@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKS9: (2017-10-29 )
MTQHLSKHRHISFTAHYTGYIWYQMGISHEALATSKGKSLAYLVHPLESWAEKYVGGSMRTTLKQRHTMLDHDLEKLIQENPDLQVLEIACGLSPRGWWFRQHYPSISYRELDLPDMAQAKQNALQQIEKNAPEVLSVDLFTEAFAQAFEVFDSNRPLVVISEGLINYFDKDLLKQLIQSIAHYGASFKKLHYLTDLYPEPVKNKLASIIWNSSKLLKLMSRSSFSFHFKTPLEVKDFFKDAGFSQVNVEQPQIFFGQVSKDSDEEHLGDLVWTIHAQLK
Atome Classification :
(20 SA)
----------------.........10........20...-...-..30........40......-----------------..----50-----.--------.......60....-------....70........80--.-........90....--....100------...-.-.....110..-.....120....---------------------...-----------------------130..------------------------......140...--..-.-.--.--150.-.---.......160.......170.-......180.......190...-....200....-...210.......--------220-----..------....----..230.......240.......250---......---.260..-.....270--........280------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------MTQHLSKHR
H
I
S
F
T
A
H
Y
T
G
Y
I
W
Y
Q-MGI-S
H
E
A
LATSKG
K
S
L
A
Y
L
V
H
P
L
-----------------
E
S
----
W
A
-----
E
--------
K
YVGG
S
M
R
T
T
L
K
Q
-------
R
H
T
M
L
D
H
D
L
E
K
L
I
QE---N-PD
L
Q
V
L
E
I
A
CGLSP--R
G
W
W
F
--------RQH-Y-PSISYRELDL-
P
D
M
A
Q
A
K
Q
N
A
L
Q
---------------------
Q
I
E
-----------------------K-NAP------------------------
E
V
L
S
V
D
L
F
-
T
E
A
--
F
A
-
Q
-
A
--
F
--
E
--
V
-F---DSNR
P
L
V
V
I
S
E
G
L
I
N
Y
F
D
K
D
L
-
L
K
Q
L
I
Q
S
I
A
HYGA
S
F
K
K
L
H
Y
L
T
-DLYP
E
P
V
K
N
K
L
-
A
S
I
IW
N
S
S
K
L
L
K
L
--------
M
S------RS------S
F
S
F
----HFKT
P
L
E
V
K
D
F
F
K
DAGFSQVNVEQP---
Q
I
F
F
GQ---VSKDS
D
-
E
E
H
L
G
D
L
---
V
W
T
I
H
AQLK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
71.27
17%
7
* C5 *
-
1RJD
2
LCMT1_YEAST
C:
[4-295]
-------------------------
I
I
Q
Q
T
D
Y
D
A
L
S
C
K
L
A
-
A
I
--
S
V
G
Y
L
P
S
S
G
L
Q
R
L
S
V
D
L
S
K
K
YTEWHRSYLITLKKFSR
R
A
----
F
G
KVDKA
M
--------
R
S
S
F
P
V
M
N
Y
G
T
Y
L
-------
R
T
V
G
I
D
A
A
I
L
E
F
L
V
A
---
N
-
E
K
V
Q
V
V
N
L
G
C
G
S
D
L
--
R
M
L
P
L
--------
L
Q
M
-
F
-
P
H
L
A
Y
V
D
I
D
Y
-
N
E
S
V
E
L
K
N
S
I
L
R
---------------------
E
S
E
ILRISLGLSKEDTAKSPFLID--
Q
-
G
R
Y
------------------------
K
L
A
A
C
D
L
N
-
D
I
T
--
E
T
-
T
R
L
--
L
D-
V
--
C
-
T
---
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
H
N
N
E
-
S
Q
L
L
I
N
T
I
M
S
K
F
S
--
H
G
L
W
I
S
Y
-
D
P
I
G
G
S
Q
P
N
---
D
R
F
G
A
I
M
Q
S
---
N
--------
L
K
------
E
S
R-----
N
L
E
M
PTLM
T
Y
N
S
K
E
K
Y
A
S
R
W
S
--
A
A
P
N
V
I
V
N
D
M
---
W
E
I
F
N
A
---
Q
I
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
