@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKF2: (2017-10-26 )
MKNIRIGSYHWMQTTNGQLSFKEKIKLIQKIMVPSILSSIKINYYRFQTGNDFDIGQIVIPDTQMIKIALEELESKASISIYNHSWRTYFWGAALGHLQNQQFDPESLLLASLFHDIGLTEQHMHSKGCQCFTYESAKQFEQKAKEYNFDDKKSEVIKDAICLHMNGYIEDSDPPEVVLLQQGASCDVISDNQYKLPLSFRNKILEKYPRNQFNKEFIKLINLERKNVPNSRTGLLYDLGLPLMIKSNLYNENLI
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20.....-------...30........40----.........50....-------------...-------------------------.60........---70.....---------------.----..80....--.-------------...90------.......--..100......----------.110...---------...-.----------120----..------.---.----------.---.-----------.---------130------------------.....----..------140..-...--..150-.......160------...-.....170----------------------........---.180.......---190..-------.-----.---...-200-------....--.------...210-.-----........220.....-..230..-.....240.....--..250...-------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKN
I
R
IG
S
Y
H
W
M
QTTNG
Q
L
S
F
K
E
K
I
K
-------
L
I
Q
K
I
M
V
P
S
I
L
S
S
I
-----
K
I
N
Y
Y
R
FQTGNDFD
I
-------------
G
Q
I
-------------------------VIPD
T
Q
M
I
K
I
A
---
L
E
E
L
ESK---------------A----
S
I
S
I
Y
NH
S
--
W
-------------
R
T
Y
F
-------
W
G
A
A
L
G
H
--LQNQQF
D
P
E
S
L
----------
L
L
A
S
L
F
H
---------DIG-L----------
T
E
Q
----
H
M
------H---S----------K---G-----------
C
---------
Q
C
F
------------------
T
Y
E
S
A
----
K
Q
------
F
E
Q
K
A
-
K
EY--NFD
D
K
-
K
S
E
V
I
K
D
A
I
-------
C
L
H-MNGYIE------------------------DSDPP
E
V
V
---
L
L
QQGASCDVI---SDN
Q
Y
-------
K
-----L---
P
L
S
-
F
R
--------
N
K
I
L
--
E
------KYPR---N-----QF
N
K
E
F
I
K
L
I
N
L
ERKN-VPNSRT
G
-
L
L
Y
DLGL
P
L
M
I
KS--NLYNENLI-------------------
6
HHSearch
56.09
16%
-97
- C6 -
-
3B57
-
?
A:
[2-131]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
E
E
I
I
L
S
A
---
K
N
W
M
H
S
H
---------------
F
------
H
D
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H
I
--
K
-------------
R
V
W
K
-------
L
S
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E
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--
K
E
G
--
G
D
L
F
T
I
----------
E
L
A
A
L
F
H
---------
D
Y
S
-
D
----------------------------------------------------------------------------------------
Q
E
A
T
----
K
T
------
L
I
N
W
M
-
E
T
K
--
E
I
P
S
E
-
L
I
K
K
I
I
R
I
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-------
Q
S
V
-
S
------------------------------
A
L
T
I
E
E
K
---
I
V
Q
D
A
D
R
L
D
A
I
---
G
A
-------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
54.93
15%
-102
- C6 -
-
5DQV
-
?
B:
[7-138]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
E
L
K
Q
A
D
Q
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---
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---------------
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-------
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H
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--
S
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R
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-------
L
A
V
Y
I
G
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--
K
E
N
--
A
D
L
F
I
V
----------
E
T
A
A
L
V
H
---------
D
L
I
-
D
----------
V
K
L
----
P
--------------------------------------------------
T
------------------
I
R
L
S
V
----
S
E
------
V
Y
N
Q
L
-
V
T
F
--
G
I
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K
E
-
D
A
D
R
V
I
H
I
I
-------
T
K
M
-
S
F
R
D
R
---------------------------
L
S
I
E
G
K
---
V
V
Q
D
A
D
R
L
D
A
I
---
G
A
V
------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
54.44
15%
-93
- C6 -
-
5IHY
-
?
