@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VL07: (2017-10-30 )
MNYTNNKRILTRSALVLAILGSLAGCGSDNDDTTVPSTTKPPQLSPAVGVKMTGSCSVLLGFQYNNTVISSATLQEAGTLTVANKPIGAHCLVKGYMDQRVSPVDGQTYQIGFEMRLPVDWNGRFLYQGNGGTDSNLVPATGQVGSGGPLTNALHDGFAVISSDAGHNTSQNPMFGLDPQARINYGYGAITKLTPMAKNLIKAAYGKLPDRSYAGGTSNGGRHAMIAATRLGDQYDGILASTPGFHLPRAAAAQLYTAQQLRRVATDENDLSTALTLPERKVLAKAILDRCDALDGIADGLVQDVESCRKAFDIHKDVPVCPSTRDGTCLSTEQIGVLANIYRGPVNSAGQALYATQPFDPGLVGSNWASWKFESSVGTARDPVAVGILFQVPPDPTVTQNSRQFAFNFNFDTDYPKLSATNDVYTESSMSFMMPPDELNLDKLRNHGGKMIVVQGTADGVFSVDDTQNWYDQLLQHYKNNAKGTAPEFARFFRVPGMNHTRDGIATNQFDALTALVNWVEYGQVPDKIIATARGAGNPSGQVNTELPQDWAPDRTRPLCPYPLIARYNGQGDSEKAENFSCK
Atome Classification :
(20 SA)
--------------------.........10........20........30........40........50..-----......60......-----...70........-80..----------.....-----.90.-.......100-.........110........120---.----.......130..-...-..140.......150..-.....160.......170.----.-------------....--..180.......-190.......200.........210.........220.......230.-......240.......250....--...260.......270....-...280--.........290......--...300.......310.......320....---..-..330.......340.......350..----.-....360.......370.......380......--.390------..-.....--400.......410......-.420...-....430........440.......450.......460.......470.......480.......490...---....500.---------.....--------------.510-----..-.......520---.........530.......540...----.....550.......560.......570-.......580.--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------MNYTNN
K
R
I
L
T
R
S
A
L
V
L
A
I
L
G
S
L
AGCGSDNDDTTVPSTTKPPQLSPAV
G
V
K
M
T-----G
S
C
S
V
L
L
-
G
F
QYN
N
-----
T
V
ISSATLQEA
G
T
-
L
T
VA----------NKPI
G
-----
A
H
C
L
-
V
K
G
Y
M
DQR---VSPVDG
Q
T
Y
Q
I
-
G
F
E
M
RLPVDW----N----
G
R
F
L
Y
QGNGGTD-SNL-VPATGQVGSGGP
L
T
N
A
L
-HD
G
F
A
V
ISSDAGHNTSQ-N----P-------------MFGL--DPQ
A
R
I
N
YGYG
A
-
I
T
K
L
T
P
M
A
K
N
L
--
I
K
A
A
YGKLPD--RSYAGGTSNGG
R
H
A
M
I
A
A
TRLGD-QYD
G
I
LASTPGFHL
P
R
A
A
A
A
Q
L
Y
--
T
A
