@TOME V2.3
(Mar 2018)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKJ3: (2017-10-26 )
MVMLSLSVFFKGLGIGSGLIVAIGAQNAFVLKQGLKQQYVFWLCLICALSDSILIACGVLGFAEIMTASPILITVAKYLGATFLFVYGAKAFYAAFKTNQGMELDSSQKQTLTQALITCLAFTWLNPHVYLDTIVLIGSVATQLEDKISFALGSILASWIFFFSLGYGARFLKPLFINPKAWKILDFMIGCVMWSIAISLLI
Atome Classification :
(13 SA)
---------------------------------------------------------------------------------------------.........10..------......20-----..-.--......30------...-------...-..40-...------------------....---.-.50..-......60--------------------.--.....--...70........80..---.--------------....-----.------.90.....-----..-.----100-.-.--.....-.110....---....120.------------.-..------------...130..--..-----.---------..140...------...---------------.150-------.......160-------...---....170--.....-..180......----.190....-------...200.------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------
M
V
M
L
S
L
S
V
F
F
K
G
L------GIGS
G
L
I
------
V
A
-I--GAQ
N
A
F
V
L
------
K
Q
G
-------
L
K
Q
-
Q
Y
V
--
F
W
L
------------------
C
L
I
C
---
A
-LSD
S
I
-
L
I
A
C
G
V
L
---------------------
G
--
F
A
E
I
M--TAS
P
I
L
I
T
V
A
K
Y
L
G
-
A
T
---
F
--------------
L
F
V
Y-----G------
A
K
A
F
Y
A
A
F-----KT-N----QG--M-E--LD
S
S
Q
-
K
Q
T
-
L
T
Q
A
---
L
I
T
C
L
A
F
T
------------W-LN------------PH
V
Y
L
D
T
I
--
V
L
-----
I
---------
G
S
V
A
T
Q
L
E
------
D
K
I
---------------
S
F
A
L
-------
G
S
I
L
A
S
W
I
F
F
-------
F
SL---GYGARF
L
--
K
P
L
F
I-NP
K
A
W
K
I
L
D
F
M
----
I
G
C
V
M
W
S
I
-------
A
I
S
L-LI------------------------------
16
Fugue
80.40
25%
-74
* C3 *
-
3W6S
1
?
A:
[19-243]
------------------------------------------------------------------------------------------------------------------------------
S
-
I
--
E
W
K
L
T
A
N
L
------
R
N
G
-------
P
T
F
-
F
Q
-------------------------------
P
-
L
A
D
S
I
E
P
L
Q
F
K
L
I
---------------------
G
--
S
D
T
V
A
--
T
A
F
P
V
F
--
D
T
K
Y
I
P
-
D
S
------------------
L
I
N
Y
-----
L
------
F
K
L
F
N
L
E
I
-----
E
S
-
G
----
K
T
--
Y
P
Q
--
L
H
S
L
T
-
K
Q
G
-
F
L
N
Y
---
W
F
H
S
F
A
V
V
------------
V
-
L
Q
TDEK
F
I
Q
D
NQDW
N
S
V
L
L
G
T
F
--
Y
I
-----
K
PNYAPRCSH
N
C
N
A
G
F
L
V
N
GAHRG
Q
K
V
---------------
G
Y
R
L
-------
A
Q
V
Y
L
N
W
A
P
L
-------
L
-----
G
Y
K
Y
S
I
F
--
N
L
V
F
V
T
N
Q
A
S
W
K
I
W
D
K
L
NFQR
I
G
L
V
P
H
A
G
ILNGFS
E
P
V
D
A
-
I
I
Y
G
K
D
LTKIEPEFLSME--------------
14
Fugue
66.02
23%
-114
- C3 -
-
5MUW
2
P4_BPPH6
A:
[2-276]
-------------------------------------------------------------------------P
I
V
