@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1734: (2018-01-18 )
MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDENFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYDVSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRIDGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHHFIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQKAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNSQFTEDEAEE
Atome Classification :
(38 SA)
.........10........20........30........40........50........60.------.......70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200-........210.......220.......-230...-.-....240.......250....-...260.......270.......280.--......290.......300.......310.......320...-.-...330.......340.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
G
F
L
L
M
G
A
L
F
I
V
L
P
R
T
M
V
S
A
K
R
I
N
Q
V
L
D
L
H
S
SIQN
P
V
Q
V
Q
LTDENFKG
Q
V
E
F
K
D
V
T
F
R
YAAN------
S
E
A
V
I
E
H
V
S
F
KAETG
Q
T
V
A
F
IGSTGS
G
K
S
T
L
V
N
L
I
P
R
F
YDVSAG
E
I
L
V
DGVNVQDYDFSATAHAG
Q
K
V
A
I
V
GPTGA
G
K
T
T
I
V
N
L
L
M
K
F
Y
EIDKG
S
I
R
I
DGVDT
K
A
M
T
R
S
E
V
H
D
A
F
S
M
V
L
Q
DT
W
L
FEGTIRDN
L
I
Y
NQI-G-I
S
D
E
R
M
M
E
A
S
K
AVG
I
H
H
F
I
M
TLPD
G
Y
D
T
-IL-DD
T
-
V
-
T
L
SVG
Q
K
Q
L
L
T
I
A
C
A
L
LKD
A
S
-
L
L
I
L
DEATSSVD
T
R
T
E
E
L
I
Q
K
A
M
D
R
L
M--EGR
T
S
F
V
I
A
H
R
L
S
TIRNA
D
L
I
L
V
MKDG
N
I
IEQG
N
Y
E
E
L
M
AQG-G-
F
Y
A
D
L
YNSQFTEDEAEE
129
HHSearch
82.14
48%
-87
- C1 -
-
3QF4
1
Y288_THEMA
B:
[313-590]
-----
L
S
N
Q
F
N
M
I
Q
M
A
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
V
E
--
L
R
E
V
R
G
E
I
E
F
K
N
V
W
F
S
Y
D
K
-------
K
K
P
V
L
K
D
I
T
F
H
I
K
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
--------------------------------------------------
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
-
T
D
N
G
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
S
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
--------
1
PsiBlast_PDB
80.03
42%
-90
* C1 *
-
3QF4
1
Y288_THEMA
B:
[324-591]
----------------
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
V
E
L
R
E
--
V
R
G
E
I
E
F
K
N
V
W
F
S
Y
D
-
K
------
K
K
P
V
L
K
D
I
T
F
H
I
K
--------------------------------------------------
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
T
D
N
G
-
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
S
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
Y
-------
2
PsiBlast_PDB
79.77
42%
-91
- C1 -
-
4Q4A
1
Y288_THEMA
B:
[324-591]
----------------
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
V
E
L
R
E
--
V
R
G
E
I
E
F
K
N
V
W
F
S
Y
D
-
K
------
K
K
P
V
L
K
D
I
T
F
H
I
K
--------------------------------------------------
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
T
D
N
G
-
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
S
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
Y
-------
4
PsiBlast_PDB
78.72
41%
-83
- C1 -
-
4Q4J
-
Y288_THEMA
B:
[324-591]
----------------
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
V
E
L
R
E
--
V
R
G
E
I
E
F
K
N
V
W
F
S
Y
D
-
K
------
K
K
P
V
L
K
D
I
T
F
H
I
K
--------------------------------------------------
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
T
D
N
G
-
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
C
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
Y
-------
128
HHSearch
77.02
48%
-
- C1 -
-
4Q4H
-
Y288_THEMA
B:
[313-590]
-----
L
S
N
Q
F
N
M
I
Q
M
A
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
V
E
--
L
R
E
V
R
G
E
I
E
F
K
N
V
W
F
S
Y
D
K
-------
K
K
P
V
L
K
D
I
T
F
H
I
K
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
--------------------------------------------------
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
-
T
D
N
G
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
S
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
--------
7
PsiBlast_PDB
76.35
38%
-62
- C1 -
-
5MKK
-
?
