@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKT8: (2017-10-29 )
MDLPNPVLAKVTERVIARSQKTRSAYLQRIEHAQGKFPARGALSCANLAHGFAGMEDNEKLIIKVGREPNIGIVSSYNEMLSAHAPYKTFPDIIKTAARENGGVAQFAGGVPAMCDGITQGNASMELSLFSRETIAMGTAIALSHNMFDAALCLGVCDKIVPGLLIGALQFGYLPTIFVPAGPMSSGLSNDDKAKIRQQFATGQVGRDALLEAESAAYHGQGTCTFYGTANSNQMLMEVMGLHLPSAAFVHPHTPLRDALTAEAAKRVLDLTAEQGNYTPIGHVIDEKAIINGIVALLATGGSTNHTLHLIAIAHAAGILIDWDDFDELSAVVPLLAKIYPNGKADVNHFQAAGGVAFLIRNLLEAGLLHNDVKTVAGKGLQHYTKEPKLIDGKLTWVDGVVQSLDDKVLRSIDAPFQPDGGLRLMQGRLGRGVIKISAVAPEHRKVKAPAIVFDSQEAVQAAFDRGELHRDFIAVVRFQGARANGMPELHRLTPVLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLNGPIGKVQTGDMLIIDAEAGVLDIELDEQTWQSRPVAQPEHQAENEVGFGRELFGVFRAAAAPAEHGASVFGALVGEEPQGQI
Atome Classification :
(20 SA)
--------------------....----.....10.........-20-..--......30..--......40........--50..----------......60......-..70.......--.80........90........100..-...-..110.......120...-....130-----.......-..140.--.---------.....150-.........160--------------....---------------------------------...--..170.......180.......190.-------.-------...-..200..-------......-210.......220........-230..-.....240------.......250...--..--..260.......270......------.---280...---.--...290---..-......300.......--310.......320------.........330..--.....340........-350...--....360--..----.....370...-----....380........390----------......-----.----.400......-----.410.......420.......430-.--....------...440.......450------.....-..460---....--..--.--..470.-......480..-.-....490---......-.500......--.-510--------------.--..--------------..-.-----.520.......530......----.540----..-......550.------...-----------------------...-560-....-----------....570.......580.......590.......600.......610.....--------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------MDLP----
N
P
V
L
A
K
-
V
T
E
R
V
I
A
RS-
Q
K
-
T
R
--
S
A
Y
L
Q
R
I
E
HA--QGKFPARG
A
L
S
C
A
N
L
A
--
H
GFA----------GMEDN
E
K
L
I
I
K
VGR-EPNI
G
I
V
S
S
Y
N
--
E
M
L
SAHAPYKT
F
P
D
I
I
K
T
A
A
RENGGV-
A
Q
F-AGGV
P
A
M
CDGITQGNA
S
M
-
E
L
S
L
F
-------SRETIAM-
G
T
A
I
A
L--S---------HN
M
F
D
A
---
A
L
C
L
G
V
C
D
K
I
----------------
V
P
G
L
---------------------------------
L
I
G
--
A
L
Q
FGYL
P
T
I
F
VPAGPMSSGLSN
D
D
K
-------
A
-------
K
I
R
-
Q
Q
F-ATG-------QV
G
R
D
A
-
L
LEAESAAYHG-
Q
G
T
C
T
F
Y
GT-ANS
N
Q
-
M
L
M
E
V
M
GL------HLPSAAFVHPHT
P
--
L
R
--
D
A
L
T
A
E
A
A
K
R
V
L
D
LTAEQGNY------T---P
I
G
H
VI---
D
--
E
K
A
I
I
----
N
G
-
I
V
A
L
L
ATGGST
N
H
T
L
H
--
L
I
A
I
AHA
A
G
I
L
--------
I
DWD
D
F
D
E
L
S
A
V
V
P
--
L
L
A
K
IY-PNGKAD
V
N
H
-
F
QAAG
G
--
V
A
F
L
I
R
N
--
L
L
----
E
A
G
L
L
H
N
D
V
K
T
-----
V
A
G
K
G
L
-
Q
H
YTKEPKLI-----------DG
K
L
T
W
-----
V
----
D
G
V
V
Q
S
L
D
D
K
-----
V
L
R
S
IDAPFQPDGGL
R
L
M
Q
GRLG--R--
G
V
I
K
------
I
S
AVAPEHRKVKA
P
A
I
------
V
FD
S
Q
-
E
A
V
-----
Q
A
A
F
--
D
R
--
G
--
E
L
H
R
D
F
-
I
A
V
V
RFQGARA-N-GM
P
E
L
H
R
---
L
T
P
V
L
G
-
V
LQDQ
G
F
H
V
A
--
L
-
V
TD--------------G--RM--------------SG-A-----SGKV
P
A
V
I
HL
S
P
E
A
LLNGPI----GKV-----QT-G
D
M
L
I
I
DAEA------
G
V
L
-----------------------
D
I
E-L-D-
E
Q
T
W-----------QSRPVAQPEHQAENEVG
F
G
R
E
L
F
G
V
F
R
A
AAAPAE
H
G
A
S
V
F
G
A
L
VGEEPQGQI--------------------------------------------------------------------------------------------------------------------
28
HHSearch
80.40
59%
-21
- C6 -
-
2GP4
-
?
