@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKI6: (2017-10-26 )
MQDDISGWTEWNAHFEGIEEISSPSELHGLLTGIVCVTEAPTLEEWTQILTTLNVPELNEEALALLTDEAEDVAHALSEDELDYLPMLPDDEHLLQDRVQALSDWCAGVVLGFGLASGHVRTDERELIEHLQDVAAVEFEDSDNDEEGESSYEELYEFVRLIPVSLSIGRKKVTVAESSLLKNFYAKSKTSTVGTADQNIVEMFTPHRPS
Atome Classification :
(20 SA)
--------------------------------------------------.........10-....-------------------....20........30..---------.-.-...-.----40.......-.50.-.--...---------.-..60....-....70........-80-........90...-------.....100.....-.----.110....--..--.120---.----.....---..130--....------------------...----.-------------.140---------.........150.......160-------.-......170.......180.-------......190.......200.......210--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------MQDDISGWTE
W
-
N
A
H
F
-------------------
E
G
I
E
EIS
S
P
S
E
L
H
G
L
L
T
G
---------
I
-
V
-CVT-E----AP
T
L
E
E
W
T
Q
-
I
L
T
T-L--NVP---------E-L
N
E
E
A
L
A
L
-LTD
E
A
E
D
V
A
H
A
LSE-DE-LDYLPMLPD
D
E
H
L
-------
L
Q
D
R
V
Q
A
L
S
D
W
C
A
-
G
----
V
V
L
G
F
GLA--SG--HVR----T----
D
E
R
E
L
---
I
E
H
----
L
Q
D
V
------------------
A
A
V
----E-------------FE-----------DSDNDEEG
E
S
S
Y
E
E
L
Y
E
F
V
R
L
I-------P-
V
S
L
SIG
R
K
K
V
T
V
A
E
S
S
L
L
K
N
-------
F
Y
AKSKTSTVGTA
D
Q
N
I
V
E
M
FTPHRPS----
18
Fugue
87.28
21%
-79
- C2 -
-
4GYT
-
?
A:
[8-184]
---------------------------------------------------
S
L
H
L
P
K
Y
D
D
F
-
V
Q
S
I
-------------------
S
V
L
A
L
T
M
S
G
S
E
L
H
G
I
M
C
G
---------
Y
-
L
-
C
A
G
-
A
----
D
S
Q
G
E
A
Y
I
R
-
A
L
L
N
-
N
--
K
K
D
---------
E
-
Q
S
R
N
A
L
L
S
-
M
F
S
V
F
S
I
S
Q
Q
Q
M
N
N
-
F
D
-
F
E
F
E
M
L
L
P
D
D
D
E
S
-------
L
V
T
R
A
Q
A
F
S
E
W
C
E
-
G
----
F
T
Q
G
L
T
I
A
--
G
V
--
G
M
E
QFYE
E
----
E
S
Q
D
A
---
L
Q
H
----
L
M
E
F
------------------
A
E
L
----
D
-------------
C
E
-----------
S
L
E
V
G
E
E
D
E
R
A
L
M
E
V
S
E
Y
T
R
M
A
-------
V
-
L
R
L
H
S
D
L
V
L
H
E
-----------------------------------------------
28
HHSearch
82.87
22%
-33
- C2 -
-
4GYT
-
?
