@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKT1: (2017-10-29 )
MQDSIEQYMQKVGQQARDASRVLTSASTSLKNHALSAIYTALENNQAAILAANQIDMEKGRSNQLDSALLDRLELTPARFKGMLQGLKDVIALVDPIGEITDLAYRPTGIQIGKMRVPLGVVGMIYESRPNVTLEAASLAIKSGNAIILRGGSEALESNKAIAEAVKHGLKVAGLPEHSVQVIETSDRAAVGHLITMAEYVDVIVPRGGKSLIERVTNEARIPVIKHLDGNCHVFVEAQADLQKALPITLNAKTHRYGVCNAMETLLVDEKIAEVFLPHIAELYAEKQVELRGCPETHRILGTTVKPATEEDWYTEYLGPILAVKVVSGIDEAIDHINKYGSHHTDAIVTENYTLARQFLARVDSSSVVVNASTRFADGFEYGLGAEIGISTDKIHARGPVGLEGLTSQKWIVLGDGQIRQ
Atome Classification :
(20 SA)
.........10........20--........30........40...-------.....50........60........70.....-..-.80.-.......90...-.-.-.-..100.......110.......120.......-130-........140.......150....----...160....-...170--.........180.......190.-......200.......210......---.---------220--........-230.......240.......250....-...260.......270...-.----------------...280.......290...-----------------.-----------------..--------.300.--------------------.------------------------...----.-------..310.......320......--.330.......340.......350.......360.......370......--.380.......390.....-..400.......410.......420
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
Q
D
S
I
E
Q
Y
M
Q
K
V
G
Q
Q
A
R
D
A
S
R
--
V
L
T
S
AS
T
S
L
K
N
H
A
L
S
A
I
Y
T
A
LEN-------N
Q
A
A
I
L
A
A
N
Q
I
D
M
EKGRSN
Q
L
D
S
A
L
L
D
R
LEL
T
-
P
A
-
R
F
K
G
-
M
L
Q
G
L
K
D
V
I
A
L
V-D-
P
-
I
-
G
E
I
T
DLAYRPTG
I
Q
IG
K
M
RVP
L
G
V
V
G
M
I
YESR-P-
N
-
V
T
L
E
A
A
S
L
A
IKSG
N
A
I
I
LRG
G
S
E
A
L
----ES
N
K
A
I
A
E
A
V
-KHG
L
----
K
VAGLPEH
S
V
Q
V
I
ETSD
R
A
A
V
G
H
-
L
I
T
M
A
E
Y
V
D
V
IVPRG
G
K
S
L
I
E
R
V
TN---E---------AR---I
P
V
I
KHLD-GN
C
H
V
F
V
E
AQA
D
L
Q
KA
L
P
I
T
LNAKTHR-Y
G
V
C
N
A
M
E
T
L
L
V
D
E
K
I
A
E
V
-
F
----------------
L
P
H
I
A
E
L
Y
A
E
K
Q
V
E
LRGCP-----------------
E
-----------------
T
H
--------
R
I
L-G--------------------T------------------------TVK----P-------ATE
E
D
W
Y
T
E
Y
L
G
P
I
L
A
V
K
V
V
S
--
G
I
D
E
A
I
D
H
I
N
K
YGSHHT
D
A
I
VTE
N
Y
T
L
A
R
Q
F
L
A
RVDSS
S
V
V
V
NASTRFAD--GFEYGLGAEIGISTD
K
I
HA-RGPVGLEGLTSQ
K
W
I
V
LGDGQIRQ
2
PsiBlast_PDB
85.53
49%
-97
- C- -
-
1O20
-
PROA_THEMA
A:
[8-415]
------------
A
K
K
V
R
E
A
W
D
--
V
L
R
N
A
T
T
R
E
K
N
K
A
I
K
K
I
A
E
K
L
D
E
-------
R
R
K
E
I
L
E
A
N
R
I
D
V
E
K
A
R
E
R
G
V
K
E
S
L
V
D
R
L
A
L
N
-
D
K
-
R
I
D
E
-
M
I
K
A
C
E
T
V
I
G
L
K
-
D
-
P
-
V
-
G
E
V
I
D
S
W
V
R
E
D
G
L
R
I
A
R
V
R
V
P
I
G
P
I
G
I
I
Y
E
S
R
-
P
-
N
-
V
T
V
E
T
T
I
L
A
L
K
S
G
N
T
I
L
L
R
G
G
S
D
A
L
----
N
S
N
K
A
I
V
S
A
I
-
R
E
A
L
----
K
E
T
E
I
P
E
S
S
V
E
F
I
E
N
T
D
R
S
L
V
L
E
-
M
I
R
L
R
E
Y
L
S
L
V
I
P
R
G
G
Y
G
L
I
S
F
V
R
D
---
N
---------
A
T
---
V
P
V
L
E
T
G
V
-
G
N
C
H
I
F
V
D
E
S
A
D
L
K
K
A
V
P
V
I
I
N
A
K
T
Q
R
-
P
G
T
C
N
A
A
E
K
L
L
V
H
E
K
I
A
K
E
-
F
----------------
L
P
V
I
V
E
E
L
R
K
H
G
V
E
V
R
G
C
E
-----------------
K
-----------------
T
R
--------
E
I
V
-
P
--------------------
D
------------------------
