@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKK8: (2017-10-27 )
MDKLLKIMQELREKCPWDQEQTSMSLTKYAIEEAYEVEAAIRQGDINEIRNELGDLLLQVVFQSQMFSEQGAFNFQDVVEAISEKLVRRHPHVFQADQFNNLIPEQVSELWKQIKQQEKQGKPQSRLDEIKHGPALSQAQEIQKNVAKVGFDFETVEDAYTKLEEELDEFKQALKNQNSDEIQDEFGDCLFSLVNVGRKLGISSESSLLSTIHKFRSRFAFIEEQAIKQQRTLEDMTLSEMDELWNQAKRQLKSGEKPHAIQHEILEK
Atome Classification :
(20 SA)
-------.........10.---..---....----.20........30........40...------------.---------....50........60........--------70........80........90........100.-----......110.......120-..-.....130..-..---------....140.......150.......160.......170--.......----------.--------.180.......190...-----....200.......210.......220........230.......240..-.....250.......260......----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------
M
D
K
L
L
K
I
M
Q
E
L
R
---
E
K---CPW
D
----
Q
E
Q
T
S
M
S
L
T
K
Y
A
I
E
E
A
Y
E
V
E
A
A
IRQG------------
D
---------
I
N
E
I
R
N
E
L
G
D
L
L
L
Q
V
V
F
Q
S
Q
M
FSE--------QGAF
N
F
Q
D
V
V
E
A
I
S
E
K
L
V
R
RHPHVF
Q
A
D
Q
F
NNL
I
-----
P
E
Q
V
S
E
L
W
K
Q
I
K
Q
Q
E
KQGK-
P
Q
-
S
R
L
D
E
I-KHG-PA---------
L
S
Q
A
Q
E
I
Q
K
N
V
A
K
VGFD
F
E
T
V
E
D
A
Y
T
K
L
E
E
E
L
D
E
F
----
K
Q
A
LKNQ----------
N
--------
S
D
E
I
Q
D
E
F
G
D
C
L
F
S
L
V
N
-----
V
G
R
KLGIS
S
E
S
S
L
L
S
T
I
H
K
F
R
S
R
F
A
-
F
I
E
E
Q
A
I
K
Q
QR
T
L
E
DM
T
L
S
E
M
D
E
L
-
W
N
Q
A
K
R
Q
LKSGEKP
H
A
I
Q
H
E
I
LEK----------------------------
10
Fugue
77.47
44%
60
- C1 -
-
3CRA
-
MAZG_ECOLI
A:
[2-260]
-----N
Q
I
D
R
L
L
T
I
M
Q
R
L
R
---
D
P
ENG
C
P
W
D
----
K
E
Q
T
F
A
T
I
A
P
Y
T
L
E
E
T
Y
E
V
L
D
A
I
A
R
E
------------
D
---------
F
D
D
L
R
G
E
L
G
D
L
L
F
Q
V
V
F
Y
A
Q
M
A
Q
E
--------
E
G
R
F
D
F
N
D
I
C
A
A
I
S
D
K
L
E
R
R
L
A
R
-----------------------
W
E
Q
I
K
T
E
E
R
A
Q
K
-
A
Q
H
S
A
L
D
D
I
-
P
R
S
L
P
A
---------
L
M
R
A
Q
K
I
Q
K
R
C
A
N
V
G
F
D
W
T
T
L
G
P
V
V
D
K
V
Y
E
E
I
D
E
V
----
M
Y
E
A
R
Q
A
VV--------
D
--------
Q
A
K
L
E
E
E
M
G
D
L
L
F
A
T
V
N
-----
L
A
R
H
L
G
T
K
A
E
I
A
L
Q
K
A
N
E
K
F
E
R
R
F
R
-
E
V
E
R
I
V
A
A
R
G
L
E
M
T
E
----
T
M
E
E
V
-
W
Q
Q
V
K
R
Q
E
--------------------------------------------
21
HHSearch
76.87
