@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKH1: (2017-10-26 )
MHEITLHEVRQLIASLRTVYAAQFNKQFPTSGESAIPLSVVEQIALKTLVGVQQNQFNNALARLLTAGGRFMPSFAEFRTWCIGESWMSPEEAWSRACKFTTDRTVVITQITKYALDEVMYLIEAGQMRAAQDNFFGTYNVMVAKAQLKGRQQEFYTPPLQLEHKEPEHTPVSNDEVQKQLKSLMERLKINGRKPAPVQKLQAKEKEPELAKELGPDPFDNPHEYAEMCRREGMPIPRNILQLIEGANV
Atome Classification :
(20 SA)
---------------------.....-...-.10....-----....20........30........40.....----...-----.50....-....60......-------------..-70---.-------------...-....-----------80....------------...-------------.90--..-----......100..---....--.110...-..------.------.-120---..--......130...-....140.--..---....150.......------------.160.......170..--....--..---------180..-..-..---.190.----......200...-...-----.210.....-...-------220..---..-...230......---.240.......------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------MHEI
T
-
L
H
E
-
V
R
Q
L
I
A
S
-----
L
R
T
V
Y
A
A
Q
F
NKQFPTSGESAI
P
L
S
V
-
V
E
Q
I
A
----
L
K
T
-----
L
VGVQ
Q
N
-
Q
F
N
N
A
L
A
R
L
L
TA-------------GG-RF---M-------------
P
S
F
-
A
E
F
R
-----------
T
W
CIGE------------SWM-------------
S
P
E
--
E
A
-----
W
S
R
ACKFTTD
R
---
T
V
V
I
--
T
Q
I
T
K
Y
A
-
L
D
------
E
------
V
-
M
Y
----
L
I
--EAGQMRAAQDNF-FG
T
Y
N
V
M
V
--
A
K
---AQLKGR-
Q
Q
EFYTP------------PL
Q
L
EHKEPEHTP-VS--
N
D
E
V
--
Q
K
---------
Q
L
K
S
L
-
M
E
-
R
L---KINGR----KPA
P
V
Q
K
L
Q
AKE-KE
P
-----
E
L
A
-
K
ELGP-DPF-------D
N
P
H
E
---
Y
A
-
E
M
C
R
REGMPI
P
R
---
N
I
L
Q
L
IEGANV------------
14
Fugue
63.01
15%
-116
- C4 -
-
2IQC
-
FANCF_HUMAN
A:
[12-210]
---------------------
E
D
S
L
M
-
K
T
Q
-
A
E
L
L
L
E
R
-----
L
Q
E
V
R
P
---------------------
A
R
F
L
----
S
S
L
-----
W
E
R
L
P
Q
N
-
N
F
L
K
V
I
A
V
A
L
L
Q
-------------
P
G
-
S
----------------------
Q
V
L
V
-----------
H
W
L
L
G
N
------------------------------
S
--
E
V
-----
F
A
A
F
C
R
A
---------------------
L
P
------
A
------
G
-
L
L
----
T
L
--
V
T
S
R
H
P
A
L
S
P
V
Y
-
L
G
L
L
T
D
W
G
--
Q
R
---
L
H
Y
D
L
Q
-
K
G
I
W
V
G
T
---------------------
E
S
Q
D
-
V
P
--
W
E
E
L
--
H
N
---------
R
F
Q
S
L
-
C
Q
A
P
P
---
P
L
K
D
K
----
V
L
T
A
L
E
T
C
K
A
Q
D
-
G
D
F
-----
E
V
----------------------------------
P
G
L
S
I
W
T
---
D
L
L
L
A
L
R
S
G
--------------
21
Fugue
58.51
15%
-5
- C4 -
-
5A3A
12
SIRTM_STRPG
A:
[13-302]
