@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1686: (2018-01-17 )
MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLSIMSRLTKKDRGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPYSRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDEPLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGRTDQIMQADLLSQLYEIPITLADINDKKICIYS
Atome Classification :
(22 SA)
.........10...----.....20.......-----.30........40........50........60-------........-70...----.....--80......-..90........100.-......110.......120--.........---130..----.....140.......150-----...-------.....160.......170.......180.......190.......200.......210.......220.......230.......240.......250
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
L
E
N
I
D
K
S
I
Q
K
Q
D
----
I
L
QGISLEV
S
P
Q
K
L
-----
T
A
F
IGPNGA
G
K
S
T
L
L
S
I
M
S
R
L
T
KKDR
G
V
L
S
IKG-------REIESW
N
S
-
Q
E
L
A
Q
----
E
L
T
I
L
--
K
Q
KINYQA-KL
T
V
E
E
L
V
S
FGRFPYS-RGRLR
S
E
D
W
E
K
I
R
E
T
L
N
----
Y
L
E
LTNL
K
D
---
R
Y
I
NS----LSGG
Q
L
Q
R
V
F
I
A
M
V
LAQ------DT
D
-------
F
I
L
LDEPLNN
L
D
I
K
Q
S
V
S
M
M
Q
I
L
R
R
L
V
E
E
LG
K
T
I
I
I
V
L
HDI
N
M
A
S
Q
Y
A
D
E
I
V
AFKDG
Q
V
FSKGRT
D
Q
I
M
Q
A
D
L
L
S
Q
L
Y
EI
P
I
T
L
ADINDK
K
I
C
I
YS
74
HHSearch
74.11
32%
-145
* C1 *
-
3RLF
2
MALK_ECOLI
A:
[4-222]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
---
P
A
E
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
K
L
A
G
-
A
--
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
----
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
---------------------------
73
HHSearch
71.82
32%
-137
- C1 -
-
2AWN
1
MALK_ECOLI
B:
[4-222]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
---
P
A
E
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
K
L
A
G
-
A
--
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
----
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
---------------------------
31
PsiBlast_CBE
68.79
33%
-51
- C1 -
-
3PUZ
1
MALK_ECOLI
B:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
QVAE
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
15
PsiBlast_PDB
68.35
28%
-62
- C1 -
-
4FI3
2
BTUD_ECOLI
C:
[5-246]
M
Q
L
Q
D
V
A
E
S
T
R
--------
L
G
P
L
S
G
E
V
R
A
G
E
I
-----
L
H
L
V
G
P
N
G
A
G
K
S
T
L
L
A
R
M
A
G
M
T
S
-
G
K
G
S
I
Q
F
A
G
-------
Q
P
L
E
A
W
S
A
-
T
K
L
A
L
----
H
R
A
Y
L
--
S
Q
Q
Q
T
P
P
F
-
A
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
-
R
T
E
L
-------
L
N
D
V
A
G
----
A
L
A
L
D
D
K
L
G
---
R
S
T
N
Q
----
L
S
G
G
E
W
Q
R
V
R
L
A
A
V
V
L
Q
------
I
T
P
QANPAGQ
L
L
L
L
D
Q
P
M
C
S
L
D
V
A
Q
Q
S
A
L
D
K
I
L
S
A
L
S
Q
Q
-
G
L
A
I
V
M
S
S
H
D
L
N
H
T
L
R
H
A
H
R
A
W
L
L
K
G
G
K
M
L
A
S
G
R
R
E
E
V
L
T
P
P
N
L
A
Q
A
Y
G
M
N
F
R
R
L
D
I
E
G
H
R
M
L
I
--
30
PsiBlast_CBE
66.85
33%
-51
- C1 -
-
3RLF
2
MALK_ECOLI
A:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
16
PsiBlast_PDB
66.70
28%
-62
- C1 -
-
4R9U
2
BTUD_ECOLI
C:
[5-246]
M
Q
L
Q
D
V
A
E
S
T
R
--------
L
G
P
L
S
G
E
V
R
A
G
E
I
-----
L
H
L
V
G
P
N
G
A
G
K
S
T
L
L
A
R
M
A
G
M
T
S
-
G
K
G
S
I
Q
F
A
G
-------
Q
P
L
E
A
W
S
A
-
T
K
L
A
L
----
H
R
A
Y
L
--
S
Q
Q
Q
T
P
P
F
-
A
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
-
R
T
E
L
-------
L
N
D
V
A
G
----
A
L
A
L
D
D
K
L
G
---
R
S
T
N
Q
----
L
S
G
G
E
W
Q
R
V
R
L
A
A
V
V
L
Q
------
I
T
P
QANPAGQ
L
L
L
L
D
Q
P
M
C
S
L
D
V
A
Q
Q
S
A
L
D
K
I
L
S
A
L
S
Q
Q
-
G
L
A
I
V
M
S
S
H
D
L
N
H
T
L
R
H
A
H
R
A
W
L
L
K
G
G
K
M
L
A
S
G
R
R
E
E
V
L
T
P
P
N
L
A
Q
A
Y
G
M
N
F
R
R
L
D
I
E
G
H
R
M
L
I
--
10
PsiBlast_PDB
66.51
32%
-52
- C1 -
-
2IT1
-
?
