@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKA9: (2017-10-25 )
MPIDTQLTTLFCLIDDFCTDITQNVEQYMLTYGQTKRLRQSKIHASEVITLLLWFHLTGSRNFKAFYLYWAKPFLCSYFTNLPSYSRFIELKAKYAMYFVALIESLKVHSAGIAFIDSTKLAVCHNKRIHQHRVFADSASRGKTSVDWFYGFKIHLICDHIGRLVSYCITTGNVDDRKVLPDLIEHSKLKGKLFGDRSYVGKNWKSRLAEVGVQLITRVKRNMKPQVLAPFDHAVLRKRGIIEAPFKLMKSQFDLEHSRHRSKMGLLTTIFAALTLYALVLVNGYKSGIQQILKPIDLNSA
Atome Classification :
(20 SA)
---------------------------------------------...-----......10-------------------.....--...20.---------------...-------....30---.......-.40........50.......-.60.---.......-----70...-------.....80........90........100.......110--....--.--...120.......130.......140.......150.......160.......170......---------------.180.......190.......200.......210-----........220.......230---.........----240.......250...---....260....-...270.......280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------MPI-----DTQ
L
T
T
L
F
-------------------
C
L
I
D
D
--
F
C
T
D
I
T
---------------
Q
N
V
-------
E
Q
Y
M
L
T
---YG
Q
T
K
R
L
-
R
Q
SKI
H
A
S
E
V
I
T
L
L
L
W
F
HLT-GSR
N
---
F
K
A
F
Y
L
Y
-----WA
K
P
F
-------
L
C
S
Y
F
TNLP
S
Y
S
R
F
I
E
L
K
A
K
Y
A
M
Y
F
V
A
L
I
E
S
L
KVHSA---
G
I
A
F
--I--DS
T
K
L
A
V
C
HNKRI
H
Q
H
R
VFADSASRGK
T
S
V
D
W
F
Y
G
F
K
I
H
L
I
C
D
H
I
G
R
L
V
S
Y
C
ITTGNVD
D
R
K
---------------
V
L
P
D
L
I
E
H
S
KLK
G
K
LFGDRSYVG
K
N
W
K
S
R
L
A
E
V
------
G
V
Q
L
I
T
R
V
K
RNMKP
Q
V
LAP-----F
D
H
A
V
L
R
KR----GI
I
E
A
P
F
K
L
M
K
S
Q
FD
L
---
E
H
S
R
H
R
S
KM
G
L
-
L
T
T
I
F
A
A
L
T
L
Y
A
L
V
L
V
N
G
Y
K
S
G
I
Q
Q
I
L
K
PIDLNSA
34
Fugue
71.46
19%
-
- C1 -
-
4N74
-
?
A:
[264-577]
---------------------TQ
N
T
I
E
T
G
V
G
Y
S
TDV
G
P
R
V
K
A
T
W
K
K
P
W
VNSYG
H
S
L
T
T
S
T
S
-------------------
I
S
A
P
E
--
Q
T
L
D
F
S
---------------
Y
K
M
P
L
LKNPL
E
Q
Y
Y
L
V
---
Q
G
G
F
K
R
T
-
D
L
N
D
T
E
S
D
S
T
T
L
V
A
S
R
Y
W
D
L
-
S
S
G
W
---
Q
R
A
I
N
L
R
-----
W
S
V
D
H
-------
F
T
Q
G
-----------
E
I
T
N
T
T
M
L
F
Y
P
G
V
V
I
S
R
T
R
S
R
G
---
G
L
M
P
--
T
W
G
D
S
Q
R
Y
S
I
D
Y
S
N
T
A
W
G
S
D
V
D
F
S
V
F
Q
A
Q
N
V
W
I
R
T
L
Y
D
R
H
R
F
V
T
R
G
T
L
G
W
I
E
T
-------
G
D
F
D
K
---------------
V
P
P
D
L
R
F
F
A
G
------
G
D
R
S
I
R
G
Y
K
Y
K
S
I
A
P
K
Y
ANG
D
L
K
G
A
S
K
L
I
T
G
S
L
E
Y
Q
Y
N
V
T
G
K
-----
W
W
G
A
V
F
V
D
S
----
G
--
E
A
V
S
D
I
R
R
S
D
F
K
T
G
T
G
V
G
V
R
W
E
S
P
V
G
P
-
I
K
L
D
F
A
V
P
V
A
------
D
K
D
E
H
G
L
Q
F
Y
I
G
L
G
P
E
L
--
30
Fugue
52.11
15%
-16
- C4 -
-
5HC3
-
?