A:
[0-604]
----------------------
H
M
----
H
S
V
V
Q
S
-
V
T
D
R
I
I
A
R
S
-
K
A
-
S
R
--
E
A
Y
L
A
A
L
N
D
A
--
R
N
H
-----------------------------------------------------------------------
L
L
K
---
Q
E
V
G
S
V
--
A
Q
V
A
G
-
V
P
--
C
D
G
V
T
Q
G
Q
P
G
M
-
E
L
S
L
L
-------
S
R
E
V
I
A
M
-
A
T
A
V
G
L
--
S
---------
H
N
M
F
D
G
---
A
L
L
L
G
I
C
D
K
I
----------------
V
P
G
L
---------------------------------
L
I
G
--
A
L
S
F
G
H
L
P
M
L
F
V
P
A
G
P
-----------------------------------
G
-------
K
V
D
R
A
Q
-
L
L
E
A
E
A
Q
S
Y
H
S
-
A
G
T
C
T
F
Y
G
------
Q
-
L
M
L
E
V
M
G
L
------
Q
L
P
G
S
S
F
V
N
P
D
D
P
--
L
R
--
E
A
L
N
K
M
A
A
K
Q
V
C
R
L
T
E
---
L
G
------
T
Q
Y
S
P
I
G
E
V
V
---
N
--
E
K
S
I
V
----
N
G
-
I
V
A
L
L
A
T
G
G
S
T
N
L
T
M
H
--
I
V
A
A
A
R
A
A
G
I
I
--------
V
N
W
D
D
F
S
E
L
S
D
A
V
P
--
L
L
A
R
V
Y
-
P
N
G
H
A
D
I
N
H
-
F
H
A
A
G
G
--
M
A
F
L
I
K
E
--
L
L
----
D
A
G
L
L
H
E
D
V
N
T
-----
V
A
G
Y
G
L
R
R
Y
T
Q
E
P
K
L
-
L
-----------
D
G
E
L
R
W
-----
V
----
D
G
P
T
V
S
L
D
T
E
-----
V
L
T
S
V
A
T
P
F
Q
N
N
G
G
L
K
L
L
K
G
N
L
G
--
R
--
A
V
I
K
------
V
S
A
V
Q
P
Q
H
R
V
V
E
A
P
A
V
------
V
I
D
D
Q
-
N
K
L
-----
D
A
L
F
--
K
S
--
G
--
A
L
D
R
D
C
-
V
V
V
V
K
G
Q
G
P
K
A
-
N
-
G
M
P
E
L
H
K
---
L
T
P
L
L
G
-
S
L
Q
D
K
G
F
K
V
A
--
L
-
M
T
D
--------------
G
--
R
M
--------------
S
G
-
A
-----
S
G
K
V
P
A
A
I
H
L
T
P
E
A
I
D
G
G
L
I
----
A
K
V
-----
Q
D
-
G
D
L
I
R
V
D
A
L
T
------
G
E
L
-----------------------
S
L
L
-
V
-
S
-
D
T
E
L
-----------
A
T
R
T
A
T
E
I
D
L
R
-
H
S
R
Y
G
M
G
R
E
L
F
G
V
L
R
S
N
L
S
S
P
E
T
G
A
R
S
T
S
A
I
-----------------------------------------------------------------------------------------------------------------------------
27
HHSearch
79.57
59%
-24
* C6 *
-
2GP4
-
?
B:
[0-604]
----------------------
H
M
----
H
S
V
V
Q
S
-
V
T
D
R
I
I
A
R
S
-
K
A
-
S
R
--
E
A
Y
L
A
A
L
N
D
A
--
R
N
H
--------------------------------------------------------------------------
K
A
C
Q
E
V
G
S
V
--
A
Q
V
A
--
V
P
--
C
D
G
V
T
Q
G
Q
P
G
M
-
E
L
S
L
L
-------
S
R
E
V
I
A
M
-
A
T
A
V
G
L
--
S
---------
H
N
M
F
D
G
---
A
L
L
L
G
I
C
-
K
I
----------------
V
P
G
L
---------------------------------
L
I
G
--
A
L
S
F
G
H
L
P
M
L
F
V
P
A
G
P
----------------------------------------------------------------------------
Q
-
L
M
L
E
V
M
G
L
------
Q
L
P
G
S
S
F
V
N
P
D
D
P
--
L
R
--
E
A
L
N
K
M
A
A
K
Q
V
C
R
L
T
E
---
L
G
------
T
QYS
P
I
G
E
V
V
---
N
--
E
K
S
I
V
----
N
G
-
I
V
A
L
L
A
T
G
G
S
T
N
L
T
M
H
--
I
V
A
A
A
R
A
A
G
I
I
--------
V
N
W
D
D
F
S
E
L
S
D
A
V
P
--
L
L
A
R
V
Y
-
P
N
G
H
A
D
I
N
H
-
F
H
A
A
G
G
--
M
A
F
L
I
K
E
--
L
L
----
D
A
G
L
L
H
E
D
V
N
T
-----
V
A
G
Y
G
L
R
R
Y
T
Q
E
P
K
L
-
L
-----------
D
G
E
L
R
W
-----
V
----
D
G
P
T
V
S
L
D
T
E
-----
V
L
T
S
V
A
T
P
F
Q
N
N
G
G
L
K
L
L
K
G
N
L
G
--
R
--
A
V
I
K
------
V
S
A
V
Q
P
Q
H
R
V
V
E
A
P
A
V
------
V
I
D
D
Q
-
N
K
L
-----
D
A
L
F
--
K
S
--
G
--
A
L
D
R
D
C
-
V
V
V
V
K
G
Q
G
P
K
A
-
N
-
G
M
P
E
L
H
K
---
L
T
P
L
L
G
-
S
L
Q
D
K
G
F
K
V
A
--
L
-
M
T
D
--------------
G
--
R
M
--------------
S
G
-
A
-----
S
G
K
V
P
A
A
I
H
L
T
P
E
A
I
D
G
G
L
I
----
A
K
V
-----
Q
D
-
G
D
L
I
R
V
D
A
L
T
------
G
E
L
-----------------------
S
L
L
-
V
-
S
-
D
T
E
L
-----------
A
T
R
T
A
T
E
I
D
L
R
-
H
S
R
Y
G
M
G
R
E
L
F
G
V
L
R
S
N
L
S
S
P
E
T
G
A
R
S
T
S
A
I
-----------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
64.90
27%
-31
- C6 -
-
5J84
1
?
