@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKV8: (2017-10-30 )
MYKLTTFVWQPSAASLFKITVLSSALAALGITTGCSSTPQSAKTSKTKQVSGAGYLDASSLNSLEDLLSATDMRAVEGDRLLILKHGDVWKRMAVGFKMDLNHWDPRIEAQRSWFISRQPYLDRLSARASRYLYHTVKEAERRGLPTELALLPVIESSYDPAATSSAAAAGLWQFIPSTGRIYGLQQTGMYDGRRDVVESTRAAYEFLGSLYNQFGSWELALAAYNAGPGRIQQAINRNQAAGLPTDYWSLKLPQETMNYVPRFLAVAQIIKNPRAYGVSLPPIANRPHFREVTLSAPLSLNEIASVTGLSRAELYALNPGYRGETVDPASPMRILIPADISPSVDNKLKGMKAGGSSGWWASVTSPSKPTTTTSTSVTVRTTPSTPAQPVRPSTPAKTSSSSVTVKTATPRGSDALAAFAASADVPSAPRIPVAVTPAANIKPVRTEPPISATEREKILAAVRAEGEKETVDQALEPQATQAEKDQVVAELKALAPQGTEIVDPYDGKIKLTAIQTSQSVAEQQGKEVSKGFAYPKTLAEDATLANSEDAQRNKDKPYIKTDTDVVVVQPKGKRSTYTVQPGDTLAVIAMKNGVNWRDVAKWNQIDPEKTLFVGTSLYLYDAKPQEAETTAKSAAKPDVYVVQANDSLTGVANQFNLSVKQLAEYNDLSVTDGLFVGQKLQLKEPKGNRAAKVEPKAIQASTRRITTKSYTVKRGEYLKLIADRYALSNQELADLTPGLSAGSNLIVGQKINVPAKEITVDEVDDSKASGKYEKLAAGPSYKTESYKVQRGDTLSSIATKSKISLAELAELNNLKANSHVQLGQTLKVPAGASVPDQYVVQSGDSLNAIAAKYNLQTSYLADLNGLSRTAGLRTGQRLKLTGEVETTSKVSAKNTKEETPETYTVKSGDSLGNIANRYHLQLDYLAALNGLSRNSNVRVGQRLKLTGDLPTVETAKTDTAKSSPKAVVAGKNTEKYTVKAGESLNAIASRAGISVRELAEMNALKANANLQRGQNIVIPKTVVEYKVKRGDTLIGLASKYGLETTLLAELNNLTPSTQLRIGDIIKVPNL
Atome Classification :
(20 SA)
--.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......-150........160.......170.......180.......-----190.......200.......210....-------.--------..220.......230.......240------..-.....250-..---------------.------------------.-.....260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500-........510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690..---.....700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......---800.......810.......820.......830--.....---------------------.---------------------.840.......850....-...860....-...870.......880...--....890.......900-.......910.......920.......930.......940.......950.......960.......970.......980.......990.-......1000...-...1010......1020-------......1030......1040......1050......1060......1070
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--MY
K
L
T
T
F
V
WQPSAA
S
L
F
K
I
T
V
L
S
S
A
L
A
A
LGITTGCSSTPQSAKTSKTKQVSGAGYLD
A
S
S
L
N
S
L
E
D
L
L
S
ATDMRAVEG
D
R
L
L
I
L
KHG
D
V
W
K
R
M
AVG
F
K
M