68.42
18%
-38
- C5 -
-
2OB1
-
LCMT1_YEAST
A:
[63-286]
------------------------------------------------------------------------------------------------------------
P
V
M
N
Y
G
T
Y
L
-------
R
T
V
G
I
D
A
A
I
L
E
F
L
V
A
---
N
-
E
K
V
Q
V
V
N
L
G
C
G
S
D
L
--
R
M
L
P
L
--------
L
Q
M
-
F
-
P
H
L
A
Y
V
D
I
D
Y
-
N
E
S
V
E
L
K
N
S
I
L
R
---------------------
E
S
E
I
L
R
I
S
L
GLSKEDTAKSPFLID--
Q
-
G
R
Y
------------------------
K
L
A
A
C
D
L
N
-
D
I
T
--
E
T
T
R
-
L
--
L
D
-
V
--
C
-
T
---
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
H
N
N
E
-
S
Q
L
L
I
N
T
I
M
S
K
F
S
--
H
G
L
W
I
S
Y
-
D
P
I
G
G
S
Q
P
N
---
D
R
F
G
A
I
M
Q
S
---
N
--------
L
K
------
E
S
R-----
N
L
E
M
PTLM
T
Y
N
S
K
E
K
Y
A
S
R
W
S
--
A
A
P
N
V
I
V
N
D
M
---
W
E
I
F
N
A
---
Q
I
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
66.65
17%
15
- C5 -
-
1RJD
2
LCMT1_YEAST
A:
[2-329]
----------E
R
I
I
Q
Q
T
D
Y
D
A
L
S
C
K
L
A
A
I
S
V
G
Y
L
P
S
S
G
L
Q
R
L
S
V
-
D
L
S
K
K
Y
T
E
W
H
R
S
Y
L
I
T
L
K
K
F
-----------------
S
R
----
R
A
-----
F
--------
G
K
V
D
K
A
M
R
S
S
F
P
V
M
N
Y
G
T
Y
L
R
T
V
G
I
D
A
A
I
L
E
F
L
V
A
---
N
-
E
K
V
Q
V
V
N
L
G
C
G
S
D
L
--
R
M
L
P
L
--------
L
Q
M
-
F
-
P
H
L
A
Y
V
D
I
D
Y
-
N
E
S
V
E
L
K
N
S
I
L
R
E
S
E
I
L
R
I
S
L
GLSKEDTAKSPF
L
I
D
-----------------------
Q
-
G
R
Y
------------------------
K
L
A
A
C
D
L
N
-
D
I
T
--
E
T
-
T
-
R
--
L
--
L
D
V
C
-
T
---
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
H
N
N
E
-
S
Q
L
L
I
N
T
I
M
S
K
F
S
H
G
L
W
I
S
Y
D
P
-
I
G
G
S
Q
P
N
D
R
F
G
-
A
I
M
Q
S
N
L
K
E
S
R
N
L
EMPTLMTY
N
S
------
K
E
------
K
Y
A
S
----
R
W
S
A
A
P
N
V
I
V
N
D
M
W
E
I
F
N
A
Q
I
P
E
S
E
---
R
K
R
L
R
S
---
L
Q
F
L
D
E
-
L
E
E
L
K
V
M
Q
T
H
Y
I
L
M
K
A
Q
W
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
65.51
14%
45
- C5 -
-
2ZWA
6
TYW4_YEAST
A:
[16-694]
-------Q
E
R
R
K
K
Y
A
D
L
A
I
Q
G
T
N
N
S
S
I
A
S
K
R
S
V
E
L
L
Y
L
P
K
-
L
S
S
-
A
N
N
F
Q
M
D
K
N
N
K
L
L
E
Y
F
K
F
F
V
-----------------
P
K
----
K
I
-----
K
--------
R
--
S
P
C
I
N
R
G
Y
W
L
-------
R
L
F
A
I
R
S
R
L
N
S
I
I
E
Q
TPQ
D
-
K
K
I
V
V
V
N
L
G
C
G
Y
D
P
--
L
P
F
Q
L
L
DTNNIQS
Q
Q
Y
-
H
-
D
R
V
S
F
I
D
I
D
Y
-
S
D
L
L
K
I
K
I
E
L
I
K
---------------------
T
I
P
-----------------------
E
-
L
S
K
I
I
GLSEDKDYVDDSNVD
F
L
T
T
PK
Y
L
A
R
P
C
D
L
N
D
S
K
M
--
F
S
-
T
-
L
--
L
--
N
--
E
-
C
QLY
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
K
P
E
R
-
S
D
S
I
I
E
A
T
S
K
M
--
E
N
S
H
F
I
I
L
E
-
Q
L
I
P
K
G
P
F
E
P
F
-
S
K
Q
M
L
A
H
F
K
R
N
D
S
--------
