@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1254: (2018-01-08 )
MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFERNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKHIGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKSALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIVTHNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG
Atome Classification :
(23 SA)
.........10........20........---30........40........50........60........70........80........90-........100.......110...-.-....120..--------.....130.......140.......150.......160.......170.......180.......190.......200.......210-.--.......220.......230.......240.......250.......260.....---------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSTYNWDEK
H
I
L
TFPEE
K
V
ALST
K
D
V
H
V
Y
---YGKNESIKGI
D
M
Q
F
ER
N
K
I
T
A
L
IGPSGS
G
K
S
T
Y
L
R
S
L
N
RMNDT
I
D
I
A
K
V
T
G
Q
I
L
Y
RGIDVNR-PE
I
N
V
Y
E
M
R
K
H
I
G
M
V
FQRP
N
-
P
F
A
-
K
-
S
I
Y
R
N
I
T
F
A
--------
H
ERAGV
K
D
K
Q
V
L
D
E
I
V
E
T
S
L
R
Q
A
A
L
W
D
Q
V
K
D
D
L
H
K
S
A
L
TLSGGQQ
Q
R
L
C
I
A
R
AISVKP
D
I
L
L
MDEPASALDP
I
A
T
M
Q
L
E
E
T
M
F
E
LKK--D--
F
T
I
I
I
V
TH
N
M
Q
Q
A
ARASDY
T
G
F
F
Y
L
G
D
L
I
EYDK
T
A
T
I
F
QNAKLQSTNDYVSGHFG---------------------------------------------------------------------------------------------
12
PsiBlast_PDB
80.99
31%
-48
- C1 -
-
4U00
1
?
A:
[5-238]
--------------------
I
R
I
R
N
L
H
K
W
---
F
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
-----
G
E
V
V
V
D
G
L
S
V
-
K
-
D
D
R
A
L
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
-
L
F
P
-
H
M
T
V
L
E
N
V
T
L
A
--------
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
----
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
--------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
79.72
34%
18
- C1 -
-
3C4J
2
?
B:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
13
PsiBlast_PDB
79.03
31%
-46
- C1 -
-
4U02
-
?
A:
[5-238]
--------------------
I
R
I
R
N
L
H
K
W
---
F
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
-----
G
E
V
V
V
D
G
L
S
V
-
K
-
D
D
R
A
L
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
-
L
F
P
-
H
M
T
V
L
E
N
V
T
L
A
--------
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
----
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G-
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
--------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
78.80
34%
20
- C1 -
-
3C4J
2
?
A:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
RKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
7
PsiBlast_PDB
78.64
34%
17
- C1 -
-
2OLJ
3
?
A:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
21
PsiBlast_CBE
78.09
34%
-45
- C1 -
-
4YMV
1
?
A:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
78.00
34%
-48
- C1 -
-
4YMW
-
?
J:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
77.80
34%
-43
- C1 -
-
4YMU
1
?
A:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
77.58
34%
-44
- C1 -
-
4YMV
1
?
J:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
77.56
34%
-43
- C1 -
-
4YMT
-
?
J:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
76.86
34%
17
- C1 -
-
2OLK
2
?
B:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
3
PsiBlast_PDB
76.67
34%
-45
- C1 -
-
4YMU
1
?
J:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
76.04
34%
-44
- C1 -
-
4YMS
-
?
J:
[6-237]
------------------------
D
V
Y
K
N
---
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
-----
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
-
H
L
T
A
I
E
N
I
T
L
A
--------
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
---
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
75.92
34%
18
- C1 -
-
2OLK
1
?
D:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
23
PsiBlast_CBE
75.45
34%
14
- C1 -
-
3C41
2
?
K:
[1-242]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
16
PsiBlast_PDB
75.31
29%
-25
- C1 -
-
3TUZ
1
METN_ECOLI
C:
[23-256]
---------
H
M
I
-----
K
L
S
N
I
T
K
V
F
H
Q
G
---
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
-----
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
A
L
P
--------
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
G
D
--
K
H
D
S
Y
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
RL
G
--
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
----------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
75.24
34%
18
- C1 -
-
2OUK
-
?
A:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
RKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
68
Fugue
74.91
28%
-23
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
---------
H
M
I
K
L
S
N
-----
I
T
K
V
F
H
Q
G
---
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
-----
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
-
R
-
T
V
F
G
N
V
A
L
P
--------
L
E
L
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
--
R
LG
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
LDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
6
PsiBlast_PDB
74.77
34%
16
- C1 -
-
3C41
2
?
J:
[1-242]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
8
PsiBlast_PDB
74.73
34%
16
- C1 -
-
2OLK
1
?
A:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
10
PsiBlast_PDB
74.26
34%
15
- C1 -
-
2Q0H
3
?
A:
[23-263]
---------------------
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
RKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
32
PsiBlast_CBE
73.43
34%
20
- C1 -
-
2OLJ
2
?
B:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
30
PsiBlast_CBE
72.79
34%
18
- C1 -
-
2OLK
1
?
C:
[22-263]
--------------------
L
Q
M
I
D
V
H
Q
L
KKS
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
-----
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
-
H
M
T
V
L
N
N
I
T
L
A
PMKVRKWP
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
------------
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
--
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------