@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKL7: (2017-10-27 )
MALLRIEKNNGIATVYLNRPDKRNAMSFALLKELVTTAKAIQKDRDIRCVILTGEAQVFSAGIDLSDLNNPKNSAFAIWELVKPGQSLFQKAFLIWQNLPVPVIAALEGYCFGAGMQLALAADIRIAHPDTKMSIMESRWGLVPDMGLTRSLKGLIGVDLAKELTLTARVLDGNYAKDIGLVTHLSENPLEKANAIASEMLQRSPDALTAAKRVLDAMEHQPEKSLRLEKIWQLKLLLGKNSKLARKKDKHPEVKFLPRQYR
Atome Classification :
(20 SA)
----.........10........20........30........40........50.....-...60....----..-----.---.70....-----...--..80-........90........100.......110.......120.......130.......140.-..-....150.....-..160.......170.......180--..--.---..--..---190-----........200.......210-.-.----..-.-..220.-......230....-..---.240-......---..250-.........260
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----M
A
L
L
R
I
EKNN
G
I
A
T
V
Y
LNRPDKR
N
A
M
S
F
A
L
L
K
E
L
V
T
T
A
K
A
I
QKDR
D
I
R
C
V
I
L
TGE
A
-
Q
V
F
SAGIDL----SD-----L---NN-PKNS-----
A
F
A
--
I
W
E
L-VKP
G
Q
S
L
F
Q
K
A
F
L
I
W
QNLP
V
P
V
I
A
A
LEGYCFGAG
M
Q
L
A
L
A
A
D
I
R
IAHPD
T
K
M
S
I
M
E
S
RWGLV-PD-M
G
L
T
R
S
L
K
G
L
I
G
-
V
D
L
A
K
E
L
T
L
T
A
R
VLDGNYAKDI
G
L
V
--TH--L---SE--NP---
L
E
------
K
A
N
A
I
A
S
E
M
L
QRSP
D
A
L
T
A
A
K
-
R
-
V
----
L
D
-
A
-
M
EHQ
P
E
-
K
S
L
R
L
E
K
I
W
Q
L
K
L
-
L
L---GKN--SKLARK---KDK---HPEVKFLPRQYR
1
PsiBlast_PDB
85.58
35%
-125
- C3 -
-
4OG1
1
?
A:
[40-277]
---------------
V
A
H
V
L
L
D
R
A
D
K
M
N
A
L
D
D
A
M
F
E
G
I
V
A
A
G
H
H
L
H
S
V
K
G
V
R
C
V
V
L
S
G
A
G
-
R
S
F
C
A
G
L
D
L
----
S
------------------------
S
--
L
T
E
R
-
T
H
G
N
A
N
R
A
Q
Q
A
A
M
V
W
R
K
L
P
M
P
V
I
A
A
V
H
G
V
C
F
G
G
G
L
Q
V
A
S
G
A
D
I
R
F
I
T
P
D
A
R
L
A
V
M
E
V
K
W
G
L
V
-
P
D
-
M
A
G
Y
A
L
W
R
G
N
V
R
-
D
D
V
L
R
E
L
T
Y
T
H
R
E
F
S
G
E
E
A
V
R
F
G
F
A
--
T
H
--
V
---
A
D
--
D
P
---
L
A
------
G
A
M
E
L
A
R
V
V
A
E
K
S
P
N
A
V
R
G
A
K
-
T
-
L
----
S
N
R
A
-
P
D
L
T
V
D
-
D
V
L
M
A
E
S
I
A
Q
H
E
L
-
M
Y
---
S
R
N
--
Q
M
E
A
V
K
---------------------
73
HHSearch
83.60
33%
-91
- C3 -
-
4JCS
-
?
