@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKE1: (2017-10-26 )
MFLSQIDEMLIGDLDLQFVMPWEFEDLNPEAFREFNRELYAHRFDLDYESYSVDNDIDLHLSNYYSSCETNKLIPSNCFFKLVEYMLVVLESRSFTSLFSNCVEFYNTKYSNEYLTFFLNLFSTSKSEVARDNLRMYITEIFDDKRYWANNELFDDSLLFEENLQQLQIIRVM
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------........---.10-..--....-------..20--..-...-...30........40-.-----.....-..50..-.-.....60...-.....70.--...-...-.80---........90..-----.-.....100.......110......--.120...---.-...------130........140..-..---..-.150---..-.......160.....--..170.-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
F
L
S
Q
I
D
E
---
M
L
I-GD--L
D
L
Q
-------
F
VMP--WE-FED-L
N
P
E
A
F
R
E
F
N
R
E
L
Y
A
-
H
-----RFDLD-YESYSV-D-N
D
I
D
L
H
L
S
N
Y
-YSSCETNK--LI
P
-
S
N
C
-
F
F
K
---
L
V
E
Y
M
L
V
V
LESR-----
S
-
F
T
S
L
F
S
N
C
V
E
F
YNTKYS
N
E
Y
L
T
F
F
--
L
N
L
F
ST
S
---
K
-
S
E
V
------
A
-
R
D
N
L
R
M
Y
I
T
E
IFDD-KR---YW-AN-----NE-LFD
D
S
L
L
F
E
E
N
L
Q
Q
L
--
Q
I
I
RVM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.38
25%
0
- C- -
-
4XGC
-
ORC5_DROME
E:
[163-316]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
K
F
-
Y
N
K
T
G
L
-
S
-
E
I
V
C
L
H
L
A
Q
Y
--
N
K
A
E
T
Q
R
--
I
L
G
-
S
D
---
F
Q
---
Q
V
R
N
Q
L
L
E
Q
----------
K
K
R
L
-
E
I
C
Q
E
A
V
T
E
D
F
Y
N
N
Y
L
N
L
F
--
L
S
V
F
Y
K
A
---
C
-
R
D
V
P
E
L
Q
L
T
A
-
R
K
C
L
S
T
Y
L
E
P
V
L
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
65.19
17%
-11
* C1 *
-
4XDN
-
SCC4_YEAST
A:
[24-640]
G
D
K
L
S
I
S
Q
V
Y
H
L
A
Q
E
Y
R
D
H
A
Y
S
I
A
NKIGS
E
E
G
L
K
Q
Y
Y
G
L
M
N
M
S
I
Q
M
F
Q
L
L
K
T
KCTLS
V
L
E
D
S
K
V
T
F
E
M
V
E
L
L
I
Q
ETYN
F
D
L
A
E
L
Y
I
S
S
L
K
E
R
L
Q
T
H
QSDTDL
V
E
E
I
M
R
C
E
F
L
L
L
H
D
L
P
L
M
R
DS
K
F
H
Y
K
I
A
L
R
N
C
N
E
L
V
Q
Y
M
V
N
LQD
E
L
Y
Q
N
W
A
S
V
F
Q
Y
V
G
V
M
L
C
I
K
L
KQ
H
R
R
V
K
T
S
F
H
G
L
L
S
Q
CREKS
Q
W
K
W
F
L
N
L
C
Y
V
N
Y
---
L
L
N
-
E
R
--
F
P
I
P
-------
E
D
A
L
--
Q
E
-
L
R
S
-
T
E
---
L
H
T
V
G
P
E
L
Y
A
-
W
-----
K
L
A
L
E
-
M
V
I
Q
L
C
K
D
-
G
N
I
T
D
H
L
N
E
F
-
K
N
F
F
D
T
N
K
Q
S
L
V
T
-
N
E
G
-
K
G
C
---
V
I
K
I
M
P
R
I
A
L
K
V
-----
E
-
L
P
M
I
F
-
H
Y
K
E
L
K
N
I
L
L
L
L
Q
S
V
S
Y
I
--
V
N
C
Y
D
-
E
---
K
-
G
N
F
------
S
-
R
K
F
L
P
K
V
Y
S
T
T
Q
K
L
-
I
K
---
N
I
-
A
A
G
GVS
M
N
E
-
L
D
S
R
I
Q
T
Y
K
S
I
L
E
F
C
--
E
F
Y
K
V
W
E
Q
T
L
L
K
GAVVLGPSPG
Y
V
R
L
L
Q
A
M
K
V
Q
F
E
GGGA
V
E
E
Y
T
R
L
A
Q
SGGTS
S
E
V
K
M
I
S
L
L
N
C
Y
T
V
Q
A
A
R
V
S
R
CSGDK
Q
G
E
L
V
E
Q
C
N
K
V
W
L
Q
V
E
K
L
L
Q
E
T
