@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1205: (2018-01-07 )
MIKFLGDFVMDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILNEWSEAPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYGQWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVINEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSGQAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYENFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHRLLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVANNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLVSIMDNKLTILPQI
Atome Classification :
(20 SA)
-------------------------------------------.....----..---..10........20......-..30---........40........50....-....60...-----.....70....-----....80...---------.....90........100.-----......110...----....120.....------..130.......140......-------.150.......160.......170.......180.......190.......200....---...-210...---------....220......---------------.230..---...------..240..-..-...250.--------------......260.--......270.......280.......290.-----.....---...300---..----.......310--.......320---..-......330.......340.---......350......--.360...-....370..--.---.----.....380...-...-.390.-------------------........400...----..----------..-------------410.......420.----......430.......440......---.--450.--.---..-.---....460.......470.---......480...--....490.......500...--....510-----.......520.......530.......540.......550-------.--.......560........570.......580......--.590.......600....-...610.......620.......630......--.640.......650-.........660.......-670.......680.......690.......700....-----...710.......720--------.........730......-.740.......750.......760---.........770.......780.......790-------------------.......800.------------......810.------------------......820-----------........830---.----....----....840.......850.----....-------...860.......870.-----------.....---------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------MI
K
F
L
----
G
D
---
F
V
M
DYNFNLEH
P
F
F
F
TNNDY-STD
T
---
S
I
K
Y
Q
V
SLPF
N
W
H
E
VMNND
E
W
V
Y
Q-YP
I
G
K
F
V
ER-----QG
W
K
I
H
I
SSEY-----N
S
S
H
E
L
L
Q
D
---------
V
A
K
I
C
H
EMRI
P
F
KHLSTED-----
K
F
I
MRN
G
K
L
V
SR----GFSG
K
F
I
T
CYP
N
------
Q
N
E
L
E
S
V
L
Q
R
L
E
S
A
L
K
QYNG
P
-------
Y
I
LSDKRWDEA
P
I
Y
L
R
YGVFRPSRDDEKK
V
A
I
D
E
LIVGDEVVKDERL
P
V
F
KIPKGIV
P
---
P
D
F
-
L
N
K
W
L
D
---------
K
K
DKKQGDF
P
F
I
I---------------DN
A
I
R
F---SNS------GG
I
Y
N
A
R
-LK-EDG
K
K
I
I
--------------
L
KEARPYTGL--GFDGTY
S
S
E
K
L
A
S
E
C
K
A
L
K
I
L
N
E
WSEA--
P
-----
K
I
Y
WH---GKI
W
-----
E
H
----
T
F
LG
I
E
HMKG--VPLNRWVTN----NF-
P
L
Y
E
V
V
D
K
T
K
D
Y
L
L
R
V
S
K
I
V
---
E
K
L
I
D
L
T
N
K
FHSENV--
Y
H
QDLHL-G
N
I
L
V
--KD--E---D----
E
I
S
I
I
D
W
E
Q
A
V
-FSN-
D
E
--
K
-------------------
V
V
H
K
VAAP
G
F
R
A
W
R
----
E
T----------LP-------------SEI
D
W
Y
G
I
R
Q
I
A
H
Y
----
L
YMPLVTTSD
L
T
Y
N
Y
V
S
QTRI
E
G
K
K
---
L
--
F
--
E
--
S
---LG-Y---
T
R
E
H
I
D
Y
V
E
S
L
L
S
Y
L
D
SK---CP
Q
I
EN
I
S
R
K
K
V
--
L
K
P
M
H
E
I
RTIE
S
E
Q
D
I
Q
D
F
I
--
I
K
L
L
R
GF-----TL
T
Y
G
Q
W
R
K
E
F
Q
SRF
F
P
V
H
Y
YGLNFNQGI
A
F
S
D
L
A
I
L
W
S
--------
Y
--
Q
Q
L
A
K
K
V
K-NFKF
D
D
Y
Y
E
I
R
T
Q
V
I
N
E
A
V
N
N
F
K
K
S
S
LS--GLFDGKI
G
T
I
W
L
I
Y
EFGE-
I
D
R
A
V
E
L
F
T
T
H
F
I
E
I
F
ENSQNKNLYSGQA
G
I
L
--
L
V
G
L
Y
F
LSKGEI---
D
N
K
L
G
E
E
I
L
I
R
L
R
E
Y
T
L
N
Y-IE
N
P
E
T
F
C
KVGASDVQSND
P
Y
E
N
FG
G
L
LYGHA
G
V
A
W
L
-----FG
E
A
Y
KL
T
G
E
S
I
Y
K----------NG
L
E
L
AVDK
E
L
V
A
Y
K
VDS-NN
S
L
QYSQG
H
R
L
L
P
Y
L
ATGSA
G
-----
L
L
L
L
INR
N
K
E
I
L
S
S
K
Y
L
K
Y
L
T
S
L
E
R
A
T
D
V
V
F
C
-------------------
V
L
P
G
L
F
NGFC
G
------------
L
E
V
A
N
N
I
Y
S
D------------------IDDNFS
G
Q
------------
K
K
L
I
E
Q
L
Y
R
-----
Y
----
L
C
VI----EE
G
F
V
I
AGDN
G
L
K
I
T
-
T
D
----
I
ASG-------
F
A
G
V
A
I
G
L
V
S
IMDN
K
L
T
-----------ILPQI---------------------------------------------------------
85
Fugue
58.12
17%
11
- C3 -
-
5DZT
1
?
