@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VM99: (2017-11-07 )
MQKFMNGWVNGFIGVAIFAGSLPATRVAVTGFEPGFLTAARAVIAGVLGLILIFLLKEKKPAKQDWWPLAIVALGVVVGFPLFTALALQYMNAAHSIVFVSLLPLATAIFAVVRGGEKPNLFFWIFAVLGSLVVFTYMFFLSGEASFGIGDLYMLIAIILCGFGYAEGGVLSKKIGGWQVICWALILALPIMLLATLFYMPVSFQDVSTSAVAGLVYVSLFSMLIGFFFWYKGLAQGGIAAISQLQLLQPLMGLAIAALLLHEHVSWSMLMVTAVTILCVAAAKKFA
Atome Classification :
(17 SA)
------------------------------------.....---------...-.10------...---------------......20.--....-...30.------.-----------------......40...-----.---...--.50..--------....-.-----.-60--....---..-----..----70......-..80........-.90..-----......------100......---.110.-----..-....120...---------..---------------.-.130..-.-..-.----.140--...----.....----150.....-----..160---..---...-----------.-.--170...-----..--.----.-------------180----------........190------------------.---.......200------------------.....------------..---------------.210.......220...--..---------------..-230....--------...-240...---------.....250....--...-260.-...------------------....270..------..-...280.....-----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------
M
Q
K
F
M
---------
N
G
W
-
V
N
-------
G
F
I
---------------
G
V
A
I
FAGSL--PA
T
R
-
V
A
VTGF------E-----------------
P
G
F
L
T
A
A
R
A
V
I
-----
A
---
G
V
L
--
G
L
I
L
I
--------
F
L
LK-E-----K-KP--AKQD---W
W
-----
P
L
----
A
I
V
A
L
G
V
V
-
V
G
F
-
P
L
F
T
A
L
A
L
-
Q
Y
M
N
A-----A
H
S
I
V
F
------
V
S
L
L
P
L
A
T
A
---
I
F
A
V
V
-----RG-GEKPN
L
F
F
W
I
---------
F
A
---------------
V
-
L
G
S
L
V
V
-
F
-
T
Y
-
M
----
F
F
-L--SGE----ASFG
I
----
G
D
L
Y
M
L
I
A
-----
I
I
L
CG---FG---YAE-----------G-G--
V
L
SKKI-----G
G
--
W
----
Q
-------------
V
I
-----------
C
W
A
L
I
L
A
L
P
I
-------------------
M
---
L
L
A
T
L
F
YMP-------------------VSFQD------------V
S
---------------
T
S
A
V
A
G
L
V
Y
V
S
L
F
S
M
L
I
--
G
F
---------------
F
F
-
W
Y
K
G
LAQ--------
G
G
I
-
A
-
A
I
S
Q
---------
L
Q
L
L
Q
P
L
M
G
L
A
I
--
A
A
L
-
L
L
-
H
-EHV------------------
S
W
S
M
L
M
V
T
A
------
V
T
-
I
L
C
V
A
A
A
K
KFA-----
9
Fugue
87.53
18%
-185
- C5 -
-
5I20
7
?