A:
[3-263]
------
T
L
D
F
E
V
V
N
N
V
G
W
I
R
M
N
R
A
A
K
H
N
P
F
D
A
E
L
R
A
D
L
M
T
V
L
E
R
V
R
D
D
A
D
I
R
V
L
V
L
T
S
H
P
-
G
S
F
C
A
--
N
L
----
H
V
-----
L
---
R
D
-
N
L
D
S
-----
G
P
A
--
Y
W
Q
---
Q
R
I
K
T
G
L
R
F
-
I
H
D
M
L
N
L
G
R
P
V
I
A
A
V
D
G
P
A
F
G
A
G
F
A
L
S
L
T
A
D
I
V
L
A
S
P
R
A
R
F
S
M
A
Y
L
R
L
G
L
V
-
P
D
-
L
G
A
L
Y
L
L
P
R
A
V
G
-
L
Q
R
A
K
E
L
M
F
S
T
R
E
L
D
A
E
E
A
H
R
L
G
L
V
--
M
E
--
V
---
H
E
SE
A
L
---
E
Q
------
R
A
R
E
I
A
E
S
L
V
Q
A
A
P
T
A
L
A
L
T
K
-
A
-
A
----
L
N
-
V
-
S
L
D
S
D
E
Q
T
M
F
S
L
E
A
A
S
Q
A
A
A
-
F
S
---
T
K
E
--
P
R
A
A
I
E
---
A
L
L
S
KQ
P
P
P
F
R
G
F
P
R
R
--
4
PsiBlast_PDB
82.06
32%
-59
- C3 -
-
4JCS
-
?
A:
[4-263]
-------
L
D
F
E
V
V
N
N
V
G
W
I
R
M
N
R
A
A
K
H
N
P
F
D
A
E
L
R
A
D
L
M
T
V
L
E
R
V
R
D
D
A
D
I
R
V
L
V
L
T
S
H
P
-
G
S
F
C
A
--
N
L
----
H
V
-----
L
---
R
D
-
N
L
D
S
-----
G
P
A
--
Y
W
Q
Q
R
I
K
T
G
L
R
F
I
H
D
M
L
----
N
L
G
R
P
V
I
A
A
V
D
G
P
A
F
G
A
G
F
A
L
S
L
T
A
D
I
V
L
A
S
P
R
A
R
F
S
M
A
Y
L
R
L
G
L
V
-
P
D
-
L
G
A
L
Y
L
L
P
R
A
V
G
-
L
Q
R
A
K
E
L
M
F
S
T
R
E
L
D
A
E
E
A
H
R
L
G
L
V
M
E
V
H
--
E
---
S
E
--
A
L
---
E
Q
------
R
A
R
E
I
A
E
S
L
V
Q
A
A
P
T
A
L
A
L
T
K
-
A
-
A
----
L
N
V
S
-
L
D
S
D
E
Q
-
T
M
F
S
L
E
A
A
S
Q
A
A
A
-
F
S
---
T
K
E
--
P
R
A
A
I
E
A
L
L
S
K
Q
---
P
P
P
F
R
G
F
P
R
R
--
9
PsiBlast_PDB
79.17
32%
-98
- C3 -
-
3HRX
-
?
A:
[5-227]
----------
E
R
Q
D
G
V
L
V
L
T
L
N
R
P
E
K
L
N
A
I
T
G
E
L
L
D
A
L
Y
A
A
L
K
E
G
E
E
D
R
E
V
R
A
L
L
L
T
G
A
G
-
R
A
F
S
A
G
Q
D
L
----
T
E
-----
F
---
G
D
-
R
K
P
D
-----
Y
E
A
--
H
L
R
--------
R
Y
N
R
V
V
E
A
L
S
G
L
E
K
P
L
V
V
A
V
N
G
V
A
A
G
A
G
M
S
L
A
L
W
G
D
L
R
L
A
A
V
G
A
S
F
T
T
A
F
V
R
I
G
L
V
-
P
D
-
S
G
L
S
F
L
L
P
R
L
V
G
-
L
A
K
A
Q
E
L
L
L
L
S
P
R
L
S
A
E
E
A
L
A
L
G
L
V
--
H
R
--
V
VP-
A
E
--
K
L
---
M
E
------
E
A
L
S
L
A
K
E
L
A
Q
G
P
T
R
A
Y
A
L
T
K
-
K
L
L
----
L
E
-
T
-
Y
R
L
S
L
T
-
E
A
L
A
L
E
A
V
L
Q
-----------------------------------------
82
HHSearch
78.75
28%
-97
- C3 -
-
3HIN
-
?
