@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : B0VKG8: (2017-10-26 )
MNTFVDAARSFRTQFDLNFSEKIIVDFFAGGGGASTGLEMGLNRPVYVAVNHNPKAISMHEANHPHAKHYIQDVFAVDPIDICDGHQVGWFHASPDCTHHSQAAGGQPRKKEIRDLSWVVLKFAGKVKPDVISLENVKQILGWGPLIAKRDKATGRVITLDKININGKKVNRIAEPGERVPRHNQFLVPNPKKKGKTWKHFVRSLEQLGYEVEWQKNIIAADFGAPTKRERLFLIARCDGQPIVWPEKYFSKKPKGNLKKWRSTVECVDFSDLGNSIFDRPQGPLADATLKRIAKGIQKYVIETKEPFFVNSSTPFIGRDFRTSFGHDIREPLATTTAGYGGHSSLISPILVPFITEFANASQQRNWSIDEPLSTICAQVKGGHHGLVTAKLSKDNYKGALRVAAFLINYYGNGDARSITEPMDTITTKDRLVLVTVWIKGEPWAIVDICIRMLKPRELFRAQGVPDSYVIEYGSDGKPLSKKDQVFMVGNSVSPYPMAAIARANNPFITQQIKGAA

Atome Classification :

(20 SA) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10....------....20.-----.....----------..30...--.....40..-----..--..---...50---.........60.---..---..---..-----.70.......-----------------------------------------.------------80-----------..-------------.-...------------...90....------....100..--...-------..--110-------....--..-----..120-..------.--..--------..130--.........140.......150.....------..160.......170......----..180...----....190.-----......200-..--.....210.-.---------.-------..-------..220.......230......----.240---------.----.---...----..250..---.---------------------.----...260.----......270---.........280.......290....----..-.300.......310.........320.....-..330.......340------.------......350-...---------......360........370.......380.-......----------------------------------------------------390-------------------------------------------------.........400-......-..410.......--.420.......430.......----440........450----....--....460-.---...-...470.....--..480--.....--....------490.......500.......510.....------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTFVDAARSFRTQF------DLNFSEK-----IIVDF----------FAGGGGA--STGLEM-GL-----NR--PV---YVAV----NHNPKAISMHEA---NH---PH---AK-----HYIQDVFAVD-----------------------------------------P------------I------------DI-------------C-DGH------------QVGWFHASP------DCTHHSQAA--GGQ-------PR--K-K-------EIRD--LS-----WVVLK-FA------G--KV--------KPD----VISLENVKQILGWGPLIAKRDKATGRV------ITLDKININGKKVN-RIAEPG----ERVPRHNQ----FLVPNPKK-----KGKTWKHFV-RS--LEQLGYEVE-W---------Q-------KN-------IIAADFGAPTKRERLFLIARC----DGQP---------I----V---WPE----KYFSKKP---K---------------------G----NLKKWRS----TVECVDF-----SDLGNSIFDRPQGPLADATLKRIAKG----IQ-KYVIETKEPFFV--NSSTPFIGRDFRTSFGH-DIREPLATTTAGYGG------H------SSLISPI---LVP---------FITEFANA-SQQRNWSIDEPLSTICAQVKGG-HHGLVT----------------------------------------------------A---------------------------------------------------KLSKDNYKGAL--RVAAFL-INYY-GNGDARS--ITEPMDTITTKDRLVLVTVWI----KG-EPWAIVDICI-----RMLK--PRELFRA-Q---GVP-DSYVIEYGSDG--KPL----SKKDQ--VFMV------GNSVSPYPMAAIARANNPFITQQIKGAA------
22 HHSearch 75.8919% -2 - C6 - - 3PT9 DNMT1_MOUSE A:[409-871] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPKL-----RTLDV----------FSGCGGL--SEGFHQ-A------GIS-ET---LWAI----EMWDPAAQAFRL---NN---PG---TT-----VFTEDCNVLL-----------------------------------------KLVMAGEVTNSLGQ------------RL-------------P-QKG------------DVEMLCGGP------PCQGFSGMN--RFN-------SRTYS-K-------FKNS--LV-----VSFLS-YC------D--YY--------RPR----FFLLENVRNFVSYRR---------------------------------------------------------------------SMVLKLTL-RC--LVRMGYQCT-F---------G-------V--------