V
V
-----
P
-------
A
T
E
D
D
W
P
T
E
Y
L
D
L
I
I
A
I
K
V
V
K
--
N
V
D
E
A
I
E
H
I
K
K
Y
S
T
G
H
S
E
S
I
L
T
E
N
Y
S
N
A
K
K
F
V
S
E
I
D
A
A
A
V
Y
V
N
A
S
T
R
F
T
D
--
G
G
Q
F
G
F
G
A
E
I
G
I
S
T
Q
R
F
H
A
-
R
G
P
V
G
L
R
E
L
T
T
Y
K
F
V
V
L
G
E
Y
H
V
R
E
53
HHSearch
84.72
63%
-
- C- -
-
4GHK
-
PROA_BURTA
B:
[2-422]
---
D
I
D
Q
Y
M
T
D
V
G
R
R
A
R
R
A
S
R
--
S
I
A
R
A
S
T
A
A
K
N
A
A
L
E
A
V
A
R
A
I
E
R
-------
D
A
G
A
L
K
A
A
N
A
R
D
V
A
R
A
K
D
K
G
L
D
A
A
F
V
D
R
L
T
L
S
-
D
K
-
A
L
K
T
-
M
V
E
G
L
R
Q
V
A
T
L
P
-
D
-
P
-
I
-
G
E
M
S
N
L
K
Y
R
P
S
G
I
Q
V
G
Q
M
R
V
P
L
G
V
I
G
I
I
Y
E
S
R
-
P
-
N
-
V
T
I
D
A
A
A
L
C
L
K
S
G
N
A
T
I
L
R
G
G
S
E
A
L
----
E
S
N
T
A
L
A
K
L
I
-
G
E
G
L
----
A
E
A
G
L
P
Q
D
T
V
Q
V
V
E
T
A
D
R
A
A
V
G
R
-
L
I
T
M
T
E
Y
V
D
V
I
V
P
R
G
G
K
S
L
I
E
R
L
I
N
---
E
---------
A
R
---
V
P
M
I
K
H
L
D
-
G
I
C
H
V
Y
V
D
D
R
A
S
V
T
K
A
L
T
V
C
D
N
---------
C
N
T
M
E
T
L
L
V
A
R
G
I
A
P
A
-
V
----------------
L
S
P
L
G
R
L
Y
R
E
K
G
V
E
L
R
V
D
A
-----------------
D
-----------------
A
R
--------
A
V
L
-
E
--------------------
A
A
-----------------------
G
V
G
----
P
L
V
D
----
A
T
D
E
D
W
R
T
E
---
P
V
L
A
I
K
I
V
D
--
G
I
D
A
A
I
E
H
I
N
E
Y
G
S
H
H
T
D
A
I
V
T
E
D
H
D
R
A
M
R
F
L
R
E
V
D
S
A
S
V
M
V
N
A
S
T
R
F
A
D
--
G
F
E
F
G
L
G
A
E
I
G
I
S
N
D
K
L
H
A
-
R
G
P
V
G
L
E
G
L
T
S
L
K
Y
V
V
L
G
H
G
E
G
R
-
54
HHSearch
82.69
63%
-
- C- -
-
4GHK
-
PROA_BURTA
D:
[3-422]
----
I
D
Q
Y
M
T
D
V
G
R
R
A
R
R
A
S
R
--
S
I
A
R
A
S
T
A
A
K
N
A
A
L
E
A
V
A
R
A
I
E
R
-------
D
A
G
A
L
K
A
A
N
A
R
D
V
A
R
A
K
D
K
-----
F
V
D
R
L
T
L
S
-
D
K
-
A
L
K
T
-
M
V
E
G
L
R
Q
V
A
T
L
P
-
D
-
P
-
I
-
G
E
M
S
N
L
K
Y
R
P
S
G
I
Q
V
G
Q
M
R
V
P
L
G
V
I
G
I
I
Y
E
S
R
-
P
-
N
-
V
T
I
D
A
A
A
L
C
L
K
S
G
N
A
T
I
L
R
G
G
S
E
A
L
----
E
S
N
T
A
L
A
K
L
I
-
G
E
G
L
----
A
E
A
G
L
P
Q
D
T
V
Q
V
V
E
T
A
D
R
A
A
V
G
R
-
L
I
T
M
T
E
Y
V
D
V
I
V
P
R
G
G
K
S
L
I
E
R
L
I
N
---
E
---------
A
R
---
V
P
M
I
K
H
L
D
-
G
I
C
H
V
Y
V
D
D
R
A
S
V
T
K
A
L
T
V
C
D
----------
C
N
T
M
E
T
L
L
V
A
R
G
I
A
P
A
-
V
----------------
L
S
P
L
G
R
L
Y
R
E
K
G
V
E
L
R
V
D
A
-----------------
D
-----------------
A
R
--------
A
V
L
-
E
--------------------
A
A
-----------------------
G
V
G
----
P
L
V
D
----
A
T
D
E
D
W
------
P
V
L
A
I
K
I
V
D
--
G
I
D
A
A
I
E
H
I
N
E
Y
G
S
H
H
T
D
A
I
V
T
E
D
H
D
R
A
M
R
F
L
R
E
V
D
S
A
S
V
M
V
N
A
S
T
R
F
A
D
--
G
F
E
F
G
L
G
A
E
I
G
I
S
N
D
K
L
H
A
-
R
G
P
V
G
L
E
G
L
T
S
L
K
Y
V
V
L
G
H
G
E
G
R
-
66
HHSearch
79.42
48%
-42
- C- -
-
1O20
-
PROA_THEMA
A:
[2-414]
------
D
E
L
L
E
K
A
K
K
V
R
E
A
W
D
--
V
L
R
N
A
T
T
R
E
K
N
K
A
I
K
K
I
A
E
K
L
D
E
-------
R
R
K
E
I
L
E
A
N
R
I
D
V
E
K
A
R
E
R
G
V
K
E
S
L
V
D
R
L
A
L
N
-
D
K
-
R
I
D
E
-
M
I
K
A
C
E
T
V
I
G
L
K
-
D
-
P
-
V
-
G
E
V
I
D
S
W
V
R
E
D
G
L
R
I
A
R
V
R
V
P
I
G
P
I
G
I
I
Y
E
S
R
-
P
-
N
-
V
T
V
E
T
T
I
L
A
L
K
S
G
N
T
I
L
L
R
G
G
S
D
A
L
----
N
S
N
K
A
I
V
S
A
I
-
R
E
A
L
