@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKV1: (2017-10-29 )
MLKRIAVTALCVASLSGCASFISGGTGTAPVGTDSGVRSLGQVFIDSSIKRTANINLYKLDQRFKQSRINIESFHSTVLLTGQVPDPYLKQLAEDNVKAMSDVKAVHNYITVGNKVSYNTIMQDAGVTANTRALLMKAPVVSDSKVLVHTEDGVLYVMGRLNTAEINDLNNVLQNVGNVTKIVTLIDNIDLAPAPAASTASATTTPVINNVLAQPTVQTPVAIDPGQTDPASFAQ
Atome Classification :
(20 SA)
---------.........10........20...-.....30.....-...40-------........50........60.....--...70..-.--.-....80.........90.------......-.-100........--110-------.-.....--..120.....------..130.......140---.........150-----....-..-.-160..---.-----....-----170..-.-.---------------------------...180-----....--..-..190---...-....200-----------........-.210.......220...--....230...-----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------ML
K
R
I
A
V
T
A
L
C
V
A
S
L
S
G
C
A
S
F
ISG-GTGTAPVG
T
D
S
G
-
V
R
S
L
G
-------
Q
V
F
I
D
SSIKRTANI
N
L
Y
K
L
D
Q
R
F
K
Q
--SRI
N
I
E
S-F--
H
-
S
T
V
L
L
-TGQVP
D
P
Y
L
K
Q
L
------
A
E
D
N
V
K
-
A
-
M
-
S
D
V
K
A
V
H
N
Y
--IT--------V-GNKV
S
--
Y
N
T
I
M
QDAGV------TAN
T
R
A
L
L
M
KAPV-----VSD
S
K
V
L
V
HTED-----
G
V
L
Y
-
V
M
-G-RLNTA---
E
-----
I
N
D
L
-----
N
N
V
L
Q
-N-V---------------------------G
N
V
T
K
------
I
V
T
L
--ID-NIDLA---PAP-AASTA-------------SATT
T
P
V
I
-
N
N
V
LAQPTVQT
P
V
A
IDP--GQTDPASFAQ-----------------------------------
32
HHSearch
76.20
15%
-82
- C3 -
-
4QO6
2
?
A:
[68-204]
------------------------------------------------------------
V
I
D
D
E
A
V
W
Q
E
M
N
I
L
L
S
K
N
P
-
E
F
K
G
--
I
S
M
Q
S
P
E
----
P
-
G
I
F
V
I
-
S
G
Y
L
K
T
E
E
Q
A
A
C
------
L
A
D
Y
L
N
-
L
H
F
-
N
Y
L
S
L
L
D
N
K
--
V
I
--------
I
-
E
-------------
S
Q
V
------
M
K
A
L
A
G
H
L
V
Q
S
G
------
F
A
--
N
V
H
V
S
F
T
N
-----
G
E
A
V
-
L
T
-
G
-
Y
I
N
N
K
D
A
D
K
-----
F
R
T
V
-----
V
Q
E
L
Q
-
D
-
I
---------------------------
A
G
I
R
A
------
V
K
N
F
--
V
V
-
L
L
P
A
---------------------------------------------------------------------------------------------------
26
Fugue
71.63
15%
27
- C3 -
-
4QO6
3
?
A:
[9-217]
I
D
L
I
H
D
I
E
H
V
I
Q
Q
F
P
T
V
R
F
T
F
N
K
N
N
G
Q
L
F
L
I
G
H
V
R
N
S
I
D
K
S
E
L
L
Y
K
-
V
D
A
L
S
FVKSVDD
N
V
I
D
D
E
A
V
W
Q
E
M
N
I
L
L
S
K
-
N
P
E
F
K
G
--
I
S
M
Q
S
P
E
----
P
-
G
I
F
V
I
-
S
G
Y
L
K
T
E
E
Q
A
A
C
------
L
A
D
Y
L
N
-
L
H
F
-
N
Y
L
S
L
L
D
N
K
--
V
I
--------
I
--------------
E
S
Q
V
------
M
K
A
L
A
G
H
L
V
Q
S
G
F
--------
A
N
V
H
V
S
F
T
N
-----
G
E
A
V
-
L
T
-
G
-
Y
I
N
N
K
---
D
-----
A
D
K
F
-----
R
T
V
V
Q
-
E
-
L
---------------------------
Q
D
I
A
G
------
I
R
A
V
--
K
N
-
F
V
V
L
L
---
P
A
E
-
E
G
V
I
D
-------------
L
N
M
R
Y
P
G
------------------------------------------------------------------
33
HHSearch
69.89
15%
-63
- C3 -
-
4QQ0
-
?