43%
19
- C1 -
-
3CRA
-
MAZG_ECOLI
B:
[4-261]
-------
I
D
R
L
L
T
I
M
Q
R
L
-----------
W
D
----
K
E
Q
T
F
A
T
I
A
P
Y
T
L
E
E
T
Y
E
V
L
D
A
I
A
R
E
------------
D
---------
F
D
D
L
R
G
E
L
G
D
L
L
F
Q
V
V
F
Y
A
Q
M
A
Q
E
--------
E
G
R
F
D
F
N
D
I
C
A
A
I
S
D
K
L
E
R
-------------------------------------
Q
K
A
Q
H
-
S
A
L
D
D
I
P
R
S
L
-
P
A
---------
L
M
R
A
Q
K
I
Q
K
R
C
A
N
V
G
F
D
W
T
T
L
G
P
V
V
D
K
V
Y
E
E
I
D
E
V
----
M
Y
E
A
R
Q
A
VV--------
D
--------
Q
A
K
L
E
E
E
M
G
D
L
L
F
A
T
V
N
-----
L
A
R
H
L
G
T
K
A
E
I
A
L
Q
K
A
N
E
K
F
E
R
R
F
R
-
E
V
E
R
I
V
A
A
R
G
L
E
M
T
G
V
D
L
E
T
M
E
E
V
-
W
Q
Q
V
K
R
Q
E
I
-------------------------------------------
20
HHSearch
73.39
43%
76
- C1 -
-
3CRA
-
MAZG_ECOLI
A:
[4-260]
-------
I
D
R
L
L
T
I
M
Q
R
L
R
DPE
N
G
---
C
P
W
D
----
K
E
Q
T
F
A
T
I
A
P
Y
T
L
E
E
T
Y
E
V
L
D
A
I
A
R
E
------------
D
---------
F
D
D
L
R
G
E
L
G
D
L
L
F
Q
V
V
F
Y
A
Q
M
A
Q
E
--------
E
G
R
F
D
F
N
D
I
C
A
A
I
S
D
K
L
E
R
R
-----------------------
L
A
R
W
E
Q
I
K
T
E
E
R
A
Q
K
A
Q
H
-
S
A
L
D
D
I
P
R
S
L
-
P
A
---------
L
M
R
A
Q
K
I
Q
K
R
C
A
N
V
G
F
D
W
T
T
L
G
P
V
V
D
K
V
Y
E
E
I
D
E
V
----
M
Y
E
A
R
Q
A
VV--------
D
--------
Q
A
K
L
E
E
E
M
G
D
L
L
F
A
T
V
N
-----
L
A
R
H
L
G
T
K
A
E
I
A
L
Q
K
A
N
E
K
F
E
R
R
F
R
-
E
V
E
R
I
V
A
A
R
G
L
E
M
T
----
E
T
M
E
E
V
-
W
Q
Q
V
K
R
Q
E
--------------------------------------------
2
PsiBlast_PDB
73.17
43%
25
- C1 -
-
3CRC
1
MAZG_ECOLI
A:
[6-261]
-------
I
D
R
L
L
T
I
M
Q
R
L
R
---
D
P
ENG
C
P
W
D
----
K
E
Q
T
F
A
T
I
A
P
Y
T
L
E
E
T
Y
E
V
L
D
A
I
A
R
E
------------
D
---------
F
D
D
L
R
G
E
L
G
D
L
L
F
Q
V
V
F
Y
A
Q
M
A
Q
E
--------
E
G
R
F
D
F
N
D
I
C
A
A
I
S
D
K
L
E
R
R
H
P
----------------------------------------
S
A
L
D
D
I
-
P
R
S
L
P
A
---------
L
M
R
A
Q
K
I
Q
K
R
C
A
N
V
G
F
D
W
T
T
L
G
P
V
V
D
K
V
Y
E
E
I
D
E
V
M
Y
E
A
R
Q
A
V
V
D
Q
----------
A
----------
K
L
E
E
E
M
G
D
L
L
F
A
T
V
N
-----
L
A
R
H
L
G
T
K
A
E
I
A
L
Q
K
A
N
E
K
F
E
R
R
F
R
-
E
V
E
R
I
V
A
A
R
G
L
E
M
T
--
D
L
E
T
M
E
E
V
-
W
Q
Q
V
A
R
Q
---------------------------------------------
1
PsiBlast_PDB
71.06
43%
78
- C1 -
-
3CRA
-
MAZG_ECOLI
A:
[4-259]