Q
Q
L
R
R
V
ATDENDL
S
T
ALT-L
P
E
R
----
K
V
L
A
K
A
I
L
D
R
--
C
D
A
L
D
G
--
I
A
D
G
L
V
Q
D
V
E
S
C
R
K
A
F
D
IHKDVPVC-PSTR---DG-TCL
S
T
E
Q
I
G
V
L
A
N
I
YRGPVNSAG
Q
A
L
Y
----A-TQPFDPGLVGSNWA
S
W
K
F
ESSVGTARD
P
V
A
V
G
I
--
L
F
QV------PP-DPTVT--QNS
R
Q
F
A
F
N
FNFDTDYPKL-SATNDVY-TESS
M
S
-FMMPPDEL
N
L
D
K
L
RNHGG
K
M
I
V
V
Q
GTAD
G
V
F
SVD
D
T
Q
N
W
Y
D
Q
L
L
Q
H
Y
KNNAKGT
A
P
E
F
A
R
F
F
RV---PGMNHTRD---------GIAT
N
--------------
Q
F
-------
D
A
-
L
T
A
L
V
N
W
V
-----
E
YGQV
P
D
K
I
I
A
TARGAGNPS-GQVN----TELPQDWAPDRTRPLCPYP
L
I
A
R
YNGQG-DS
E
K
AENFSCK--
30
Fugue
87.59
26%
-20
- C4 -
-
3WMT
6
FAEB1_ASPOR
A:
[18-522]
---------------------
S
F
Q
A
E
C
E
S
F
K
A
K
I
N
V
--------------
T
N
A
N
V
H
S
V
T
Y
V
P
---
A
G
V
N
I
S
M
A
-----
D
N
P
S
I
C
G
-
G
D
P
I
T
S
-----
T
F
------------------------------------
A
F
C
R
-
I
A
L
N
V
T
T
S
---------
S
K
S
Q
I
-
F
M
E
A
W
L
P
S
N
Y
----
S
----
G
R
F
L
S
T
G
N
G
G
---------
L
G
G
C
V
-
K
Y
D
D
M
A
Y
A
A
-
G
Y
G
F
A
T
V
G
T
N
N
G
H
F
G
N
N
-
G
----
V
-------------
S
F
Y
Q
--
N
T
E
V
V
E
D
F
A
Y
R
A
-
L
H
T
G
V
V
V
G
K
E
L
--
T
K
N
F
Y
P
Q
G
Y
N
--
K
S
Y
Y
L
G
C
S
T
G
G
R
Q
G
W
K
S
V
Q
T
F
P
D
-
D
F
D
G
V
V
A
G
A
P
A
F
N
---
F
I
N
L
T
S
W
--
G
A
R
F
L
T
L
T
G
D
S
S
A
E
--
T
F
V
T
-
E
T
Q
W
----
T
A
V
H
N
E
I
I
R
Q
--
C
D
S
L
D
G
--
A
K
D
G
I
I
E
D
P
D
L
C
Q
P
I
I
E
A
L
L
C
N
A
T
Q
-
S
S
T
S
----
G
-
T
C
L
T
G
A
Q
V
K
T
V
N
G
V
F
S
A
T
Y
G
L
N
G
S
F
L
Y
----
P
R
M
Q
P
------
G
S
E
L
A
A
Y
S
S
-----------------
Y
Y
S
G
------
T
P
-
F
A
Y
A
E
--
D
W
Y
R
Y
V
V
F
N
-
N
T
N
W
D
V
A
T
W
-
T
V
Q
D
A
A
I
-
A
N
A
Q
D
P
-
Y
Q
I
S
T
W
N
G
D
L
S
P
F
Q
K
K
G
G
K
V
L
H
Y
H
G
M
E
D
A
I
I
S
S
E
S
S
K
V
Y
Y
K
H
V
A
D
T
M
N
L
S
-
P
S
E
L
D
S
F
Y
R
F
F
P
I
---
S
G
M
A
H
C
A
N
ADGPSAIGQ
G
T
G
T
F
AGNNP---------
Q
D
-------
N
V
-
L
L
A
M
V
Q
W
V
-----
E
E
G
V
A
P
D
----
F
V
R
G
A
K
L
N
G
-
S
--------------
T
V
E
Y
R
R
K
H
C
K
Y
P
K
R
N
R
Y
V
G
P
G
-
S
Y
T
D
E
N
A
W
E
C
V
--
1
PsiBlast_PDB
79.81
23%
-15
