@TOME V2.3
(Mar 2018)

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3D Common Core:

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Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : B0VKI9: (2017-10-26 )
MSEVLDVVIVGGGLVGGLTALLLAQGGVQPTVLDAAPVLDVEKTLSVMNPRVLALSQATIHLLKTVNVWDDLARQMPYTGMQVWNLNGYGEINFGHESVQRPISEQALGSMVEPSVLNVAIQQKMLEQLTDYRTQVRVTCIEQGVGCWHIQLADGTALKTKLLIGADGANSFVREQAFIDLDVLDYKQAAISCAIKTSKPHHYVARQIFLPTGPLAYLPMASLEESENGYWQSIVWTLPDDYADEYSALSDREFMQLLTRESQHMLGEVLDVRSRAQFPLKARAAKQYVKAGLALIGDAAHVIHPLAGQGVNIGCLDAAVLCDALLHDLGRGVWAHEQTLMRYEHRRKGQNDAMMHSMSAIGWLESSELFPLIWARNVGLKQVEQISFLKERFMQQANGLGALQNTQYSR

Atome Classification :

(20 SA) .........10........20........30...--.....40--........50--.........60......---..70.--...-.--...---80......--------..90.-.......100--........110.......---120......-.130.--....-------..140.---......150-.---.---.--....160----.........170.......180.......190.--------......--200-.----.---.---....----..--210.......220.......230..---------....-.240..-....-.250.......--.260.......270----........---280-.-----.....-.290..-.....300.......310.......320...--..-----..330....-...340.......350.......360-........370---.........380.......390.......400.......410----------------------------------------------------------------------------------------------------------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MSEVLDVVIVGGGLVGGLTALLLAQGGVQPTVLD--AAPVLDV--EKTLSVMNP---RVLALSQATIHLLKTVN---VWDDL--ARQ-M--PYT---GMQVWNLN--------GYGEI-NFGHESVQR---PISEQALGSMVEPSVLNV---AIQQKMLEQ-LTDYR--TQVR-------VTCIEQ---GVGCWHIQL-A---D---G--TALKT------KLLIGADGANSFVREQAFIDLDVLDYKQAAISC--------AIKTSK--P---H----H---Y---VARQ----IF--LPTGPLAYLPMASLEESENGYWQSI---------VWTL-PDDYAD-EYSA-LSD-REFMQLL--TRESQHMLGEVL-D----VRSRAQFP---LKA-R-----AAKQY-VKAGLA-LIGDAAHVIHPLAGQGVNIGCLDAAVLCDAL--LH-----DLGRGVWAH-EQTLMRYEHRRKGQNDAMMHSMSAI--GWLESSELF-----PLIWARNVGLKQVEQISFLKERFMQQANGLGALQNTQYSR------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 70.3136% -28 - C4 - - 4K22 UBII_ECOLI A:[2-350] --QSVDVAIVGGGMVGLAVACGLQGSGLRVAVLE--Q----R-----------PPQLRVSAINAASEKLLTRLG---VWQDILSRRA-S--CYH---GMEVWDKD--------SFGHI-SFDDQS-------MGYSHLGHIVENSVIHY---ALWNKA-HQ-SSDITLLAPAE-------LQQVAW---GENETFLTL-K---D---G--SMLTA------RLVIGADGANSWLRNKADIPLTFWDYQHHALVA--------TIRTEE--P---H----D---A---VARQ----VF--HGEGILAFLPLS------DPHLCSI---------VWSL-SPEEAQ-RMQQ-ASE-DEFNRAL--NIAFDNRLGLCK-V----ESARQVFP---LTG-R-----YARQF-ASHRLA-LVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH-----RQGKDI-GQ-YIYLRRYERSRKHSAALMLAGM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