A:
[319-598]
---------------
A
M
A
S
A
E
R
I
F
G
V
L
D
T
E
E
E
L
K
D
P
-
E
D
P
T
P
I
R
G
F
R
G
E
V
E
F
R
D
V
W
L
A
Y
T
-------------------------------------------
P
K
G
V
E
P
T
E
K
D
W
V
L
K
G
V
S
F
R
-------
V
R
P
G
E
K
V
A
L
V
G
A
T
G
A
G
K
T
S
V
V
S
L
I
A
R
F
Y
D
P
Q
R
G
C
V
F
L
D
G
V
D
V
R
R
Y
R
Q
E
E
L
R
R
H
V
G
I
V
L
Q
E
P
F
L
F
S
G
T
V
L
D
N
L
R
L
F
D
P
-
S
-
V
P
P
E
R
V
E
E
V
A
R
F
L
G
A
H
E
F
I
L
R
L
P
K
G
Y
Q
T
-
V
L
-
G
E
R
G
A
-
G
L
S
T
G
E
K
Q
L
L
A
L
V
R
A
L
L
A
S
P
D
I
L
L
I
L
D
E
A
T
A
S
V
D
S
E
T
E
K
R
L
Q
E
A
L
Y
K
A
M
--
E
G
R
T
S
L
I
I
A
H
R
L
S
T
I
R
H
V
D
R
I
L
V
F
R
K
G
R
L
V
E
E
G
S
H
E
E
L
L
A
K
G
-
G
-
Y
Y
A
A
L
Y
R
L
Q
F
Q
E
-----
5
PsiBlast_PDB
72.16
53%
-92
- C1 -
-
4Q7L
-
Y288_THEMA
A:
[23-241]
----------------------------------------------------------------------------------------------------------------------------
D
I
T
F
H
I
K
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
T
D
N
G
-
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
S
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
Y
-------
118
HHSearch
71.29
40%
-75
- C1 -
-
4A82
-
Y1866_STAAM
B:
[297-574]
-----
L
V
A
S
F
T
T
L
T
Q
S
F
A
S
M
D
R
V
F
Q
L
I
D
E
D
Y
D
I
K
N
G
V
G
-
A
Q
P
I
E
I
K
Q
G
R
I
D
I
D
H
V
S
F
Q
Y
N
D
N
------
E
A
P
I
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
--------------------------------------------------
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
D
T
V
K
E
N
I
L
L
G
R
P
-
T
-
A
T
D
E
E
V
V
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
-
E
V
-
G
E
R
-
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
-
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
A
D
K
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
I
A
K
Q
-
G
-
A
Y
E
H
L
Y
S
----------
24
PsiBlast_CBE
71.09
39%
-95
- C1 -
-
5EUM
1
?
B:
[12-257]
-------------------------------------------
E
P
A
K
G
E
L
E
F
K
N
V
S
F
A
Y
Q
G
-------
E
E
L
A
L
N
N
I
S
F
S
V
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
N
L
V
T
R
F
Y
D
I
E
Q
G
E
I
L
L
D
G
V
N
I
Q
D
Y
R
L
S
--------------------------------------------------
N
L
R
E
N
C
A
V
V
S
Q
Q
V
H
L
F
N
D
T
I
A
N
N
I
A
Y
--
D
-
K
-
Y
S
R
E
E
I
I
A
A
A
K
A
A
Y
A
L
E
F
I
E
K
L
P
Q
G
F
D
T
-
V
I
G
E
N
G
-
A
-
S
L
S
G
G
Q
R
Q
R
L
A
I
A
R
A
L
L
R
N
S
P
-
V
L
I
L
D
E
A
T
----
T
E
S
E
R
A
I
Q
S
A
L
E
E
L
K
--
K
D
R
T
V
V
V
I
A
H
R
L
S
T
I
E
N
A
D
E
I
L
V
I
D
H
G
E
I
R
E
R
G
N
H
K
T
L
L
E
Q
N
-
G
-
A
Y
K
Q
L
H
S
M
Q
F
T
------
126
HHSearch
69.71
43%
-11
- C1 -
-
5MKK
-
?