A:
[114-249]
------------------------------------------------------------
V
I
D
D
E
A
V
W
Q
E
M
N
I
L
L
S
K
N
P
-
E
F
K
G
--
I
S
M
Q
S
P
E
----
P
-
G
I
F
V
I
-
S
G
Y
L
K
T
E
E
Q
A
A
C
------
L
A
D
Y
L
N
-
L
H
F
-
N
Y
L
S
L
L
D
N
K
--
V
I
--------
I
-
E
-------------
S
Q
V
------
M
K
A
L
A
G
H
L
V
Q
S
G
------
F
A
--
N
V
H
V
S
F
T
N
-----
G
E
A
V
-
L
T
-
G
-
Y
I
N
N
K
D
A
D
K
-----
F
R
T
V
-----
V
Q
E
L
Q
-
D
-
I
---------------------------
A
G
I
R
A
------
V
K
N
F
--
V
V
-
L
L
P
----------------------------------------------------------------------------------------------------
35
HHSearch
63.82
17%
3
- C3 -
-
4QQ0
-
?
A:
[56-197]
-----------------------------------------------------------------
D
L
I
H
D
I
E
H
V
I
Q
Q
F
--------
P
T
V
R
F
T
F
-
N
KN
N
-
G
Q
L
F
L
-
I
G
H
V
R
N
S
I
D
K
S
E
------
L
L
Y
K
V
D
-
A
-
L
-
S
F
V
K
S
V
D
D
N
------------------------
V
I
D
D
E
A
V
------
W
Q
E
M
N
I
L
L
S
K
N
P
E
-----
F
K
G
I
S
M
Q
S
P
E
-
P
-----
G
I
F
V
-
I
S
-
G
-
Y
L
K
T
E
E
--
Q
-----
A
A
C
L
-----
A
D
Y
L
N
-
L
H
F
---------------------------
N
Y
L
S
L
------
L
D
N
K
--
V
I
-
I
E
----------------------------
S
Q
V
M
K
A
L
A
-
G
H
L
V
Q
S
----------------------------------------------------------
21
Fugue
59.79
16%
24
- C3 -
-
5JJ6
-
FICD_CAEEL
A:
[19-352]
-----KEAI
L
A
A
K
A
A
G
R
S
R
K
D
G
N
L
E
R
A
M
T
I
M
E
H
-
A
M
A
L
A
P
T
N
---------
P
-------
Q
I
L
I
E
M
G
Q
I
R
E
M
H
N
E
L
V
E
A
D
Q
C
Y
V
K
--
A
L
A
Y
-
D
P
-
G
--
N
-
S
E
A
L
V
-
L
R
A
R
T
T
P
L
V
S
A
I
------
D
R
K
M
L
R
-
S
-
V
-
H
D
L
R
D
E
F
N
H
--
L
Q
H
S
T
A
L
R
R
-
M
-
M
R
E
T
Y
--
F
L
Y
V
Y
H
T
V
A
I
E
GNTLS
L
G
Q
T
R
A
I
L
E
S
G
M
V
I
P
GKS
I
R
E
H
N
E
V
I
G
M
D
A
-----
A
L
R
F
-
L
N
-
C
-
S
L
L
S
K
---
E
HDEIS
I
D
D
I
-----
L
E
M
H
R
-
R
-
V
L
GNADPVEAGRIRTTQVYTPVSPEYV
M
E
Q
L
K
D
------
I
V
D
W
--
L
N
-
D
E
S
T
L
T
ID
P
I
E
-
R
A
A
I
A
H
Y
K
L
V
L
V
HPFTDG
N
G
R
T
A
R
L
L
-
L
N
L
I
M
M
R
S
G
F
P
P
V
I
L
-
P
--
V
E
T
R
A
E
Y
Y
A
S
L
H
