@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1977: (2018-01-24 )
MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTTLIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYPRKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFILDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSPWRCFNVHENGQEVGHA
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10-....--..---..-20........30........40........50........60..-------....-----.-------.70........80..----.-----...---..-90.........----100.........110........120..-.....-----------130.......140.......150.......160.......170.......180.......190.......200.......210---.-..-----.....220.......230..----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
R
Y
I
T
V
E
D
L
S
F
-YYDK--
E
P
---
V
L
-
E
H
I
N
Y
CVDSG
E
F
V
T
L
TGENGA
A
K
T
T
L
I
K
A
S
LGILQPRI
G
K
V
A
I
S-------KTNT-----Q-------G
K
K
L
R
I
A
Y
L
P
Q
Q
I
A
S----F-----NAG---F
P
-
S
-
T
V
Y
E
F
V
KSG----R--YP
R
K
G
W
F
R
RLN-AH
D
E
E
H
I
K
A
S
L
D
S-VGM
W
E
-----------
H
R
D
K
RLGSLSG
G
Q
K
Q
R
A
V
I
A
R
M
FASDP
D
V
F
I
LDEPTTGMDAGS
K
N
E
F
Y
E
L
M
H
HSAHHHG
K
A
V
L
M
I
TH
D
P
E
E
V
K
D
YADR
N
I
H
L
----
V
-RN-----QDSP
W
R
C
F
NVHEN
G
Q
EVGHA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
80.39
31%
-1
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[3-218]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
L
H
I
G
H
L
S
K
-
S
F
Q
N
--
T
P
---
V
L
-
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
-------
G
K
T
I
-----
F
SKNTNLP
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
----------
F
-----
P
H
-
L
-
T
V
Y
R
N
I
A
Y
G
----
L
--
G
N
G
K
----
G
R
T
-
A
Q
E
R
Q
R
I
E
A
M
L
E
L
-
T
G
I
S
E
-----------
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
----
K
Q
G
R
-----
I
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
73.17
28%
21
- C1 -
-
3GFO
-
ECFA3_CLOP1
A:
[8-232]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
V
E
E
L
N
Y
N
Y
S
D
G
--
T
H
---
A
L
-
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
I
L
F
D
-------
N
K
P
I
-----
D
-------
Y
S
R
K
G
I
M
K
L
R
E
S
I
G
I
----
V
F
QDPD
N
Q
L
---
F
S
-
A
-
S
V
Y
Q
D
V
S
F
G
A
V
N
M
K
--
L
P
E
D
E
I
R
K
R
V
D
-
N
--------
A
L
K
R
-
T
G
I
E
H
-----------
L
K
D
K
P
T
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
V
E
M
Q
K
E
L
G
I
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
-
N
V
F
V
----
M
-
K
E
GRVIL
Q
G
N
P
K
E
V
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
69.91
29%
-25
- C1 -
-
2NQ2
-
Y1470_HAEIN
C:
[3-202]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
L
S
V
E
N
L
G
F
-
Y
Y
Q
A
--
E
N
---
F
L
F
Q
Q
L
N
F
D
L
N
K
G
D
I
L
A
V
L
G
Q
N
G
C
G
K
S
T
L
L
D
L
L
L
G
I
H
R
P
I
Q
G
K
I
E
V
Y
-------
Q
S
--------------------
I
G
F
V
P
Q
---
F
----
F
-----
S
S
P
---
F
A
-
Y
-
S
V
L
D
I
V
L
M
G
----
R
--
S
T
H
I
N
T
F
A
K
P
K
-
S
H
D
Y
Q
V
A
M
Q
A
L
D
Y
-
L
N
L
T
H
-----------
L
A
K
R
E
F
T
S
L
S
G
G
Q
R
Q
L
I
L
I
A
R
A
I
A
S
E
C
K
L
I
L
L
D
E
P
T
S
A
L
D
L
A
N
Q
D
I
V
L
S
L
L
I
D
L
A
Q
S
Q
N
M
T
V
V
F
T
T
H
Q
P
N
Q
V
V
A
I
A
N
K
T
L
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
68.73
28%
-11
- C1 -
-
4YMU
1
?