B:
[9-183]
----------------------------------------------------
L
H
L
P
K
Y
D
D
F
-
V
Q
S
I
-------------------
S
V
L
A
L
T
M
S
G
S
E
L
H
G
I
M
C
G
---------
Y
-
L
-
C
A
G
-
A
----
D
S
Q
G
E
A
Y
I
R
A
L
L
N
N
-
K
--
K
D
E
---------
Q
--
S
R
N
A
L
L
S
-
M
F
S
V
F
S
I
S
Q
Q
Q
M
N
N
-
F
D
-
F
E
F
E
M
L
L
P
D
D
D
E
S
-------
L
V
T
R
A
Q
A
F
S
E
W
C
E
-
G
----
F
T
Q
G
L
T
I
A
GV
G
M
EQ
F
Y
E
----
E
----
E
S
Q
D
A
---
L
Q
H
----
L
M
E
F
------------------
A
E
L
----
D
-------------
C
E
-----------
S
L
E
V
G
E
E
D
E
R
A
L
M
E
V
S
E
Y
T
R
M
A
-------
V
-
L
R
L
H
S
D
L
V
L
H
------------------------------------------------
19
Fugue
82.04
23%
32
- C2 -
-
1IZM
-
Y817_HAEIN
A:
[2-171]
-------------------------------------------------------
L
I
S
H
S
D
M
N
Q
Q
L
-------------------
K
S
A
G
I
G
F
N
A
T
E
L
H
G
F
L
S
G
---------
L
-
L
-
C
G
-------
G
L
K
D
Q
S
W
L
P
-
L
L
Y
Q
-
F
SN
D
N
H
---------
A
-
Y
P
T
G
L
V
Q
P
-
V
T
E
L
Y
E
Q
I
S
Q
T
L
S
D
-
V
E
-
G
F
T
F
E
L
G
L
T
E
D
E
N
-------
V
F
T
Q
A
D
S
L
S
D
W
A
N
-
Q
----
F
L
L
G
I
G
L
A
--
Q
P
--
E
L
A
----
K
EKG-
E
I
G
E
A
---
V
D
D
----
L
Q
D
I
------------------
C
Q
L
----
G
-------------
Y
D
-----------
E
D
D
N
E
E
E
L
A
E
A
L
E
E
I
I
E
Y
V
R
T
I
-------
A
M
L
---------------
F
Y
S
H
-------
F
N
-----------------------------
1
PsiBlast_PDB
79.04
25%
-80
- C2 -
-
4GYT
-
?
A:
[29-176]
--------------------------------------------------------------------------------------------
S
G
S
E
L
H
G
I
M
C
G
---------
Y
-
L
-
C
A
G
-
A
----
D
S
Q
G
E
A
Y
I
R
-
A
L
L
N
-
N
--
K
K
D
---------
E
-
Q
S
R
N
A
L
L
S
-
M
F
S
V
F
S
I
S
Q
Q
Q
M
N
N
-
F
D
-
F
E
F
E
M
L
L
P
D
D
D
E
S
-------
L
V
T
R
A
Q
A
F
S
E
W
C
E
-
G
----
F
T
Q
G
L
T
I
A
--
G
V
--
G
M
E
----
Q
FYE
E
E
S
Q
D
A
---
L
Q
H
----
L
M
E
F
------------------
A
E
L
----
D
-------------
C
E
-----------
S
L
E
V
G
E
E
D
E
R
A
L
M
E
V
S
E
Y
T
R
M
A
-------
V
-
L
R
L
-------------------------------------------------------
29
HHSearch
78.63
23%
29
- C2 -
-
1IZM
-
Y817_HAEIN
A:
[2-171]
------------------------------------------------------
L
I
S
H
S
D
M
-
N
Q
Q
L
-------------------
K
S
A
G
I
G
F
N
A
T
E
L
H
G
F
L
S
G
---------
L
-
L
-
C
G
G
-
L
----
K
D
--
Q
S
W
L
P
L
L
Y
Q
F
-
S
--
N
D
N
---------
H
A
Y
P
T
G
L
V
Q
P
-
V
T
E
L
Y
E
Q
I
S
Q
T
L
S
D
V
E
G
-
F
T
F
E
L
G
L
T
E
D
E
-
N
-------
V
F
T
Q
A
D
S
L
S
D
W
A
N
-
Q
----
F
L
L
G
I
G
L
A
Q
P
E
L
A-
K
E
K
----
G
----
E
I
G
E
A
---
V
D
D
----
L
Q
D
I
------------------
C
Q
L
----
G
-------------
Y
D
-----------
E
D
D
N
E
E
E
L
A
E
A
L
E
E
I
I
E
Y
V
R
T
I
-------
A
-
M
L
F
Y
S
H
F
N
--------------------------------------------------
2
PsiBlast_PDB
75.42
28%
49
- C2 -
-
1IZM
-
Y817_HAEIN
A:
[20-162]
--------------------------------------------------------------------------------------------
N
A
T
E
L
H
G
F
L
S
G
---------
L
-
L
-
C
---
G
----
G
L
K
D
Q
S
W
L
P
-
L
L
Y
Q
-
F
S-
N
D
N
---------
H
-
A
Y
P
T
G
L
V
Q
P
V
T
E
L
Y
E
Q
I
S
Q
T
L
S
D
-
V
E
G
F
T
F
E
L
G
L
T
E
D
E
N
V
-------
F
T
-
Q
A
D
S
L
S
D
W
A
N
-
Q
----
F
L
L
G
I
G
L
A
--
Q
P
--
E
L
A
----
K
----
E
K
G
E
I
G
E
A
V
D
D
----
L
Q
D
I
------------------
C
Q
L
----
G
-------------
Y
D
-----------
E
D
D
N
E
E
E
L
A
E
A
L
E
E
I
I
E
Y
V
R
T
I
-------------------------------------------------------------------
22
Fugue
63.05
22%
38
- C2 -
-
5B46
2
?