A:
[4-992]
------------------------------------------N
L
I
N
V
L
S
I
N
E
R
C
---
F
L
L
K
Q
S
G
N
E
K
Y
D
I
K
N
L
Q
A
W
K
-
E
R
K
S
---
V
L
K
Q
D
D
L
D
Y
L
I
K
Y
K
Y
E
S
L
D
N
F
G
L
G
I
T
P
I
E
N
F
P
D
----------
K
E
V
A
I
Q
Y
-----
I
K
D
Q
S
W
Y
I
F
---------
F
E
S
I
L
D
S
Y
N
D
S
E
E
Q
L
L
E
V
D
ASYPF
R
Y
F
L
Q
Y
A
R
L
F
L
L
----
D
L
N
S
E
L
N
I
C
--
T
------
K
E
F
I
I
N
L
L
E
I
L
T
Q
E
L
I
H
L
T
S
K
-------
T
L
V
L
D
L
H
--------
R
F
I
Y
Y
L
K
K
R
F
N
S
K
K
D
I
I
A
F
Y
T
C
Y
P
E
L
M
---
R
I
T
V
V
R
M
R
Y
F
L
D
N
T
--
K
Q
M
-
L
I
R
V
T
E
---------
D
L
P
S
I
Q
N
C
F
N
I
Q
S
---------------
S
E
L
N
S
I
---
S
E
S
QGDSHS
R
G
K
T
V
S
T
-
L
T
F
S
D
G
K
K
I
V
--------------
Y
K
---
P
---------------
K
I
N
S
E
N
K
L
R
D
F
F
E
F
L
N
K
E
LE
A
-----
D
I
Y
I
V
---
K
K
V
T
-----
R
N
----
T
Y
F
Y
E
E
Y
I
D
N
--
I
E
I
N
N
----------------
I
E
E
V
K
K
Y
Y
E
R
Y
G
K
L
I
---
G
I
A
F
L
F
-------
N
V
----
T
D
L
H
Y
-
E
N
I
I
A
--
H
G
--
E
---
Y
----
P
V
I
I
----------
D
-
N
E
--
T
-------------------
F
F
Q
Q
N
I
P
I
E
F
G
N
---------------------------------------
S
A
T
V
D
A
K
Y
----
K
Y
L
D
S
I
M
V
T
G
L
V
P
K
---
N
T
P
I
M
N
N
E
---
K
--
I
--
S
--
F
---
I
S
-
Y
---
E
K
Y
I
V
T
G
M
K
S
I
L
M
K
A
K
D
S
---
K
K
K
I
L
A
Y
I
N
N
N
L
QN
L
I
V
R
N
V
I
R
P
T
Q
R
Y
A
D
M
L
E
F
S
Y
H
P
N
C
F
S
N
A
-----
I
E
R
E
K
V
L
H
N
M
W
A
Y
P
Y
K
N
K
K
V
V
H
Y
E
F
S
D
L
I
D
-
G
D
I
P
I
F
Y
N
--------
N
IS
K
T
S
L
I
A
S
D
-
G
C
L
V
E
D
F
Y
Q
--
E
S
A
L
N
R
C
L
N
K
I
N
D
L
C
-----
D
E
D
I
S
I
Q
T
V
W
L
E
I
A
L
N
I
-
Y
N
P
Y
-----
K
Y
I
N
D
L
K
N
Q
N
S
N
K
Y
I
Y
T
---
G
L
E
--
L
N
G
K
I
I
Q
A
C
Q
K
I
---
E
K
K
I
F
K
R
A
I
F
N
K
K
T
N
T
V
N
W
-
I
D
I
K
L
D
--
Q
D
W
N
V
G
I
L
N
N
N
M
Y
D
G
L
P
G
I
F
I
F
Y
V
A
L
K
Y
I
TKNH
K
Y
D
Y
V
I
E
C
I
K
N
S
I
Y
T
IPSEDILSAF
F
G
K
G
S
L
I
Y
P
L
L
V
D
Y
R
L
N
N
D
I
N
S
L
N
V
A
V
E
I
A
D
M
D
W
I
H
G
H
N
S
I
-----
I
K
V
L
L
L
L
S
E
I
T
E
D
E
K
Y
R
K
F
S
L
E
I
F
E
K
L
S
-------------------------
E
E
P
Y
F
N
F
R
G
------------
F
G
H
G
I
Y
S
Y
V
H
------------------
L
L
S
K
F
N
R
I
------------
D
K
A
N
S
L
L
H
K
-----
I
KNNS
W
C
K
G
----
T
V
G
E
L
L
A
T
D
I
N
K
T
I
E
-
Y
K
NKDC
L
C
H
G
-------
N
A
G
T
L
E
G
L
I
Q
L
A
K
K
D
P
E
-----------
T
Y
Q
Y
K
K
N
K
L
I
S
Y
M
L
K
Y
F
E
K
N
NTLKVAGSEYLESLGFFVG
I
S
G
V
G
Y
E
L
L
R
N
L
DSEIPNALLFE
88
Fugue
53.64
14%
9
* C5 *
-
4JSP
1
MTOR_HUMAN
A:
[10-1174]
E
R
A
A
K
C
R
A
Y
A
K
A
L
H
Y
K
E
L
E
F
Q
K
GPT
P
A
I
L
E
S
L
I
S
I
N
N
K
L
QQ
P
E
A
A
A
G
V
----
L
E
---
Y
A
M
K
H
F
G
E
L
E
I
Q
A
T
W
Y
E
K
L
H
E
W
E
D
A
---
L
V
A
Y
D
K
K
M
D
T
N
------
K
D
D
P
E
L
M
-
L
G
R
M
R
C
L
E
A
-----
L
G
E
W
G
Q
L
H
Q
Q
C
C
E
K
WT
L
V
N
D
E
T
Q
A
K
---------
M
A
R
M
A
A
A
A
A
W
G
L
G
Q
W
D
S
M
E
-----
E
Y
T
C
M
I
P
R
D
T
H
D
----
G
A
F
Y
R
A
V
L
A
L
H
Q
DL
F
S
L
A
Q
Q
C
I
D
K
A
R
D
L
L
D
A
E
L
T
A
M
A
G
E
SYS
R
A
Y
G
A
M
V
S
C
H
M
L
S
E
L
E
E
V
I
Q
Y
K
L
-
V
P
E
R
R
E
I
I
R
Q
I
W
W
E
R
L
Q
G
C
Q
R
I
V
E
D
W
Q
K
I
L
M
V
R
S
L
V
V
S
---
P
H
E
D
M
R
T
W
L
K
Y
A
S
L
C
G
K
S
G
R
L
A
L
A
H
K
T
L
V
L
L
L
GVDPSRQLD
H
P
L
P
TV
H
P
Q
V
