@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1701: (2018-01-17 )
MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCPECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSRLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYDLAKQLRFQISRLRLKQSPRLFHSRMLKSFLIAFTLYNILAVP
Atome Classification :
(20 SA)
.........10......--------..20..--------------......30........40..----..----------....50.-.......60........70........80..----.....------------.-90------.-.......100-....-------...110.---...--.--------..120.......130....---------...140.......150---........-----------------.160....-..----------------------------.170.-......-180-........190...---------------------....200.....-...210-----..--------------......220.......230--------.....-------...240-......----...250------------------.......260
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
E
Q
L
H
F
I
T
K
L
LDIKDP
N
--------
I
Q
I
L
D
I--------------INKD
T
H
K
E
I
I
A
K
LDYDAPS
C
----
P
E
----------
C
G
N
Q
L
K
K-YDFQKPSKIP
Y
L
ETTGM
P
T
R
I
L
L
R
K
R
R
F
K
C
Y
----HCSK
M
------------
M
-
V
A
------
E
-
T
S
I
VKKNHQ
I
-
P
R
I
I
-------
N
Q
K
I
A
Q
K
---
L
I
E
--
K
--------
I
S
M
T
D
I
A
H
Q
LSI
S
T
S
T
V
I
R
---------
K
L
N
D
F
H
F
K
H
D
F
S
R
L
-----
P
E
I
MSW
D
E
-----------------YAFTK
G
K
M
-
S
F
----------------------------
I
A
Q
D
F-NN
L
N
I
I
-
T
V
--LEG
R
T
Q
A
I
I
R
N
H
F
L
---------------------
R
Y
D
R
V
-
V
R
C
R
V
K
-
I
I
T
M
D
------MF--------------S
P
Y
Y
D
L
A
K
Q
L
R
F
Q
I
S
R
L
R
---------LKQS
P
-------
R
L
F
H
---
S
R
M
L
K
S
----
F
L
I
A
F
T
------------------
L
Y
N
I
LAVP
21
Fugue
64.97
15%
-2
* C5 *
-
1GC1
11
?
G:
[12-321]
T
E
N
F
N
M
W
K
N
D
M
-----------------------------------
V
E
Q
M
H
E
D
I
I
S
L
W
D
Q
S
L
K
P
C
----
V
K
LTPLCVGAGS
C
N
T
S
V
I
T
-
Q
A
C
P
K
V
S
F
E
P
I
P
I
H
Y
C
A
P
A
G
F
A
I
L
K
C
N
N
K
T
F
NGTG
P
C
T
N
V
------------
S
-
T
V
------
Q
C
T
H
G
I
R
P
V
V
S
T
-
Q
L
L
L
-------
N
G
S
L
A
E
E
EV-
V
I
R
--
S
--------
V
N
F
T
D
N
A
K
T
I
I
V
Q
L
N
T
S
V
E
INCTGAGHC
N
I
S
R
A
K
W
N
N
T
L
K
Q
I
ASKLR
E
Q
F
G
N
N
K
T
-----------------
I
I
F
K
Q
S
S
G
-
G
D
----------------------------
P
E
I
V
T
-
H
S
F
N
C
G
G
E
F
--
F
Y
C
N
S
T
Q
L
F
N
S
T
W
F
---------------------
G
S
D
T
I
T
L
P
C
R
I
K
Q
I
I
N
M
W
QKVGKA
M
Y
--------------
A
P
P
I
S
G
Q
I
R
C
S
S
N
I
T
G
L
L
---------
L
T
R
D
G
GNSNNES
E
I
F
R
PGG
G
D
M
R
D
N
----
W
R
S
E
L
Y
------------------
K
Y
K
V
V
K
I
E
29
Fugue
61.64
19%
13
- C1 -
-
3J9Q
-
?
A:
[2-386]
S
F
F
H
G
V
T
V
T
N
V
D
I
G
A
R
T
IALPASSV
I
G
L
C
D
V
--------------
F
T
P
G
A
Q
A
S
A
K
P
N
V
P
V
L
L
T
S
K
----
K
D
----------
A
A
A
A
F
G
I
G
S
S
I
Y
L
A
C
E
A
I
Y
N
R
A
Q
A
V
I
V
A
V
G
V
E
T
A
E
T
P
E
A
----
Q
A
S
A
V
I
GGISAAGERTG
L
-
Q
A
------
L
-
L
D
G
K
S
R
F
N
A
Q
-
P
R
L
L
V
A
P
GHSA
Q
Q
A
V
A
T
A
M
D
G
L
A
E
--
K
--------
L
R
A
I
A
I
L
D
G
P
N
S
T
D
E
A
A
V
A
---------
Y
A
K
N
F
G
S
K
R
L
F
M
V
D
-----
P
G
V
Q
V
W
D
S
ATN
A
A
R
N
A
PA
S
A
Y
A
A
G
L
F
A
W
T
D
A
E
Y
-
G
F
WSSPSNKEIKGVTGTS
R
P
V
E
F
L
D
GDETC
R
A
N
L
L
-
N
N
A
N
I
A
-
T
I
--
I
R
D
D
G
Y
R
L
W
G
N
R
T
L
SSDS-----------------
K
W
A
F
V
-
T
R
V
R
T
M
-
D
L
V
M
D
------
A
I
L
A
G
H
K
WAVDRGITK
T
Y
V
K
D
V
T
E
G
L
R
A
F
M
R
D
L
K
N
Q
GAVI
N
F
E
V
Y
A
D
P
-------
D
L
N
S
---
A
S
Q
L
A
Q
G
K
V
Y
W
N
I
R
F
T
D
VPPAENPNFRVEVTDQW
L
T
E
V
L
D
V
A
23
Fugue
61.26
18%
-2
- C5 -
-
1G9M
15
?