V
T
Q
A
H
I
D
R
V
G
I
A
A
D
L
L
D
A
S
P
V
S
L
Q
V
L
G
R
P
T
------
A
I
N
T
V
V
I
------
K
T
Y
I
--
A
A
V
M
E
L
A
S
------
K
Q
G
GSLAGVD
I
R
P
-
S
V
L
--
L
K
D
------------------
T
A
I
F
TAD
V
-
E
S
D
V
D
-
V
L
D
T
G
I
Y
S
VPGLARKPVTHRWPSEGI
Y
S
G
--
V
T
A
L
M
GA
T
G
S
G
K
S
I
T
L
N
E
K
L
R
-
P
D
---
V
--------------
L
I
R
W
-----
G
------
E
V
A
-
E
A
Y
D
-----
E
L
-
D
----
T
A
--
V
-
H
--
I
S
------
T
-
L
D
E
M
---
L
I
V
C
I
G
L
G
------------
A
-
L
G
------------
F
N
V
A
V
D
S
V
R
P
L
L
-----
F
---------
R
L
K
G
A
A
S
A
------
G
G
I
---------------
V
A
V
F
-------
Y
S
L
L
T
D
I
S
N
L
-------
F
T
Q
---
Y
D
C
S
V
V
M
VV
N
P
M
V
D
-
A
E
K
----
I
E
Y
V
----
F
G
Q
V
M
A
S
T
-------
V
G
A
I
-
L
C
A
DGNVS
R
T
M
F
RTNKGRIFN-----------
10
Fugue
58.38
17%
-67
- C2 -
-
4NTC
1
GLIT_ASPFU
A:
[2-326]
MS
I
G
K
L
L
SNG
A
L
L
V
DVLIIGAG
P
A
G
L
S
T
A
T
G
L
A
R
Q
L
H
T
A
V
V
F
D
SGVYRNAKTQHMHNVLGWDHRN
P
A
E
L
R
A
A
G
R
A
D
L
T
TRYST
I
Q
F
Q
NSTIE
A
I
R
Q
V
E
T
N
Q
L
F
E
A
R
D
NEG
H
S
W
Y
G
R
K
V
V
------
L
A
-
T
--
G
V
R
D
I
P
L
D
------
I
E
G
-------
Y
S
E
-
C
W
A
NG
I
Y
H
------------------
C
L
F
C
---
D
G
Y
E
E
R
G
-
Q
E
T
V
G
V
L
---------------------
A
--
L
G
P
I
A
--
N
P
A
R
A
L
H
L
A
R
M
A
L
R
L
S
E
---
S
--------------
V
T
I
Y
-----
T
NGN
E
Q
L
A
K
E
I
Q
Q
A
A
-----
E
E
-
S
PVGA
S
G
--
L
-
K
--
F
E
A
R
P
-
I
R
R
-
F
E
K
G
---
D
V
A
K
T
V
I
V
------------
H
-
L
G
------------
E
S
E
S
K
T
E
G
--
F
L
-----
V
---------
Y
N
P
Q
T
E
V
N
------
G
P
F
---------------
A
K
Q
L
ALNMTEG
G
D
I
L
T
T
P
P
F
Y
ETSVPG
V
F
A
V
---
G
D
C
A
T
P
L
--
K
A
----
V
T
P
A
V
S
M
G
S
L
A
----
A
G
G
L
V
A
Q
L
-------
Q
A
Q
A
-
L
-------------------------------
12
Fugue
58.37
17%
-76
- C1 -
-
4ECF
9
?
A:
[2-261]
--------------------------------------------------------------------A
G
E
S
I
T
A
V
G
STAL
Q
P
L
V
E
A
A
G
E
Q
Y
T
G
E
H
L
G
T
F
I
N
V
Q
G
G
------
G
T
G
T
G
L
S
Q
I
Q
E
GA
V
Q
-
I
--
G
N
S
D
L
F
A
G
EQKGIN
A
R
Q
-------
L
V
D
-
H
R
V
--
A
V
V
------------------
G
I
T
P
---
I
-
V
N
K
K
V
-
G
V
--
K
N
L
---------------------
S
--
T
N
Q
L
I
--
K
I
F
T
G
Q
I
T
N
W
K
E
V
G
-
G
A
D
Q
S
I
--------------
V
L
I
N
R
A
QGS
G
------
T
R
A
T
F
E
Q
F
GLAN
H
R
S
-
K
----
T
A
--
Q
-
E
--
Q
D
S
S
G
M
V
R
S
-
I
V
A
T
TPG
A
I
S
Y
V
A
F
S
------------
Y
-
V
N
------------
K
T
V
Q
A
L
S
L
--
N
H
-----
V
---------
A
P
T
E
V
N
V
T
------
T
N
----------------
D
W
R
I
-------
W
S
Y
E
H
L
Y
T
K
G
-------
H
P
T
---
G
L
T
K
A
F
I
--
T
Y
V
Q
S
-
P
A
I
Q
N
T
L
V
R
Q
L
---------
G
Y
L
-------
S
P
D
Q
M
L
V
E
R
D
ANG
H
I
T
K