T
Y
---
A
Y
M
------
K
N
M
W
K
S
A
-
R
K
-
I
D
A
F
Q
H
M
Q
H
F
V
Q
T
--------
M
Q
Q
Q
A
Q
H
A
I
A
--
T
E
D
Q
Q
H
K
Q
E
L
H
K
L
M
A
R
C
F
L
K
L
G
E
W
Q
L
N
--
L
-----
Q
G
I
N
E
ST
I
P
K
V
L
-----
Q
Y
----
Y
S
A
A
T
E
H
D
R
S
W
Y
K
A
W
H
A
W
A
V
M
----
N
F
-
E
A
V
L
H
Y
K
H
Q
N
Q
A
R
D
E
K
K
K
V
T
---
E
D
L
S
K
T
L
L
M
Y
T
V
P
A
V
Q
G
F
F
R
S
I
S
L
S
R
G
N
N
L
--
Q
D
--
T
---
L
----
R
V
L
T
L
W
F
D
Y
G
H
-
W
P
D
V
N
E
--
A
-------------------
L
V
E
G
V
K
A
I
Q
I
D
T
W
L
----
Q
V
----------
I
P
Q
L
I
A
R
I
DTPR
P
L
V
G
R
L
I
H
Q
L
L
T
D
I
G
R
Y
HPQA
L
I
Y
P
L
T
V
A
S
K
S
T
---
T
T
A
R
H
N
A
A
N
K
---
I
--
L
--
K
--
N
---
M
C
E
H
---
S
N
T
L
V
Q
Q
A
M
M
V
S
E
E
L
I
R
V
---
A
I
L
W
H
E
M
W
H
E
G
L
--
E
E
A
S
R
L
Y
F
G
E
R
N
V
K
G
M
F
E
V
L
--
E
P
L
H
A
M
M
ERGPQ
T
L
K
E
T
S
F
N
Q
A
Y
G
R
D
L
M
E
A
Q
E
W
C
R
K
Y
M
K
S
G
N
V
K
D
L
T
Q
A
W
D
--------
L
--
Y
Y
H
V
F
R
R
I
-
S
K
Q
L
P
Q
L
T
S
L
E
L
Q
Y
V
S
P
K
L
L
M
C
R
D
L
E
L
A
VP
G
T
Y
D
P
N
Q
P
I
I
----
R
I
Q
S
-
I
A
P
S
L
Q
V
I
T
S
K
-----
Q
R
P
R
K
L
T
L
M
G
S
N
G
H
------
E
F
V
F
L
L
K
G
H
E
---
D
L
R
Q
D
E
R
V
M
Q
L
F
G
L
V
N
T
L
L
-
A
N
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P
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L
R
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L
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Y
A
V
I
P
L
S
T
N
S
G
L
I
G
W
V
P
H
C
D
T
---------
L
H
A
L
I
R
D
Y
R
E
K
----------
K
K
I
L
L
N
I
E
H
R
I
M
L
R
M
A
P
D
-
Y
D
H
L
T
L
M
Q
K
V
E
V
F
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H
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V
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N
T
A
G
D
D
L
A
K
L
L
W
L
K
S
P
S
S
E
V
W
F
D
R
R
T
N
Y
T
R
S
L
A
V
M
S
M
V
G
Y
I
L
GLGDRHPSNLMLDRLSG
K
I
L
H
I
D
F
G
D
C
F
E
------------
V
A
M
T
R
E
K
F
P
E
KIPFRLT
R
M
L
T
N
A
M
EVTG
L
D
G
N
Y
R
I
T
------------
C
H
T
V
M
E
V
L
R
E
H
K
D
S
V
----
M
A
V
L
----
E
A
-
F
V
Y
--
D
P
L
L
N
W
R
L
M
D
----
T
N
T
A
-------
L
N
K
K
A
I
Q
I
I
N
R
V
R
D
K
L
T
GRDFSHDDTLD
V
P
T
Q
V
E
L
L
I
K
Q
A
T
S
H
E
N
L
C
Q
CYIGWCPFW---------------------------------
90
Fugue
52.54
14%
-5
- C1 -
-
5ME3
-
SCC2_ASHGO
A:
[47-1100]
-------------------------------------------
R
M
K
N
I
----
G
K
NLH
I
T
H
F
S
Y
I
M
L
S
I
L
Q
V
W
N
N
Y
D
Y
-
C
S
N
L
VSP
D
T
E
Q
L
H
D
L
I
A
H
H
A
A
T
Q
S
D
L
E
F
A
A
D
-
H
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D
T
I
L
K
K
C
F
S
N
I
S
K
Y
R
F
V
F
D
Q
F
V
-----
T
D
M
T
T
V
V
T
L
PDWPV
S
D
L
I
L
A
R
L
L
K
K
L
L
S
I
F
K
H
I
N
I
E
S
-----
V
A
L
Q
G
I
G
L
I
G
S
T
I
L
D
I
R
L
S
S
N
L
I
H
L
F
N
Y
------
P
E
D
I
D
G
L
F
K
A
Y
R
T
C
L
A
Y
C
T
N
S
-------
V
Q
H
H
T
P
Y
K
F
L
W
C
K
Q
L
D
V
L
T
K
L
K
E
M
G
S
K
L
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Q
K
F
L
S
L
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S
I
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A
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E
I
L
P
T
Y
C
S
T
L
L
T
S
E
L
I
N
M
Y
E
P
Y
-
L
K
L
V
L
S
---------
L
L
E
R
H
K
V
K
L
R