- C4 -
-
3WMT
5
FAEB1_ASPOR
A:
[85-521]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
-
F
M
E
A
W
L
P
S
N
Y
----
S
----
G
R
F
L
S
T
G
N
G
G
L
----------
G
G
C
V
K
Y
D
D
M
A
Y
A
A
-
G
Y
G
F
A
T
V
G
T
N
N
G
H
F
G
N
N
-
G
----
V
-------------
S
F
Y
Q
--
N
T
E
V
V
E
D
F
A
Y
R
A
-
L
H
T
G
V
V
V
G
K
E
L
--
T
K
N
F
Y
P
Q
G
Y
N
--
K
S
Y
Y
L
G
C
S
T
G
G
R
Q
G
W
K
S
V
Q
T
F
P
D
-
D
F
D
G
V
V
A
G
A
P
A
F
N
F
I
N
L
T
S
---
W
--
G
A
R
F
L
--
T
L
T
G
D
S
S
A
E
T
F
V
T
-
E
T
Q
W
----
T
A
V
H
N
E
I
I
R
Q
--
C
D
S
L
D
G
--
A
K
D
G
I
I
E
D
P
D
L
C
Q
P
I
I
----
E
A
L
L
C
-
N
A
T
Q
SST
S
G
-
T
C
L
T
G
A
Q
V
K
T
V
N
G
V
F
S
A
T
Y
G
L
N
G
S
F
L
Y
----
P
-
R
--
M
Q
P
G
S
E
L
A
A
Y
S
S
Y
Y
S
G
T
P
F
A
Y
A
E
D
W
Y
-----------------------------
R
Y
V
V
F
N
-
N
T
N
W
D
V
A
T
W
-
T
V
Q
D
A
A
I
-
A
N
A
Q
D
P
-
Y
Q
I
S
T
W
N
G
D
L
S
P
F
Q
K
K
G
G
K
V
L
H
Y
H
G
M
E
D
A
I
I
S
S
E
S
S
K
V
Y
Y
K
H
V
A
D
T
-
M
N
L
S
P
S
E
L
D
S
F
Y
R
F
F
P
I
---
S
G
M
A
H
C
A
N
ADGPSAI--
G
Q
G
T
G
--------------
T
F
AGNNPQD
N
V
-
L
L
A
M
V
Q
W
V
-----
E
E
G
V
A
P
D
F
V
----
R
G
A
K
L
N
G
-
S
T
V
--------------
E
Y
R
R
K
H
C
K
Y
P
K
R
N
R
Y
V
G
P
G
-
S
Y
T
D
E
N
A
W
E
C
---
10
HHSearch
78.94
24%
9
- C4 -
-
3WMT
6
FAEB1_ASPOR
A:
[18-522]
----------------------------------------------------------------------
S
F
Q
-----
A
E
C
E
S
F
K
A
K
I
N
V
T
N
-----
A
N
V
H
S
V
T
Y
V
P
A
G
V
N
I
S
M
A
DNPSICGGDP
I
T
S
T
F
-----
A
F
C
R
-
I
A
L
N
V
T
T
S
-------
S
--
K
S
Q
I
-
F
M
E
A
W
L
P
S
N
Y
----
S
----
G
R
F
L
S
T
G
N
G
G
L
G
-
G
C
V
-
K
-
Y
D
-------
D
M
A
Y
A
A
-
G
Y
G
F
A
T
V
G
T
N
N
G
H
F
G
N
N
G
V
----
S
-------------
F
Y
-
Q
--
N
T
E
V
V
E
D
F
A
Y
R
A
-
L
H
T
G
V
V
V
G
K
E
L
--
T
K
N
F
Y
P
Q
G
Y
N
--
K
S
Y
Y
L
G
C
S
T
G
G
R
Q
G
W
K
S
V
Q
T
F
P
D
-
D
F
D
G
V
V
A
G
A
P
A
F
N
F
I
N
L
T
---
S
W
--
G
A
R
F
L
T
L
T
G
D
---
S
S
A
E
T
F
V
T
E
T
Q
W
----
T
A
V
H
N
E
I
I
R
Q
--
C
D
S
L
D
G
--
A
K
D
G
I
I
E
D
P
D
L
C
Q
--
P
I
I
E
--
A
L
L
C
-
N
A
T
Q
SST
S
G
-
T
C
L
T
G
A
Q
V
K
T
V
N
G
V
F
S