-------
I
D
R
L
L
T
I
M
Q
R
L
R
---
D
P
ENG
C
P
W
D
----
K
E
Q
T
F
A
T
I
A
P
Y
T
L
E
E
T
Y
E
V
L
D
A
I
A
R
E
------------
D
---------
F
D
D
L
R
G
E
L
G
D
L
L
F
Q
V
V
F
Y
A
Q
M
A
Q
E
--------
E
G
R
F
D
F
N
D
I
C
A
A
I
S
D
K
L
E
R
R
-----------------------
L
A
R
W
E
Q
I
K
T
E
E
R
A
Q
K
-
A
Q
H
S
A
L
D
D
I
-
P
R
S
L
P
A
---------
L
M
R
A
Q
K
I
Q
K
R
C
A
N
V
G
F
D
W
T
T
L
G
P
V
V
D
K
V
Y
E
E
I
D
E
V
M
Y
E
A
R
Q
A
V
V
D
Q
----------
A
----------
K
L
E
E
E
M
G
D
L
L
F
A
T
V
N
-----
L
A
R
H
L
G
T
K
A
E
I
A
L
Q
K
A
N
E
K
F
E
R
R
F
R
-
E
V
E
R
I
V
A
A
R
G
L
E
M
T
----
E
T
M
E
E
V
-
W
Q
Q
V
K
R
Q
---------------------------------------------
9
PsiBlast_CBE
67.96
43%
48
- C1 -
-
3CRC
1
MAZG_ECOLI
B:
[6-261]
-------
I
D
R
L
L
T
I
M
Q
R
L
-----------
W
D
----
K
E
Q
T
F
A
T
I
A
P
Y
T
L
E
E
T
Y
E
V
L
D
A
I
A
R
E
------------
D
---------
F
D
D
L
R
G
E
L
G
D
L
L
F
Q
V
V
F
Y
A
Q
M
A
Q
E
--------
E
G
R
F
D
F
N
D
I
C
A
A
I
S
D
K
L
E
R
----------------------------------------
A
Q
H
S
A
L
D
D
I
-
P
R
S
L
P
A
---------
L
M
R
A
Q
K
I
Q
K
R
C
A
N
V
G
F
D
W
T
T
L
G
P
V
V
D
K
V
Y
E
E
I
D
E
V
M
Y
E
A
R
Q
A
V
V
D
Q
----------
A
----------
K
L
E
E
E
M
G
D
L
L
F
A
T
V
N
-----
L
A
R
H
L
G
T
K
A
E
I
A
L
Q
K
A
N
E
K
F
E
R
R
F
R
-
E
V
E
R
I
V
A
A
R
G
L
E
M
T
G
V
D
L
E
T
M
E
E
V
-
W
Q
Q
V
A
R
Q
---------------------------------------------
22
HHSearch
51.36
23%
-83
- C1 -
-
2YXH
-
?
A:
[2-114]
-------
V
E
R
L
L
E
I
I
E
R
S
L
---
R
K
---
C
P
W
L
----
E
K
Q
S
I
E
T
L
L
E
A
L
A
S
E
I
E
E
V
A
E
A
V
K
K
N
------------
D
---------
L
A
N
L
E
E
E
I
G
D
M
I
Y
D
A
L
L
V
A
A
V
A
Q
R
--------
D
Y
G
I
D
L
E
S
A
I
Q
K
V
V
E
K
I
S
H
R
K
P
W
L
F
W
E
E
K
---
I
S
-----
L
E
E
A
E
K
I
W
K
E
R
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
50.54
22%
-78
- C1 -
-
2YXH
-
?
A:
[2-114]
-------
V
E
R
L
L
E
I
I
E
R
S
L
---
R
K
---
C
P
W
L
----
E
K
Q
S
I
E
T
L
L
E
A
L
A
S
E
I
E
E
V
A
E
A
V
K
K
N
------------
D
---------
L
A
N
L
E
E
E
I
G
D
M
I
Y
D
A
L
L
V
A
A
V
A
Q
R
--------
D
Y
G
I
D
L
E
S
A
I
Q
K
V
V
E
K
I
S
H
R
K
P
W
L
F
W
E
E
K
I
S
--------
L
E
E
A
E
K
I
W
K
E
R
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
47.44
23%
36
- C1 -
-
5TK8
1
?