J:
[2-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
V
N
D
V
Y
K
-
N
F
G
S
--
L
E
---
V
L
-
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
-------
G
V
K
I
-----
N
-------
N
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
VFQH
F
-----
N
L
----
F
P
H
L
-
T
A
I
E
N
I
T
L
A
--------
P
V
K
--
V
K
K
M
N
-
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
DDGV
I
-
V
E
-----
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
68.60
29%
14
- C1 -
-
5X3X
-
CBIO_RHOCB
B:
[3-224]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
I
L
A
A
E
A
L
T
Y
-
A
F
P
G
G-
V
K
---
A
L
-
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
-------
G
T
A
T
-----
G
HSRKDLT
G
W
R
R
R
V
G
L
V
L
Q
D
A
D
D
----
Q
-----
L
-----
F
A
-
T
-
T
V
F
E
D
V
S
F
G
----
P
--
L
N
L
----
G
L
S
E
-
A
E
A
R
A
R
V
E
E
A
L
A
A
-
L
S
I
S
D
-----------
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
E
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
R
G
L
R
-
A
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
----
R
T
G
R
-----
V
L
A
E
G
A
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
68.56
24%
-47
- C1 -
-
4TQU
-
?
T:
[3-215]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
V
S
I
Q
N
V
V
K
-
R
Y
D
K
--
T
T
---
V
V
-
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
-------
G
R
V
I
-----
N
DLA----
P
K
D
R
D
V
A
M
V
F
Q
N
Y
A
L
----------
Y
-----
P
H
-
L
-
N
V
R
D
N
I
S
F
G
----
L
--
R
L
K
R
T
----
K
K
-
S
V
I
D
A
A
V
K
T
A
A
D
I
-
L
G
L
Q
P
-----------
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
----
R
D
G
L
-----
I
E
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
68.24
28%
-10
- C1 -
-
4YMS
-
?
J:
[2-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
V
N
D
V
Y
K
-
N
F
G
S
--
L
E
---
V
L
-
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
-------
G
V
K
I
-----
N
-------
N
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
VFQH
F
-----
N
L
----
F
P
H
L
-
T
A
I
E
N
I
T
L
A
--------
P
V
K
--
V
K
K
M
N
-
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
DDGV
I
-
V
E
-----
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
66.67
28%
-11
- C1 -
-
4YMT
-
?
J:
[2-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
V
N
D
V
Y
K
-
N
F
G
S
--
L
E
---
V
L
-
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
-------
G
V
K
I
-----
N
-------
N
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
VFQH
F
-----
N
L
----
F
P
H
L
-
T
A
I
E
N
I
T
L
A
--------
P
V
K
--
V
K
K
M
N
-
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
DDGV
I
-
V
E
-----
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
65.56
28%
-10
- C1 -
-
4YMW
-
?
J:
[2-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
V
N
D
V
Y
K
-
N
F
G
S
--
L
E
---
V
L
-
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
-------
G
V
K
I
-----
N
-------
N
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
VFQH
F
-----
N
L
----
F
P
H
L
-
T
A
I
E
N
I
T
L
A
--------
P
V
K
--
V
K
K
M
N
-
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
DDGV
I
-
V
E
-----
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
64.99
26%
-23
- C1 -
-
2YYZ
1
?
A:
[2-213]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
I
R
V
V
N
L
K
K
-
Y
F
G
K
--
V
K
---
A
V
-
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
-------
D
V
L
V
-----
N
DIP----
P
K
Y
R
E
V
G
M
V
F
Q
N
Y
A
L
----------
Y
-----
P
H
-
M
-
T
V
F
E
N
I
A
F
P
----
L
--
R
A
R
R
----
I
S
K
-
D
E
V
E
K
R
V
V
E
I
A
R
K
-
L
L
I
D
N
-----------
L
L
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
----
N
Q
G
K
-----
L
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
63.49
28%
-8
- C1 -
-
4YMV
1
?
