@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKQ8: (2017-10-28 )
MALIRKRRLTEQQQRRIEKQHKTRQEEVDTSQDLDGLVVQHYGRQLEVQALSVPAHHPEKPQVAEGEPEPFWKPIELNSVWRCHTRTNLELLVTGDRVKWQADPNTGLGIITAIHPRTSLLTRPDRYHKVKPVAANISLIVIVFAPLPEPAPTLIDRYLVACADANIPALLVLNKSDLLTENNPILDMLKEYENLGYEVMICHSKGDISALSQRLDGETVAFVGQSGVGKSSLINVLIPDAEQKTNIISENSALGQHTTTSTRLINFGRNGALIDSPGIREFGLWHLDLDKIRMGFPEIEAHLGSCQFRNCTHTHEKNCGLKQAVEAGEILPRRLDSFLRLIDEIQEAQQKN
Atome Classification :
(20 SA)
.........10........20----........-30...-----.....40........50........60........70........80.......---.---90........100----.....-----...110.......120.......130......-.140...-..-..150-.......160.......170.......-180---.-.---..--..--.190---.-....---...200-.--..-..--.--..210...----....220.......230.......-240-.-......250.......260.......270.......280-..-.....290.......300.......310.......320.......330.......340----.......350
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MA
L
I
R
K
R
RL
T
E
Q
Q
Q
R
R
I
E
K
Q
H
----
K
T
R
Q
EEVD-TSQ
D
L
-----
D
G
L
V
V
Q
HYGR
Q
L
E
V
Q
A
L
SVPAHHPEKPQVAEGEPEPFWKPIELN
S
V
W
R
CHTRT
N
---
L
---
E
L
L
V
TG
D
R
V
K
W
Q-----ADPNT-----G
L
G
I
I
T
A
IHPRTSLLTRPDRYHKVKPVAAN
I
S
-
L
I
V
I
V
FA-PL-PE
P
A
P
-
T
L
I
D
R
Y
L
V
A
CADANI
P
A
L
L
V
LNKSDLL-TEN---N-
P
---
I
L
--
D
M
--
L
K
E
----
Y
-
E
NLG---
Y
E
V
M
I
--
C
--HS-KG--
D
--
I
S
A
L
S
Q
RL----DG
E
T
V
A
F
VGQSGVGKS
S
L
I
N
V
LIP-DA
E
-
Q
-
K
TNIISENSALGQHTTT
S
T
R
L
I
NFGRNGALIDSPGIREF-G
L
-
W
H
L
D
L
D
K
I
RMG
F
P
E
I
E
A
H
LGS
C
Q
FRNCTHTHEKNCG
L
K
Q
A
V
E
A
G
E
I
L
P
R
R
L
D
S
F
L
R
L
I
----
D
E
I
Q
E
A
QQKN
54
HHSearch
74.02
44%
-2
- C3 -
-
5NO2
-
?
Z:
[4-309]
-----------------------------------
G
E
P
D
-----
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
A
D
-------------------------
G
D
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
-----
P
G
K
P
A
AEGVN
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
D
F
Y
D
G
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
A
C
E
T
L
Q
I
E
P
I
I
V
L
N
K
I
D
L
L
-
D
D
E
G--
M
A
F
---
V
N
--
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
--
S
S
H
T
Q
--
D
G-
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
-
L
Q
K
-
E
I
L
T
N
D
I
S
D
N
S
G
L
G
Q
H
T
T
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
L
C
K
Y
R
D
C
K
H
D
T
D
P
G
C
A
I
R
E
A
V
E
E
G
K
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
Q
V
K
T
R
-
7
PsiBlast_PDB
74.02
38%
-66
- C3 -
-
4A2I
-
RSGA_ECOLI
V:
[49-344]
--------------------------------------------
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
-------------
A
D
G
E
------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
-------
P
G
K
-----
V
K
G
I
V
E
A
V
H
-
E
T
S
V
L
T
R
P
-----
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
G
C
E
T
L
Q
V
E
P
L
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
------
M
--
D
F
--
V
N
E
QMDI
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
SS
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
------------
L
Q
N
E
I
L
---
T
N
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
H
C
K
Y
R
D
C
K
H
D
A
D
P
G
C
A
I
R
E
A
V
E
N
G
A
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
-------
52
HHSearch
73.26
41%
-52
- C3 -
-
4A2I
-
RSGA_ECOLI
V:
[45-344]
-----------------------------------
G
E
P
A
-----
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
A
D
-------------------------
G
E
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
-----
P
G
K
-------
V
K
G
I
V
E
A
V
H
E
T
S
V
L
T
-
R
P
V
-----
K
P
I
A
A
N
I
D
-
Q
I
V
-
I
V
S
A
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
G
C
E
T
L
Q
V
E
P
L
I
V
L
N
K
I
D
L
L
-
D
D
E
GM-
D
-
F
---
V
N
--
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
--
S
S
H
T
Q
--
D
G-
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
-
L
Q
N
------
E
--------
I
L
T
N
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
H
C
K
Y
R
D
C
K
H
D
A
D
P
G
C
A
I
R
E
A
V
E
N
G
A
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
-------