A:
[2-192]
--------
S
S
L
L
D
I
I
Y
Q
L
R
---
Q
V
---
P
R
W
D
GSFQ
F
E
K
E
D
V
S
Q
H
S
F
S
V
I
A
I
S
H
I
L
C
E
L
K
E
T
------------
L
---------
E
G
K
-
K
I
N
K
E
K
L
L
L
Y
A
L
Y
H
---------------------
D
V
T
E
V
V
S
-------
T
H
I
I
S
P
V
K
K
N
S
I
L
-----
K
D
P
F
N
A
F
R
E
Q
I
K
N
S
L
F
D
N
L
-
P
I
-
T
L
S
D
T
L
-
S
T
--
I
L
---------
N
N
N
D
L
E
I
Q
E
I
V
E
H
A
D
H
-----
V
D
A
Y
C
K
S
C
I
E
V
H
R
---------
G
N
K
----------
D
--------
F
I
S
I
Q
R
S
L
G
D
K
L
D
N
L
T
K
-----
E
------------
Y
P
Y
L
K
E
F
Q
N
L
F
--------------
L
K
D
F
P
L
E
N
K
N
Y
R
-
Y
---------------------------------------------------
27
HHSearch
46.91
24%
-33
- C1 -
-
4QGP
1
?
A:
[15-112]
---------
E
L
L
D
I
L
R
E
F
R
---
D
S
---
R
G
W
L
----
K
Y
H
T
P
K
N
L
A
V
S
I
S
I
E
V
A
E
L
L
E
I
F
Q
W
T
RS
S
D
E
E
F
E
V
L
E
R
R
---------
K
G
E
V
E
E
E
I
A
D
V
L
I
Y
L
L
F
L
C
D
V
------------
A
E
I
N
P
I
E
A
V
K
R
K
M
E
K
N
E
R
K
Y
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
46.48
24%
-37
- C1 -
-
4QGP
1
?
B:
[15-112]
---------
E
L
L
D
I
L
R
E
F
R
---
D
S
---
R
G
W
L
----
K
Y
H
T
P
K
N
L
A
V
S
I
S
I
E
V
A
E
L
L
E
I
F
Q
W
T
RS
S
D
E
E
F
E
V
L
E
R
R
---------
K
G
E
V
E
E
E
I
A
D
V
L
I
Y
L
L
F
L
C
D
V
------------
A
E
I
N
P
I
E
A
V
K
R
K
M
E
K
N
E
R
K
Y
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
44.94
18%
-22
- C1 -
-
5IE9
-
?
A:
[1-103]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-
E
A
K
-
T
M
---------
K
D
M
Q
K
E
V
D
A
Y
I
G
Q
F
K
E
G
Y
F
S
P
L
A
M
M
A
R
L
T
E
E
M
G
E
L
----
A
R
E
V
N
H
Y
Y---------
G
--------
E
R
S
I
E
E
E
L
G
D
V
L
F
V
M
I
C
-----
M
A
N
S
L
N
I
D
L
E
T
A
H
N
I
V
M
N
K
F
N
T
R
D
K
-
D
R
---------------------------------------------------------------------------
4
PsiBlast_PDB
43.98
36%
5
- C1 -
-
1VMG
1
?
A:
[40-89]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
F
T
W
L
V
E
E
V
G
E
L
----
A
E
A
L
L
S
N
----------
N
--------
L
D
S
I
Q
E
E
L
A
D
V
I
A
W
T
V
S
-----
I
A
N
L
E
G
I
D
I
E
E
A
L
------------------------------------------------------------------------------------------
15
Fugue
42.62
12%
15
- C1 -
-
5EYB
-
REB1_SCHPO
A:
[12-358]
ARWT
A
E
H
W
D
Y
L
E
R
R
M
Q
N
F
C
---
Q
T
---
Y
S
L
D
----
H
T
Q
V
A
D
S
L
H
E
K
R
L
H
G
P
L
S
S
L
V
K
L
L
V
Q
------------
E
---------
M
P
S
F
T
R
R
T
I
L
R
H
L
R
A
L
Y
N
I
P
G
Y
E
K
YSRKNSSG
R
G
D
F
G
V
Q
E
T
A
I
I
S
Q
E
V
H
N
F
I
M
D
Q
G
W
S
E
Y
Q
F
C
N
Q
I
W
AGKC
P
K
T
I
R
M
F
Y
S
N
L
Y
K
K
L
S
H
R
D
-
A
K
-
S
I
Y
H
H
V
-
R
R
A
-
Y
N
PFEDRCVWS
K
E
E
D
E
E
L
R
K
N
V
V
E
H
G
K
C
W
T
K
I
G
R
K
M
A
R
M
P
N
D
C
R
D
R
----
W
R
D
V
V
R
F
----------
G
DKLKRNAW
S
L
E
E
E
T
Q
L
L
Q
I
V
A
E
L
S
D
IN
W
T
L
V
A
Q
M
L
G
T
R
T
R
L
Q
C
R
Y
K
F
Q
Q
L
T
K
A
A
S
K
F
E
L
Q
E
N
V
W
L
L
E
R
I
Y
D
S
L
L
N
N
G
G
K
I
H
W
E
N
I
V
K
E
A
N
G
R
W
T
R
D
Q
M
L
F
Q
F
I
N
L
K
K
M
IPSYDNLP
L
L
E
A
T
K
S
A
I
D
D
F
K
V
V
LS
32
HHSearch
42.04
14%
-81
- C1 -
-
1VMG
1
?
