@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKL2: (2017-10-27 )
MVTVREQLPEQLTELSEETTVEHAAETQVGLASWLDRVREILDGAELKQLEEVAHLTLQKELDSTVNHRSNTFATGVGMADILAHLHVDEDTLSAAMLYRSVREDITDIEEVKRKFGEQVYNLVKGTLAMGKLSELIEKNKRLEDHFNNNQREHLSGIYKMLISVTEDVRVVLIKLAERTYSLRELANSSRERQERVAREILTIYSPLAHRLGIAQLKWELEDLAFRYLAPDRYKEIASLLNEKRLEREHYIQFVIDRLKSELAAHGIEAEITGRAKHIYSIYRKMKSKNLSFDQLYDIRALRVLVNSVPECYHSLGIVHQIWRHIPHQFDDYITNPKANGYRSLHTAVIAENKSLEVQIRTHEMHDEAELGVCSHFNYKEGSKNTDHSFNHRLHSLRAVLEHYQERNETTVHQNEDETEGFDQLQDFEGFEKIYVFSRDGDIKELPRGSTVLDFAYHVHTEVGNKCYAARVNQRYVPLTYTLKTGEQVEILTKKDREPNRDWLVNSLGYIKTARARDKLRHWFRQQDRSKNLEVGRELLNKELSRLAIHPKSIDLNDYSSHFNVKTGDDILVSLVSGDISLHALINQINRQMHLDQDEPELVLKPTLNPRASHTLSAHGILIDGLDNVELHIAQCCQPVHGESIAGYITLNRGVSIHKVLCSDYQRMIKQEPERAVEADWEMQPTRGQSVQIVVEAYDRRGLLKDLTQVIFSDQINIRQVNTISEADGIANMKLLIEVKGLAQLSRLLARLEQQPGIISARRMIQGV
Atome Classification :
(20 SA)
--------------------------.........10-----------........20........30........40........50........60--------....-..--...70.......-----.80...-...--..90...--.....100.......110....-----...120.......130..----.....140.......150---.........160.......170.----......180.......190----....--------------------------------------------..---.200-----.......210.......220..-.......230.......240------.......------------.250..-----------.....260...-----....270....-...280.......290----.....-..300.......310.......320....--...--330.....--..340....------...-350------.-------.......360.......370..-.....380.......390...----....400.......410.......420...-...---.430......-.440-----------........450.......460....-...470--.......480.-......490.......500....-------...510.......520.......530.......540------.........550.---------......560.........570....---...580.......590.......600----........-------------610.......620--.......630.......640.......650.......660.......670.......680.......690.......700---------------..-.......710.......720.......-----------730--------------------....-...740.......-750......---.760......------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------MV