3
PsiBlast_PDB
71.94
40%
19
- C3 -
-
5UZ4
1
RSGA_ECOLI
Z:
[1-334]
--------
L
S
K
G
Q
Q
R
R
V
N
A
N
H
QRRL
K
T
S
K
E
K
P
D
-
Y
D
D
N
L
FGEPD
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
-------------
A
D
G
D
------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
PGKPA
A
E
G
V
N
-----
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
D
F
Y
D
G
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
A
C
E
T
L
Q
I
E
P
I
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
-
M
---
A
F
VN
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
SS
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
Q
K
E
-
I
-
L
T
N
D
I
S
D
-----------
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
L
C
K
Y
R
D
C
K
H
D
T
D
P
G
C
A
I
R
E
A
V
E
E
G
K
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
Q
V
----
51
HHSearch
70.93
42%
-6
- C3 -
-
2RCN
1
RSGA_SALTY
A:
[43-345]
---------------------------------L
F
G
E
P
A
-----
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
A
D
-------------------------
G
E
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
-----
P
G
K
-------
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
-----
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
G
C
E
T
L
Q
V
E
P
L
I
V
L
N
K
I
D
L
L
-
D
D
E
G
--
M
D
F
---
V
N
--
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
--
S
S
H
T
Q
--
D
G-
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
-
L
Q
N
E
I
-
L
T
N
-------------
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
H
C
K
Y
R
D
C
K
H
D
A
D
P
G
C
A
I
R
E
A
V
E
N
G
A
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
------
2
PsiBlast_PDB
68.65
39%
3
- C3 -
-
2RCN
1
RSGA_SALTY
A:
[43-345]
--------------------------------------
L
F
G
E
P
A
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
-------------
A
D
G
E
------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
P
G
K------------
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
-----
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
G
C
E
T
L
Q
V
E
P
L
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
------
M
--
D
F
--
V
N
E
Q
M
D
I
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
S
S
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
Q
N
E
-
I
-
L
T
N
-------------
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
H
C
K
Y
R
D
C
K
H
D
A
D
P
G
C
A
I
R
E
A
V
E
N
G
A
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
------
5
PsiBlast_PDB
68.25
45%
8
- C3 -
-
5NO3
-
?
Z:
[28-309]
-----------------------------------------------------------------------------------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
PGKPA
A
E
G
V
N
-----
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
D
F
Y
D
G
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
A
C
E
T
L
Q
I
E
P
I
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
-
M
---
A
F
VN
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
SS
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
Q
K
E
-
I
-
L
T
N
D
I
S
D
N
S
G
L
G
Q
H
T
T
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
L
C
K
Y
R
D
C
K
H
D
T
D
P
G
C
A
I
R
E
A
V
E
E
G
K
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
Q
V
K
T
R
-
6
PsiBlast_PDB
67.68
45%
9
- C3 -
-
5NO4
-
?
Z:
[28-309]
-----------------------------------------------------------------------------------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
PGKPA
A
E
G
V
N
-----
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
D
F
Y
D
G
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
A
C
E
T
L
Q
I
E
P
I
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
-
M
---
A
F
VN
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
SS
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
Q
K
E
-
I
-
L
T
N
D
I
S
D
N
S
G
L
G
Q
H
T
T
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
L
C
K
Y
R
D
C
K
H
D
T
D
P
G
C
A
I
R
E
A
V
E
E
G
K
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
Q
V
K
T
R
-
4
PsiBlast_PDB
67.56
45%
10
- C3 -
-
5NO2
-
?
