@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKI2: (2017-10-26 )
MPIDTQLTTLFCLIDDFCTDITQNVEQYMLTYGQTKRLRQSKIHASEVITLLLWFHLTGSRNFKAFYLYWAKPFLCSYFTNLPSYSRFIELKAKYAMYFVALIESLKVHSAGIAFIDSTKLAVCHNKRIHQHRVFADSASRGKTSVDWFYGFKIHLICDHIGRLVSYCITTGNVDDRKVLPDLIEHSKLKGKLFGDRGYVGKNWKSRLAEVGVQLITRVKRNMKPQVLAPFDHAVLKKRGIIEALFKLMKSQFDLEHSRHRSKMGLLTTIFAALTLYALVLVNGYKSGIQQILKPIDLNSA
Atome Classification :
(14 SA)
---------------------------------------------...-----......10-------------------.....--...20.---------------...-------....30---.......-.40........50..---------.....-.60.---.--------------------......-----70...----------..-------------------...80........90.......------.100.......110--....--.--...120----.....--....130.......140.......150.......160.......170....-..---------------.180...------....190.-..-....200...---------------------------....210.......220..--..--...230---.........240.......250-----....---....-260....-..-------.270----------.....-.-..280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------MPI-----DTQ
L
T
T
L
F
-------------------
C
L
I
D
D
--
F
C
T
D
I
T
---------------
Q
N
V
-------
E
Q
Y
M
L
T
---YG
Q
T
K
R
L
-
R
Q
SKI
H
A
S
E
V
I
T
L
L
L
---------
W
F
HLT-GSR
N
---
F
--------------------
K
A
F
Y
L
Y
-----WA
K
P
F
----------
L
C
-------------------
S
Y
F
TNLP
S
Y
S
R
F
I
E
L
K
A
K
Y
A
M
Y
------
F
V
A
L
I
E
S
L
KVHSA---
G
I
A
F
--I--DS
T
K
------
L
A
V
C
H--NKRI
H
Q
H
R
VFADSASRGK
T
S
V
D
W
F
Y
G
F
K
I
H
L
I
C
D
H
I
G
R
L
V
S
Y
C
ITTGNVD
D
-
R
K
---------------
V
L
P
D
L
I
E
------
H
S
KLK
G
K
L
-FG-DRGYVG
K
N
W
K
---------------------------
S
R
L
A
E
V
G
V
Q
L
I
T
R
V
K
RNMK--P
Q
--
V
LAP-----F
D
H
A
V
L
K
KR
G
I
I
E
A
L
F
K
L
M
K
S
------QFD
L
---
E
H
S
R
-
H
R
S
KM
G
L
-
L
T
-------
T
I
F
-----------
A
A
L
T
L
-
Y
-
A
L
V
L
V
N
G
Y
K
S
G
I
Q
Q
I
L
K
PIDLNSA-
16
Fugue
78.23
16%
-
- C4 -
-
4N74
-
?
A:
[264-577]
---------------------TQ
N
T
I
E
T
G
V
G
Y
S
TDV
G
P
R
V
K
A
T
W
K
K
P
W
VNSYG
H
S
L
T
T
S
T
S
-------------------
I
S
A
P
E
--
Q
T
L
D
F
S
---------------
Y
K
M
P
L
LKNPL
E
Q
Y
Y
L
V
---
Q
G
G
F
K
R
T
-
D
L
N
D
T
E
S
D
S
T
T
L
V
A
S
---------
R
Y
W
D
L
-
S
S
G
W
---
Q
--------------------
R
A
I
N
L
R
-----
W
S
V
D
H
----------
F
T
-------------------
Q
G
-----------
E
I
T
N
T
T
M
L
F
------
Y
P
G
V
V
I
S
R
T
R
S
R
G
---
G
L
M
P
--
T
W
G
D
S
Q
R
------
Y
S
I
D
Y
--
S
N
T
A
W
G
S
D
V
D
F
S
V
F
Q
A
Q
N
V
W
I
R
T
L
Y
D
R
H
R
F
V
T
R
G
T
L
G
W
I
E
T
-------
G
D
F
-
D
K
---------------
V
P
P
D
L
R
F
------
F
A
G
G
D
R
S
I
-
R
G
Y
K
Y
K
S
I
A
P
K
Y
A
---------------------------
N
G
D
L
K
G
A
S
K
L
I
T
G
S
L
E
Y
Q
Y
--
N
V
--
T
-
G
K
-----
W
W
G
A
V
F
V
D
S
G
--
E
A
V
S
D
I
R
R
S
------
D
F
K
T
G
T
G
V
G
V
R
-
W
E
S
P
V
G
P
-
I
K
-------
L
D
F
-----------
A
V
P
V
A
--------
D
K
D
E
H
G
L
Q
F
Y
I
G
L
G
P
E
L
---
14
Fugue
58.15
15%
-17
- C6 -
-
5HC3
-
?