A:
[22-365]
MTNKIAEDPRID
P
R
I
K
A
I
FSGMDL
G
G
G
G
D
V
ES
R
E
A
M
L
E
A
A
S
S
E
E
A
T
A
V
-----
R
D
G
L
R
V
F
L
-------------------
D
A
C
D
N
EE
I
A
P
S
A
G
---------------
L
K
I
-------
E
D
Y
E
F
T
S
E
P
D
G
N
I
A
K
I
-
Q
Y
I
R
P
D
S
T
D
K
L
P
C
V
Y
Y
I
H
G
G
-
G
M
Q
S
LSC
Y
Y
G
N
Y
R
A
-----
W
G
K
I
I
A
S
N
G
V
A
V
A
M
V
E
F
R
N
A
L
V
P
S
A
L
P
E
V
-
A
P
Y
P
A
G
L
N
D
C
V
S
G
V
K
W
V
A
A
---
H
A
D
E
LG
I
--
D
A
S
R
I
I
I
A
G
E
S
G
G
G
N
L
T
L
A
A
G
L
R
L
K
Q
E
G
S
Q
D
L
I
Q
G
--
L
Y
A
L
C
P
Y
I
A
G
S
W
P
S
E
D
S
P
S
S
T
E
N
N
G
---------------
I
L
L
D
L
--
H
N
N
Q
G
A
M
G
Y
G
I
E
A
Y
E
M
R
D
P
L
A
W
P
G
F
A
------
T
E
E
D
V
S
----
G
L
V
P
T
F
I
S
V
-----
N
E
C
D
P
L
R
D
E
----
G
I
-
N
F
Y
R
L
L
L
R
A
G
V
S
------
A
K
C
R
Q
V
M
G
----
T
I
H
G
-
T
E
I
F
P
I
A
C
P
D
V
S
R
D
T
A
A
S
I
A
N
F
C
K
G
G
--
37
Fugue
49.34
20%
-16
- C2 -
-
4USR
2
?
A:
[1-357]
---------------------GPAMPPILD
V
I
V
I
G
GG
Q
A
A
L
T
T
A
Y
F
L
R
-----
R
T
S
L
S
Y
L
L
L
D
EQPGPGGAWLHAWDSLR
L
F
S
P
A
--
A
W
S
S
I
A
GWPMPSPTEPGNPT
R
N
D
V
-------
I
D
Y
L
R
R
---
Y
E
D
R
Y
Q
F
P
I
Q
R
P
V
R
V
D
T
V
T
R
L
D
D
L
W
R
V
Q
A
G
D
Q
Q
---
W
L
A
R
A
V
I
S
ATGT
W
S
K
P
F
-------
I
-------
P
P
Y
E
G
------------
R
E
L
F
Q
G
A
Q
I
H
S
A
HYR
T
P
A
P
--
F
--
A
G
K
R
V
M
V
V
G
G
G
N
-
S
G
A
Q
V
L
A
E
L
S
S
V
--
S
E
T
L
W
I
T
Q
E
P
P
A
F
L
P
D
E
V
D
G
R
V
L
F
E
R
A
T
A
R
W
K
A
Q
Q
EGRSIDEPAGGFGDI
V
M
V
P
P
V
R
E
A
R
E
R
G
V
L
V
A
E
R
P
F
------
A
R
F
T
E
T
------
G
V
E
W
A
D
G
R
R
E
N
L
D
A
V
I
W
C
S
GFRPA
L
D
H
L
--
R
E
L
----
G
V
V
E
A
D
G
K
V
Q
V
E
D
T
R
V
---
V
K
Q
P
N
L
W
L
V
G
Y
G
D
W
T
G
M
A
S
A
T
L
I
G
V
T
R
T
--
A
R
S
T
A
D
Q
V
V
Q
A
L
T
A
T
P
-
33
Fugue
41.76
16%
-112
- C4 -
-
5JRC
-
?