A
T
Y
G
L
N
G
S
F
L
Y
----
P
-
R
M
Q
P
G
S
E
L
A
--
A
Y
S
S
Y
Y
-------
S
G
T
P
F
A
Y
A
E
--
D
---------------------
W
Y
R
Y
V
V
F
N
N
T
N
W
D
V
A
T
W
T
V
Q
D
-
A
A
I
A
N
A
--
Q
D
P
Y
Q
I
S
T
W
N
G
D
L
S
P
F
Q
K
K
G
G
K
V
L
H
Y
H
G
M
E
D
A
I
I
S
S
E
S
S
K
V
Y
Y
K
H
V
A
D
T
M
N
L
-
S
P
S
E
L
D
S
F
Y
R
F
F
P
I
---
S
G
M
A
H
C
A
N
---------
A
D
G
P
S
AIGQGTGTFAGNNP
Q
D
-------
N
V
-
L
L
A
M
V
Q
W
V
-----
E
E
G
V
A
P
D
F
V
R
G
A
K
L
N
G
-------------------
S
T
V
E
Y
R
R
K
H
C
K
Y
P
K
R
N
R
Y
V
G
P
G
-
S
Y
T
D
E
N
A
W
E
C
V
--
31
Fugue
46.09
18%
52
- C3 -
-
2BVL
6
TOXB_CLODI
A:
[1-543]
------------MSLVN
R
K
Q
L
E
K
M
A
N
V
R
F
R
T
Q
E
D
E
Y
V
A
I
L
D
A
L
E
E
Y
H
N
M
S
E
N
T
V
V
E
K
Y
L
K
L
K
D
I
N
S
L
T
D
I
C
I
D
T
Y
KKS
G
R
N
K
A
L
K
-
K
F
K
-
E
Y
-----
L
V
T
E
V
L
E
L
K
N
N
N
L
-
T
P
V
E
----------
K
---
N
-----
L
H
F
V
W
I
G
G
Q
I
N
---------
D
T
A
I
N
Y
I
-
N
Q
W
K
D
V
N
S
D
Y
----
N
----
V
N
V
F
Y
------
D
-
S
N
------------
A
F
L
I
N
T
L
-
K
K
T
V
V
E
S
A
I
N
D
T
L
E
S
F
R
-
E
----
N
-------------
L
N
----
D
P
R
F
D
Y
N
K
F
F
R
K
R
M
E
I
I
Y
D
K
Q
K
N
F
--
I
N
Y
Y
K
A
Q
R
E
E
---------
N
P
E
L
I
I
D
D
I
V
K
T
Y
L
S
N
-
E
Y
S
K
E
I
D
E
L
N
T
Y
I
E
E
S
L
N
K
I
T
Q
N
--
S
G
N
D
V
R
N
F
G
E
F
K
N
G
E
S
F
N
L
Y
-
E
Q
E
L
VERW
N
L
A
A
A
S
D
I
L
R
--
I
S
A
L
K
E
--
I
-
G
G
M
Y
L
D
V
D
M
---
L
P
G
I
Q
P
D
L
F
E
S
-
I
E
K
P
---
S
S
-
V
T
V
D
F
W
E
M
T
K
L
E
A
I
M
K
Y
K
E
Y
I
P
E
---
Y
----
T
-
S
E
H
F
D
M
L
---
D
E
E
V
Q
S
S
F
E
S
V
L
A
S
K
S
D
K
S
E
I
-----
F
S
S
------
L
G
-
D
M
E
A
S
--
P
L
E
V
K
I
A
F
N
S
K
G
I
I
N
Q
G
L
I
-
S
V
K
D
------
S
Y
C
S
-
N
L
I
V
K
Q
I
E
N
R
Y
K
I
L
N
N
S
L
N
P
A
I
S
E
D
N
D
----
F
N
T
T
T
N
T
F
I
D
S
I
M
A
E
A
N
A
D
N
G
R
F
M
M
E
L
G
K
Y
L
R
V
GFF
P
D
V
K
T
T
I
N
---------
L
S
G
P
E
--------------
A
Y
-------
A
A
A
Y
Q
D
L
L
M
F
K
-----
E
G
S
M
N
I
H
L
I
E
A
D
L
R
N
F
E
I
S
K
-
T
N
I
S
QST
E
Q
E
M
A
S
L
W
S
F
D
----------
D
A
R
A
K
A
Q
F
-
E
E
Y
K
R
N
Y
F
E
G
A
L-
38
Fugue
45.23
18%
-32
- C1 -
-
4PG7
4
?