V
A
N
L
GDL
R
P
F
V
R
Y
V
A
K
H
S
E
A
S
I
Q
R
Y
I
G
A
M
K
T
S
S
4
PsiBlast_PDB
58.93
22%
-86
- C5 -
-
1FYH
-
INGR1_HUMAN
B:
[87-208]
--------------------------------------
A
R
V
G
Q
K
E
S
-
A
Y
A
K
S
-------
E
E
F
---
A
V
C
R
D
G
K
I
G
P
P
K
L
D
I
R
K
E
E
--
K
Q
I
M
I
D
I
-
F
--
H
-
P
S
V
F
V
------------------------
E
-
T
-
T
-
C
Y
I
R
V
Y
N
V
Y
--
V
R
--------
M
N
G
S
E
I
Q
--
Y
K
I
L
T
Q
K
E
D
D
------
C
D
E
I
Q
C
Q
L
A
-
I
P
V
-----
S
S
L
N
S
Q
Y
C
V
S
A
E
-----
G
V
L
H
-
V
W
-
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
58.55
19%
5
- C3 -
-
2KGS
-
ARFA_MYCTU
A:
[76-200]
--------------------------------------------------------------------------------
A
L
S
L
--
S
L
L
S
I
S
R
-
S
--
G
-
N
T
V
T
L
-
I
G
D
F
P
D
E
A
A
K
A
A
------
L
M
T
A
L
N
-
G
-
L
L
A
P
G
V
N
V
I
D
Q
--
I
H
--------
V
-
D
P
V
V
R
--
S
L
D
-----
F
S
------
S
A
-
E
P
-
V
F
T
A
S
-------
V
P
I
P
D
F
G
L
K
V
E
R
-----
D
T
V
T
-
L
T
-
G
-
T
A
P
S
S
E
--
H
-----
K
D
A
V
-----
K
R
A
A
T
-
S
-
T
---------------------------
W
P
D
M
K
------
I
V
N
N
--
I
E
-
V
T
G
Q
A
---
P
P
---------------------------------------------------------------------------------------------
30
Fugue
58.03
16%
43
- C3 -
-
2MHK
-
LPOA_ECOLI
A:
[1-250]
------MGS
S
H
H
H
H
H
H
S
S
G
L
V
P
R
G
S
H
M
G
T
H
T
P
D
-
Q
S
T
A
Y
M
Q
G
T
A
Q
A
D
S
A
F
Y
L
-------
Q
Q
M
Q
Q
S
S
D
D
T
R
I
N
W
Q
L
L
A
I
R
A
L
V
K
E
GK
T
G
Q
A
V
E
L
-
F
--
N
-
Q
L
P
Q
E
-
L
N
D
A
Q
R
R
E
K
T
L
L
------
A
V
E
I
K
L
-
A
-
Q
-
K
D
F
A
G
A
Q
N
L
--
L
A
K
ITPADLE
Q
-
N
Q
Q
A
R
--
Y
W
Q
A
K
I
D
A
S
Q
GRPS--
I
D
L
L
R
A
L
I
A
Q
E
P
L
-----
L
G
-
A
K
E
K
Q
Q
N
I
D
-----
A
T
W
Q
-
A
L
-
S
-
S
M
T
Q
E
---
Q
-----
A
N
T
L
V
I
N
AD
E
N
I
L
Q
-
G
-
W
---------------------------
L
D
L
Q
R
------
V
W
F
D
--
N
R
-
N
---
D
---
P
D
M
-
M
K
A
G
I
-------------
A
D
W
Q
K
R
Y
P
-
N
N
P
G
A
K
M
L
P
T
Q
L
V
N
V
K
A
--
F
K
P
A
S
T
---------------------------------------
34
HHSearch
57.51
18%
13
- C3 -
-
4QO6
3
?