S
G
A
---------------
I
R
C
L
A
L
L
I
S
K
D
K
------
N
M
L
Y
T
P
I
-
V
K
-
E
T
I
E
N
R
L
T
D
SS
P
L
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K
D
A
I
L
E
L
I
E
L
G
S
S
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I
D
F
Y
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I
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Y
N
D
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M
L
V
R
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H
V
L
R
M
N
Q
I
I
Y
D
D
--
T
ED
I
I
I
K
A
Y
V
A
---
S
R
I
L
-----
R
R
I
EDE
E
D
V
I
I
E
T
A
R
S
--
E
L
L
K
R
W
I
L
S
IQCP
N
A
-
K
P
E
L
Q
I
K
N
C
R
V
S
I
R
V
I
A
Q
L
L
VGG
D
K
I
C
D
L
F
E
H
F
L
I
F
Y
V
--
L
N
K
N
A
H
T
-
E
D
Q
N
K
--
L
I
--
S
---
S
----
S
L
C
L
L
T
D
Q
V
I
E
-
M
V
I
-
E
N
--
E
-------------------
E
E
G
R
N
I
M
K
F
L
S
V
L
S
----
S
C
----------
Q
D
-------------
S
F
I
T
K
D
H
I
T
A
L
Y
P
Y
----
L
H
----
S
D
S
D
F
Q
L
H
I
L
K
V
Y
R
----
N
---
T
--
F
--
E
--
Q
---
L
S
-
H
---
F
K
--
P
K
F
L
Y
D
L
E
T
T
I
L
S
R
---
L
P
R
M
N
V
R
E
L
D
E
A
--
I
P
L
S
W
S
L
S
R
H
R
K
D
D
---
T
R
I
--
C
K
A
C
A
S
C
-----
L
G
Q
L
S
P
Y
I
A
N
A
T
T
D
P
R
P
D
G
K
L
Q
R
L
L
Y
L
A
T
G
F
A
R
F
C
S
F
E
N
NLKTREN
I
F
--
E
Y
V
T
K
C
L
L
-
M
F
T
E
N
I
H
H
V
I
R
R
I
A
T
K
N
L
V
K
I
A
S
R
--
Y
P
--
K
L
F
N
S
R
H
V
L
T
V
L
D
T
Q
F
E
K
G
I
L
D
I
Q
L
V
V
L
E
S
L
Y
D
F
F
L
A
E
E
R
R
S
L
I
S
I
N
D
G
I
C
S
A
L
V
S
R
Y
L
D
K
I
L
K
I
C
L
I
A
D
L
N
N
A
M
V
A
I
R
F
L
K
Q
I
L
T
Y
G
Y
T
N
P
S
L
C
V
P
T
V
I
A
L
T
A
S
P
N
S
Y
M
R
D
L
S
S
E
M
F
S
E
L
L
Q
G
Y
-----
E
S
M
A
F
N
C
L
N
Q
G
I
-
R
----------
L
G
T
E
Y
A
V
K
I
R
P
K
Q
F
H
E
D
S
-------
M
F
L
R
R
L
Q
Q
L
M
S
T
N
K
R
N
-----
R
S
K
F
L
K
V
V
K
K
T
V
F
S
N
Y
L
S
T
S
V
N
Y
E
E
S
C
Y
H
I
I
Y
-------------------
L
L
H
N
L
S
K
I
S
Y
D
N
M
L
E
L
Y
E
M
L
R
S
V
I
S
V
S
E
Y
F
S
D
R
------------------
I
S
E
R
L
D
G
F
NT
A
A
E
V
S
A
I
I
V
T
R
L
S
I
E
E
F
K
R
-----
F
----
M
F
E
Q
HHLS
E
A
K
L
T
L
L
D
D
E
N
L
R
N
K
-
S
V
----
A
A
L
D
D
QVGSLH
M
E
N
I
F
L
G
Y
E
N
P
I
N
N
K
D
Y
-----------
C
W
K
Y
I
S
T
L
HR----------------------------------------------------
86
Fugue
45.91
12%
-9
* C7 *
-
2PZI
5
PKNG_MYCTU
A:
[1-677]
-------------------------------------------------------------------------------
G
S
H
---
M
L
G
-------------------------
G
G
L
V
E
I
-----
P
R
A
P
D
I
D
P
L
E
A
-----
L
M
T
N
P
V
V
P
E
---------
S
K
R
F
C
W
N
C
G
R
P
V
G
R
S
G
A
S
E
-----
G
W
C
P
Y
C
G
S
P
Y
S
F
----
L
-----------------------------------------------------------------------------
P
Q
L
N
P
G
D
I
V
----------------------------------------------
A
G
Q
Y
E
V
---------------
K
G
C
I
A
H
---
G
G
L
------
G
W
I
Y
L
A
L
D
R
N
-
V
N
G
R
P
V
V
--------------
L
K
G
L
V
H
S
-------
G
D
A
E
A
Q
A
M
A
M
A
E
R
Q
F
L
A
E
V
V
-
H
P
S
I
--
V
-----
Q
I
F
N
F
---
V
E
H
T
D
RHG
D
P
V
----
G
Y
I
V
M
E
Y
V
G
G
--
Q
S
L
K
Q
K
L
P
--------------------
V
A
E
A
I
A
Y
L
---
L
E
I
L
P
A
L
S
Y
L
H
S
I
G
L
--
V
Y
N
D
L
K
P
-
E
N
I
M
L
---
T
--
E
---
E
----
Q
L
K
L
I
D
L
G
A
V
S
R
I
N
S
-
F
G
--
Y
-------------------