A:
[22-365]
MTNKIAEDPRID
P
R
I
K
A
I
FSGMDL
G
G
G
G
D
V
ES
R
E
A
M
L
E
A
A
S
S
E
E
A
T
A
V
-----
R
D
G
L
R
V
F
L
-------------------
D
A
C
D
N
EE
I
A
P
S
A
G
---------------
L
K
I
-------
E
D
Y
E
F
T
S
E
P
D
G
N
I
A
K
I
-
Q
Y
I
R
P
D
S
T
D
K
L
P
C
V
Y
---------
Y
I
H
G
G
-
G
M
Q
S
LSC
Y
--------------------
Y
G
N
Y
R
A
-----
W
G
K
I
I
A
S
N
G
V
A
V
---
A
M
-------------------
V
E
F
R
N
A
L
V
P
S
A
L
P
E
V
-
A
P
Y
P
A
G
------
L
N
D
C
V
S
G
V
K
W
V
A
A
---
H
A
D
E
LG
I
--
D
A
S
R
------
I
I
I
A
G
--
E
S
G
G
G
N
L
T
L
A
A
G
L
R
L
K
Q
E
G
S
Q
D
L
I
Q
G
--
L
Y
A
L
C
P
Y
I
A
G
S
W
P
S
E
D
S
P
S
S
T
E
N
-
N
G
---------------
I
L
L
D
L
--------
H
N
N
Q
G
A
M
G
-
Y
G
-
I
E
A
Y
E
M
R
D
P
L
---------------------------
A
W
P
G
F
A
T
E
E
D
V
S
----
G
L
V
--
P
T
--
F
I
S
V
-----
N
E
C
D
P
L
R
D
E
G
I
-
N
F
Y
R
L
L
L
R
A
------
G
V
S
------
A
K
-
C
R
Q
V
M
G
-----------
T
I
H
-----------
G
-
T
E
I
-
F
-
P
I
A
C
P
D
V
S
R
D
T
A
A
S
I
A
N
F
C
K
G
G
---
20
Fugue
55.90
19%
-17
- C5 -
-
4USR
2
?
A:
[1-357]
---------------------GPAMPPILD
V
I
V
I
G
GG
Q
A
A
L
T
T
A
Y
F
L
R
-----
R
T
S
L
S
Y
L
L
L
D
EQPGPGGAWLHAWDSLR
L
F
S
P
A
--
A
W
S
S
I
A
GWPMPSPTEPGNPT
R
N
D
V
-------
I
D
Y
L
R
R
---
Y
E
D
R
Y
Q
F
P
I
Q
R
P
V
R
V
D
T
V
T
R
L
D
D
---------
L
W
R
V
Q
A
G
D
Q
Q
---
W
--------------------
L
A
R
A
V
I
S
ATGT
W
S
K
P
F
----------
I
--------------------------
P
P
Y
E
G
------------------
R
E
L
F
Q
G
A
Q
I
H
S
A
HYR
T
P
A
P
--
F
--
A
G
K
R
------
V
M
V
V
G
--
G
G
N
-
S
G
A
Q
V
L
A
E
L
S
S
V
--
S
E
T
L
W
I
T
Q
E
P
P
A
F
L
P
D
E
V
D
G
R
V
L
F
E
R
A
T
A
R
W
K
A
-
Q
Q
EGRSIDEPAGGFGDI
V
M
V
P
P
V
R
------
E
A
R
E
R
G
V
L
-
V
A
-
E
R
P
F
---------------------------------
A
R
F
T
E
T
G
V
E
W
A
D
G
R
R
E
N
L
D
--
A
V
--
I
W
C
S
GFRPA
L
D
H
L
--
R
E
L
G
V
V
E
A
D
G
K
V
Q
V
E
------
D
T
R
V
---
V
K
Q
P
-
N
L
W
L
V
G
Y
G
D
W
-------
T
G
M
-----------
A
S
A
T
L
-
I
-
G
V
T
R
T
--
A
R
S
T
A
D
Q
V
V
Q
A
L
T
A
T
P
--
12
Fugue
41.65
13%
-115
* C6 *
-
1BIF
1
?