T
V
R
E
Q
L
P
E
Q
-----------
L
T
E
L
S
E
E
T
T
V
E
H
A
A
E
TQ
V
G
L
A
S
W
L
D
R
V
R
E
I
L
D
G
A
E
L
K
Q
L
E
E
V
A
H
L
T
L
Q
K
---------
E
L
D
S
-
T
V--NHRSNTFATGV
G
-----
M
A
D
I
L
A
-
H
LH--V
D
E
D
T
L
S
--
A
A
M
L
Y
R
S
V
R
E
D
I
T
D
I
E
E
V
K
R
K
F
-----
G
E
Q
V
Y
N
L
V
K
G
T
L
A
M
G
K
L
S
----
E
L
I
E
K
N
K
R
L
E
D
HFNN
N
-----
Q
R
E
H
L
S
G
I
Y
K
M
L
I
S
VTE
D
V
R
V
V
L
----
I
K
L
A
E
R
T
Y
S
L
R
E
L
A
N
S
S
R
E
----
R
Q
E
R
--------------------------------------------
V
A
---
R
E
I
L
-----
T
I
Y
S
P
L
A
H
RL
G
I
A
Q
L
K
W
E
--
L
E
-
D
L
A
F
R
YLA
P
D
R
Y
K
E
I
A
S
L
L
-------
N
E
K
R
L
E
R
------------
E
H
Y
I
Q
F
-----------
V
I
D
R
L
K
S
E
L
A
A-----HGI
E
A
E
ITG
R
A
-
K
H
I
Y
S
I
Y
R
K
M
K
SKNL
S
----
F
D
Q
L
Y
-
D
I
R
A
L
R
V
L
V
N
S
V
P
E
C
Y
H
S
L
G
I
V
H
Q
I
W
R
HI--
P
H
Q
--
F
D
D
YITNP--KANGY
R
S
L
H
------
T
A
V
-
I
A-------E-------N
K
S
L
E
V
Q
I
R
THEMHDEAE
L
G
V
C-SHFNYKEGSKNTD
H
S
F
N
H
R
L
H
----
S
L
R
A
V
L
E
H
Y
Q
ERNETTVHQNEDET
E
G
F
D
Q
L
-
Q
D
F---EGF
E
K
I
Y
V
F
S-RDG------------
D
I
K
ELPRGS
T
V
L
D
F
A
Y
H
V
HTEVGN
K
-
C
Y
A
ARV--NQ
R
Y
V
P
L
T
Y
T
L-KTG
E
Q
V
E
I
L
TKKDREP
N
R
D
W
L
V
N
-------SLG
Y
I
K
T
A
R
A
R
D
K
L
R
H
W
F
R
Q
QDRSK
N
L
E
V
G
R
E
L
L
--------
N
K
E
L
S
R
LAIHPKS---------IDLNDYS--SHFNVKTG
D
D
I
L
V
S
L
V---SG
D
I
S
L
H
A
L
I
N
Q
I
N
R
QMHLDQDEP
E
-----
L
V
L
KPTLN-------------PRASHTLSAH
G
I
L
--
I
DGLDN
V
E
L
H
I
A
Q
CCQPVHGES
I
A
G
Y
I
T
LNRGV
S
I
H
K
V
L
C
S
D
Y
Q
R
M
I
K
QE
P
E
R
A
VEADWEMQPTRG
Q
S
V
Q
I
V
V
E
A
Y
D
R-----------------R
G
-
L
L
K
D
L
T
Q
V
I
F
SDQI
N
I
R
Q
V
NTISEADG-----------IA
N
--------------------
M
K
L
L
-
I
E
V
K
G
L
A
Q
L
S
R
L
L
-
A
R
L
EQQP
G
I
---
I
S
A
R
R
M
IQGV------
40
Fugue
89.26
36%
-121
- C5 -
-
1VJ7
1
RELA_STREQ
A:
[5-371]
---------------------------------------------------------------
I
N
L
T
G
E
E
V
V
A
L
A
A
K
Y
M
N
E
T
D
A
A
F
V
K
K
A
L
D
Y
A
T
A
A
---------