A:
[20-446]
------------------------------
H
M
K
K
L
N
I
A
L
L
G
-------------------------------------------
L
-
G
-
T
V
G
S
-----
G
V
V
K
I
I
E
E
N
R
Q
Q
I
-
Q
D
T
L
----------
N
K
D
I
V
-----
I
K
H
I
-
L
V
R
D
K
S
K
K
---
R
P
L
N
I
S
Q
Y
H
L
T
-
E
D
V
N
E
I
L
N
D
D
----
S
----
L
D
I
I
V
E
V
M
G
G
I
E
-
P
-----------
T
V
D
W
L
R
T
A
L
-
K
N
K
K
H
V
I
T
A
N
------------------------------------------------------
K
D
L
--
L
A
V
H
L
K
L
L
E
D
--
L
A
E
E
N
G
V
A
L
K
F
E
A
S
V
A
G
G
P
N
N
I
S
-
K
F
M
G
I
L
N
G
T
S
N
F
I
L
S
K
M
T
K
E
Q
T
------------------
T
F
E
E
A
-
L
D
E
A
----
K
R
L
G
F
A
E
A
D
P
--
T
D
D
V
E
G
---
V
D
A
A
R
K
V
V
I
T
S
Y
L
S
F
N
Q
V
I
K
L
N
D
V
---
K
R
---
R
G
I
S
G
V
T
L
T
D
I
N
V
A
D
Q
L
-
G
Y
K
I
K
L
I
G
K
G
I
Y
E
NG
K
V
-
N
A
S
V
E
P
T
L
I
D
K
K
H
-------
Q
L
A
A
V
E
D
E
Y
N
A
I
Y
--
V
I
G
D
------
A
V
-
G
D
T
M
F
Y
G
K
G
A
G
S
L
A
T
G
S
A
V
V
S
D
L
L
N
V
-
A
L
----
F
-
F
E
S
T
L
P
----
P
H
F
E
L
K
T
D
K
T
R
E
M
E
K
S
N
F
F
V
V
V
N
-----------------------
H
V
K
G
S
I
E
N
F
E
N
E
L
K
A
---
I
L
P
F
H
R
S
L
---------
R
V
A
N
Y
--------------
D
N
-------
Q
S
-
Y
A
A
V
I
V
G
L
-----
E
S
S
--
P
E
E
L
I
T
K
H
G
--------------------------------
Y
E
V
D
K
V
Y
P
V
E
G
-
V
------------
34
Fugue
44.15
15%
33
- C3 -
-
4KYI
5
?
A:
[4-544]
-------------------------
G
S
E
I
S
K
----------------
T
E
A
G
Q
Y
S
V
S
A
P
E
H
K
G
L
V
L
S
G
G
G
A
K
G
I
-----
S
Y
L
G
M
I
Q
-
A
L
Q
E
R
G
KIKNL
T
H
V
S
G
A
S
---
A
G
A
-
M
T
A
S
----------
I
L
A
V
G
MD
I
K
D
I
K
K
L
-
I
E
G
L
D
I
T
K
---
L
L
D
N
S
G
V
G
F
R
A
R
G
D
R
F
R
N
I
L
D
V
----
I
----
Y
M
M
Q
M
K
K
H
L
E
S
V
-
Q
Q
-------------
P
I
P
P
E
Q
-
Q
M
N
Y
G
I
L
K
Q
K
I
A
L
Y
E
D
K
-
L
----
S
-------------
R
A
G
I
------
V
I
N
-
N
V
D
D
-
I
I
N
L
T
K
S
V
K
D
L
E
K
L
D
K
A
L
N
S
I
P
T
E
L
K
G
A
K
G
E
Q
L
E
N
P
R
L
T
L
G
D
L
G
R
L
R
E
-
L
L
-----
P
E
E
N
K
H
L
I
K
N
L
S
V
V
V
T
NQ
T
K
H
E
L
E
R
Y
S
E
D
T
T
P
Q
Q
S
I
A
Q
-
V
V
Q
W
----
S
G
A
H
P
V
L
F
V
P
--
G
R
N
A
K
G
E
Y
I
A
D
G
G
I
L
D
-----
N
M
P
E
I
E
G
------
L
D
R
E
---
E
V
-
L
C
V
K
A
E
A
----
G
T
A
F
E
D
R
V
N
K
A
K
Q
S
A
M
----
E
-
A
I
S
W
F
K
A
R
M
D
S
------
L
V
T
S
S
V
L
N
R
E
K
V
Y
Y
N
I
D
N
M
I
Y
I
N
TGEVT
T
T
-
N
T
S
P
T
--
P
E
Q
R
A
R
A
V
K
N
G
Y
D
Q
T
M
Q
L
L
-
D
S
H
K
Q
T
F
-
D
H
P
L
M
A
-
I
L
Y
I
G
H
D
K
L
K
D
A
L
I
D
E
K
S
E
K
E
I
F
E
A
S
A
H
A
Q
A
I
L
H
L
Q
E
Q
I
V
K
E
M
N
D
G
D
Y
S
S
V
Q
N
Y
L
D
Q
I
E
D
I
L
T
V
---
D
A
--
K
M
D
D
---------
I
Q
K
E
K
--------------
A
F
-------
A
L
-
C
I
K
Q
V
N
F
L
-----
S
E
G
K
L
E
T
Y
L
N
K
V
E
A
E
A
K
A
A
A
------------
E
P
S
W
A
T
K
I
L
N
L
L
W
A
P
I
E
W
V
V
S
L
F
K
G
-
P
A
Q
D
F
K
-------
11
HHSearch
40.41
18%
3
- C4 -
-
2BKL
1
?