B:
[4-304]
RKPVFVDWCPGCG
D
F
G
I
L
R
A
E
E
M
A
I
R
E
L
GINPKS
V
V
I
V
S
G
I
G
CSGKIPHF
M
N
L
P
I
S
G
V
H
---
T
L
H
G
-------------------
R
S
I
A
F
A
T
G
I
K
L
S
N
P
S
L
E
V
---------
I
-
V
-
N
V
G
-
D
----
G
D
G
L
G
I
G
M
G
-
H
F
V
H
-
L
--
G
R
R
---------
N
-
I
D
---
I
A
V
-
L
V
H
N
N
G
--
V
Y
G
L
T
K
-
G
Q
-
A
S
--
P
T
L
H
R
G
E
K
T
KSLPKPN
I
M
D
A
V
N
P
L
A
V
A
L
A
-
A
GYT
F
V
A
R
G
Y
A
Y
D
--
V
M
--
H
L
K
----
E
----
L
I
K
K
A
---
I
L
H
K
G
S
A
L
V
D
I
LQPCPTYNDINT
K
E
W
Y
D
K
R
V
Y
----
K
-------------
L
D
NVPGWDPVVRK
E
E
E
A
Q
K
K
F
E
Q
A
I
M
K
S
Y
E
W
G
E
K
I
-------
P
-
I
G
I
F
Y
Q
N
E
L
V
P
T
F
E
D
R
L
T
S
N
I
P
NYREY
Y
P
A
K
Q
Q
I
E
I
N
G
I
S
T
T
K
I
D
E
L
I
K
A
K
R
I
-----
14
PsiBlast_PDB
54.67
24%
19
- C2 -
-
3PJR
1
?
A:
[468-558]
--------------------------------------------------------------------------------------------------------------------------------
L
E
Q
W
T
Q
-
L
Q
E
Y
-
V
--
S
V
T
---------
E
-
L
V
E
E
V
L
------------------
D
K
-
S
G
Y
R
E
M
L
K
A
E
R
T
I
E------
A
Q
S
R
L
E
N
L
D
E
F
L
S
-------------
V
--
T
K
--
H
F
E
N
V--
S
----
D
D
K
S
L
---
I
A
F
----
L
T
D
L
------------------
A
L
I
SDLD
E
---------------------------
T
E
Q
A
A
E
G
D
A
-------------------------------------------------------------------------------
15
PsiBlast_PDB
50.90
27%
14
- C2 -
-
2PJR
1
?