A:
[54-548]
----------------------------------------------------------------------------------------------------------------
P
V
I
G
I
L
N
T
W
S
--
D
M
T
P
C
N
G
H
L
R
E
L
A
E
K
V
K
A
G
V
W
E
A
G
G
----
F
-
P
L
E
V
P
V
F
S
---
A
S
E
N
T
F
R
-
P
T
A
M
M
-------
Y
R
N
L
A
A
L
-
A
V
E
E
A
I
--
R
---------
G
Q
P
M
D
G
---
C
V
L
L
V
G
C
D
-
T
----------------
T
P
S
L
---------------------------------
L
M
G
--
A
A
S
C
D
-
L
P
S
I
V
V
T
G
G
P
M
L
N
G
Y
F
R
G
E
R
-------
V
G
S
G
T
H
L
W
K
F
S
-
E
M
V
-
K
A
G
-------
E
M
T
Q
A
E
-
F
L
E
A
E
A
S
M
S
R
S
-
S
G
T
C
N
T
M
G
T
-
A
S
T
M
A
-
S
M
A
E
A
L
G
M
------
A
L
S
G
N
A
A
I
P
G
V
D
S
--
R
R
--
K
V
M
A
Q
L
T
G
R
R
I
V
Q
M
V
K
D
--
D
L
------
K
---
P
-
S
E
I
M
---
T
--
K
Q
A
F
E
----
N
A
-
I
R
T
N
A
A
I
G
G
S
T
N
A
V
I
H
--
L
L
A
I
A
G
R
V
G
I
D
--------
L
S
L
D
D
W
D
R
C
G
R
D
V
P
--
T
I
V
N
L
M
-
P
S
G
K
Y
L
M
E
E
-
F
F
Y
A
G
G
--
L
P
V
V
L
K
R
--
L
G
----
E
A
G
L
L
H
K
D
A
L
T
-----
V
S
G
E
T
V
-
W
D
E
V
K
D
----------------------------------
V
V
N
W
N
E
D
-----
V
I
L
P
A
E
K
A
L
T
S
S
G
G
I
V
V
L
R
G
N
L
A
--
P
K
G
A
V
L
K
------
P
S
A
A
S
P
H
L
L
V
H
K
G
R
A
V
------
V
F
E
D
I
-
D
D
Y
-----
K
A
K
I
ND
D
N
--
L
--
D
I
D
E
N
C
-
I
M
V
M
K
N
C
G
P
K
G
-
Y
P
G
M
A
E
V
G
N
---
M
G
L
P
P
K
-
V
L
K
K
G
I
L
D
M
V
--
R
-
I
S
D
--------------
A
--
R
M
--------------
S
G
T
A
-----
Y
G
T
V
--
V
L
H
T
S
P
E
A
A
V
G
G
P
L
----
A
V
V
-----
K
N
-
G
D
M
I
E
L
D
V
P
N
------
R
R
L
-----------------------
H
L
D
-
I
S
D
-
E
E
L
A
-----------
R
R
L
A
E
W
Q
P
N
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.89
27%
-30
- C6 -
-
5J85
1
?
