@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1779: (2018-01-19 )
MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGHLLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70..---......80........90.......---.100.......110......--------..120---..--...---..130...--....140.......----------------------------------150...---....---160.......170.......180.......--------190-----..-----....------.200-----.....-..210....---.--....--220--.......230------------...------.....240----..-----...---.---.------------------250-------------.-------------.....-...260.......270..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MN
K
K
T
R
Q
T
L
I
G
L
L
V
L
L
L
LSTG
S
Y
Y
I
K
QMPSAPNSPKT
N
L
S
Q
K
K
Q
ASEA
P
S
Q
A
L
A
E
S
V
L
T
D
A
V
K
S
Q
IK
G
S
L
E
WN---G
S
G
A
F
I
VNGNKTNL
D
A
KVSSKPYAD---NKTKTVGK
E
T
V
P
T
-
V
A
N
A
L
L
--------
S
K
A
T
R
---
Q
Y
--KNR---KETGNGST--SWTPP
G
W
H
Q
V
K
NLK----------------------------------GSY
T
H
A---VDRG---
H
L
L
G
Y
A
L
IGGLDGFDASTSNP
K
N
I
A
V
Q
T
AW--------ANQ-----AQ-----AEYS------TG
Q
N
-----
Y
Y
E
S
K
-
V
R
K
--
A
LDQ---N--K
R
V
R
--
Y
R
V
--
T
L
Y
YASNED-------------LVP------S
A
S
QIEAK----SS-----DG
E
---
L
---
E
------------------
F
---------------
N
-------------
V
LVPN-VQK
G
L
Q
L
D
YRTG
E
V
T
VTQ
14
Fugue
85.52
99%
-21
- C4 -
-
3OWV
-
NUCE_STRPN
A:
[20-248]
---------------------------------------------
S
E
A
P
S
Q
A
L
A
E
S
V
L
T
D
A
V
K
S
Q
I
K
G
S
L
E
W
N
---
G
S
G
A
F
I
V
N
G
N
K
T
N
L
D
A
K
V
S
S
K
P
Y
A
D
---
N
K
T
K
T
V
G
K
E
T
V
P
T
-
V
A
N
A
L
L
--------
S
K
A
T
R
---
Q
----------------
Y
--
S
W
T
P
P
G
W
H
Q
V
K
N
L
K
----------------------------------
G
S
Y
T
H
A
---
V
D
R
G
---
A
L
L
G
Y
A
L
I
G
G
L
D
G
F
D
A
S
T
S
N
P
K
N
I
A
V
Q
T
A
W
--------
A
N
Q
-----
A
Q
-----
A
E
Y
S
------
T
G
Q
N
-----
Y
Y
E
S
K
-
V
R
K
--
A
L
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
L
Y
Y
A
S
N
E
D
-------------
L
V
P
------
S
A
S
Q
I
E
A
K
----
S
S
-----
D
G
E
---
L
---
E
------------------
F
---------------
N
-------------
V
L
V
P
N
-
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
Q
1
PsiBlast_PDB
85.13
99%
-21
- C4 -
-
3OWV
-
NUCE_STRPN
A:
[20-248]
---------------------------------------------
S
E
A
P
S
Q
A
L
A
E
S
V
L
T
D
A
V
K
S
Q
I
K
G
S
L
E
W
N
---
G
S
G
A
F
I
V
N
G
N
K
T
N
L
D
A
K
V
S
S
K
P
Y
A
D
---
N
K
T
K
T
V
G
K
E
T
V
P
T
-
V
A
N
A
L
L
--------
S
K
A
T
R
---
Q
Y
------------------
S
W
T
P
P
G
W
H
Q
V
K
N
L
K
----------------------------------
G
S
Y
T
H
A
---
V
D
R
G
---
A
L
L
G
Y
A
L
I
G
G
L
D
G
F
D
A
S
T
S
N
P
K
N
I
A
V
Q
T
A
W
--------
A
N
Q
-----
A
Q
-----
A
E
Y
S
------
T
G
Q
N
-----
Y
Y
E
S
K
-
V
R
K
--
A
L
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