Z:
[28-309]
-----------------------------------------------------------------------------------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
PGKPA
A
E
G
V
N
-----
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
D
F
Y
D
G
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
A
C
E
T
L
Q
I
E
P
I
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
-
M
---
A
F
VN
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
SS
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
Q
K
E
-
I
-
L
T
N
D
I
S
D
N
S
G
L
G
Q
H
T
T
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
L
C
K
Y
R
D
C
K
H
D
T
D
P
G
C
A
I
R
E
A
V
E
E
G
K
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
Q
V
K
T
R
-
1
PsiBlast_PDB
64.88
39%
4
- C3 -
-
2YKR
-
RSGA_ECOLI
W:
[35-337]
--------------------------------------
L
FGEPD
E
G
I
V
I
S
R
F
G
M
H
A
D
V
E
S
-------------
A
D
G
D
------------
V
H
R
C
N
I
R
R
T
---
I
---
R
S
L
V
T
G
D
R
V
V
W
R
PGK------------
V
K
G
I
V
E
A
V
H
E
R
T
S
V
L
T
R
P
-----
V
K
P
I
A
A
N
I
D
-
Q
I
V
I
V
S
A
-
I
L
-
P
E
L
S
L
-
N
I
I
D
R
Y
L
V
A
C
E
T
L
Q
I
E
P
I
I
V
L
N
K
I
D
L
L
-
D
D
E
---
G
-
M
---
A
F
VN
E
Q
--
M
D
I
----
Y
-
R
N
I
G
---
Y
R
V
L
M
--
V
SS
H
T
-
Q
D
--
G
--
L
K
P
L
E
E
A
L
----
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
Q
K
E
-
I
-
L
T
N
-------------
T
A
A
R
L
Y
H
F
P
H
G
G
D
V
I
D
S
P
G
V
R
E
F
-
G
L
-
W
H
L
E
P
E
Q
I
T
Q
G
F
V
E
F
H
D
Y
L
G
L
C
K
Y
R
D
C
K
H
D
T
D
P
G
C
A
I
R
E
A
V
E
E
G
K
I
A
E
T
R
F
E
N
Y
H
R
I
L
----
E
S
M
A
------
56
HHSearch
63.35
32%
3
- C3 -
-
1T9H
-
RSGA_BACSU
A:
[9-305]
------------------------------------
H
M
P
-----
E
G
K
I
I
K
A
L
S
G
F
Y
Y
V
L
D
E
S
E
-----------
D
S
-----------
D
K
V
I
Q
C
R
G
R
G
I
F--
R
KNK
I
T
P
L
V
G
D
Y
V
V
Y
Q
-----
A
E
N
-
D
-----
K
E
G
Y
L
M
E
I
K
E
R
T
N
E
L
I
R
P
P
--------
I
C
N
V
D
-
Q
A
V
L
V
F
S
A
V
Q
-
P
S
F
S
T
-
A
L
L
D
R
F
L
V
L
V
E
A
N
D
I
Q
P
I
I
C
I
T
K
M
D
L
I
-
E
D
Q
D
T
E
D
-
T
---
I
Q
--
A
Y
--
A
E
D
----
Y
-
R
N
I
G
---
Y
D
V
Y
L
--
T
--
S
S
K
D
Q
--
D
S-
L
A
D
I
I
P
H
F
----
Q
D
K
T
T
V
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
I
S
P
----------------------
T
R
H
V
E
L
I
H
T
S
-
G
G
L
V
A
D
T
P
G
F
S
S
L
-
E
F
-
T
D
I
E
E
E
E
L
G
Y
T
F
P
D
I
R
E
K
S
S
S
C
K
F
R
G
C
L
H
L
K
E
P
K
C
A
V
K
Q
A
V
E
D
G
E
L
K