A:
[468-546]
--------------------------------------------------------------------------------------------------------------------------------
L
E
Q
W
T
Q
-
L
Q
E
Y
-
V
--
S
V
T
---------
E
-
L
V
E
E
V
L
------------------
D
K
-
S
G
Y
R
E
M
L
K
A
E
R
T
I
E
------
A
Q
S
R
L
E
N
L
D
E
F
L
S
-------------
V
--
T
K
--
H
F
E
N
V--
S
----
D
D
K
S
L
---
I
A
F
----
L
T
D
L
------------------
A
L
I
--------------------------------
S
D
L
D
E
-----------------------------------------------------------------------------------
9
PsiBlast_PDB
50.29
31%
-89
- C3 -
-
5FBJ
2
A:
[48-108]
-----------------------------------------------------------------------------------------------
E
I
A
G
C
R
T
V
---------
P
-
V
-
E
V
G
-
S
----
R
Y
T
D
E
E
W
S
Q
-
T
L
M
T
------------------
V
N
E
F
I
S
K
Y
-
I
V
N
E
P
R
D
V
G
Y
L
A
Q
H
-
Q
L
-
F
D
Q
I
P
E
L
K
Q
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
50.20
14%
-28
- C2 -
-
2LXM
-
VTA1_HUMAN
A:
[1-163]
------------------------------------------------------------------------------------------
M
A
A
L
A
P
L
P
P
L
-------------------------
P
A
Q
F
K
S
I
Q
H
-
H
L
R
T
-
A
--
Q
E
H
---------
D
-
K
R
D
P
V
V
A
Y
Y
C
R
L
Y
A
M
Q
T
G
M
K
I
D
S
-
K
T
-
P
E
C
R
K
F
L
S
K
L
M
D
Q
-------
L
E
A
L
K
K
Q
L
G
D
--------------------
N
--
E
A
I
----
T
----
Q
E
I
V
G
---
C
A
H
----
L
E
N
Y
------------------
A
L
K
----
M
-------------
F
L
-----------
Y
A
D
N
E
D
R
A
G
R
F
H
K
N
M
I
K
S
F
Y
T
A
-------
S
-
L
L
I
D
V
I
T
V
F
G
E
L
T
D
E
N
V
K
H
R
-------
K
Y
A
R
W
K
A
T
Y
I
H
N
C
L
K
N
------
G
E
T
P
Q
----
3
PsiBlast_PDB
48.73
26%
14
- C2 -
-
5HVO
2
?
A:
[219-337]
------------------------------------------------------------------------------------------
L
S
S
C
S
H
L
L
G
L
V
T
T
PS
S
V
K
Y
EG
R
S
-
V
-
A
V
G
-
A
----
F
P
I
G
I
D
P
D
K
-
F
T
D
G
-
L
--
K
S
P
---------
K
-
V
-
Q
N
R
I
A
S
-
L
E
N
K
F
Q
G
T
K
L
M
V
S
V
-
D
R
-
L
D
Y
I
K
G
I
P
Q
K
L
H
A
-------
L
E
V
F
L
Q
N
H
P
E
W
V
G
-
K
----
V
V
L
--------
V
--
Q
V
A
----
V
----
P
S
R
Q
D
---
V
E
E
----
Y
Q
N
L
------------------
R
A
V
------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
48.53
31%
-111
- C3 -
-
3UYJ
1
KDM8_HUMAN
A:
[60-126]
-----------------------------------------------------------------------------------------------
E
I
A
G
C
R
T
V
---------
P
-
V
-
E
V
G
-
S
----
R
Y
T
D
E
E
W
S
Q
-
T
L
M
T
------------------
V
N
E
F
I
S
K
Y
-
I
V
N
E
P
R
D
V
G
Y
L
A
Q
H
-
Q
L
-
F
D
Q
I
P
E
L
K
Q
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
47.34
31%
-89
- C3 -
-
4QU1
1
A:
[48-108]
-----------------------------------------------------------------------------------------------
E
I
A
G
C
R
T
V
---------
P
-
V
-
E
V
G
-
S
----
R
Y
T
D
E
E
W
S
Q
-
T
L
M
T
------------------
V
N
E
F
I
S
K
Y
-
I
V
N
E
P
R
D
V
G
Y
L
A
Q
H
-
Q
L
-
F
D
Q
I
P
E
L
K
Q
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
46.47
12%
60
- C2 -
-
1R30
4
BIOB_ECOLI
A:
[27-338]
---------R
P
R
W
T
L
S
Q
V
T
E
L
F
E
KP
L
L
D
L
L
F
E
A
Q
Q
V
H
R
Q
H
FDPR
Q
V
Q
V
S
T
L
L
S
I
K
T
G
A
C
P
E
-
D
C
K
Y
CPQSSRYKTGLEAERLME
V
E
Q
V
L
E
S
A
R
K
A
K
A
A
G
S
T
R
F
---------
C
-
M
-
G
A
A
-
W
KNPH
E
R
D
M
P
Y
L
E
Q
-
M
V
Q
G
-
V
--
K
A
M
G
L
E
A
C
M
T
LG
T
-
L
S
E
S
Q
A
Q
R
-
L
A
N
A
G
L
D
Y
Y
N
H
N
L
D
-
T
S
-
P
E
F
Y
G
N
I
I
T
T
-
R
T
-------
Y
Q
E
R
L
D
T
L
E
K
V
R
D
A
G
----
I
K
V
C
S
G
G
I
--
V
G
---
L
G
----
E
----
T
V
K
D
R
---
A
G
L
----
L
L
Q
L
------------------
A
N
L
----
P
TPPE
S
V
P
I
N
M
L
VK
V
K
-----------
G
T
P
L
A
D
N
D
D
V
D
A
F
D
F
I
R
T
I
A
V
A
R
I
M
M
P
T
S
Y
-
V
R
L
S
A
G
R
E
Q
M
N
E
Q
T
Q
A
M
C
F
M
A
GAN
S
I
-
F
Y
G
C
K
L
L
T
T
P
N
P
E
E
D
K
D
L
Q
L
F
R
K
L
G
L
N
PQQT
25
Fugue
46.05
20%
-5
- C2 -
-
2Q82
-
?