B:
[429-563]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
-
P
M
F
V
V
H
R
K
D
L
----
K
RDGN
A
P
T
L
L
Y
G
Y
G
G
F
N
-
V
N
M
-
E
A
N
F
R
-----
S
S
I
L
P
W
L
-
D
A
G
G
V
Y
A
V
A
N
L
R
G
G
G
E
Y
G
K
----
A
-------------
W
H
-----
D
A
G
R
L
D
K
K
Q
N
V
-
F
D
D
F
H
A
A
A
E
Y
L
--
V
Q
Q
K
Y
T
-
Q
P
K
--
R
L
A
I
Y
G
G
S
N
G
G
L
L
V
G
A
A
M
T
Q
R
P
E
-
L
Y
G
A
V
V
C
A
V
P
L
L
D
M
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
38.68
11%
65
- C3 -
-
1ZRO
-
?
A:
[8-601]
NEVLSNCRE
K
R
K
G
MKWDCKK
K
N
D
R
S
N
Y
V
C
I
P
D
R
R
I
Q
L
C
I
V
N
L
A
I
I
K
T
Y
T
K
E
T
M
K
D
H
F
I
E
A
S
K
K
E
S
Q
L
L
L
K
K
N
D
-----
N
K
Y
N
S
K
F
-
C
N
D
L
K
N
-----
S
F
L
D
Y
G
H
L
A
M
G
N
D
-
M
D
F
G
----------
G
Y
S
T
K
-----
A
E
N
K
-
I
Q
E
V
F
K
G
A
HGE
I
S
E
H
K
I
K
N
F
R
K
-
K
W
W
N
E
F
R
E
K
L
----
W
----
E
A
M
L
S
E
H
K
N
N
I
C
-
K
N
I
-
P
Q
E
E
L
Q
I
T
Q
---
W
I
K
E
W
-
H
G
E
F
L
L
E
R
D
N
R
A
K
L
P
K
S
-
K
C
KNN
A
-------------
L
Y
E
A
CE
K
E
C
I
D
P
C
M
K
Y
R
D
-
W
I
I
R
S
K
F
E
W
H
T
--
L
S
K
E
Y
E
T
Q
K
V
--
P
K
-----
E
N
A
E
N
Y
L
I
K
I
S
E
N
K
N
D
A
K
V
S
L
L
L
N
N
C
D
A
E
Y
S
K
Y
C
D
C
K
H
----
T
T
T
L
V
K
S
V
L
N
G
N
D
N
T
----
I
-
K
E
K
R
----
E
H
I
D
L
D
D
F
S
K
F
G
C
D
K
N
S
V
--
D
T
N
---
T
K
V
W
E
C
K
K
P
Y
K
L
S
T
K
-
D
V
C
V
P
P
R
R
---
Q
E
-
L
C
L
-----
G
N
I
D
R
I
Y
D
K
N
L
L
M
I
K
E
H
I
L
----
A
-
I
A
I
Y
E
S
R
I
L
K
R
K
Y
K
N
-
K
D
D
K
E
V
C
K
I
I
N
K
T
F
A
D
I
--
R
D
I
I
------
G
G
T
D
Y
W
N
D
--
L
S
N
R
K
L
V
G
K
I
N
T
N
S
N
Y
V
H
R
-
N
K
Q
N
D
K
L
-
F
R
D
E
W
W
-
K
V
I
K
K
D
V
W
N
V
I
S
W
V
F
K
D
K
T
V
----
C
K
E
D
D
I
E
N
I
P
Q
F
F
R
W
F
S
E
W
G
D
D
Y
C
Q
D
K
T
K
M
I
E
T
L
K
V
E
C
C
E
---
D
D
-------------------
N
--------------
C
K
-------
R
K
-
C
N
S
Y
K
E
W
I
S
K
K
K
E
E
Y
N
K
Q
A
K
Q
Y
Q
E
Y
Q
K
G
N
N
Y
K
M
Y
S
E
F
K
----
S
I
K
P
E
V
Y
L
K
K
Y
S
E
K
C
S
N
L
N
F
E
D
E
F
K
E
E
L
H
S
D
Y
K
N
K
C
T
M
C
P
EV
29
HHSearch
37.16
17%
9
- C4 -
-
3MUO
3
?