A:
[2-290]
--------------------------------------
S
R
S
---------
S
A
T
-
L
I
-------
G
F
T
---------------
A
I
L
L
W
--
S
T
--
L
A
L
A
-
T
S
S
T
G
A
------
V
-----------------
P
P
F
L
L
T
A
L
T
F
T
-----
I
---
G
G
A
--
V
G
I
A
A
--------
G
L
A
R
-
G
-----
V
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--
L
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----
W
-----
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V
----
W
V
H
G
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L
-
F
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Y
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Y
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A
L
-
K
L
A
P
P
-----
A
E
A
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L
V
------
A
Y
L
W
P
L
L
I
V
---
L
F
S
A
F
-----
L
P
-
G
E
R
L
R
P
A
H
V
A
---------
G
A
---------------
L
-
M
G
L
A
G
T
-
V
-
V
L
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L
----
G
A
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----
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----
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A
A
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S
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Y
-
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--
V
A
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-----
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T
----
E
-------------
V
V
-----------
A
G
F
C
L
A
T
A
A
L
-------------------
S
---
A
L
C
H
I
L
F
E
P
-------------------
S
V
W
--------------
P
V
---------------
G
S
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W
L
A
V
V
A
L
G
I
G
P
V
G
I
--
A
F
---------------
Y
T
-
W
D
I
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M
K
R
--------
G
D
V
-
R
-
L
L
G
V
---------
L
S
Y
A
A
P
V
L
S
T
L
L
--
L
V
V
-
A
G
-
F
-
A
A
P
------------------
S
G
A
L
A
I
A
C
A
------
L
I
-
V
G
G
A
A
V
A
T
L
L
A
RRLES
5
HHSearch
81.80
18%
-175
- C5 -
-
5I20
3
?
E:
[2-284]
--------------------------------------
S
R
S
---------
S
A
T
-
L
I
-------
G
F
T
---------------
A
I
L
L
W
S
T
L
A
--
L
A
T
S
--
S
T
G
A
V
------
P
-----------------
P
F
L
L
T
A
L
T
F
T
I
-----
G
---
G
A
V
--
G
I
A
A
G
--------
L
A
R
G
-
V
-----
G
L
S
V
--
L
R
Q
P
---
W
P
------
V
----
W
V
H
G
I
G
G
L
-
F
G
Y
-
H
F
F
Y
F
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A
L
-
K
L
A
P
P
-----
A
E
A
G
L
V
------
A
Y
L
W
P
L
L
I
V
---
L
F
S
A
F
-----
L
P
-
G
E
R
L
R
P
A
H
V
A
---------
G
A
---------------
L
-
M
G
L
A
G
T
-
V
-
V
L
-
L
----
G
A
-
R
--
A
G
G
FGFA
P
E
Y
V
P
----
G
Y
L
A
A
A
A
C
-----
A
V
I
W
S
---
V
Y
---
S
V
A
-----------
S
-
R
--
R
F
A
R
-
V
-----
P
T
--
E
----
V
-------------
V
A
-----------
G
F
C
L
A
T
A
A
L
S
-------------------
A
---
L
C
H
I
L
F
E
P
S
----------------------
V
W
------------
P
V
---------------
G
S
E
W
L
A
V
V
A
L
G
I
G
P
V
G
I
--
A
F
---------------
Y
T
-
W
D
I
G
M
K
R
--------
G
D
V
-
R
-
L
L
G
V
---------
L
S
Y
A
A
P
V
L
S
T
L
L
--
L
V
V
-
A
G
-
F
-
A
A
P
------------------
S
G
A
L
A
I
A
C
A
------
L
I
-
V
G
G
A
A
V
A
T
L
L
------
6
HHSearch
76.01
18%
-168
- C5 -
-
5I20
6
?
