A
S
D
V
L
Q
Q
F
L
I
E
A
V
L
----------
V
C
L
V
G
----
G
A
L
G
I
--------
T
L
------
S
L
L
I
A
F
T
L
-------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
22.07
25%
181
- C1 -
-
2RMZ
-
?
A:
[719-726]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
I
H
D
R
------
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
19.88
12%
32
- C8 -
-
5DO7
-
ABCG5_HUMAN
A:
[369-398]
-------------------------------------------------------------------------------------------------------
G
V
L
L
------
R
R
V
T
R
N
-------------------
L
V
R
N
K
L
-
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
19.18
12%
32
- C8 -
-
5DO7
-
ABCG5_HUMAN
C:
[369-394]
-------------------------------------------------------------------------------------------------------
G
V
L
L
------
R
R
V
T
R
N
-------------------
L
V
R
N
K
L
-
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
17.77
18%
-36
* C6 *
-
1BHI
-
ATF2_HUMAN
A:
[1-38]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
D
------
D
K
--
P
F
L
C
--
T
A
P
G
C
G
Q
R
F
T
N
E
D
H
L
A
V
H
--------
K
H
K
H
-----
E
M
T
L
K
F
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------