105 HHSearch 69.7336% -47 - C4 - - 4K22 UBII_ECOLI A:[1-362] -MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLE--QR------------PPQL---RVSAINAASEKLLTRLG---VWQDIL-SRR-AS-CYH---GMEVWDKD--------SFGHI-SFDD----Q---SMGYSHLGHIVENSVIHY---ALWNKAHQSSDITLL--APAE-------LQQVAW---GENETFLTL-K---D---G--SMLTA------RLVIGADGANSWLRNKADIPLTFWDYQHHALVA--------TIRTEE--P---H----D---A---VARQ----VF--HGEGILAFLPLSDP------HLCSI---------VWSL-SPEEAQ-RMQQ-ASE-DEFNRAL--NIAFDNRLGLCK-V----ESARQVFP---LTG-R-----YARQF-ASHRLA-LVGDAAHTIHPLAGQGVNLGFMDAAELIAEL--KR-----LHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGF--RDLFSGTNP---------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 67.8433%-474 - C- - - 4N9X - ? A:[49-397] ---------------------------------------------------------RVSAINAASECLLRHIG---VWENL--VAQ-RVSPYN---DMQVWDKD--------SFGKI-SFSGEE-------FGFSHLGHIIENPVIQQ---VLWQRA-SQ-LSDI---TLLS-------PTSLKQVAWGENEAFITL-Q---D---D--SMLTA------RLVVGADGA---------------DYGHHALVA--------NIRTEH--P---H----Q---S---VARQ----AF--HGDGILAFLPL------DDPHLCSI---------VWSL-SPEQAL-VMQS-LPV-EEFNRQV--AMAFDMRLGLCE-L----ESERQTFP---LMG-R-----YARSF-AAHRLV-LVGDAAHTIHPLAGQGVNLGFMDVAELIAELKR----------KDIGQH-LYLRRYERRRK---HSAAVMLASMQ--GF---RELFDGDNPAKKLLRDVGLVLADKLPGIKPTLVRQAMGLHDLPD-----------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 67.3036% -28 - C4 - - 4K22 UBII_ECOLI B:[2-350] --QSVDVAIVGGGMVGLAVACGLQGSGLRVAVLE--Q--------------NAPPQLRVSAINAASEKLLTRLG---VWQDILSRRA-S--CYH---GMEVWDKD--------SFGHI-SFDDQS-------MGYSHLGHIVENSVIHY---ALWNKA-HQ-SSDITLLAPAE-------LQQVAW---GENETFLTL-K---D---G--SMLTA------RLVIGADGANSWLRNKADIPLTFWDYQHHALVA--------TIRTEE--P---H----D---A---VARQ----VF--HGEGILAFLPLS------DPHLCSI---------VWSL-SPEEAQ-RMQQ-ASE-DEFNRAL--NIAFDNRLGLCK-V----ESARQVFP---LTG-R-----YARQF-ASHRLA-LVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH-----RQGKDI-GQ-YIYLRRYERSRKHSAALMLAGM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
101 HHSearch 57.3734% -84 - C- - - 4N9X - ? A:[1-397] -MQSFDVVIAGGGMVGLALACGLQGSGLRIAVLE--KQ----------GKGHAL---RVSAINAASECLLRHIG---VWENLV-AQR-VS-PYN---DMQVWDKD--------SFGKI-SFSG----E---EFGFSHLGHIIENPVIQQ---VLWQRASQLSDITLL--SPTS-------LKQVAW---GENEAFITL-Q---D---D--SMLTA------RLVVGADGA---------------DYGHHALVA--------NIRTEH--P---H----Q---S---VARQ----AF--HGDGILAFLPLDDP------HLCSI---------VWSL-SPEQAL-VMQS-LPV-EEFNRQV--AMAFDMRLGLCE-L----ESERQTFP---LMG-R-----YARSF-AAHRLV-LVGDAAHTIHPLAGQGVNLGFMDVAELIAEL--KR----------KDIGQHLYLRRYERRRKHSAAVMLASMQGF--RELFDGDNP-----AKKLLRDVGLVLADKLPGIKPTLVRQAMGLHDLPD-----------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 