A:
[309-590]
-----
L
S
D
K
F
N
L
F
Q
G
A
M
A
S
A
E
R
I
F
G
V
L
D
T
E
E
E
L
K
D
P
E
D
-
P
T
P
I
R
G
F
R
G
E
V
E
F
R
D
V
W
L
A
Y
T
P
K
GVEPTE
K
D
W
V
L
K
G
V
S
F
R
V
R
P
G
E
K
V
A
L
V
G
A
T
G
A
--------------------------------------------------
G
K
T
S
V
V
S
L
I
A
R
F
Y
D
P
Q
R
G
C
V
F
L
D
G
V
D
V
R
R
Y
R
Q
E
E
L
R
R
H
V
G
I
V
L
Q
E
P
F
L
F
S
G
T
V
L
D
N
L
R
L
F
D
P
-
S
-
V
P
P
E
R
V
E
E
V
A
R
F
L
G
A
H
E
F
I
L
R
L
P
K
G
Y
Q
T
-
V
L
-
G
E
R
G
A
-
G
L
S
T
G
E
K
Q
L
L
A
L
V
R
A
L
L
A
S
P
D
I
L
L
I
L
D
E
A
T
A
S
V
D
S
E
T
E
K
R
L
Q
E
A
L
Y
K
A
M
--
E
G
R
T
S
L
I
I
A
H
R
L
S
T
I
R
H
V
D
R
I
L
V
F
R
K
G
R
L
V
E
E
G
S
H
E
E
L
L
A
K
G
-
G
-
Y
Y
A
A
-------------
3
PsiBlast_PDB
67.32
42%
-
- C1 -
-
4Q4H
-
Y288_THEMA
B:
[324-591]
----------------
L
A
S
A
E
R
I
F
E
I
L
D
L
E
E
E
K
D
D
P
D
A
V
E
L
R
E
--
V
R
G
E
I
E
F
K
N
V
W
F
S
Y
D
-
K
------
K
K
P
V
L
K
D
I
T
F
H
I
K
--------------------------------------------------
P
G
Q
K
V
A
L
V
G
P
T
G
S
G
K
T
T
I
V
N
L
L
M
R
F
Y
D
V
D
R
G
Q
I
L
V
D
G
I
D
I
R
K
I
K
R
S
S
L
R
S
S
I
G
I
V
L
Q
D
T
I
L
F
S
T
T
V
K
E
N
L
K
Y
G
N
P
-
G
-
A
T
D
E
E
I
K
E
A
A
K
L
T
H
S
D
H
F
I
K
H
L
P
E
G
Y
E
T
-
V
L
T
D
N
G
-
E
-
D
L
S
Q
G
Q
R
Q
L
L
A
I
T
R
A
F
L
A
N
P
K
-
I
L
I
L
D
E
A
T
S
N
V
D
T
K
T
E
K
S
I
Q
A
A
M
W
K
L
M
--
E
G
K
T
S
I
I
I
A
H
R
L
N
T
I
K
N
A
D
L
I
I
V
L
R
D
G
E
I
V
E
M
G
K
H
D
E
L
I
Q
K
R
-
G
-
F
Y
Y
E
L
F
T
S
Q
Y
-------
12
PsiBlast_PDB
66.18
44%
-93
- C1 -
-
3NH9
3
A:
[72-292]
----------------------------------------------------------------------------------------------------------------------------
D
V
S
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
G
A
G
K
S
T
I
L
R
L
L
F
R
F
Y
D
I
S
S
G
C
I
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
R
S
H
I
G
V
V
P
Q
D
T
V
L
F
N
D
T
I
A
D
N
I
R
Y
G
R
V
-
T
-
A
G
N
D
E
V
E
A
A
A
Q
A
A
G
I
H
D
A
I
M
A
F
P
E
G
Y
R
T
Q
V
G
-
E
R
G
-
L
-
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
I
L
K
A
P
G
-
I
I
L
L
D
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
S
L
A
K
V
C
--
A
N
R
T
T
I
V
V
A
H
R
L
S
T
V
V
N
A
D
Q
I
L
V
I
K
D
G
C
I
V
E
R
G
R
H
E
A
L
L
S
R
G
-
G
-
V
Y
A
D
M
W
Q
L
Q
Q
G
Q
-----
14
PsiBlast_PDB
66.06
44%
-98
- C1 -
-
3NHB
2
A:
[72-292]