A:
[17-266]
------
T
L
V
V
D
T
V
G
P
V
L
T
I
G
L
N
R
P
K
K
R
N
A
L
N
D
G
L
M
A
A
L
K
D
C
L
T
D
I
P
--
D
Q
I
R
A
V
V
I
H
G
I
G
-
D
H
F
S
A
G
L
D
L
----
S
E
-----
L
---
R
E
-
R
D
A
T
-----
E
G
L
--
V
H
------
S
Q
T
W
H
R
V
-
F
D
K
I
Q
Y
C
R
V
P
V
I
A
A
L
K
G
A
V
I
G
G
G
L
E
L
A
C
A
A
H
I
R
V
A
E
A
S
A
Y
Y
A
L
P
E
G
S
R
G
I
F
-
V
G
-
G
G
G
S
V
R
L
P
R
L
I
G
-
V
A
R
M
A
D
M
M
L
T
G
R
V
Y
S
A
A
E
G
V
V
H
G
F
S
--
Q
Y
--
L
---
I
E
NG
S
A
---
Y
D
------
K
A
L
E
L
G
N
R
V
A
Q
N
A
P
L
T
N
F
A
V
L
-
Q
-
A
----
L
P
-
M
-
I
A
E
A
N
P
Q
T
G
L
L
M
E
S
L
M
A
T
V
A
-
Q
S
---
D
Q
E
--
A
K
T
R
I
R
---
A
F
L
D
H
K
T
A
K
V
--------
81
HHSearch
77.72
28%
-99
- C3 -
-
3HIN
-
?
B:
[17-261]
------
T
L
V
V
D
T
V
G
P
V
L
T
I
G
L
N
R
P
K
K
R
N
A
L
N
D
G
L
M
A
A
L
K
D
C
L
T
D
I
P
--
D
Q
I
R
A
V
V
I
H
G
I
G
-
D
H
F
S
A
G
L
D
L
----
S
E
-----
L
---
R
E
-
R
D
A
T
-----
E
G
L
--
V
H
------
S
Q
T
W
H
R
V
-
F
D
K
I
Q
Y
C
R
V
P
V
I
A
A
L
K
G
A
V
I
G
G
G
L
E
L
A
C
A
A
H
I
R
V
A
E
A
S
A
Y
Y
A
L
P
E
G
S
R
G
I
F
-
V
G
-
G
G
G
S
V
R
L
P
R
L
I
G
-
V
A
R
M
A
D
M
M
L
T
G
R
V
Y
S
A
A
E
G
V
V
H
G
F
S
--
Q
Y
--
L
---
I
E
NG
S
A
---
Y
D
------
K
A
L
E
L
G
N
R
V
A
Q
N
A
P
L
T
N
F
A
V
L
-
Q
-
A
----
L
P
-
M
-
I
A
E
A
N
P
Q
T
G
L
L
M
E
S
L
M
A
T
V
A
-
Q
S
---
D
Q
E
--
A
K
T
R
I
R
---
A
F
L
D
H-------------
21
PsiBlast_CBE
77.69
35%
-33
- C3 -
-
1DCI
5
ECH1_RAT
C:
[17-249]
------------------
V
Q
L
N
R
P
E
K
R
N
A
M
N
R
A
F
W
R
E
L
V
E
C
F
Q
K
I
S
K
D
S
D
C
R
A
V
V
V
S
G
A
G
-
K
M
F
T
S
G
I
D
L
----
M
D
MASDI
L
---
Q
P
-
P
G
D
D
-----
V
A
R
--
I
A
W
Y
-
L
R
D
L
I
S
R
Y
Q
K
T
F
T
V
I
E
K
C
P
K
P
V
I
A
A
I
H
G
G
C
I
G
G
G
V
D
L
I
S
A
C
D
I
R
Y
C
T
Q
D
A
F
F
Q
V
K
E
V
D
V
G
L
A
-
A
D
-
V
G
T
L
Q
R
L
P
K
V
I
G
N
R
S
L
V
N
E
L
T
F
T
A
R
K
M
M
A
D
E
A
L
D
S
G
L
V
--
S
R
--
V
---