Q
Y
R
Y
D
H
Y
V
E
F
M
----
T
E
I
K
D
R
K
P
--
55
HHSearch
60.15
31%
9
- C3 -
-
2YV5
1
RSGA_AQUAE
A:
[1-297]
-------------------------------
M
G
-
K
K
E
L
K
-----
R
G
L
V
V
D
R
E
A
Q
M
I
G
V
Y
L
F
E
D
------------------------
G
K
T
Y
R
G
I
P
R
G
K
VLK
K
---
T
K
I
Y
A
G
D
Y
V
W
G
E
-----
V
V
D
-
P
-----
N
T
F
A
I
E
E
V
E
E
R
K
N
L
L
I
R
P
K
--------
V
A
N
V
D
-
R
V
I
I
V
E
T
L
K
M
-
P
E
F
N
N
-
Y
L
L
D
N
M
L
V
V
Y
E
Y
F
K
V
E
P
V
I
V
F
N
K
I
D
L
L
-
N
E
E
E
K
-
K
-
E
---
L
E
--
R
W
--
I
S
I
----
Y
-
R
D
A
G
---
Y
D
V
L
K
--
V
--
S
A
K
T
G
--
E
G-
I
D
E
L
V
D
Y
L
----
E
G
F
I
C
I
L
A
G
P
S
G
V
G
K
S
S
I
L
S
R
L
T
G
-
E
E
--
L
-
R
T
Q
E
V
---------
T
T
T
G
V
R
L
I
P
F
G
K
G
S
F
V
G
D
T
P
G
F
S
K
V
-
E
A
T
M
F
V
K
P
R
E
V
R
N
Y
F
R
E
F
L
R
--
Y
Q
C
K
Y
P
D
C
T
H
T
N
E
P
G
C
A
V
K
E
A
V
K
N
G
E
I
S
C
E
R
Y
K
S
Y
L
K
I
I
----
K
V
Y
L
E
E
I
K
E
-
53
HHSearch
60.07
30%
18
- C3 -
-
1U0L
1
RSGA_THEMA
B:
[9-299]
------------------------------------
L
R
R
-----
R
G
I
V
V
S
F
H
S
N
M
V
T
V
E
D
E
E
T
------------------------
G
E
R
I
L
C
K
L
R
G
K
F--
R
LQN
L
K
I
Y
V
G
D
R
V
E
Y
T
-----
P
D
E
-
T
-----
G
S
G
V
I
E
N
V
L
H
R
K
N
L
L
T
K
P
H
--------
V
A
N
V
D
-
Q
V
I
L
V
V
T
V
K
M
-
P
E
T
S
T
-
Y
I
I
D
K
F
L
V
L
A
E
K
N
E
L
E
T
V
M
V
I
N
K
M
D
L
Y
-
D
E
D
DL-
R
-
K
---
V
R
--
E
L
--
E
E
I
----
Y
-
S
-
G
L
---
Y
P
I
V
K
--
T
--
S
A
K
T
G
--
M
G-
I
E
E
L
K
E
Y
L
----
K
G
K
I
S
T
M
A
G
L
S
G
V
G
K
S
S
L
L
N
A
I
N
P
-
G
L
K
-
L
-
R
-------------
T
T
T
T
A
Q
L
L
K
F
D
F
G
G
Y
V
V
D
T
P
G
F
A
N
L
-
E
I
-
N
D
I
E
P
E
E
L
K
H
Y
F
K
E
F
G
D
--
K
Q
C
F
F
S
D
C
N
H
V
D
E
P
E
C
G
V
K
E
A
V
E
N
G
E
I
A
E
S
R
Y
E
N
Y
V
K
M
F
----
Y
E
L
L
G
R
R
---
77
Fugue
59.63
28%
-25
- C3 -
-
1U0L
1
RSGA_THEMA
A:
[9-299]
------------------------------------
L
R
R
-----
R
G
I
V
V
S
F
H
S
N
M
V
T
V
E
D
E
E
--------------------
T
G
E
R
I
L
C
K
L
R
G
K
F
R
L
Q
---
N
---
L
K
I
Y
V
G
D
R
V
E
Y
T
-----
P
D
E
T
G
-----
S
-
G
V
I
E
N
V
L
H
R
K
N
L
L
T
K
P
H
--------
V
A
N
V
D
-
Q
V
I
L
V
V
T
V
K
M
-
P
E
T
S
T
-
Y
I
I
D
K
F
L
V
L
A
E
K
N
E
L
E
T
V
M
V
I
N
K
M
D
L
Y
D
E
D
D
---
L
-
R
---
K
V
--
R
E
--
L
E
E
----
I
-
Y
S
G
L
---
Y
P
I
V
K
T
S
A
--
K
T
-
G
M
--
G
--
I
E
E
L
K
E
Y
L
----
K
G
K
I
S
T
M
A
G
L
S
G
V
G
K
S
S
L
L
N
A
I
N
P
-
G
L
---------------
K
L
R
T
T
T
T
A
Q
L
L
K
F
D