B:
[8-138]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
L
K
Q
A
D
Q
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---
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---------------
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-------
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H
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--
S
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R
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A
D
-------
L
A
V
Y
I
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--
K
E
N
--
A
D
L
F
I
V
----------
E
T
A
A
L
V
H
---------
D
L
I
-
D
----------
V
K
L
----
P
-------------------------------------------------
D
T
------------------
I
R
L
S
V
----
S
E
------
V
Y
N
Q
L
-
V
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F
--
G
I
G
K
E
-
D
A
D
R
V
I
H
I
I
-------
T
K
M
-
S
F
R
D
R
E
KLEG--------------------
E
P
L
S
I
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K
---
V
V
Q
D
A
D
R
L
D
A
I
---
G
A
V
------------------------------------------------------------------------------------------------------------------------------
23
Fugue
53.15
16%
-8
* C5 *
-
5TPI
-
?
A:
[7-211]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
L
F
S
L
G
S
----------------
L
E
-------
S
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A
A
V
R
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P
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T
L
A
H
F
-----
N
Q
R
Y
P
K
I
H
L
A
L
S
T
G
--------------------------------------------
P
S
G
T
M
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V
---
L
E
G
A
L
S
----------------------------------------------
A
A
F
-------
V
D
G
P
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V
H
PG
L
E
G
L
P
V
F
P
E
E
M
----------
M
I
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A
P
Y
G
---------
H
A
P
-
I
----------
T
R
A
----
S
E
------
V
---
N
--------------
G
-----------
A
---------
N
V
Y
------------------
A
F
R
A
N
----
C
S
------
Y
R
R
H
F
-
E
S
W
--
F
H
A
D
R
A
T
P
G
R
I
H
E
M
E
-------
S
Y
H
G
M
L
A
C
V
I
------------------------
A
G
A
G
L
A
L
I
P
R
S
M
L
E
S
M
P
G
H
Q
Q
V
---
S
A
W
P
L
-------
A
-----
E
---
E
W
R
-
W
L
--------
T
T
W
L
V
W
R
------
R
G
A
K
---
T
-----
R
Q
L
E
A
F
I
A
L
L
N
E
D
R
Q
T
-
V
V
S
P
----------------------------------------------
17
HHSearch
52.53
16%
-36
- C6 -
-
3CCG
-
?
A:
[5-186]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
K
I
---
T
D
Y
L
M
N
N
---------------
L
----
G
E
K
R
Y
K
H
S
--
L
-------------
G
V
M
D
-------
T
A
V
R
L
A
G
--
I
Y
N
E
D
--
T
E
K
A
----------
R
I
A
G
L
V
H
---------
D
C
A
-
K
----------
K
L
P
----
G
E
K
I
----
I
E
I
C
T
N
---------
E
---
G
Y
E
L
G
D
E
D
I
R
N
S
Y
----------
L
H
------------------
G
L
--------
A
------
G
R
I
L
A
-
K
K
V
I-
G
I
D
D
----
E
D
V
L
N
A
I
-------
E
F
H
-
T
T
G
R
P
--------------------------
N
M
S
L
L
E
K
---
I
I
Y
I
A
D
Y
I
E
P
G
---
R
E
F
K
G
V
D
E
L
R
K
A
A
-----
D
E--
D
L
N
K
A
L
--------
L
M
S
F
--
D
N
T
I
K
F
V
I
D
K
G
---
G
-----
F
L
H
H
N
T
I
E
A
R
N
Y
L
I
-----------------------------------------------------
13
HHSearch
50.73
15%
-18
- C6 -
-
2O08
3
?
B:
[6-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
---
L
Q
L
V
K
P
H
---------------
L
----
T
E
H
R
Y
Q
H
T
--
I
-------------
G
V
M
E
-------
T
A
I
D
L
A
K
--
L
Y
G
A
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--
Q
Q
K
A
----------
E
L
A
A
I
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H
---------
D
Y
A
-
K
----------
F
R
D
----
K
N
EMR---
T
---
L
----------
I
---
R
-----------
E
KLSQQDILF
Y
G
D
------------------
E
L
L
H
A
----
P
C
------
G
A
Y
Y
V
R
E
E
V
--
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E
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----
E
D
V
L
Q
A
I
-------
R
F
H
-
T
T
G
R
P
--------------------------
N
M
S
L
L
E
K
---
I
I
F
L
A
D
Y
I
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P
N
---
R
Q
F
P
G
-------
V
EKVRT
Q
AKT
D
L
N
G
A
I
ISSLVNTI
T
F
L
L
--
K
-------
K
-
N
---
Q
-----
P
I
Y
P
D
T
L
A
T
Y
N
Q
L
L
L
E
---------------------------------------------------
9
HHSearch
50.70
16%
-66
- C6 -
-
3DTO
-
?