DLQFN
P
I
W
E
C
T
V
T
I
L
W
L
F
S
H
F
EPFSWNPLPCS
D
K
Q
R
A
E
Y
V
S
K
L
R
E
F
Y
S
S
N
KFVNRFKLKKA
L
L
L
Q
I
L
V
N
Y
L
G
G
R
M
LEHD
L
G
E
I
Y
A
I
S
A
K
C
F
D
M
C
R
QQGGM
R
K
V
Q
Y
V
I
G
I
W
H
L
M
N
C
T
V
A
MR
G
K
D
V
A
L
T
N
A
K
L
E
A
L
V
K
Q
I
T
S
17
Fugue
64.07
21%
9
- C2 -
-
2G3V
-
CAGS_HELPY
A:
[22-182]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
I
-
E
S
--
L
Q
----------------
E
-
N
E
L
-
L
N
T
D
E
K
K
K
I
I
D
Q
I
K
T
M
H
-----
D
F
F
K
Q
M
H
T
N
----
K
-
G
A
L
D
K
V
L
R
N
Y
M
K
D
---
Y
R
A
--
V
I
K
-
S
I
G
-
V
D
K
---
F
K
K
V
Y
R
L
L
E
S
E
T
M
----
E
-
L
L
H
A
I
A
E
N
P
N
F
L
F
S
K
F
D
R
S
I
L
G
I
F
--
L
P
F
F
S
K
P
I
M
F
K
M
S
I
R
------
E
M
D
S
Q
I
E
L
Y
G
T
K
L
P
L
L
-
K
L
---
F
V
M
T
D
-----
E
E
M
N
F
Y
A
N
L
K
T
I
E
Q
Y
N
D
Y
--
V
R
D
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
57.07
18%
21
- C1 -
-
1Y9L
1
MXIM_SHIFL
A:
[6-115]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
E
W
H
--
I
V
P
V
S
K
D
-
Y
F
S
---
I
P
N
D
L
L
W
S
F
N
T
T
-----
N
K
S
I
N
V
Y
S
K
C
I
S
G
K
-
A
V
Y
S
F
N
A
G
K
F
M
--
G
N
F
N
V
K
E
---
V
-
D
G
C
------
F
-
M
D
A
Q
K
I
A
I
D
K
L
F
S
M
-
L
K
D
G
V
V
L
-
K
G
-----
N
K
-
I
N
D
T
I
L
I
E
K
D
G
E
V
K
L
--
K
L
I
R
G
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
54.06
14%
-124
- C4 -
-
5ICA
-
?
A:
[1-163]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
Q
T
V
E
---
T
L
M
-
A
G
--
E
R
I
A
-------
E
A
L
E
--
L
G
-
M
T
D
-
L
--
N
T
I
R
E
W
E
E
A
R
Q
I
-
N
---------
P
-
N
I
A
P
P
Q
-
R
-
N
P
I
F
V
A
L
G
N
I
-
P
A
E
T
Y
V
L
N
--
T
L
Q
-
K
I
K
-
P
A
S
---
L
H
D
A
L
L
V
-
L
P
F
S
-----
T
-
I
P
S
L
L
T
F
L
N
L
F
A
Q
R
E
L
N
V
P
L
T
C
R
I
--
L
F
F
V
L
K
T
---
H
-
H
K
Q
------
I
-
V
A
S
--
R
T
M
R
A
T
L
E
K
-
V
R
---
A
N
-
L
R
-----
A
A
-
L
R
R
Q
K
D
E
M
G
F
N
I
A
A
L
--
K
V
V
S
M
Q
L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
53.46
9%
9
* C4 *
-
2Q3F
1
RRAGD_HUMAN
A:
[3-181]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
P
R
---
I
L
L
M
G
L
R
R
S
G
K
S
-------
S
I
Q
K
--
V
V
-
F
H
K
M
S
P
N
E
T
L
F
------
L
E
-
S
-----
T
N
K
I
C
-
R
E
D
V
S
N
-
S
-
S
F
V
N
F
Q
I
W
D
F
-
P
G
Q
I
D
F
F
D
--
P
T
F
-
D
Y
E
M
I
F
R
---
G
T
G
A
L
I
F
V
I
D
S
Q
DDY
M
E
A
-
L
A
R
L
H
L
T
V
T
R
A
Y
K
V
N
T
D
I
N
F
E
V
F
I
HK
V
D
G
L
S
D
D
---
H
-
K
I
E
------
T
-
Q
R
D
I
H
Q
R
A
N
D
D
L
A
D
-
A
G
---
L
E
-
K
I
-----
H
L
-
S
F
Y
L
T
S
I
Y
D
H
S
I
F
E
A
F
S
K
V
V
Q
K
L
IP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
52.88
26%
22
- C5 -
-
3I44
-
?