D:
[2-284]
--------------------------------------
S
R
S
---------
S
A
T
-
L
I
-------
G
F
T
---------------
A
I
L
L
W
S
T
L
A
--
L
A
T
S
--
S
T
G
A
V
------
P
-----------------
P
F
L
L
T
A
L
T
F
T
I
-----
G
---
G
A
V
--
G
I
A
A
G
--------
L
A
R
G
-
V
-----
G
-----
L
R
Q
P
---
W
P
------
V
----
W
V
H
G
I
G
G
L
-
F
G
Y
-
H
F
F
Y
F
S
A
L
-
K
L
A
P
P
-----
A
E
A
G
L
V
------
A
Y
L
W
P
L
L
I
V
---
L
F
S
A
F
-----
L
P
-
G
E
R
L
R
P
A
H
V
A
---------
G
A
---------------
L
-
M
G
L
A
G
T
-
V
-
V
L
-
L
----
G
A
----
A
G
G
FGFA
P
E
Y
V
P
----
G
Y
L
A
A
A
A
C
-----
A
V
I
W
S
---
V
Y
---
S
V
A
-----------
S
-
R
--
R
F
A
R
-
V
-----
P
T
--
E
----
V
-------------
V
A
-----------
G
F
C
L
A
T
A
A
L
S
-------------------
A
---
L
C
H
I
L
F
E
P
S
----------------------
V
W
------------
P
V
---------------
G
S
E
W
L
A
V
V
A
L
G
I
G
P
V
G
I
--
A
F
---------------
Y
T
-
W
D
I
G
M
K
R
--------
G
D
V
-
R
-
L
L
G
V
---------
L
S
Y
A
A
P
V
L
S
T
L
L
--
L
V
V
-
A
G
-
F
-
A
A
P
------------------
S
G
A
L
A
I
A
C
A
------
L
I
-
V
G
G
A
A
V
A
T
L
L
------
12
Fugue
60.59
20%
-108
- C6 -
-
4QT9
-
?
A:
[19-432]
------LS
D
D
A
L
M
D
T
V
Q
R
R
T
F
L
Y
F
W
EGAEPNSGLAP
E
R
Y
H
V
---------
D
G
V
-
Y
P
-------
Q
N
D
---------------
A
N
V
V
T
S
G
G
S
--
G
F
G
I
M
A
I
L
A
G
I
------
D
-----------------
R
G
Y
V
T
R
E
E
G
L
A
-----
R
M
--
E
-----
R
I
V
S
--------
F
L
E
K
-
A
-----
D
-
R
F
HG
A
Y
P
H
---
W
W
YGD--
T
G
----
K
V
K
P
F
G
Q
K
D
N
G
G
-
D
L
V
E
T
A
F
L
M
Q
G
L
L
A
-----
V
H
Q
Y
Y
A
NGN
D
K
E
K
A
I
A
Q
R
I
D
R
---
L
W
R
E
V
DWDWY
R
K
-
G
G
Q
N
V
L
Y
W
H
W
SPTYGWEMD
F
P
---------------
I
-
H
G
Y
N
E
C
M
I
M
Y
I
-
L
----
A
A
-
A
--
S
P
T
----
H
G
-------------
V
P
-----
A
A
V
Y
H
---
D
G
---
W
A
Q
-----------
N
-
G
AI
V
S
P
H
K
V
-----
E
G
--
I
----
E
-------------
L
H
LRYQGTEAGP
L
F
W
A
Q
Y
S
F
L
G
L
DPVGLKDEYCPS
Y
F
H
E
M
R
N
L
---
T
L
V
N
R
A
Y
C
I
R
NPKHYKGFGPD
C
W
G
L
T
AS
Y
S
V
D
G
------------
Y
A
AHSPNEQDDKGVISP
T
A
A
L
S
S
I
V
Y
T
P
E
Y
S
L
Q
V
M
R
H
L
---------------
Y
N
M
G
D
K
V
F
G
P
--------
F
G
F
-
Y
D
A
F
S
E
---------
T
D
N
W
Y
P
Q
R
Y
L
A
I
D
Q
G
P
I
-
A
V
M
I
-
E
N
Y
------------------
R
T
G
L
L
W
K
L
F
M
-----
S
H
-
P
D
V
Q
A
G
L
T
K
L
G
FNTN-
10
Fugue
60.26
16%
-88
* C6 *
-
4Z4J
6
?