----
K
E
T
E
I
P
E
S
S
V
E
F
I
E
N
T
D
R
S
L
V
L
E
-
M
I
R
L
R
E
Y
L
S
L
V
I
P
R
G
G
Y
G
L
I
S
F
V
R
D
-------------
N
A
---
T
V
P
V
L
E
T
G
V
G
N
C
H
I
F
V
D
E
S
A
D
L
K
K
A
V
P
V
I
I
N
A
K
T
Q
R
-
P
G
T
C
N
A
A
E
K
L
L
V
H
E
K
I
A
K
E
-
F
----------------
L
P
V
I
V
E
E
L
R
K
H
G
V
E
V
R
G
C
E
-----------------
K
-----------------
T
R
---------
E
I
-
V
--------------------
P
------------------------
D
V
V
----
P
-------
A
T
E
D
D
W
P
T
E
Y
L
D
L
I
I
A
I
K
V
V
K
--
N
V
D
E
A
I
E
H
I
K
K
Y
S
T
G
H
S
E
S
I
L
T
E
N
Y
S
N
A
K
K
F
V
S
E
I
D
A
A
A
V
Y
V
N
A
S
T
R
F
T
D
GG
Q
F
G
F
G
A
--
E
I
G
I
S
T
Q
R
F
H
A
-
R
G
P
V
G
L
R
E
L
T
T
Y
K
F
V
V
L
G
E
Y
H
V
R
-
73
Fugue
78.89
49%
5
- C- -
-
1O20
-
PROA_THEMA
A:
[2-415]
------
D
E
L
L
E
K
A
K
K
V
R
E
A
W
D
--
V
L
R
N
A
T
T
R
E
K
N
K
A
I
K
K
I
A
E
K
L
D
E
-------
R
R
K
E
I
L
E
A
N
R
I
D
V
E
K
A
R
E
R
G
V
K
E
S
L
V
D
R
L
A
L
N
-
D
K
-
R
I
D
E
M
I
-
K
A
C
E
T
V
I
G
L
K
-
D
-
P
-
V
-
G
E
V
I
D
S
W
V
R
E
D
G
L
R
I
A
R
V
R
V
P
I
G
P
I
G
I
I
Y
E
S
R
-
P
-
N
-
V
T
V
E
T
T
I
L
A
L
K
S
G
N
T
I
L
L
R
G
G
S
D
A
L
----
N
S
N
K
A
I
V
S
A
I
-
R
E
A
L
----
K
E
T
E
I
P
E
S
S
V
E
F
I
E
N
T
D
R
S
L
V
L
E
M
I
-
R
L
R
E
Y
L
S
L
V
I
P
R
G
G
Y
G
L
I
S
F
V
R
D
---
N
---------
A
T
---
V
P
V
L
E
T
G
V
-
G
N
C
H
I
F
V
D
E
S
A
D
L
K
K
A
V
P
V
I
I
N
A
K
T
Q
R
-
P
G
T
C
N
A
A
E
K
L
L
V
H
E
K
I
A
K
E
-
F
----------------
L
P
V
I
V
E
E
L
R
K
H
G
V
E
V
R
G
C
E
-----------------
K
-----------------
T
R
--------
E
I
V
-
P
--------------------
D
-------------------------
V
V
----
P
-------
A
T
E
D
D
W
P
T
E
Y
L
D
L
I
I
A
I
K
V
V
K
--
N
V
D
E
A
I
E
H
I
K
K
Y
S
T
G
H
S
E
S
I
L
T
E
N
Y
S
N
A
K
K
F
V
S
E
I
D
A
A
A
V
Y
V
N
A
S
T
R
F
T
D
--
G
G
Q
F
G
F
G
A
E
I
G
I
S
T
Q
R
F
H
A
-
R
G
P
V
G
L
R
E
L
T
T
Y
K
F
V
V
L
G
E
Y
H
V
R
E
59
HHSearch
69.98
35%
-18
- C3 -
-
2H5G
-
P5CS_HUMAN
B:
[30-437]
-------
T
V
E
Q
Q
G
E
M
A
R
S
G
G
R
--
M
L
A
T
L
E
P
E
Q
R
A
E
I
I
H
H
L
A
D
L
L
T
D
-------
Q
R
D
E
I
L
L
A
N
K
K
D
L
E
E
A
E
G
R
-
L
A
A
P
L
L
K
R
L
S
L
S
-
T
S
-
K
L
N
S
-
L
A
I
G
L
R
Q
I
A
A
S
S
Q
D
-
S
-
V
-
G
R
V
L
R
R
T
R
I
A
K
N
L
E
L
E
Q
V
T
V
P
I
G
V
L
L
V
I
F
E
S
R
-
P
-
D
-
C
L
P
Q
V
A
A
L
A
I
A
S
G
N
G
L
L
L
K
G
G
K
E
A
A
----
H
S
N
R
I
L
H
L
L
T
-
Q
E
A
L
----
S
I
H
G
V
K
-
E
A
V
Q
L
V
N
T
-
R
-
E
E
V
E
-----
L
D
K
M
I
D
L
I
I
P
R
G
S
S
Q
L
V
R
D
I
Q
K
---
A
A--------
K
G
---
I
P
V
M
G
H
S
E
-
G
I
C
H
M
Y
V
D
S
E
A
S
V
D
K
V
T
R
L
V
R
D
S
K
C
E
Y
-
P
A
A
C
N
A
L
E
T
L
L
I
H
R
D
L
L
R
T
P
L
----------------
F
D
Q
I
I
D
M
L
R
V
E
Q
V
K
I
H
A
G
P
-----------------
K
-----------------
F
A
--------
S
Y
L
-----------------------------------------------
T
F
---------------
V
K
S
L
R
T
E
Y
G
D
L
E
L
C
I
E
V
V
D
--
N
V
Q
D
A
I
D
H
I
H
K
Y
G
S
S
H
T
D
V
I
V
T
E
D
E
N
T
A
E
F
F
L
Q
H
V
D
S
A
C
V
F
W
N
A
S
T
R
F
S
D
--
G
Y
R
F
G
L
G
A
E
V
G
I
S
T
S
R
I
H
A
-
R
G
P
V
G
L
E
G
L
L
T
T
K
W
L
L
R
G
K
D
H
---
4
PsiBlast_PDB
66.76
30%
-4
- C3 -
-
4JBE
3
?
