@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKK4: (2017-10-26 )
MISLSDLRKFKAEGRKFSCLTCYDASMAKAMELAEIDTILIGDSLGMAIQGRDSTLPVTVEDMAYHTAAVRRGNQHALIMTDLPFMSYATLKDALQNAKTVMQAGAQMIKIEGGAWLSETVQVLTRNGVPVCVHLGLTPQSVHVFGGYKLQARTREAADQLIADCTAVVEAGAAVLLLECVPAQLGQEIAELFPNTPVIGIGAGNATDGQVLVVQDMLGLTFGRVARFVRNFMKEQSGETAILDAFKAFHAAVQDQSFPAKEHTFQVEL
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........-90..-......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.-......230.......240.......250.......260.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MI
S
L
S
D
L
R
K
F
K
AEG
R
K
F
S
C
L
T
CY
D
A
S
M
A
K
A
M
E
L
A
E
I
D
T
I
L
IGDSL
G
M
A
IQGRDSTL
P
V
T
V
E
D
M
A
Y
H
T
A
A
VRRGN
Q
H
A
L
I
M
TDLP
F
M
S
Y
A
-
T
L
K
D
-
A
L
Q
N
A
K
T
V
M
Q
AGA
Q
M
I
K
IEGG
A
W
L
S
E
T
V
Q
V
L
TRNG
V
P
V
C
V
HLGLTP
Q
S
V
H
V
FG
G
Y
K
L
Q
A
R
T
R
E
A
A
D
Q
L
I
A
D
C
T
A
V
V
EAG
A
A
V
L
L
L
E
C
V
P
A
Q
L
G
Q
E
I
A
E
LFPNT
P
V
I
G
I
GAGNATD
G
Q
V
L
V
V
Q
D
M
L
G
L
T
F
G
-
R
V
A
R
F
V
R
N
F
M
K
EQSG
E
T
A
I
L
D
A
F
K
A
F
H
A
A
VQDQSFPAK
E
H
T
F
Q
VEL
14
PsiBlast_CBE
94.62
54%
-142
- C5 -
-
1M3U
1
PANB_ECOLI
D:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
A
F
G
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
A
E
-
T
G
D
--
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
1
PsiBlast_PDB
94.07
54%
-136
- C5 -
-
1M3U
1
PANB_ECOLI
A:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
A
F
G
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
A
E
-
T
G
D
--
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
35
Fugue
93.42
54%
-136
- C5 -
-
1M3U
1
PANB_ECOLI
A:
[3-264]
P
T
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
A
F
G
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
A
E
T
G
---
D
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
16
PsiBlast_CBE
93.01
54%
-138
- C5 -
-
1M3U
1
PANB_ECOLI
B:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
---------
I
P
K
F
A
K
N
F
L
A
E
-
T
G
D
--
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
12
PsiBlast_CBE
92.96
54%
-143
- C5 -
-
1M3U
1
PANB_ECOLI
F:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
A
F
G
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
--------
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
15
PsiBlast_CBE
92.52
54%
-137
- C5 -
-
1M3U
1
PANB_ECOLI
C:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
A
F
G
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
A
E
-
T
G
D
--
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
46
HHSearch
92.30
51%
-137
- C5 -
-
3VAV
1
PANB_BURTA
H:
[15-275]
A
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
G
G
F
K
V
Q
G
K
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
S
-
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
G
Q
---
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
13
PsiBlast_CBE
91.76
54%
-133
- C5 -
-
1M3U
1
PANB_ECOLI
E:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
---
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
A
E
-
T
G
D
--
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
25
PsiBlast_CBE
91.43
50%
-137
- C5 -
-
3VAV
2
PANB_BURTA
B:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
G
G
F
K
V
Q
G
K
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
----
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
47
HHSearch
91.27
54%
-118
- C5 -
-
1M3U
1
PANB_ECOLI
C:
[3-264]
P
T
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
I
F
G
G
Y
K
V
Q
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
L
V
M
H
D
A
F
G
I
T
-
G
G
H
I
P
K
F
A
K
N
F
L
A
E
T
---
G
D
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
17
PsiBlast_CBE
91.13
50%
-139
- C5 -
-
3VAV
2
PANB_BURTA
J:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
G
G
F
K
V
Q
G
K
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
2
PsiBlast_PDB
91.04
50%
-141
- C5 -
-
3VAV
1
PANB_BURTA
A:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
G
---
V
Q
G
K
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
19