55.4127% -5 - C4 - - 4J34 KMO_YEAST A:[3-359] -SE--SVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSIN------LAISARGIDALKSIDPDACEHIL--QDM-I--PMK---GRMIHDLK--------GR-------QESQLY---GLHGEAINS-INRSVLNN---SLLDELEKS-TTELK--FGHK-------LVKIEW---TDDKQICHF-A---I---G--EDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVE-MDFSQEYMNLRYIELYIPPTEEFK--P---N----YGGNF---AIAP----DH--LHIWPRHKFMLIALANSD-GSFTST---------FFGS-KDQISD-LITS-KSRVREFLI------ENFPDIINIM-DLDDAVKRFITYPKESLVC-V-----NCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILM-AL--LKKHSG-DRSRAFTEY-TQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 54.3127% -13 - C4 - - 4J33 KMO_YEAST A:[22-379] MSE--SVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSIN------LAISARGIDALKSIDPDACEHIL--QDM-I--PMK---GRMIHDLK--------GR-------QESQLY------GEAINS-INRSVLNN---SLLDELEKS-TTELK--FGHK-------LVKIEW---TDDKQICHF-A---I---G------TPHTEKYDFVIGCDGAYSATRSQMQRKVE-MDFSQEYMNLRYIELYIPPTEEFK--P---N----YGGNF---AIAP----DH--LHIWPRHKFMLIALANSD-GSFTST---------FFGS-KDQISD-LITS-KSRVREFLI------ENFPDIINIM-DLDDAVKRFITYPKESLVC-V-----NCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILM-AL--LKKHSG-DRSRAFTEY-TQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129 Fugue 53.4719% -45 - C4 - - 2QA1 ? A:[8-500] HRSDAAVIVVGAGPAGMMLAGELRLAGVEVVVLE--RLVE----------TGES---RGLGFTARTMEVFDQRG---ILPRF--GEV---------------ETS--------TQGHF-GGLPIDFGV---LEGAWQAAKTVPQSVTET---HLEQWATGL-GADIR--RGHE-------VLSLTD---DGAGVTVEV-RGPEG---K--HTLRA------AYLVGCDGGRSSVRKAAGFDFPGTAATMEMYLA--------DIKGVE--L---Q----P---R---MIGE----TL--PG-------GMVMVGPLPGGITRII---------VCER-GTP------PP-PSW-HEVADAW--KRLTGDDIAHA--E----PVWVSAFG---NAT-R-----QVTEY-RRGRVI-LAGDSAHIHLPAGGQGMNTSIQDAVNLGWKL--GA-----VVNG--TAT-EELLDSYHSERHAVGKRLLMNTQAQ--GLLFLSG-------PEVQPLRDVLTELIQYGEVARHLAGMVSGLEITYDVGTGSHPLLGKRMPALELTTATRETSSTELLHTARGVLLDLADNPRLRARAAAWSDRVDIVTAVPGEVSATSGLRDTTAVLIRPDGHVAWAAPGSHHDLPMALERWFGAPLTG
7 PsiBlast_PDB 53.1727% -20 - C4 - - 4J31 KMO_YEAST A:[23-379] -SE--SVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTT---NLKSIN------LAISARGIDALKSIDPDACEHIL--QDM-I--PMK---GRMIHDLK--------GR-------QESQLY------GEAINS-INRSVLNN---SLLDELEKS-TTELK--FGHK-------LVKIEW---TDDKQICHF-A---I----------TPHTEKYDFVIGCDGAYSATRSQMQRKVE-MDFSQEYMNLRYIELYIPPTEEFK--P---N----YGGNF---AIAP----DH--LHIWPRHKFMLIALANSD-GSFTST---------FFGS-KDQISD-LITS-KSRVREFLI------ENFPDIINIM-DLDDAVKRFITYPKESLVC-V-----NCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILM-AL--LKKHSG-DRSRAFTEY-TQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110 