P
L
------
Q
S
------
V
L
K
Y
------
N
T
I
E
S
Q
V
Q
R
F
N
K
L
G
F
A
Y
V
N
V
G
D
M
---
F
Q
L
W
E
S
---
A
D
E
A
T
K
-
K
E
L
L
K
V
E
---
P
F
D
E
L
E
E
F
H
L
F
C
H
H
Y
V
L
C
H
A
T
NYKEFAFTQGFLFDRINLTVDED
Y
Q
L
L
E
C
E
C
PINRKF
G
D
V
D
V
AGN
D
V
F
Y
M
G
GSNPYRVN
E
I
L
Q
L
S
I
H
YD
K
I
D
M
K
N
I
E
V
SSSEVPVARMC
H
T
F
T
T
I
SRNN
Q
L
L
L
I
G
GRKAPHQGLS
D
N
W
I
F
D
MKTR
E
W
S
M
I
KSLS
H
T
R
F
R
H
S
A
C
S
L
PDG
N
V
L
I
L
G
GVTEGPA
M
L
L
Y
NVTEEIFKDVTPKDEFFQ
N
S
L
V
S
A
G
L
E
F
D
PVSK
Q
G
I
I
L
G
GGFMDQTTVSDKA
I
I
F
K
Y
D
AENATEPITVI
K
K
L
Q
H
PLFQRYG
S
Q
I
K
Y
ITPR
K
L
L
I
V
G
G
T
S
PS
G
L
F
D
RTNS
I
I
S
L
DPLSE
T
L
T
S
IPIS
R
R
I
W
E
D
H
SLMLAG
F
S
L
V
S
TT
I
H
I
I
G
G
G
A
TCYGF
G
S
V
T
N
V
G
L
K
L
I
A
IA
20
HHSearch
62.83
14%
16
- C5 -
-
2UYO
-
Y2640_MYCLE
A:
[14-309]
--------------------------
V
G
T
T
A
V
M
V
A
A
A
R
A
A
-
E
T
D
R
P
D
A
L
I
R
D
P
Y
A
K
L
L
V
T
N
T
G
A
G
-----------------
A
L
W
E
A
M--------D
A
E
A
----
A
A
M
V
E
H
M
R
S
Y
Q
A
V
-------
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
--------
D
-
W
-
P
-
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
L
A
---------------------
E
H
G
VTP--------------------
T
-
A
D
R
------------------------
R
E
V
P
I
D
L
R
-
Q
-
D
--
W
P
-
P
-
A
--
L
R
S
A
--
G
-
F
---
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
A
-
Q
D
G
L
F
T
E
I
G
G
L
S
A
--
V
G
S
R
I
A
V
-
E
T
S
P
L
H
G
D
-
E
W
-
R
E
Q
M
Q
L
R
F
R
R
V
S
D
--------
A
----------------
E
L
I
Y---
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
-
R
---
W
G
D
G
V
P
M
A
D
D
K
D
A
F
---
A
E
F
V
T
A
H
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
62.28
14%
11
- C5 -
-
2CKD
-
Y2640_MYCLE
A:
[8-309]
--------------------
W
D
I
K
T
S
V
G
T
T
A
V
M
V
A
A
A
R
A
A
-
E
T
D
R
P
D
A
L
I
R
D
P
Y
A
K
L
L
V
T
N
T
G
A
G
-----------------
A
L
W
E
A
M
L
D
PSM
V
A
K
V
E
A
I
D
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
-------
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
--------
D
-
W
-
P
-
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
L
A
---------------------
E
H
G
VTP--------------------
T
-
A
D
R
------------------------
R
E
V
P
I
D
L
R
-
Q
-
D
--
W
P
-
P
-
A
--
L
R
S
A
--
G
-
F
---
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
A
-
Q
D
G
L
F
T
E
I
G
G
L
S
A
--
V
G
S
R
I
A
V
-
E
T
S
P
L
H
G
D
-
E
W
-
R
E
Q
M
Q
L
R
F
R
R
V
S
D
--------
A
L
GFE
Q
A
V
D
V
------
Q
E
L
I
Y---
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
-
R
---
W
G
D
G
V
P
M
A
D
D
K
D
A
F
---
A
E
F
V
T
A
H
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
