@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1561: (2018-01-14 )
MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGSSMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSVLKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEAKENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISLFMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPFISTFFMLFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60-.....--.----..70.--..--..-...80..-...-----..-.90-........100------..-....--..110..---.....120....------...130.......140-----...-.....150.......160.......170.......180.......190.......200......-.210.-.......220..-.....230.......240.......250.......260.......270.......280.......290.......300.......310-.......320-.-......330.......340.......350----------------------.--------------------------------.-----------------------.......360.......370.......380.......390.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MRN
M
W
V
V
I
K
E
T
Y
L
R
H
V
ES
W
S
F
F
F
M
V
I
S
P
F
L
F
L
G
I
S
VGIGHIQGSSMAKNN
K
V
A
V
V
T
T
V
P
S
V
-
A
E
G
L
K
--N----VNGVN--FD--YK-DE
A
S
A
K
E
-
A
I
K
-----
E
E
-KL
K
-
G
Y
L
T
IDQED
S
-------
V
L
-
K
A
V
Y--HGETSLE---N
G
I
K
F
E
V
T
G
T
L
N
------
E
L
Q
N
Q
L
N
RSTAS
L
S
Q
------
E
Q
E
-
K
R
L
A
Q
T
I
Q
F
T
E
K
I
D
E
A
K
E
N
K
K
F
I
Q
T
I
A
A
G
A
L
G
F
F
L
Y
M
I
L
I
T
YAG
V
T
A
Q
E
V
A
S
EKGT
K
I
M
E
V
V
F
S
-
S
I
-
R
A
-
S
H
Y
F
Y
A
R
M
M
A
L
F
-
L
V
I
L
T
H
I
G
I
Y
V
V
G
G
L
A
A
V
L
L
FKD
L
P
F
L
A
Q
S
G
I
L
D
HLGD
A
I
S
L
N
T
L
L
F
I
L
I
S
L
F
M
Y
V
V
L
A
A
F
L
G
S
M
VSRPEDSGK
A
L
S
P
L
M
I
L
I
MG
G
F
F
-
G
V
T
A
LGAAGD-
N
-
L
L
L
KIGSY
I
P
F
I
S
T
F
F
M
L
F
R
T
I
N
DYAG------------------------
G
--------------------------------
A
-----------------------
E
A
W
I
S
L
A
I
T
V
I
F
A
V
V
A
T
G
F
I
G
R
M
Y
A
S
L
V
L
QTDD
L
G
I
W
K
T
F
K
R
A
LSYK
11
PsiBlast_PDB
68.43
28%
139
- C2 -
-
5KUD
-
CR6AA_BACTU
A:
[140-331]
---------------------------------------------------------------------------
N
I
V
D
--
N
N
--
S
D
-
D
D
A
I
A
K
--
A
I
K
-----
D
F
-
K
A
R
-
C
G
I
L
I
K
E
A
K
Q
-------
Y
E
-
E
A
A
K
--
N
I
V
T
S
L
D
Q
F
L
H
G
D
Q
K
K
L
E
G
V
I
N
I
Q
K
R
L
K
E
V
Q
T
A
L
N
Q
A
H
G
E
S
S
P
A
H
K
E
L
L
E
K
V
-
K
N
L
K
T
T
L
E
R
T
I
K
A
E
Q
D
L
E
K
K
V
E
Y
S
F
L
L
G
P
L
L
G
F
V
V
Y
E
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
67.43
28%
153
- C2 -
-
5KUC
-
CR6AA_BACTU
A:
[140-325]
---------------------------------------------------------------------------
N
I
V
D
--
N
N
--
S
D
-
D
D
A
I
A
K
--
A
I
K
-----
D
F
-
K
A
R
-
C
G
I
L
I
K
E
A
K
Q
-------
Y
E
-
E
A
A
K
--
N
I
V
T
S
L
D
Q
F
L
H
G
D
Q
K
K
L
E
G
V
I
N
I
Q
K
R
L
K
E
V
Q
T
A
L
N
Q
A
H
G
E
S
S
P
A
H
K
E
L
L
E
K
V
-
K
N
L
K
T
T
L
E
R
T
I
K
A
E
Q
D
L
E
K
K
V
E
Y
S
F
L
L
G
P
L
L
G
F
V
V
Y
E
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
66.95
28%
139
- C2 -
-
5GHE
-
CR6AA_BACTU
A:
[167-295]
---------------------------------------------------------------------------
N
I
V
D
--
N
N
--
S
D
-
D
D
A
I
A
K
--
A
I
K
-----
D
F
-
K
A
R
-
C
G
I
L
I
K
E
A
K
Q
-------
Y
E
-
E
A
A
K
--
N
I
V
T
S
L
D
Q
F
L
H
G
D
Q
K
K
L
E
G
V
I
N
I
Q
K
R
L
K
E
V
Q
T
A
L
N
Q
A
H
G
E
S
S
P
A
H
K
E
L
L
E
K
V
-
K
N
L
K
T
T
L
E
R
T
I
K
A
E
Q
D
L
E
K
K
V
E
Y
S
F
L
L
G
P
L
L
G
F
V
V
Y
E
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
65.30
25%
20
- C2 -
-
3VVE
1
?