B:
[4-132]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
I
L
Q
S
A
---
E
A
W
V
K
K
Q
---------------
L
MDE----
D
W
Y
H
I
--
R
-------------
R
V
T
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-------
M
A
K
A
I
G
E
--
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E
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--
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D
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F
V
V
----------
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A
A
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F
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---------
D
L
I
-
D
----------------------------------------------------------------------------------------
E
T
A
K
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Q
------
L
I
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W
M
-
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A
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--
G
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P
S
Q
-
K
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D
H
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M
D
I
I
-------
N
T
I
---------------------------------
A
T
R
E
A
M
---
V
V
Q
D
A
D
R
L
D
A
L
---
G
A
I
------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
47.78
14%
-39
- C6 -
-
3DJB
-
?
B:
[4-142]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
K
I
E
K
T
---
I
T
F
V
K
H
I
---------------
L
EKDA
S
G
H
D
W
Y
H
I
--
R
-------------
R
V
H
K
-------
M
A
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S
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S
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--
Q
E
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--
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N
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F
I
I
----------
E
M
A
A
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L
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---------
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V
A
-
D
------------
L
----
N
-------------------------------------------------
E
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------------------
E
E
A
G
M
----
K
K
------
V
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-
E
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--
H
V
E
E
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I
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-------
A
N
M
-
S
---------------------------------
I
E
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K
---
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A
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A
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A
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27
Fugue
47.60
18%
17
* C7 *
-
4U0O
4
LIPA2_THEEB
B:
[8-288]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
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CPNRGEC
Y
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T
-----
C
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A
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PDQGAGQ
F
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MDRGRL---
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Y
NHNLETVRRLQGPVRRGA
T
Y
E
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R
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N
P
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E
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Y
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----------------------
24
Fugue
45.37
13%
27
- C3 -
-
1O89
-
ACUI_ECOLI
A:
[1-323]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQALLLEQQT
L
A
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T
L
D
ESRLPEGDVTVD
V
H
W
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S
L
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N
Y
K
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WGVGENHWGGL
A
E
Q
-------------------------
A
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V
K
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D
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A
M
---
P
Q
G
L
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A
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--
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A
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--
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E
I
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GASG
G
V
G
S
T
A
V
A
L
L
H
---------
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L
G
-
Y
Q
V
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A
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GRES
T
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------
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-----------
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P
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FAES
R
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MNYG
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L
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-
R
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LP
E
-----
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V
-----------------------------
8
HHSearch
44.29
17%
-13
- C6 -
-
2QGS
-
?
A:
[4-131]
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R
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---
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QHDT
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--
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-------
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L
K
Q
F
L
-
S
T
L
--
D
L
S
S
E
-
I
S
Q
Q
V
L
Y
I
I
-------
K
H
M
-
S
-----H-----------------------
V
K
L
S
I
D
G
E
---
I
V
R
D
A
D
R
L
D
A
I
---
G
A
I
------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
43.64
14%
-13
- C6 -
-
4S1B
2
PGPH_LISM4
A:
[15-195]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
G
T
Y
H
H
S
--
M
-------------
M
V
A
N
-------
L
A
E
A
C
A
D
--
K
I
G
A
--
N
S
L
L
V
----------
R
V
G
C
F
Y
H
---------
D
I
G
-
K
----------
T
L
R
----
P
P
------
Y
---
F
VENQINP---
H
DRL
T
P
E
---------
Q
S
--------
R
D
I
------------------
I
L
S
H
T
----
K
D
------
G
A
E
I
L
-
K
E
N
--
H
M
-----
P
Q
P
I
I
D
I
A
-------
L
Q
H
-
H
G
T
T
L
L
K
Y
F
Y
F
K
A
K
ETNPDVKEADYRYSGP
K
P
Q
T
K
E
I
A
---
I
I
N
I
S
D
S
V
E
A
A
---
V
R
S
S
T
-------
E
-----
P
---
T
M
A
-
K
I
--------
T
E
I
I
--
D
------
G
I
I
K
D
--
R
-----
F
L
D
G
Q
F
T
E
C
D
I
T
-------------------------------------------------------
19
HHSearch
41.48
15%
11
- C6 -
-
2OGI
2
?