PsiBlast_CBE
91.01
50%
-137
- C5 -
-
3VAV
1
PANB_BURTA
H:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
G
G
F
K
V
Q
G
K
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
22
PsiBlast_CBE
90.44
50%
-144
- C5 -
-
3VAV
2
PANB_BURTA
E:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
------------
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
45
HHSearch
90.26
51%
-156
- C5 -
-
3VAV
3
PANB_BURTA
G:
[15-275]
A
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
--------------------
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
S
-
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
-----
R
F
V
K
D
F
M
Q
G
Q
---
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
23
PsiBlast_CBE
89.78
50%
-140
- C5 -
-
3VAV
1
PANB_BURTA
D:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
----
V
Q
G
K
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
8
PsiBlast_CBE
89.73
54%
-137
- C5 -
-
1M3U
4
PANB_ECOLI
J:
[5-264]
--
T
I
S
L
L
Q
K
Y
K
Q
E
K
K
R
F
A
T
I
T
A
Y
D
Y
S
F
A
K
L
F
A
D
E
G
L
N
V
M
L
V
G
D
S
L
G
M
T
V
Q
G
H
D
S
T
L
P
V
T
V
A
D
I
A
Y
H
T
A
A
V
R
R
G
A
P
N
C
L
L
L
A
D
L
P
F
M
A
Y
A
-
T
P
E
Q
-
A
F
E
N
A
A
T
V
M
R
A
G
A
N
M
V
K
I
E
G
G
E
W
L
V
E
T
V
Q
M
L
T
E
R
A
V
P
V
C
G
H
L
G
L
T
P
Q
S
V
N
--------
G
R
G
D
E
A
G
D
Q
L
L
S
D
A
L
A
L
E
A
A
G
A
Q
L
L
V
L
E
C
V
P
V
E
L
A
K
R
I
T
E
A
L
A
-
I
P
V
I
G
I
G
A
G
N
V
T
D
G
Q
I
--
M
H
D
A
F
G
I
T
G
G
-
H
I
P
K
F
A
K
N
F
L
--------
I
R
A
A
V
R
Q
Y
M
A
E
V
E
S
G
V
Y
P
G
E
E
H
S
F
H
---
24
PsiBlast_CBE
89.58
50%
-153
- C5 -
-
3VAV
2
PANB_BURTA
C:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
--------------------
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
26
PsiBlast_CBE
89.21
49%
-149
- C5 -
-
3EZ4
1
PANB_BURP1
J:
[9-269]
M
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
S
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
A
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
G
L
V
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
L
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
-------------------
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
P
G
-
K
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
21
PsiBlast_CBE
89.02
50%
-143
- C5 -
-
3VAV
1
PANB_BURTA
F:
[16-275]
-
V
T
V
P
K
L
Q
A
M
R
E
A
G
E
K
I
A
M
L
T
C
Y
D
A
S
F
A
A
L
L
D
R
A
N
V
D
V
Q
L
I
G
D
S
L
G
N
V
L
Q
G
Q
T
T
T
L
P
V
T
L
D
D
I
A
Y
H
T
A
C
V
A
R
A
Q
P
R
A
L
I
V
A
D
L
P
F
G
T
Y
G
-
T
P
A
D
-
A
F
A
S
A
V
K
L
M
R
A
G
A
Q
M
V
K
F
E
G
G
E
W
L
A
E
T
V
R
F
L
V
E
R
A
V
P
V
C
A
H
V
G
L
T
P
Q
S
V
H
A
F
G
-------
T
E
A
G
A
A
Q
L
L
R
D
A
R
A
V
E
E
A
G
A
Q
L
I
V
L
E
A
V
P
T
L
V
A
A
E
V
T
R
E
L
-
S
I
P
T
I
G
I
G
A
G
A
E
C
S
G
Q
V
L
V
L
H
D
M
L
G
V
F
----
R
P
R
F
V
K
D
F
M
Q
---
G
Q
P
S
I
F
A
A
V
E
A
Y
V
R
A
V
K
D
G
S
F
P
G
P
E
H
S
F
----
50
HHSearch
84.21
49%
-76
- C5 -
-
1O68
1
PANB_NEIMB
D:
[3-263]
L
I
T
V
N
T
L
Q
K
M
K
A
A
G
E
K
I
A
M
L
T
A
Y
E
S
S
F
A
A
L
M
D
D
A
G
V
E
M
L
L
V
G
D
S
L
G
M
A
V
Q
G
R
K
S
T
L
P
V
S
L
R
D
M
C
Y
H
T
E
C
V
A
R
G
A
K
N
A
M
I
V
S
D
L
P
F
G
A
Y
Q
Q
S
K
E
Q
-
A
F
A
A
A
A
E
L
M
A
A
G
A
H
M
V
K
L
E
G
G
V
W
M
A
E
T
T
E
F
L
Q
M
R
G
I
P
V
C
A
H
I
G
L
T
P
Q
S
V
F
A
F
G
G
Y
K
V
Q
G
R
G
G
-
K
A
Q
A
L
L
N
D
A
K
A
H
D
D
A
G
A
A
V
V
L
M
E
C
V
L
A
E
L
A
K
K
V
T
E
T
V
S
-
C
P
T
I
G
I
G
A
G
A
D
C
D
G
Q
V
L
V
M
H
D
M
L
G
I
F
P
G
-
K
T
A
K
F
V
K
N
F
M
Q
G
H
---
D
S
V
Q
A
A
V
R
A
Y
V
A
E
V
K
A
K
T
F
P
A
A
E
H
I
F
----
5
PsiBlast_PDB
79.23
46%
-86
- C5 -
-
1O68
1
PANB_NEIMB
A:
[3-263]
L
I
T
V
N
T
L
Q
K
M
K
A
A
G
E
K
I
A
M
L
T
A
Y
E
S
S
F
A
A
L
M
D
D
A
G
V
E
M
L
L
V
G
D
S
L
G
M
A
V
Q
G
R
K
S
T
L
P
V
S
L
R
D
M
C
Y
H
T
E
C
V
A
R
G
A
K
N
A
M
I
V
S
D
L
P
F
G
A
Y
Q
-
Q
S
K
E
Q
A
F
A
A
A
A
E
L
M
A
A
G
A
H
M
V
K
L
E
G
G
V
W
M
A
E
T
T
E
F
L
Q
M
R
G
I
P
V
C
A
H
I
G
L
T
P
Q
S
V
F
A
-----------
K
-
A
Q
A
L
L
N
D
A
K
A
H
D
D
A
G
A
A
V
V
L
M
E
C
V
L
A
E
L
A
K
K
V
T
E
T
V
-
S
C
P
T
I
G
I
G
A
G
A
D
C
D
G
Q
V
L
V
M
H
D
M
L
G
I
F
P
G
-
K
T
A
K
F
V
K
N
F
M
Q
---
G
H
D
S
V
Q
A
A
V
R
A
Y
V
A
E
V
K
A
K
T
F
P
A
A
E
H
I
F
----