F
G
G
Y
V
V
D
T
P
G
F
A
N
L
-
E
I
-
N
D
I
E
P
E
E
L
K
H
Y
F
K
E
F
G
D
K
--
Q
C
F
F
S
D
C
N
H
V
D
E
P
E
C
G
V
K
E
A
V
E
N
G
E
I
A
E
S
R
Y
E
N
Y
V
K
M
F
----
Y
E
L
L
G
R
R
---
8
PsiBlast_PDB
58.29
33%
-13
- C3 -
-
1T9H
-
RSGA_BACSU
A:
[52-302]
------------------------------------------------------------------------------------------------------------
L
V
G
D
Y
V
V
Y
Q
-----
A
E
-
N
D
-----
K
E
G
Y
L
M
E
I
K
E
R
T
N
E
L
I
R
P
-------
P
I
C
-
N
V
D
-
Q
A
V
L
V
F
S
-
A
V
Q
P
S
F
S
T
-
A
L
L
D
R
F
L
V
L
V
E
A
N
D
I
Q
P
I
I
C
I
T
K
M
D
L
I
-
E
D
Q
---
D
-
T
E
D
T
I
Q
--
A
Y
--
A
E
D
----
Y
-
R
N
I
G
---
Y
D
V
Y
L
--
T
--
S
S
-
K
D
QD
S
--
L
A
D
I
I
P
H
F
----
Q
D
K
T
T
V
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
I
S
P
----------------------
T
R
H
V
E
L
I
H
-
T
S
G
G
L
V
A
D
T
P
G
F
S
S
L
-
E
F
-
T
D
I
E
E
E
E
L
G
Y
T
F
P
D
I
R
E
K
S
S
S
C
K
F
R
G
C
L
H
L
K
E
P
K
C
A
V
K
Q
A
V
E
D
G
E
L
K
Q
Y
R
Y
D
H
Y
V
E
F
M
----
T
E
I
K
D
-----
9
PsiBlast_PDB
57.72
31%
7
- C3 -
-
1U0L
1
RSGA_THEMA
A:
[46-299]
-------------------------------------------------------------------------------------------------
N
---
L
---
K
I
Y
V
-
G
D
R
V
E
Y
T
-----
P
D
E
-
T
-----
G
S
G
V
I
E
N
V
L
H
R
K
N
L
L
T
--------
K
P
H
V
A
N
V
D
Q
V
I
L
V
V
T
V
-
K
M
-
P
E
T
S
T
-
Y
I
I
D
K
F
L
V
L
A
E
K
N
E
L
E
T
V
M
V
I
N
K
M
D
L
Y
-
D
E
D
---
D
------
L
--
R
K
--
V
R
E
----
L
-
E
E
I
Y
SGL
Y
P
I
V
K
--
T
--
S
A
-
K
T
--
G
MG
I
E
E
L
K
E
Y
L
----
K
G
K
I
S
T
M
A
G
L
S
G
V
G
K
S
S
L
L
N
A
I
N
P
-
G
L
K
-
L
-
R
-------------
T
T
T
T
A
Q
L
L
K
F
D
F
G
G
Y
V
V
D
T
P
G
F
A
N
L
-
E
I
-
N
D
I
E
P
E
E
L
K
H
Y
F
K
E
F
G
D
K
--
Q
C
F
F
S
D
C
N
H
V
D
E
P
E
C
G
V
K
E
A
V
E
N
G
E
I
A
E
S
R
Y
E
N
Y
V
K
M
F
----
Y
E
L
L
G
R
R
---
22
PsiBlast_CBE
57.53
31%
9
- C3 -
-
1U0L
1
RSGA_THEMA
B:
[46-299]
-------------------------------------------------------------------------------------------------
N
---
L
---
K
I
Y
V
-
G
D
R
V
E
Y
T
-----
P
D
E
-
T
-----
G
S
G
V
I
E
N
V
L
H
R
K
N
L
L
T
--------
K
P
H
V
A
N
V
D
Q
V
I
L
V
V
T
V
-
K
M
-
P
E
T
S
T
-
Y
I
I
D
K
F
L
V
L
A
E
K
N
E
L
E
T
V
M
V
I
N
K
M
D
L
Y
-
D
E
D
---
D
------
L
--
R
K
--
V
R
E
----
L
-
E
E
I
Y
SGL
Y
P
I
V
K
--
T
--
S
A
-
K
T
--
G
MG
I
E
E
L
K
E
Y
L
----
K
G
K
I
S
T
M
A
G
L
S
G
V
G
K
S
S
L
L
N
A
I
N
P
-
G
L
K
-
L
-
R