T-------------------
11
Fugue
53.68
13%
-127
- C2 -
-
5EIK
6
T38B2_CAEEL
A:
[10-243]
---------------------------------------------------------------------------------I
D
H
D
T
L
I
D
A
G
G
Y
V
Q
K
L
K
L
Y
P
Y
F
D
A
A
------
H
Y
V
L
T
C
L
------
S
V
-
R
--
H
D
L
G
P
D
A
I
------
S
F
S
-------
R
K
H
-
P
F
S
--
C
W
L
------------------
S
C
M
L
---
M
-
S
F
A
G
S
-
F
L
S
C
F
L
L
---------------------
G
EP
I
I
S
P
L
--
K
Q
H
A
D
I
L
L
G
S
I
V
W
Y
-
L
V
---
F
--------------
Y
S
P
F
-----
D
------
V
V
F
R
L
A
T
W
-----
F
P
-
V
----
K
L
--
G
-
L
--
S
V
L
K
E
-
V
Q
R
-
T
H
K
I
---
A
A
G
V
K
H
A
V
------------
R
-
I
Y
------------
P
E
S
Y
L
V
Q
I
--
L
V
G
V
A
K
G
A
---------
G
S
G
V
V
K
I
V
------
E
Q
L
A
R
G
T
W
H
P
TNHE
I
L
R
P
S
F
T
T
-------
K
A
C
V
I
A
S
I
V
F
-------
T
L
E
---
R
H
S
M
Y
V
T
--
A
P
--
H
-
D
L
V
Y
L
C
V
V
G
F
F
----
I
Y
F
K
L
A
S
L
-------
C
L
S
V
-
H
D
------------------------------
9
Fugue
48.26
18%
-92
- C3 -
-
5JBL
-
PCPP_BPT4
A:
[21-191]
-------------------------------------------------------------------------------------------------
N
E
P
Q
L
L
I
E
T
------
W
G
Q
P
G
E
I
------
I
D
-------
G
V
P
M
L
------
E
S
G
-------
L
K
P
G
L
Y
I
--
E
G
I
------------------
F
L
Q
A
---
E
-
V
V
N
R
N
-
K
--------------------------------
R
L
Y
--
P
K
R
I
L
E
K
A
V
K
D
Y
I
N
-
E
Q
---
V
--------------
L
T
---------------------------
K
Q
-
A
----
L
G
--
E
-
L
--
N
A
P
P
R
-
A
N
V
D
P
M
Q
A
---
A
I
I
I
E
D
M
W
------------
W
-
K
G
------------
N
D
V
Y
G
R
A
R
--
V
I
-----
E
---------
G
D
-----
H
------
G
P
G
---------------
D
K
L
A
-------
A
N
I
R
A
G
W
I
P
--------------
G
V
A
S
R
G
L
--
G
S
L
T
D
-
T
N
E
G
Y
R
I
V
N
E
G
---------
F
K
L
-------
T
V
G
V
-
D
A
V
W
G---------------------------
15
Fugue
45.48
16%
-96
* C2 *
-
5TSZ
-
?
A:
[13-142]
--------------------------------------------------------------------------------------------------------------------------------------------------
S
S
-------
L
E
G
-
G
S
E
--
F
S
E
------------------
R
I
G
N
---
S
-
L
S
S
F
L
-
S
E
S
A
S
L
E
---------------------
V
--
I
G
N
E
L
--
A
D
N
I
A
N
E
I
V
S
S
L
Q
K
-
D
S
---
A
--------------
S
F
L
Q
-----
S
------
G
F
D
V
K
T
Q
L
-----
K
A
-
T
----
A
K
--
K
-
V
--
L
V
E
A
L
-
K
A
A
-
L
E
P
T
---
E
K
I
-
V
A
S
T
------------
I
-
K
P
------------
P
R
V
S
E
D
A
Y
--
F
L
-----
L
---------
G
P
V
V
K
T
L
F
------
N
K
V
---------------
E
D
V
L
-------
H
K
P
I
P
D
T
I
W
E
-------
Y
---------------------------------------------------------------------------------------
8
Fugue
38.40
9%
-101
- C2 -
-
3HAM
3
?
