@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLP8: (2017-11-03 )
MLKQLKEDIQAVFARDPAARNTLEVLTTYPGIHALLLHRLAHELWKKDCKGTARFVSSFSRFATGIEIHPGAKIGKRFFIDHGMGVVIGETAEIGDDVTLYHGVTLGGTTWNKGKRHPTLEDGVVVGAGAKILGPFTVGKGAKVGSNAVVTKAVPAGVTAVGNPARYIYKDADKTKDKDEERRRDYAQSIGFAPYATTADQSDPILEGMRVLLDRVQHNETRMNNLCQRLSELDPTFKKESQDEQPFSDEELKILEEIRRECGAQNKTSKT
Atome Classification :
(27 SA)
-------------------------------------------------------------------------------------------------------------------.........10........20........30........40........50........60........70........80........90........100.......110.--------......120.......130.......140.......150.......160........170...-.....180.......190.......200.......210.......220.......230.......240.......250.......260.......270
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------M
L
K
Q
L
K
E
D
I
Q
A
V
FARDPAAR
N
T
L
E
V
L
TTYP
G
I
H
A
L
L
L
H
R
L
A
H
E
L
W
K
K
DC
K
G
T
A
R
F
V
S
S
F
S
R
FAT
G
I
E
IHPGAKIG
K
R
F
F
IDHGM
G
V
V
IGETAEIGD
D
V
T
L
Y
H
G
V
T
LGGTTWNK--------GKRHPTLED
G
V
V
VGAG
A
K
I
L
G
P
F
TVGKGAKVGSN
A
V
V
TKAVPAGVTAV-GNPA
R
Y
I
YK-DADK-TK
D
K
D
E
E
R
R
R
D
Y
A
Q
SIGFAPYATTADQS
D
P
I
L
E
G
M
R
V
L
L
D
R
VQH
N
E
T
R
M
N
N
L
C
Q
R
L
S
ELDPTFKKESQDEQPF
S
D
E
E
L
K
I
L
E
E
I
R
R
E
CGAQNKTSKT
156
Fugue
82.55
48%
2
- C2 -
-
3F1X
-
?
A:
[2-300]
TTFNY
T
N
I
L
T
Q
A
V
D
E
L
S
E
SQSYKGLFHQHKDGDPLPS
A
K
S
L
Y
K
I
V
E
L
A
R
A
I
I
F
PGYFGNSTVNSHT
I
N
Y
H
I
G
V
N
V
E
T
L
F
G
L
L
T
E
Q
I
L
A
G
L
C
F
GDNEPC
R
E
T
A
S
L
L
A
A
R
F
I
S
K
L
P
E
L
R
R
I
L
A
T
D
V
E
A
A
Y
Y
G
D
P
A
A
T
C
F
G
E
I
I
S
C
Y
P
A
I
R
A
I
S
N
Y
R
I
A
H
E
L
L
I
L
G
V
P
L
I
P
R
F
I
T
E
M
A
H
S
E
T
G
I
D
I
H
P
G
A
Q
I
G
H
H
F
T
I
D
H
G
T
G
V
V
I
G
A
T
S
I
I
G
N
N
V
K
L
Y
Q
G
V
T
L
G
A
-------------
K
P
R
H
P
I
L
E
D
D
V
I
V
Y
S
N
A
T
I
L
G
R
V
T
I
G
K
G
A
T
V
G
G
N
I
W
V
T
E
N
V
P
A
G
S
R
I
V
-
Q
R
K
N
K
-----------------------------------------------------------------------------------------------------------
155
Fugue
82.25
44%
-4
- C2 -
-
1SSQ
1
CYSE_HAEIN
A:
[1-241]
-------------------------------------------MN
L
D
V
W
Q
H
I
R
Q
E
A
K
E
L
A
E
N
E
PML
A
S
F
F
H
S
T
ILKHQN
L
G
G
A
L
S
Y
L
L
A
N
K
L
ANPIMP
A
I
S
L
R
E
I
I
E
E
A
Y
Q
S
NP
S
I
I
D
C
A
A
C
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
S
--------------------------------------------------------------------------------------------------------
134
HHSearch
76.73
45%
-112
- C2 -
-
1SSQ
1
CYSE_HAEIN
A:
[75-241]
---------------------------------------------------------------------------------------------------------------------
D
C
A
A
C
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
S
--------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
75.90
46%
-118
- C2 -
-
1S80
-
CYSE_HAEIN
A:
[80-240]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
---------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
75.80
46%
-121
- C2 -
-
1SSM
-
CYSE_HAEIN
A:
[80-240]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
---------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.50
46%
-117
- C2 -
-
4HZD
1
?