DLNHWDP
R
I
E
A
Q
R
S
W
FISRQ
P
Y
L
D
R
L
S
A
R
A
S
R
Y
L
Y
H
T
V
K
E
A
E
RRGLPTE
L
-
A
L
-
L
PVIESSYDPAAT
S
S
A
A
A
A
G
L
W
Q
FIPST
G
R
I
Y
G
L
Q
QTG-----MYD
G
R
R
D
V
V
E
S
T
R
A
A
Y
E
F
L
G
S
L
Y
N
QFG-------S--------
W
E
L
A
L
A
AYNAG
P
G
R
I
Q
Q
A
I
NRNQAA------GL-PTD
Y
W
S
---
L
K---------------L------------------
P
-
Q
E
T
M
N
Y
V
P
R
F
L
A
V
A
Q
I
IKNPRAYGVSLPPIANRPH
F
R
E
V
TLSAPL
S
L
N
E
I
A
S
VTGL
S
R
A
E
L
Y
A
LNPGYRGETVDPAS
P
M
R
I
L
I
PADISPSV
D
N
K
L
K
G
MKAGGSSG
W
W
A
SVTSPSKPTTTTS
T
S
V
T
V
R
TTPSTPAQPVRPSTPAKTSS
S
S
V
T
V
K
TATPRG
S
D
A
L
A
A
F
AASADVPSAPRI
P
V
A
VTPAANIKPVRTEPPI
S
A
T
E
R
E
K
I
L
A
A
V
RAEG
E
K
E
T
V
D
Q
ALEPQAT
Q
A
E
K
D
Q
V
V
A
E
L
K
A
LAPQG
T
E
--IVDPYDG
K
I
K
L
T
A
I
QT
S
Q
S
V
A
E
Q
Q
G
K
E
V
SKGFAY
P
K
T
LAEDATLANSEDAQRNKDKPYIKTDT
D
V
V
V
VQPKGKR
S
T
Y
T
VQPG
D
T
L
A
V
I
A
MKNGV
N
W
R
D
VAKWNQIDPE
K
T
L
F
V
G
T
S
L
Y
L
YDAKPQ
E
A
E
TTAKSAAKP
D
V
Y
V
V
QANDSLTG
V
A
N
Q
F
N
L
S
V
K
Q
L
AEYNDLSVTDGLFVG
Q
K
L
Q
LKEPKGNRAAKV---E
P
K
A
IQAST
R
R
I
T
TK
S
Y
T
VKR
G
E
Y
L
K
L
I
A
D
R
YALSN
Q
E
L
A
D
LTPGLSAGS
N
L
I
VGQKINVPAK
E
I
T
V
DEVDDSKASGK
Y
E
KLAAGPSYKTE
S
Y
K
V
QRGD
T
L
S
S
I
A
---
T
KSK
I
S
L
A
E
L
A
E
L
NNLKANS
H
V
QLG
Q
T
LKVPAG--ASVP
D
---------------------
Q
---------------------
Y
VVQSGDSL
N
A
I
A
A
K
YNL-Q
T
S
Y
L
A
D
LNG-L
S
R
TAGLRTG
Q
R
L
K
L
T
G
EV--ETTSKVSAKNTKEETP
E
-
T
Y
T
VKSGDS
L
G
N
I
A
N
R
Y
H
L
Q
L
D
Y
L
A
A
LNGLSRNSN
V
R
VG
Q
R
L
K
LTGDLPTVETAKTDTAKSSP
K
A
V
V
AGKNT
E
K
Y
T
V
KAGE
S
L
N
A
I
A
S
RAG-
I
S
V
R
E
L
A
E
M
N
A
LK-ANANLQRG
Q
N
I
V
I
P
K
T
V
-------
V
E
Y
K
VKRG
D
T
L
I
G
L
A
S
KYGL
E
T
T
L
L
A
E
L
NNLTPST
Q
L
R
I
G
D
I
IKVPNL
47
Fugue
53.18
15%
60
- C1 -
-
2OCE
-
?
A:
[2-730]
D
S
I
N
T
R
I
A
E
E
L
S
A
L
P
S
G
R
V
Q
P
Q
Q
V
A
A
A
V
A
L
L
---
D
E
G
S
T
V
P
F
I
A
R
Y
R
K
E
V
T
----
G
S
L
D
D
T
Q
L
R
M
L
E
E
R
L
R
Y
--
L
R
E
L
E
E
R
R
G
A
I
L
A
S
I
E
E
Q
G
K
L
T
-------
P
E
L
A
R
D
I
K
L
A
D
T
K
T
R
L
E
D
L
Y
L
P
Y
K
Q
K
R
R
T
-----
K
G
Q
I
A
L
E
A
G
L
---
G
-
A
L
-
A
D
A
L
F
D
D
P
T
L
V
P
E
S
E
A
A
-----------------
R
F
V
D
-----
A
E
K
G
F
A
D
V
K
A
V
L
E
G
A
K
Y
I
L
M
E
R
F
A
E
D
A
-------
T
--------
L
L
D
K
L
R
V
F
M
K
N
E
A
T
L
T
A
R
V
V
P
G
K
E
Q
------