LQAGQYGVAQTRRRAIILAAA----PGEK---------LP---L---FPE----PLHVFAP---RACQLSVVVDDKKFVSNITRLSS----GPFRTIT----VRDTMSD-----LPE-IQNGAS-NSEI------------------------------------------------P-YNGEPLSWFQRQLRGSHYQPIL------RDHICKD---MSP---------L----------VAARMRHIPLFPG------S-DWRDLP----------------------------------------------------NIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPWCLPHTG--NRHNHW-AGLY-G---RLE--WDGFFSTTVTNPE-----PMG----K--QGRVLHPEQH-----RVVS--VRECARS-Q---GFP-DSYRFF--------GN-----ILDR--HRQV------GNAVPPPLAKAIGLEIKLCLLS------------
21 HHSearch 74.6818% 11 - C6 - - 3SWR DNMT1_HUMAN A:[537-1001] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPKL-----RTLDV----------FSGCGGL--SEGFHQ-A------GIS-DT---LWAI----EMWDPAAQAFRL---NN---PG---ST-----VFTEDCNILL-----------------------------------------K------------LVMAGETTNSRGQRL-------------P-QKG------------DVEMLCGGP------PCQGFSGMN--RFN-------SRTYS-K-------FKNS--LV-----VSFLS-YC------D--YY--------RPR----FFLLENVRNFVSFKR---------------------------------------------------------------------SMVLKLTL-RC--LVRMGYQCT-F---------G-------V--------LQAGQYGVAQTRRRAIILAAA----PGEK---------LP---L---FPE----PLHVFAP---RACQLSVVVDDKKFVSNITRLSS----GPFRTIT----VRDTMSD-----LPE-VRNGAS-ALEIS-------------------------------------------------YNGEPQSWFQRQLRG------AQYQPILRDHICKD---MSA---------L----------VAARMRHIPLAPG------S-DWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFN---------------------------------------------------TLIPWCLPHTG--NRHNHW-AGLY-G---RLE--WDGFFSTTVTNPE-----PMG----K--QGRVLHPEQH-----RVVS--VRECARS-Q---GFP-DTYRLF--------GN-----ILDK--HRQV------GNAVPPPLAKAIGLEIKLCMLAK-----------
46 Fugue 72.4821% -69 - C6 - - 6MHT MTH1_HAEPH A:[1-327] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIEIK------DKQLTGL-----RFIDL----------FAGLGGF--RLALES-C------GA--EC---VYSN----EWDKYAQEVYEM---NF---G-----E-----KPEGDITQVN-----------------------------------------E------------K------------TI-----------------P------------DHDILCAGF------PCQAFSISG--KQK-------GF--E-D-------SRGT--LF-----FDIAR-IV------R--EK--------KPK----VVFMENVKNFA----------------------------------------------------------------SHD-----NGNTLEVVK-NT--MNELDYSFH-A---------K-------VL-------N-ALDYGIPQKRERIYMICFR---------------------------------------------------------------------------------------------NDLNIQNFQFPKPFELNTFVKDLLLP-------------------------------------------------------------------------------------------DSEVEH-LVIDRKDLVMTNQEIEQTTPKT-VRLGIV----------------------------------------------------G---------------------------------------------------KGGQGERIYST--RGIAIT-LSAY-GGGIFAK--TGGYLVN-------------------G-K--------T-----RKLH--PRECARV-M---GYP-DSYKVH-PS------------TSQA--YKQF------GNSVVINVLQYIAYNIGSSLNFKPY---------
23 HHSearch 71.3719% 5 - C6 - - 4DA4 DNMT1_MOUSE