A:
[1-299]
-------------------------------------------------------------------------MVNLD
A
E
I
Y
E
H
L
N
K
Q
IKIN
E
L
R
Y
L
S
S
G
D
D
S
D
T
F
------
L
C
N
E
Q
Y
V
------
V
K
-
V
--
P
K
R
D
S
V
R
I
------
S
Q
K
-------
R
E
F
-
E
L
Y
--
R
F
L
E
NCKLSYQIPAVVYQSDR
F
N
I
M
---
K
-
Y
I
K
G
E
-
R
I
T
Y
E
Q
Y
---------------------
H
--
K
L
S
E
K
--
E
K
D
A
L
A
Y
D
E
A
T
F
L
K
-
E
L
---
H
S
IEIDCSVSLFSDA
L
V
N
K
-----
K
------
D
K
F
L
Q
D
K
K
-----
L
L
-
I
----
S
I
--
L
-
E
--
K
E
Q
L
L
-
T
D
E
-
M
L
E
H
---
I
E
T
I
Y
E
N
I
L
N
NAVLF
K
Y
T
P
C
L
-
V
H
------------
N
D
F
S
A
N
N
M
--
I
F
-----
R
---------
N
N
R
L
F
G
V
I
------
D
F
G
---------------
D
F
N
V
-------
G
D
P
D
N
D
F
L
C
L
-------
L
D
C
STD
D
F
G
K
E
F
G
--
R
K
V
L
K
-
Y
Y
Q
H
K
A
P
E
V
A
E
----
R
K
A
E
L
N
D
V
-------
Y
W
S
I
-
D
Q
I
I
Y
G
Y
E
R
KD
R
E
M
L
I
K
G
V
S
E
L
L
Q
TQAEMFIF
1
HHSearch
36.21
9%
-142
- C4 -
-
2N4X
-
?
A:
[11-194]
-----------------------------------------------------------------------------------------------------
Q
L
M
A
F
------
A
L
G
I
L
S
V
------
F
S
-
P
AV
L
P
V
V
P
L
I
F
------
A
G
S
-------
R
G
R
A
L
D
A
--
F
L
I
------------------
V
A
G
L
---
T
-
I
S
M
L
I
-
L
G
Y
T
A
S
L
---------------------
F
---
F
------------
G
F
F
R
V
V
A
-
M
L
---
F
--------------
L
L
I
F
-----
A
------
L
I
L
L
S
D
E
L
-----
D
E
K
V
----
S
I
F
A
S
-
R
M
T
S
G
L
S
W
-
K
I
Q
-
T
L
P
S
---
F
F
F
G
M
L
L
A
------------
F
L
W
L
------------
P
A
I
L
P
F
A
G
--
I
A
-----
I
---------
S
Q
T
L
L
S
E
N
--------
P
---------------
L
V
M
L
-------
S
Y
G
L
G
M
A
V
T
I
-------
A
A
V
---
F
K
M
G
E
-----
K
F
V
K
---
A
N
F
Q
L
I
R
K
V
----
T
G
A
I
V
L
L
Y
-------
L
A
Y
F
-
A
-------------------------------
6
HHSearch
31.22
20%
-258
- C4 -
-
1WAZ
-
?
A:
[28-67]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
L
L
G
V
V
---------------------
G
--
L
S
A
L
T
--
G
Y
---
L
D
Y
V
L
L
P
A
L
-
A
I
---
F
--------------
I
G
L
T
-----
I
------
Y
A
I
Q
R
K
R
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
28.33
13%
-335
* C4 *
-
2M67
-
?
A:
[24-70]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
P
V
L
V
I
L
L
---------------------
G
--
V
V
G
L
S
--
A
L
T
G
Y
L
D
Y
V
L
L
P
A
L
-
A
I
---
F
--------------
I
G
L
T
-----
I
------
Y
A
I
Q
R
K
R
Q
-----
A
D
-
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
20.69
0%
-442
- C4 -
-
3S8F
3
COXA_THET8
C:
[21-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
W
L
-------
G
V
Y
---
A
V
F
F
A
-----------------------------------------------------------------------------
3
HHSearch
14.89
15%
-160
- C4 -
-
2LJ2
-
?
A:
[43-68]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Y
V
L
L
P
A
L
-
A
I
---
F
--------------
I
G
L
T
-----
I
------
Y
A
I
Q
R
K
R
Q
-----
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------