A:
[54-548]
----------------------------------------------------------------------------------------------------------------
P
V
I
G
I
L
N
T
W
S
--
D
M
T
P
C
N
G
H
L
R
E
L
A
E
K
V
K
A
G
V
W
E
A
G
G
----
F
-
P
L
E
V
P
V
F
S
---
A
S
E
N
T
F
R
-
P
T
A
M
M
-------
Y
R
N
L
A
A
L
-
A
V
E
E
A
I
--
R
---------
G
Q
P
M
D
G
---
C
V
L
L
V
G
C
D
-
T
----------------
T
P
S
L
---------------------------------
L
M
G
--
A
A
S
C
D
-
L
P
S
I
V
V
T
G
G
P
M
L
N
G
Y
F
R
G
E
R
-------
V
G
SGTH
L
W
K
F
S
-
E
M
V
-
K
A
G
-------
E
M
T
Q
A
E
-
F
L
E
A
E
A
S
M
S
R
S
-
S
G
T
C
N
T
M
G
T
-
A
S
T
M
A
-
S
M
A
E
A
L
G
M
------
A
L
S
G
N
A
A
I
P
G
V
D
S
--
R
R
--
K
V
M
A
Q
L
T
G
R
R
I
V
Q
M
V
K
D
--
D
L
------
K
---
P
-
S
E
I
M
---
T
--
K
Q
A
F
E
----
N
A
-
I
R
T
N
A
A
I
G
G
S
T
N
A
V
I
H
--
L
L
A
I
A
G
R
V
G
I
D
--------
L
S
L
D
D
W
D
R
C
G
R
D
V
P
--
T
I
V
N
L
M
-
P
S
G
K
Y
L
M
E
E
-
F
F
Y
A
G
G
--
L
P
V
V
L
K
R
--
L
G
----
E
A
G
L
L
H
K
D
A
L
T
-----
V
S
G
E
T
V
-
W
D
E
V
K
D
----------------------------------
V
V
N
W
N
E
D
-----
V
I
L
P
A
E
K
A
L
T
S
S
G
G
I
V
V
L
R
G
N
L
A
--
P
K
G
A
V
L
K
------
P
S
A
A
S
P
H
L
L
V
H
K
G
R
A
V
------
V
F
E
D
I
-
D
D
Y
-----
K
A
K
I
ND
D
N
--
L
--
D
I
D
E
N
C
-
I
M
V
M
K
N
C
G
P
K
G
-
Y
P
G
M
A
E
V
G
N
---
M
G
L
P
P
K
-
V
L
K
K
G
I
L
D
M
V
--
R
-
I
S
D
--------------
A
--
R
M
--------------
A
G
T
A
-----
Y
G
T
V
--
V
L
H
T
S
P
E
A
A
V
G
G
P
L
----
A
V
V
-----
K
N
-
G
D
M
I
E
L
D
V
P
N
------
R
R
L
-----------------------
H
L
D
-
I
S
D
-
E
E
L
A
-----------
R
R
L
A
E
W
Q
P
N
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
64.31
27%
-32
- C6 -
-
5J83
-
?
A:
[54-548]
----------------------------------------------------------------------------------------------------------------
P
V
I
G
I
L
N
T
W
S
--
D
M
T
P
C
N
G
H
L
R
E
L
A
E
K
V
K
A
G
V
W
E
A
G
G
----
F
-
P
L
E
V
P
V
F
S
---
A
S
E
N
T
F
R
-
P
T
A
M
M
-------
Y
R
N
L
A
A
L
-
A
V
E
E
A
I
--
R
---------
G
Q
P
M
D
G
---
C
V
L
L
V
G
C
D
-
T
----------------
T
P
S
L
---------------------------------
L
M
G
--
A
A
S
C
D
-
L
P
S
I
V
V
T
G
G
P
M
L
N
G
Y
F
R
G
E
R
-------
V
G
SG
T
H
L
W
K
F
S
-
E
M
V
-
K
A
G
-------
E
M
T
Q
A
E
-
F
L
E
A
E
A
S
M
S
R
S
-
S
G
T
C
N
T
M
G
T
-
A
S
T
M
A
-
S
M
A
E
A
L
G
M
------
A
L
S
G
N
A
A
I
P
G
V
D
S
--
R
R
--
K
V
M
A
Q
L
T
G
R
R
I
V
Q
M
V
K
D
--
D
L
------
K
---
P
-
S
E
I
M
---
T
--
K
Q
A
F
E
----
N
A
-
I
R
T
N
A
A
I
G
G
S
T
N
A
V
I
H
--
L
L
A
I
A
G
R
V
G
I
D
--------
L
S
L
D
D
W
D
R
C
G
R
D
V
P
--
T
I
V
N
L
M
-
P
S
G
K
Y
L
M
E
E
-
F
F
Y
A
G
G
--
L
P
V
V
L
K
R
--
L
G
----
E
A
G
L
L
H
K
D
A
L
T
-----
V
S
G
E
T
V
-
W
D
E
V
K
D
----------------------------------
V
V
N
W
N
E
D
-----
V
I
L
P
A
E
K
A
L
T
S
S
G
G
I
V
V
L
R
G
N
L
A
--
P
K
G
A
V
L
K
------
P
S
A
A
S
P
H
L
L
V
H
K
G
R
A
V
------
V
F
E
D
I
-
D
D
Y
-----
K
A
K
I
ND
D
N
--
L
--
D
I
D
E
N
C
-
I
M
V
M
K
N
C
G
P
K
G
-
Y
P
G
M
A
E
V
G
N
---
M
G
L
P
P
K
-
V
L
K
K
G
I
L
D
M
V
--
R
-
I
S
D
--------------
A
--
R
M
--------------
S
G
T
A
-----
Y
G
T
V
--
V
L
H
T
S
P
E
A
A
V
G
G
P
L
----
A
V
V
-----
K
N
-
G
D
M
I
E
L
D
V
P
N
------
R
R
L
-----------------------
H
L
D
-
I
S
D
-
E
E
L
A
-----------
R
R
L
A
E
W
Q
P
N
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
63.66
25%
-3
- C6 -
-
5J84
2
?