A:
[437-571]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
-
P
L
I
I
S
Y
R
K
G
L
KLDG
S
----
N
P
T
I
L
Y
G
Y
G
G
F
D
-
V
S
L
-
T
P
S
F
S
-----
V
S
V
A
N
W
L
-
D
L
G
G
V
Y
A
V
A
N
L
R
G
G
G
E
Y
G
Q
----
A
-------------
W
H
-----
L
A
G
T
Q
Q
N
K
Q
N
V
-
F
D
D
F
I
A
A
A
E
Y
L
--
K
A
E
G
Y
T
-
R
T
D
--
R
L
A
I
R
G
G
S
N
G
G
L
L
V
G
A
V
M
T
Q
R
P
D
-
L
M
R
V
A
L
P
A
V
G
V
L
D
M
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
36.46
16%
-2
- C4 -
-
5UW3
-
?
B:
[483-620]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-
P
I
F
I
A
A
R
K
G
I
SLDG
S
----
H
P
C
E
M
H
G
Y
G
G
F
G
-
I
N
M
-
M
P
T
F
S
----
A
S
R
I
V
F
L
K
-
H
L
G
G
V
F
C
L
A
N
I
R
G
G
G
E
Y
G
E
----
E
-------------
W
H
-----
K
A
G
F
R
D
K
K
Q
N
V
-
F
D
D
F
I
S
A
A
E
Y
L
--
I
S
S
G
Y
T
-
K
A
R
--
R
V
A
I
E
G
G
S
N
G
G
L
L
V
A
A
C
I
N
Q
R
P
D
-
L
F
G
C
A
E
A
N
C
G
V
M
D
M
L
R
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
36.29
25%
-84
- C4 -
-
1FJ2
-
LYPA1_HUMAN
B:
[109-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
P
S
N
--
R
I
I
L
G
G
F
S
Q
G
G
A
L
S
L
Y
T
A
L
T
T
Q
Q
-
K
L
A
G
V
T
A
L
S
C
W
L
P
L
R
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
36.21
28%
-67
- C4 -
-
3FCX
-
ESTD_HUMAN
B:
[123-179]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
V
T
E
E
L
P
Q
L
--
I
N
A
N
F
P
V
D
P
Q
--
R
M
S
I
F
G
H
S
M
G
G
H
G
A
L
I
C
A
L
K
N
P
G
-
K
Y
K
S
V
S
A
F
A
P
I
C
N
P
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
36.06
16%
-5
- C4 -
-
1Z68
1
SEPR_HUMAN
B:
[479-618]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
-
W
Y
K
M
I
L
P
P
Q
F
----
D
RSKK
Y
P
L
L
I
Q
V
Y
G
G
P
C
-
S
Q
S
-
V
R
S
-
V
F
A
--
V
N
W
I
S
Y
L
A
S
K
E
G
M
V
I
A
L
V
D
G
R
G
T
A
F
Q
-
G
----
D
-------------
K
L
----
L
Y
A
V
Y
R
K
L
G
V
Y
E
-
V
E
D
Q
I
T
A
V
R
K
F
--
I
E
M
G
F
-
I
D
E
K
--
R
I
A
I
W
G
W
S
Y
G
G
Y
V
S
S
L
A
L
A
S
G
T
G
-
L
F
K
C
G
I
A
V
A
P
V
S
S
W
E
Y
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
35.80
14%
-14
- C4 -
-
3O4H
2
APEH_AERPE
A:
[346-477]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
P
T
Y
V
L
E
S
G
R
A
PT--
P
----
G
P
T
V
V
L
V
H
G
G
P
F
-
A
E
D
-
S
D
S
W
D
-----
T
F
A
A
S
L
A
-
A
A
G
F
H
V
V
M
P
N
Y
R
G
S
T
G
Y
-
G
E
---
E
-------------
W
-----
R
L
K
I
I
G
D
P
C
G
G
E
-
L
E
D
V
S
A
A
A
R
W
A
--
R
E
S
G
---
L
A
S
--
E
L
Y
I
M
G
Y
S
Y
G
G
Y
M
T
L
C
A
L
T
M
K
P
G
-
L
F
K
A
G
V
A
G
A
S
V
V
D
W
E
E
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
35.14
16%
22
* C4 *
-
2Z3Z
1
PTP_PORGI
A:
[468-608]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
-
Y
Y
K
L
T
M
P
L
H
F
DPA
K
K
----
Y
P
V
I
V
Y
V
Y
G
G
P
H
A
Q
L
V
T
K
T
W
------
G
G
W
D
I
Y
M
A
-
Q
K
G
Y
A
V
F
T
V
D
S
R
G
S
A
N
R
-
G
----
A
-------------
A
--
F
--
E
Q
V
I
H
R
R
L
G
Q
T
E
-
M
A
D
Q
M
C
G
V
D
F
L
--
K
S
Q
-
S
W
V
D
A
D
--
R
I
G
V
H
G
W
S
Y
G
G
F
M
T
T
N
L
M
L
T
H
G
D
-
V
F
K
V
G
V
A
G
G
P
V
I
D
W
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
35.12
13%
-118
- C3 -
-
3BD1
2
?