E
--
G
A
K
F
S
D
---
Y
F
---------------
E
------------------
H
-
D
E
P
L
K
S
A
P
-----------------------------------------------------------------------------------
S
H
R
A
L
A
I
F
R
G
R
N
E
G
-----------------
V
L
S
A
S
L
K
V
G
E
E
A
P
G
T
L
H
P
C
E
V
M
I
A
E
--------------------------------------------
R
F
G
L
S
N
Q
G
R
A
A
D
K
W
L
A
E
V
V
R
W
T
W
K
V
K
L
Y
T
H
L
E
T
D
L
F
G
E
L
R
D
G
A
E
D
E
A
I
S
V
F
A
R
N
L
H
D
L
L
L
A
A
P
A
G
P
R
A
T
L
G
L
D
-----------------------------------------
P
G
L
R
T
G
V
K
V
A
V
V
D
A
T
G
K
L
L
D
T
A
T
V
Y
P
H
A
P
K
N
Q
W
D
Q
T
L
A
V
L
A
A
L
C
A
K
H
Q
V
E
---
L
I
A
I
G
N
G
T
A
S
R
E
T
D
K
L
A
G
E
L
I
K
K
Y
P
G
M
K
-
L
T
K
I
M
V
S
E
A
G
A
S
V
Y
S
A
S
E
L
A
A
K
E
F
P
E
L
-
D
V
S
L
R
G
A
V
S
I
A
R
R
L
Q
---
D
P
L
A
E
L
V
K
I
---
E
P
K
S
I
G
-----
V
G
Q
Y
Q
H
D
V
S
Q
L
K
L
A
R
S
L
D
A
V
V
E
D
C
V
N
A
---------------
V
G
V
D
V
N
T
A
S
A
A
L
L
A
------
R
I
S
G
----
L
N
S
T
L
A
Q
N
I
V
A
H
R
D
A
N
G
A
F
R
T
------------
R
D
E
L
K
K
V
S
R
L
G
E
K
T
F
E
Q
A
A
G
F
L
R
V
M
N
G
--
D
N
P
L
D
---------------------
A
---------------------
S
A
V
H
--------
P
E
T
Y
P
L
-
V
Q
R
I
A
A
D
T
E
R
-
D
I
R
S
L
I
G
D
S
A
F
L
K
R
L
D
P
K
K
--
F
T
D
E
T
F
G
L
P
T
V
T
D
I
L
K
E
-
L
D
K
P
G
R
D
P
R
P
E
F
K
T
A
E
F
Q
E
G
V
E
S
L
K
D
L
K
-----------
P
G
M
V
L
E
G
V
V
T
N
V
T
-------------------------
N
F
G
A
F
V
D
I
G
V
H
Q
D
G
L
V
H
I
S
A
L
S
E
K
F
V
K
D
-
P
Y
E
V
V
K
A
G
D
I
V
K
V
K
V
M
E
-------
V
D
I
P
R
N
----
R
V
G
L
S
M
R
M
S
D
T
P
G
-------------------------
4
PsiBlast_PDB
50.45
37%
-157
- C3 -
-
4UZ3
3
?
A:
[5-96]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
V
A
P
G
D
T
L
Y
S
I
A
R
R
Y
G
-
T
T
V
E
E
L
M
R
L
N
G
L
E
-
S
F
L
-
L
Q
P
G
Q
V
L
K
L
P
S
R
E
-------
R
T
H
V
V
A
P
G
D
T
L
F
S
L
A
R
R
Y
G
T
T
V
E
A
L
M
R
L
N
G
L
S
-
S
P
E
I
K
V
G
Q
V
L
R
L
P
E
-
22
PsiBlast_CBE
49.82
37%
-150
- C3 -
-
4UZ3
3
?
B:
[5-96]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
V
A
P
G
D
T
L
Y
S
I
A
R
R
Y
G
-
T
T
V
E
E
L
M
R
L
N
G
L
E
-
S
F
L
-
L
Q
P
G
Q
V
L
K
L
P
S
R
E
-------
R
T
H
V
V
A
P
G
D
T
L
F
S
L
A
R
R
Y
G
T
T
V
E
A
L
M
R
L
N
G
L
S
-
S
P
E
I
K
V
G
Q
V
L
R
L
P
E
-
5
PsiBlast_PDB
48.13
34%
-139
- C3 -
-
4S3K
-
?