L
Y
G
T
P
G
F
Q
A
P
E
I
V
R
----
T
G
----------
P
T
-------------
V
A
T
D
I
Y
T
V
G
R
T
L
A
A
----
L
T
L
D
L
P
T
R
N
G
R
Y
V
D
G
L
P
E
D
D
P
V
L
K
T
---
Y
------------------------
D
S
Y
G
R
L
L
R
R
A
I
D
P
---
D
P
R
Q
R
F
T
T
A
E
E
M
--
S
A
Q
L
T
G
V
L
R
E
V
V
A
Q
D
T
G
V
P
R
--
P
G
L
S
T
I
F
-----
S
P
S
R
S
T
F
G
V
D
L
L
V
A
H
T
D
V
Y
L
D
G
Q
V
H
A
E
K
L
T
A
N
E
I
V
T
A
L
S
--------
V
--
P
L
V
D
P
T
D
V
A
A
S
V
L
Q
A
T
V
L
S
Q
P
V
Q
T
L
D
S
L
R
A
A
R
H
G
D
F
S
--
E
S
V
E
L
P
L
M
E
V
R
A
L
L
D
L
G
D
-
V
A
K
A
T
R
K
L
D
D
L
A
E
R
V
---------
G
W
R
W
R
L
V
W
--
Y
R
A
V
A
E
L
L
T
G
-----
D
Y
D
S
A
T
K
H
F
T
E
V
L
D
T
F
P
G
E
-
L
A
P
K
L
A
L
A
A
T
A
E
L
A
G
N
T
D
E
H
K
F
Y
Q
T
V
W
S
T
N
D
G
V
I
S
A
A
-----
F
G
L
A
R
A
R
S
A
E
G
D
R
V
----------
G
A
V
R
T
L
D
----------------
E
V
P
P
T
S
R
H
F
T
T
A
R
L
T
S
A
V
-----
T
L
L
V
T
E
E
Q
I
R
D
A
A
R
R
V
E
A
L
P
P
T
E
P
R
V
L
Q
I
R
A
L
-------------------
V
L
G
G
A
L
D
W
L
K
D
------------
N
K
A
S
T
N
H
I
L
G
------------------
F
P
F
T
S
H
G
L
------------
R
L
G
V
E
A
S
L
R
-----
S
----
L
A
R
V
--------------------------------------
A
P
T
Q
R
H
R
Y
T
L
V
D
M
A
N
K
-----------
V
R
P
-----------------------------------------------------------
105
HHSearch
45.14
18%
-41
- C6 -
-
2X0G
-
DAPK1_HUMAN
A:
[8-268]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
D
D
Y
Y
D
T
---------------
G
E
E
L
G
S
---
G
Q
F
------
A
V
V
K
K
C
R
-
E
K
-
S
T
G
L
Q
Y
A
--------------
A
K
F
I
K
K
R
R
T
K
--
S
S
R
R
G
V
S
R
E
D
I
E
R
E
V
S
I
L
K
E
I
-
Q
H
P
N
V
--
I
-----
T
L
H
E
V
---
Y
E
N
K
-----
T
D
----
V
I
L
I
L
E
L
V
A
G
--
G
E
L
F
D
F
L
A
E
----
K
E
-
S
L
T
E
---------
E
E
A
T
E
F
L
---
K
Q
I
L
N
G
V
Y
Y
L
H
S
L
Q
I
--
A
H
F
D
L
K
P
-
E
N
I
M
L
--
L
D
--
R
---
N
VP
K
P
R
I
K
I
I
D
F
G
L
A
H
-
K
I
D
-
F
G
N-
E
-------------------
F
K
N
I
F
G
T
P
E
F
V
A
P
E
----
I
V
N
YEP------
L
G
-------------
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
----
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
T
L
A
N
V
S
A
V
N
Y
---
E
--
F
--
E
--
D
EYF
S
N
-
T
---
S
A
L
A
K
D
F
I
R
R
L
L
V
K
D
P
K
K
---
R
M
T
I
Q
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
HHSearch
44.94
18%
-39
- C6 -
-
4B4L
3
DAPK1_HUMAN
A:
[10-270]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
D
D
Y
Y
D
T
---------------
G
E
E
L
G
S
---
G
Q
F
------
A
V
V
K
K
C
R
-
E
K
-
S
T
G
L
Q
Y
A
--------------
A
K
F
I
K
K
R
R
T
K
--
S
S
R
R
G
V
S
R
E
D
I
E
R
E
V
S
I
L
K
E
I
-
Q
H
P
N
V
--
I
-----
T
L
H
E
V
---
Y
E
N
K
-----
T
D
----
V
I
L
I
L
E
L
V
A
G
--
G
E
L
F
D
F
L
A
E
----
K
E
-
S
L
T
E
---------
E
E
A
T
E
F
L
---
K
Q
I
L
N
G
V
Y
Y
L
H
S
L
Q
I
--
A
H
F
D
L
K
P
-
E
N
I
M
L
--
L
D
--
R
---
N
VP
K
P
R
I
K
I
I
D
F
G
L
A
H
-
K
I
D
-
F
G
N
-
E
-------------------
F
K
N
I
F
G
T
P
E
F
V
A
P
E
----
I
V
N
YEP------
L
G
-------------
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
----
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
T
L
A
N
V
S
A
V
N
Y
---
E
--
F
--
E
--
D
EYF
S
N
-
T
---
S
A
L
A
K
D
F
I
R
R
L
L
V
K
D
P
K