A:
[35-441]
---------
N
E
V
A
K
A
V
E
E
C
A
R
--
A
A
K
S
A
A
P
S
L
S
G
A
P
D
T
A
I
D
A
A
L
E
S
M
A
D
R
L
L
A
H
R
D
A
V
L
A
A
N
A
E
D
I
A
K
A
E
A
G
G
M
S
A
G
L
L
D
R
L
T
I
T
-
E
S
-
R
L
T
D
-
M
A
D
Q
L
R
L
L
A
G
A
P
-
H
-
P
---
Q
R
T
V
E
L
S
T
L
D
G
G
L
R
L
V
E
R
R
R
P
V
G
V
I
G
A
N
Y
E
A
R
-
P
-
N
-
V
T
V
D
V
A
S
Q
L
V
K
S
R
N
A
G
V
L
R
T
G
S
A
A
L
----
K
S
A
Q
R
L
L
E
V
V
I
R
P
A
L
----
T
D
S
G
I
D
A
N
V
V
Q
L
V
P
R
P
E
R
E
A
A
G
A
-
L
V
R
L
P
D
L
V
P
L
V
I
L
R
G
S
G
E
S
T
R
A
L
A
L
---
E
---------
A
A
Q
H
G
V
R
T
L
A
H
A
D
-
G
G
G
V
L
Y
V
D
E
K
A
D
R
D
T
V
R
S
L
V
V
N
S
-
L
D
R
-
L
G
V
C
N
R
L
N
L
L
L
I
H
D
A
V
Y
E
E
-
F
----------------
W
P
V
V
S
E
A
L
A
E
R
G
V
S
P
S
L
P
P
-----------------
Y
-----------------
D
H
--------
P
I
--
G
--------------------
Y
------------------------
E
W
A
----
L
-------
D
S
E
R
E
-------
A
T
V
T
V
A
R
V
D
--
G
V
A
E
A
V
R
I
A
N
E
E
T
S
G
L
A
A
G
I
A
T
E
D
A
R
A
A
E
E
F
F
D
G
Y
Q
G
T
G
V
F
W
N
A
P
T
R
L
L
D
--
G
F
K
L
L
G
V
P
E
T
G
I
N
L
D
K
V
P
G
P
R
G
P
V
T
Y
P
D
L
Y
V
R
Q
Y
A
V
L
-------
72
HHSearch
63.24
40%
12
- C3 -
-
1VLU
-
PROA_YEAST
B:
[13-444]
-----
M
S
S
S
Q
Q
I
A
K
N
A
R
K
A
G
N
--
I
L
K
T
I
S
N
E
G
R
S
D
I
L
Y
K
I
H
D
A
L
K
A
-------
N
A
H
A
I
E
E
A
N
K
I
D
L
A
V
A
K
E
T
G
L
A
D
S
L
L
K
R
L
D
L
F
K
G
D
-
K
F
E
V
-
M
L
Q
G
I
K
D
V
A
E
L
E
-
D
-
P
-
V
-
G
K
V
K
M
A
R
E
L
D
D
G
L
T
L
Y
Q
V
T
A
P
V
G
V
L
L
V
I
F
E
S
R
-
P
-
E
-
V
I
A
N
I
T
A
L
S
I
K
S
G
N
A
A
I
L
K
G
G
K
E
S
V
----
N
T
F
R
E
M
A
K
I
V
-
N
D
T
I
A
Q
F
Q
S
E
T
G
V
P
V
G
S
V
Q
L
I
E
T
----
D
V
S
D
-
L
L
D
Q
D
E
Y
I
D
L
V
V
P
R
G
S
N
A
L
V
R
K
I
K
D
---
T
---------
T
K
---
I
P
V
L
G
H
A
D
-
G
I
C
S
I
Y
L
D
E
D
A
D
L
I
K
A
K
R
I
S
L
D
A
K
T
N
------
N
A
M
E
T
L
L
I
N
P
K
F
-
S
K
-
W
----------------
W
E
V
L
E
N
L
T
L
E
G
G
V
T
I
H
A
T
K
-----------------
D
-----------------
L
K
T
A
Y
F
D
K
L
N
E
L
G
-
K
--------------------
L
T
E
A
---------------------
I
Q
C
K
TVD
A
-------
D
----------
S
L
D
L
A
A
K
F
V
T
--
S
T
E
S
A
I
Q
H
I
N
T
H
S
S
R
H
T
D
A
I
V
T
E
N
K
A
N
A
E
K
F
M
K
G
V
D
S
S
G
V
Y
W
N
A
S
T
R
F
A
D
G-------------------------
G
L
D
G
L
V
S
Y
Q
Y
Q
I
R
G
D
G
Q
V
A
-
68
HHSearch
62.73
18%
-22
- C3 -
-
5KF6
4
?
B:
[609-1042]
--
E
T
S
E
E
D
A
R
R
A
V
R
L
A
A
D
A
A
P
--
D
W
A
A
V
P
P
S
E
R
A
A
C
L
D
R
A
A
E
L
M
Q
A
-------
R
M
P
T
L
L
G
L
I
I
R
E
A
G
K
S
A
----
L
N
A
I
---------
A
-
E
V
R
E
-
A
I
D
F
L
R
Y
Y
A
E
Q
T
-
R
-
R
-
T
---------------
L
G
P
G
H
G
P
L
G
P
I
V
C
I
S
P
W
N
F
P
L
A
-
I
F
T
G
Q
I
A
A
A
L
V
A
G
N
P
V
L
A
K
P
A
E
E
T
P
----
L
I
A
A
E
G
V
R
I
L
-
R
E
A
--------
G
I
P
A
S
A
L
Q
L
L
P
G
-
D
G
R
-
V
G
A
-
A
L
V
A
A
A
E
T
A
G
V
M
F
T
G
S
T
E
V
A
R
L
I
Q
A
---
Q
L
A
D
R
LSPAG
R
P
---
I
P
L
I
A
E
T
G
-
G
Q
N
A
M
I
V
D
S
S
A
L
A
E
Q
V
V
G
D
V
I
T
S
A
F
D
S
A
G
Q
R
C
S
A
L
R
V
L
C
L
Q
E
D
V
A
D
R
-
I
----------------
L
T
M
L
K
G
A
L
H
E
L
H
I
---
G
R
T
-----------------
D
RLSVD
V
G
P
V
IT
S
E
A
K
D
N
I
E
--------
K
H
I
-
E
--------------------
R
M
R
G
L
G
R
K
V
E
Q
I
G
L
A
SETGV
G
T
---
F
V
P
----
P
T
I
I
E
L
--
E
K
L
S
D
L
Q
R
E
V
F
G
P
V
L
H
V
I
R
Y
R
RD
D
L
D
R
L
V
D
D
V
N
A
T
G
Y
G
L
T
F
G
L
H
T
R
L
D
E
T
I
A
H
V
T
S
R
I
K
A
G
N
L
Y
I
N
R
N
I
I
G
A
V
VG
V
Q
P
F
G
G
R
G
L
S
G
T
G
---
P
K
A
-
G
G
P
L
Y
L
G
R
L
V
T
T
A
P
V
P
P
Q
------
69
HHSearch
62.69
18%
-23
- C3 -
-
5KF7
3
?