J:
[2-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
V
N
D
V
Y
K
-
N
F
G
S
--
L
E
---
V
L
-
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
-------
G
V
K
I
-----
N
-------
N
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
VFQH
F
-----
N
L
----
F
P
H
L
-
T
A
I
E
N
I
T
L
A
--------
P
V
K
--
V
K
K
M
N
-
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
DDGV
I
-
V
E
-----
E
G
T
P
E
E
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
63.29
33%
16
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[10-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
K
-
S
F
Q
N
--
T
P
---
V
L
-
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
GKTIFSK
N
T
N
L
-----
P
-------
V
R
E
R
R
L
G
Y
L
V
Q
E
-------------
G
V
L
---
F
P
-
H
L
T
V
Y
R
N
I
A
Y
G
----
L
--
G
N
G
K
G
R
----
T
-
A
Q
E
R
Q
R
I
E
A
M
L
E
L
-
T
G
I
S
E
-----------
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
62.17
30%
43
- C1 -
-
4F4C
3
PGP1_CAEEL
A:
[4-1306]
N
G
S
L
R
Q
S
L
R
T
L
D
S
F
SLA
P
E
D
V
L
K
T
A
I
K
T
V
E
D
Y
EGDNIDSNG
E
I
K
I
TRDEVV
N
K
V
S
I
P
Q
L
Y
RYTT
T
L
E
K
L
L
L
F
I
G
T
L
V
A
V
I
T
G
A
G
L
P
L
M
S
I
L
Q
G
K
V
S
Q
A
F
I
N
E
Q
I
V
I
N
N
N
G
S
T
F
LPTGQNYT
K
T
D
F
E
H
D
V
M
N
V
V
W
S
Y
A
A
M
T
V
G
M
W
A
A
G
Q
I
T
V
T
C
Y
L
Y
V
A
E
Q
M
N
N
R
L
R
R
E
F
V
K
S
I
L
R
QE
I
S
W
F
D
T
N
HSGT
L
A
T
K
L
F
D
N
L
E
R
V
K
E
G
T
GD
K
I
G
M
A
F
Q
Y
L
S
Q
F
I
T
G
F
I
V
A
F
T
H
S
W
Q
L
T
L
V
M
L
A
V
T
P
I
Q
A
L
C
G
F
A
I
A
K
S
M
S
T
F
A
I
R
E
T
L
R
Y
A
K
A
G
K
V
V
E
E
T
I
S
S
I
R
T
V
V
S
L
NG
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
K
K
A
G
V
L
K
G
L
F
L
G
I
S
F
G
A
M
Q
A
S
N
F
I
S
F
A
L
A
F
Y
I
G
V
G
W
V
H
D
GSLN
F
G
D
M
L
T
T
F
S
S
V
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
G
T
A
Q
G
A
A
S
G
I
Y
E
V
LDRKPVIDSS
S
K
A
G
R
KDMKI
K
G
D
I
T
V
E
N
V
H
F
-
T
Y
P
S
--
R
P
DVP
I
L
-
R
G
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
R
Y
Y
D
V
L
K
G
K
I
T
I
D
-------
G
V
D
V
-----
R
-------
D
--
I
N
L
E
F
L
R
K
N
V
A
V
----
V
-----
S
Q
E
P
A
L
F
N
-
C
-
T
I
E
E
N
I
S
L
G
----
K
EG
I
T
R
E
E
M
V
A
A
C
K
M
A
N
A
E
K
F
I
K
T
L
P
N
---
G
Y
N
T
-----------
L
V
G
D
R
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
S
E
G
I
V
Q
Q
A
L
D
K
A
A
K
--
G
R
T
T
I
I
I
A
H
R
L
S
T
I
R
N
-
A
D
L
I
I
S
C
----
K
--------------------
N
G
Q
V
V
E
V
G
D
H
R
A
L
M
A
Q
QG
L
Y
Y
D
L
V
T
A
Q
T
F
T
D
A
V
D
S
A
A
E
GER
I
G
K
D
A
L
S
R
L
K
Q
E
L
E
ENNAQKTN
L
F
E
I
L
Y
H
A
RPH
A
L
S
L
F
I
G
M
S
T
A
T
I
G
G
F
I
Y
P
T
Y
S
V
F
F
T
S
F
M
N
V
F
AGNPADFL
S
Q
G
H
F
W
A
L
M
F
L
V
L
A
A
A
Q
G
I
C
S
F
L
M
T
F
F
M