A:
[91-254]
-----------------------------------------------------------------------------------------------------------------------
L
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
-
G
V
P
A
R
I
I
---------------------------------------------------------------------------------------------------------
143
HHSearch
75.36
46%
-111
- C2 -
-
4HZD
1
?
A:
[92-258]
------------------------------------------------------------------------------------------------------------------------
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
-
G
V
P
A
R
I
I
G
E
-
T
G
----------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.94
46%
-115
- C2 -
-
4HZC
-
?
A:
[91-254]
-----------------------------------------------------------------------------------------------------------------------
L
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
-
G
V
P
A
R
I
I
---------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
74.89
46%
-113
- C2 -
-
1SSQ
1
CYSE_HAEIN
A:
[80-241]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
S
--------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
74.58
46%
-117
- C2 -
-
1SST
2
CYSE_HAEIN
C:
[80-240]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
------------
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
---------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
74.06
46%
-115
- C2 -
-
1SSQ
1
CYSE_HAEIN
D:
[80-243]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
G
K
E
S
--------
G
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
S
Q
-
D
-----------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
73.60
46%
-115
- C2 -
-
4HZD
1
?
B:
[91-254]
-----------------------------------------------------------------------------------------------------------------------
L
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
-
G
V
P
A
R
I
I
---------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
73.52
46%
-127
- C2 -
-
1SST
2
CYSE_HAEIN
A:
[80-240]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
---------------
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
---------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
73.47
46%
-123
- C2 -
-
1SST
2
CYSE_HAEIN
B:
[80-240]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
H
R
D
P
A
V
E
L
W
S
T
P
L
L
Y
L
K
G
F
H
A
I
Q
S
Y
R
I
T
H
Y
L
W
N
Q
N
R
K
S
L
A
L
Y
L
Q
N
Q
I
S
V
A
F
D
V
D
I
H
P
A
A
K
I
G
H
G
I
M
F
D
H
A
T
G
I
V
V
G
E
T
S
V
I
E
N
D
V
S
I
L
Q
G
V
T
L
G
G
T
-------------
D
R
H
P
K
V
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
K
Y
A
K
I
G
A
N
S
V
V
L
N
P
V
P
E
Y
A
T
A
A
-
G
V
P
A
R
I
V
---------------------------------------------------------------------------------------------------------
135
HHSearch
73.33
44%
-114
- C2 -
-
4H7O
4
?
C:
[80-248]
----------------------------------------------------------------------------------------------------------------------
A
A
A
C
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
-
G
V
P
A
R
I
V
G
R
-
P
Q
----------------------------------------------------------------------------------------------------
144
HHSearch
72.82
46%
-135
- C2 -
-
3F1X
-
?
A:
[128-300]
---------------------------------------------------------------------------------------------------------------------
R
I
L
A
T
D
V
E
A
A
Y
Y
G
D
P
A
A
T
C
F
G
E
I
I
S
C
Y
P
A
I
R
A
I
S
N
Y
R
I
A
H
E
L
L
I
L
G
V
P
L
I
P
R
F
I
T
E
M
A
H
S
E
T
G
I
D
I
H
P
G
A
Q
I
G
H
H
F
T
I
D
H
G
T
G
V
V
I
G
A
T
S
I
I
G
N
N
V
K
L
Y
Q
G
V
T
L
G
A
K
-------------
P
R
H
P
I
L
E
D
D
V
I
V
Y
S
N
A
T
I
L
G
R
V
T
I
G
K
G
A
T
V
G
G
N
I
W
V
T
E
N
V
P
A
G
S
R
I
V
-
Q
R
K
N
K
-----------------------------------------------------------------------------------------------------------
142
HHSearch
72.66
46%
-108
- C2 -
-
4HZD
1
?