B:
[13-170]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
L
---
L
S
K
V
R
H
M
---------------
M
----
S
D
K
R
F
N
H
V
--
L
-------------
G
V
E
R
-------
A
A
I
E
L
A
E
--
R
Y
G
Y
D
--
K
E
K
A
----------
G
L
A
A
L
L
H
---------
D
Y
A
-
K
----------
E
L
S
----
D
D
E
F
L
---
R
---
L
----------
I
---
D
K
YQPD
P
D
L
K
--
K
---------
W
G
N
------------------
N
I
W
H
G
----
L
V
------
G
I
Y
K
I
Q
E
D
L
--
A
I
K
D
----
Q
D
I
L
A
A
I
-------
A
K
H
-
T
V
G
S
A
--------------------------
Q
M
S
T
L
D
K
---
I
V
Y
V
A
D
Y
I
E
H
N
---
R
D
F
---------------------
P
-
G
V
--------
E
E
A
R
--
E
------
L
-
A
K
---
V
-----
D
L
N
K
A
V
A
Y
E
T
A
R
T
V
-----------------------------------------------------
18
HHSearch
40.63
15%
7
* C6 *
-
2OGI
1
?
A:
[13-170]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
L
---
L
S
K
V
R
H
M
---------------
M
----
S
D
K
R
F
N
H
V
--
L
-------------
G
V
E
R
-------
A
A
I
E
L
A
E
--
R
Y
G
Y
D
--
K
E
K
A
----------
G
L
A
A
L
L
H
---------
D
Y
A
-
K
----------
E
L
S
----
D
D
E
F
L
---
R
---
L
----------
I
---
D
K
YQPD
P
D
L
K
--
K
---------
W
G
N
------------------
N
I
W
H
G
----
L
V
------
G
I
Y
K
I
Q
E
D
L
--
A
I
K
D
----
Q
D
I
L
A
A
I
-------
A
K
H
-
T
V
G
S
A
--------------------------
Q
M
S
T
L
D
K
---
I
V
Y
V
A
D
Y
I
E
H
N
---
R
D
F
---------------------
P
-
G
V
--------
E
E
A
R
--
E
------
L
-
A
K
---
V
-----
D
L
N
K
A
V
A
Y
E
T
A
R
T
V
-----------------------------------------------------
29
Fugue
38.49
21%
25
- C7 -
-
4S3Q
3
MALQ_ECOLI
A:
[2-691]
ES
K
R
L
D
N
A
A
L
A
A
GISP
N
Y
I
N
AHG
K
P
Q
S
I
S
A
E
T
K
R
R
L
L
D
A
MHQTPVPN
V
M
V
Y
T
S
G
K
K
M
P
M
V
V
E
G
S
G
E
Y
S
W
L
L
T
T
EEG
T
Q
Y
K
G
H
V
T
GG
K
A
F
N
L
P
TKLPE
G
Y
H
T
L
T
L
T
Q
DD
Q
R
A
H
C
R
V
I
V
A
P
KRCYEP
Q
A
L
L
N
K
Q
K
L
W
G
A
C
V
QLYTLRSEKNWGIGD
F
G
D
L
K
A
M
L
V
D
V
A
K
R
GGS
F
I
G
L
N
PIHALYPANPESASPYSPSSRRWLNVIYIDVNAV
E
D
F
H
L
S
E
E
A
Q
A
W
W
Q
L
P
T
T
Q
Q
T
L
Q
Q
A
R
D
ADWVD
Y
S
T
V
T
A
L
K
M
T
A
L
R
M
A
W
K
G
F
A
Q
RDD
E
Q
M
A
A
F
R
Q
F
V
A
E
Q
G
D
S
L
F
W
Q
A
A
F
D
A
L
H
A
Q
Q
V
K
E
DEMRWGWPAWP
E
M
Y
Q
N
V
DS
P
E
V
R
Q
F
C
E
E
H
R
D
D
V
D
F
Y
L
W
L
Q
W
L
A
Y
S
Q
F
A
A
C
W
E
I
S
Q
G
Y
EMPIG
L
Y
R
D
L
A
VGVAEGG
A
E
T
W
C
D
RELYCLK
A
S
V
G
A
P
PDILGPLGQNWG
L
P
P
M
D
P
H
I
I
T
A
R
AY
E
P
F
I
E
L
L
R
A
N
M
QNCG
A
L
R
I
D
HVMSMLRLWWIPYGETADQ
G
A
Y
V
H
Y
P
V
D
D
L
L
S
I
L
A
L
E
S
K
R
H
R
C
M
V
I
G
E
D
L
G
T
V
P
V
E
-------
I
V
G
K
L
R
S
S
G
V
Y
-
S
Y
-----
K
V
L
Y
F
E
N
D
H
E
K