L
Y
Y
A
S
N
E
D
-------------
L
V
P
------
S
A
S
Q
I
E
A
K
----
S
S
-----
D
G
E
---
L
---
E
------------------
F
---------------
N
-------------
V
L
V
P
N
-
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
Q
24
HHSearch
75.35
98%
50
- C4 -
-
3OWV
-
NUCE_STRPN
B:
[17-248]
------------------------------------------
K
Q
A
S
E
A
P
S
Q
A
L
A
E
S
V
L
T
D
A
V
K
S
Q
I
K
G
S
L
E
W
N
---
G
S
G
A
F
I
V
N
G
N
K
T
N
L
D
A
K
V
S
S
K
P
Y
A
D
N
K
T
K
T
V
---
G
K
E
T
V
P
T
-
V
A
N
A
L
L
--------
S
K
A
T
R
---
Q
Y
--
K
-----------
S
T
--
S
W
T
P
P
G
W
H
Q
V
K
N
L
K
----------------------------------
G
S
Y
T
H
A
---
V
D
R
G
---
A
L
L
G
Y
A
L
I
G
G
L
D
G
F
D
A
S
T
S
N
P
K
N
I
A
V
Q
T
A
W
--------
A
N
Q
-----
A
Q
-----
A
E
Y
S
------
T
G
Q
N
-----
Y
Y
E
S
K
-
V
R
K
--
A
L
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
L
Y
Y
A
S
N
E
D
-------------
L
V
P
------
S
A
S
Q
I
E
A
K
----
S
S
-----
D
G
E
---
L
---
E
------------------
F
---------------
N
-------------
V
L
V
P
N
-
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
Q
2
PsiBlast_PDB
65.01
51%
-33
- C4 -
-
4QGO
1
?
A:
[31-224]
-----------------------------------------------------------------------------
N
G
I
Y
E
L
N
N
N
Q
T
N
L
N
A
D
V
N
V
K
A
Y
V
Q
---
N
---
T
I
D
N
Q
Q
R
P
S
-
T
A
N
A
M
L
--------
D
R
T
I
R
---
Q
Y
--
Q
N
R
---
R
---------
N
W
K
P
L
G
W
H
Q
V
A
-
T
N
----------------------------------
D
H
Y
G
H
A
---
V
D
K
G
---
A
L
I
A
Y
A
L
A
G
N
F
K
G
W
D
A
S
V
S
N
P
Q
N
V
V
T
Q
T
A
H
--------
S
N
Q
-----
S
N
-----
Q
K
I
N
------
R
G
Q
N
-----
Y
Y
E
S
L
-
V
R
K
--
A
V
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
P
L
Y
R
N
D
T
D
-------------
L
V
P
------
F
A
M
H
L
E
A
K
----
S
Q
-----
D
G
T
---
L
---
E
------------------
F
---------------
N
-------------
V
A
I
P
N
-
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
--
13
PsiBlast_CBE
64.83
51%
-32
- C4 -
-
4QGO
1
?
B:
[31-224]
-----------------------------------------------------------------------------
N
G
I
Y
E
L
N
N
N
Q
T
N
L
N
A
D
V
N
V
K
A
Y
V
Q
---
N
---
T
I
D
N
Q
Q
R
P
S
-
T
A
N
A
M
L
--------
D
R
T
I
R
---
Q
Y
--
Q
N
R
---
R
---------
N
W
K
P
L
G
W
H
Q
V
A
-
T
N
----------------------------------
D
H
Y
G
H
A
---
V
D
K
G
---
A
L
I
A
Y
A
L
A
G
N
F
K
G
W
D
A
S
V
S
N
P
Q
N
V
V
T
Q
T
A
H
--------
S
N
Q
-----
S
N
-----
Q
K
I
N
------
R
G
Q
N
-----
Y
Y
E
S
L
-
V
R
K
--
A
V
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
P
L
Y
R
N
D
T
D
-------------
L
V
P
------
F
A
M
H
L
E
A
K
----
S
Q
-----
D
G
T
---
L
---
E
------------------
F
---------------
N
-------------
V
A
I
P
N
-
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
--
3
PsiBlast_PDB
64.24
51%
-24
- C4 -
-
4QH0
-
?