57.95
14%
-51
- C5 -
-
4QDJ
1
CHLM_SYNY3
A:
[2-230]
----------------
T
N
A
A
L
D
D
K
T
I
V
R
D
Y
F
N
S
T
G
F
D
R
W
R
-
R
I
Y
-
G
D
G
Q
V
---------------------------------
N
----
F
V
-----
Q
--------
K
D
I
R
V
G
H
Q
Q
T
V
D
S
-------
V
V
A
W
L
V
A
D
-----
G
N
---
L
-
P
G
L
L
V
C
D
A
G
C
G
V
G
S
--
L
S
I
P
L
--------
A
Q
A
-
G
-
A
L
V
Y
G
S
D
I
S
E
-
K
M
V
G
E
A
Q
Q
K
A
Q
E
---------------------
V
L
A
-----------------------
Y
G
N
Q
P
------------------------
T
F
M
T
Q
D
L
A
-
Q
L
G
------------------------
G
K
Y
D
T
V
I
C
L
D
V
L
I
H
Y
P
T
E
E
-
A
S
A
M
I
S
H
L
A
S
L
----------------------------
A
D
R
R
L
I
L
S
F
--------
A
P
------
K
R
------
A
Y
Q
-------
H
K
E
A
D
I
R
K
I
L
G
D
N
G
F
S
I
A
R
T
G
M
T
---
S
T
R
F
--------------
Y
Y
S
R
I
---
L
E
A
V
R
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
57.28
12%
-16
- C5 -
-
3O7W
1
LCMT1_HUMAN
A:
[13-247]
-----------------------------
T
C
E
D
A
S
L
C
K
R
F
-
A
V
--
S
I
G
Y
W
H
D
P
Y
I
Q
H
F
V
R
L
S
K
E
R
---------------------------------------
K
--
A
P
E
I
N
R
G
Y
F
A
-------
R
V
H
G
V
S
Q
L
I
K
A
F
L
R
K
---
T
E
C
H
C
Q
I
V
N
L
G
A
G
M
D
T
--
T
F
W
R
L
--------
K
D
E
-
D
L
L
P
S
K
Y
F
E
V
D
F
-
P
M
I
V
T
R
K
L
H
S
I
K
---------------------
C
K
P
PLS
S
P
I
L
E
L
HSEDTLQMDGH
I
L
D
S
-
K
R
Y
------------------------
A
V
I
G
A
D
L
R
-
D
L
S
E
-
L
E
-
E
-
K
--
L
K
K
C
--
N
-
M
---
N
T
Q
L
P
T
L
L
I
A
E
C
V
L
V
Y
M
T
P
E
Q
-
S
A
N
L
L
K
W
A
A
N
S
F
---
E
R
A
M
F
I
N
Y
E
Q
V
N
E
G
-----------------------------------------------------
K
S
L
E
S
Q
K
E
R
L
L
S
N
G
W
E
T
A
S
A
V
D
M
---
M
E
L
Y
N
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
56.63
11%
-29
- C5 -
-
3IEI
3
LCMT1_HUMAN
B:
[25-288]
-------------------------
G
V
R
G
T
C
E
D
A
S
L
C
K
R
F
-
A
V
--
S
I
G
Y
W
H
D
P
Y
I
Q
H
F
V
R
L
S
K
E
R
------------------
K
-----------------------
A
P
E
I
N
R
G
Y
F
A
-------
R
V
H
G
V
S
Q
L
I
K
A
F
L
R
K
---
T
E
C
H
C
Q
I
V
N
L
G
A
G
M
D
T
--
T
F
W
R
L
--------
K
D
E
-
D
L
L
S
S
K
Y
F
E
V
D
F
-
P
M
I
V
T
R
K
L
H
S
I
K
---------------------
C
K
P
PLSSPILELHSEDTLQMDGHILD
S
-
K
R
Y
------------------------
A
V
I
G
A
D
L
R
-
D
L
S
E-
L
E
-
E
-
K
--
L
KK
C
--
N
-
M
---
N
T
Q
L
P
T
L
L
I
A
E
C
V
L
V
Y
M
T
P
E
Q
-
S
A
N
L
L
K
W
A
A
N
S
F
E
--
R
A
M
F
I
N
Y
-
E
Q
V
N
M
G
D
R
------
F
G
Q
I
M
I
E
---
N
--------
L
R
------
R
R
------
Q
C
D
L
AGVE
T
C
K
S
L
E
S
Q
K
E
R
L
L
S
N
G
W
E
T
A
S
A
V
D
M
---
M
E
L
Y
N
R
---
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
55.19
16%
-24
- C5 -
-
3MCZ
-
?