A:
[19-93]
------------
E
L
Q
S
K
M
K
E
--
M
Y
---
F
E
K
D
----
S
Q
R
G
I
Y
A
T
F
T
W
L
V
E
E
V
G
E
L
A
E
A
L
L
S
N
------------
N
---------
L
D
S
I
Q
E
E
L
A
D
V
I
A
W
T
V
S
I
A
N
L
------------
E
G
I
D
I
E
E
A
L
K
K
K
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
41.59
20%
-15
* C1 *
-
5IE9
-
?
D:
[13-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
A
Y
I
G
Q
F
K
E
G
Y
F
S
P
L
A
M
M
A
R
L
T
E
E
M
G
E
L
----
A
R
E
V
N
H
Y
YG-------------------
S
I
E
E
E
L
G
D
V
L
F
V
M
I
C
-----
M
A
N
S
L
N
I
D
L
E
T
A
H
N
I
V
M
N
K
F
N
T
R
D
K
-
D
----------------------------------------------------------------------------
41
HHSearch
39.99
24%
26
- C1 -
-
2GTA
-
YPJD_BACSU
A:
[12-98]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
D
R
Y
I
G
Q
F
K
E
G
Y
F
S
P
L
A
M
M
A
R
L
T
E
E
L
G
E
L
----
A
R
E
V
N
H
R
Y
GEKPKKATE
D
--------
D
K
S
M
E
E
E
I
G
D
V
L
F
V
L
V
C
-----
L
A
N
S
L
D
I
S
L
E
E
A
H
D
R
V
M
H
K
F
N
T
---------------------------------------------------------------------------------
34
HHSearch
39.47
20%
15
- C1 -
-
5IE9
-
?
C:
[13-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
A
Y
I
G
Q
F
K
E
G
Y
F
S
P
L
A
M
M
A
R
L
T
E
E
M
G
E
L
----
A
R
E
V
N
H
Y
Y
GE----------------
E
R
S
I
E
E
E
L
G
D
V
L
F
V
M
I
C
-----
M
A
N
S
L
N
I
D
L
E
T
A
H
N
I
V
M
N
K
F
N
T
R
D
K
-
D
----------------------------------------------------------------------------
28
HHSearch
38.26
15%
18
- C1 -
-
2Q5Z
1
?
B:
[21-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
L
S
E
L
Q
S
H
I
K
E
F
D
Y
A
P
E
Q
S
E
H
Y
F
F
K
L
I
E
E
V
G
E
L
----
S
E
S
I
R
K
G
KSGQPTLDE-
L
--------
K
G
S
V
A
E
E
L
Y
D
V
L
Y
Y
V
C
A
-----
L
A
N
I
H
G
V
N
L
E
K
T
R
E
L
K
E
V
L
N
K
V
K
Y
N
-
R
----------------------------------------------------------------------------
35
HHSearch
37.66
19%
-74
- C1 -
-
2Q73
-
?
C:
[6-91]
-------------
L
Q
S
H
I
K
E--
F
D
---
Y
A
P
E
-------
Q
S
E
H
Y
F
F
K
L
I
E
E
V
G
E
L
S
E
S
I
R
K
G
------------
K
SGQPTLDEL
K
G
S
V
A
E
E
L
Y
D
V
L
Y
Y
V
C
A
L
A
N
I
------------
H
G
V
N
L
E
K
T
H
E
L
K
E
V
L
N
K
V
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------