H
F
Y
Q
-
V
R
--
K
S
G
E
P
Y
I
V
H
P
I
Q
-----
V
A
G
I
L
A
-
D
L
H
--
L
D
A
V
T
V
A
--
C
G
F
L
H
D
V
V
E
D
T
D
I
T
L
D
N
I
E
F
D
F
-----
G
K
D
V
R
D
I
V
D
G
V
T
K
L
G
H
-----------------------------------
R
K
M
L
M
A
M
S
K
D
I
R
V
I
L
----
V
K
L
A
D
R
L
H
N
M
R
T
L
----------
K
Q
E
R
--------------------------------------------
I
S
---
R
E
T
M
-----
E
I
Y
A
P
L
A
H
R
L
G
I
S
R
I
K
W
E
--
L
E
-
D
L
A
F
R
Y
L
N
E
T
E
F
Y
K
I
S
H
M
M
-------
N
E
K
R
R
E
R
------------
E
A
L
V
D
D
-----------
I
V
T
K
I
K
S
Y
T
T
E
-----
Q
G
L
F
G
D
V
Y
G
R
P
-
K
H
I
Y
S
I
Y
R
K
M
R
D
K
K
K
R
----
F
D
Q
I
F
-
D
L
I
A
I
R
C
V
M
E
T
Q
S
D
V
Y
A
M
V
G
Y
I
H
E
L
W
R
P
M
--
P
G
R
--
F
K
D
Y
I
A
A
P
--
K
A
N
G
Y
Q
S
I
H
------
T
T
V
-
Y
G
-------
P
-------
K
G
P
I
E
I
Q
I
R
T
K
E
M
H
Q
V
A
E
Y
G
V
A
-
A
N
W
I
K
E
L
V
E
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
84.45
34%
-22
- C5 -
-
1VJ7
1
RELA_STREQ
A:
[5-371]
---------------------------------------------------------------
I
N
L
T
G
E
E
V
V
A
L
A
A
K
Y
M
N
E
T
D
A
A
F
V
K
K
A
L
D
Y
A
T
A
A
---------
H
F
Y
Q
V
R
K
--
S
-
G
E
P
Y
I
V
H
P
I
Q
-----
V
A
G
I
L
A
-
D
L
H
--
L
D
A
V
T
V
A
--
C
G
F
L
H
D
V
V
E
D
T
D
I
T
L
D
N
I
E
F
D
F
-----
G
K
D
V
R
D
I
V
D
G
V
T
K
L
G
-----------------------------------
H
R
K
M
L
M
A
M
S
K
D
I
R
V
I
L
----
V
K
L
A
D
R
L
H
N
M
R
T
L
K
----------
Q
E
R
--------------------------------------------
I
S
---
R
E
T
M
-----
E
I
Y
A
P
L
A
H
R
L
G
I
S
R
I
K
W
E
--
L
E
-
D
L
A
F
R
Y
L
N
E
T
E
F
Y
K
I
S
H
M
M
-------
N
E
K
R
R
E
R
------------
E
A
L
V
D
D
-----------
I
V
T
K
I
K
S
Y
T
T
E
-----
Q
G
L
F
G
D
V
Y
G
R
P
-
K
H
I
Y
S
I
Y
R
K
M
R
D
K
K
K
R
----
F
D
Q
I
F
-
D
L
I
A
I
R
C
V
M
E
T
Q
S
D
V
Y
A
M
V
G
Y
I
H
E
L
W
R
P
M
--
P
G
R
--
F
K
D
Y
I
A
A
P
--
K
A
N
G
Y
Q
S
I
H
------
T
T
V
Y
G
P
-------
K
-------
G
-
P
I
E
I
Q
I
R
T
K
E
M
H
Q
V
A
E
Y
G
V
A
-
A
-------------------
N
----
W
I
K
E
L
V
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
55.54
18%
23
- C3 -
-
5MZ6
-
?