A:
[609-1042]
--
E
T
S
E
E
D
A
R
R
A
V
R
L
A
A
D
A
A
P
--
D
W
A
A
V
P
P
S
E
R
A
A
C
L
D
R
A
A
E
L
M
Q
A
-------
R
M
P
T
L
L
G
L
I
I
R
E
A
G
K
S
A
----
L
N
A
I
---------
A
-
E
V
R
E
-
A
I
D
F
L
R
Y
Y
A
E
Q
T
-
R
-
R
-
T
---------------
L
G
P
G
H
G
P
L
G
P
I
V
C
I
S
P
W
N
F
P
L
A
-
I
F
T
G
Q
I
A
A
A
L
V
A
G
N
P
V
L
A
K
P
A
E
E
T
P
----
L
I
A
A
E
G
V
R
I
L
-
R
E
A
--------
G
I
P
A
S
A
L
Q
L
L
P
G
-
D
G
R
-
V
G
A
-
A
L
V
A
A
A
E
T
A
G
V
M
F
T
G
S
T
E
V
A
R
L
I
Q
A
---
Q
L
A
D
R
LSPAG
R
P
---
I
P
L
I
A
E
T
G
-
G
Q
N
A
M
I
V
D
S
S
A
L
A
E
Q
V
V
G
D
V
I
T
S
A
F
D
S
A
G
Q
R
C
S
A
L
R
V
L
C
L
Q
E
D
V
A
D
R
-
I
----------------
L
T
M
L
K
G
A
L
H
E
L
H
I
---
G
R
T
-----------------
D
RLSVD
V
G
P
V
IT
S
E
A
K
D
N
I
E
--------
K
H
I
-
E
--------------------
R
M
R
G
L
G
R
K
V
E
Q
I
G
L
A
SETGV
G
T
---
F
V
P
----
P
T
I
I
E
L
--
E
K
L
S
D
L
Q
R
E
V
F
G
P
V
L
H
V
I
R
Y
R
RD
D
L
D
R
L
V
D
D
V
N
A
T
G
Y
G
L
T
F
G
L
H
T
R
L
D
E
T
I
A
H
V
T
S
R
I
K
A
G
N
L
Y
I
N
R
N
I
I
G
A
V
VG
V
Q
P
F
G
G
R
G
L
S
G
T
G
---
P
K
A
-
G
G
P
L
Y
L
G
R
L
V
T
T
A
P
V
P
P
Q
------
70
HHSearch
61.96
21%
-8
- C3 -
-
3PQA
-
LADH_METJA
B:
[29-465]
-
P
A
L
S
R
E
E
A
K
E
A
I
D
T
A
E
K
Y
K
E
--
V
M
K
N
L
P
I
T
K
R
Y
N
I
L
M
N
I
A
K
Q
I
K
E
-------
K
K
E
E
L
A
K
I
L
A
I
D
A
G
K
P
I
----
K
Q
A
R
V
-
E
---------
V
E
R
-
S
I
G
T
F
K
L
A
A
F
Y
V
-
K
E
H
-
R
-
D
E
V
I
P
----
S
D
D
R
L
I
F
T
R
R
E
P
V
G
I
V
G
A
I
T
P
F
N
F
P
L
N
-
L
S
A
H
K
I
A
P
A
I
A
T
G
N
V
I
V
H
H
P
S
S
K
A
P
----
L
V
C
I
E
L
A
K
I
I
-
E
N
A
L
----
K
K
Y
N
V
P
L
G
V
Y
N
L
L
T
G
-
A
G
E
V
V
G
D
-
E
I
V
V
N
E
K
V
N
M
I
S
F
T
G
S
S
K
V
G
E
L
I
T
K
---
K
A--------
G
F
---
K
K
I
A
L
E
L
G
-
G
V
N
P
N
I
V
L
K
D
A
D
L
N
K
A
V
N
A
L
I
K
G
S
F
I
Y
A
G
Q
V
C
I
S
V
G
M
I
L
V
D
E
S
I
A
D
K
-
F
----------------
I
E
M
F
V
N
K
A
K
V
L
N
V
---
G
N
P
-----------------
L
DEKTD
V
G
P
L
IS
V
E
H
A
E
W
V
E
--------
K
V
V
-
E
--------------------
K
A
I
D
E
GGKLLLGGKRDKA-------
L
F
Y
----
P
T
I
L
E
V
D
-
R
D
N
I
L
C
K
T
E
T
F
A
P
V
I
P
I
I
R
T
---
N
E
E
E
M
I
D
I
A
N
S
T
E
Y
G
L
H
S
A
I
F
T
N
D
I
N
K
S
L
K
F
A
E
N
L
E
F
G
G
V
V
I
N
D
S
S
L
F
R
Q
D-
N
M
P
F
G
G
V
K
K
S
G
L
G
----
R
E
-
G
V
K
Y
A
M
E
E
M
S
N
I
K
T
I
I
I
S
K
A
----
71
HHSearch
61.81
18%
25
- C3 -
-
4QF6
-
?
F:
[52-492]
-
C
E
A
Q
E
E
D
I
D
A
A
V
K
A
A
R
S
A
F
E
SG
P
W
A
E
M
T
T
A
E
R
A
H
L
I
Y
K
L
A
D
L
I
E
E
-------
H
R
E
E
L
A
Q
L
E
A
L
D
N
G
K
P
Y
----
Q
V
A
L
D
D
D
---------
I
S
A
-
T
V
E
N
Y
R
Y
Y
A
G
W
T
-
T
-
K
I
I
-
G
Q
T
I
P
I
---
S
K
D
Y
L
N
Y
T
R
H
E
P
V
G
V
V
G
Q
I
I
P
W
N
F
P
L
V
-
M
S
S
W
K
M
G
A
A
L
A
T
G
C
T
I
V
L
K
P
A
S
Q
T
P
----
L
S
L
L
Y
A
A
K
L
F
-
K
E
A
--------
G
F
P
N
G
V
V
N
F
V
P
G
-
F
G
P
E
A
G
A
-
A
I
V
N
H
H
D
I
D
K
V
A
F
T
G
S
T
V
T
G
K
Y
I
M
R
---
Q
SAE------
M
I
---
K
H
V
T
L
E
L
G
-
G
K
S
P
N
I
I
L
E
D
A
D
L
E
E
A
I
N
G
A
F
Q
G
I
M
Y
N
H
G
Q
N
C
S
A
G
S
R
V
F
V
H
R
K
H
Y
E
T
-
V
----------------
V
D
A
L
V
K
M
A
N
N
V
K
L
---
G
A
G
MEKETEMGPLVSKKQQE
R
-----------------
V
L
--------
N
Y
I
-
E
--------------------
Q
GKKEGATVAAGGERALEKGY----
F
V
K
----
P
TVFTDVT
D
D
M
T
I
V
K
E
E
I
F
G
P
V
V
V
V
L
P
F
D
--
S
T
E
E
V
I
E
R
A
N
N
S
S
Y
G
L
A
A
G
V
W
T
Q
N
I
K
T
G
H
Q
V
A
N
K
L
K
A
G
T
V
W
I
N
D
Y
N
L
E
N
A
--
A
A
P
F
G
G
Y
K
Q
S
G
I
G
----
R
E
-
L
G
S
Y
A
L
D
N
Y
T
E
V
K
S
V
W
V
N
------
62
HHSearch
61.16
18%
-8
- C3 -
-
3HAZ
3
?