K
---
R
M
T
I
Q
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
44.17
27%
-241
- C4 -
-
4BC6
2
STK10_HUMAN
A:
[110-161]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
V
V
C
---
R
Q
M
L
E
A
L
N
F
L
H
S
K
R
I
--
I
H
R
D
L
K
A
-
G
N
V
L
M
--
T
L
--
E
---
G
----
D
I
R
L
A
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
42.53
27%
-212
- C4 -
-
2J7T
1
STK10_HUMAN
A:
[118-166]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
V
V
C
---
R
Q
M
L
E
A
L
N
F
L
H
S
K
R
I
--
I
H
R
D
L
K
A
-
G
N
V
L
M
--
T
L
--
E
---
G
----
D
I
R
L
A
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107
HHSearch
42.02
15%
-88
- C6 -
-
5EYK
1
AUKBA_XENLA
B:
[7-256]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
T
I
D
D
F
D
I
---------------
V
R
P
L
G
K
---
G
K
F
------
G
N
V
Y
L
A
R
-
E
K
-
Q
N
K
F
I
M
A
--------------
L
K
V
L
F
K
S
Q
L
-----
E
K
E
G
V
E
H
Q
L
R
R
E
I
E
I
Q
S
H
L
-
R
H
P
N
I
--
L
-----
R
M
Y
N
Y
---
F
H
D
R
-----
K
R
----
I
Y
L
M
L
E
F
A
P
R
--
G
E
L
Y
K
E
L
Q
K
----
H
G
-
R
F
D
E
---------
Q
R
S
A
T
F
M
---
E
E
L
A
D
A
L
H
Y
C
H
E
R
K
V
--
I
H
R
D
I
K
P
-
E
N
L
L
M
--
G
Y
--
K
---
G
----
E
L
K
I
A
D
F
G
W
S
V
-
H
A
P
-
S
L
--
R
-------------------
R
R
T
M
C
G
T
L
D
Y
L
P
P
E
----
M
I
EGKT------
H
D
-------------
E
K
V
D
L
W
C
A
G
V
L
C
Y
E
----
F
L
V
G
M
P
P
F
D
S
P
S
H
T
E
T
H
R
R
I
V
N
V
D
L
---
K
--
F
--
P
------
P
F
-
L
---
S
D
G
S
K
D
L
I
S
K
L
L
R
Y
H
P
P
Q
---
R
L
P
L
K
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
41.21
27%
-222
- C4 -
-
4USE
1
STK10_HUMAN
A:
[118-168]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
V
V
C
---
R
Q
M
L
E
A
L
N
F
L
H
S
K
R
I
--
I
H
R
D
L
K
A
-
G
N
V
L
M
--
T
L
--
E
---
G
----
D
I
R
L
A
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108
HHSearch
40.85
16%
-104
* C6 *
-
5K00
1
MELK_HUMAN
A:
[5-255]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
L
K
Y
Y
E
L
---------------
H
E
T
I
G
T
---
G
--------
A
K
V
K
L
A
C
-
H
I
-
L
T
G
E
M
V
A
--------------
I
K
I
M
D
K
N
T
L
-------
G
S
D
L
P
R
I
K
T
E
I
E
A
L
K
N
L
-
R
H
Q
H
I
--
C
-----
Q
L
Y
H
V
---
L
E
T
A
-----
N
K
----
I
F
M
V
L
E
Y
C
P
G
--
G
E
L
F
D
Y
I
I
S
----
Q
D
-
R
L
S
E
---------
E
E
T
R
V
V
F
---
R
Q
I
V
S
A
V
A
Y
V
H
S
Q
G
Y
--
A
H
R
D
L
K
P
-
E
N
L
L
F
--
D
E
--
Y
---
H
----
K
L
K
L
I
D
F
G
L
C
A
-
K
P
--------------------------------
S
L
A
Y
A
A
P
E
----
L
I
Q
GKSY-----
L
G
-------------
S
E
A
D
V
W
S
M
G
I
L
L
Y
V
----
L
M
C
G
F
L
P
F
D
D
D
N
V
M
---
A
L
Y
K
K
I
M
R
G
K
Y
D
--
V
--
P
------
K
W
-
L
---
S
P
S
S
I
L
L
L
Q
Q
M
L
Q
V
D
P
K
K
---
R
I
S
M
K
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
40.78
27%
-208
- C4 -
-
5AJQ
2
STK10_HUMAN
A:
[115-164]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
V
V
C
---
R
Q
M
L
E
A
L
N
F
L
H
S
K
R
I
--
I
H
R
D
L
K
A
-
G
N
V
L
M
--
T
L
--
E
---
G
----
D
I
R
L
A
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
HHSearch
40.40
16%
12
- C6 -
-
2Y7J
1
PHKG2_HUMAN
A:
[91-356]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
Y
Q
K
Y
D
P