A:
[144-242]
-------------------------------
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--
K
I
P
G
I
K
E
V
R
T
Y
Q
R
D
-
P
D
A
L
Q
--
D
----
L
L
A
G
R
--
I
D
T
W
I
T
-
D
R
F
V
A
K
E
-
A
I
K
-----
E
R
-
K
L
E
-
N
T
L
Q
V
----------------------
G
E
L
V
F
Q
---
E
R
V
A
M
A
V
A
K
G
N
K
------
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
------
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
64.43
25%
27
- C2 -
-
3VVD
1
?
A:
[144-242]
-------------------------------
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--
K
I
P
G
I
K
E
V
R
T
Y
Q
R
D
-
P
D
A
L
Q
--
D
----
L
L
A
G
R
--
I
D
TW
I
T
-
D
R
F
V
A
K
E
-
A
I
K
-----
E
R
-
K
L
E
-
N
T
L
Q
V
----------------------
G
E
L
V
F
Q
---
E
R
V
A
M
A
V
A
K
G
N
K
------
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
------
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
64.42
25%
22
- C2 -
-
3VV5
1
?
A:
[144-242]
-------------------------------
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--
K
I
P
G
I
K
E
V
R
T
Y
Q
R
D
-
P
D
A
L
Q
--
D
----
L
L
A
G
R
--
I
D
T
W
I
T
-
D
R
F
V
A
K
E
-
A
I
K
-----
E
R
-
K
L
E
-
N
T
L
Q
V
----------------------
G
E
L
V
F
Q
---
E
R
V
A
M
A
V
A
K
G
N
K
------
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
------
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
62.56
9%
-159
- C2 -
-
5DO7
-
ABCG8_HUMAN
B:
[472-675]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
-----------
P
G
---
L
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
F
Y
--
L
A
-
G
G
F
M
I
N
L
S
S
L
-
W
T
V
P
A
W
I
S
K
V
S
F
L
R
W
C
F
E
G
L
M
K
I
Q
F
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
V
M
ELD
S
--------------------------------
Y
-----------------------
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
S
Q
D
W
------------
23
HHSearch
62.32
9%
-173
- C2 -
-
5DO7
-
ABCG8_HUMAN
D:
[472-671]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
-----------
P
G
---
L
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
F
Y
--
L
A
-
G
G
F
M
I
N
L
S
S
L
-
W
T
V
P
A
W
I
S
K
V
S
F
L
R
W
C
F
E
G
L
M
K
I
Q
F
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
M
ELD
S
--------------------------------
Y
-----------------------
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
----------------
4
PsiBlast_PDB
56.94
33%
-33
* C3 *
-
5FFI
1
FESII_AZOVI
A:
[11-78]
---------------------------------------------
M
P
H
N
K
K
V
Q
A
V
A
G
K
R
S
T
-
L
L
G
V
A
--
Q
----
E
N
G
V
K
IP
F
E
--
C
Q
-
D
G
N
C
G
S
C
-
L
V
K
I
T
HLD
G
E
-
R
I
K
-
G
M
L
L
T
D
K
E
R
N
-------
V
L
-
K
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
56.79
33%
-34
- C3 -
-
5FRT
1
FESII_AZOVI
A:
[11-78]
---------------------------------------------
M
P
H
N
K
K
V
Q
A
V
A
G
K
R
S
T
-
L
L
G
V
A
--
Q
----
E
N
G
V
K
IP
F
E
--
C
Q
-
D
G
N
C
G
S
C
-
L
V
K
I
T
H
LD
G
E
-
R
I
K
-
G
M
L
L
T
D
K
E
R
N
-------
V
L
-
K
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
55.35
9%
-168
- C2 -
-
5NJ3
1
?
A:
[451-663]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
A
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
F
M
L
G
L
K
P
-----------
K
---
A
D
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
M
M
--
I
F
-
S
G
L
L
V
N
L
T
T
I
A
S
-
W
L
S
W
L
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
H
N
E
F
L
G
Q
N
------------------------
F
CPGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
GIDLS
P
W
-----------------------
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
-----------------
24
HHSearch
55.11
9%
-168
- C2 -
-
5NJG
1
?