?:
[12-1140]
HI
E
K
L
D
E
L
R
K
N
V
S
C
T
V
I
G
F
A
E
Q
T
A
E
L
Q
Q
E
I
S
E
L
F
I
A
E
FGVN
G
P
I
D
MNS
L
S
K
L
A
R
I
T
S
Y
Y
A
S
S
E
Y
F
Q
G
L
A
K
Y
Q
R
T
A
C
K
M
F
I
T
W
Q
T
L
R
K
E
A
M
E
C
R
S
K
D
R
---------
E
I
F
A
-
S
I
--
P
A
K
L
C
F
F
Y
F
Y
N
G
E
L
C
R
A
V
V
C
L
L
D
-
Y
I
D
--
L
S
D
D
T
L
A
K
E
A
A
L
R
W
L
M
F
L
G
E
T
E
L
I
E
K
K
L
K
T
W
K
M
D
KS
S
K
D
M
F
S
A
T
E
F
A
M
N
Y
L
K
K
S
EY
R
V
E
M
L
E
K
L
M
K
L
R
D
K
V
K
S
D
PTRS
F
S
R
Y
E
L
A
S
Y
V
S
W
L
C
S
T
L
S
N
V
P
V
G
S
ALRE
C
E
F
P
D
R
V
S
H
I
Q
E
A
A
L
K
S
D
S
----
L
V
R
N
R
IPGLASSQFDNSVNASIWPFLDGHQED
S
N
Y
Y
V
H
I
G
S
T
I
A
W
H
F
E
M
R
---
R
E
C
A
L
V
N
V
T
T
A
Q
T
R
D
S
M
S
A
M
I
L
N
L
R
V
A
--
L
K
S
A
S
F
F
R
V
L
Q
T
T
N
T
L
A
Y
Y
S
S
I
I
EEAGS
E
K
N
A
K
L
M
R
------------
V
S
C
V
N
L
L
SSNPIV
C
N
V
C
T
I
Y
P
L
H
S
S
F
A
A
E
Y
M
M
S
Y
A
I
H
S
D
F
S
Q
L
S
I
K
H
F
N
D
E
F
A
R
I
R
E
R
G
M
S
----
S
Q
V
L
M
H
R
D
S
S
V
R
P
R
P
N
I
I
Q
N
E
I
F
G
M
C
V
I
R
W
L
T
K
K
L
--
D
S
K
ES
A
D
E
D
T
M
E
I
--
F
N
N
A
L
K
I
V
R
YLQQRT
T
D
M
-
I
L
-------
A
-------
V
T
Q
L
G
R
Q
L
E
F
P
M
E
C
N
Y
S
W
M
R
P
T
I
D
K
E
R
F
E
K
V
R
L
A
M
R
N
E
M
N
H
Y
G
H
ILY
R
E
W
R
C
R
L
F
A
Y
V
G
R
T
S
R
D
P
W
E
A
A
Y
A
W
A
E
S
T
Q
I
-
G
A
R
---
N
A
V
Q
S
R
L
E
K
C
-
K
R
G
LVTMSG
H
D
R
F
K
T
C
V
Q
S
M
P
D
E
M
T
L
V
Q
I
A
M
A
D
----
D
K
T
-
I
Y
L
V
K
L
--
H
A
D
R
D
P
I
I
M
P
L
A
H
Y
S
Q
A
V
E
L
M
D
K
F
T
F
L
L
D
E
D
E
M
I
A
K
Y
PGDIT
P
E
E
F
W
K
R
R
K
I
V
D
G
R
M
M
T
F
V
D
E
V
Q
K
H
F
L
G
V
A
A
S
L
L
MPSGQLG
P
K
A
A
E
L
A
I
K
I
H
K
L
S
K
GGLL
L
G
E
A
K
E
M
V
Y
Q
S
--
K
L
M
D
A
K
S
W
E
A
L
I
L
R
F
C
E
M
R
T
T
D
E
K
F
K
S
F
L
P
L
M
H
R
N
S
V
E
V
M
N
Q
D
E
K
K
Y
T
Y
L
V
I
C
P
H
L
S
QFCWERLPIFDEY
P
Y
V
G
R
Q
V
S
I
H
S
T
F
S
Q
L
E
A
M
K
S
Q
E
K
Q
I
-----
P
L
Q
I
D
V
Q
N
A
Y
Y
I
L
D
P
D
----
N
N
L
G
E
T
Q
K
R
M
V
E
Y
I
N
K
F
----
N
W
E
G
T
V
G
S
A
P
K
S
N
E
I
S
A
A
L
S
Q
RD
A
F
F
F
IGHGSGSSVMP
R
S
-
V
L
K
Q
S
T
C
N
A
I
S
L
L
M
G
C
G
S
V
R
T
I
P
Q
A
L
G
FDGKTA
I
L
D
Y
A
M
A
K
CP
L
I
V
G
C
LWTVT
D
G
E
I
D
R
F
L
I
R
M
I
-
D
D
C
F
E
L
R
Q
L
S
E
A
M
-
H
E
A
R
S
K
A
R
L
KYL
T
G
A
A
V
V
M
Y
G
L
P
V
V
A
K
Q
45
Fugue
50.67
17%
16
- C4 -
-
4BS9
-
?