A:
[31-224]
-----------------------------------------------------------------------------
N
G
I
Y
E
L
N
N
N
Q
T
N
L
N
A
D
V
N
V
K
A
Y
V
Q
---
N
---
T
I
D
N
Q
Q
R
P
S
-
T
A
N
A
M
L
--------
D
R
T
I
R
---
Q
Y
--
Q
N
R
---
R
D
T
T
L
P
D
A
--
N
W
K
P
L
G
W
H
Q
V
A
-
T
N
----------------------------------
D
H
Y
G
H
A
---
V
D
K
G
---
A
L
I
A
Y
A
L
A
G
N
F
K
G
W
D
A
S
V
S
N
P
Q
N
V
V
T
Q
T
A
H
--------
S
N
Q
-----
S
N
-----
Q
K
I
N
------
R
G
Q
N
-----
Y
Y
E
S
L
-
V
R
K
--
A
V
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
P
L
Y
R
N
D
T
D
-------------
L
V
P
------
F
A
M
H
L
E
A
K
----
S
Q
-----
D
G
T
---
L
---
E
------------------
F
---------------
N
-------------
V
A
I
P
N
-
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
--
26
HHSearch
55.22
50%
55
- C4 -
-
4QH0
-
?
A:
[15-224]
----------------------------------------------------------
Q
N
N
L
K
N
A
I
G
-
N
L
P
F
Q
Y
--
V
N
G
I
Y
E
L
N
N
N
Q
T
N
L
N
A
D
V
N
V
K
A
Y
V
Q
---
N
T
I
---
D
N
Q
Q
R
P
S
-
T
A
N
A
M
L
--------
D
R
T
I
R
---
Q
Y
--
Q
N
R
---
R
D
T
T
L
P
D
A
--
N
W
K
P
L
G
W
H
Q
V
A
T
N
-----------------------------------
D
H
Y
G
H
A
---
V
D
K
G
---
A
L
I
A
Y
A
L
A
G
N
F
K
G
W
D
A
S
V
S
N
P
Q
N
V
V
T
Q
T
A
H
--------
S
N
Q
-----
S
N
-----
Q
K
I
N
------
R
G
Q
N
-----
Y
Y
E
S
L
-
V
R
K
--
A
V
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
P
L
Y
R
N
D
T
D
-------------
L
V
P
------
F
A
M
H
L
E
A
K
----
S
Q
-----
D
G
T
---
L
---
E
------------------
F
---------------
N
-------------
V
A
I
P
N
-
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
--
25
HHSearch
54.29
50%
55
- C4 -
-
4QGO
1
?
B:
[15-224]
----------------------------------------------------------
Q
N
N
L
K
N
A
I
G
-
N
L
P
F
Q
Y
--
V
N
G
I
Y
E
L
N
N
N
Q
T
N
L
N
A
D
V
N
V
K
A
Y
V
Q
---
N
T
I
---
D
N
Q
Q
R
P
S
-
T
A
N
A
M
L
--------
D
R
T
I
R
---
Q
Y
--
Q
N
R
---
R
---------
N
W
K
P
L
G
W
H
Q
V
A
T
N
-----------------------------------
D
H
Y
G
H
A
---
V
D
K
G
---
A
L
I
A
Y
A
L
A
G
N
F
K
G
W
D
A
S
V
S
N
P
Q
N
V
V
T
Q
T
A
H
--------
S
N
Q
-----
S
N
-----
Q
K
I
N
------
R
G
Q
N
-----
Y
Y
E
S
L
-
V
R
K
--
A
V
D
Q
---
N
--
K
R
V
R
--
Y
R
V
--
T
P
L
Y
R
N
D
T
D
-------------
L
V
P
------
F
A
M
H
L
E
A
K
----
S
Q
-----
D
G
T
---
L
---
E
------------------
F
---------------
N
-------------
V
A
I
P
N
-
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
--
27
HHSearch
42.68
24%
17
- C4 -
-
2XGR
8
?