H:
[14-579]
-------------------------------------------------
A
--
E
W
P
R
K
L
R
S
Q
E
--
W
Y
G
G
T
S
---
R
D
V
I
Y
H
R
--
G
W
L
K
----------
N
Q
G
Y
P
-
H
D
---
L
F
D
G
R
P
V
I
G
I
L
N
T
W
S
--
D
M
T
P
C
N
G
H
L
R
E
L
A
E
K
V
K
A
G
V
W
E
A
G
G
F
--
P
L
-
E
V
P
V
F
S
A
S
E
N
T
F
R
P
T
------
A
M
M
-------
Y
R
N
L
A
A
L
-
A
V
E
E
A
I
--
R
---------
G
Q
P
M
D
G
---
C
V
L
L
V
G
C
D
-
T
----------------
T
P
S
L
---------------------------------
L
M
G
--
A
A
S
C
-
D
L
P
S
I
V
V
T
G
G
P
M
L
N
G
Y
F
R
G
E
R
VGSGTHL
W
-------
K
F
S
-
E
M
V
-
K
A
G
-------
E
M
T
Q
A
E
-
F
L
E
A
E
A
S
M
S
R
S
-
S
G
T
C
N
T
M
G
T
-
A
S
T
M
A
-
S
M
A
E
A
L
G
M
------
A
L
S
G
N
A
A
I
P
G
V
D
S
--
R
R
--
K
V
M
A
Q
L
T
G
R
R
I
V
Q
M
V
K
---
D
D
------
L
---
K
P
S
E
I
M
---
T
--
K
Q
A
F
E
----
N
A
-
I
R
T
N
A
A
I
G
G
S
T
N
A
V
I
H
--
L
L
A
I
A
G
R
V
G
I
D
--------
L
S
L
D
D
W
D
R
C
G
R
D
V
P
--
T
I
V
N
L
M
-
P
S
G
K
Y
L
M
E
E
-
F
F
Y
A
G
G
--
L
P
V
V
L
K
R
--
L
G
----
E
A
G
L
L
H
K
D
A
L
T
-----
V
S
G
E
T
V
W
D
E
V
K
D
V
V
-----------------------------------
N
W
N
E
D
-----
V
I
L
P
A
E
K
A
L
T
S
S
G
G
I
V
V
L
R
G
N
L
A
PK
G
--
A
V
L
K
------
P
S
A
A
S
P
H
L
L
V
H
K
G
R
A
V
------
V
F
E
D
I
-
D
D
Y
-----
K
A
K
I
--
N
D
DN
L
--
D
I
D
E
N
C
-
I
M
V
M
K
N
C
G
P
K
G
Y
P
-
G
M
A
E
V
G
N
MGL
P
P
K
V
L
K
---
K
G
I
L
D
M
V
---
R
-
I
S
D
--------------
A
--
R
M
--------------
S
G
-
T
-----
A
-
Y
G
T
V
V
L
H
T
S
P
E
A
A
V
G
G
P
L
----
A
V
V
-----
K
N
-
G
D
M
I
E
L
D
V
P
N
------
R
R
L
-----------------------
H
L
D
-
I
-
S
-
D
E
E
L
-----------
A
R
R
L
A
-
E
W
Q
P
N
H
---
D
L
P
T
S
G
Y
A
F
L
H
Q
Q
H
V
E
G
A
D
T
G
A
D
L
D
F
L
K
G
C
R
--------------------------------------------------------------------------------------------------------------------------
30
HHSearch
63.01
25%
-6
- C6 -
-
5J85
1
?
A:
[13-579]
-------------------------------------
K
-----------
A
--
E
W
P
R
K
L
R
S
Q
E
--
W
Y
G
G
T
S
R
---
D
V
I
Y
H
R
--
G
W
L
K
----------
N
Q
G
Y
P
-
H
D
---
L
F
D
G
R
P
V
I
G
I
L
N
T
W
S
--
D
M
T
P
C
N
G
H
L
R
E
L
A
E
K
V
K
A
G
V
W
E
A
G
G
F
--
P
L
-
E
V
P
V
F
S
A
S
E
N
T
F
R
P
------
T
A
M
M
-------
Y
R
N
L
A
A
L
-
A
V
E
E
A
I
--
R
---------
G
Q
P
M
D
G
---
C
V
L
L
V
G
C
D
-
T
----------------
T
P
S
L
---------------------------------
L
M
G
--
A
A
S
C
-
D
L
P
S
I
V
V
T
G
G
P
M
L
N
G
Y
F
R
G
E
R
V
G
SGTH
L
W
-------
K
F
S
-
E
M
V
-
K
A
G
-------
E
M
T
Q
A
E
-
F
L
E
A
E
A
S
M
S
R
S
-
S
G
T
C
N
T
M
G
T
-
A
S
T
M
A
-
S
M
A
E
A
L
G
M
------
A
L
S
G
N
A
A
I
P
G
V
D
S
--
R
R
--
K
V
M
A
Q
L
T
G
R
R
I
V
Q
M
V
K
---
D
D
------
L
---
K
P
S
E
I
M
---
T
--
K
Q
A
F
E
----
N
A
-
I
R
T
N
A
A
I
G
G
S
T
N
A
V
I
H
--
L
L
A
I
A
G
R
V
G
I
D
--------
L
S
L
D
D
W
D
R
C
G
R
D
V
P
--
T
I
V
N
L
M
-
P
S
G
K
Y
L
M
E
E
-
F
F
Y
A
G
G
--
L
P
V
V
L
K
R
--
L
G
----
E
A
G
L
L
H
K
D
A
L
T
-----
V
S
G
E
T
V
W
D
E
V
K
D
V
V
-----------------------------------
N
W
N
E
D
-----
V
I
L
P
A
E
K
A
L
T
S
S
G
G
I
V
V
L
R
G
N
L
A
PK
G
--
A
V
L
K
------
P
S
A
A
S
P
H
L
L
V
H
K
G
R
A
V
------
V
F
E
D
I
-
D
D
Y
-----
K
A
K
I
--
N
D
--
D
NL
D
I
D
E
N
C
-
I
M
V
M
K
N
C
G
P
K
G
Y
P
-
G
M
A
E
V
G
N
MGL
P
P
K
V
L
K
---
K
G
I
L
D
M
V
---
R
-
I
S
D
--------------
A
--
R
M
--------------
A
G
-
T
-----
A
-
Y
G
T
V
V
L
H
T
S
P
E
A
A
V
G
G
P
L
----
A
V
V
-----
K
N
-
G
D
M
I
E
L
D
V
P
N
------
R
R
L
-----------------------
H
L
D
-
I
-
S
-
D
E
E
L
-----------
A
R
R
L
A
-
E
W
Q
P
N
H
---
D
L
P
T
S
G
Y
A
F
L
H
Q
Q
H
V
E
G
A
D
T
G
A
D
L
D
F
L
K
G
C
R
--------------------------------------------------------------------------------------------------------------------------
44
Fugue
38.62
16%
11
- C5 -
-
4NFU
3
EDS1L_ARATH
A:
[15-633]
-----------------------
A
----
F
E
A
L
T
G
-
I
N
G
D
L
I
T
R
S
-
W
S
A
S
K
--
Q
A
Y
L
T
E
R
Y
H
K
--
E
E
A
----
G
A
V
V
I
F
A
F
Q
--
P
S
F
---------------
S
E
K
D
F
F
D
P
D
N
-
K
S
S
F
G
E
I
K
-----------
L
N
R
V
Q
F
P
C
M
R
K
I
G
K
G
D
V
A
T
V
N
E
A
F
-
L
K
N
L
E
A
V
I
D
P
R
T
S
F
Q
A
S
V
-
E
M
A
V
R
-------
S
R
K
Q
I
V
F
T
G
H
S
S
G
G
--
A
---------
T
A
I
L
A
T
---
V
W
Y
L
E
K
Y
F
I
R
----------------
N
P
N
V
---------------------------------
Y
L
E
P
R
C
V
T
F
G
A
---
P
L
V
G
D
S
I
F
S
H
A
L
G
R
E
K
W
-------
S
-------
R
F
F
-
V
N
F
-
V
T
R
FDIVPRI
T
L
A
R
K
A
-
S
V
E
E
T
L
P
H
V
L
A
-
Q
L
D
P
R
N
S
S
V
-
Q
E
S
E
Q
-
R
I
T
E
F
Y
T
S
------
V
M
R
D
T
S
T
V
A
N
Q
A
V
--
C
E
--
L
T
G
S
A
E
A
I
L
E
T
L
S
S
F
L
E
L
S
P
Y
------
R
---
P
A
G
T
F
V
F
S
T
E
--
K
R
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I
--------
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--
M
K
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----