----------------------------------------------------------------------------------------------------------------------------
D
V
S
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
G
A
G
K
S
T
I
L
R
L
L
F
R
F
Y
D
I
S
S
G
C
I
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
R
S
H
I
G
V
V
P
Q
D
T
V
L
F
N
D
T
I
A
D
N
I
R
Y
G
R
V
-
T
-
A
G
N
D
E
V
E
A
A
A
Q
A
A
G
I
H
D
A
I
M
A
F
P
E
G
Y
R
T
Q
V
G
-
E
R
G
-
L
-
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
I
L
K
A
P
G
-
I
I
L
L
D
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
S
L
A
K
V
C
--
A
N
R
T
T
I
V
V
A
H
R
L
S
T
V
V
N
A
D
Q
I
L
V
I
K
D
G
C
I
V
E
R
G
R
H
E
A
L
L
S
R
G
-
G
-
V
Y
A
D
M
W
Q
L
Q
Q
G
Q
-----
11
PsiBlast_PDB
65.91
44%
-91
- C1 -
-
3NH6
2
A:
[72-292]
----------------------------------------------------------------------------------------------------------------------------
D
V
S
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
G
A
G
K
S
T
I
L
R
L
L
F
R
F
Y
D
I
S
S
G
C
I
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
R
S
H
I
G
V
V
P
Q
D
T
V
L
F
N
D
T
I
A
D
N
I
R
Y
G
R
V
-
T
-
A
G
N
D
E
V
E
A
A
A
Q
A
A
G
I
H
D
A
I
M
A
F
P
E
G
Y
R
T
Q
V
G
-
E
R
G
-
L
-
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
I
L
K
A
P
G
-
I
I
L
L
D
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
S
L
A
K
V
C
--
A
N
R
T
T
I
V
V
A
H
R
L
S
T
V
V
N
A
D
Q
I
L
V
I
K
D
G
C
I
V
E
R
G
R
H
E
A
L
L
S
R
G
-
G
-
V
Y
A
D
M
W
Q
L
Q
Q
G
Q
-----
13
PsiBlast_PDB
65.70
44%
-97
- C1 -
-
3NHA
3
A:
[72-292]
----------------------------------------------------------------------------------------------------------------------------
D
V
S
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
G
A
G
K
S
T
I
L
R
L
L
F
R
F
Y
D
I
S
S
G
C
I
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
R
S
H
I
G
V
V
P
Q
D
T
V
L
F
N
D
T
I
A
D
N
I
R
Y
G
R
V
-
T
-
A
G
N
D
E
V
E
A
A
A
Q
A
A
G
I
H
D
A
I
M
A
F
P
E
G
Y
R
T
Q
V
G
-
E
R
G
-
L
-
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
I
L
K
A
P
G
-
I
I
L
L
D
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
S
L
A
K
V
C
--
A
N
R
T
T
I
V
V
A
H
R
L
S
T
V
V
N
A
D
Q
I
L
V
I
K
D
G
C
I
V
E
R
G
R
H
E
A
L
L
S
R
G
-
G
-
V
Y
A
D
M
W
Q
L
Q
Q
G
Q
-----
120
HHSearch
65.31
35%
-75
- C1 -
-
4MRP