A:
[43-250]
----------------------------------------------------------------------------
T
H
Y
K
N
T
V
S
S
K
L
L
P
F
T
A
N
-
Y
Q
--
L
Q
L
---
G
E
L
---
D
N
L
N
R
A
T
-
F
S
H
I
Q
L
--------
Q
D
R
H
E
---
T
K
--
D
V
R
---
T
K
-----
I
------------------------------------------------------
W
V
---
M
N
R
G
---
H
L
V
G
Y
Q
F
C
G
L
-------
N
D
E
P
R
N
L
V
A
M
T
A
W
--------
L
N
T
-----
G
A
YSGAN
D
S
N
P
------
E
G
M
L
-----
Y
Y
E
N
R
-
L
D
S
--
W
L
A
L
H
P-
D
--
F
W
L
D
--
Y
K
V
--
T
P
I
Y
S
G
N
-
E
-------------
V
V
P
------
R
Q
I
E
L
Q
Y
V
----
G
I
-----
D
S
S
G
E
L
L
---
T
------------------
I
R
LNSNK
E
S
I
D
ENG
V
T
T
-------------
V
I
L
E
N
-
S
A
P
N
I
N
L
D
Y
L
N
G
T
A
T
P
--
22
Fugue
39.83
14%
-57
- C4 -
-
3KYQ
1
YKT6_RAT
A:
[1-193]
--------
L
M
K
L
Y
S
L
S
V
F
Y
K
G
E
P
K
A
V
L
L
K
A
A
Y
D
V
S
S
F
S
F
F
Q
R
S
S
V
Q
E
F
M
T
F
T
S
Q
L
--
I
V
E
R
S
A
K
G
S
R
A
S
V
K
E
Q
---
E
Y
L
C
H
V
Y
V
R
S
D
S
L
A
G
V
V
I
A
D
S
E
Y
P
---------------
S
R
-
V
A
F
T
L
L
--------
E
K
V
L
D
---
E
F
--
S
K
Q
---
V
-------------------------------------------------------------------------------------
D
R
I
D
W
P
V
G
S
P
A
T
I
H
Y
T
A
L
--------
D
G
H
-----
L
S
-----
R
Y
Q
N
------
P
R
E
A
-----
D
P
M
S
K
-
V
Q
A
--
E
L
D
E
---
T
--
K
I
I
L
--
H
N
--------
T
M
E
S
-------------
L
L
E
------
R
G
E
K
L
D
D
L
----
V
S
-----
K
S
E
------------------------------------------------------------
V
-
L
G
T
Q
S
K
A
F
Y
K
T
A
R
K
Q
N
--
28
HHSearch
38.25
24%
70
- C4 -
-
5FGW
-
?
D:
[59-260]
------------------------------------------------------------------------------------------------
V
S
N
I
H
Y--
S
V
L
---
D
G
Y
G
R
S
G
-
E
A
Y
G
I
I
--------
T
K
D
M
I
---
D
M
SA
G
Y
R
---
E
K
W
---
E
S
--
K
P
E
P
S
G
W
Y
S
Y
F
F
K
N
TNQRATESDYKHSPKNVSKISNNIKASILLSNGN
V
R
N
G
Y
L
---
F
D
R
S
---
G
L
I
A
D
S
L
G
G
R
--------
P
F
R
N
N
L
I
T
G
T
R
T
--------
Q
N
V
-----
G
N
-----
N
D
R
K
------
G
G
M
Q
-----
Y
I
E
N
K
-
V
L
D
--
H
I
K
R
---
N
PK
V
H
V
Y
--
Y
K
A
--
T
P
V
Y
Q
G
S
-
E
-------------
L
L
P
------
R
A
V
L
V
S
A
L
----
S
S
-----
D
G
F
---
I
---
D
------------------
E
---------------
T
-------------
V
R
V
F
N
-
N
V
A
G
F
N
I
D
Y
Q
N
G
G
L
L
---
29
HHSearch
38.11
24%
73
- C4 -
-
5FGW
-
?
A:
[59-260]
------------------------------------------------------------------------------------------------
V
S
N
I
H
Y
--
S
V
L
---
D
G
Y
G
R
S
G
-
E
A
Y
G
I
I
--------
T
K
D
M
I
---
D
M
S
A
G
Y
R
---
E
K
W
---
E
S
--
K
P
E
P
S
G
W
Y
S
Y
F
F
K
N
TNQRAT
E
S
D
Y
K
H
SPKN
V
S
K
I
S
N
N
I
K
A
S--------
R
N
G
Y
L
---
F
D
R
S
---
G
L
I
A
D
S
L
G
G
R
--------
P
F
R
N
N
L
I
T
G
T
R
T
--------
Q
N
V
-----
G
N
-----
N
D
R
K
------
G
G
M
Q
-----
Y
I
E
N
K
-
V
L
D
--
H
I
K
R
---
N
PK
V
H
V
Y
--
Y
K
A
--
T
P
V
Y
Q
G
S
-
E
-------------
L
L
P
------
R
A
V
L
V
S
A
L
----
S
S
-----
D
G
F
---
I
---
D
------------------
E
---------------
T
-------------
V
R
V
F
N
-
N
V
A
G
F
N
I
D
Y
Q
N
G
G
L
L
---
15
Fugue
37.46
22%
34
- C4 -
-
2XGR
8
?