A:
[23-152]
--------------------------------------------------------------------------------------
P
T
V
R
F
T
F
-
N
KN
N
-
G
Q
L
F
L
-
I
G
H
V
R
N
S
I
D
K
S
E
------
L
L
Y
K
V
D
-
A
-
L
-
S
F
V
K
S
V
D
D
N
------------------------
V
I
D
D
E
A
V
------
W
Q
E
M
N
I
L
L
S
K
N
P
E
-----
F
K
G
I
S
M
Q
S
P
E
-
P
-----
G
I
F
V
-
I
S
-
G
-
Y
L
K
T
E
E
--
Q
-----
A
A
C
L
-----
A
D
Y
L
N
-
L
H
F
---------------------------
N
Y
L
S
L
------
L
D
N
K
--
V
I
-
I
E
----------------------------
S
Q
V
M
K
A
L
A
-
G
H
L
V
Q
S
G
---------------------------------------------------------
22
Fugue
56.70
19%
-93
- C3 -
-
5KES
-
DDI1_YEAST
A:
[1-116]
-----------------------------------------------------------------
G
P
L
G
S
A
T
L
S
D
E
A
F
I
E
Q
F
R
Q
--
E
L
L
N
N
Q
M
-
L
--
R
-
S
Q
L
I
L
-
Q
----
I
P
G
L
N
D
L
------
V
N
D
P
L
L
-
F
-
R
-
E
R
L
G
P
L
I
L
Q
--
R
R
--------
Y
-
G
G
-----
Y
N
T
A
M
N
P
F
G
I
------
P
Q
D
E
Y
T
R
L
M
A
N
P
D
-----
D
P
D
N
K
K
R
I
A
E
L
L
-----
D
Q
Q
A
-
I
D
-
E
-
Q
L
R
N
A
---
I
-----
E
Y
T
P
-----
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
56.42
22%
-70
- C5 -
-
1FG9
-
INGR1_HUMAN
C:
[87-208]
--------------------------------------
A
R
V
G
Q
K
E
S
-
A
Y
A
K
S
-------
E
E
F
---
A
V
C
R
D
G
K
I
G
P
P
K
L
D
I
R
K
E
E
--
K
Q
I
M
I
D
I
-
F
--
H
-
P
S
V
F
V
-
N
G
D
------
E
Q
E
---------
D
P
E
-
T
-
T
-
C
Y
I
R
V
Y
N
V
Y
--
V
R
--------
M
N
G
S
E
I
Q
--
Y
K
I
L
T
Q
K
E
D
D
------
C
D
E
I
Q
C
Q
L
A
-
I
P
V
-----
S
S
L
N
S
Q
Y
C
V
S
A
E
-----
G
V
L
H
-
V
W
-
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
54.22
12%
-9
* C3 *
-
4ALZ
-
A:
[5-134]
----------------------------------------------------------------
Q
L
V
E
Q
E
V
R
R
L
L
A
T
A
----
A
Y
--
K
D
V
V
L
T
S
P
K
--
E
G
E
P
W
L
L
-
T
G
Y
I
Q
D
N
H
A
R
L
S
------
L
Q
N
F
L
E
-
S
-
H
--
G
I
P
-
F
R
L
------------------------
E
L
R
S
M
E
E
L
------
R
Q
G
A
E
F
I
L
Q
R
L
-
G
-----
Y
H
G
I
E
V
S
L
A
P
Q
A
-----
G
W
L
Q
-
L
N
-
G
-
E
V
S
E
E
I
--
Q
-----
K
Q
K
I
-----
D
S
L
L
Q
A
E
-
V
---------------------------
P
G
L
L
G
------
V
E
N
K
--
V
R
-
I
A
P
----------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
53.52
37%
-16
- C6 -
-
2H5U
1
LAC1_TRAMX
A:
[269-323]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
V
---------------------------
G
F
N
G
G
------
I
N
S
A
--
I
L
-
R
Y
D
G
A
---
P
A
V
-
E
P
T
T
N
-------------
Q
S
T
S
T
Q
P
L
-
N
E
T
N
L
H
P
L
V
S
T
P
V
P
G
S
P
AA
G
G
V
D
K
A
---------------------------------------
23
Fugue
53.30
21%
-27
- C3 -
-
1S12
-
?
