@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKK6: (2017-10-27 )
MQTLRASKCGLSTAQLPSSILDVIDSLTKAGYEAYIVGGGVRDLMLGLNPKDFDAVTNATPSQIKEVFGRRCRIIGRRFELAHVYSGRELIEVATFRAPPKKAVTSASGMILRDNNWGTIEQDFARRDFSINTLYYQPRKGIVLDFCKAIDDVKSKTLRLLGDPVQRFEEDPVRMLRTLRFAAKLNFKIDPAILDIFDVEMTQLLRDVSPHRLYDESQKLFTMGHLARVLPMLIAFGVWKQLFADIRPDLTPFIQRAAKNTDQRIQVGKTINPAFFYAVLLWQPFLERCDFYLSKGVVPAEARAQAGLDVLKRQATRTVIPRFAETFIREVWEMQTRLLNPKPQQIEALASHARFRAGFDFLLLREKSGDDTTQGMGSWWEAYQEMSNDEKEAAISQYNRQKAKSRRKVAAEPVESNKVDTEIEPLVDVPEPRSRRGKKERARQEQSIDRFIEKSSAAQTNVMSDHPILKRKRVQRDLSQVIFGPTQ
Atome Classification :
(31 SA)
-.........10........20.......----.30----........40........---50........60.......-.70---..---....---..80..-----....----.---.90......---..100.......110.-......120.......130.......---140------.........150.......160.......170.......180....---..---.190.......200--.......210.......220.......230.......240......--------.250-------.--------.......260....---.-------------------..-270-.......280-.......290..-......300.......310.......320.......330.......340.......350.......360...-....-370........380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-MQTLRASKCGL
S
T
A
Q
L
P
S
S
I
L
D
V
I
D
S
L
T
----KAG----
Y
E
A
Y
I
VGG
G
V
R
D
L
M
LGLN---P
K
D
F
D
A
VTNA
T
P
S
Q
I
K
E
V
F
-
G
R
R
---
C
R
---
I
IGR---
R
F
E
L
A
H
-----VYSG----
R
---
E
L
I
E
V
ATFR---AP
P
K
K
AVTSAS
G
M
I
L
R-DNNWG
T
I
E
Q
D
F
A
RRDFSIN
T
L
Y
YQPR---K--------
G
I
V
L
D
F
C
K
A
I
D
D
V
K
S
K
T
L
R
L
LG
D
P
V
Q
R
FEE
D
P
V
R
M
L
R
T
L
R
F
A
A
K
LN---FK---I
D
P
A
I
L
D
I
F
D
V
E
M
T
--
Q
L
L
RDV
S
P
H
RL
Y
D
E
S
Q
K
L
F
T
M
G
H
L
A
R
V
L
P
M
L
I
A
F
G
V
W
K
Q
L
F
A
DIRP--------
D
L
T
--------
P
--------
F
I
Q
R
A
AKNTD
Q
R
I
Q---V-------------------GK-TI
N
-
P
A
F
F
Y
A
V
L
L
W
-
Q
P
F
L
E
R
C
D
-
F
Y
L
-SKGVV
P
A
E
A
R
A
Q
A
G
L
D
V
L
K
R
Q
A
T
R
T
V
I
P
R
F
A
E
T
F
I
R
E
V
W
E
M
Q
T
RLLNP
K
P
Q
Q
I
E
A
L
A
S
H
A
R
F
RAG
F
D
F
L
L
L
R
-EKSG-DD-
T
T
Q
G
M
G
S
W
W
E
A
Y
Q
E
MSN
D
E
K
E
A
A
I
S
Q
Y
N
R
Q
K
A
K
S
RRKVAAEPVESNKVDTEIEPLVDVPE
P
R
SRRG
K
K
E
R
A
R
Q
E
Q
S
I
D
R
F
I
E
K
SSAAQTNVMSDH
P
I
L
K
R
K
R
V
Q
R
D
L
S
Q
VIFGPTQ
23
PsiBlast_CBE
86.94
38%
-80
- C5 -
-
3AQL
1
?
B:
[11-411]
----------
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
--------
E
NGDSPMER
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
K
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
-
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
4
PsiBlast_PDB
86.81
38%
-73
- C5 -
-
3AQK
-
?
A:
[27-431]
----------
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---------------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
--------
E
NGDS
P
M
E
R
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
K
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
-
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
N
E
L
D
----------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.77
38%
-81
- C5 -
-
3AQN
1
?