---------------
K
D
V
I
G
R
---
G
V
S
------
S
V
V
R
R
C
V
-
H
R
-
A
T
G
H
E
F
A
--------------
V
K
I
M
E
V
T
A
E
R
L
S
P
E
Q
L
E
E
V
R
E
A
T
R
R
E
T
H
I
L
R
Q
V
A
G
H
P
H
I
--
I
-----
T
L
I
D
S
---
Y
E
S
S
-----
S
F
----
M
F
L
V
F
D
L
M
R
K
--
G
E
L
F
D
Y
L
T
E
----
K
V
-
A
L
S
E
---------
K
E
T
R
S
I
M
---
R
S
L
L
E
A
V
S
F
L
H
A
N
N
I
--
V
H
R
D
L
K
P
-
E
N
I
L
L
--
D
D
--
N
---
M
----
Q
I
R
L
S
D
F
G
F
S
C
-
H
L
E
-
P
G
E
-
K
-------------------
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
----
I
L
K
C
S
M
D
ETHPG
Y
G
-------------
K
E
V
D
L
W
A
C
G
V
I
L
F
T
----
L
L
A
G
S
P
P
F
W
H
R
R
Q
I
L
---
M
L
R
M
I
M
E
G--
Q
YQ
F
SS
P
--
E
W--
D
D
-
R
---
S
S
T
V
K
D
L
I
S
R
L
L
Q
V
D
P
E
A
---
R
L
T
A
E
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111
HHSearch
40.37
15%
-78
- C6 -
-
4LQS
1
CBK1_YEAST
A:
[98-442]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
S
L
E
D
F
H
T
---------------
V
K
V
I
G
K
---
G
A
F
------
G
E
V
R
L
V
Q
-
K
K
-
D
T
G
K
I
Y
A
--------------
M
K
T
L
L
K
S
E
M
Y
-----
K
K
---------------
S
-
D
S
P
W
V
--
V
-----
S
L
Y
Y
S
---
F
Q
D
A
-----
Q
Y
----
L
Y
L
I
M
E
F
L
P
G
--
G
D
L
M
T
M
L
I
R
----
W
Q
-
L
F
T
E
---------
D
V
T
R
F
Y
M
---
A
E
C
I
L
A
I
E
T
I
H
K
L
G
F
--
I
H
R
A
I
K
P
-
D
N
I
L
I
--
D
I
--
R
---
G
----
H
I
K
L
S
D
F
G
L
S
T
-
G
F
H
-
K
T
--
H
D
S
N
YNRQQ
I
Q
T
W
R
KSRRLM
A
Y
S
T
V
G
T
P
D
Y
I
A
P
E
----
I
F
L
YQG------
Y
G
-------------
Q
E
C
D
W
W
S
L
G
A
I
M
Y
E
----
C
L
I
G
W
P
P
F
C
S
E
T
P
Q
E
T
Y
R
K
I
M
N
F
E
Q
T
L
-
Q
--
F
--
P
--
D
D--
I
H
-
I
---
S
Y
E
A
E
D
L
I
R
R
L
L
T
H
A
D
Q
R
LGR
H
G
G
A
D
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106
HHSearch
40.18
14%
-63
- C6 -
-
2WEL
7
KCC2D_HUMAN
A:
[2-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
D
E
Y
Q
L
---------------
F
E
E
L
G
K
---
G
A
F
------
S
V
V
R
R
C
M
-
K
I
-
P
T
G
Q
E
Y
A
--------------
A
K
I
I
N
T
K
K
L
------
S
A
R
D
H
Q
K
L
E
R
E
A
R
I
C
R
L
L
-
K
H
P
N
I
--
V
-----
R
L
H
D
S
---
I
S
E
E
-----
G
F
----
H
Y
L
V
F
D
L
V
T
G
--
G
E
L
F
E
D
I
V
A
----
R
E
-
Y
Y
S
E
---------
A
D
A
S
H
C
I
---
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
--
V
H
R
D
L
K
P
-
E
N
L
L
L
--
A
S
--
K
SKG
A
----
A
V
K
L
A
D
F
G
L
A
I
-
E
V
Q
-
G
D
QQ
A
-------------------
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
----
V
L
R
KDP------
Y
G
-------------
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
----
L
L
V
G
Y
P
P
F
W
D
E
D
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
---
D
--
F
--
P
--
S
PEW
D
T
-
V
---
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
---
R
I
T
A
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
39.29
27%
-212
- C4 -
-
4USD
1
STK10_HUMAN
A:
[118-184]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
V
V
C
---
R
Q
M
L
E
A
L
N
F
L
H
S
K
R
I
--
I
H
R
D
L
K
A
-
G
N
V
L
M
--
T
L
--
E
---
G
----
D
I
R
L
A
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
39.03
27%
-176
- C4 -
-
4AOT
1
STK10_HUMAN
A:
[118-182]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