F
P
--
D
K
DVM
L
N
------
A
A
F
A
L
A
A
D
I
S
S
K
S
P
V
A
V
Q
G
S
K
I
N
-
L
----
I
Y
-
S
-
R
D
H
S
V
D
-
E
S
L
D
Y
M
A
T
W
N
M
S
M
-
L
------------------------------------
2
PsiBlast_PDB
77.69
35%
-36
- C3 -
-
1DCI
4
ECH1_RAT
A:
[17-249]
------------------
V
Q
L
N
R
P
E
K
R
N
A
M
N
R
A
F
W
R
E
L
V
E
C
F
Q
K
I
S
K
D
S
D
C
R
A
V
V
V
S
G
A
G
-
K
M
F
T
S
G
I
D
L
----
M
D
M
A
S
D
I
L
---
Q
P
-
P
G
D
D
-----
V
A
R
--
I
A
W
Y
-
L
R
D
L
I
S
R
Y
Q
K
T
F
T
V
I
E
K
C
P
K
P
V
I
A
A
I
H
G
G
C
I
G
G
G
V
D
L
I
S
A
C
D
I
R
Y
C
T
Q
D
A
F
F
Q
V
K
E
V
D
V
G
L
A
-
A
D
-
V
G
T
L
Q
R
L
P
K
V
I
G
N
R
S
L
V
N
E
L
T
F
T
A
R
K
M
M
A
D
E
A
L
D
S
G
L
V
--
S
R
--
V
---
F
P
--
D
K
D
V
M
L
N
------
A
A
F
A
L
A
A
D
I
S
S
K
S
P
V
A
V
Q
G
S
K
I
N
-
L
----
I
Y
-
S
-
R
D
H
S
V
D
-
E
S
L
D
Y
M
A
T
W
N
M
S
M
-
L
------------------------------------
35
PsiBlast_CBE
77.67
31%
-51
- C3 -
-
3SLL
2
?
E:
[34-283]
---------------
I
A
L
V
T
L
N
R
P
E
R
M
N
A
M
A
F
D
V
M
L
P
F
K
Q
M
L
V
D
I
S
H
D
N
D
V
R
A
V
V
I
T
G
A
G
-
K
G
F
C
S
G
A
D
-----------------
P
I
P
H
I
G
-----
G
L
T
--
Q
P
T
I
-
A
L
R
S
M
E
L
L
D
E
V
I
L
T
L
R
R
M
H
Q
P
V
I
A
A
I
N
G
A
A
I
G
G
G
L
C
L
A
L
A
C
D
V
R
V
A
S
Q
D
A
Y
F
R
A
A
G
I
N
N
G
L
T
A
S
E
-
L
G
L
S
Y
L
L
P
R
A
I
G
-
T
S
R
A
S
D
I
M
L
T
G
R
D
V
D
A
D
E
A
E
R
I
G
L
V
--
S
R
K
V
A
---
S
E
--
S
L
---
L
E
------
E
C
Y
A
I
G
E
R
I
A
G
F
S
R
P
G
I
E
L
T
K
-
R
-
T
I
W
S
G
L
D
-
A
-
A
S
L
--
E
-
S
H
M
H
Q
E
G
L
G
Q
L
Y
V
R
L
L
---
T
D
N
F
E
E
A
T
A
A
R
---
K
E
K
---
R
P
----------
3
PsiBlast_PDB
77.46
35%
-47
- C3 -
-
2VRE
-
ECH1_HUMAN
A:
[44-276]
------------------
V
Q
L
N
R
P
N
K
R
N
A
M
N
K
V
F
W
R
E
M
V
E
C
F
N
K
I
S
R
D
A
D
C
R
A
V
V
I
S
G
A
G
-
K
M
F
T
A
G
I
D
L
M
D
M
A
S
D
-----
I
---
L
Q
-
P
K
G
D
-----
D
V
A
R
I
S
W
Y
L
--
R
D
I
I
T
R
Y