B:
[179-336]
------------------------------------------------------------------------------------------------------------------------------------------------
R
A
R
T
V
I
D
L
A
G
G
H
G
T
--
Y
L
A
Q
V
--------
L
R
R
-
H
-
P
Q
L
T
G
Q
I
W
D
L
-
P
T
T
R
D
A
A
R
K
T
I
H
---------------------
A
H
D
L----------------------
G
-
G
R
V
------------------------
E
F
F
E
K
N
L
L
-
D
A
R
----------------
N
-
F
---
E
G
G
A
A
D
V
V
M
L
N
D
C
L
H
Y
F
D
A
R
E
-
A
R
E
V
I
G
H
A
A
G
L
V
K
--
P
G
G
A
L
L
I
L
T
M
T
M
N
D
D
R
V
T
P
-
A
-
L
S
-
A
D
F
S
L
H
-
M
--------
M
V
------
N
-------
T
N
H
G
----
E
L
H
P
T
P
W
I
A
G
V
V
R
D
A
G
L
A
V
G
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
55.04
13%
37
- C5 -
-
2CKD
-
Y2640_MYCLE
A:
[8-310]
WDIKT
S
V
G
T
T
A
V
M
V
A
A
A
R
A
A
E
T
D
R
P
D
A
L
I
R
D
P
Y
A
K
L
L
V
T
N
-
T
G
A
-
G
A
L
W
E
A
M
L
D
P
S
M
V
A
K
V
E
A
I
D
-----------------
A
E
----
A
A
-----
A
--------
M
V
E
H
--
M
R
S
Y
Q
A
V
-------
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
D
---
G
-
I
R
-
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
--------
D
W
P
---
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
L
A
---------------------
E
H
G
-----------------------
V
-
T
P
T
ADR---------------------
R
E
V
P
I
D
L
R
-
Q
D
W
--
P
P
-
A
-
L
--
R
--
S
--
A
G
F
---
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
P
A
T
A
-
Q
D
G
L
F
T
E
I
G
G
L
S
A
--
V
G
S
R
I
A
V
-
E
T
S
P
L
H
G
D
E
W
R
-
E
Q
M
Q
L
R
F
R
R
V
S
D
A
--------
L
G
------
F
E
Q
A
V
D
V
Q
E
L
I
Y
----
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
---
D
E
M
R
R
V
GRW
G
D
G
V
P
M
-
A
D
D
K
D
A
F
---
A
E
F
V
T
A
H
R
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
53.26
16%
-27
- C5 -
-
3MCZ
1
?
A:
[179-336]
------------------------------------------------------------------------------------------------------------------------------------------------
R
A
R
T
V
I
D
L
A
G
G
H
G
T
--
Y
L
A
Q
V
--------
L
R
R
-
H
-
P
Q
L
T
G
Q
I
W
D
L
-
P
T
T
R
D
A
A
R
K
T
I
H
---------------------
A
H
D
L----------------------
G
-
G
R
V
------------------------
E
F
F
E
K
N
L
L
-
D
A
R
----------------
N
-
F
---
E
G
G
A
A
D
V
V
M
L
N
D
C
L
H
Y
F
D
A
R
E
-
A
R
E
V
I
G
H
A
A
G
L
V
K
--
P
G
G
A
L
L
I
L
T
M
T
M
N
D
D
R
V
T
P
-
A
-
L
S
-
A
D
F
S
L
H
-
M
--------
M
V
------
N
-------
T
N
H
G
----
E
L
H
P
T
P
W
I
A
G
V
V
R
D
A
G
L
A
V
G
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
52.33
12%
-43
- C5 -
-
4U1Q
2
?