A:
[33-250]
---------------------------------------------------------------------
R
T
Y
P
---
N
V
S
H
A
N
T
H
Y
K
N
T
V
S
S
K
L
L
P
F
T
A
N
Y
Q
---
L
Q
L
G
E
L
D
N
L
N
R
A
T
-
F
S
H
I
Q
L
--------
Q
D
R
H
E
---
T
K
--
D
V
R
----------------
T
K
I
W
V
-------------------------------------------------
M
N
R
G
---
H
L
V
G
Y
Q
F
C
G
-------
L
N
D
E
P
R
N
L
V
A
M
T
A
W
--------
L
N
T
-----
G
A
-----
Y
S
G
A
------
N
D
S
N
PEG
M
L
Y
Y
E
N
R
-
L
D
S
--
W
L
A
L
H
P-
D
--
F
W
L
D
--
Y
K
V
--
T
P
I
Y
-
S
G
N
E
-------------
V
V
P
------
R
Q
I
E
L
Q
Y
V
----
G
I
-----
D
S
S
---
G
---
E
L
L
T
I
R
LNSNK
E
S
I
D
ENG
V
T
---------------
T
-------------
V
I
L
E
N
-
S
A
P
N
I
N
L
D
Y
L
N
G
T
A
T
P
--
7
PsiBlast_PDB
35.12
32%
22
- C4 -
-
5FGW
-
?
A:
[170-257]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
I
T
G
T
R
T
--------
Q
N
V
-----
G
N
-----
N
D
R
K
------
G
G
M
Q
-----
Y
I
E
N
K
-
V
L
D
--
H
I
K
R
---
N
--
P
K
V
H
VY
Y
K
A
--
T
P
V
Y
Q
G
S
E
--------------
L
L
P
------
R
A
V
L
V
S
A
L
----
S
S
-----
D
G
F
---
I
---
D
------------------
E
---------------
T
-------------
V
R
V
F
N
-
N
V
A
G
F
N
I
D
Y
Q
N
G
------
6
PsiBlast_PDB
33.56
32%
19
- C4 -
-
5FGU
2
A:
[377-518]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
I
T
G
T
R
T
--------
Q
N
V
-----
G
N
-----
N
D
R
K
------
G
G
M
Q
-----
Y
I
E
N
K
-
V
L
D
--
H
I
K
R
---
N
--
P
K
V
H
VY
Y
K
A
--
T
P
V
Y
Q
G
S
E
--------------
L
L
P
------
R
A
V
L
V
S
A
L
----
S
S
-----
D
G
F
---
I
---
D
------------------
E
---------------
T
-------------
V
R
V
F
N
-
N
V
A
G
F
N
I
D
Y
Q
N
G
------
4
PsiBlast_PDB
31.35
29%
81
- C4 -
-
2XGR
8
?
A:
[48-249]
------------------------------------------------------------------------------------------------------------
T
V
S
S
K
L
L
P
F
-
T
A
N
Y
Q
L
Q
L
G
E
LDNL
N
R
A
T
F
S
H
I
Q
L
--
Q
D
R
---
H
E
T
K
D
V
R
T
KI------------------------------------------------------W
V
-
M
N
R
G
---
H
L
V
G
Y
Q
F
C
G
L
N
D
-------
E
P
R
N
L
V
A
M
T
A
W
--------
L
N
T
GAYSG
A
N
-----
D
S
N
P
------
E
G
M
L
-----
Y
Y
E
N
R
-
L
D
S
W
L
A
L
H
P
---
D
--
F
W
L
D
--
Y
K
V
--
T
P
I
Y
S
G
N
E
--------------
V
V
P
--------
R
Q
I
E
L
Q
Y
V
G
I
D
S
-----
S
G
E
---
L
L
T
I
R
------------------
L
---------------
N
SNK
E
S
I
D
ENG
V
T
T
V
I
L
E
N
-
S
A
P
N
I
N
L
D
Y
L
N
G
T
A
T
---
23
Fugue
28.88
16%
40
- C3 -
-
4C9B
4
CWC22_HUMAN
B:
[8-291]
-------------
D
P
L
L
T
R
T
G
G
A
Y
I
P
P
A
K
L
R
M
K
N
S
L
A
Y
Q
R
M
S
W
E
A
L
K
K
S
I
N
G
L
I
N
K
V
N
I
S
N
I
S
I
I
I
Q
E
L
L
Q
E
N
IVR
G
R
G
L
L
S
R
S
V
L
Q
A
Q
S
A
S
P
I
F
T
H
V
Y
A
A
---
L
V
A
I
I
N
S
K
--
F
P
Q
-
I
G
E
L
I
L
--------
K
R
L
I
L
---
N
F
--
R
K
G
---
Y
R
R
N
D
-----------
K
Q
L
C
L
T
A
S
----------------------------------
K
F
V
A
H
L
---
I
N
Q
N
VAH
E
V
L
C
L
E
M
L
T
L
L
L
E
R
P
T
D
D
S
V
E
V
A
I
G
F
L
K
E
C
--------
G
L
K
-----
L
T
-----
Q
V
S
P
------
R
G
I
N
-----
A
I
F
E
R
-
L
R
N
--
I
L
H
E
SEI
D
--
K
R
V
Q
--
Y
M
I
--
E
V
M
F
A
V
R
K
D
GFKDHPIILEGLD
L
V
E
------
E
D
D
Q
F
T
H
M
----
L
P
LEDDY
N
P
E
---
D
---
V
------------------
L
---------------
N
-------------
V
F
K
M
D
P
N
F
M
E
N
E
E
K
Y
K
A
I
K
K
E
I
L
-
5
PsiBlast_PDB
28.71
29%
77
- C4 -
-
2XH3
-
?