B:
[92-258]
------------------------------------------------------------------------------------------------------------------------
R
V
D
I
Q
A
V
Y
D
R
D
P
A
Y
S
R
F
M
D
P
V
L
Y
L
K
G
F
H
A
I
Q
T
H
R
L
A
H
W
L
Y
K
Q
G
R
K
D
F
A
Y
Y
L
Q
S
R
S
S
S
I
F
Q
T
D
I
H
P
A
A
R
L
G
S
G
L
F
L
D
H
A
T
G
L
V
V
G
E
T
A
V
V
E
D
N
V
S
I
L
H
G
V
T
L
G
G
T
G
K
S
S
--------
G
D
R
H
P
K
I
R
Q
G
V
L
I
G
A
G
A
K
I
L
G
N
I
Q
V
G
Q
C
S
K
I
A
A
G
S
V
V
L
K
S
V
P
H
N
V
T
V
A
-
G
V
P
A
R
I
I
G
E
-
T
G
----------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
72.57
45%
-135
- C2 -
-
4N6B
1
?
B:
[95-255]
--------------------------------------------------------------------------------------------------------------------------
D
L
R
A
A
R
E
R
D
P
A
C
V
S
Y
S
H
C
L
L
N
Y
K
G
F
L
A
C
Q
A
H
R
V
A
H
L
L
W
R
Q
S
R
R
P
L
A
L
A
L
H
S
R
I
A
N
V
F
A
V
D
I
H
P
A
A
R
I
G
K
G
I
L
F
D
H
A
T
G
V
V
V
G
E
T
A
V
I
G
N
N
V
S
I
L
H
H
V
T
L
G
G
T
------------
G
D
R
H
P
K
I
G
D
G
V
L
I
G
A
G
A
T
I
L
G
N
I
K
I
G
E
G
A
K
V
G
A
G
S
V
V
L
I
D
V
P
P
R
T
T
A
V
-
G
N
P
A
R
L
V
---------------------------------------------------------------------------------------------------------
136
HHSearch
72.37
45%
-116
- C2 -
-
3GVD
-
?
I:
[82-251]
---------------------------------------------------------------------------------------------------------------------
V
S
A
A
R
D
I
L
A
V
R
L
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
A
Q
D
R
K
A
L
A
I
Y
L
Q
N
Q
V
S
V
A
F
G
V
D
I
H
P
A
A
T
I
G
C
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
T
S
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
S
V
P
A
H
T
T
A
A
-
G
V
P
A
R
I
V
G
K
-
P
E
----------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
71.65
44%
-83
* C2 *
-
4H7O
3
?
A:
[84-259]
--------------------------------------------------------------------------------------------------------------------------
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
-
G
V
P
A
R
I
V
G
R
P
Q
S
D
K
P
S
L
D
M
D
Q
Q
------------------------------------------------------------------------------------------
13
PsiBlast_PDB
71.52
45%
-121
- C2 -
-
1T3D
1
CYSE_ECOLI
A:
[100-260]
--------------------------------------------------------------------------------------------------------------------------
D
I
Q
A
V
R
T
R
D
P
A
V
D
K
Y
S
T
P
L
L
Y
L
K
G
F
H
A
L
Q
A
Y
R
I
G
H
W
L
W
N
Q
G
R
R
A
L
A
I
F
L
Q
N
Q
V
S
V
T
F
Q
V
D
I
H
P
A
A
K
I
G
R
G
I
M
L
D
H
A
T
G
I
V
V
G
E
T
A
V
I
E
N
D
V
S
I
L
Q
S
V
T
L
G
G
T
G
K
S
G
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
R
G
A
K
I
G
A
G
S
V
V
L
Q
P
V
P
P
H
T
T
A
A
-
G
V
P
A
R
I
V
---------------------------------------------------------------------------------------------------------
141
HHSearch
71.31
39%
-125
- C2 -
-
3P47
1
?
A:
[102-270]
--------------------------------------------------------------------------------------------------------------------
K
R
T
L
K
T
D
L
I
A
A
Y
A
G
D
P
A
A
P
G
L
S
L
I
I
R
C
Y
P
G
F
Q
A
V
I
V
Y
R
I
A
H
V
L
Y
E
C
G
E
R
Y
Y
C
R
E
M
M
E
S
V
H
S
Y
T
S
I
D
I
H
P
G
A
S
I
K
G
H
F
F
I
D
H
G
V
G
V
V
I
G
E
T
A
I
I
G
E
W
C
R
I
Y
Q
S
V
T
L
G
A
M
H
F
Q
E
EGGVIKRG
T
K
R
H
P
T
V
G
D
Y
V
T
I
G
T
G
A
K
V
L
G
N
I
I
V
G
S
H
V
R
I
G
A
N
C
W
I
D
R
D
V
D
S
N
Q
T
V
Y
I----------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
71.06
44%
-85
- C2 -
-
4H7O
4
?