A:
[545-987]
-
A
D
A
T
P
D
Q
A
H
A
A
V
A
A
A
R
A
G
F
A
--
G
W
S
R
T
P
A
G
I
R
A
A
A
L
E
Q
A
A
H
L
L
E
S
-------
R
S
A
H
F
I
A
L
L
Q
R
E
G
G
K
T
L
----
D
D
A
L
---------
S
-
E
L
R
E
-
A
A
D
F
C
R
Y
Y
A
A
Q
G
-
R
-
K
L
F
-
G
S
E
T
A
M
-
P
G
P
T
G
E
S
N
A
L
T
M
R
G
R
G
V
F
V
A
I
S
P
W
N
F
P
L
A
-
I
F
L
G
Q
V
T
A
A
L
M
A
G
N
S
V
V
A
K
P
A
E
Q
T
P
----
R
I
A
R
E
A
V
A
L
L
-
H
E
A
--------
G
I
P
K
S
A
L
Y
L
V
T
G
-
D
G
R
-
I
G
A
-
A
L
T
A
H
P
D
I
A
G
V
V
F
T
G
S
T
E
V
A
R
S
I
N
R
---
A
L
A
A
KDG---
P
I
---
V
P
L
I
A
E
T
G
-
G
I
N
A
M
I
A
D
A
T
A
L
P
E
Q
V
A
D
D
V
V
T
S
A
F
R
S
A
G
Q
R
C
S
A
L
R
L
L
F
V
Q
E
D
V
A
D
R
-
M
----------------
I
E
M
V
A
G
A
A
R
E
L
K
I
---
G
D
P
-----------------
S
DVATH
V
G
P
V
ID
V
E
A
K
Q
R
L
D
--------
A
H
I
-
A
--------------------
R
M
K
T
E
ARLH
F
A
G
P
A
P
EGC-------
F
V
A
----
P
H
I
F
E
L
--
T
E
A
G
Q
L
T
E
E
V
F
G
P
I
L
H
V
V
R
Y
R
PE
N
L
E
R
V
L
R
A
I
E
R
T
G
Y
G
L
T
L
G
V
H
S
R
I
D
D
S
I
E
A
I
I
D
R
V
Q
V
G
N
I
Y
V
N
R
N
M
I
G
A
V
VG
V
Q
P
F
G
G
N
G
L
S
G
T
G
---
P
K
A
-
G
G
P
H
Y
L
A
R
F
A
T
E
Q
T
V
T
I
N
T
-----
1
PsiBlast_PDB
60.82
62%
-
- C- -
-
4GHK
-
PROA_BURTA
A:
[3-423]
----
I
D
Q
Y
M
T
D
V
G
R
R
A
R
R
A
S
R
--
S
I
A
R
A
S
T
A
A
K
N
A
A
L
E
A
V
A
R
A
I
E
R
-------
D
A
G
A
L
K
A
A
N
A
R
D
V
A
R
------
D
A
A
F
V
D
R
L
T
L
S
-
D
K
-
A
L
K
T
-
M
V
E
G
L
R
Q
V
A
T
L
P
-
D
-
P
-
I
-
G
E
M
S
N
L
K
Y
R
P
S
G
I
Q
V
G
Q
M
R
V
P
L
G
V
I
G
I
I
Y
E
S
R
-
P
-
N
-
V
T
I
D
A
A
A
L
C
L
K
S
G
N
A
T
I
L
R
G
G
S
E
A
L
----
E
S
N
T
A
L
A
K
L
I
-
G
E
G
L
----
A
E
A
G
L
P
Q
D
T
V
Q
V
V
E
T
A
D
R
A
A
V
G
R
-
L
I
T
M
T
E
Y
V
D
V
I
V
P
R
G
G
K
S
L
I
E
R
L
I
N
---
E
---------
A
R
---
V
P
M
I
K
H
L
D
-
G
I
C
H
V
Y
V
D
D
R
A
S
V
T
K
A
L
T
V
C
D
----------
C
N
T
M
E
T
L
L
V
A
R
G
I
A
P
A
-
V
----------------
L
S
P
L
G
R
L
Y
R
E
K
G
V
E
L
R
V
D
A
-----------------
D
-----------------
A
R
--------
A
V
L
E
A
--------------------
A
------------------------
G
V
G
----
P
LVD----
A
T
D
E
D
W
R
T
E
---
P
V
L
A
I
K
I
V
D
--
G
I
D
A
A
I
E
H
I
N
E
Y
G
S
H
H
T
D
A
I
V
T
E
D
H
D
R
A
M
R
F
L
R
E
V
D
S
A
S
V
M
V
N
A
S
T
R
F
A
D
--
G
F
E
F
G
L
G
A
E
I
G
I
S
N
D
K
L
H
A
-
R
G
P
V
G
L
E
G
L
T
S
L
K
Y
V
V
L
G
H
G
E
G
R
Q
61
HHSearch
60.76
18%
-7
- C3 -
-
3HAZ
2
?
B:
[545-987]
-
A
D
A
T
P
D
Q
A
H
A
A
V
A
A
A
R
A
G
F
A
--
G
W
S
R
T
P
A
G
I
R
A
A
A
L
E
Q
A
A
H
L
L
E
S
-------
R
S
A
H
F
I
A
L
L
Q
R
E
G
G
K
T
L
----
D
D
A
L
---------
S
-
E
L
R
E
-
A
A
D
F
C
R
Y
Y
A
A
Q
G
-
R
-
K
L
F
-
G
S
E
T
A
M
-
P
G
P
T
G
E
S
N
A
L
T
M
R
G
R
G
V
F
V
A
I
S
P
W
N
F
P
L
A
-
I
F
L
G
Q
V
T
A
A
L
M
A
G
N
S
V
V
A
K
P
A
E
Q
T
P
----
R
I
A
R
E
A
V
A
L
L
-
H
E
A
--------
G
I
P
K
S
A
L
Y
L
V
T
G
-
D
G
R
-
I
G
A
-
A
L
T
A
H
P
D
I
A
G
V
V
F
T
G
S
T
E
V
A
R
S
I
N
R
---
A
L
A
A
KDG---
P
I
---
V
P
L
I
A
E
T
G
-
G
I
N
A
M
I
A
D
A
T
A
L
P
E
Q
V
A
D
D
V
V
T
S
A
F
R
S
A
G
Q
R
C
S
A
L
R
L
L
F
V
Q
E
D
V
A
D
R
-
M
----------------
I
E
M
V
A
G
A
A
R
E
L
K
I
---
G
D
P
-----------------
S
DVATH
V
G
P
V
ID
V
E
A
K
Q
R
L
D
--------
A
H
I
-
A
--------------------
R
M
K
T
E
ARLHFAGPAPEGC-------
F
V
A
----
P
H
I
F
E
L
--
T
E
A
G
Q
L
T
E
E
V
F
G
P
I
L
H
V
V
R
Y
R
PE
N
L
E
R
V
L
R
A
I
E
R
T
G
Y
G
L
T
L
G
V
H
S
R
I
D
D
S
I
E
A
I
I
D
R
V
Q
V
G
N
I
Y
V
N
R
N
M
I
G
A
V
VG
V
Q
P
F
G
G
N
G
L
S
G
T
G
---
P
K
A
-
G
G
P
H
Y
L
A
R
F
A
T
E
Q
T
V
T
I
N
T
-----
65
HHSearch
60.06
17%
37
- C3 -
-
4QTO
2
?