Q
E
T
F
N
V
I
E
R
C
P
K
P
V
I
A
A
V
H
G
G
C
I
G
G
G
V
D
L
V
T
A
C
D
I
R
Y
C
A
Q
D
A
F
F
Q
V
K
E
V
D
V
G
L
A
-
A
D
-
V
G
T
L
Q
R
L
P
K
V
I
G
N
Q
S
L
V
N
E
L
A
F
T
A
R
K
M
M
A
D
E
A
L
G
S
G
L
V
--
S
R
--
V
FPD
K
E
--
V
M
---
L
D
------
A
A
L
A
L
A
A
E
I
S
S
K
S
P
V
A
V
Q
S
T
K
V
N
-
L
----
L
Y
-
S
-
R
D
H
S
V
A
-
E
S
L
N
Y
V
A
S
W
N
M
S
M
-
L
------------------------------------
90
HHSearch
76.64
30%
-86
- C3 -
-
3G64
1
?
C:
[19-277]
-------
L
R
V
E
I
T
D
G
V
A
T
V
T
L
A
R
P
D
K
L
N
A
L
T
F
E
A
Y
A
D
L
R
D
L
L
A
E
L
S
R
R
R
A
V
R
A
L
V
L
A
G
E
G
-
R
G
F
C
S
G
G
D
V
----
D
E
-----
I
---
I
G
-
A
T
L
S
-----
M
D
T
--
A
R
L
--
L
D
F
N
R
M
T
G
Q
V
-
V
R
A
V
R
E
C
P
F
P
V
I
A
A
L
H
G
V
A
A
G
A
G
A
V
L
A
L
A
A
D
F
R
V
A
D
P
S
T
R
F
A
F
L
F
T
R
V
G
L
S
-
G
G
D
M
G
A
A
Y
L
L
P
R
V
V
G
-
L
G
H
A
T
R
L
L
M
L
G
D
T
V
R
A
P
E
A
E
R
I
G
L
I
--
S
E
--
L
---
T
E
EG
R
A
---
D
E
------
A
A
R
T
L
A
R
R
L
A
D
G
P
A
L
A
H
A
Q
T
K
-
A
-
L
----
L
T
-
A
-
E
L
D
M
P
L
A
A
A
V
E
L
D
A
S
T
Q
A
L
L
-
M
T
---
G
E
D
--
Y
A
E
F
H
A
---
A
F
T
EKR
P
P
K
W
Q
G
R
-----
36
PsiBlast_CBE
76.47
31%
-48
- C3 -
-
3SLL
2
?
D:
[34-283]
---------------
I
A
L
V
T
L
N
R
P
E
R
M
N
A
M
A
F
D
V
M
L
P
F
K
Q
M
L
V
D
I
S
H
D
N
D
V
R
A
V
V
I
T
G
A
G
-
K
G
F
C
S
-------------------
G
P
I
P
H
I
G
-----
G
L
T
--
Q
P
T
I
-
A
L
R
S
M
E
L
L
D
E
V
I
L
T
L
R
R
M
H
Q
P
V
I
A
A
I
N
G
A
A
I
G
G
G
L
C
L
A
L
A
C
D
V
R
V
A
S
Q
D
A
Y
F
R
A
A
G
I
N
N
G
L
T
A
S
E
-
L
G
L
S
Y
L
L
P
R
A
I
G
-
T
S
R
A
S
D
I
M
L
T
G
R
D
V
D
A
D
E
A
E
R
I
G
L
V
--
S
R
K
V
A
---
S
E
--
S
L
---
L
E
------
E
C
Y
A
I
G
E
R
I
A
G
F
S
R
P
G
I
E
L
T
K
-
R
-
T
I
W
S
G
L
D
-
A
-
A
S
L
--
E
-
S
H
M
H
Q
E
G
L
G
Q
L
Y
V
R
L
L
---
T
D
N
F
E
E
A
T
A
A
R
---
K
E
K
---
R
P
----------
38
PsiBlast_CBE
75.53
31%
-53
- C3 -
-
3SLL
2
?