C:
[84-259]
--------------------------------------------------------------------------------------------------------------------------
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
-
G
V
P
A
R
I
V
G
R
P
Q
S
D
K
P
S
L
D
M
D
Q
Q
------------------------------------------------------------------------------------------
55
PsiBlast_CBE
70.98
44%
-82
- C2 -
-
4H7O
4
?
B:
[84-259]
--------------------------------------------------------------------------------------------------------------------------
D
I
C
A
T
V
N
R
D
P
A
V
S
M
Y
S
M
P
L
L
Y
L
K
G
Y
H
A
L
Q
G
Y
R
V
A
N
W
L
W
R
Q
G
R
K
A
L
A
T
Y
F
Q
N
Q
I
S
V
A
C
Q
V
D
I
H
P
A
A
R
I
G
R
G
I
M
L
D
H
A
T
G
I
V
I
G
E
T
A
V
V
E
D
D
V
S
I
L
Q
D
V
T
L
G
G
T
G
K
E
C
--------
G
D
R
H
P
K
I
R
E
G
V
M
I
G
A
G
A
K
I
L
G
N
I
E
V
G
E
G
A
K
I
G
S
G
S
V
V
L
Q
A
V
P
P
H
T
T
V
A
-
G
V
P
A
R
I
V
G
R
P
Q
S
D
K
P
S
L
D
M
D
Q
Q
------------------------------------------------------------------------------------------
140
HHSearch
70.69
39%
-124
- C2 -
-
3Q1X
1
?
A:
[100-267]
--------------------------------------------------------------------------------------------------------------------
K
R
T
L
K
T
D
L
I
A
A
Y
A
G
D
P
A
A
P
G
L
S
L
I
I
R
C
Y
P
G
F
Q
A
V
I
V
Y
R
I
A
H
V
L
Y
E
C
G
E
R
Y
Y
C
R
E
M
M
E
S
V
H
S
Y
T
S
I
D
I
H
P
G
A
S
I
K
G
H
F
F
I
D
H
G
V
G
V
V
I
G
E
T
A
I
I
G
E
W
C
R
I
Y
Q
S
V
T
L
G
A
M
H
F
Q
E
EGGVIKRG
T
K
R
H
P
T
V
G
D
Y
V
T
I
G
T
G
A
K
V
L
G
N
I
I
V
G
S
H
V
R
I
G
A
N
C
W
I
D
R
D
V
D
S
N
Q
T
V
Y
-----------------------------------------------------------------------------------------------------------------
139
HHSearch
70.67
45%
-121
- C2 -
-
4N69
1
?
B:
[91-255]
----------------------------------------------------------------------------------------------------------------------
A
A
V
A
D
L
R
A
A
R
E
R
D
P
A
C
V
S
Y
S
H
C
L
L
N
Y
K
G
F
L
A
C
Q
A
H
R
V
A
H
L
L
W
R
Q
S
R
R
P
L
A
L
A
L
H
S
R
I
A
N
V
F
A
V
D
I
H
P
A
A
R
I
G
K
G
I
L
F
D
H
A
T
G
V
V
V
G
E
T
A
V
I
G
N
N
V
S
I
L
H
H
V
T
L
G
G
T
G
K
V
G
--------
G
D
R
H
P
K
I
G
D
G
V
L
I
G
A
G
A
T
I
L
G
N
I
K
I
G
E
G
A
K
V
G
A
G
S
V
V
L
I
D
V
P
P
R
T
T
A
V
-
G
N
P
A
R
L
V
---------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
68.54
45%
-126
- C2 -
-
4N69
1
?
B:
[95-255]
--------------------------------------------------------------------------------------------------------------------------
D
L
R
A
A
R
E
R
D
P
A
C
V
S
Y
S
H
C
L
L
N
Y
K
G
F
L
A
C
Q
A
H
R
V
A
H
L
L
W
R
Q
S
R
R
P
L
A
L
A
L
H
S
R
I
A
N
V
F
A
V
D
I
H
P
A
A
R
I
G
K
G
I
L
F
D
H
A
T
G
V
V
V
G
E
T
A
V
I
G
N
N
V
S
I
L
H
H
V
T
L
G
G
T
G
K
V
G
--------
G
D
R
H
P
K
I
G
D
G
V
L
I
G
A
G
A
T
I
L
G
N
I
K
I
G
E
G
A
K
V
G
A
G
S
V
V
L
I
D
V
P
P
R
T
T
A
V
-
G
N
P
A
R
L
V
---------------------------------------------------------------------------------------------------------