A:
[3-781]
------------------PTALQIKP
H
F
H
V
E
I
I
E
P
K
Q
-----------
V
Y
L
L
G
E
Q
G
N
H
A
L
T
G
Q
L
Y
C
Q
I
L
P
F
L
N
G
--------------
E
Y
T
R
E
Q
I
V
E
---------
K
L
D
G
-
Q
V
--
P
E
E
Y
I
D
F
V
L
S
R
L
-----
V
E
K
G
Y
L
-
T
E
V
--
A
P
E
L
S
L
E
--
V
A
A
F
W
S
E
L
G
I
A
P
S
V
V
A
E
G
L
K
Q
------------
P
V
T
V
T
T
A
G
K
G
I
R
----
E
G
I
V
A
N
--
L
A
A
A
L
E
E
A
-----
G
I
Q
V
S
D
P
T
A
Q
L
Q
V
V
L
T
D
D
----------------
Y
L
Q
P
E
L
A
A
I
N
K
E
----
A
L
E
R
--------------------------------------------
Q
Q
---
P
W
L
L
-----
V
K
P
V
G
S
I
L
W
L
G
P
L
F
V
P
G
E
TG
C
W
-
H
C
L
A
Q
R
L
Q
G
N
R
E
V
E
A
S
V
L
Q
-------
Q
K
R
A
L
Q
E
RP
T
A
R
A
T
L
P
S
T
L
Q
T
G
L
Q
W
-----------
A
A
T
E
I
A
K
W
M
V
K
-----
R
H
L
N
A
I
A
P
G
T
A
-
R
-----
F
P
T
L
A
G
K
I
F
T
----
F
N
Q
-
T
-
T
L
E
L
K
A
H
P
L
S
R
R
P
Q
C
-
P
T
C
G
D
R
E
T
L
Q
R
R
G
F
E
P
L
K
--
L
E
S
R
P
K
H
P
E
Q
T
V
Q
K
Y
Q
H
L
I
------
G
P
I
-
T
G
-------
V
-------
V
T
E
L
-
V
R
S
R
A
S
G
L
C
E
A
I
E
R
Y
S
G
-
I
F
Q
G
D
E
P
R
K
R
A
T
L
A
E
L
G
D
L
A
I
----
H
P
E
Q
C
L
H
F
S
D
R
Q
Y
D
N
R
E
S
S
N
E
R
A
T
V
T
H
D
W
I
P
Q
R
F
DAS
K
A
H
D
W
T
P
V
W
S
L
T
E
Q
------------
T
H
K
Y
L
P
--
T
A
L
C
Y
Y
R
Y
P
F
P
P
E
--------------
H
R
F
C
R
---
S
D
-
S
N
G
N
A
A
G
---------
N
T
L
E
E
A
I
-------
L
Q
G
F
M
E
L
V
E
-
R
D
S
V
C
L
W
W
Y
N
R
------------------------
V
S
R
P
A
V
D
L
S
S
---------
F
D
E
P
Y
F
L
Q
L
Q
Q
F
Y
Q
T
Q
N
R
D
L
W
V
L
D
L
---
T
A
D
L
G
I
P
A
F
V
G
V
S
N
R
K
A
G
-
S
S
E
R
I
I
-----
L
G
F
G
A
H
L
D
-------------
P
T
V
A
I
L
R
A
L
T
E
V
N
--
Q
I
G
L
E
L
D
A
T
D
W
L
V
N
------
A
T
L
A
A
S
P
Y
L
V
A
D
A
S
Q
P
L
K
T
A
K
D
Y
P
R
R
W
S
D
D
I
Y
T
D
V
M
T
C
V
E
I
A
K
Q
A
G
L
E
T
L
V
L
D
Q
--
T
R
-----------------
P
D
-
I
G
L
N
V
V
K
V
I
-----------------------------
V
P
G
--------------------
M
R
F
W
--
S
R
F
G
S
G
R
L
Y
D
V
P
-
V
K
L
G
W
R
E
Q
P
---
L
A
E
A
Q
M
N
P
T
P
MPF---
32
HHSearch
47.78
46%
-159
- C6 -
-
3HVZ
-
?