B:
[34-283]
---------------
I
A
L
V
T
L
N
R
P
E
R
M
N
A
M
A
F
D
V
M
L
P
F
K
Q
M
L
V
D
I
S
H
D
N
D
V
R
A
V
V
I
T
G
A
G
-
K
G
F
C
S
---------------
A
---
G
P
I
P
H
I
G
-----
G
L
T
--
Q
P
T
I
-
A
L
R
S
M
E
L
L
D
E
V
I
L
T
L
R
R
M
H
Q
P
V
I
A
A
I
N
G
A
A
I
G
G
G
L
C
L
A
L
A
C
D
V
R
V
A
S
Q
D
A
Y
F
R
A
A
G
I
N
N
G
L
T
A
S
E
-
L
G
L
S
Y
L
L
P
R
A
I
G
-
T
S
R
A
S
D
I
M
L
T
G
R
D
V
D
A
D
E
A
E
R
I
G
L
V
--
S
R
K
V
A
---
S
E
--
S
L
---
L
E
------
E
C
Y
A
I
G
E
R
I
A
G
F
S
R
P
G
I
E
L
T
K
-
R
-
T
I
W
S
G
L
D
-
A
-
A
S
L
--
E
-
S
H
M
H
Q
E
G
L
G
Q
L
Y
V
R
L
L
---
T
D
N
F
E
E
A
T
A
A
R
---
K
E
K
---
R
P
----------
6
PsiBlast_PDB
75.27
37%
-43
- C3 -
-
2ZQQ
-
AUHM_HUMAN
A:
[84-290]
----------
E
E
N
R
G
I
V
V
L
G
I
N
R
A
Y
G
K
N
S
L
S
K
N
L
I
K
M
L
S
K
A
V
D
A
L
K
S
D
K
K
V
R
T
I
I
I
R
S
E
V
P
G
I
F
C
A
G
A
D
L
----
K
E
-----
R
---
A
K
-
M
S
S
S
-----
E
---------
V
G
P
F
V
S
K
I
R
A
V
I
N
D
I
A
N
L
P
V
P
T
I
A
A
I
D
G
L
A
L
G
G
G
L
E
L
A
L
A
C
D
I
R
V
A
A
S
S
A
K
M
G
L
V
E
T
K
L
A
I
I
-
P
G
-
G
G
G
T
Q
R
L
P
R
A
I
G
-
M
S
L
A
K
E
L
I
F
S
A
R
V
L
D
G
K
E
A
K
A
V
G
L
I
--
S
H
--
V
---
L
E
--
Q
N
---
Q
E
GD
A
A
Y
R
K
A
L
D
L
A
R
E
F
L
P
Q
G
P
V
A
M
R
V
A
K
-----------------------------------------------------------------------
27
PsiBlast_CBE
75.12
32%
-70
- C3 -
-
4DI1
1
?