B:
[451-663]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
A
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
F
M
L
G
L
K
P
-----------
K
---
A
D
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
M
M
--
I
F
-
S
G
L
L
V
N
L
T
T
I
A
S
-
W
L
S
W
L
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
H
N
E
F
L
G
Q
N
------------------------
F
CPGLNATGNNPCNYATCTGEEYLVKQGIDLSP
W
-----------------------
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
-----------------
42
Fugue
54.36
16%
-
- C2 -
-
5MC9
-
C:
[10-62]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
K
V
S
D
L
E
S
------
E
A
R
-
K
Q
E
A
A
I
M
D
Y
N
R
D
I
A
E
I
I
K
D
I
H
N
L
E
D
I
K
K
T
L
P
T
G
C
F
N
T
P
S
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
52.90
9%
-165
- C2 -
-
5DO7
-
ABCG5_HUMAN
C:
[438-649]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
N
L
F
P
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
W
T
L
G
L
H
P
-----------
E
---
V
A
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
--
L
V
G
S
G
F
L
R
N
I
Q
E
M
-
P
I
P
F
K
I
I
S
Y
F
T
F
Q
K
Y
C
S
E
I
L
V
V
N
E
F
Y
G
L
N
------------------------
F
--------------------------------
T
CGSMCAFTQ
G
I
Q
F
I
E
K
TCPGATS
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
----------------
30
HHSearch
50.90
21%
90
- C2 -
-
3CNI
-
?
A:
[11-109]
-------------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
T
I
A
E
L
A
E
--
K
A
L
G
N
M
V
D
I
V
--
Y
A
--
G
S
-
D
L
K
E
A
E
E
-
A
V
K
-----
K
E
-
K
A
P
-
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
E
K
A
-
R
L
E
I
V
W
Y
L
R
G
T
G
L
S
E
-
A
V
S
T
G
T
I
S
S
L
I
E
------
S
L
K
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
50.56
9%
-166
- C2 -
-
5DO7
-
ABCG5_HUMAN
A:
[438-650]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
N
L
F
P
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
W
T
L
G
L
H
P
-----------
E
---
V
A
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
--
L
V
G
S
G
F
L
R
N
I
Q
E
M
-
P
I
P
F
K
I
I
S
Y
F
T
F
Q
K
Y
C
S
E
I
L
V
V
N
E
F
Y
G
L
N
------------------------
F
--------------------------------
T
CAFTQ
G
I
Q
F
I
E
K
TCPGATS----
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
S
---------------
28
HHSearch
47.78
8%
87
- C2 -
-
2P0S
2
?
B:
[8-125]
-----------------------------------------------
D
M
K
T
I
A
I
A
D
R
T
G
E
Y
-
E
Q
L
F
K
EN
D
----
E
F
R
F
V
---
H
--
A
E
K
T
A
E
E
Y
R
K
M
G
A
D
-----
K
S
-
G
I
D
-
A
V
L
E
I
R
Q
D
L
L
E------
D
P
N
A
V
A
I
--
Y
G
Y
K
Q
L
P
---
A
S
V
S
N
H
I
S
R
I
L
S
------
D
Y
L
S
D
K
K
I
A
S
Y
N
I
P
D
I-----
K
Q
I
L
A
D
S
K
I
E
L
S
V
H
T
Y
K
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
47.52
18%
249
- C2 -
-
1IC2
-
TPM1_CHICK
A:
[1-79]
-------------------------------------------------------------------------------------
M
D
-
A
I
K
K
K
M
Q
-
M
L
K
-----
L
D
-
K
E
N
-
A
L
D
R
A
E
Q
A
E
A
-------
D
K
-
K
A
A
E
--
E
R
S
K
Q
L
E
---
D
E
L
V
-
A
L
Q
K
K
L
K
------
G
T
E
D
E
L
D
K
Y
S
E
S
L
K
D
------
A
Q
E
-
K
L
E
L
A
D
K
K
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
47.24
22%
22
- C2 -
-
2FSI
-
SECA_ECOLI
A:
[767-828]
-------------------------------------------------------------------------------------
W
K
-
E
H
L
A
A
M
D
-
Y
L
R
-----
Q
G
I
H
L
R
-
G
Y
A
Q
K
D
P
K
Q
E
-------
Y
K
-
R
E
S
F
--
S
M
F
A
A
M
L
---
E
S
L
K
Y
E
V
I
S
T
L
S
------
K
V
Q
V
R
M
P
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
46.93
26%
35
- C1 -
-
4H3S
1
SYQ_YEAST
A:
[737-806]
--------------------------------------------
S
V
M
E
H
N
F
G
D
V
V
K
N
S
P
W
V
-
V
D
S
V
K
--
N
----
S
E
-----
F
Y
--
V
E
-
E
D
K
D
S
K
E
-
V
C
R
-----
F
Q
-
A
M
R
V
G
Y
F
T
L
D
K
E
S
T
-------
T
S
-
K
V
I
L
--
N
R
I
V
S
L
K
---
D
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------