?:
[38-250]
--------------------------------------------------------
C
P
T
L
I
-------------------
V
M
V
G
L
--
P
A
R
--------------------------------------
G
K
T
Y
I
S
-
K
K
L
T
R
Y
L
N
F
I
G
V
P
T
R
---------
E
F
N
V
G
-
Q
Y
R
R
---
D
--------------------
M
V
-----------
K
T
Y
----------
K
S
-------------------
F
E
F
F
L
P
D
N
E
E
G
L
K
I
R
K
Q
C
A
L
A
A
------
L
N
D
V
R
K
F
L
S
E
E
G
G
---
H
V
A
V
--
F
--
D
A
T
-----------
N
--
T
T
R
E
R
R
A
M
I
F
N
F
G
E
Q
N
G
----------------------
Y
K
T
F
F
V
E
S
I
C
V
D
-
P
E
---------------
V
I
A
A
N
I
V
------
Q
V
K
L
G
S
P
D
-
Y
V
-
N
R
D
----------------------------------------------------
S
--
D
E
--
A
T
E
D
-----
F
M
R
R
I
E
C
Y
E
N
S
Y
E
S
L
--------------------
D
E
E
-
Q
D
R
D
L
S
Y
-
I
K
-------
I
M
D
-----------
V
G
Q
S
Y
-
V
-
V
N
R
V
A
D
H
I
Q
S
R
I
V
Y
Y
L
M
N
I
H
V
T
P
R
-
18
Fugue
40.93
19%
-19
- C3 -
-
4UX8
-
RET_HUMAN
A:
[1-480]
------------------------------LYFSRD
A
Y
W
E
K
L
Y
V
D
Q
A
A
-----
G
T
P
L
L
Y
V
H
-------------------
A
L
R
D
A
--
P
E
E
V
P
S
---------------
F
R
L
-------
G
Q
H
L
Y
G
---
T
Y
R
T
R
L
H
-
E
N
N
W
I
R
I
Q
E
D
T
G
L
L
Y
L
Q
R
S
L
D
H
S
S
W
E
K
L
S
V
R
N
R
G
---
F
PLL
T
V
Y
L
K
V
F
LSPCQWPG
C
A
R
V
Y
F
S
F
-----
F
N
T
S
F
PACSSLK
P
R
E
L
C
FPE
T
R
P
S
F
R
I
R
E
NRPPGTF
H
Q
F
R
L
L
P
V
Q
F
L
C
P
Q
I
S
V
A
Y
R
L
L
EGEGLP
F
R
S
A
P
D
S
L
E
V
S
T
R
---
W
A
----
L
--
D
R
E
Q
RE
K
Y
E
L
V
A
V
C
T
V
H
R
E
E
V
V
M
V
P
F
P
V
T
V
Y
D
E
D
D
S
A
P
T
F
P
A
G
V
D
T
A
S
A
V
V
E
F
K
R
K
E
D
T
V
V
A
T
L
R
V
F
D
-
A
D
---------------
V
V
P
A
S
G
E
LV
R
R
Y
T
S
T
L
L
P
G
D
T
-
W
A
-
Q
Q
T
F
R
V
E
H
W
P
NET
S
V
Q
A
N
G
S
F
V
RAT
V
H
D
Y
R
L
V
LNRNL
S
I
S
E
N
R
T
M
Q
L
A
V
L
V
N
D
S
L
H
LP
S
T
--
Y
S
L
S
-----
V
S
R
R
A
R
R
F
A
Q
I
G
K
V
C
V
E
N
C
Q
A
FSGIN
V
Q
Y
K
L
---
H
S
S
G
A
N
C
S
T
L
G
V
-
V
T
SAEDTSG
I
L
F
V
N
DTKALRRPK
C
A
E
L
H
-
Y
-
M
V
V
A
T
D
Q
Q
T
S
R
Q
A
Q
A
Q
L
L
V
T
V
E
G
S
Y
11
Fugue
37.08
17%
-72
- C2 -
-
5LSJ
-
PMF1_HUMAN
B:
[2-174]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
R
V
K
L
L
D
T
---
M
V
D
T
--
F
--
L
Q
K
L
------
V
A
A
G
S
--
Y
Q
R
F
T
D
C
--
Y
K
C
F
Y
Q
L
Q
P
A
M
T
Q
Q
I
Y
D
K
F
I
A
Q
L
Q
T
S
I
R
E
E
I
S
D
I
K
E
E
G
N
L
E
A
V
L
N
---------------
A
L
D
K
I
V
E
------
E
G
K
V
R
K
E
P
A
W
R
-
P
S
G
I
P
E
K
D
L
H
---------------------------
S
V
M
A
P
Y
F
L
Q
Q
R
D
T
L
R
R
H
V
Q
--
K
Q
E
A
E
N
Q
Q