A:
[4-221]
I
K
L
E
N
I
V
K
K
F
G
N
F
T
----
A
L
N
N
I
N
L
K
I
K
D
G
E
F
-----
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
-------
K
D
V
T
E
L
P
P
-
K
D
--
R
----
N
V
G
L
V
--
F
Q
N
W
A
L
Y
P
-
H
M
T
V
Y
K
N
I
A
F
---
P
L
E
L
R
K
A
P
R
E
E
I
D
K
K
V
R
E
V
A
K
----
M
L
H
I
D
K
L
L
N
---
R
Y
P
W
Q
----
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
------
E
P
E
-------
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
----------------------------
42
PsiBlast_CBE
66.17
33%
-51
- C1 -
-
2AWO
1
MALK_ECOLI
B:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
QVAE
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
28
PsiBlast_CBE
65.76
33%
-52
- C1 -
-
4KI0
3
MALK_ECOLI
A:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
39
PsiBlast_CBE
65.34
33%
-50
- C1 -
-
3PUV
2
MALK_ECOLI
B:
[4-227]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
12
PsiBlast_PDB
64.94
28%
-52
- C1 -
-
4DBL
-
BTUD_ECOLI
C:
[5-246]
M
Q
L
Q
D
V
A
E
S
T
R
--------
L
G
P
L
S
G
E
V
R
A
G
E
I
-----
L
H
L
V
G
P
N
G
A
G
K
S
T
L
L
A
R
M
A
G
M
T
S
-
G
K
G
S
I
Q
F
A
G
-------
Q
P
L
E
A
W
S
A
-
T
K
L
A
L
----
H
R
A
Y
L
--
S
Q
Q
Q
T
P
P
F
-
A
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
-
R
T
E
L
-------
L
N
D
V
A
G
----
A
L
A
L
D
D
K
L
G
---
R
S
T
N
Q
----
L
S
G
G
E
W
Q
R
V
R
L
A
A
V
V
L
Q
------
I
T
P
QANPAGQ
L
L
L
L
D
Q
P
M
N
S
L
D
V
A
Q
Q
S
A
L
D
K
I
L
S
A
L
S
Q
Q
-
G
L
A
I
V
M
S
S
H
D
L
N
H
T
L
R
H
A
H
R
A
W
L
L
K
G
G
K
M
L
A
S
G
R
R
E
E
V
L
T
P
P
N
L
A
Q
A
Y
G
M
N
F
R
R
L
D
I
E
G
H
R
M
L
I
--
40
PsiBlast_CBE
64.93
33%
-56
- C1 -
-
3PUV
2
MALK_ECOLI
A:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
27
PsiBlast_CBE
64.64
33%
-51
- C1 -
-
4KI0
2
MALK_ECOLI
B:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
QVAE
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
36
PsiBlast_CBE
64.58
33%
-55
- C1 -
-
3PUX
2
MALK_ECOLI
A:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
32
PsiBlast_CBE
64.53
33%
-48
- C1 -
-
3PUZ
1
MALK_ECOLI
A:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
29
PsiBlast_CBE
64.45
33%
-50
- C1 -
-
3RLF
2
MALK_ECOLI
B:
[4-218]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
QVAE
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
1
PsiBlast_PDB
64.29
29%
-68
- C1 -
-
4G1U
-
HMUV_YERPE
C:
[12-246]
L
E
A
S
H
L
H
Y
H
V
Q
Q
Q
A
----
L
I
N
D
V
S
L
H
I
A
S
G
E
M
-----
V
A
I
I
G
P
N
G
A
G
K
S
T
L
L
R
L
L
T
G
Y
L
S
P
S
H
G
E
C
H
L
L
G
-------
Q
N
L
N
S
W
Q
P
-
K
A
L
A
R
----
T
R
A
V
M
--
R
Q
Y
S
E
L
A
F
-
P
F
S
V
S
E
V
I
Q
M
G
R
A
P
Y
G
-----
G
S
Q
D
R
Q
A
L
Q
Q
V
M
A
----
Q
T
D
C
L
A
L
A
Q
---
R
D
Y
R
V
----
L
S
G
G
E
Q
Q
R
V
Q
L
A
R
V
L
A
Q
L
WQPQP
T
P
R
-------
W
L
F
L
D
E
P
T
S
A
L
D
L
Y
H
Q
Q
H
T
L
R
L
L
R
Q
L
T
R
Q
E
P
L
A
V
C
C
V
L
H
D
L
N
L
A
A
L
Y
A
D
R
I
M
L
L
A
Q
G
K
L
V
A
C
G
T
P
E
E
V
L
N
A
E
T
L
T
Q
W
Y
Q
-----------------