---------------------
N
W
T
T
N
-
L
T
Q
-
A
E
Q
L
A
Q
L
-----
I
K
E
A
--------------
D
A
L
V
V
G
I
-
G
A
G
M
S
----
A
A
D
-----
G
F
T
Y
I
G
P
-
R
F
E
T
A
F
P
D
F
I
A
K
-------------
Y
Q
F
L
D
---
M
-------------
L
Q
A
-
S
L
F
D
-----------
F
E
D
W
Q
E
------------
Y
W
A
F
Q
S
R
F
V
A
L
N
YLDQ
P
V
G
--
Q
S
-----
Y
L
D
L
K
E
I
L
E
T
K
D--
Y
H
I
I
--
T
T
N
A
D
N
A
-
F
W
V
A
GYDP
H
------
N
-
I
F
----
H
I
QG
E
Y
G
L
W
Q
C
S
Q
H
C
H
-
Q
Q
T
Y
K
D
D
T
--
V
I
---
R
Q
M
I
A
E
-
Q
K
N
M
K
V
P
GQL
I
P
H
C
PECEA
P
F
E
I
N
K
R
N
E
E
K
G
M
-
V
E
--
D
A
D
F
--
H
A
---------
Q
K
A
R
Y
-
E
A
-
F
L
---
S
E
H
K
E
----
G
K
V
L
Y
L
E
I
G
V
G
H
-
T
T
P
QFI
K
H
P
F
W
-
K
R
V
S
E
-
N
P
N
A
L
F
V
T
LN
H
K
H
Y
R
---
I
P
-
L
S
I
R
R
Q
S
L
E
L
T
E
---
H
I
A
Q
L
I
S
A
T
K
T
I
Y
Q
K--------
23
Fugue
56.66
16%
20
- C3 -
-
5AX7
-
PVG1_SCHPO
A:
[1-348]
KKPLFTKS
P
R
N
S
A
S
C
E
S
T
I
T
L
Q
S
N
L
L
-
F
T
Y
-
Y
K
H
Y
F
A
G
-----
I
K
K
V
A
L
I
G
F
P
D
H
-
P
N
K
G
D
S
A
I
Y
V
A
E
-
K
K
L
L
D
A
L
NI
E
V
V
-----
Y
I
T
A
Q
E
A
-
D
Y
S
A
S
E
L
K
S
I
I
S
DIPRDE
F
A
L
A
F
HG
G
G
-
N
F
GDL
Y
-------------
P
D
H
-
Q
H
L
R
-----------
E
L
V
V
R
D
F
PSFT
T
I
S
F
P
Q
S
V
W
Y
-------------
N
E
Q
--
Q
L
-----
L
E
Q
A
S
I
L
Y
A
E
N
PN
I
T
L
V
T
RD
R
Q
S
Y
G
F
A
-
V
D
------
A
FGKH
N
E
V
-
L
L
T
P
D
I
V
F
--
F
M
G
P
I
P
E
I
R
E
A
T
-
P
I
T
H
D
V
L
I
LA
R
L
---
D
T
L
N
A
A
-
N
L
T
Y
S
V
E
------------
D
W
L
L
W
D
P
P
V
A
Q
N
P
-
D
S
S
F
D
D
R
G
--
Q
A
---------
R
Y
E
A
G
-
A
E
-
F
L
A
SA
R
V
V
I
T
----
D
R
L
H
A
H
I
L
S
T
L
M
-
G
I
P
-----
H
I
V
-
V
E
N
S
Q
M
G
K
I
-------
T
N
Y
H
N
---
T
W
L
H
G
C
T
L
D
G
V
S
V
V
V
---
D
S
V
D
K
A
L
S
L
L
L
E
W
N
E
A
GYF----
2
PsiBlast_PDB
45.07
60%
-219
- C5 -
-
4ZVA
1
DOSC_ECOLI
A:
[51-70]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
--
N
E
Q
V
--
E
R
---------
Q
L
K
S
A
-
M
E
-
R
W
---
I
I
N
------------------------------------------------------------------------------------------------
4
HHSearch
43.14
13%
-174
- C5 -
-
1NO1
-
?
B:
[2-67]
-------------------------
I
-
E
K
D
-
V
V
Q
I
L
K
A
-----
V
S
E
F
Y
P
G
R
F
Q
P
---
D
-
D
L
K
-----
G
-
T
V
K
A
W
----
H
R
V
-----
L
A
E
Y
E
L
E
-
E
I
M
N
N
L
T
D
Y
A
K
--------------
V
N
-
K
F
---
P
-------------
P
T
V
-
S
D
L
L
-----------
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
43.00
11%
-15
- C2 -
-
4WD8
-
?