C:
[170-331]
------------------------------------------------------------------------------------------------------------------------------------------------
R
V
H
R
V
L
D
V
G
G
G
D
A
V
--
N
A
V
A
L
--------
A
R
A
-
H
-
P
S
L
R
V
T
V
L
D
R
-
P
G
A
L
E
V
A
R
K
T
I
A
---------------------
E
A
G
L----------------------
E
-
E
R
V
------------------------
R
T
H
A
A
D
I
F
-
T
D
S
--
Y
-------
P
--
A
--
G
-
H
--------
D
C
V
L
F
A
H
Q
L
V
I
W
S
P
E
Q
-
N
L
T
L
L
R
K
A
Y
D
A
V
E
--
P
G
G
R
V
L
V
F
N
A
F
T
D
D
D
R
T
G
---
P
L
Y
A
A
L
D
N
V
Y
-
F
--------
T
T
------
L
P
------
F
R
H
S
----
T
I
H
R
W
A
D
C
E
S
W
L
R
E
A
G
F
T
D
V
G
R
T
A
P
---
P
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
51.28
12%
-43
- C5 -
-
4QVG
-
?
C:
[170-331]
------------------------------------------------------------------------------------------------------------------------------------------------
R
V
H
R
V
L
D
V
G
G
G
D
A
V
--
N
A
V
A
L
--------
A
R
A
-
H
-
P
S
L
R
V
T
V
L
D
R
-
P
G
A
L
E
V
A
R
K
T
I
A
---------------------
E
A
G
L----------------------
E
-
E
R
V
------------------------
R
T
H
A
A
D
I
F
-
T
D
S
--
Y
-------
P
--
A
--
G
-
H
--------
D
C
V
L
F
A
H
Q
L
V
I
W
S
P
E
Q
-
N
L
T
L
L
R
K
A
Y
D
A
V
E
--
P
G
G
R
V
L
V
F
N
A
F
T
D
D
D
R
T
G
---
P
L
Y
A
A
L
D
N
V
Y
-
F
--------
T
T
------
L
P
------
F
R
H
S
----
T
I
H
R
W
A
D
C
E
S
W
L
R
E
A
G
F
T
D
V
G
R
T
A
P
---
P
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
50.92
12%
-99
- C5 -
-
4A6D
-
ASMT_HUMAN
A:
[179-334]
------------------------------------------------------------------------------------------------------------------------------------------------
V
F
P
L
M
C
D
L
G
G
G
A
G
A
--
L
A
K
E
C
--------
M
S
L
-
Y
-
P
G
C
K
I
T
V
F
D
I
-
P
E
V
V
W
T
A
K
Q
H
F
S
---------------------
F
-------------------------
E
-
E
Q
I
------------------------
D
F
Q
E
G
D
F
F
-
K
D
P
----------
L
--
P
--
E
-
A
--------
D
L
Y
I
L
A
R
V
L
H
D
W
A
D
G
K
-
C
S
H
L
L
E
R
I
Y
H
T
C
K
--
P
G
G
G
I
L
V
I
E
S
L
L
D
E
D
R
R
G
P
---
L
L
T
Q
L
Y
S
L
N
-
M
--------
L
V
------
Q
T
------
E
--
G
----
Q
E
R
T
P
T
H
Y
H
M
L
L
S
S
A
G
F
R
D
F
Q
F
K
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
49.89
13%
-9
- C5 -
-
3GIW
3
?
A:
[55-244]
--------------------------------------------------------------------------------------------------------------
L
P
V
H
M
R
A
-------
N
R
D
W
M
N
R
A
V
A
H
L
A
K
E
---
A
-
G
I
R
Q
F
L
D
I
G
T
G
I
P
T
SP
N
L
H
E
I
--------
A
Q
S
V
A
-
P
E
S
R
V
V
Y
V
D
N
D
P
I
V
L
T
L
S
Q
G
L
L
A
---------------------
S
T
P
-----------------------
E
-
G
R
T
------------------------
A
Y
V
E
A
D
M
L
-
D
P
A
S
I
L
D
-
A
-
P
E
L
R
--
D
--
T
-
L
---
D
L
T
R
P
V
A
L
T
V
I
A
I
V
H
F
V
L
D
E
D
D
A
V
G
I
V
R
R
L
L
E
P
L
P
--
S
G
S
Y
L
A
M
-
S
I
G
T
A
E
F
A
P
Q
E
-
V
---
G
R
V
A
R
---
E
--------
Y
A
------
A
R
------
N
M
P
M
----
R
L
R
T
H
A
E
A
E
E
F
F
--
E
G
L
E
L
V
E
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
49.43
12%
-94
- C5 -
-
4A6E
1
ASMT_HUMAN
A:
[179-334]
------------------------------------------------------------------------------------------------------------------------------------------------
V
F
P
L
M
C
D
L
G
G
G
A
G
A
--
L
A
K
E
C
--------
M
S
L
-
Y
-
P
G
C
K
I
T
V
F
D
I
-
P
E
V
V
W
T
A
K
Q
H
F
S
---------------------
F
-------------------------
E
-
E
Q
I
------------------------
D
F
Q
E
G
D
F
F
-
K
D
P
----------
L
--
P
--
E
-
A
--------
D
L
Y
I
L
A
R
V
L
H
D
W
A
D
G
K
-
C
S
H
L
L
E
R
I
Y
H
T
C
K
--
P
G
G
G
I
L
V
I
E
S
L
L
D
E
D
R
R
G
P
---
L
L
T
Q
L
Y
S
L
N
-
M
--------
L
V
------
Q
T
------
E
--
G
----
Q
E
R
T
P
T
H
Y
H
M
L
L
S
S
A
G
F
R
D
F
Q
F
K
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
49.06
12%
-107
- C5 -
-
3P9C
1
?