C:
[396-459]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
V
F
V
F
T
-
P
K
G
------------
D
V
I
S
L
P
I
G
S
T
V
I
D
F
A
Y
A
I
H
S
A
V
G
N
R
-
M
I
G
A
K
V
--
D
G
R
I
V
P
I
D
Y
K
V
-
K
T
G
E
I
I
D
V
L
T
T
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
46.79
49%
-169
- C6 -
-
3HVZ
-
?
A:
[396-459]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
V
F
V
F
T
-
P
K
G
------------
D
V
I
S
L
P
I
G
S
T
V
I
D
F
A
Y
A
I
H
S
A
V
G
N
R
-
M
I
G
A
K
V
--
D
G
R
I
V
P
I
D
Y
K
V
-
K
T
G
E
I
I
D
V
L
T
T
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.01
48%
-110
- C6 -
-
2KMM
-
?
A:
[418-483]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
M
V
F
T
-
P
K
G
------------
E
I
K
R
L
P
Q
G
A
T
A
L
D
F
A
Y
S
L
H
S
D
L
G
D
H
-
C
I
G
A
K
V
--
N
H
K
L
V
P
L
S
Y
V
L
-
N
S
G
D
Q
V
E
V
L
S
S
K
S
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
44.89
48%
-110
- C6 -
-
2KMM
-
?
A:
[418-481]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
M
V
F
T
-
P
K
G
------------
E
I
K
R
L
P
Q
G
A
T
A
L
D
F
A
Y
S
L
H
S
D
L
G
D
H
-
C
I
G
A
K
V
--
N
H
K
L
V
P
L
S
Y
V
L
-
N
S
G
D
Q
V
E
V
L
S
S
K
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
44.00
26%
64
- C5 -
-
3NR1
-
MESH1_HUMAN
B:
[3-178]
----------------------------------------------------------------------------------
E
A
A
Q
L
L
E
A
A
D
F
A
A
R
K
---------
H
R
Q
Q
R
R
K
DP
E
-
G
T
P
Y
I
N
H
P
I
G
-----
V
A
R
I
L
T
H
E
A
G
I-
T
D
I
V
V
L
Q
--
A
A
L
L
H
D
T
V
E
D
T
D
T
T
L
D
E
V
E
L
H
F
-----
G
A
Q
V
R
R
L
V
E
E
V
T
D
D
K
T
L
P
----
K
L
E
R
-----------------
K
R
---
L
Q
V
E
Q
---
A
P
H
S
S
P
G
A
K
L
----
V
K
L
A
D
K
L
Y
N
L
R
D
L
N
R
C
T
P
E
G---
W
S
E
H
--------------------------------------------
R
V
---
Q
E
Y
F
-----
E
W
A
A
Q
V
V
K
G
--
L
Q
G
T
N
R
Q
--
L
E
-
E
-
A
L
K
H
L
F
K
Q
R
G
L
T
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
42.50
28%
-24
- C5 -
-
3L9D
-
?
A:
[20-183]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
R
G
-----------
I
R
K
Q
F
R
K
Q
K
R
H
-----
S
P
I
-
E
F
V
T
G
R
V
-
K
P
I
E
S
I
K
E
K
M
V
L
R
G
I
K
KENL
T
Q
D
M
Q
-
D
I
A
G
L
R
I
M
V
Q
F
V
D
D
V
N
D
V
L
E
L
L
R
Q
R
K
D
M
K
--
V
I
Q
--
E
R
D
Y
I
N
N
---
K
P
S
G
Y
R
S
Y
H
------
V
I
V
E
Y
P
-------
V
D
T
IS
G
Q
R
I
I
M
A
E
I
Q
I
R
T
L
A
M
N
F
W
A
T
I
E
H
S
---
L
N
Y
K
Y
H
G
E
-
F
P
E
D
I
K
R
R
L
E
----
L
T
S
K
I
A
F
Q
L
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
42.17
50%
-48
- C6 -
-
3HVZ
-
?