A:[409-871] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPKL-----RTLDV----------FSGCGGL--SEGFHQ-A------GIS-ET---LWAI----EMWDPAAQAFRL---NN---PG---TT-----VFTEDCNVLL-----------------------------------------KLVMAGEVTNSLGQ------------RL-------------P-QKG------------DVEMLCGGP------PCQGFSGMN--RFN-------SRTYS-K-------FKNS--LV-----VSFLS-YC------D--YY--------RPR----FFLLENVRNFVSYRR---------------------------------------------------------------------SMVLKLTL-RC--LVRMGYQCT-F---------G-------V--------LQAGQYGVAQTRRRAIILAAA----PGEK---------LP---L---FPE----PLHVFAP---RACQLSVVVDDKKFVSNITRLSS----GPFRTIT----VRDTMSD-----LPE-IQNGAS-NSEI------------------------------------------------P-YNGEPLSWFQRQLRGSHYQPIL------RDHICKD---MSP---------L----------VAARMRHIPLFPG------S-DWRDLP----------------------------------------------------NIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPWCLPHTG--NRHNHW-AGLY-G---RLE--WDGFFSTTVTNPE-----PMG----K--QGRVLHPEQH-----RVVS--VRECARS-Q---GFP-DSYRFF--------GN-----ILDR--HRQV------GNAVPPPLAKAIGLEIKLCLLS------------
29 HHSearch 68.7321% -47 - C6 - - 5CIY MTH1_HAEPH A:[8-325] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLTGL-----RFIDL----------FAGLGGF--RLALES-C------GA--EC---VYSN----EWDKYAQEVYEM---NF---GE---K-------PEGDITQVN-----------------------------------------E------------K------------TI-----------------P------------DHDILCAGF------PCQAFSISG--KQK-------GF--E-D-------SRGT--LF-----FDIAR-IV------R--EK--------KPK----VVFMENVKNFASHD---------------------------------------------------------------------NGNTLEVVK-NT--MNELDYSFH-A---------K-------V--------LNALDYGIPQKRERIYMICFR----NDLN---------IQNF-Q---FPK----PFEL-------------------------------------NTF----VKDLLLP-----DSE---V-----EHL---VIDRK----------DLVM--T-----------NQE----------------IEQ-----------------------TTPK--------------------------------TVRLGIVGK-----------------------------------------------------------------------------------------------------------------------------------------GGQ--GERIYS--TRGIAITLSAYGGGIF----A----K--TGGYLVNGKT-----RKLH--PRECARV-M---GYP-DSYKVH--------PS-----TSQA--YKQF------GNSVVINVLQYIAYNIGSSLNFK-----------
26 HHSearch 68.0822% -47 - C6 - - 2I9K MTH1_HAEPH A:[8-324] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLTGL-----RFIDL----------FAGLGGF--RLALES-C------GA--EC---VYSN----EWDKYAQEVYEM---NF---GE---K-------PEGDITQVN-----------------------------------------E------------K------------TI-----------------P------------DHDILCAGF------PCQAFSISG--KQK-------GF--E-D-------SRGT--LF-----FDIAR-IV------R--EK--------KPK----VVFMENVKNAASHD---------------------------------------------------------------------NGNTLEVVK-NT--MNELDYSFH-A---------K-------V--------LNALDYGIPQKRERIYMICFR----NDLN---------IQNF-Q---FPK----PFEL-------------------------------------NTF----VKDLLLP-----DSE---V-E----HL---VIDRK--D----L----VM--------------T-N-------------QEIEQT------------------------TPK---------------------------T-----VRLGIV--GK---------------------------------------------------------------------------------------------------------------------------------------GGQ--GERIYS--TRGIAITLSAYGGGI----FA----K--TGGYLVNGKT-----RKLH--PRECARV-M---GYP-DSYKVH--------PS-----TSQA--YKQF------GNSVVINVLQYIAYNIGSSLNF------------
25 HHSearch 65.5920% -20 * C6 * - 3G7U ? A:[2-369] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SL-----NVIDL----------FSGVGGL--SLGAAR-A------GF--DV---KMAV----EIDQHAINTHAI---NF---PR---SL-----HVQEDVSLLN-----------------------------------------A------------E------------IIKGFF---------K-NDM------------PIDGIIGGP------PCQGFS-------------------D-D-------SRNQ--LY-----MHFYR-LV------S--EL--------QPL----FFLAENVPGIMQEKY----------------------------------------------------------------------SGIRNKA-FN--LVSGDYDILDP---------I-------K--------VKASDYGAPTIRTRYFFIGVK----KSLK---------L----D---ISD----EVFMP--------------------------------KMIDPVT----VKDALYG-----LPD-IIDAN---WQSDSESWRTIKKD----RKGGFYEK---------------L-----------WGQIPRNVGD----T------E--------SI-AK---LKN--------------------NIISGCTGT------------LHS-----------------------------------------------------------------------------------------------------------KIVQERYA--S----LSFGETDKI-SRSTRLD--PNGFCPTL---------------------VRPIHPYHP-----RVIT--PREAARL-Q---GFP-DWFRFH--------VT-----KWHS--FRQI------GNSVSPIVAEYILKGLYNLLNE------------
45 Fugue 62.9316% -2 - C6 - - 3AV4 - DNMT1_MOUSE A:[67-1322] PKCPECGQHLDDPNLKYQQHPEDAVDEPQMLTSEKLSYEDSPMHRFTSFSVYCSRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGINGKNLGPINQWWLSGFDGGEKVLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIVVEFLQNNPDAVYEDLINKIETTVPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDDETPIFLSPCMRALIHLAGVSLGQRRATRAPTKATTTKLVYQIFDTFFSEQIEKRRRCGVCEVCQQPACLKRRCPNLAVKEADDDEEADDEMPSPKKLHQGKKKKQNKDRISWLGQPMKIERTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSCIRLAELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVKKDPVNETLYPEHYRKYSLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHA------RSKLPKL-----RTLDV----------FSGCGGL--SEGFHQ-AG-----IS--ET---LWAI----EMWDPAAQAFRL---NN---PG---TT-----VFTEDCNVLL-----------------------------------------K------------LVMAGEVTNSLGQRL-------------P-QKG------------DVEMLCGGP------PCQGFSGMN--RFN-------SR--T-Y-------SKFKNSLV-----VSFLS-YC------D--YY--------RPR----FFLLENVRNFV----------------------------------------------------------------SYR-----RSMVLKLTL-RC--LVRMGYQCT-F---------G--------V-------LQAGQYGVAQTRRRAIILAAA----PGEK---------L----P-----------LFPEPL---H---------------------V----FAPRACQ----LSVVVDD-----KKFVSNITRLSSGPFRTITVRDTMSD----LP-EIQNGASNSEIPYNGEPLSWFQRQLRGSHYQ-PILRDHICKDMSPLV------A------ARMRHIP---LFPGSDWRDLPNIQVRLGDG-VIAHKLQYTFHDVKNGYSSTGA-LRGVCS----------------------------------------------------C---------------------------------------------------AEGKACDPESR--QFSTLI-PWCL-PHTGNRH--NHWAGLYGRLEWDGFFSTTVT----NP-EPMGKQGRVLHPEQHRVVS--VRECARS-Q---GFP-DSYRFFG-------------NILDR--HRQV------GNAVPPPLAKAIGLEIKLCLLSSARESASAAVKA
44 Fugue 60.5616% 19 - C6 - - 3PT9 DNMT1_MOUSE A:[1-871] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSCIRLAELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPVKRPKKDPVNETLYPEHYRKYSLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHARSPG------I-KLPKL-----RTLDV----------FSGCGGL--SEGFHQ-AG-----IS--ET---LWAI----EMWDPAAQAFRL---NN---PG---TT-----VFTEDCNVLL-----------------------------------------K------------L------------VM-------------A-GEVTNSLGQRLPQKGDVEMLCGGP------PCQGFSGMN--RFN-------SR--T-Y-------SKFKNSLV-----VSFLS-YC------D--YY--------RPR----FFLLENVRNFVS----------------------------------------------------------------YR-----RSMVLKLTL-RC--LVRMGYQCT-F-----------------GV-------LQAGQYGVAQTRRRAIILAAA----PGEK---------L----PLFPEPL----HVFAPRA---C---------------------Q----LSVVVDD----KKFVSNI-----TRLSSGPFRTITVRDTMSDLPEIQNGASNSEI-PYNGEPLSWFQR--QLRGSHYQPILRDHICK-DMSPLVAARMRHIPL------F------PGSDWRD---LPN---------IQVRLGDG-VIAHKLQYTFHDVKNGYSSTGA-LRGVCS----------------------------------------------------C---------------------------------------------------AEGKACDPESR--QFSTLI-PWCL-PHTGNRHNHWAGLYGRLEWDGFFSTTVTNP----EP-MGKQGRVLHPEQH--RVVS--VRECARS-Q---GFP-DSYRFFG-------------NILDR--HRQV------GNAVPPPLAKAIGLEIKLCLLS------------