A:
[11-402]
-------------GS
M
D
I
T
R
F
K
E
D
L
K
A
H
L
E
E
K
I
I
P
F
W
Q
S
L
K
---------
D
D
E
-
F
G
-------
G
Y
Y
---------------
G
Y
M
D
F
N
L
N
I
DR
K
A
Q
K
-
G
C
I
L
N
S
------
R
-----------------
I
L
W
F
F
S
A
C
Y
N
V
LKS
E
K
C
---
K
E
M
--
A
F
H
A
F
--------
E
F
L
K
-
N
-----
K
-
F
W
--
D
K
E
Y
E
G
L
F
W
-----
S
V
SHKG
V
P
V
D
V
T
K
H
-
V
Y
V
-
Q
A
F
G
I
Y
G
L
-
S
E
Y
Y
E
-----
A
S
G
D
--------
E
E
A
L
H
M
A
K
R
---
L
F
E
I
L
-----
E
T
K
C
K
R
E
N
G
Y
T
E
Q
---------
F
E
RNWQ
E
K
E
N
RFLSENG
V
-
I
A
S
K
T
M
-
N
-
T
H
-
L
----
H
V
-
L
--
E
S
Y
----
T
N
L
Y
R
L
LKL
D
D
V
Y
E
A
L
E
-----
W
I
V
R
L
---
F
V
D
KI
Y
K
K
-----------
G
T
G
--
H
F
K
V
F
C
D----
D
N
--
W
NELI
K
-------------
A
V
-----------
S
Y
G
H
D
I
E
A
S
W
-------------------
L
---
L
D
Q
A
A
K
Y
L
K
D------------------
E
K
L
K
E
------------
E
V
---------------
E
K
L
A
L
E
V
A
Q
I
T
L
K
E
A
F
D
--
G
Q
S
L
I
N
E
MIEDRIDRSK
I
W
-
W
V
E
A
E
T
V
--------
V
G
F
-
F
-
N
A
Y
Q
---------
K
T
K
E
E
K
Y
L
D
A
A
I
--
K
T
W
E
F
I
-
K
-
E
H
L
VDRRKNSEWLWKVNEDLE
A
V
N
M
P
I
V
E
Q
WKCP
Y
H
N
G
-
R
M
C
L
E
I
I
K
R
V
D
-----
18
Fugue
52.88
18%
-75
* C5 *
-
4IIK
3
SIDD_LEGPH
A:
[1-314]
------------------------------------
M
R
S
I
I
---------
T
Q
I
-
C
N
-------
G
V
L
HG
Q
S
Y
Q
SGSNDLDKG
N
S
E
I
F
A
S
S
L
--
F
-
V
H
-
L
N
E
Q
G
K
------
E
-----------------
I
K
--
D
S
D
D
K
I
V
-----
I
---
G
Y
T
KD
G
M
A
F
Q
--------
I
V
V
D
G
F
-----
Y
-
G
C
--
E
R
Q
A
---
V
F
-----
S
F
----
I
D
N
Y
V
------
L
-
P
L
I
D
N
F
S
L
-
D
L
T
R
Y
-----
P
D
S
K
K
V
------
T
E
--
S
L
I
H
T
---
I
Y
S
L
------
R
S
-
K
H
A
P
---------------
L
A
---------------
E
-
F
T
M
S
L
C
-
V
-
T
Y
-
Q
K
DE
Q
L
F
-
C
--
A
G
-------
F
G
I
----
G
D
T
G
I
A
I
K
-----
R
---
N
---
E
G
---
T
I
E
-----------
Q
-
L
--
V
C
H
T
E
V
-----
D
G
--
F
----
K
DAFDNYSSAN
I
D
L
V
I
-----------
E
R
N
S
V
F
N
T
K
V
-------------------
M
PG
D
E
L
V
G
Y
T
Y
V
P
-------------------
P
M
L
E
M
------------
T
E
---------------
K
E
F
E
V
E
K
R
I
V
R
H
L
N
L
D
P
--
G
N
---------------
F
D
-
D
K
D
P
L