A:
[201-353]
------------------------------------------------------------------------------------------------------------------------------------------------
G
L
G
T
L
V
D
V
G
G
G
V
G
A
--
T
V
A
A
I
--------
A
A
H
-
Y
-
P
T
I
K
G
V
N
F
D
L
-
P
H
V
I
S
E
A
P
Q
F
---------------------------------------------------
P
G
V
------------------------
T
H
V
G
G
D
M
F
-
K
E
V
-------------
P
--
S
-
G
--------
D
T
I
L
M
K
W
I
L
H
D
W
S
D
Q
H
-
C
A
T
L
L
K
N
C
Y
D
A
L
P
--
A
H
G
K
V
V
L
V
Q
C
I
L
P
V
N
P
E
A
N
P
S
S
Q
G
V
F
H
V
D
M
I
-
M
--------
L
A
------
H
N
-------
P
G
G
----
R
E
R
Y
E
R
E
F
Q
A
L
A
R
G
A
G
F
T
G
V
K
S
T
Y
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
47.89
15%
-19
- C5 -
-
3GWZ
2
MMCR_STRLA
C:
[202-355]
------------------------------------------------------------------------------------------------------------------------------------------------
G
A
A
T
A
V
D
I
G
G
G
R
G
S
--
L
M
A
A
V
--------
L
D
A
-
F
-
P
G
L
R
G
T
L
L
E
R
-
P
P
V
A
E
E
A
R
E
L
L
T
---------------------
G
R
G
L----------------------
A
-
D
R
C
------------------------
E
I
L
P
G
D
F
F
-
E
T
I
-----------------------
P
D
G
A
D
V
Y
L
I
K
H
V
L
H
D
W
D
D
D
D
-
V
V
R
I
L
R
R
I
A
T
A
M
K
--
P
D
S
R
L
L
V
I
D
N
L
I
D
E
R
P
A
A
S
-
T
-
L
---
F
V
D
L
L
L
L
--------
V
L
------
V
G
------
G
-------
A
E
R
S
E
S
E
F
A
A
L
L
E
K
S
G
L
R
V
E
R
S
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
47.01
15%
-22
- C5 -
-
5I2H
5
?
A:
[196-352]
------------------------------------------------------------------------------------------------------------------------------------------------
S
G
R
V
L
L
D
V
A
G
G
S
G
I
--
Y
T
M
A
V
--------
L
Q
K
-
Y
-
P
T
W
R
G
I
I
F
D
R
-
P
E
V
L
K
I
A
A
E
L
A
E
---------------------
Q
T
G
V----------------------
R
-
D
R
L
------------------------
E
L
H
A
G
D
M
W
-
V
D
P
----------
F
--
P
--
P
-
A
---
D
-----
D
I
L
L
S
N
V
L
H
D
W
D
R
P
Q
-
C
A
R
L
V
A
K
A
T
S
G
L
P
--
E
G
G
R
L
L
I
H
D
V
L
L
N
S
D
L
T
G
P
-
L
--
E
I
A
L
Y
S
-
L
A
L
--------
F
S
------
L
T
--------
E
G
----
R
A
Y
S
L
E
E
Y
R
G
W
I
A
G
A
D
L
K
Y
V
D
C
I
P
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------