V
V
C
---
R
Q
M
L
E
A
L
N
F
L
H
S
K
R
I
--
I
H
R
D
L
K
A
-
G
N
V
L
M
--
T
L
--
E
---
G
----
D
I
R
L
A
D
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97
HHSearch
38.48
16%
-40
- C6 -
-
1TKI
-
B:
[20-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
E
K
Y
M
I
---------------
A
E
D
L
G
R
---
G
E
F
------
G
I
V
H
R
C
V
-
E
T
-
S
S
K
K
T
Y
M
--------------
A
K
F
V
K
V
K
G
---------
T
D
Q
V
L
V
K
K
E
I
S
I
L
N
I
A
-
R
H
R
N
I
--
L
-----
H
L
H
E
S
---
F
E
S
M
-----
E
E
----
L
V
M
I
F
E
F
I
S
G
--
L
D
I
F
E
R
I
N
T
----
S
A
F
E
L
N
E
---------
R
E
I
V
S
Y
V
---
H
Q
V
C
E
A
L
Q
F
L
H
S
H
N
I
--
G
H
F
D
I
R
P
-
E
N
I
I
Y
--
Q
T
RR
S
---
S
----
T
I
K
I
I
E
F
G
Q
A
R
-
Q
L
K
-
P
G
D-
N
-------------------
F
R
L
L
F
T
A
P
E
Y
Y
A
P
E
----
V
H
QHDV------
V
S
-------------
T
A
T
D
M
W
S
L
G
T
L
V
Y
V
----
L
L
S
G
I
N
P
F
L
A
E
T
N
Q
Q
---
I
I
E
N
I
M
N
AEY
T
--
F
--
D
--
E
EAF
K
E
-
I
---
S
I
E
A
M
D
F
V
D
R
L
L
V
K
E
R
K
S
---
R
M
T
A
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
HHSearch
38.26
13%
-83
- C6 -
-
3C0I
1
CSKP_HUMAN
A:
[20-283]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
F
E
D
V
Y
E
L
---------------
C
E
V
I
G
K
---
G
P
F
------
S
V
V
R
R
C
I
-
N
R
-
E
T
G
Q
Q
F
A
--------------
V
K
I
V
D
V
A
K
F
T
---
S
S
P
G
L
S
T
E
D
L
K
R
E
A
S
I
C
H
M
L
-
K
H
P
H
I
--
V
-----
E
L
L
E
T
---
Y
S
S
D
-----
G
M
----
L
Y
M
V
F
E
F
M
D
G
--
A
D
L
C
F
E
I
V
K
----
R
A
-
D
A
G
F
-----
V
Y
S
E
A
V
A
S
H
Y
M
---
R
Q
I
L
E
A
L
R
Y
C
H
D
N
N
I
--
I
H
R
D
V
K
P
-
H
C
V
L
L
--
A
S
--
K
ENS
A
----
P
V
K
L
G
G
F
G
V
A
I
-
Q
L
G
-
E
S
GL
V
-------------------
A
G
G
R
V
G
T
P
H
F
M
A
P
E
----
V
V
K
REP------
Y
G
-------------
K
P
V
D
V
W
G
C
G
V
I
L
F
I
----
L
L
S
G
C
L
P
F
Y
G
T
K
E
R
L
F
E
G
I
I
K
G
K
Y
K
---
M
--
N
--
P
RQ
W
---
S
H
-
I
---
S
E
S
A
K
D
L
V
R
R
M
L
M
L
D
P
A
E
---
R
I
T
V
Y
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
Fugue
37.57
14%
-18
- C6 -
-
1KOB
1
?
A:
[23-374]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
D
Y
D
K
F
Y
E
D
I
W
---
K
K
Y
-
V
P
Q
P
V
E
---------
V
K
Q
G
S
V
Y
D
-
Y
Y
D
I
---------------
L
E
E
L
G
S
---
G
A
F
------
G
V
V
H
R
C
V
-
E
K
-
A
T
G
R
V
F
V
--------------
A
K
F
I
N
T
--------
P
Y
P
L
D
K
Y
T
V
K
N
E
I
S
I
M
N
Q
L
H
-
H
P
K
L
--
I
-----
N
L
H
D
A
---
F
E
D
K
-----
Y
E
----
M
V
L
I
L
E
F
L
S
G
--
G
E
L
F
D
R
I
A
A
----
E
D
-
Y
K
M
S
--------
E
A
E
V
I
N
Y
M
---
R
Q
A
C
E
G
L
K
H
M
H
E
H
S
I
--
V
H
L
D
I
K
P
-
E
N
I
M
C
ET
K
K
--
A
---
S
----
S
V
K
I
I
D
F
G
L
A
T
K
L
N
P
-
D
E
--
I
-------------------
V
K
V
T
T
A
T
A
E
F
A
A
P
E
I
V
D
R
E
P
----------
V
G
-------------
F
Y
T
D
M
W
A
I
G
V
L
G
Y
V
----
L
L
S
G
L
S
P
F
A
G
E
D
D
L
E
T
L
Q
N
V
K
R
C
D
W
---
E
--
F
--
D
--
E
---
D
A
-
F
SSV
S
P
E
A
K
D
F
I
K
N
L
L
Q
K
E
P
R
K
---
R
L
T
V
H
D
A
L
E
H
P
W
--
L
K
G
D
H
S
N
L
T
S
R
I
P
S
S
R
Y
N
K
I
--
R
Q
K
I
K
E
--------
K
Y
A
D
W
P
A
P
Q
P
A
I
G
R
I
A
N
F
S
S
L
R
K
H
R
P
Q
E
Y
Q
I
Y
D
S
Y
F
D
--------
R
--
K
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------