HHSearch 53.0018% -38 - C4 - - 4BJZ ? A:[3-376] NLQDARIIIAGGGIGGAANALALAQKGANVTLFE--RASEFG---------EVG---AGLQVGPHGARILDSWG---VLDDVL-SRA-F--LPK---NIVFRDAI--------TAEVLTKIDLGSE-F---RGRYGGPYFVTHRSDLHA---TLVDAARAA-GAELH--TGVT-------VTDVIT---EGDKAIVST-D---D---G--RTHEA------DIALGMDGLKSRLREKISGDEPV-SSGYAAYRG--------TTPYRD--VELDED---I---E---DVVG----YI--GPRCHFIQYPLRGG------EMLNQ---------VAVF-ESPGFKNGIENWGGP-EELEQAY--A-HCHENVRRGIDY----LWKDRWWP---MYDRE-----PIENW-VDGRMI-LLGDAAHPPLQYLASGAVMAIEDAKCLADYA--AE-----DFSTGGNSAWPQILKEVNTERAPRCNRILTTGRMW--GELWHLDG------TARIARNELF------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 52.6527% -6 - C4 - - 4J2W KMO_YEAST A:[22-379] MSE--SVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSIN------LAISARGIDALKSIDPDACEHIL--QDM-I--PMK---GRMIHDLK--------GR-------QESQLY------GEAINS-INRSVLNN---SLLDELEKS-TTELK--FGHK-------LVKIEW---TDDKQICHF-A---I---G------TPHTEKYDFVIGCDGAYSATRSQMQRKVE-MDFSQEYMNLRYIELYIPPTEEFK--P---N----YGGNF---AIAP----DH--LHIWPRHKFMLIALANSD-GSFTST---------FFGS-KDQISD-LITS-KSRVREFLI------ENFPDIINIM-DLDDAVKRFITYPKESLVC-V-----NCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILM-AL--LKKHSG-DRSRAFTEY-TQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 52.5627% -3 - C4 - - 4J36 KMO_YEAST A:[24-379] --E--SVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSIN------LAISARGIDALKSIDPDACEHIL--QDM-I--PMK---GRMIHDLK--------GR-------QESQLY-------EAINS-INRSVLNN---SLLDELEKS-TTELK--FGHK-------LVKIEW---TDDKQICHF-A---I---G--EDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVE-MDFSQEYMNLRYIELYIPPTEEFK--P---N----YGGNF---AIAP----DH--LHIWPRHKFMLIALANSD-GSFTST---------FFGS-KDQISD-LITS-KSRVREFLI------ENFPDIINIM-DLDDAVKRFITYPKESLVC-V-----NCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILM-AL--LKKHSG-DRSRAFTEY-TQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136 Fugue 52.5518% -13 - C4 - - 5DBJ ? D:[5-441] SDHDYDVVIIGGGPAGSTMASYLAKAGVKCAVFE--K-ELFER--EHVGESLVP----------ATTPVLLEIG---VMEKI--EKANF--PKK---FGAAWTSADSGPEDKMGFQGL-DHDFRSAEI---LFNERKQEGVDRDFTFHVDRGKFDRILLEH-AGSLG--AKVFQGVEIADVEFLSP---GNVIVNAKLGK---R---S--VEIKA------KMVVDASGRNVLLGRRLGLREKDPVFNQFAIHS--------WFD--------------N---F---DRKS----AT--QSPDKVDYIFIHFLPMTNTWVWQIPITETITSVGVVTQ-KQNYTN-SD---LTY-EEFFWEA--VKTRENLHDALK-A----SEQVRPFK---KEA-DYSY--GMKEV-CGDSFV-LIGDAARFVDPIFSSGVSVALNSARIASGDI--IEAVKNNDFSKSSFTH-YEGMIRNGIKNWYEFITLYYRLNILFTAFVQDPRYR-----LDILQLLQGDVYLEVLDKMREIIAAVESDPEHLWHKYLG-------------------------------------------------------------------------------------------------------------