A:
[25-292]
------------------SK
I
I
F
R
L
L
-
L
N
V
-
L
M
S
I
I
A
I
-----
I
S
Y
Q
W
Y
E
Q
L
G
I
H
L
T
V
A
P
F
S
L
L
G
I
A
I
-
A
I
F
L
G
----
F
R
N
-----
S
A
S
Y
S
R
F
V
E
A
R
N
L
W
G
T
V
L
I
A
-------------
E
R
-
T
L
---
V
-------------
R
Q
L
-
R
N
I
L
PAE
H
D
A
H
R
R
I
V
S
Y
L
V
A
F
------------
S
W
S
-------------
L
K
H
--
Q
L
R
KTDP
T
A
D
L
R
R
L
L
P
E
E
---
R
V
T
E
--
I
L
A
S
S
M
P
-
T
N
------
R
------
I
-
L
L
----
L
A
--
G
N
E
I
G
Q
L
R
E
A
G
K
-
L
S
D
I
T
Y
G
L
--
M
D
---
N
K
L
D
E
L
-
A
H
V
L
G
G
C
------------
E
R
L
A
T
T
P
V
P
F
A
Y
T
-
L
I
--
L
Q
R
T
--
V
Y
---------
L
F
C
T
L
-
L
P
-
F
A
---
L
V
G
D
L
HYM
T
P
F
V
S
V
F
I
S
Y
T
F
L
-
S
W
D
-----
S
L
A
-
E
E
L
-
E
-
D
P
F
-------
G
T
A
A
N
---
D
L
-
P
-
L
N
A
M
C
N
T
I
E
R
---
N
L
L
D
M
T
G
Q
---------------
3
PsiBlast_PDB
42.98
60%
-219
- C5 -
-
4ZVB
1
DOSC_ECOLI
A:
[56-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
--
N
E
Q
V
--
E
R
---------
Q
L
K
S
A
-
M
E
-
R
W
---
I
I
N
------------------------------------------------------------------------------------------------
22
Fugue
41.12
21%
-40
* C4 *
-
2KPO
-
?
A:
[1-110]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
L
Y
V
L
I
-
I
S
------
N
------
D
-
K
K
----
L
I
--
E
E
A
R
K
M
A
E
K
A
N
L
---
E
L
R
T
V
K
--
T
E
---
D
E
L
K
K
Y
-
L
E
E
F
R
K
E
------------
S
----
Q
N
I
K
V
L
I
L
-
V
S
--
N
D
E
E
--
L
D
---------
K
A
K
E
L
-
A
Q
-
K
M
---
E
I
D
V
R
----
T
R
K
V
T
S
P
D
E
A
K
R
-
W
I
K
-----
E
F
S
-
E
E
G
G
S
-
L
E
H
-------
H
H
H
H
H
--------------------------------------------
9
HHSearch
40.60
25%
-304
- C5 -
-
4P78
1
?
B:
[40-59]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
A
V
---
H
I
-
E
A
L
M
N
E
G
F
P
L
P
S
---
P
----------------------
20
Fugue
40.49
11%
29
- C4 -
-
5KLP
3
?
A:
[18-342]
----------TQS
M
R
L
Q
Q
K
I
N
D
L
K
P
Y
-
V
R
H
-
A
R
G
P
I
K
A
-----
Y
G
Q
A
A
L
D
R
A
S
G
A
V
S
F
A
E
L
D
A
T
H
L
D
A
M
V
Y
I
E
N
----
Q
R
N
PGLN
L
K
H
F
R
D
H
Y
-
Y
L
I
Q
A
L
Q
S
D
G
P
S
-------------
A
F
-
R
A
---
I
F
P
Q
T
C
PETGQTLK
H
H
V
M
A
D
V
R
-----------
L
H
Q
G
A
P
------------
T
I
I
-------------
I
T
E
PA
V
I
-----
V
G
A
R
Y
Q
Q
L
Q
R
H
---
N
L
T
L
--
E
D
L
S
E
S
G
-
V
P
------
L
------
S
Q
V
A
----
I
I
--
E
T
Q
A
A
A
T
S
D
D
C
V
M
Y
S
L
N
Y
A
I
K
--
A
H
K
N
A
A
Q
F
D
D
I
-
H
H
G
L
Q
H
G
------------
T
L
S
T
E
S
E
S
R
A
R
T
T
-
L
G
--
A
L
E
A
--
S
S
SYSVMHEG
A
H
A
A
F
G
-
A
D
-
V
L
---
P
V
D
F
Y
----
K
H
G
A
S
L
T
Q
A
Y
Y
L
M
K
R
P
-----
D
G
R
M
A
G
R
V
N
-
S
E
G
-------
H
S
E
A
E
---
N
L
-
V
Q
-
R
N
Q
A
F
R
V
K
T
---
Q
F
S
A
S
I
D
G
F
R
L
Q
E
I
K
R
V
L
A
A
A
Q
R
18
Fugue
39.30
15%
34
- C4 -
-
1EFP
2
ETFB_PARDE
B:
[1-246]
---------------M
K
V
L
V
P
V
K
R
L
I
-
D
Y
N
-
V
K
A
R
V
K
S
DGSGV
D
L
A
N
V
K
M
S
M
N
P
F
D
E
I
A
V
E
E
A
I
R
L
K
E
-
K
G
Q
A
E
----
E
I
I
-----
A
V
S
I
G
V
K
-
Q
A
A
E
T
L
R
T
A
L
A
M
-------------
G
A
-
D
-------------------
R
A
-
I
L
V
V
-----------
A
A
D
D
V
Q
------------
Q
D
I
-------------
E
P
L
--
A
V
-----
A
K
I
L
A
A
V
A
R
A
E
---
G
T
E
L
--
I
I
A
G
K
Q
A
-
I
D
------
N
------
D
-
M
N
--------
A
T
G
Q
M
L
A
A
I
L
G
W
-
A
Q
A
T
F
A
S
K
--
V
E
---
I
E
G
A
K
A
-
K
V
T
R
E
V
D
------------
G
G
L
Q
T
I
A
V
S
L
P
A
V
-
V
T
--
A
D
L
R
L
N
E
P
---------
R
Y
A
S
L
-
P
N
-
I
M
---
K
A
-------
K
K
K
P
L
D
E
K
T
A
A
D
-
Y
G
V
-----
D
V
A
-
P
R
L
E
V
-
V
S
V
-------
R
E
P
E
G
---
R
K
-
A
G
I
K
V
G
--
S
V
D
E
---
L
V
G
K
L
------------------
10
HHSearch
37.05
20%
-73
- C5 -
-
1GWU
1
PER1A_ARMRU
A:
[138-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
P
-
G
P
F
-------
F
T
L
P
Q
---
L
K
-
D
S
F
R
N
V
G
L
N
R
S
S
---
D
L
V
A
L
S
G
G
H
T
-------------
15
Fugue
35.53
13%
15
- C4 -
-
2P7I
2
?