A:
[357-442]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
Q
S
G
I
D
E
GAT
L
V
T
-
G
G
--
T
G
L
P
MGMERGY
Y
V
R
P
--
T
V
-
F
A
D
-
V
K
P
H
-
M
R
I
F
R
E
E
I
F
G
-
P
V
L
S
L
L
P
F
N
T
E
-
D
E
A
V
T
L
-
A
-
N
D
T
E
Y
G
L
T
N
Y
-
I
Q
S
Q
D
R
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
50.48
18%
9
- C2 -
-
5HMO
-
MYO10_BOVIN
A:
[1-131]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
---
Q
L
R
-
G
Q
--
I
A
R
R
-------
V
Y
R
Q
--
L
L
-
A
E
K
-
R
A
E
E
E
K
R
K
R
E
E
E
E
K
R
-
K
-----
R
E
E
E
E
-
R
E
R
E
R
E
-
R
-
R
E
A
E
L
R
A
Q
Q
E
-
E
A
A
R
K
Q
R
E
--
L
-------------------------------------------
E
A
L
Q
Q
E
S
Q
R
A
A
E
L
--
S
R
E
L
E
K
Q
---
K
-
E
N
K
------
Q
-
V
E
E
I
L
R
L
E
K
E
I
E
D
L
-
Q
R
---
M
K
-
E
R
-----
Q
E
-
L
S
----
L
T
E
A
S
L
Q
K
L
--
Q
Q
L
R
D
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
48.53
32%
-264
- C5 -
-
4JD9
-
?
E:
[90-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
I
D
Y
-
Y
R
C
V
L
T
S
K
--
L
I
G
-
P
Q
R
-
F
D
K
---
A
I
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
46.83
22%
-119
* C2 *
-
2Q2K
2
?
A:
[23-67]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
T
K
H
L
L
K
I
K
K
E
D
Y
P
Q
I
F
D
F
L
--
E
N
V
P
R
G
T
---
K
-
T
A
H
------
I
-
R
E
A
L
R
R
Y
I
E
E
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
44.15
17%
-23
- C2 -
-
2KL8
-
?
A:
[1-85]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
M
D
--
I
R
-
F
R
G
-
D
D
L
E
A
F
E
K
A
L
K
E
M
I
R
-
Q
A
----
R
K
F
A
G
-
T
V
T
Y
T
L
-
D
G
N
D
L
E
I
R
I
T
G
V
-
P
E
Q
V
R
K
E
L
--
A
K
E
-
A
E
R
-
L
A
K
E
F
N
I
T
V
T
Y
T
I
R
L
E
H
H
-----
H
-
H
H
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
40.16
33%
-77
- C5 -
-
2HH8
-
YDFO_ECOLI
A:
[93-133]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
E
Y
---
R
-
R
N
L
------
A
-
K
A
G
V
F
R
W
V
T
N
I
H
E
Q
-
K
R
---
Y
Y
-
Y
T
---------
F
D
N
S
L
L
F
T
E
S
I
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
37.49
34%
-122
- C5 -
-
2N7D
-
DDI2_HUMAN
A:
[26-63]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
C
-
V
-----
R
R
D
L
S
-
E
V
T
F
S
L
-
Q
-
V
D
A
D
F
E
L
H
N
F
-
R
A
L
C
E
L
E
S
--
G
I
P
-
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
37.42
27%
-46
* C3 *
-
1FQJ
-
C:
[9-39]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
G
---
M
E
G
-
L
G
--
T
D
I
T
-------
V
I
C
P
--
W
E
A
F
N
H
-
L
E
L
H
E
L
A
Q
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
29.12
38%
-14
- C5 -
-
2JQ3
-
APOC3_HUMAN
A:
[27-56]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
S
V
Q
---
E
-
S
Q
V
------
A
-
Q
Q
A
-
R
G
W
V
T
D
G
F
S
S
L
K
D
---
Y
W
-
S
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
26.50
38%
52
- C3 -
-
2KYJ
-
A:
[1-16]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
P
L
S
K
E
-
Y
E
S
C
V
R
P
R
--
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
26.48
21%
135
- C5 -
-
4AKR
-
CAPZA_DICDI
C:
[29-59]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
R
-------
A
L
L
P
SE
S
L
-
L
N
A
-
S
A
G
S
T
F
R
E
Y
N
T
S
Q
M
V
-
S
-----
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
25.07
29%
213
* C5 *
-
2K6L
-
?
B:
[31-47]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
---
L
-
S
R
F
------
I
-
E
D
A
V
R
A
Y
L
F
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
21.94
22%
31
- C- -
-
2HH6
-
?
A:
[4-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
K
M
I
G
S
L
N
D
-
K
R
---
E
W
-
K
A
-----
M
E
-
A
R
A
K
A
L
P
K
E
Y
H
-
H
A
Y
--
K
A
I
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
21.47
27%
-3
- C5 -
-
3U21
-
B:
[7-24]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
S
S
S
-
F
F
S
---
L
L
L
E
I
L
L
L
E
S
Q
A
-----
S
-
L
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------