2
ATM1_NOVAD
A:
[318-595]
-----
L
G
M
V
Y
R
T
I
R
Q
G
L
I
D
M
A
E
M
F
R
L
I
D
T
H
I
E
V
A
D
V
P
N
-
A
P
A
L
V
V
N
R
P
S
V
T
F
D
N
V
V
F
G
Y
D
R
-------
D
R
E
I
L
H
G
L
S
F
E
V
A
A
G
S
R
V
A
I
V
G
P
S
G
A
G
K
S
T
I
A
R
--------------------------------------------------
L
L
F
R
F
Y
D
P
W
E
G
R
I
L
I
D
G
Q
D
I
A
H
V
T
Q
T
S
L
R
A
A
L
G
I
V
P
Q
D
S
V
L
F
N
D
T
I
G
Y
N
I
A
Y
G
R
D
-
G
-
A
S
R
A
E
V
D
A
A
A
K
G
A
A
I
A
D
F
I
A
R
L
P
Q
G
Y
D
T
-
E
V
-
G
E
R
G
L
-
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
L
V
K
N
P
P
-
I
L
L
F
D
E
A
T
S
A
L
D
T
R
T
E
Q
D
I
L
S
T
M
R
A
V
A
--
S
H
R
T
T
I
S
I
A
H
R
L
S
T
I
A
D
S
D
T
I
L
V
L
D
Q
G
R
L
A
E
Q
G
S
H
L
D
L
L
R
R
D
-
G
-
L
Y
A
E
M
W
A
R
---------
121
HHSearch
65.27
35%
-76
- C1 -
-
4MRS
2
ATM1_NOVAD
B:
[318-595]
-----
L
G
M
V
Y
R
T
I
R
Q
G
L
I
D
M
A
E
M
F
R
L
I
D
T
H
I
E
V
A
D
V
P
N
-
A
P
A
L
V
V
N
R
P
S
V
T
F
D
N
V
V
F
G
Y
D
R
-------
D
R
E
I
L
H
G
L
S
F
E
V
A
A
G
S
R
V
A
I
V
G
P
S
G
A
G
K
S
T
I
A
R
--------------------------------------------------
L
L
F
R
F
Y
D
P
W
E
G
R
I
L
I
D
G
Q
D
I
A
H
V
T
Q
T
S
L
R
A
A
L
G
I
V
P
Q
D
S
V
L
F
N
D
T
I
G
Y
N
I
A
Y
G
R
D
-
G
-
A
S
R
A
E
V
D
A
A
A
K
G
A
A
I
A
D
F
I
A
R
L
P
Q
G
Y
D
T
-
E
V
-
G
E
R
G
L
-
K
L
S
G
G
E
K
Q
R
V
A
I
A
R
T
L
V
K
N
P
P
-
I
L
L
F
D
E
A
T
S
A
L
D
T
R
T
E
Q
D
I
L
S
T
M
R
A
V
A
--
S
H
R
T
T
I
S
I
A
H
R
L
S
T
I
A
D
S
D
T
I
L
V
L
D
Q
G
R
L
A
E
Q
G
S
H
L
D
L
L
R
R
D
-
G
-
L
Y
A
E
M
W
A
R
---------
116
HHSearch
64.80
34%
-64
- C1 -
-
4MYC
-
ATM1_YEAST
C:
[392-679]
-----
L
G
S
V
Y
R
D
L
K
Q
S
L
I
D
M
E
T
L
F
K
L
R
K
N
E
V
K
I
K
N
A
E
R
P
L
M
L
P
E
N
V
P
Y
D
I
T
F
E
N
V
T
F
G
Y
H
P
-------
D
R
K
I
L
K
N
A
S
F
T
I
P
A
G
W
K
T
A
I
V
G
S
S
G
S
G
K
S
T
I
L
K
L
--------------------------------------------------
V
F
R
F
Y
D
P
E
S
G
R
I
L
I
N
G
R
D
I
K
E
Y
D
I
D
A
L
R
K
V
I
G
V
V
P
Q
D
T
P
L
F
N
D
T
I
W
E
N
V
K
F
G
R
I
-
D
-
A
T
D
E
E
V
I
T
V
V
E
K
A
Q
L
A
P
L
I
K
K
L
P
Q
G
F
D
T
-
I
V
-
G
E
R
-
G
L
M
I
S
G
G
E
K
Q
R
L
A
I
A
R
V
L
L
K
N
A
R
-
I
M
F
F
D
E
A
T
S
A
L
D
T
H
T
E
Q
A
L
L
R
T
I
R
D
N
F
TS
G
S
R
T
S
V
Y
I
A
H
R
L
R
T
I
A
D
A
D
K
I
I
V
L
D
N
G
R
V
R
E
E
G
K
H
L
E
L
L
A
M
P
-
G
S
L
Y
R
E
L
W
T
I
Q
E
D
L
D
H
---
68
PsiBlast_CBE
64.60
42%
-96
- C1 -
-
4S0F
2
?