G:
[5-321]
E
V
V
L
V
N
V
T
E
N
F
N
M
W
K
--------------
N
D
--------------
M
V
E
Q
M
H
E
D
I
I
S
L
W
D
Q
S
L
K
P
C
VKLT
P
L
----------
C
V
G
A
G
S
C
-
N
T
S
V
I
T
Q
A
C
P
K
V
S
F
E
P
I
P
I
H
-
Y
C
A
P
A
G
F
A
I
L
----
K
C
N
N
K
------------
T
-
F
N
GTGPCT
N
-
V
S
T
V
Q
C
T
H
G
I
R
P
V
V
S
-------
T
Q
L
L
L
N
G
---
S
L
A
--
E
--------
E
E
V
V
I
R
S
V
N
F
T
D
N
A
K
T
I
I
V
---------
Q
L
N
T
S
V
E
I
N
C
T
G
A
G
-----
H
C
N
I
S
R
A
K
-----------------
W
N
N
T
L
K
Q
I
A
S
K
----------------------------
L
R
E
Q
F
-
G
N
N
K
T
I
-
I
F
KQ
S
S
G
G
D
P
E
I
V
T
H
S
F
N
CGGEFFYCNSTQLFNSTWFNG
S
D
T
I
T
-
L
P
C
R
I
K
Q
I
I
N
M
W
QKVGKA
M
Y
--------------
A
P
P
I
S
G
Q
I
R
C
S
S
N
I
T
G
L
L
---------
L
T
R
D
G
GNSNNES
E
I
F
R
PGG
G
D
M
R
D
N
----
W
R
S
E
L
Y
------------------
K
Y
K
V
V
K
I
E
39
HHSearch
56.82
27%
-255
* C3 *
-
1PDN
2
PRD_DROME
C:
[16-59]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
L
-
P
N
N
I
-------
R
L
K
I
V
E
M
---
A
A
D
--
G
--------
I
R
P
C
V
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
---------
I
L
N
R
Y
Q
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
55.18
21%
-238
- C3 -
-
6PAX
-
PAX6_HUMAN
A:
[17-59]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
-
P
D
S
T
-------
R
Q
R
I
V
E
L
---
A
H
S
--
G
--------
A
R
P
C
D
I
S
R
I
L
Q
V
S
N
G
C
V
S
K
---------
I
L
G
R
Y
Y
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.12
59%
-207
- C3 -
-
5CY1
-
TNR3_ECOLX
A:
[160-181]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
T
E
I
A
H
Q
L
S
I
A
R
S
T
V
Y
K
---------
I
L
E
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
47.37
30%
-161
- C3 -
-
2IU5
-
DHAS_LACLA
A:
[5-56]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
-------
T
Q
K
I
I
A
K
---
A
F
K
--
D
--------
L
M
Q
S
N
A
Y
H
Q
I
S
V
S
D
I
M
Q
T
A
---------
K
I
R
R
Q
T
F
Y
N
Y
F
Q
N
Q
-----
E
E
L
L
S
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
46.84
59%
-217
- C3 -
-
5CY2
-
TNR3_ECOLX
A:
[160-181]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
T
E
I
A
H
Q
L
S
I
A
R
S
T
V
Y
K
---------
I
L
E
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
45.14
12%
-120
- C3 -
-
2ELH
-
DAN_DROME
A:
[23-64]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
T
P
R
D
-------
K
I
H
A
I
Q
R
---
I
H
D
--
G
--------
E
S
K
A
S
V
A
R
D
I
G
V
P
E
S
T
L
R
G
---------
W
C
K
N
E
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
43.58
29%
-29
- C4 -
-
3LGM
1
HDOX2_STAAN
A:
[37-103]
--
Q
Q
M
F
V
T
K
T
L
N
T
E
D
T
D
E
-------
V
K
I
L
T
I
W
ES
E
D
S
F
N
N
W
L
N
S
D
V
F
K
E
A
H
K
N
V
R
L
K
S
D
D
D
G
Q
Q
S
----
P
I
----------
L
S
N
K
V
F
K
-
Y
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
43.17
29%
-19
* C4 *
-
3LGN
2
HDOX2_STAAN
A:
[37-103]
--
Q
Q
M
F
V
T
K
T
L
N
T
E
D
T
D
E
-------
V
K
I
L
T
I
W
ES
E
D
S
F
N
N
W
L
N
S
D
V
F
K
E
A
H
K
N
V
R
L
K
S
D
D
D
G
Q
Q
S
----
P
I
----------
L
S
N
K
V
F
K
-
Y
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
42.69
29%
0
- C4 -
-
2ZDP
1
HDOX2_STAAN
A:
[37-103]
--
Q
Q
M
F
V
T
K
T
L
N
T
E
D
T
D
E
-------
V
K
I
L
T
I
W
ES
E
D
S
F
N
N
W
L
N
S
D
V
F
K
E
A
H
K
N
V
R
L
K
S
D
D
D
G
Q
Q
S
----
P
I
----------
L
S
N
K
V
F
K
-
Y
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
42.33
12%
-27
- C3 -
-
2RN7
-
?