38
PsiBlast_CBE
64.25
33%
-55
- C1 -
-
3PUW
2
MALK_ECOLI
A:
[4-217]
V
Q
L
Q
N
V
T
K
A
W
G
E
V
V
----
V
S
K
D
I
N
L
D
I
H
E
G
E
F
-----
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
-------
K
R
M
N
D
T
P
P
-
A
E
--
R
----
G
V
G
M
V
--
F
Q
S
Y
A
L
Y
P
-
H
L
S
V
A
E
N
M
S
F
G
L
-------
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
Q
L
A
H
L
L
D
---
R
K
P
K
A
----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
------
E
P
S
-------
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
--------------------------------
5
PsiBlast_PDB
64.16
33%
44
- C1 -
-
3TIF
4
Y796_METJA
A:
[2-223]
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
-----
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
-------
I
K
T
N
D
L
D
D
-
D
E
L
T
K
I
R
R
D
K
I
G
F
V
--
F
Q
Q
F
N
L
I
P
-
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
Y
-
R
G
A
M
S
G
E
--
E
R
R
K
R
A
L
E
----
C
L
K
M
A
E
L
E
E
---
R
F
A
N
H
KPNQ
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
------
N
P
P
-------
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-------------------------------------
3
PsiBlast_PDB
64.13
32%
-23
- C1 -
-
4U02
-
?
A:
[5-225]
I
R
I
R
N
L
H
K
W
F
G
P
L
H
----
V
L
K
G
I
H
L
E
V
A
P
G
E
K
-----
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
-------
L
S
V
K
D
D
R
A
L
R
E
I
R
R
----
E
V
G
M
V
--
F
Q
Q
F
N
L
F
P
-
H
M
T
V
L
E
N
V
T
L
A
--
P
M
R
-
V
R
R
W
P
R
E
K
A
E
K
--
K
A
L
E
----
L
L
E
R
V
G
I
L
D
QAR
K
Y
P
A
Q
----
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
------
E
P
K
-------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
----------------------------
17
PsiBlast_PDB
51.63
30%
-13
- C1 -
-
5X40
2
CBIO_RHOCB
A:
[36-241]
----------------------
L
S
L
A
V
P
K
G
E
S
-----
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
G
T
A
T
G
H
S
R
K
D
L
T
G
W
R
------
R
----
R
V
G
L
V
--
L
Q
D
A
D
D
Q
L
F
A
T
T
V
F
E
D
V
S
F
G
--
P
L
N
-
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
----
A
L
S
I
S
D
L
R
D
---
R
P
T
H
M
----
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
------
R
P
E
-------
V
L
L
L
D
Q
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
R
G
L
-
R
A
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
R
V
L
A
E
G
A
A
E
A
V
L
S
--------------------------
58
PsiBlast_CBE
34.47
31%
29
- C1 -
-
3J15
1
?
B:
[358-541]
------------------------
L
E
V
E
P
G
E
I
R
K
G
E
V
I
G
I
V
G
P
N
G
I
G
K
T
T
F
V
K
M
L
A
G
V
E
E
P
T
E
G
K
V
E
---------------
W
D
------------
L
T
V
A
Y
K
P
Q
Y
I
K
A
E
Y
-
E
G
T
V
Y
E
L
L
S
----
K
I
D
-
S
S
K
L
N
S
N
F
Y
K
T
--
E
L
L
K
----
P
L
G
I
I
D
L
Y
D
---
R
N
V
E
D
----
L
S
G
G
E
L
Q
R
V
A
I
A
A
T
L
L
R
------
D
A
D
-------
I
Y
L
L
D
E
P
S
A
Y
L
D
V
E
Q
R
L
A
V
S
R
A
I
R
H
L
M
E
K
N
E
K
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
R
L
I
V
F
-
E
G
E
P
G
R
H
G
R
A
-------------------------------