C:
[25-233]
------
F
V
S
V
V
A
D
Q
G
L
A
T
L
V
V
S
R
P
-
P
T
N
A
M
T
R
Q
V
Y
R
E
I
V
A
A
A
D
E
L
G
R
R
D
D
I
G
A
V
V
L
F
G
G
H
-
E
I
F
S
A
G
D
D
M
----
P
E
-----
L
RTL
N
A
-
P
E
A
D
-----
T
A
A
--
R
V
R
L
----------
E
A
I
D
A
V
A
A
I
P
K
P
T
V
A
A
V
T
G
Y
A
L
G
A
G
L
T
L
A
L
A
A
D
W
R
V
S
G
D
N
V
K
F
G
A
T
E
I
L
A
G
L
I
-
P
G
-
G
G
G
M
G
R
L
T
R
V
V
G
-
S
S
R
A
K
E
L
V
F
S
G
R
F
F
D
A
E
E
A
L
A
L
G
L
I
--
D
D
--
M
VA-
P
D
--
D
V
---
Y
D
------
S
A
V
A
W
A
R
R
Y
L
E
C
P
P
R
A
L
A
A
A
K
-
A
-
V
----
I
N
-------------------------------------------------------------
5
PsiBlast_PDB
75.10
37%
-45
- C3 -
-
1HZD
-
AUHM_HUMAN
A:
[84-290]
----------
E
E
N
R
G
I
V
V
L
G
I
N
R
A
Y
G
K
N
S
L
S
K
N
L
I
K
M
L
S
K
A
V
D
A
L
K
S
D
K
K
V
R
T
I
I
I
R
S
E
V
P
G
I
F
C
A
G
A
D
L
----
K
E
-----
R
---
A
K
-
M
S
S
S
-----
E
---------
V
G
P
F
V
S
K
I
R
A
V
I
N
D
I
A
N
L
P
V
P
T
I
A
A
I
D
G
L
A
L
G
G
G
L
E
L
A
L
A
C
D
I
R
V
A
A
S
S
A
K
M
G
L
V
E
T
K
L
A
I
I
-
P
G
-
G
G
G
T
Q
R
L
P
R
A
I
G
-
M
S
L
A
K
E
L
I
F
S
A
R
V
L
D
G
K
E
A
K
A
V
G
L
I
--
S
H
--
V
---
L
E
--
Q
N
---
Q
E
GD
A
A
Y
R
K
A
L
D
L
A
R
E
F
L
P
Q
G
P
V
A
M
R
V
A
K
-----------------------------------------------------------------------
96
Fugue
74.89
33%
5
- C3 -
-
1DCI
4
ECH1_RAT
A:
[1-275]
AYES
I
Q
V
T
S
A
Q
K
--
H
V
L
H
V
Q
L
N
R
P
E
K
R
N
A
M
N
R
A
F
W
R
E
L
V
E
C
F
Q
K
I
S
K
D
S
D
C
R
A
V
V
V
S
G
A
G
-
K
M
F
T
S
G
I
D
L
----
M
D
-----
M
---
A
S
-
D
I
L
Q
P
P
G
DD
V
A
R
--
I
A
W
Y
-
L
R
D
L
I
S
R
Y
Q
K
T
F
T
V
I
E
K
C
P
K
P
V
I
A
A
I
H
G
G
C
I
G
G
G
V
D
L
I
S
A
C
D
I
R
Y
C
T
Q
D
A
F
F
Q
V
K
E
V
D
V
G
L
A
-
A
D
-
V
G
T
L
Q
R
L
P
K
V
I
G
N
R
S
L
V
N
E
L
T
F
T
A
R
K
M
M
A
D
E
A
L
D
S
G
L
V
--
S
R
--
V
FPD
K
D
--
V
M
---
L
N
------
A
A
F
A
L
A
A
D
I
S
S
K
S
P
V
A
V
Q
G
S
K
-
I
-
N
----
L
I
-
Y
S
R
D
H
S
V
D
-
E
S
L
D
Y
M
A
T
W
N
M
S
M
-
L
Q
TQ
D
I
I
K
--
S
V
Q
A
A
M
---
E
K
K
---
D
S
K
S
I
T
F
S
K
L
--
22
PsiBlast_CBE