A:
[507-721]
----------------------------------------------------------------------------------------------------------------------------
N
I
N
L
T
I
P
K
G
K
T
V
A
I
V
G
E
S
G
S
G
K
T
T
L
A
K
L
L
M
N
F
Y
S
P
E
K
G
D
I
L
I
N
G
H
S
I
K
N
I
S
L
E
L
I
R
K
K
I
A
F
V
S
Q
D
V
F
I
F
S
G
T
V
K
E
N
L
C
L
G
N
E
-
N
-
V
D
M
D
E
I
I
K
A
A
K
M
A
N
A
H
D
F
I
E
K
L
P
L
K
Y
D
T
-
F
L
-
N
E
S
G
A
-
N
L
S
E
G
Q
K
Q
R
L
A
I
A
R
A
L
L
K
K
P
D
-
I
L
I
L
D
Q
A
T
S
N
L
D
S
I
T
E
N
H
I
K
D
A
I
Y
G
L
E
--
D
D
V
T
V
I
I
I
A
H
R
L
S
T
I
V
N
C
D
K
I
Y
L
L
K
D
G
E
I
V
E
S
G
S
H
T
E
L
I
A
L
K
-
G
-
C
Y
F
K
M
W
-----------
117
HHSearch
64.36
34%
-67
- C1 -
-
4MYC
-
ATM1_YEAST
B:
[392-679]
-----
L
G
S
V
Y
R
D
L
K
Q
S
L
I
D
M
E
T
L
F
K
L
R
K
N
E
V
K
I
K
N
A
E
R
P
L
M
L
P
E
N
V
P
Y
D
I
T
F
E
N
V
T
F
G
Y
H
P
-------
D
R
K
I
L
K
N
A
S
F
T
I
P
A
G
W
K
T
A
I
V
G
S
S
G
S
G
K
S
T
I
L
K
L
--------------------------------------------------
V
F
R
F
Y
D
P
E
S
G
R
I
L
I
N
G
R
D
I
K
E
Y
D
I
D
A
L
R
K
V
I
G
V
V
P
Q
D
T
P
L
F
N
D
T
I
W
E
N
V
K
F
G
R
I
-
D
-
A
T
D
E
E
V
I
T
V
V
E
K
A
Q
L
A
P
L
I
K
K
L
P
Q
G
F
D
T
-
I
V
-
G
E
R
-
G
L
M
I
S
G
G
E
K
Q
R
L
A
I
A
R
V
L
L
K
N
A
R
-
I
M
F
F
D
E
A
T
S
A
L
D
T
H
T
E
Q
A
L
L
R
T
I
R
D
N
F
TS
G
S
R
T
S
V
Y
I
A
H
R
L
R
T
I
A
D
A
D
K
I
I
V
L
D
N
G
R
V
R
E
E
G
K
H
L
E
L
L
A
M
P
-
G
S
L
Y
R
E
L
W
T
I
Q
E
D
L
D
H
---
67
PsiBlast_CBE
62.93
42%
-95
- C1 -
-
4S0F
2
?