B:
[11-411]
----------
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
--------
E
NGDSPMER
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
K
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
-
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
1
PsiBlast_PDB
86.61
38%
-84
- C5 -
-
3AQM
-
?
A:
[11-411]
----------
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
R
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
--------
E
NGDS
P
M
E
R
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
K
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
-
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
41
HHSearch
86.54
38%
-74
- C5 -
-
3AQK
-
?
A:
[19-430]
--
T
V
I
P
R
E
Q
H
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---------------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
-
P
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
ENGDS
P
M
E
R
--------
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
Y
P
L
L
E
T
A
Q
K
-
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
-
A
E
V
E
-
R
N
A
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
N
E
L
-----------------------------------------------------------------------------------------
42
HHSearch
86.30
38%
-87
- C5 -
-
3AQL
1
?
A:
[2-411]
-
V
T
V
I
P
R
E
Q
H
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
-
P
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
ENGDS
P
M
E
R
--------
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
Y
P
L
L
E
T
A
Q
K
-
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
-
A
E
V
E
-
R
N
A
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
2
PsiBlast_PDB
85.89
38%
-84
- C5 -
-
3AQL
1
?
A:
[11-411]
----------
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
--------
E
NGDS
P
M
E
R
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
K
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
-
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
3
PsiBlast_PDB
85.78
38%
-84
- C5 -
-
3AQN
1
?
A:
[11-411]
----------
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
--------
Y
F
T
--------
E
NGDS
P
M
E
R
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
K
I
A
Q
-
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
-
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
31
Fugue
84.72
39%
-4
- C5 -
-
3AQL
1
?
A:
[1-411]
Q
V
T
V
I
P
R
E
Q
H
A
I
S
R
K
D
I
S
E
N
A
L
K
V
M
Y
R
L
N
----
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
---
P
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
--
R
N
---
C
R
---
L
V
G
R
---
R
F
R
L
A
H
-----
V
M
F
G
----
P
---
E
I
I
E
V
A
T
F
R
---
G
-----------------
N
I
F
G
S
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
---
D
--------
F
T
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
G
---
M
R
---
I
S
P
E
T
A
E
P
I
P
-
R
L
A
--
T
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
H
L
F
Q
P
L
F
P
T
I
T
R
Y
FTENGDS
P
M
E
--------
R
--------
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
---
N
-------------------
D
M
-
R
V
N
-
P
A
F
L
F
A
A
M
F
W
-
Y
P
L
L
E
T
A
Q
-
K
I
A
Q
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
M
S
R
R
Q
G
K
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
-
A
E
V
E
R
N
A
-
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
--------------------------------------------------------------------------------------------
35
Fugue
61.63
22%
-30
- C5 -
-
4X4W
3
TRNT1_HUMAN
A:
[1-409]
-
M
F
T
M
K
L
Q
S
P
E
F
Q
S
-
L
F
T
E
G
L
K
S
L
T
E
L
F
V
----
K
E
N
----
H
E
L
R
I
A
G
G
A
V
R
D
L
L
N
G
V
K
---
P
Q
D
I
D
F
A
T
T
A
T
P
T
Q
M
K
E
M
F
-
Q
S
A
---
G
I
---
R
M
I
N
---
G
T
I
T
A
R
-----
L
H
------
E
---
E
N
F
E
I
T
T
L
-------
R
I
D
V
T
T
D
G
A
E
V
E
F
-
T
T
D
W
---
Q
K
D
A
E
R
R
D
L
T
I
N
S
M
F
L
G
F
D
------------
G
T
L
F
D
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
F
Y
G
R
I
V
---
D
K
PGD
H
D
P
E
T
L
E
A
I
A
E
N
A
K
--
G
L
A
G
-
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
H
V
N
H
L
I
H
L
I
Y
D
L
D
V
A
P
Y
I
G
L
P
A
N
A
--------
S
L
E
--------
E
--------
F
-
D
K
V
S
K
N
V
D
---------------------------
G
F
-
S
P
K
-
P
V
T
L
L
A
S
L
F
K
-
V
Q
----------------------------------------------
D
D
V
T
K
L
D
L
R
L
K
I
A
K
E
E
K
N
L
G
L
F
I
V
K
N
R
K
D
----
L
I
K
A
-
T
D
S
S
-
D
P
-
L
--------
K
P
Y
Q
D
F
I
I
D
S
D
-------
A
T
T
R
V
C
E
L
L
K
Y
Q
G
E
H
C
L
L
K
E
M
Q
Q
W
S
I
P
P
F
P
V
S
G
H
D
I
R
K
V
G
I
S
S
G
K
E
I
G
A
L
L
Q
Q
L
R
E
Q
W
K
K
S
G
Y
Q
M
E
K
D
E
L
L
S
Y
I
K
K
T
L
-----------
45
HHSearch
59.55
24%
-16
- C5 -
-
4X4W
2
TRNT1_HUMAN
A:
[13-313]
--------------
S
L
F
T
E
G
L
K
S
L
T
E
L
F
V
----
K
E
N
----
H
E
L
R
I
A
G
G
A
V
R
D
L
L
N
G
V
K
---
P
Q
D
I
D
F
A
T
T
A
T
P
T
Q
M
K
E
M
F
-
Q
S
A
G--
I
R
M
I
N---------
G
T
I
T
-----
A
R
L
H
----
E
---
E
N
F
E
I
T
T
L
R
---
I
D
V
T
T
-----
D
G
--
A
E
-
V
E
F
T
T
D
W
Q
K
D
A
E
R
R
D
L
T
I
N
S
M
F
L
G
F
D
------------
G
T
L
F
D
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
F
Y
G
R
I
V
DKP
G
D
---
H
D
P
E
T
L
E
A
I
-
A
E
N
A
--
K
G
L
A
G
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
H
V
N
H
L
I
H
L
I
Y
D
L
D
V
A
P
Y
I
G
L
P
A
N
A
--------
S
L
E
---------------------
E
F
D
K
V
S
K
N
V
----
D
-------------------
G
F
-
S
P
K
-
P
V
T
L
L
A
S
L
F
K
-
V
Q
D
D
--------------------------
V
T
K
L
D
L
R
L
K
I
A
K
E
E
K
N
L
G
L
F
I
V
K
N
R
K
D
L
I
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
58.90
24%
-23
- C5 -
-
4WBY
1
?
A:
[9-323]
----------------
I
E
E
I
A
R
E
V
G
Q
I
A
K
----
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
V
N
V
H
P
F
P
---
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
---
R
E
------------------
P
A
S
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
---
L
EDY-----
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
--
V
S
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
S
R
S
T
E
K
L
L
-
K
Q
A
V
N
L
G
L
L
K
E
A
P
R
G
R
L
I
N
E
I
K
L
A
L
R
E
D
R
F
L
E
I
L
E
L
Y
R
K
Y
R
V
L
E
E
I
I
E
G
F
Q
W
--------
N
E
K
V
L
------
Q
--------
K
L
Y
A
L
R
K
V
V
D
W
H
A
L
E
F
-
S
-------------------
E
E
-
R
I
D
Y
G
W
L
Y
L
L
I
L
I
S
-
N
L
D
Y
------------------------
E
R
G
K
H
F
L
E
E
M
S
A
P
S
W
V
R
E
T
Y
K
F
M
K
F
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
57.81
30%
-130
- C5 -
-
1MIV
-
CCA_GEOSE
A:
[9-220]
---------------------
L
G
I
I
Q
Q
L
K
----
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
---
I
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
K
T
---
I
D
---
V
G
S
K
---
H
G
T
V
V
V
-----
V
H
K
G
----
K
---
A
Y
-
E
V
T
T
F
K
---
T
D
G
-------
S
V
T
F
V
R
------
S
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
---
Y
--------
G
T
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
G
---
F
A
---
L
A
P
D
T
E
Q
A
I
-
V
Q
N
A
--
P
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
G
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
57.74
24%
13
- C5 -
-
5HC9
-
?