A:
[1-103]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
F
A
Q
I
Y
T
V
K
A
G
D
S
I
Y
S
I
A
K
Q
F
R
-
I
D
A
G
K
I
I
R
A
N
E
L
P
-
N
P
N
Q
L
V
I
G
Q
S
M
V
I
P
I
N
G
-------
T
Y
Y
T
V
K
A
G
D
T
I
W
K
V
G
R
K
L
G
V
S
Y
Q
A
I
A
N
A
N
N
V
S
V
T
A
P
L
T
P
G
R
R
I
L
I
P
--
38
Fugue
47.07
30%
-12
- C3 -
-
4B8V
3
?
A:
[36-224]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
S
T
-
S
N
I
K
Y
T
V
V
K
G
D
T
L
T
S
I
A
---
K
K
F
K
S
G
I
C
N
I
V
S
V
N
K
L
A
N
P
N
L
I
E
L
G
A
T
L
I
I
P
E
N
--
C
S
N
P
D
NKSCVSTPAEPTETCVPGLPG
S
---------------------
Y
T
I
V
S
G
D
T
L
T
N
I
S
Q
D
F
N
I
T
L
D
S
L
I
A
A
N
T
Q
-
I
E
N
P
D
A
I
D
V
G
Q
I
I
T
V
P
-----------
V
C
P
S
S
Q
C
E
A
V
G
-
T
Y
N
I
V
A
G
D
L
F
V
D
L
A
A
T
Y
H
T
T
I
G
Q
I
K
A
L
N
N
N
V
N
P
S
K
L
K
V
G
Q
Q
I
I
L
P
Q
D
C
K
N
V
T
------------------------------------------------------------------------------------------------------------------------------
65
HHSearch
46.96
22%
-8
- C3 -
-
4B8V
3
?
A:
[41-219]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
K
Y
T
V
V
K
G
D
T
L
T
S
I
A
K
K
F
K
S
G
I
C
N
I
V
S
V
N
K
L
A
N
P
N
L
I
E
L
G
A
T
L
I
I
P
E
N
C
S
N
P
D
N
K
S
CVS
T
P
A
E
P
T
E
T
C
V
P
G
L
P
G
S
Y
T
I
V
S
G
D
T
L
T
N
I
S
Q
D
F
N
I
T
L
D
S
L
I
A
A
N
T
Q
I
E
N
P
D
A
I
D
V
G
Q
I
I
T
V
P
V
C
P
S
S
-------------------
Q
C
E
A
V
G
T
Y
N
I
V
A
G
D
L
F
V
D
L
A
---
A
T
Y
H
T
T
I
G
Q
I
K
A
L
N
N
N
V
N
P
S
K
L
K
V
G
Q
Q
I
I
L
P
Q
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
46.60
32%
-126
- C3 -
-
5C8P
3
?
A:
[58-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
T
V
T
V
Q
Q
G
D
T
L
R
D
I
G
---
R
R
F
D
C
D
F
H
E
I
A
R
R
N
N
I
Q
N
E
D
L
I
Y
P
G
Q
V
L
Q
V
G
G
N
FW
D
S
A
R
D
---------------------
V
---------------------
R
L
V
D
G
G
K
V
L
E
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
46.48
37%
-193
- C3 -
-
4UZ3
2
?
C:
[5-48]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
V
A
P
G
D
T
L
Y
S
I
A
R
R
Y
G
-
T
T
V
E
E
L
M
R
L
N
G
L
E
-
S
F
L
-
L
Q
P
G
Q
V
L
K
L
P
S
---------------------------------------------------------
64
HHSearch
45.48
22%
-45
- C3 -
-
4B8V
3
?
A:
[41-218]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
-
K
Y
T
V
V
K
G
D
T
L
T
S
I
A
K
K
F
K
S
G
I
C
N
I
V
S
V
N
K
L
A
N
P
N
L
I
E
L
G
A
T
L
I
I
P
E
N
C
S
N
P
D
N
K
S
C
V
S
T
P
A
E
P
T
E
T
C
V
P
G
L
P
G
S
Y
T
I
V
S
G
D
T
L
T
N
I
S
Q
D
F
N
-
I
T
L
D
S
L
I
A
A
N
T
Q
I
E
N
P
D
A
I
D
V
G
Q
I
I
T
V
P
V
C
P
S
S
Q
C
E
A
V
G
T
Y
N
I
V
A
G
D
L
F
V
D
L
A
A
T
Y
H
T
T
I
G
Q
I
K
A
L
N
N
N
V
N
P
S
K
L
K
V
G
Q
Q
I
I
L
P
Q
-
36
PsiBlast_CBE
45.27
32%
-129
- C3 -
-
5C8Q
4
?