A:
[396-459]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
V
F
V
F
T
-
P
K
G
------------
D
V
I
S
L
P
I
G
S
T
V
I
D
F
A
Y
A
I
H
S
A
V
G
N
R
M
I
-
G
A
K
V
--
D
G
R
I
V
P
I
D
Y
K
V
-
K
T
G
E
I
I
D
V
L
T
T
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
42.16
22%
-63
- C5 -
-
1Y7P
-
Y1403_ARCFU
B:
[2-81]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
L
R
G
L
R
I
I
A
E
N
K
-----------------
I
G
-
V
L
R
D
L
T
T
I
I
A
E
E
G
G
N
I
T
F
A
Q
T
F
L
I
K
H
G
EH---------
E
G
K
--------------------
A
L
I
Y
-
F
E
I
E
G
-
G
D
F
E
K
I
L
-
E
R
V
K
T
F
D
Y
I
---
I
E
I
E
E
E
E
S
--------
23
HHSearch
41.90
28%
-25
- C5 -
-
3L9D
-
?
B:
[20-183]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
R
G
-----------
I
R
K
Q
F
R
K
Q
K
R
H
-----
S
P
I
-
E
F
V
T
G
R
V
-
K
P
I
E
S
I
K
E
K
M
V
L
R
G
I
K
KENL
T
Q
D
M
Q
-
D
I
A
G
L
R
I
M
V
Q
F
V
D
D
V
N
D
V
L
E
L
L
R
Q
R
K
D
M
K
--
V
I
Q
--
E
R
D
Y
I
N
N
-----
S
G
Y
R
S
Y
H
------
V
I
V
E
Y
P
-------
V
D
T
IS
G
Q
R
I
I
M
A
E
I
Q
I
R
T
L
A
M
N
F
W
A
T
I
E
H
S
---
L
N
Y
K
Y
H
G
E
-
F
P
E
D
I
K
R
R
L
E
----
L
T
S
K
I
A
F
Q
L
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
40.98
27%
-46
- C5 -
-
5F2V
1
YJBM_BACSU
T:
[38-183]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
F
V
T
G
R
V
-
K
P
V
A
S
I
L
E
K
A
R
R
K
S
I
P
LHE-
I
E
T
M
Q
-
D
I
A
G
L
R
I
M
C
Q
F
V
D
D
I
Q
I
V
K
E
M
L
F
A
R
K
D
F
T
--
V
V
D
--
Q
R
D
Y
I
A
E
H
--
K
E
S
G
Y
R
S
Y
H
------
L
V
V
L
Y
P
LQTVSGE
K
-------
H
V
L
V
E
I
Q
I
R
T
L
A
M
N
F
W
A
T
I
E
H
S
---
L
N
Y
K
Y
S
G
N
-
I
P
E
K
V
K
L
R
L
Q
----
R
A
S
E
A
A
S
R
L
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
40.80
29%
96
- C5 -
-
3NR1
-
MESH1_HUMAN
A:
[1-135]
--------------------------------------------------------------------------------
G
S
E
A
A
Q
L
L
E
A
A
D
F
A
A
R
K
H
R
QQRRKDP
E
G
T
P
-
Y
I
--
N
H
-------
P
I
G
-----
V
A
R
I
L
T
-
H
E
A
GI
T
D
I
V
V
L
Q
--
A
A
L
L
H
D
T
V
E
D
T
D
T
T
L
D
E
V
E
L
H
F
-----
G
A
Q
V
R
R
L
V
E
E
V
T
D
D
K
T
L
P
----
K
L
E
R
K
R
L
Q
V
E
-----------
Q
A
P
H
S
S
P
G
A
K
------------
L
----
V
K
L
A
D
K
L
Y
N
L
R
D
L
N
R
C
T
P
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
40.38
13%
-49
- C5 -
-
4YF1
-
?