A:
[12-326]
-------------
V
E
R
V
D
P
K
I
L
N
L
F
R
L
L
G
----
K
F
G
D
E
V
N
M
P
V
Y
V
V
G
G
F
V
R
D
L
L
L
G
I
K
---
N
L
D
I
D
I
V
V
E
G
N
A
L
E
F
A
E
Y
A
-
K
R
F
L
P
G
K
L
---
V
K
H
D
---
K
F
M
T
A
S
-----
L
F
L
K
G---
G
---
L
R
I
D
I
A
T
A
R
---
L
E
Y
Y
E
----
S
P
A
K
L
-
P
-
D
V
E
M
S
T
I
K
K
D
L
Y
R
R
D
F
T
I
N
A
M
A
I
K
L
N
---
P
KDF-----
G
L
L
I
D
F
F
G
G
Y
R
D
L
K
E
G
V
I
R
V
L
H
T
--
L
S
F
V
D
D
P
T
R
I
L
R
A
I
R
F
E
Q
R
F
D
---
F
R
---
I
E
E
T
T
E
R
L
L
-
K
Q
A
V
E
E
G
Y
L
E
R
T
T
G
P
R
L
R
Q
E
L
E
K
I
L
E
E
K
N
P
L
K
S
I
R
R
M
A
Q
F
D
V
I
K
H
L
F
P
K
T
Y
Y
--------
T
P
S
M
D
------
E
--------
K
M
E
N
L
F
R
N
I
P
W
V
-------------------------
E
E
-
N
F
G
-
E
V
D
R
F
Y
A
V
L
H
-
V
F
L
E
F
Y
--------------------
D
D
E
S
W
K
E
V
R
D
R
Y
S
L
R
R
N
L
I
N
E
I
R
H
V
E
K
S
A
P
A
L
L
E
M
-----------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
57.30
24%
-44
- C5 -
-
1MIV
-
CCA_GEOSE
B:
[6-287]
------------------
Q
E
A
L
G
I
I
Q
Q
L
K
----
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
---
I
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
K
----
T
I
---
D
V
G
S
---
K
H
G
T
V
V
-----
V
V
H
K
----
G
---
K
A
Y
E
V
T
T
F
K
---
T
D
G
-------------S
V
T
F
V
R
S
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
E
----
Y
--------
G
T
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
G
---
F
A
---
L
A
P
D
T
E
Q
A
I
-
V
Q
N
A
--
P
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
G
L
N
A
Y
-
L
P
G
L
A
G
--------
K
E
K
-----------------
Q
--
L
R
L
A
A
A
Y
R
------
W
-------------------
P
W
-
L
A
A
-
R
E
E
R
W
A
L
L
C
H
-
A
L
G
V
Q
E
------------------------
S
R
P
F
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
A
I
L
T
A
------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
57.08
24%
-39
- C5 -
-
1MIW
1
CCA_GEOSE
A:
[6-287]
------------------
Q
E
A
L
G
I
I
Q
Q
L
K
----
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
---
I
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
K
----
T
I
---
D
V
G
S
---
K
H
G
T
V
V
-----
V
V
H
K
----
G
---
K
A
Y
E
V
T
T
F
K
---
T
D
G
-------------S
V
T
F
V
R
S
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
E
----
Y
--------
G
T
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
G
---
F
A
---
L
A
P
D
T
E
Q
A
I
-
V
Q
N
A
--
P
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
G
L
N
A
Y
-
L
P
G
L
A
G
--------
K
E
K
-----------------
Q
--
L
R
L
A
A
A
Y
R
------
W
-------------------
P
W
-
L
A
A
-
R
E
E
R
W
A
L
L
C
H
-
A
L
G
V
Q
E
------------------------
S
R
P
F
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
A
I
L
T
A
------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
56.88
30%
-127
- C5 -
-
1MIW
1
CCA_GEOSE
A:
[9-220]
---------------------
L
G
I
I
Q
Q
L
K
----
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
---
I
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
K
T
---
I
D
---
V
G
S
K
---
H
G
T
V
V
V
-----
V
H
K
G
----
K
---
A
Y
-
E
V
T
T
F
K
---
T
D
G
-------
S
V
T
F
V
R
------
S
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
---
Y
--------
G
T
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
G
---
F
A
---
L
A
P
D
T
E
Q
A
I
-
V
Q
N
A
--
P
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
G
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
56.84
30%
-123
- C5 -
-
1MIY
1
CCA_GEOSE
A:
[9-220]
---------------------
L
G
I
I
Q
Q
L
K
----
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
---
I
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
K
T
---
I
D
---
V
G
S
K
---
H
G
T
V
V
V
-----
V
H
K
G
----
K
---
A
Y
-
E
V
T
T
F
K
---
T
D
G
-------
S
V
T
F
V
R
------
S
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
---
Y
--------
G
T
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
G
---
F
A
---
L
A
P
D
T
E
Q
A
I
-
V
Q
N
A
--
P
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
G
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
55.28
29%
23
- C5 -
-
4X4W
2
TRNT1_HUMAN
A:
[6-263]
-----------
L
Q
S
P
E
F
Q
S
L
F
T
E
G
L
K
S
L
T
E
L
F
V
K
E
N
----
H
E
L
R
I
A
G
G
A
V
R
D
L
L
N
G
V
K
---
P
Q
D
I
D
F
A
T
T
A
T
P
T
Q
M
K
E
M
F
Q
S
A
G
---
I
R
---
M
I
N
---------
G
-----
T
I
T
A
----
R
L
HE
E
N
F
E
I
T
T
L
R
---
I
D
V
T
T
D
G
--
A
E
V
E
F
T
T
-
D
--
W
---
Q
K
D
A
E
R
R
D
L
T
I
N
S
M
F
L
-
G
F
---
D
--------
G
T
L
F
D
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
F
Y
G
R
I
V
---
D
K
PGD
H
D
P
E
T
L
E
A
I
-
A
E
N
A
--
K
G
L
A
G
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
H
V
N
H
L
I
H
L
I
Y
D
L
D
V
A
P
Y
I
G
L
P
A
N
A
--------
S
L
E
--------
E
--------
F
-
D
K
V
S
K
N
V
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
54.84
22%
-9
- C5 -
-
3WFO
-
?