B:
[58-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
T
V
T
V
Q
Q
G
D
T
L
R
D
I
G
---
R
R
F
D
C
D
F
H
E
I
A
R
R
N
N
I
Q
N
E
D
L
I
Y
P
G
Q
V
L
Q
V
G
G
N
FW
D
S
A
R
D
---------------------
V
---------------------
R
L
V
D
G
G
K
V
L
E
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.75
27%
-17
- C3 -
-
4B8V
3
?
A:
[44-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
V
V
K
G
D
T
L
T
S
I
A
---
K
K
F
K
S
G
I
C
N
I
V
S
V
N
K
L
A
N
P
N
L
I
E
L
G
A
T
L
I
I
P
E
N
--
C
S
N
P
D
---------------------
N
KSCVSTPAEPTETCVPGLPG
S
Y
T
I
V
S
G
D
T
L
T
N
I
S
Q
D
F
N
I
-
T
L
D
S
L
I
A
A
N
T
Q
I
E
N
P
D
A
I
D
V
G
Q
I
I
T
V
P
-----------
V
C
P
S
S
Q
C
E
A
V
G
-
T
Y
N
I
V
A
G
D
L
F
V
D
L
A
A
T
Y
H
T
T
I
G
Q
I
K
A
L
N
N
N
V
N
P
S
K
L
K
V
G
Q
Q
I
I
L
P
Q
D
C
K
N
V
T
------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.44
27%
-24
- C3 -
-
4B9H
4
?
A:
[44-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
V
V
K
G
D
T
L
T
S
I
A
---
K
K
F
K
S
G
I
C
N
I
V
S
V
N
K
L
A
N
P
N
L
I
E
L
G
A
T
L
I
I
P
E
N
--
C
S
N
P
D
---------------------
N
KSC
V
S
T
P
A
E
PTETCVPGLPG
S
Y
T
I
V
S
G
D
T
L
T
N
I
S
Q
D
F
N
I
-
T
L
D
S
L
I
A
A
N
T
Q
I
E
N
P
D
A
I
D
V
G
Q
I
I
T
V
P
-----------
V
C
P
S
S
Q
C
E
A
V
G
-
T
Y
N
I
V
A
G
D
L
F
V
D
L
A
A
T
Y
H
T
T
I
G
Q
I
K
A
L
N
N
N
V
N
P
S
K
L
K
V
G
Q
Q
I
I
L
P
Q
D
C
K
N
V
T
------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
42.59
32%
-119
- C3 -
-
4S3J
1
?
B:
[7-115]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
R
S
G
D
S
V
Y
S
L
A
S
K
Y
G
S
T
P
D
E
I
V
K
D
N
G
L
N
P
A
E
T
L
V
V
G
Q
A
L
I
V
--------------
N
T
K
G
N
N
Y
Y
V
Q
P
G
D
S
L
Y
R
I
S
Q
T
Y
N
V
P
L
A
S
L
A
K
V
N
N
L
S
L
K
S
I
L
H
V
G
Q
--
Q
L
Y
V
P
K
G
T
K
R
S
V
E
---
S
I
A
Y
L
Q
P
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
42.51
32%
-111
- C3 -
-
4S3J
1
?
A:
[7-117]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
R
S
G
D
S
V
Y
S
L
A
S
K
Y
G
S
T
P
D
E
I
V
K
D
N
G
L
N
P
A
E
T
L
V
V
G
Q
A
L
I
V
--------------
N
T
K
G
N
N
Y
Y
V
Q
P
G
D
S
L
Y
R
I
S
Q
T
Y
N
V
P
L
A
S
L
A
K
V
N
N
L
S
L
K
S
I
L
H
V
G
Q
--
Q
L
Y
V
P
K
G
T
K
R
S
V
E
---
S
I
A
Y
L
Q
P
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
42.38
31%
-130
- C3 -
-
1E0G
-
A:
[1-48]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
I
T
Y
R
V
R
K
G
D
S
L
S
S
I
A
---
K
R
H
G
V
N
I
K
D
V
M
R
W
N
S
D
T
A
N
--
L
Q
P
G
D
K
L
T
L
F
V
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
42.26
25%
24
- C2 -
-
4OZ9
-
MLTF_PSEAE
A:
[253-422]
-------------------------------------------------------------------------------------------------------------------------------
Q
Q
R
L
P
R
Y
E
S
H
F
K
Q
S
G
K
Q
L
D
T
D
W
R
L
L
A
A
-
I
G
Y
Q
E
S
L
W
Q
P
G
A
T
S
K
T
G
V
R
G
L
M
M
L
T
N
R
T
A
Q
A
M
G
V
S
-----------
N
R
L
D
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
E
L
P
ESIKE
P
D
R
--------
S
W
F
A
L
A
A
Y
N
I
G
G
A
H
L
E
D
A
R
K
M
A
E
K
E
------
G
L
-
N
P
N
K
W
L
---
D
V
K
K
M
------------
L
P
R
L
AQKQWYAKTRYGYAR
G
-
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
41.87
32%
-115
- C3 -
-
4S3J
1
?