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K
K
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-----
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Q
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Q
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K
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---
G
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L
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N
--
G
M
--------------
I
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KGKPY
E
E
V
-----------------------
E
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R
-
V
-
K
-
T
L
E
G
-----------
M
L
R
E
W
I
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A
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D
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K
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F
L
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W
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L
P
K
N
H
K
S
H
S
P
L
R
D
Y
M
M
D
E
I
------------------------------------------------------------------------------------------------------------------------
48
Fugue
34.55
17%
15
- C3 -
-
5H8Y
2
SIR_MAIZE
D:
[11-576]
-------------------------------------
K
R
S
K
V
E
I
-
I
K
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K
--
S
N
F
L
R
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----------
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---
N
M
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---------------------------
T
L
G
A
C
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L
----------------------------------------------------------------
N
R
N
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A
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Q
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F
N
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------------------------------------------
G
-
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G
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K
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-----------------------
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S
F
T
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R
T
G
F
D
K
L
K
E
V
V
N
K
W-------------------------------------------------------------------------------------------------------------
51
Fugue
34.25
14%
-29
- C1 -
-
5LJ3
-
CLF1_YEAST
S:
[37-556]
-----------------------------
I
L
D
L
E
-
E
L
R
E
Y
Q
R
R
K
-
R
T
-
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--
E
G
Y
L
K
R
-------------------------------------------------------------------------
N
R
L
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G
Q
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Y
A
Q
F
E
I
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Q
-------------------
H
D
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---------
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---
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A
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------
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----
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----
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------------
V
P
K
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K
I
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K
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T
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K
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L
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---
I
W
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G
-
E
L
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N
G
--------------------------------------------------------------------------------------------
D
W
D
R
V
R
------
G
I
Y
-----------------------
T
I
A
-
L
-
D
-
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-------------
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A
K
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L
L
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K
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R
Y
L
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L
N
P
Q
S
W
I
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F
A
M
Y
Q
T
----------------------------------------------------------------------------------------------------------------------------------
43
Fugue
33.65
21%
-7
- C5 -
-
4Q2C
-
?