T
F
R
A
-------------
P
K
A
--------------------------
Y
P
E
Q
S
M
A
V
A
A
---
T
H
D
L
P
T
-------------------------------
L
-------------
R
G
Y
W
-------
E
C
G
D
L
T
L
--
G
K
T
L
G
L
Y
P
D
E
V
----------
V
L
R
G
L
Y
Q
---------
D
R
E
-
L
----------
A
K
Q
G
L
L
D
A
L
------
H
---
K
----------
Y
---
G
-----------
C
---------
L
------------------------
P
----
K
R
------
A
G
H
K
A
-
S
L
M
--
S
M
T
---------
P
T
L
-------
N
R
G
-
L
Q
R
Y
I
A
------------------------
D
S
N
S
A
-
L
L
---
G
L
Q
---------------------------------
P
E
D
-
W
L
--------
D
-----
M
------
A
E
P
V
---
N
-----
I
P
G
T
S
Y
-
Q
Y
K
N
W
R
R
K
L
-
S
A
T
-----------
L
E
S
M
F
A
D
--
D
G
V
N
K
L
L
K
D
L
D
R
R
R
R
S
AH---------
31
Fugue
38.37
17%
-21
- C5 -
-
5LQC
1
COMT_RAT
A:
[4-216]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
E
Q
R
I
L
R
Y
V
Q
Q
N
A
K
P
G
D
---------------------
P
Q
S
V
L
E
A
I
-----
D
T
Y
C
T
Q
K
E
W
A
M
N
V
G
D
-------------
A
K
G
-------------------------
Q
I
M
D
A
V
I
R
E
Y
S
PS
L
V
L
E
L
G
A
Y
---------------
C
----
G
Y
S
A
V
R
M
A
----------------
R
L
L
Q
-------
P
G
A
R
L
L
T
--
M
E
M
N
--
P
D
Y
A
A
----------
I
T
Q
Q
M
L
N
---------
F
A
G
-
L
----------
Q
D
K
-------------------------------------------
V
---------
T
I
L
------------------
N
G
A
S
Q
----
D
L
------
I
P
Q
L
K
-
K
K
Y
--
D
V
D
T
L
-------
D
M
V
-------
F
L
D
-
H
W
---
K
------------------------
D
R
Y
L
P
D
T
L
---
L
L
E
K
---
C
G
L
L
---
R
K
G
T
V
-------
L
-----
L
---
A
----
D
--------
N
V
I
V
--
P
------
G
T
--------------
P
D
F
L
A
Y
V
R
G
S
S
S
F
-
E
C
T
H
Y
S
S
-
Y
L
E
Y
M
K
V
V
D
G
L
E
K
--
A
I
Y
Q
G
P
S
--------------------
15
HHSearch
37.57
14%
-18
- C6 -
-
4S1B
2
D:
[15-195]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
G
T
Y
H
H
S
--
M
-------------
M
V
A
N
-------
L
A
E
A
C
A
D
--
K
I
G
A
--
N
S
L
L
V
----------
R
V
G
C
F
Y
H
---------
D
I
G
-
K
----------
T
L
R
----
P
P
------
Y
---
F
VENQLQGINP
H
DRL
T
PE---------
Q
S--------
R
D
I
------------------
I
L
S
H
T
----
K
D
------
G
A
E
I
L
-
K
E
N
--
H
M
-----
P
Q
P
I
I
D
I
A
-------
L
Q
H
-
H
G
T
T
L
L
KYFYFKAKETNPDVKEADYRYSGP
K
P
Q
T
K
E
I
A
---
I
I
N
I
S
D
S
V
E
A
A
---
V
R
S
S
T
-------
E
-----
P
---
T
M
A
-
K
I
--------
T
E
I
I
--
D
------
G
I
I
K
D--
R
-----
F
L
D
G
Q
F
T
E
C
D
I
T
-------------------------------------------------------
12
HHSearch
35.81
18%
-51
- C6 -
-
3GW7
-
YEDJ_ECOLI
B:
[5-137]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