-------------
T
T
T
T
A
Q
L
L
K
F
D
F
G
G
Y
V
V
D
T
P
G
F
A
N
L
-
E
I
-
N
D
I
E
P
E
E
L
K
H
Y
F
K
E
F
G
D
K
--
Q
C
F
F
S
D
C
N
H
V
D
E
P
E
C
G
V
K
E
A
V
E
N
G
E
I
A
E
S
R
Y
E
N
Y
V
K
M
F
----
Y
E
L
L
G
R
R
---
21
PsiBlast_CBE
55.73
31%
4
- C3 -
-
1U0L
1
RSGA_THEMA
C:
[46-299]
-------------------------------------------------------------------------------------------------
N
---
L
---
K
I
Y
V
-
G
D
R
V
E
Y
T
-----
P
D
E
-
T
-----
G
S
G
V
I
E
N
V
L
H
R
K
N
L
L
T
--------
K
P
H
V
A
N
V
D
Q
V
I
L
V
V
T
V
-
K
M
-
P
E
T
S
T
-
Y
I
I
D
K
F
L
V
L
A
E
K
N
E
L
E
T
V
M
V
I
N
K
M
D
L
Y
-
D
E
D
---
D
------
L
--
R
K
--
V
R
E
----
L
-
E
E
I
Y
SGL
Y
P
I
V
K
--
T
--
S
A
-
K
T
--
G
MG
I
E
E
L
K
E
Y
L
----
K
G
K
I
S
T
M
A
G
L
S
G
V
G
K
S
S
L
L
N
A
I
N
P
-
G
L
K
-
L
-
R
-------------
T
T
T
T
A
Q
L
L
K
F
D
F
G
G
Y
V
V
D
T
P
G
F
A
N
L
-
E
I
-
N
D
I
E
P
E
E
L
K
H
Y
F
K
E
F
G
D
K
--
Q
C
F
F
S
D
C
N
H
V
D
E
P
E
C
G
V
K
E
A
V
E
N
G
E
I
A
E
S
R
Y
E
N
Y
V
K
M
F
----
Y
E
L
L
G
R
R
---
10
PsiBlast_PDB
55.33
33%
-7
- C3 -
-
2YV5
1
RSGA_AQUAE
A:
[44-297]
-----------------------------------------------------------------------------------------------------------
I
Y
A
G
D
Y
V
-
W
G
E
V---
V
D
P
N
T
-----
F
A
--
I
E
E
V
E
E
R
K
N
L
L
I
R
P
K
--------
V
A
N
V
D
-
R
V
I
I
V
E
T
L
K
M
-
P
E
F
N
N
-
Y
L
L
D
N
M
L
V
V
Y
E
Y
F
K
V
E
P
V
I
V
F
N
K
I
D
L
L
-
N
E
E
---
E
-
K
---
K
E
--
L
E
R
W
I
S
I
----
Y
-
R
D
A
G
---
Y
D
V
L
K
--
V
--
S
A
-
K
T
--
G
EG
I
D
E
L
V
D
Y
L
----
E
G
F
I
C
I
L
A
G
P
S
G
V
G
K
S
S
I
L
S
R
L
T
G
-
E
-
E
-
L
-
R
T
Q
E
V
---------
T
T
T
G
V
R
L
I
P
F
G
K
G
S
F
V
G
D
T
P
G
F
S
K
V
E
A
T
-
M
F
V
K
P
R
E
V
R
N
Y
F
R
E
F
L
R
Y
--
Q
C
K
Y
P
D
C
T
H
T
N
E
P
G
C
A
V
K
E
A
V
K
N
G
E
I
S
C
E
R
Y
K
S
Y
L
K
I
I
KVYL
E
E
I
K
E
-----
61
HHSearch
41.74
30%
-12
- C3 -
-
3EC1
1
?
A:
[68-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
E
S
K
A
-
L
V
V
N
I
V
D
I
F
D
-
F
N
G
S
F
I
P
G
L
P
R
F
A
-----
A
D
N
P
I
L
L
V
G
N
K
A
D
L
L
-
P
R
S
VK
Y
P
-
K
---
L
L
--
R
W
--
M
R
R
----
M
A
E
E
L
G
LCP
V
D
V
C
L
--
V
--
S
A
A
K
G
--
I
G-
M
A
K
V
M
E
A
I
N
R
Y
R
E
G
G
D
V
Y
V
V
G
C
T
N
V
G
K
S
T
F
I
N
R
I
I
E
-
E
A
T
-
G
-
K
G
N
V
I
T
--
T
S
Y
F
P
G
T
T
L
D
M
I
E
I
P
L
E
S
G
A
T
L
Y
D
T
P
G
I
I
N
H
-
H
--------------------------------------------------------------------------