B:
[507-721]
----------------------------------------------------------------------------------------------------------------------------
N
I
N
L
T
I
P
K
G
K
T
V
A
I
V
G
E
S
G
S
G
K
T
T
L
A
K
L
L
M
N
F
Y
S
P
E
K
G
D
I
L
I
N
G
H
S
I
K
N
I
S
L
E
L
I
R
K
K
I
A
F
V
S
Q
D
V
F
I
F
S
G
T
V
K
E
N
L
C
L
G
N
E
-
N
-
V
D
M
D
E
I
I
K
A
A
K
M
A
N
A
H
D
F
I
E
K
L
P
L
K
Y
D
T
-
F
L
-
N
E
S
G
A
-
N
L
S
E
G
Q
K
Q
R
L
A
I
A
R
A
L
L
K
K
P
D
-
I
L
I
L
D
Q
A
T
S
N
L
D
S
I
T
E
N
H
I
K
D
A
I
Y
G
L
E
--
D
D
V
T
V
I
I
I
A
H
R
L
S
T
I
V
N
C
D
K
I
Y
L
L
K
D
G
E
I
V
E
S
G
S
H
T
E
L
I
A
L
K
-
G
-
C
Y
F
K
M
W
-----------
66
PsiBlast_CBE
61.70
33%
-108
- C1 -
-
2PMK
1
A:
[4-241]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
85
PsiBlast_CBE
61.44
32%
-96
- C1 -
-
1XEF
2
HLYBP_ECOLX
A:
[2-239]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
78
PsiBlast_CBE
60.86
32%
-89
- C1 -
-
2FGJ
2
HLYBP_ECOLX
C:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
80
PsiBlast_CBE
60.56
32%
-87
- C1 -
-
2FGJ
2
HLYBP_ECOLX
A:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
75
PsiBlast_CBE
59.72
32%
-89
- C1 -
-
2FGK
2
HLYBP_ECOLX
A:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
74
PsiBlast_CBE
59.57
32%
-95
- C1 -
-
2FGK
2
HLYBP_ECOLX
B:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
73
PsiBlast_CBE
58.83
32%
-87
- C1 -
-
2FGK
2
HLYBP_ECOLX
C:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
72
PsiBlast_CBE
58.24
32%
-94
- C1 -
-
2FGK
2
D:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
77
PsiBlast_CBE
58.09
32%
-88
- C1 -
-
2FGJ
2
D:
[8-245]
-------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
P
D
------
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
---------------
G
H
D
L
A
L
A
D
P
N
-------------------------------
W
L
R
R
Q
V
----
G
V
V
L
Q
D
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
N
P
-
G
-
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
-
I
V
G
E
Q
G
-
A
-
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
-
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
-
L
Y
S
Y
L
Y
Q
L
Q
--------
91
PsiBlast_CBE
49.43
39%
-18
- C1 -
-
1MV5
1
LMRA_LACLA
A:
[20-240]
----------------------------------------------------------------------------------------------------------------------------
D
I
S
F
E
A
Q
P
N
S
I
I
A
F
A
G
P
S
G
G
G
K
S
T
I
F
S
L
L
E
R
F
Y
Q
P
T
A
G
E
I
T
I
D
G
Q
P
I
D
N
I
S
L
E
N
W
R
S
Q
I
G
F
V
S
Q
D
S
A
I
M
A
G
T
I
R
E
N
L
T
Y
G
L
E
-
G
D
Y
T
D
E
D
L
W
Q
V
L
D
L
A
F
A
R
S
F
V
E
N
M
P
D
Q
L
N
T
E
V
G
-
E
R
G
-
V
-
K
I
S
G
G
Q
R
Q
R
L
A
I
A
R
A
F
L
R
N
P
K
-
I
L
M
L
D
E
A
T
A
S
L
D
S
E
S
E
S
M
V
Q
K
A
L
D
S
L
M
--
K
G
R
T
T
L
V
I
A
H
R
L
S
T
I
V
D
A
D
K
I
Y
F
I
E
K
G
Q
I
T
G
S
G
K
H
N
E
L
V
A
T
H
-
P
-
L
Y
A
K
Y
V
S
E
Q
L
T
------
33
PsiBlast_CBE
47.60
38%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
A:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------
32
PsiBlast_CBE
47.60
38%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
B:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------
31
PsiBlast_CBE
47.60
38%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
C:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------
30
PsiBlast_CBE
47.60
38%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
D:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------
36
PsiBlast_CBE
47.57
38%
-
- C1 -
-
3B5Y
2
MSBA_SALTY
B:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------
35
PsiBlast_CBE
47.57
38%
-
- C1 -
-
3B5Y
2
MSBA_SALTY
C:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------
34
PsiBlast_CBE
47.57
38%
-
- C1 -
-
3B5Y
2
MSBA_SALTY
D:
[340-580]
-----------------------------------------------
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
------
E
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R
E
Y
----------------------------------------------
T
L
A
S
L
R
N
Q
V
----
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
-
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
D
N
G
L
D
T
-
I
I
G
E
N
G
-
V
-
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
-
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
--
K
N
R
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
H
-
G
-
V
Y
A
Q
L
H
K
M
Q
F
-------