32 HHSearch 60.5017% -5 - C6 - - 4H0N ? B:[3-333] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SH-----KILEL----------YSGIGGM--HCAWKE-S------GLDGEI---VAAV----DINTVANSVYKH---NF---PE---TN-----LLNRNIQQLT-----------------------------------------P------------Q------------VI---------------KKW------------NVDTILMSP------PCQPFTRNG--KYL-------DD--N-D-------PRTN--SF-----LYLIG-IL------D--QLD-------NVD----YILMENVKGFENST------------------------------------------------------------------------VRNLFI-DK--LKECNFIYQ-E---------F-------L--------LCPSTVGVPNSRLRYYCTARR----NNLT------------------WPF----KRRDEIITRLP---------------------K----DFGVPHS----LESIIEE-----DVD-EK-------FLVPEKMLRCAKV----FD--ICY-------------------------------KT---------------------------------------------------------SKRSC-----CF-TK-----AYT---------------------------------------------------------------------------------------------------------------------------HYA--DGT-G---SIF--TDKPREVVQKCYAAAAQNEIG----GEKFVELFKELKL-----RYFT--PKEVLMI-M---CFP-KSYNLP--------TNI---SMKQC--YRLL------GNSVNVKVISELLKILFE----------------
27 HHSearch 58.8518% 37 - C6 - - 4DKJ ? A:[7-393] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIKVI-----KVFEA----------FAGIGSQ--FKALKN-IARSKNWEI--QH---SGMV----EWFVDAIVSYVA---IH---SK---NFNPKIERLDRDILSISNDSKMPISEYGIKKINNTIKASYLNYAKKHFNNLFDIKKVNK------------D------------NF----------------PK------------NIDIFTYSF------PCQDLSVQG--LQK-------GI--D-KELN----TRSG--LL-----WEIER-IL------E--EIKNSFSKEEMPK----YLLMENVKNLLSHK---------------------------------------------------------------------NKKNYNTWL-KQ--LEKFGYKSK-T---------Y-------L--------LNSKNFDNCQNRERVFCLSIR----DDYL---------EKTGFK---FKE----LEKV----------------------------------KNPPKK----IKDILVD-----SSN-YKYL-----NL-----NKYET------T-TFRET-------------KSN----------------------------------------------------------------------------IISRPLK----------NY---------------------------------------------------------------------------------------------------------------------------TTFN--SEN----YVYN--INGIGPTLTASGAN-----------S--RIKIETQQGV-----RYLT--PLECFKY-M---QFDVNDFKKV--------QSTNLISENKM--IYIA------GNSIPVKILEAIFNTLEFVNN-------------
28 HHSearch 55.9318% -98 - C6 - - 3UBT MTH3_HAEAE B:[1-188] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----NLISL----------FSGAGGL--DLGFQK-A------GF--RI---ICAN----EYDKSIWKTYES---NH---SA----K-----LIKGDISKIS-----------------------------------------S------------D------------EF-----------------P------------KCDGIIGGP------PSQSWSEGG--SLR-------GI--D-D-------PRGK--LF-----YEYIR-IL------K--QK--------KPI----FFLAENVKGMMAQRH---------------------------------------------------------------------NKAVQEFI-QE--FDNAGYDVH-I---------I-------L--------LNANDYGVAQDRKRVFYIGFR----KELN---------I----N---YLP----PIP-----------------------------------HLIKPT----FKDVIWD-----L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 HHSearch 54.9623% -26 - C6 - - 3LX6 - ? A:[83-327] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PHYAF-----RFIDL----------FAGIGGI--RRGFES-I------GG--QC---VFTS----EWNKHAVRTYKA---NH---YCDPATH-----HFNEDIRDIT-----------------------------------------L------------S------------HQEGVSDEAAAEHIRQ-HIP------------EHDVLLAGF------PCQPFSLA---------------A-C-D-------TQGT--LF-----FDVVR-II------D--AR--------RPA----MFVLENVKNLKSHD---------------------------------------------------------------------KGKTFRIIM-QT--LDELGYDVA-DAEDNGPDDPK-------I--------IDGKHF-LPQHRERIVLVGFR----RDLN---------LKA--D---FTL----RDISEC-------------------------------FPAQRVT----LAQLLDP-----MV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 HHSearch 54.4418%-100 - C6 - - 1DCT MTH3_HAEAE A:[1-188] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----NLISL----------FSGAGGL--DLGFQK-A------GF--RI---ICAN----EYDKSIWKTYES---NH---SA----K-----LIKGDISKIS-----------------------------------------S------------D------------EF-----------------P------------KCDGIIGGP------PCQSWSEGG--SLR-------GI--D-D-------PRGK--LF-----YEYIR-IL------K--QK--------KPI----FFLAENVKGMMAQRH---------------------------------------------------------------------NKAVQEFI-QE--FDNAGYDVH-I---------I-------L--------LNANDYGVAQDRKRVFYIGFR----KELN---------I----N---YLP----PIP-----------------------------------HLIKPT----FKDVIWD-----L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 HHSearch 53.0623% -38 - C- - - 3ME5 - ? A:[84-331] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HYAF-----RFIDL----------FAGIGGI--RRGFES-I------GG--QC---VFTS----EWNKHAVRTYKA---NH---YCDPATH-----HFNEDIRDIT-----------------------------------------L------------S------------HQEGVSDEAAAEHIRQ-HIP------------EHDVLLAGF------PCQPF---------------------CD-------TQGT--LF-----FDVVR-II------D--AR--------RPA----MFVLENVKNLKSHD---------------------------------------------------------------------KGKTFRIIM-QT--LDELGYDVA-DAEDNGPDDPK-------I--------IDGKHF-LPQHRERIVLVGFR----RDLN---------LKA--D---FTL----RDISEC-------------------------------FPAQRVT----LAQLLDP-----MV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48 Fugue 51.0018% 47 - C- - - 3ME5 - ? A:[15-466] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NAAQAMLEKLLQIYDVKMLVAQLNGVGENHWSAAILKRALALSEKEFAHLQTLL------PKPPEHHPHYAFRFIDL----------FAGIGGI--RRGFES-I------GG--QC---VFTS----EWNKHAVRTYKA---NH---YC---DP-----ATHHFNEDIR-----------------------------------------D------------I------------T--------------------------------------LS------HQEGVSDEA--AAE-------HI--R-Q-------HIPE--HD-----VLLAG-FP------C--QP--------FCD----T----------------------QGTL------FFDVVRIIDARRPAMFVLENV----KNLKSHD------------------KGKTFRI-IMQT--LDELGYDVA-D---------AEDNGPDDPK-------IIDGKHFLPQHRERIVLVGFR----------------------------------------------------------------------------------------------------------------------------------------------------RDLNLKADF-TLRDISECF------------------------PA---QRV---------TLAQLLDPMVEAKYILTPVLWKYLYRYAKKGMVYPNNP----------------------------------------------------Q---------------------------------------------------SVTRTLSARDG--AEILID-RGWDMATGEKDF--DDPLNQQHR----------------------------P-----RRLT--PRECARLMGFEAPGE-AKFRI---------PV----SDTQA--YRQF------GNSVVVPVFAAVAKLLEPKIKQAVALRQQEAQ--