A:
[6-56]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
R
F
-
S
P
E
V
-------
R
Q
R
A
V
R
M
---
V
L
E
--
S
Q
G
E
Y
DS
Q
W
A
T
I
C
S
I
A
P
K
I
G
C
T
P
E
T
L
R
V
---------
W
V
R
Q
H
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
41.49
22%
-56
- C3 -
-
1TD6
-
Y330_MYCPN
A:
[112-201]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
E
L
----------------------------
V
L
Q
D
Y
P
N
K
L
N
M
I
-
H
Y
--
L
L
P
K
T
K
A
F
V
K
P
H
L
L
---------------------
Q
R
L
Q
F
-
V
L
T
D
S
E
-
L
L
E
L
K
------
R
F
--------------
S
F
F
Q
A
L
N
Q
I
P
G
F
Q
G
E
Q
V
----------------------
E
Y
F
N
---
S
K
L
K
Q
K
----
F
T
L
T
L
G
------------------
E
F
E
I
A
Q
Q
P
17
PsiBlast_PDB
37.97
29%
-31
- C4 -
-
1SQE
-
HDOX2_STAAM
A:
[51-117]
--
Q
Q
M
F
V
T
K
T
L
N
T
E
D
T
D
E
-------
V
K
I
L
T
I
W
ES
E
D
S
F
N
N
W
L
N
S
D
V
F
K
E
A
H
--------
D
D
G
Q
Q
S
----
P
I
----------
L
S
N
K
V
F
K
-
Y
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
37.19
14%
27
- C3 -
-
2JN6
-
?
A:
[5-49]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
-
S
E
E
F
-------
K
R
D
A
V
A
L
---
Y
E
N
SD
G
--------
A
S
L
Q
Q
I
A
N
D
L
G
I
N
R
V
T
L
K
N
---------
W
I
I
K
Y
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
36.25
18%
-155
- C2 -
-
5K2M
-
?
E:
[2-34]
--------------------------------------------------------------
V
E
C
----
P
V
----------
C
G
S
E
I
E
I
-
G
E
V
-------------------
E
L
H
Q
I
V
E
C
P
----
V
C
G
A
E
------------
L
-
E
V
------
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
35.88
12%
-46
- C2 -
-
5LJ3
-
SLT11_YEAST
N:
[6-324]
N
E
P
P
P
N
I
C
E
Q
C
L
G
D
E
A
N
--------
I
R
M
T
K
I
--------------
P
Q
G
S
E
--------------
C
----
K
I
----------
C
T
L
P
F
T
L
-
Y
H
F
K
T
S
K
R
S
N
N
I
I
K
T
L
I
------------
C
V
----
R
C
A
T
Q
------------
R
N
I
C
------
Q
-
C
C
M
L
D
S
R
W
H
I
-
P
----------------------------------
I
Q
L
R
D
H
L
I
S
L
V
V
M
T
E
E
A
K
N
---------
D
M
M
K
R
F
L
S
L
K
N
V
K
L
-----
G
G
----
A
Q
-----------------
I
T
S
D
P
S
E
A
-
D
N
----------------------------
I
V
D
K
L
-
K
N
I
L
L
S
-
F
F
--
L
Y
N
S
I
P
E
W
K
I
T
D
T
V
---------------------
S
Q
L
L
S
-
L
I
V
N
H
K
-
A
K
C
G
G
------
L
R
--------------
F
Q
S
S
E
L
G
E
R
F
V
S
K
I
F
I
I
P
---------
W
S
T
A
E
-------
N
I
K
L
---
S
L
S
L
N
K
----
L
I
Q
L
E
L
--------------------------
37
HHSearch
35.76
18%
-165
* C2 *
-
5K2M
-
?
F:
[2-34]
--------------------------------------------------------------
V
E
C
----
P
V
----------
C
G
S
E
I
E
I
-
G
E
V
-------------------
E
L
H
Q
I
V
E
C
P
----
V
C
G
A
E
------------
L
-
E
V
------
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
35.19
24%
-77
- C2 -
-
3WWN
-
?
B:
[3-35]
--------------------------------------------------------------
G
T
C
----
P
E
----------
C
G
A
E
L
R
L
-
E
N
P
-------------------
E
L
G
E
L
V
V
C
E
----
D
C
G
A
E
------------
L
-
E
V
------
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------