G
I
A
S
E
S
L
T
R
D
L
R
N
K
L
F
R
N
V
L
S
QHIGFFDSPQNA
S
G
K
I
S
T
R
L
A
T
D
V
P
N
L
R
T
A
I
D
F
R
F
S
T
V
I
T
T
L
V
S
M
V
A
G
I
G
L
A
F
F
Y
G
W
Q
M
A
L
L
I
I
A
I
L
P
I
V
A
F
G
Q
Y
L
R
G
RRFTGKNVKSA
S
E
F
A
D
S
G
K
I
A
I
E
A
I
E
N
V
R
T
V
Q
A
L
AR
E
D
T
F
Y
E
N
F
C
E
K
L
D
I
P
H
K
E
A
I
K
E
A
F
I
Q
G
L
S
Y
G
C
A
S
S
V
L
Y
L
L
N
T
C
A
Y
R
M
G
L
A
L
I
I
TDPPTMQ
P
M
R
V
L
R
V
M
Y
A
I
T
I
S
T
S
TLGFAT
S
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
F
G
M
L
R
KISKIDSLSLAGEKKKLYGK
V
I
F
K
N
V
R
F
A
Y
PERPEIEILK
G
L
S
F
S
V
E
PG
Q
T
L
A
L
V
G
P
S
GCGKST
V
V
A
L
L
E
RFYDTL
G
G
E
I
F
I
DGSEIKTLN
P
E
H
T
R
S
Q
I
A
I
V
S
Q
E
P
T
L
F
DCS
I
A
E
N
I
I
YGLDPSSVT
M
A
Q
V
E
E
A
A
R
L
A
NI
H
N
F
I
A
E
LPEGFETRVGDRGTQLS
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
NPK
I
L
L
L
D
EATSALDT
E
S
E
K
V
V
Q
E
A
L
D
R
A
R
EG
R
T
C
I
V
I
A
HRLNTVMNAD
C
I
A
V
V
S
NGTII
E
K
G
T
H
T
Q
L
M
S
E
K
3
PsiBlast_PDB
61.89
33%
19
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[10-213]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
K
-
S
F
Q
N
--
T
P
---
V
L
-
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
GKTIFSK
N
T
N
L
-----
P
-------
V
R
E
R
R
L
G
Y
L
V
Q
E
-------------
G
V
L
---
F
P
-
H
L
T
V
Y
R
N
I
A
Y
G
----
L
--
G
N
G
K
G
R
----
T
-
A
Q
E
R
Q
R
I
E
A
M
L
E
L
-
T
G
I
S
E
-----------
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
61.50
23%
-44
- C1 -
-
2AWN
1
MALK_ECOLI
B:
[2-216]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
V
Q
L
Q
N
V
T
K
-
A
W
G
E
--
V
V
---
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
-------
E
K
R
M
-----
N
DTP----
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
-----
L
-----
Y
-----
P
H
-
L
-
S
V
A
E
N
M
S
F
G
----
L
--
K
L
A
----
G
A
K
K
-
E
V
I
N
Q
R
V
N
Q
V
A
E
V
-
L
Q
L
A
H
-----------
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
----
D
A
G
R
-----
V
A
Q
V
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
60.82
29%
-
- C1 -
-
4RFS
-
ECFA1_LACBA
B:
[3-223]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
I
I
S
V
D
H
L
T
Y
-
Q
Y
D
E
NQ
A
P
---
A
L
-
T
D
V
S
F
T
V
H
A
G
E
W
L
A
I
V
G
H
N
G
S
G
K
S
T
L
A
K
S
L
D
G
L
L
P
F
T
Q
G
S
V
T
V
G
-------
G
I
T
L
-----
T
PET
V
W
--
Q
V
R
E
Q
I
G
M
I
F
Q
N
P
D
N
----
Q
-----
F
-----
V
G
-
A
-
T
V
E
D
D
V
A
F
G
----
L
--
E
N
R
Q
----
I
S
R
-
D
E
M
V
P
R
V
Q
A
A
L
A
Q
-
V
G
M
T
S
-----------
F
A
Q
R
E
P
S
S
L
S
G
G
Q
K
Q
R
V
A
L
A
G
I
V
A
I
A
P
K
I
L
I
L
D
E
A
T
S
M
L
D
P
Q
G
R
I
E
M
L
A
I
V
R
Q
L
R
Q
Q
Q
N
L
T
V
I
S
I
T
H
D
I
D
E
A
A
-
S
A
D
R
V
L
V
I
----
D
D
G
R
-----
L
V
D
E