-----
L
A
D
A
V
L
A
G
R
R
Q
V
E
E
L
Q
L
Q
V
Q
A
------
Q
Q
Q
A
---
W
Q
A
L
-
H
R
E
Q
R
E
L
-
V
A
-------
V
L
R
-----------
E
--------------------------------
6
HHSearch
35.03
17%
-409
- C7 -
-
3PCQ
-
PSAM_THEEB
M:
[3-20]
-------------------------------------------------------------------------------------------------------------------------------------------
L
T
D
T
Q
V
Y
V
A
L
V
---------
I
A
L
L
P
-
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
34.27
9%
-171
* C7 *
-
4HLB
-
?
A:
[34-88]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
-
Y
A
-
D
K
G
I
R
S
V
D
V
A
---------------------------
A
Y
A
K
G
I
D
I
V
F
V
A
A
D
R
K
M
T
R
--
A
E
--
F
----------------
S
A
I
A
S
R
S
I
R
E
L
K
E
------
R
F
G
F
---
D
K
-------------------------------------------------------------------
10
HHSearch
30.02
13%
-259
- C1 -
-
1OGD
1
RBSD_BACSU
B:
[21-36]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
K
I
V
-
I
A
-
D
A
G
L
P
V
P
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
12.59
18%
0
- C- -
-
4DM0
-
TN5P_ECOLX
A:
[317-381]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
Y
T
H
R
W
R
I
E
E
F
H
K
A
W
K
T
------
G
A
G
A
---
E
R
Q
R
-
M
E
K
P
D
N
L
-
E
R
-------
M
V
S
-----------
I
L
S
F
V
A
V
-
R
L
L
Q
L
--------------------
1
HHSearch
12.59
18%
0
- C- -
-
1MUS
1
TN5P_ECOLX
A:
[317-382]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
Y
T
H
R
W
R
I
E
E
F
H
K
A
W
K
T
------
G
A
G
A
---
E
R
Q
R
-
M
E
K
P
D
N
L
-
E
R
-------
M
V
S
-----------
I
L
S
F
V
-
A
V
R
L
L
Q
L
--------------------
13
Fugue
10.96
29%
0
- C- -
-
1VF5
-
PETL_MASLA
E:
[1-32]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
------
Y
I
V
F
I
A
L
F
F
G
I
A
V
---
G
I
I
F
A
-
I
--
K
S
I
K
------
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
7.00
11%
-153
- C7 -
-
4KT0
-
PSAM_SYNY3
M:
[3-20]
-------------------------------------------------------------------------------------------------------------------------------------------
L
S
D
T
Q
I
L
A
A
L
V
---------
V
A
L
L
P
-
A
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
0.98
17%
0
- C- -
-
1JB0
-
PSAM_THEEB
M:
[3-20]
-------------------------------------------------------------------------------------------------------------------------------------------
L
T
D
T
Q
V
Y
V
A
L
V
---------
I
A
L
L
P
-
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------