A:
[48-249]
------------------------------------------------------------------------------------------------------------
T
V
S
S
K
L
L
P
F
-
T
A
N
Y
Q
L
Q
L
G
E
LDNL
N
R
A
T
F
S
H
I
Q
L
--
Q
D
R
---
H
E
T
------------------------------------------------------------
S
S
W
V
M
N
R
G
---
H
L
V
G
Y
Q
F
C
G
L
N
D
-------
E
P
R
N
L
V
A
M
T
A
W
LATGAYSG
A
N
D
-----
S
N
-----
P
E
---------
G
M
L
-----
Y
Y
E
N
R
-
L
D
S
W
L
A
L
H
P
---
D
--
F
W
L
D
--
Y
K
V
--
T
P
I
Y
S
G
N
E
--------------
V
V
P
--------
R
Q
I
E
L
Q
Y
V
G
I
D
S
-----
S
G
E
---
L
L
T
I
R
------------------
L
---------------
N
SNK
E
S
I
D
ENG
V
T
T
V
I
L
E
N
-
S
A
P
N
I
N
L
D
Y
L
N
G
T
A
T
---
18
Fugue
28.00
20%
15
- C4 -
-
5MJI
1
?
A:
[2-253]
----------
A
L
K
A
L
I
L
N
T
T
L
R
------
R
S
P
S
R
S
Q
T
Q
G
L
I
D
K
A
V
P
L
Y
E
K
E
G
I
E
T
E
V
V
R
--
V
I
D
H
D
I
E
Q
E
Y
-
W
D
---
D
Y
D
D
W
----
N
A
G
E
K
A
R
R
E
D
E
W
P
W
L
L
---
E
K
I
R
E
A
D
I
L
V
I
A
T
P
I
T
L
N
M
C
--------
T
S
A
A
H
---
V
I
--
L
E
K
L
N
L
M
D
E
L
N
G
D
T
--
K
Q
F
P
L
------------------------------------------------------
Y
N
---
K
V
A
G
L
L
M
C
G
N
E
D
G
A
H
H
V
A
G
T
V
L
N
N
L
G
R
L
G
Y
--------
S
V
P
-----
P
N
-----
A
A
A
Y
W
L
G
P
AG
T
G
P
G
-----
Y
I
E
G
K
-
G
D
R
--
H
F
H
T
---
N
--
K
L
I
R
--
F
M
V
A
N
T
S
H
L
A
R
M
L
Q
-------------
E
T
P
YTTD
L
E
A
C
A
Q
A
A
R
E
----
E
S
-----
D
D
V
---
F
---
A
------------------
I
---------------
R
-------------
V
N
V
N
T
-
P
A
I
R
Y
K
R
F
Q
K
L
G
E
V
K
V
E
E
46
HHSearch
27.19
10%
-36
- C4 -
-
4B56
-
ENPP1_MOUSE
A:
[628-697]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
---
L
S
Y
G
---
F
L
T
P
P
R
L
N
R
V
S
N
H
I
Y
S
E
A
L
L
T
S
N
I
V
P
M
Y
Q
S
--------
F
-
Q
-----
V
-----------------
I
W
H
-----
Y
L
H
D
T
L
L
Q
R
--
Y
A
H
E
---
R
--
N
G
I
N
--
V
V
S
--
G
P
V
F
D
F
D
------------------------------------------------------------------------------------------------------------------------------