A:
[1-65]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
A
I
D
I
A
---
I
N
K
L
G
S
V
S
---------
A
L
A
A
S
--------------
L
G
-------
V
R
-
Q
S
A
I
S
N
W
R
-----
A
R
G
R
V
P
A
E
R
C
I
D
I
E
R
V
T
N
G
A
-
V
I
C
R
----
E
L
R
P
D
V
F
G
A
---------------------------------
13
HHSearch
35.05
18%
3
- C4 -
-
3E4D
-
?
A:
[27-179]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
M
-
T
F
A
V
Y
V
P
P
K
A
IH
E
-
P
----
C
P
V
V
W
Y
L
S
G
L
T
C
-
T
H
A
--
N
V
M
E
K
---
G
E
Y
R
R
M
A
S
-
E
L
G
L
V
V
V
C
P
D
T
S
P
R
G
N
D
-
V
----
P
DELTNWQMGKGAG
F
Y
L
D
--
A
T
E
E
P
W
S
E
H
Y
Q
M
-
Y
S
Y
V
T
E
E
L
P
A
L
--
I
G
Q
H
F
R
A
D
M
S
--
R
Q
S
I
F
G
H
S
M
G
G
H
G
A
M
T
I
A
L
K
N
P
E
-
R
F
K
S
C
S
A
F
A
P
I
V
A
P
S
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
34.83
16%
-3
- C4 -
-
5UW3
-
?
A:
[483-620]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-
P
I
F
I
A
A
R
K
G
I
SLDG
S
----
H
P
C
E
M
H
G
Y
G
G
F
G
-
I
N
M
-
M
P
T
F
S
----
A
S
R
I
V
F
L
K
-
H
L
G
G
V
F
C
L
A
N
I
R
G
G
G
E
Y
G
E
----
E
-------------
W
H
-----
K
A
G
F
R
D
K
K
Q
N
V
-
F
D
D
F
I
S
A
A
E
Y
L
--
I
S
S
G
Y
T
-
K
A
R
--
R
V
A
I
E
G
G
S
N
G
G
L
L
V
A
A
C
I
N
Q
R
P
D
-
L
F
G
C
A
E
A
N
C
G
V
M
D
M
L
R
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
33.93
21%
-49
- C4 -
-
3LS2
-
?
A:
[125-177]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
L
P
A
L
--
I
E
Q
H
F
P
-
V
T
S
--
T
K
A
I
S
G
H
S
M
G
G
H
G
A
L
M
I
A
L
K
N
P
Q
-
D
Y
V
S
A
S
A
F
S
P
I
V
N
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
33.62
11%
-24
- C4 -
-
2HDW
-
Y2218_PSEAE
A:
[80-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
-
A
A
D
L
Y
L
P
K
N
R
GG
D
-
R
----
L
P
A
I
V
I
G
G
P
-
F
G
-
A
V
K
-
E
Q
S
S
G
-----
L
Y
A
Q
T
M
A
-
E
R
G
F
V
T
L
A
F
D
P
S
Y
T
G
E
S
-
G
----
G
-------------
Q
P
-
R
--
N
V
---
A
-
S
P
D
I
N
-
T
E
D
F
S
A
A
V
D
F
I
--
S
L
L
-
P
E
V
N
R
E
--
R
I
G
V
I
G
I
C
G
W
G
G
M
A
L
N
A
V
A
V
D
K
--
R
V
K
A
V
V
T
S
T
M
Y
D
M
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------