A:
[23-247]
--------------------N
F
D
F
D
V
M
H
P
F
M
V
R
A
F
T
P
F
-----
F
R
P
G
N
L
L
E
L
G
---
S
F
K
G
D
F
T
S
R
L
Q
E
-
H
F
N
--------
D
-----
I
T
C
V
E
A
S
-
E
E
A
I
S
H
A
Q
G
R
L
K
-------------
D
G
-------------------------------------------
I
T
------------
Y
I
H
-------------
S
R
F
--
E
D
-----
A
Q
L
P
R
R
Y
--
D
N
---
I
V
L
T
--
H
V
L
E
H
I
D
D
P
V
------
A
------
L
-
L
K
----
R
I
--
N
D
D
W
L
A
E
G
G
R
L
F
-
L
V
C
P
N
A
N
A
--
V
S
---
R
Q
I
A
V
K
M
G
I
I
S
H
N
S
------------
A
V
T
E
A
E
F
A
H
G
H
R
C
T
Y
A
--
L
D
T
L
--
E
R
---------
D
A
S
R
A
G
L
Q
-
V
T
---
Y
R
S
G
I
----
F
F
K
A
L
A
N
F
Q
W
D
Q
-
I
L
Q
-----
T
D
------------------
I
L
S
K
E
---
Y
L
-
D
G
C
Y
Q
L
G
Q
Q
Y
P
D
LCA
S
I
F
L
L
C
E
K
G
--------------
7
HHSearch
33.44
20%
-58
- C5 -
-
1ATJ
1
PER1A_ARMRU
E:
[137-171]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
P
-
A
P
F
-------
F
T
L
P
Q
---
L
K
-
D
S
F
R
N
V
G
L
N
R
S
S
---
D
L
V
A
L
S
G
G
H
T
-------------
11
HHSearch
32.45
15%
-146
- C5 -
-
1QEY
-
RMNT_BPP22
A:
[61-80]
-----------------------
E
Q
S
-
E
L
V
-
K
K
M
V
F
D
T
-----
L
K
D
L
Y
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
30.92
25%
-248
- C5 -
-
4P7D
-
?
B:
[40-59]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
A
V
---
H
I
-
E
A
L
M
N
E
G
F
P
L
P
S
---
P
----------------------
5
HHSearch
29.56
10%
-169
- C5 -
-
2DSY
-
?
A:
[55-74]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
L
E
D
---
W
L
-
L
F
L
L
S
R
G
E
T
P
P
P
---
L
----------------------
6
HHSearch
25.26
10%
-131
* C5 *
-
2DSY
-
?
D:
[55-74]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
L
E
D
---
W
L
-
L
F
L
L
S
R
G
E
T
P
P
P
---
L
----------------------
1
PsiBlast_PDB
22.71
32%
-
- C5 -
-
4PH6
-
AROD_ENTFA
A:
[86-131]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
G
E
M
A
F
S
E
E
N
Y
-
F
A
L
Y
H
E
L
V
--
K
K
---
G
A
L
D
L
L
-
D
I
E
L
F
A
N
------------
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
22.63
34%
5
- C1 -
-
2MSQ
-
?
A:
[1-27]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
C
G
G
-
S
C
F
-------
G
G
C
W
G
C
S
C
Y
A
-
R
T
C
F
R
D
G
L
P
-----------------------------