A:
[5-380]
--
E
I
V
S
S
G
K
H
T
L
H
G
L
N
F
Y
L
S
Y
F
D
D
V
A
K
V
L
----
P
R
E
----
H
Y
C
F
I
V
G
G
W
V
R
D
R
I
L
G
E
P
VGY
N
I
D
V
D
F
L
T
T
A
D
P
V
E
L
A
K
N
F
-
A
K
-----
R
----
I
G
G
---
H
F
F
V
F
E
P
T
I
A
S
V
V
L
H
L
PP
Y
R
---
Y
R
F
D
F
S
P
L
K
---
G
K
----------------
D
L
E
K
A
L
I
E
D
L
K
E
R
D
F
T
A
N
A
I
A
V
N
L
D
---
D
V
L
SIGA
K
Q
T
I
V
Y
D
P
T
G
G
I
K
D
L
E
Q
G
L
L
R
P
V
S
I
--
E
N
L
K
R
D
P
V
R
V
L
R
G
F
R
I
A
I
E
K
N
---
L
Q
---
L
T
E
D
F
Y
E
F
V
-
K
E
D
P
--
R
I
V
L
K
S
A
V
E
R
I
T
H
E
L
F
K
I
M
K
E
K
T
A
H
K
V
I
R
E
L
Y
E
Y
G
V
L
E
A
I
I
P
E
I
G
R
--------
L
R
E
VKD-----
P
--------
L
D
E
H
T
L
K
T
L
E
Y
L
E
Q
V
I
E
D
RAKYLS
A
E
L
L
E
N
FGKKRVL
G
E
F
T
D
V
-
E
L
L
K
W
G
A
L
F
H
-
D
I
G
K
P
Q
T
F
---------
V
T
F
Y
E
H
D
K
V
G
A
Q
I
V
R
E
I
G
E
R
L
R
W
G
D
E
A
T
E
F
V
A
K
L
V
R
H
H
L
R
P
--------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
44.07
36%
-30
- C5 -
-
4WC1
1
?
A:
[10-173]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RE---------
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
44.01
36%
-23
- C5 -
-
4WC2
1
?
A:
[10-171]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET-------
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
44.00
36%
-25
- C5 -
-
4WC6
1
?
A:
[10-171]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET-------
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
43.99
36%
-34
- C5 -
-
4WC0
1
?
B:
[10-187]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
PFP
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RE---------
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
43.83
36%
-25
- C5 -
-
4WC5
1
?
A:
[10-171]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET-------
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
43.81
36%
-36
- C5 -
-
4WC1
1
?
B:
[10-187]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
PFP
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RE---------
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
43.78
36%
-34
- C5 -
-
1VFG
1
?
B:
[10-190]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
PFP
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET------
V
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
43.63
36%
-33
- C5 -
-
4WC0
1
?
A:
[10-173]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RE---------
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
43.40
36%
-23
- C5 -
-
4WC7
1
?
A:
[10-171]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET-------
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
43.24
36%
-25
- C5 -
-
4WC4
1
?
A:
[10-171]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET-------
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
43.09
36%
-33
- C5 -
-
1VFG
1
?
A:
[10-167]
-----------------------------------
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
---
V
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
---
H
G
---
V
N
V
H
P
F
P
E
F
G
T
A
H
-----
L
K
I
G
----
K
---
L
K
L
E
F
A
T
A
R
RET------
V
E
P
A
S
------------
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
V
N
LED
Y
--------
G
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
-
H
P
V
S
-
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
N
---
F
K
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------