A:
[28-162]
--------------------------------------------------------------------------------------------------------------------
T
G
E
P
Y
F
S
H
P
L
N
-----
V
A
R
I
L
R
-
R
A
G
--
F
R
E
E
V
V
V
--
A
G
L
L
H
D
A
V
E
D
T
E
M
T
D
A
D
I
R
A
T
F
-----
G
D
E
V
A
D
L
V
A
S
H
T
E
N
K
T
L
S
----
W
E
--------------------
E
R
K
A
H
T
I
E
Q
V
R
T
---
G
N
L
E
E
K
A
----
L
I
V
A
D
K
L
D
N
L
T
S
V
K
Y
A
L
S
S
KS--
V
W
S
Y
--------------------------------------------
F
K
RG
Y
D
L
Q
K
-----
W
Y
N
Q
G
I
K
N
N
M
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
40.30
31%
-90
- C6 -
-
1WXQ
-
?
A:
[342-395]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
L
M
K
K
G
S
T
P
R
D
L
A
F
K
V
H
T
D
L
G
K
G
-
F
L
Y
A
I
N
AR
T
K
R
R
V
G
E
D
Y
E
L
-
Q
F
N
D
I
V
K
I
V
S
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
39.69
34%
4
- C5 -
-
2BE3
2
?
A:
[43-188]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
V
T
G
R
V
-
K
P
I
E
S
I
K
E
K
M
A
R
R
G
I
T
YATL
E
H
D
L
Q
-
D
I
A
G
L
R
V
M
V
Q
F
V
D
D
V
K
E
V
V
D
I
L
H
K
R
Q
D
M
R
--
I
I
Q
--
E
R
D
Y
I
T
H
R
--
K
A
S
G
Y
R
S
Y
H
------
V
V
V
E
Y
T
V
D
T
IN
G
A
K
-------
T
I
L
A
E
I
Q
I
R
T
L
A
M
N
F
W
A
T
I
E
H
S
---
L
N
Y
K
Y
Q
G
D
-
F
P
D
E
I
K
K
R
L
E
----
I
T
A
R
I
A
H
Q
L
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
39.09
13%
-87
- C5 -
-
4YF1
-
?
D:
[34-162]
--------------------------------------------------------------------------------------------------------------------------
S
H
P
L
N
-----
V
A
R
I
L
R
-
R
A
G
--
F
R
E
E
V
V
V
--
A
G
L
L
H
D
A
V
E
D
T
E
M
T
D
A
D
I
R
A
T
F
-----
G
D
E
V
A
D
L
V
A
S
H
T
E
N
K
T
L
S
----
W
E
--------------------
E
R
K
A
H
T
I
E
Q
V
R
T
---
G
N
L
E
E
K
A
----
L
I
V
A
D
K
L
D
N
L
T
S
V
K
Y
A
L
S
S
EGKS
V
W
S
Y
--------------------------------------------
F
K
RG
Y
D
L
Q
K
-----
W
Y
N
Q
G
I
K
N
N
M
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
38.96
27%
-23
- C5 -
-
3IBW
-
?
A:
[653-731]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
F
L
A
G
I
R
I
V
G
E
D
K
-----------------
N
G
M
T
-
N
Q
I
T
G
V
I
S
K
F
D
T
N
I
R
T
I
V
L
N
A
K
-
D
G
-----------
I
F
T
--------------------
C
N
L
-
M
I
F
V
K
N
T
D
K
L
T
T
L
-
M
D
K
L
R
K
V
Q
G
V
---
F
T
V
E
R
L
S
N
--------