A:
[24-949]
G
S
P
V
G
A
A
G
W
R
VDPWIFWA
K
W
G
S
G
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G
W
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E
---
Q
L
G
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V
---
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--
G
Q
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----
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----
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--
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C
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------
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A
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---
A
I
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A
T
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Q
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D
L
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L
M
V
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D
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V
D
L
V
L
Q
R
M
G
RL
H
--
R
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--------------
P
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-
H
-----
D
P
L
R
P
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R
L
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P
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L
W
V
V
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-------------
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G
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F
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------
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Y
D
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H
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L
L
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W
L
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P
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R
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GR
W
I
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G
I
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V
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S
P
46
Fugue
32.58
16%
-47
- C5 -
-
5MPD
-
RPN3_YEAST
S:
[18-492]
----------------------------------------
L
H
H
S
-
E
K
-
K
Y
--
A
E
E
D
Q
V
Q
E
L
L
--
K
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--
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I
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----------
S
L
K
D
L
S
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L
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--------
N
Q
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L
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F
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V
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N
L
L
K
F
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---
N
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K
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F
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Y
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---------
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L
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---
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F
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K
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-------------------
L
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---------------------------------
L
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--
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N
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K
V
V
I
P
N
L
L
C
Y
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--------------------------
R
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S
T
M
M
K
------
F
L
K
I
A
S
L
K
H
D
---------
N
E
T
K
A
M
L
I
N
L
I
L
R
D
F
L
N
N
G
E
V
------
D
---
S
A
S
D
F
I
---
S
--
K
L
E
Y
P
----
H
T
-
D
V
------
S
S
S
L
E
A
R
Y
--
F
F
Y
L
S
K
I
N
A
I
Q
--------
L
D
Y
---
S
T
A
N
E
Y
I
I
--
A
A
I
R
K
A
-
P
H
N
S
K
S
L
G
F
-
L
Q
Q
S
N
K
--
L
H
C
C
I
Q
L
--
L
M
GDIP
E
L
S
F
F
H
Q
S
N
M
Q
-----
K
S
L
L
P
Y
-
Y
H
L
T
K
A
V
K
L
-------------
G
D
L
K
K
-----
F
----
T
S
T
I
T
K
Y
K
Q
L
-----
L
L
K
D
---------
D
T
Y
Q
L
C
V
R
L
R
--
S
--
N
V
I
K
TG----
I
R
I
I
S
L
T
Y
K
K
I
S
L
R
D
I
------
C
L
K
-------------------------
L
N
L
D
S
-
E
Q
T
V
E
Y
M
V
S
R
A
----------------------------------
I
R
D
--------------
G
--
V
I
-----------------------------------
E
A
K
I
N
H
E
D
----
G
F
I
-----
E
T
-
T
E
L
L
N
I
Y
D
S
E
-------------------------------------------------------------
D
P
Q
Q
V
F
D
E
R
I
K
F
A
N
Q
L
H
D
E
Y
L
V
S
M
R
Y
P
E
D
K
K
T
Q
---------
Q
N
E
K
--------------------------------------------------------------------------------------------------------------------
34
HHSearch
30.68
21%
-74
- C6 -
-
5FBS
-
?
A:
[774-865]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
E
G
R
A
R
------
V
I
L
E
M
-
E
K
----------------
A
--
D
L
E
D
G
D
-
I
L
V
T
A
Y
T
D
P
S
W
T
P
-
A
F
V
S
I
--------------------
K
G
--
L
-
V
T
E
--------------
V
GG
L
M
--------------
T
H
-
G
A
V
I
A
R
E
Y
G
L
P
A
V
V
G
V
------
E
N
A
T
----
T
I
I
-----
K
D
-
G
Q
Q
I
R
I
N
G
T
E
------
G
Y
I
-----------------------
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
29.47
16%
-52
* C5 *
-
2DRN
-
C:
[1-24]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
L
I
--
E
E
A
A
S
R
I
V
D
A
V
I
E
Q
V
K
A
A
G
A
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
27.87
12%
-185
- C6 -
-
1G8L
3
MOEA_ECOLI
A:
[159-192]
-----------------------------------------------------------------------------
A
E
L
--
P
V
I
A
----------
S
L
G
I
A
E
-
V
---
P
V
I
R
K
V
R
V
A
L
F
S
T
G
D
--
E
L
Q
L
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
27.70
22%
21
* C4 *
-
4R5O
3
?
A:
[2-427]
--------------------
D
D
C
E
----
D
L
H
L
G
N
-
L
A
-------------------
H
Y
P
N
V
L
--
K
G
T
F
P
T
E
S
-------------
Q
----------
V
L
E
L
G
E
T
L
E
I
T
P
E
L
-
L
N
P
E
G
A
T
Y
S
W
L
--
V
N
G
K
E
Y
S
T
E
P
T
F
S
Y
K
I
D
N
P
C
-----
R
-
A
D
L
-
S
C
I
I
K
N
------
K
Y
G
K
V
E
M
S
T
S
F
S
-------
S
N
H
N
F
S
K
-
G
F
F
Y
V
A
DG
T
---------
F
N
F
Y
D
T
---
E
K
--------------------------------------------------------------------
K
T
A
Y
Q
D
C
Y
A
S
L
N
A
G
K
T
L
G
I
G
N
Y
D
S
-------
A
-------
N
I
I
-
H
S
-----------------------------
N
-
G
K
F
Y
L
L
V
G
T
-
S
T
S
N
------------------------
R
D
H
F
Y
--
I
V
--
D
A
K
T
L
Y
-----------
Y
E
N
S
------
A
---
V
V
G
A
N
L
---
S
--
G
L
T
I
L
----
N
E
-
Q
Y
G
L
V
T
G
D
G
-----
I
R
--
R
I
D
L
K
S
L
N
N
V
R
--------
I
K
N
E
R
L
-----
L
C
F
--
Y
N
S
I
I
Y
--
N
G
K
V
L
S
N
D
T
Y
K
D
E
S
K
--
V
K
Y
Y
D
V
N
--
E
L
----
I
A
---------------
A
K
E
G
E
-
A
P
A
V
T
E
L
D
I
I
Q----------
K
Q
K
I
N
F
-----
V
L
A
K-
D
G
N
V
Y
T
L
E
S
A
-------------------------
D
N
G
--
C
--
N
I
V
K
------
I
K
--------------------------------------------------
N
D
F
-
T
L
E
K
V
F
A
N
F
Q
P
-
A
-
K
G
P
--
Y
H
---
S
S
P
T
I
G
M
V
A
S
E
T
E
N
I
I
Y
--
L
-
V
S
T
--------------
D
----------------------------
G
A
I
Y
K
Y
I
-
L
G
D
S
D
S
L
K
A
P
F
----
I
A
A
-----
E
S
-
G
--
V
S
I
T
A
P
----------------------------------
L
Q
-
L
-
N
-
Q
Q
S
G
-----------
E
L
Y
V
T
Y
T
E
E
R
K
D
E
S
K
I
V
V
Y
-------------
S
K
D
G
K
V
L
H
T
V
D
C
G
E
S
V
P
S
Q
I
L
F
NN----------------------------------------------------------------------------------------------------------------
35
HHSearch
26.94
17%
-26
- C6 -
-
3K4I
-
?