111 HHSearch 51.9318% -37 - C4 - - 5HYM ? A:[3-376] NLQDARIIIAGGGIGGAANALALAQKGANVTLFE--RASEFG---------EVG---AGLQVGPHGARILDSWG---VLDDVL-SRA-F--LPK---NIVFRDAI--------TAEVLTKIDLGSE-F---RGRYGGPYFVTHRSDLHA---TLVDAARAA-GAELH--TGVT-------VTDVIT---EGDKAIVST-D---D---G--RTHEA------DIALGMDGLKSRLREKISGDEPV-SSGYAAYRG--------TTPYRD--VELDED---I---E---DVVG----YI--GPRCHFIQYPLRGG------EMLNQ---------VAVF-ESPGFKNGIENWGGP-EELEQAY--A-HCHENVRRGIDY----LWKDRWWP---MYDRE-----PIENW-VDGRMI-LLGDAAHPPLQYLASGAVMAIEDAKCLADYA--AE-----DFSTGGNSAWPQILKEVNTERAPRCNRILTTGRMW--GELWHLDG------TARIARNELF------------------------------------------------------------------------------------------------------------------------------------------
119 HHSearch 51.7822% -37 - C4 - - 2R0G ? A:[24-374] -PIETDVLILGGGPVGMALALDLAHRQVGHLVVE--QTDGTI---------THP---RVGTIGPRSMELFRRWG---VAKQIR-TAG-W--PGDHPLDAAWVTRVG-------GHEVY-RIPLGTADTRATPEHTPEPDAICPQHWLAP---LLAEAV----GERLR--TRSR-------LDSFEQ---RDDHVRATI-T---DLRTGATRAVHA------RYLVACDGASSPTRKALGIDAPPRHRTQVFRNI--------LFRAPE--L---RSLLGE---R---AALF----FF--LMLSSSLRFPLRAL---DGRGLYRL---------TVGV-D-------------T-MDSFELV--RRAVAF-DTEIE------VLSDSEWH---LTH-R-----VADSF-SAGRVF-LTGDAAHTLSPSGGFGMNTGIGSAADLGWKL--AA-----TLRGW--AG-PGLLATYEEERRPVAITSLEEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
102 HHSearch 51.4721% -25 - C4 - - 5KOX ? A:[4-375] ---MIDVIIAGGGPTGLMLAGELRLHGVRTVVLE--KEPTP---------NQHS---RSRGLHARSIEVMDQRG---LLERFL-AHG-E--QFR---VGGFFAGL--------A---A-EWPA----D---LDTAHSYVLAIPQVVTER---LLTEHATEL-GAEIR--RGCE-------VAGLDQ---DADGVTAEL-A---D---G--TRLRA------RYLVGCDGGRSTVRRLLGVDFPGEPTRVETLLA--------DVRIDV--P---V----E---TLTAVVAE----VR--KTQLRFGAVPAGD-------GFFRL---------IVPA-QGLSAD-R-AA-PTL-DELKRCL--HATAGTDF-GVH-S----PRWLSRFG---DAT-R-----LAERY-RTGRVL-LAGDAAHIHPPTGGQGLNLGIQDAFNLGWKL--AA-----AIGGW--AP-PDLLDSYHDERHPVAAEVLDNTRAQ--MTLLSLDP------GPRAVRRL-MAELVEFPDVNRHLIEKIT------------------------------------------------------------------------------------------------------------------------