74.63
35%
-31
- C3 -
-
1DCI
4
ECH1_RAT
B:
[17-249]
------------------
V
Q
L
N
R
P
E
K
R
N
A
M
N
R
A
F
W
R
E
L
V
E
C
F
Q
K
I
S
K
D
S
D
C
R
A
V
V
V
S
G
A
G
-
K
M
F
T
S
G
I
D
L
----
M
D
MASDI
L
---
Q
P
-
P
G
D
D
-----
V
A
R
--
I
A
W
Y
-
L
R
D
L
I
S
R
Y
Q
K
T
F
T
V
I
E
K
C
P
K
P
V
I
A
A
I
H
G
G
C
I
G
G
G
V
D
L
I
S
A
C
D
I
R
Y
C
T
Q
D
A
F
F
Q
V
K
E
V
D
V
G
L
A
-
A
D
-
V
G
T
L
Q
R
L
P
K
V
I
G
N
R
S
L
V
N
E
L
T
F
T
A
R
K
M
M
A
D
E
A
L
D
S
G
L
V
--
S
R
--
V
---
F
P
--
D
K
DVM
L
N
------
A
A
F
A
L
A
A
D
I
S
S
K
S
P
V
A
V
Q
G
S
K
I
N
-
L
----
I
Y
-
S
-
R
D
H
S
V
D
-
E
S
L
D
Y
M
A
T
W
N
M
S
M
-
L
------------------------------------
37
PsiBlast_CBE
74.62
31%
-79
- C3 -
-
3SLL
2
?
C:
[34-283]
---------------
I
A
L
V
T
L
N
R
P
E
R
M
N
A
M
A
F
D
V
M
L
P
F
K
Q
M
L
V
D
I
S
H
D
N
D
V
R
A
V
V
I
T
G
A
G
-
K
G
F
C
S
----------------------
P
H
I
G
-----
G
L
T
--
Q
P
T
I
-
A
L
R
S
M
E
L
L
D
E
V
I
L
T
L
R
R
M
H
Q
P
V
I
A
A
I
N
G
A
A
I
G
G
G
L
C
L
A
L
A
C
D
V
R
V
A
S
Q
D
A
Y
F
R
A
A
G
I
N
N
G
L
T
A
S
E
-
L
G
L
S
Y
L
L
P
R
A
I
G
-
T
S
R
A
S
D
I
M
L
T
G
R
D
V
D
A
D
E
A
E
R
I
G
L
V
--
S
R
K
V
A
---
S
E
--
S
L
---
L
E
------
E
C
Y
A
I
G
E
R
I
A
G
F
S
R
P
G
I
E
L
T
K
-
R
-
T
I
W
S
G
L
D
-
A
-
A
S
L
--
E
-
S
H
M
H
Q
E
G
L
G
Q
L
Y
V
R
L
L
---
T
D
N
F
E
E
A
T
A
A
R
---
K
E
K
---
R
P
----------
64
PsiBlast_CBE
74.50
31%
-129
- C3 -
-
3PE8
1
?
A:
[10-203]
------
V
L
L
V
D
T
T
D
R
V
R
T
L
T
L
N
R
P
Q
S
R
N
A
L
S
A
E
L
R
S
T
F
F
R
A
L
S
D
A
Q
N
D
D
D
V
D
V
V
I
V
T
G
A
D
-
P
V
F
C
A
G
L
D
L
----
K
E
-----
L
--------------------------
S
P
K
----------
W
P
D
M
T
K
P
V
I
G
A
I
N
G
A
A
V
T
G
G
L
E
L
A
L
Y
C
D
I
L
I
A
S
E
N
A
K
F
A
D
T
H
A
R
V
G
L
M
-
P
T
-
W
G
L
S
V
R
L
P
Q
K
V
G
-
V
G
L
A
R
R
M
S
L
T
G
D
Y
L
S
A
Q
D
A
L
R
A
G
L
V
--
T
E
--
V
------------------------
V
A
H
D
------
D
L
L
T
A
A
R
-
R
-
V
----
A
A
-
S
-
I
V
G
N
N
Q
-
K
A
V
R
-----------------------------------------------