D:
[65-512]
-
S
E
G
T
K
E
D
A
E
R
A
I
L
A
A
R
R
A
F
E
SG
E
W
S
Q
E
T
A
E
T
R
G
K
K
V
R
A
I
A
D
K
I
K
E
-------
H
R
E
A
L
A
R
L
E
T
L
D
T
G
K
T
L
----
E
E
S
Y
A
----------
D
M
D
D
-
I
H
N
V
F
M
Y
F
A
G
L
A
-
D
-
K
D
G
-
G
E
M
I
D
S
--
P
I
P
D
T
E
S
K
I
V
K
E
P
V
G
V
V
T
Q
I
T
P
W
N
Y
P
-
L
L
Q
A
S
W
K
I
A
P
A
L
A
T
G
C
S
L
V
M
K
P
S
E
I
T
P
----
L
T
T
I
R
V
F
E
L
M
-
E
E
V
--------
G
F
P
K
G
T
I
N
L
I
L
G
-
A
G
S
E
V
G
D
-
V
M
S
G
H
K
E
V
D
L
V
S
F
T
G
G
I
E
T
G
K
H
I
M
K
NAA
N
---------
N
V
---
T
N
I
A
L
E
L
G
-
G
K
N
P
N
I
I
F
D
D
A
D
F
E
L
A
V
D
Q
A
L
N
G
G
Y
F
H
A
G
Q
V
C
S
A
G
S
R
I
L
V
Q
N
S
I
K
D
K
-
F
----------------
E
Q
A
L
I
D
R
V
K
K
I
K
L
---
G
N
G
-----------------
F
DADTEMGPVISTEHRNK
I
E
--------
S
Y
M
-
D
--------------------
V
AKAEGATIAVGGKRPDRDDLKDGL
F
F
E
----
P
TVITNCD
T
S
M
R
I
V
Q
E
E
V
F
G
P
V
V
T
V
E
G
F
E
--
T
E
Q
E
A
I
Q
L
A
N
D
S
I
Y
G
L
A
G
A
V
F
S
K
D
I
G
K
A
Q
R
V
A
N
K
L
K
L
G
T
V
W
I
N
D
F
H
P
Y
F
A
--
Q
A
P
W
G
G
Y
K
Q
S
G
I
G
R
----
E
-
L
G
K
E
G
L
E
E
Y
L
V
S
K
H
I
L
T
N
T
N
P
---
60
HHSearch
59.97
18%
13
- C3 -
-
3R31
1
BETB_AGRFC
B:
[47-489]
-
H
A
A
T
P
A
I
V
E
R
A
I
A
S
A
K
R
A
Q
K
--
E
W
A
A
M
S
P
M
A
R
G
R
I
L
K
R
A
A
D
I
M
R
E
-------
R
N
D
A
L
S
T
L
E
T
L
D
T
G
K
P
I
----
Q
E
T
I
V
A
D
P
T
S
G
-
A
D
-
A
F
E
F
-
F
G
G
I
A
P
S
A
-------
L
-
N
-
G
D
Y
I
P
L
----
G
G
D
F
A
Y
T
K
R
V
P
L
G
V
C
V
G
I
G
A
W
N
Y
P
Q
Q
-
I
A
C
W
K
A
A
P
A
L
V
A
G
N
A
M
V
F
K
P
S
E
N
T
P
----
L
G
A
L
K
I
A
E
I
L
-
I
E
A
--------
G
L
P
K
G
L
F
N
V
I
Q
G
-
D
R
-
D
T
G
P
-
L
L
V
N
H
P
D
V
A
K
V
S
L
T
G
S
V
P
T
G
R
K
V
A
A
AAA
G
---------
H
L
---
K
H
V
T
M
E
L
G
-
G
K
S
P
M
I
V
F
D
D
A
D
I
E
S
A
V
G
G
A
M
L
G
N
F
Y
S
S
G
Q
V
C
S
N
G
T
R
V
F
V
Q
K
K
A
K
A
R
-
F
----------------
L
E
N
L
K
R
R
T
E
A
M
I
L
---
G
D
P
LDYATHLGPLVSKAQQE
K
-----------------
V
L
--------
S
Y
I
-
E
--------------------
K
GKAEGATLITGGGIPNNVAGEGA-
Y
V
Q
----
P
TVFADVT
D
D
M
T
I
A
R
E
E
I
F
G
P
V
M
C
V
L
D
F
D
--
D
E
D
E
V
L
A
R
A
N
A
T
E
F
G
L
A
G
G
V
F
T
A
D
L
A
R
A
H
R
V
V
D
G
L
E
A
G
T
L
W
I
N
T
Y
N
L
C
P
V
--
E
I
P
F
G
G
S
K
Q
S
G
F
G
R
----
E
-
N
S
A
A
A
L
E
H
Y
S
E
L
K
T
V
Y
V
S
T
G
----
3
PsiBlast_PDB
59.72
40%
7
- C3 -
-
1VLU
-
PROA_YEAST
A:
[17-443]
---------
Q
Q
I
A
K
N
A
R
K
A
G
N
--
I
L
K
T
I
S
N
E
G
R
S
D
I
L
Y
K
I
H
D
A
L
K
A
-------
N
A
H
A
I
E
E
A
N
K
I
D
L
A
V
A
K
E
T
G
L
A
D
S
L
L
K
R
L
D
L
F
-
K
G
D
K
F
E
V
-
M
L
Q
G
I
K
D
V
A
E
L
E
-
D
-
P
-
V
-
G
K
V
K
M
A
R
E
L
D
D
G
L
T
L
Y
Q
V
T
A
P
V
G
V
L
L
V
I
F
E
S
R
-
P
-
E
-
V
I
A
N
I
T
A
L
S
I
K
S
G
N
A
A
I
L
K
G
G
K
E
S
V
N
T
F
R
E
M
A
K
I
V
N
D
T
I
-
A
Q
F
Q
----
S
E
T
G
V
P
V
G
S
V
Q
L
I
E
T
--
R
--
V
S
D
-
L
L
D
Q
D
E
Y
I
D
L
V
V
P
R
G
S
N
A
L
V
R
K
I
K
D
---
T
---------
T
K
---
I
P
V
L
G
H
A
D
-
G
I
C
S
I
Y
L
D
E
D
A
D
L
I
K
A
K
R
I
S
L
D
A
K
T
N
-----
C
N
A
M
E
T
L
L
I
N
P
K
F
S
K
W
-
W
E
V
L
E
N
L
T
LEGGVTIHA
T
K
D
L
K
T
A
Y
F
D
K
L
N
E
L
G
K
L
T
-----------------
E
-----------------
A
----------
I
Q
-
C
--------------------
K
------------------------
T
V
------------------------
S
L
D
L
A
A
K
F
V
T
--
S
T
E
S
A
I
Q
H
I
N
T
H
S
S
R
H
T
D
A
I
V
T
E
N
K
A
N
A
E
K
F
M
K
G
V
D
S
S
G
V
Y
W
N
A
S
T
R
F
A
D
-------------------------
V
G
L
D
G
L
V
S
Y
Q
Y
Q
I
R
G
D
G
Q
V
--
58
HHSearch
59.21
19%
14
- C3 -
-
4PXL
10
?