A:
[34-219]
------------------------------------------------------------------------------------
S
--
M
L
P
N
L
D
---------------
N
L
K
-------
E
E
Y
Q
K
L
---
E
E
K
K
Q
E
I
-
V
D
R
S
I
R
M
S
K
L
S
K
S
L
I
Y
S
M
I
R
-
E
D
Y
K
---
S
A
D
K
Y
K
E
-----
E
L
T
N
L
-------
A
K
T
Q
I
E
E
L
K
K
Y
----------
P
M
F
Y
S
N
G
F
I
G
L
Q
E
Y
V
E
---
A
L
A
L
--
Y
--
Y
Y
I
K
E
----
N
R
I
P
S
K
E
E
L
G
V
D
---------
T
W
V
Y
L
F
G
I
G
D
I
A
G
E
I
L
R
K
S
S
E
E
L
I
K
G
N
I
E
Y
A
K
---------------
K
A
K
Q
D
L
E
S
L
Y
L
D
L
L
Y
I
E
L
K
N
F
D
L
R
R
K
L
D
Y
V
S
N
I
------
I
N
K
L
I
E
F
I
I
W
K
S
K
------------------------------------------------------------------------------------------
14
PsiBlast_PDB
41.31
25%
-129
- C5 -
-
1AZS
1
GNAS2_BOVIN
C:
[128-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
H
M
--------------------------------------------------
9
PsiBlast_PDB
41.16
25%
-129
- C5 -
-
1U0H
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
15
PsiBlast_PDB
40.97
25%
-134
- C5 -
-
1AZT
1
GNAS2_BOVIN
A:
[128-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
H
M
--------------------------------------------------
6
PsiBlast_PDB
40.83
25%
-141
- C5 -
-
1CJV
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
12
PsiBlast_PDB
40.80
25%
-125
- C5 -
-
3G82
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
13
PsiBlast_PDB
40.45
25%
-106
- C5 -
-
3MAA
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
VLTS
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
4
PsiBlast_PDB
40.39
25%
-138
- C5 -
-
1CJT
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
7
PsiBlast_PDB
40.37
25%
-121
- C5 -
-
1TL7
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
8
PsiBlast_PDB
40.36
25%
-137
- C5 -
-
1CS4
1
GNAS2_BOVIN
C:
[128-220]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
2
PsiBlast_PDB
39.78
25%
-135
- C5 -
-
1CUL
1
GNAS2_BOVIN
C:
[114-205]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
3
PsiBlast_PDB
39.53
25%
-133
- C5 -
-
1CJK
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
1
PsiBlast_PDB
39.33
25%
-106
- C5 -
-
3SN6
-
GNAS2_BOVIN
A:
[114-212]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
VS--
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
18
PsiBlast_PDB
39.18
25%
-124
- C5 -
-
3C16
1
GNAS2_BOVIN
C:
[128-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
H
M
--------------------------------------------------
10
PsiBlast_PDB
38.81
25%
-126
- C5 -
-
2GVD
1
GNAS2_BOVIN
C:
[128-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
----------------------------------------------------
17
PsiBlast_PDB
38.61
25%
-121
- C5 -
-
3C15
1
GNAS2_BOVIN
C:
[128-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
H
M
--------------------------------------------------
16
PsiBlast_PDB
38.12
25%
-128
- C5 -
-
3C14
1
GNAS2_BOVIN
C:
[128-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Y
I
L
S
V
M
N
V
P
D
F
D
---------------
F
P
P
E
F
Y
E
H
A
K
A
L
W
E
D
E
G
V
R
A
C
Y
E
R
S
N
E
Y
Q
L
I
D
C
------
A
Q
Y
F
L
D
K
I
D
V
-
I
K
Q
D
D
Y
V
P
-----
S
D
Q
D
L
L
R
C
R
V
L
T
S
G
I
F
E
T
K
F
Q
V
D
K
V
N
F
H
M
--------------------------------------------------