109 HHSearch 51.1722% -21 - C4 - - 4K2X ? B:[21-388] --MRYDVVIAGAGPTGLMLACELRLAGARTLVLE--RLAEPV---------DFS---KALGVHARTVELLDMRG---LGEGFQ-AEA-P--KLR---GGNFASLG---------V-PL-DFSS--------FDTRHPYALFVPQVRTEE---LLTGRALEL-GAELR--RGHA-------VTALEQ---DADGVTVSV-T---GPEGP--YEVEC------AYLVGCDGGGSTVRKLLGIDFPGQDPHMFAVIA--------DARFREELP---H----G--------PYG----VMRHDLRAWFAAFPLEP-------DVYRA---------TVAFFDR------RAP-VTE-EDVRAAL--TEVAGSDF-GMH-D----VRWLSRLT---DTS-R-----QAERY-RDGRVL-LAGDACHIHLPAGGQGLNLGFQDAVNLGWKL--GA-----TIAGT--AP-PELLDTYEAERRPIAAGVLRNTRAQ--AVLIDP-DP-----RYEGLRELMIE-----------------------------------------------------------------------------------------------------------------------------------------
103 HHSearch 50.9621% -26 - C4 - - 5KOW ? A:[3-375] --HMIDVIIAGGGPTGLMLAGELRLHGVRTVVLE--KEPTP---------NQHS---RSRGLHARSIEVMDQRG---LLERFL-AHG-E--QFR---VGGFFAGL--------A---A-EWPA----D---LDTAHSYVLAIPQVVTER---LLTEHATEL-GAEIR--RGCE-------VAGLDQ---DADGVTAEL-A---D---G--TRLRA------RYLVGCDGGRSTVRRLLGVDFPGEPTRVETLLA--------DVRIDV--P---V----E---TLTAVVAE----VR--KTQLRFGAVPAGD-------GFFRL---------IVPA-QGLSAD-R-AA-PTL-DELKRCL--HATAGTDF-GVH-S----PRWLSRFG---DAT-R-----LAERY-RTGRVL-LAGDAAHIHPPTGGQGLNLGIQDAFNLGWKL--AA-----AIGGW--AP-PDLLDSYHDERHPVAAEVLDNTRAQ--MTLLSLDP------GPRAVRRL-MAELVEFPDVNRHLIEKIT------------------------------------------------------------------------------------------------------------------------
131 Fugue 50.0914% -43 - C4 - - 3E1T ? A:[5-503] -PEVFDLIVIGGGPGGSTLASFVAMRGHRVLLLE--REAFPRH--QIGESL----------LPATVHGICAMLG---LTDEM--KRA-G--FPI---KRGGTFRW--------GKEPE-PWTFGFTRH---PDDPYGFAYQVERARFDD---MLLRNSERK-GVDVR--ERHE-------VIDVLFEGERAVGVRYRN-T---E---GVELMAHA------RFIVDASGNRTRVSQAVGERVYSRFFQNVALYG--------YFENGK--R---L----P---A---PRQGNILSAA--FQDGWFWYIPL-------SDTLTSV---------GAVV-SREAAE-AIKD-GHE-AALLRYIDRCPIIKEYLAPAT-R----VTTGDYGE---IRI-RKDYSYCNTSF-WKNGMA-LVGDAACFVDPVFSSGVHLATYSALLVARAI--NT-----CL-AGEMSE-QRCFEEFERRYRREYGNFYQFLVAF--YDMNQDTDS-----YFWSARKIINTEERANEAFVRLIAGRSNLDEPVFQSNFMQGFTREITELQHLAMFGLVPSRDGLAWA---------------------------------------------------------------------------------
104 HHSearch 49.1321% -17 - C4 - - 2QA1 ? A:[8-349] HRSDAAVIVVGAGPAGMMLAGELRLAGVEVVVLE--RLVE-T---------GES---RGLGFTARTMEVFDQRG---ILPRFG-EVE-T--STQ----GH-FG----------GL-PI-DFGV--------LEGAWQAAKTVPQSVTET---HLEQWATGL-GADIR--RGHE-------VLSLTD---DGAGVTVEV-R---GPEGK--HTLRA------AYLVGCDGGRSSVRKAAGFDFPGTAATMEMYLA--------DIKGVE--L---Q--------P---RMIG----ET--LPGGMVMVGPLPG-------GITRI---------IVCE-RGTPP-----P-PSW-HEVADAW--KRLTGDDI-AHA-E----PVWVSAFG---NAT-R-----QVTEY-RRGRVI-LAGDSAHIHLPAGGQGMNTSIQDAVNLGWKL--GA-----VVNGT--AT-EELLDSYHSERHAVGKRLLMNTQAQ--GLLF--------------------------------------------------------------------------------------------------------------------------------------------------------------