A:
[69-516]
-
A
E
G
D
K
A
D
V
D
L
A
V
K
A
A
R
E
A
F
D
NG
P
W
P
R
M
T
G
Y
E
R
G
R
I
L
H
R
F
A
D
L
I
D
E
-------
H
V
E
E
L
A
A
L
D
T
V
D
A
G
K
L
F
----
A
V
G
K
A
R
D
---------
I
P
G
-
A
A
H
L
L
R
Y
Y
A
G
A
A
-
D
-
K
-
V
H
G
A
T
L
K
M
---
A
Q
R
M
H
G
Y
T
L
K
E
P
V
G
V
V
G
H
I
V
P
W
N
Y
P
-
T
T
M
F
F
F
K
V
G
P
A
L
A
A
G
C
A
V
V
V
K
P
A
E
Q
T
P
----
L
S
A
L
F
Y
A
H
L
A
-
R
E
A
--------
G
V
P
A
G
V
L
N
V
V
P
G
-
F
G
P
T
A
G
A
-
A
V
A
A
H
M
D
V
D
K
V
S
F
T
G
S
T
E
V
G
R
L
V
M
R
---
A
A
A
E
S
-----
N
L
---
K
P
V
S
L
E
L
G
-
G
K
S
P
V
I
V
F
D
D
A
D
L
D
M
A
V
N
L
V
N
F
A
T
Y
T
N
K
G
E
I
C
V
A
G
T
R
I
Y
V
Q
E
G
I
Y
D
E
-
F
----------------
V
K
K
A
A
E
L
A
S
K
S
V
V
---
G
D
P
-----------------
F
NPSVSQGPQV
D
K
D
Q
Y
E
K
V
L
--------
R
Y
I
-
D
--------------------
I
G
K
R
E
G
A
T
LVTG
G
K
P
C
GDKGY----
Y
I
E
----
P
T
I
F
TDVK
D
D
M
T
I
A
Q
D
E
I
F
G
P
V
M
A
L
M
K
F
K
--
T
V
E
E
V
I
Q
K
A
N
N
T
R
Y
G
L
A
A
G
I
V
T
K
N
I
D
V
A
N
T
V
S
R
S
I
R
A
G
A
I
W
I
N
C
Y
F
A
F
D
P
--
D
A
P
F
G
G
Y
K
M
S
G
F
G
K
----
D
-
M
G
M
D
A
L
D
K
Y
L
Q
T
K
T
V
V
T
P
L
Y
N
T
P
W
57
HHSearch
58.36
16%
2
- C3 -
-
5X5T
1
KGSDH_AZOBR
A:
[65-503]
-
A
H
A
G
I
A
D
L
D
R
A
L
A
A
A
Q
S
G
F
E
--
A
W
R
K
V
P
A
H
E
R
A
A
T
M
R
K
A
A
A
L
V
R
E
-------
R
A
D
A
I
A
Q
L
M
T
Q
E
Q
G
K
P
L
----
T
E
A
R
V
-
E
---------
V
L
S
-
A
A
D
I
I
E
W
F
A
D
E
G
-
R
R
V
-
Y
-
G
R
I
V
P
P
-
R
-
N
L
G
A
Q
Q
T
V
V
K
E
P
V
G
P
V
A
A
F
T
P
W
N
F
P
V
N
-
Q
V
V
R
K
L
S
A
A
L
A
T
G
C
S
F
L
V
K
A
P
E
E
T
P
----
A
S
P
A
A
L
L
R
A
F
-
V
D
A
--------
G
V
P
A
G
V
I
G
L
V
Y
G
-
D
P
A
E
I
S
S
-
Y
L
I
P
H
P
V
I
R
K
V
T
F
T
G
S
T
P
V
G
K
Q
L
A
S
---
L
A
G
L
------
H
M
---
K
R
A
T
M
E
L
G
-
G
H
A
P
V
I
V
A
E
D
A
D
V
A
L
A
V
K
A
A
G
G
A
K
F
R
N
A
G
Q
V
C
I
S
P
T
R
F
L
V
H
N
S
I
R
D
E
-
F
----------------
T
R
A
L
V
K
H
A
E
G
L
K
V
---
G
N
G
-----------------
L
EEGTTLGALAN
P
R
R
L
T
A
M
A
--------
S
V
I
-
D
N
A
R
K
V
GASIETGGERIGSEG
N
------------------------
F
F
A
----
P
T
V
I
A
NVP
L
D
A
D
V
F
N
N
E
P
F
G
P
V
A
A
I
R
G
F
D
--
K
L
E
E
A
I
A
E
A
N
R
L
P
F
G
L
A
G
Y
A
F
T
R
S
F
A
N
V
H
L
L
T
Q
R
L
E
V
G
M
L
W
I
N
Q
P
A
T
P
W
P
--
E
M
P
F
G
G
V
K
D
S
G
Y
G
S
----
E
-
G
G
P
E
A
L
E
P
Y
L
V
T
K
S
V
T
V
M
------