C:
[75-176]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
Y
I
--
D
------
Q
V
P
S
G
S
-
V
I
V
S
S
N
S
G
R
H
D
C
T
-
V
W
G
D
I
M
T
---
H
-
F
A
L
A
---
N
G
---
I
K
G
--
T
-
V
I
D
--------------
G
--
V
A
R
D
I
D
T
V
I
N
C
NYPLF
S
R
-
G
-----
R
F
M
Q
S
A
K
N
R
T
Q
L
-
K
A
V
Q
V
P
L
V
I
DG
I
T
I
-----
Q
P
-
G
D
L
M
V
C
D
G
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
25.38
16%
13
- C4 -
-
5I5H
-
YEJM_ECOLI
A:
[246-572]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
L
S
E
--
L
R
YR
D
M
G
T
G
Q
---
N
V
L
L
I
T
V
D
G
L
N
Y
------
S
---
R
F
E
K
Q
M
---
P
--
A
L
A
G
F
----
A
E
-
Q
N
I
S
F
T
R
H
M
S
S
G
N
T
T
D
--
N
G
I
F
G
L
F
Y
G
I
S
--------
P
S
Y
M
D
G
I
L
S
T
R
T
P
A
--
A
L
I
T
A
L
-
N
Q
Q
G
Y
Q
L
G
L
-
F
S
S
D
G
F
--
T
S
P
L
Y
R
Q
--
A
L
----
L
S
D
F
S
M
P
S
V
R
T
QS
D
E
Q
T
A
T
Q
W
I
-
N
W
L
G
R
Y
A
Q
E
D
-----------
N
R
W
F
S
W
-----
V
----
S
F
N
G
T
N
I
D
D
S
-----
N
Q
Q
A
F
A
R
K
Y
S
R
A
A
G
------
N
V
D
--
D
--
Q
I
N
R
------
V
L
N
A
L
R
D
S
G
K
L
D
N
T
V
V
------
I
I
T
A
G
-
R
G
I
P
LSEE
E
E
T
F
--
D
W
--
S
--
H
G
H
L
Q
V
-
P
L
V
I
H
W
P
G
T
P
A
-
Q
-
R
I
N
A
L
T
D
---
H
T
D
L
M
T
-
T
L
M
Q
R
L
L
H
V
S
--
T
-
P
A
S
--------------
E
--
Y
S
--------------
Q
G
-
Q
-----
D
L
F
N
P
Q
R
R
H
Y
W
V
T
A
A
D
N
D
T
L
----
A
I
T
-----
T
P
-
K
K
T
L
V
L
N
N
N
G
------
K
Y
R
-----------------------
T
Y
N
-
L
-
R
G
E
R
V
K
-----------
D
E
K
P
Q
L
S
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
24.03
23%
-46
- C6 -
-
5HV3
-
?
A:
[786-877]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
E
G
R
A
R
------
V
I
L
E
M
-
E
K
----------------
A
--
D
L
E
D
G
D
-
I
L
V
T
A
Y
T
D
P
S
W
T
P
-
A
F
V
S
I
--------------------
K
G
--
L
-
V
T
E
VG------------
G
--
L
M
--------------
T
H
-
G
A
V
I
A
R
E
Y
G
L
P
A
V
V
G
V
------
E
N
A
T
----
T
I
I
-----
K
D
-
G
Q
Q
I
R
I
N
G
T
E
------
G
Y
I
-----------------------
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
23.62
24%
-2
- C7 -
-
1MJ1
-
EFTU1_ECOLI (first)
A:
[71-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
A
K
R
H
Y
S
H
V
D
C
R
G
H
A
------
D
---
Y
I
K
N
M
I
---
T
--
G
A
A
Q
M
----
D
G
A
I
L
V
V
S
A
A
D
G
R
M
R
Q
T
R
E
--
H
I
L
L
A
R
Q
V
G
V
R
Y
I
V
V
F
MNK
V
D
M
V
D
D
R
E
L
L
D
L
V
E
--
M
E
V
R
D
L
-------
L
N
Q
-
Y
E
F
R
G
D
--
E
V
R
V
I
R
G
S
A
L
L
----
A
L
E
E
M
H
K
N
R
K
T
-----
K
R
G
E
N
--
E
W
V
D
K
I
W
E
L
L
-----------
D
A
I
D
E
Y
-----
I
----
R
T
R
V
R
D
V
D
K
R
-----
F
L
M
R
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
--
R
--
G
K
V
K
VG
D
E
V
E
I
V
G
L
A
R
E
T
R
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------