A:
[1-94]
------------------------------------------------------------------------------------------------------------------------------------
M
-
I
K
V
T
V
T
N
S
F
--
F
E
--------
V
-
T
G
H
A
P
--
D
K
T
L
C
A
S
V
S
L
------
L
T
Q
H
V
A
N
F
L
K
A
---------
E
K
K
A
K
I
K
K
E
S
-----
G
Y
L
K
-
V
K
F
E
-
E
L
E
N
C
---
E
-----
V
K
V
L
-----
A
A
M
V
R
-
S
-
L
---------------------------
K
E
L
E
Q
K
F
P
SQ
I
R
V
E
V
--
I
D
-
N
G
S
----------------------------------------------------------------------------------------------------
37
HHSearch
52.93
17%
-35
- C3 -
-
4ALZ
1
YSCD_YEREN
A:
[63-182]
-----------------------------------------------------------
E
L
R
S
M
E
E
L
R
Q
G
A
E
F
I
L
Q
R
L
--
G
Y
H
G
--
I
E
V
S
L
A
P
-
Q
--
A
-
G
W
L
Q
L
-
N
G
E
V
S
E
E
I
Q
K
Q
K
------
I
D
S
L
L
Q
A
E
-
V
-
P
G
L
L
G
V
E
N
K
--
V
R
--------
I
-
A
P
N
-------------
Q
------
R
K
R
L
D
A
L
L
E
Q
F
G
------
L
-
D
S
D
F
T
V
N
V
K
G
-----
E
L
I
E
-
L
R
-
G
-
Q
V
N
D
E
---
K
-----
L
S
S
F
-----
N
Q
L
Q
Q
-
T
--------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
52.20
28%
32
- C4 -
-
5D00
1
BSHA_BACSU
A:
[133-246]
--------------------------------------------------------------------------------------------------------------
D
P
S
L
K
D
L
I
R
F
A
I
E
S
S
D
R
V
T
-
A
-
V
-
S
S
A
L
A
A
E
T
Y
D
L
I
K
--------
P
-
E
K
K
I
E
T
I
Y
N
F
I
-------------
K
N
T
A
A
I
K
E
K
H
G
I
-----
L
P
D
E
K
V
V
I
H
-------------
V
S
-
N
-
F
R
K
V
K
---
R
-----
V
Q
D
V
-----
I
R
V
F
R
-
N
-
I
---------------------------
A
G
K
T
K
------
A
K
L
L
--
L
-----
V
G
---
D
G
P
-
E
K
S
T
A
--------------------------------------------------------------------------------------
11
PsiBlast_PDB
52.02
37%
-9
- C6 -
-
3DIV
3
LAC1_TRAMX
A:
[269-323]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
V
---------------------------
G
F
N
G
G
------
I
N
S
A
--
I
L
-
R
Y
D
G
A
---
P
A
V
-
E
P
T
T
N
-------------
Q
T
T
S
V
K
P
L
-
N
E
V
N
L
H
P
L
V
S
T
P
V
P
G
S
P
SS
G
G
V
D
K
A
---------------------------------------
25
Fugue
51.06
11%
37
- C3 -
-
2GHP
-
PRP24_YEAST
A:
[41-291]
------T
T
V
L
V
K
N
L
P
K
S
Y
N
Q
N
K
V
Y
K
Y
F
K
H
C
--
G
-
P
I
I
H
V
D
V
A
D
S
L
K
--
K
N
F
R
-------
F
A
R
I
E
F
A
R
Y
D
G
A
L
A
A
I
T
K
T
H
K
V
V
G
Q
--
N
E
I
I
V
S
H
-
L
--
T
-
E
C
T
L
W
M
T
N
-
F
P
P
S
Y
T
Q
R
N
------
I
R
D
L
L
Q
-
D
-
I
-
N
V
V
-----
A
--
L
S
--------
I
-
R
L
P
R
R
--
F
A
Y
I
D
V
T
S
K
E
------
D
A
R
Y
C
V
E
K
L
N
G
L
K
-----
I
E
G
Y
T
L
V
T
K
V
S
N
PLTLE
G
R
E
I
M
I
R
-
N
L
S
T
E
L
L
---
D
-----
E
N
L
L
-----
R
E
S
F
E
-
G
-
F
---------------------------
G
S
I
E
K
------
I
N
I
P
--
A
G
Q
K
F
N
N
C
---
C
A
F
M
V
F
E
N
K
-------------
D
S
A
E
R
A
L
Q
M
N
R
S
L
L
G
N
---
R
E
I
S
V
S
L
--
A
D
K
K
P
----------------------------------------
17
PsiBlast_PDB
50.75
28%
-94
- C4 -
-
4WH2
3
NAHK_BIFL2
A:
[39-90]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
D
-----
G
P
R
Y
-
I
L
-
Q
-
Q
M
N
T
S
---
I
-----
F
P
D
T
-----
V
N
L
M
R
-
N
-
V
---------------------------
E
L
V
T
S
------
T
L
K
A
Q
G
K
E
-
T
L
D
I
V
---
P
T
T
-
S
G
A
T
---------------------------------------------------------------------------------------
16
PsiBlast_PDB
50.70
28%
-104
- C4 -
-
4WH1
-
NAHK_BIFL2
A:
[39-90]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
D
-----
G
P
R
Y
-
I
L
-
Q
-
Q
M
N
T
S
---
I
-----
F
P
D
T
-----
V
N
L
M
R
-
N
-
V
---------------------------
E
L
V
T
S
------
T
L
K
A
Q
G
K
E
-
T
L
D
I
V
---
P
T
T
-
S
G
A
T
---------------------------------------------------------------------------------------