A:
[14-128]
-------------------------------------------------------------------------------------------
E
L
Q
N
R
L
A
Q
Y
E
T
S
---------
L
M
V
M
S
H
N
G
D
----
V
P
V
I
T
G
F
N
V
M
R
V
T
T
M
L
--
D
A
L
---------
K
-
V
P
--
A
V
A
V
-
L
G
D
D
A
Q
D
L
A
Y
V
F
G
A
-
R
P
-
L
A
V
G
V
N
I
I
---------------
R
V
V
D
V
P
G
Q
Q
P
-
S
----
A
L
V
D
A
E
L
G
--
A
L
--
H
E
V
----
S
----
M
-------
V
R
V
----
L
N
D
I
------------------
A
D
E
----
Q
-------------
L
V
-----------
K
A
N
--------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.75
25%
-89
- C2 -
-
5HVM
2
?
A:
[266-337]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
R
I
A
Q
-
L
E
Q
K
F
Q
G
V
K
L
M
V
G
V
-
D
R
-
L
D
Y
I
K
G
V
P
Q
K
L
H
A
-------
L
E
V
F
L
S
D
H
P
E
W
V
G
-
K
----
V
V
L
--------
V
--
Q
V
A
----
V
----
P
S
R
Q
D
---
V
E
E
----
Y
Q
N
L
------------------
R
A
V
------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
44.70
31%
-112
* C3 *
-
4AAP
1
KDM8_HUMAN
A:
[51-112]
-----------------------------------------------------------------------------------------------
E
I
A
G
C
R
T
V
---------
P
-
V
-
E
V
G
-
S
----
R
Y
T
D
E
E
W
S
Q
-
T
L
M
T
------------------
V
N
E
F
I
S
K
Y
-
I
V
N
--
R
D
V
G
Y
L
A
Q
H
-
Q
L
-
F
D
Q
I
P
E
L
K
Q
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
44.55
31%
-109
- C3 -
-
4GAZ
1
KDM8_HUMAN
A:
[56-122]
-----------------------------------------------------------------------------------------------
E
I
A
G
C
R
T
V
---------
P
-
V
-
E
V
G
-
S
----
R
Y
T
D
E
E
W
S
Q
-
T
L
M
T
------------------
V
N
E
F
I
S
K
Y
-
I
V
N
E
P
R
D
V
G
Y
L
A
Q
H
-
Q
L
-
F
D
Q
I
P
E
L
K
Q
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.21
25%
-13
- C2 -
-
4L9M
1
GRP1_HUMAN
A:
[405-463]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
W
A
S
-
G
----
V
-------------
S
P
K
----
P
----
D
P
K
T
I
---
S
K
H
----
V
Q
R
M
------------------
V
D
S
----
V
-------------
F
K
-----------
N
Y
D
H
D
Q
D
G
Y
I
S
Q
E
E
F
E
K
I
A
A
S
F
-------
P
-
F
S
F
C
V
M
D
K
--------------------------------------------------