51 Fugue 49.5118% 26 - C5 - - 5L8S - ? A:[1-604] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MINFPKPTVEQFFRTYTITNFAVSSDEKRLVF------NANLNGK-----MNLWAMDLPDTYPYLFAHRDES--CNFIKFDPE-----NR--YV---LAGFDKDGDENYQIYAIPNEGGLPH---PL---IT-----GDASEKYYFS-----------------------------------------H------------L------------SA---------------DGK------------CV-YYETSKENPSFLNTRIRNLET--GED-------RL--L-NVGEVSTTELAA--VSENEESFVYLR-AFANTYIVG--FV--------KMGEETFNITPDPEKVHVAMEPVFTDNETIYFATDYDSDEMYLAKFDLTSKEFS-KVLAFDGESIQSVKWDKDNKAFYLITVKGV-----TDILYRYDV-ATDKVEECSLPVD-I---------I-------EQ-------IQVA------KSGNLYILGRS----ATVPHNVYQSSNGV----E---WKQLTNNRVLGLSP---E---------------------DMVEPDIVSYTSFDGMEIEALLFKAKPENDNGYTIFWPHGGPQ----------S----AE-RKMFRSMFQCFI--NRGYTIFAPNFRGSTGYGSAFTKLVELDWGEGP------R------LDCIAGI---EWL---------FESGFTDR-NK--------------LFLVGG-SYGGYM----------------------------------------------------A---------------------------------------------------LLLHGRHSDYF--R---AV-VDIF-GPSDLFT--FINSVP----PHWKPIMERWLGDPERD-KERFIKDSPV-----TYLDGMVKPMLVI-Q---GAK-DPRVVKEESDQIVAKL----KEKGRDVEYLVLEDEGHGFSKKENEIKVYSLMLAFLEKHQALEHHHHHH--
53 Fugue 46.5619% 9 - C2 - - 5MF1 HAP2_CHLRE A:[4-561] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VIASGRLEKCVVDGVTEELDCQEK-----VVVTL----------TVGNGQSLQTEALEF-SL-----A---PL---RVSL----TKSPLWASYPLQ---YL---SS---FN-----WKPLEVILRP-----------------------------------------S------------N------------KV-------------CKDGD----------------WEDSP------TCGWFSQRV--ADSQGFCCECER--T-R-------ANLD--CD-----F---------------------------------------------WSPVSAHCLTFDPQW------YSGYELGAASLQFE-IAITVE----VREVLHLG----PSVPLASS-----ASRLLSAKL-LGD-LAMYTQLPA-I---------S-------NQ-------VLMVPQPPATNRSAWMLLDKTMLSMDGLACDK------V----G---TGF----SAFRYQP---S---------------------G----C---GRA----PQACLS---------------GQLKDLWEADLARIADG-----------------------------------------RVPLYMITRFTGG------S------DTTLQSFSGGPLS---------FALPVTSH-SQ----------SLVTLSVAAD-GVRLVT----------------------------------------------------N---------------------------------------------------R-SPGKITGAAVCRFAGTS-CGGF-EAVAARGY-IYVNITNTGRLDSDYTLTVSN----CS-SNVRPIEART-----LAVR--AGSAASL-D---PPM-ELYV----EDQ--AAA----AARTC--TVSL------YDSV--------GAVTDSLTLSFYTNATQ-----
1 PsiBlast_PDB 43.5823% -26 - C6 - - 3LX6 - ? A:[89-292] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FIDL----------FAGIGGI--RRGFES-IG-----GQ--CV---FTS-----EWNKHAVRTYKA---NHYCDPA---TH-----HFNEDI----------------------------------------------------------R------------DI-------------T-LSH------------QEGV----------------SDEA--AAE-------HI--R-Q-------HIPE--HD-----VLLAG-FP----------C--------QPF----SLA--------------ACDTQGT---------LFFDVVRIIDAR-----------------RPAM----FVLENVKNLKSHDKGKTFRIIM-QT--LDELGYDVA-D---------A-------EDNGPDDPKIIDGKHFLPQHRERIVLVG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 HHSearch 43.5016% 5 - C6 - - 3QV2 ? A:[8-203] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKQV-----NVIEF----------FSGIGGL--RSSYER-S------SI--NINATFIPF----DINEIANKIYSK---NF---KE---EV------QVKNLDSIS-----------------------------------------I------------K------------QI-------------E--SL------------NCNTWFMSP------PCQPYNNSIMSKHK-------DI--N-D-------PRAK--SV-----LHLYRDIL------PYLIN--------KPK----HIFIENVPLFKESL------------------------------------------------------------------------VFKEIY-NI--LIKNQYYIK-D---------I-------I--------CSPIDIGIPNSRTRYYVMARL----TPFK---------N----E---IQ------LH-----------------------------------QEKESM----ISNYLDN-----N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------