A
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
60.44
29%
-
* C1 *
-
4HUQ
-
ECFA1_LACBA
B:
[3-223]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
I
I
S
V
D
H
L
T
Y
-
Q
Y
D
E
NQ
A
P
---
A
L
-
T
D
V
S
F
T
V
H
A
G
E
W
L
A
I
V
G
H
N
G
S
G
K
S
T
L
A
K
S
L
D
G
L
L
P
F
T
Q
G
S
V
T
V
G
-------
G
I
T
L
-----
T
PET
V
W
--
Q
V
R
E
Q
I
G
M
I
F
Q
N
P
D
N
----
Q
-----
F
-----
V
G
-
A
-
T
V
E
D
D
V
A
F
G
----
L
--
E
N
R
Q
----
I
S
R
-
D
E
M
V
P
R
V
Q
A
A
L
A
Q
-
V
G
M
T
S
-----------
F
A
Q
R
E
P
S
S
L
S
G
G
Q
K
Q
R
V
A
L
A
G
I
V
A
I
A
P
K
I
L
I
L
D
E
A
T
S
M
L
D
P
Q
G
R
I
E
M
L
A
I
V
R
Q
L
R
Q
Q
Q
N
L
T
V
I
S
I
T
H
D
I
D
E
A
A
-
S
A
D
R
V
L
V
I
----
D
D
G
R
-----
L
V
D
E
A
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
59.97
23%
-41
- C1 -
-
5MKK
-
?
B:
[337-555]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
R
F
E
G
V
G
L
-
K
R
D
G
--
R
W
---
L
L
-
R
G
L
T
L
T
I
P
E
G
M
T
L
G
I
T
G
R
T
G
S
G
K
S
L
L
A
A
L
V
P
R
L
L
D
P
S
E
G
R
V
Y
V
G
-------
G
H
E
A
-----
R
RIP
L
A
--
V
L
R
K
A
V
G
V
A
P
Q
E
P
F
L
----------------
F
S
-
E
-
T
I
L
E
N
I
A
F
G
----
L
--
D
E
V
-----------
D
R
E
R
V
E
W
A
A
R
L
-
A
G
I
H
E
E
I
L
A
FPKGYET
V
L
G
E
R
G
I
T
L
S
G
G
Q
R
Q
R
V
A
L
A
R
A
L
A
K
R
P
K
I
L
I
L
D
D
A
L
S
A
V
D
A
E
T
E
A
R
I
L
Q
G
L
K
T
V
L
--
G
K
Q
T
T
L
L
I
S
H
R
T
A
A
L
R
-
H
A
D
W
I
I
V
L
----
D
G
G
R
-----
I
V
E
E
G
T
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
59.40
23%
-49
- C1 -
-
3RLF
2
MALK_ECOLI
A:
[2-216]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
V
Q
L
Q
N
V
T
K
-
A
W
G
E
--
V
V
---
V
S
-
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
-------
E
K
R
M
-----
N
DTP----
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
-----
L
-----
Y
-----
P
H
-
L
-
S
V
A
E
N
M
S
F
G
----
L
--
K
L
A
----
G
A
K
K
-
E
V
I
N
Q
R
V
N
Q
V
A
E
V
-
L
Q
L
A
H
-----------
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
----
D
A
G
R
-----
V
A
Q
V
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.62
27%
6
- C1 -
-
1VPL
-
?
A:
[14-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
V
V
V
K
D
L
R
K
-
R
I
G
K
--
K
E
---
I
L
-
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
-------
G
K
N
V
VEE
P
H
E
-------
V
R
K
L
-
I
S
Y
L
P
E
E
A
G
A
----
Y
-----
R
N
M
---
Q
G
-
I
-
E
Y
L
R
F
V
A
-------------
G
F
Y
A
S
S
S
-
S
E
I
E
E
M
V
E
R
A
T
E
I
-
A
G
L
G
E
-----------
K
I
K
D
R
V
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
-
A
S
Q
E
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
-
I
A
L
----
I
-
H
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------