C:
[7-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
R
S
G
D
S
V
Y
S
L
A
S
K
Y
G
S
T
P
D
E
I
V
K
D
N
G
L
N
P
A
E
T
L
V
V
G
Q
A
L
I
V
--------------
N
T
K
G
N
N
Y
Y
V
Q
P
G
D
S
L
Y
R
I
S
Q
T
Y
N
V
P
L
A
S
L
A
K
V
N
N
L
S
L
K
S
I
L
H
V
G
Q
--
Q
L
Y
V
P
K
G
T
K
R
S
V
E
---
S
I
A
Y
L
Q
P
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
HHSearch
41.50
24%
26
- C2 -
-
4P0G
3
MLTF_PSEAE
A:
[261-429]
--------------------------------------------------------------------------------------------------------------------------------
Q
R
L
P
R
Y
E
S
H
F
K
Q
S
G
K
Q
L
D
T
D
W
R
L
L
A
A
-
I
G
Y
Q
E
S
L
W
Q
P
G
A
T
S
K
T
G
V
R
G
L
M
M
L
T
N
R
T
A
Q
A
M
G
V
S
-----------
N
R
L
D
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
E
L
P
ESIKE
P
D
R
--------
S
W
F
A
L
A
A
Y
N
I
G
G
A
H
L
E
D
A
R
K
M
A
E
K
E
------
G
L
-
N
P
N
K
W
L
---
D
V
K
K
M
LPRLAQKQWYAK
T
RYGYAR------------
G
-
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
40.28
22%
-16
- C2 -
-
4CFP
3
MLTC_ECOLI
B:
[166-339]
-----------------------------------------------------------------------------------------------------------------------------
H
L
D
K
R
A
H
K
Y
L
G
M
V
R
Q
A
S
R
K
Y
G
V
D
E
S
L
-
I
L
A
I
M
Q
T
Q
S
S
F
N
P
Y
A
V
S
R
S
D
A
L
G
L
M
Q
V
V
Q
H
T
A
G
K
D
V
F
R
S
Q
G
KSGTP
S
R
S
F
L
F
D
P
A
S
N
I
D
T
G
T
A
Y
L
A
M
L
N
N
V
Y
L
-------
G
GIDNPTSR
R
Y
A
V
I
T
A
Y
N
G
G
A
G
S
V
L
R
V
F
S
N
D
K
I
Q
AANIIN
T
M
T
P
G
D
V
Y
Q
TLT
T
R
---------------
H
------------------
P
S
A
E
S
R
R
Y
L
Y
K
V
N
T
A
Q
K
S
Y
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
40.23
27%
25
- C3 -
-
5JCE
4
CEBIP_ORYSJ
A:
[77-243]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
S
D
R
L
P
I
Y
V
V
Q
P
Q
D
G
L
D
A
I
A
R
NV
F
N
A
F
V
T
Y
Q
E
I
A
A
A
N
N
I
P
D
P
N
K
I
N
V
S
Q
T
L
W
I
P
L
P
--
C
S
C
D
K
---------------------
E
EG
S
N
V
M
H
L
A
------------
Y
S
V
G
K
G
E
N
T
S
A
I
A
A
K
Y
G
V
-
T
E
S
T
L
L
T
R
N
K
-
I
D
D
P
T
K
L
Q
M
G
Q
I
L
D
V
P
L
P
V
C
R
S
S
I
S
D
T
S
A
D
H
N
L
M
L
L
P
D
G
T
Y
G
F
T
A
G
N
C
I
R
C
S
C
S
S
T
T
Y
Q
L
N
C
T
A
V
Q
N
------------------------------------------------------------------------------------------------------------------------------------------------------