W
Q
A
Q
F
---
E
N
W
L
K
N
H
------------------------
V
C
H
F
--
R
-------------
R
V
W
A
-------
T
A
Q
K
L
A
A
--
D
D
D
--
V
D
M
L
V
I
----------
L
T
A
C
Y
F
H
---------
D
I
V
-
S
------------------------------------------------------------------
Q
R
S
------------------
S
I
L
A
A
----
E
E
------
T
R
R
L
L
-
R
E
E
FE
Q
F
P
A
E
-
K
I
E
A
V
C
H
A
I
-------
A
A
H
-
S
F
S
A
Q
I
------------------------
A
P
L
T
T
E
A
K
---
I
V
Q
D
A
D
R
L
E
A
L
---
G
A
-------------------------------------------------------------------------------------------------------------------------------
22
Fugue
34.54
17%
5
- C2 -
-
2V4J
4
DSVB_DESVH
B:
[2-381]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AFISSGYNPEKPMA
N
R
I
T
D
I
G
P
R
K
F
D
E
F
F
P
P
V
I
A
K
N
F
G
S
W
-------
L
Y
H
E
I
L
E
P
G
V
L
M
H
V
A
ESG
D
K
V
Y
T
V
R
V
G
A
A
R
L
M
S
I
-------------
T
H
I
R
E
M
C
D
I
A
D
K
YCGG
H
L
R
F
T
TRN
N
V
E
F
M
V
A
D
E
A
S
L
K
A
L
---
K
E
D
L
A
S
R
KFDGGSLK
F
P
I
G
GTG
A
----
G
V
S
N
I
V
H
T
QG
W
VHCHTPATDA
S
G
P
V
K
A
I
-------
M
D
E
V
F
E
D
--
F
Q
S
M
R
L
P
A
P
V
R
----------
I
S
L
A
C
C
I
NMCGAVHCS
D
I
G
-
V
----------
V
G
I
----
H
R
KPPMID
H
---
E
----------
W
---
T
-----------
D
---------
Q
L
C
------------------
E
I
P
L
A
----
V
A
S
CPTAA
V
R
P
T
K
-
L
E
I
--
G
D
K
K
V
-
N
T
I
A
I
K
N
E
R
-------
C
M
Y
-
C
-
G
N
C
Y
------------------------
T
M
C
P
A
L
P
I
---
S
D
G
E
G
D
G
V
V
I
M
V
GG
K
V
S
N
R
-------
I
-----
S
---
M
P
K
-
F
S
--------
K
V
V
V
--
A
------
Y
I
P
N
---
E
PPRW
P
S
L
T
K
T
I
K
H
I
I
E
V
Y
S
A
N
A
Y
K
Y
E
R
L
G
E
W
A
E
R
I
G
W
E
R
F
F
S
L
T
G
L
E
F
S
H
H
L
I
DDFRDPAYYTWRQSTQFKF
28
Fugue
31.62
10%
15
- C6 -
-
4N6W
-
?
A:
[39-225]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-------------------------
S
L
S
N
S
S
K
V
S
V
L
---
I
S
L
L
E
K
S
---------------
R
----
D
L
D
Y
I
G
E
A
--
I
-------------
N
Q
L
E
-------
H
S
L
Q
C
A
Y
--
F
A
Q
R
S
G
A
D
N
E
M
----------
V
L
A
A
L
L
H
---------
D
L
G
H
Y
----------
C
N
G
----
G
Y
------
G
---
V
----------
W
---
Q
---------------------------------------------
H
E
----
K
V
------
G
A
D
Y
L
-
R
G
L
--
G
F
S
E
R
-
V
A
C
L
I
E
--
G
-------
H
V
A
-
A
K
R
Y
L
V
------------------------
S
S
K
A
S
Y
L
K
---
N
L
S
D
A
S
R
K
T
L
E
---
Y
Q
G
G
--------------------
P
-
M
D
--------
E
G
E
R
--
R
------
L
F
E
E
---
R
-----
E
D
F
K
D
C
L
K
I
R
A
W
D
E
K
G
-
K
Q
T
D
L
K
V
-
P
G
P
E
H
Y
R
K
M
M
E
E
H
--
L
S
E
------------------------