F
S
--------
Q
L
L
-
Q
-
V
V
K
S
---------
K
Q
K
Q
L
V
E
Q
A
K
E
T
--
G
Q
I
-
Q
R
-
F
G
D
D
F
------------------
T
V
G
R
L
V
I
P
D
------
Q
L
-
L
I
N
Q
L
R
I
H
A
L
S
-----
14
Fugue
50.26
17%
-130
- C2 -
-
1W5C
-
PSBD_THEEB
D:
[1-350]
-----------------------MTIAIG
R
A
P
A
E
RG
W
F
D
I
L
---------
D
D
W
-
L
K
R
DRFVFV
G
W
S
---------------
G
I
L
L
F
P
C
A
Y
--
L
A
L
G
-
G
W
L
T
G
T
------
T
FVTSWYTHG
L
A
S
S
YLEG
C
N
F
L
T
V
A
V
S
T
P
-----
A
---
N
S
M
--
G
H
S
L
L
--------
L
L
W
G
-
P
-----
E
-
A
Q
--
G
D
F
T
---
R
W
C
Q
L
GG
L
W
----
T
F
I
A
L
H
G
A
-
F
G
L
-
I
G
F
M
L
R
Q
F
-
E
I
A
R
L
V
GVRP
Y
N
A
I
A
F
------
S
A
P
I
A
V
F
V
S
---
V
F
L
I
Y
-----
P
L
-
G
Q
S
S
----
W
F
---------
F
A
---------------
P
S
F
G
V
A
A
I
-
F
-
R
F
-
L
----
L
F
-
F
--
Q
G
F
----
H
N
W
T
L
----
N
P
F
H
M
M
G
V
-----
A
G
V
L
G
G
A
L
L
C
---
A
I
H
-----------
G
-
A
--
T
V
E
N
T
L
FQDGE
G
A
--
S
----
T
-------------
F
R
-----------
A
F
N
P
T
Q
A
E
E
T
-------------------
Y
---
S
M
V
T
A
N
R
F
W
-------------------
S
Q
I
F
G
------------
I
A
---------------
F
S
N
K
R
W
L
H
F
F
M
L
F
V
P
V
T
--
G
L
---------------
W
M
-
S
A
I
G
V
V
G
L
ALNLRSY
D
F
I
-
S
-
Q
E
I
R
---------
A
A
E
D
P
E
F
E
T
F
Y
T
--
K
N
L
-
L
L
-
N
-
E
G
I
------------------
R
A
W
M
A
P
Q
D
Q
------
P
H
-
E
N
F
V
F
P
E
E
V
L
P
RGN--
17
Fugue
43.17
15%
-45
- C6 -
-
5JUF
-
?
A:
[1-299]
MN
L
K
D
S
I
G
L
R
I
K
T
E
R
E
R
Q
QMS
R
E
V
L
C
LDGAELT
V
R
Q
L
I
R
I
E
---------
K
G
E
S
L
P
-------
S
L
D
---------------
R
L
S
Y
I
A
K
R
L
--
G
K
S
M
-
T
E
L
L
D
Q
------
D
-----------------
N
--
I
T
I
P
D
E
Y
Y
-----
E
---
M
K
N
--
R
L
I
K
F
--------
P
T
Y
R
-
N
-----
P
-
D
R
--
I
K
S
K
---
L
T
-----
L
I
----
E
E
V
Y
E
K
F
F
-
D
I
L
-
P
E
E
E
L
L
T
L
-
D
I
L
E
N
-----
I
L
S
F
T
S
------
W
E
E
S
P
K
V
E
E
---
I
Y
E
D
L
-----
F
E
-
Q
V
K
R
K
---
R
K
---------
F
S
---------------
T
-
N
D
L
L
V
I
-
D
-
Y
Y
-
F
----
F
H
-
L
--
Y
G
R
----
K
Q
Y
D
K
----
K
L
F
E
R
I
I
K
-----
R
V
L
---------------------------------
N
Q
-----
E
I
--
W
----
T
-------------
D
D
-----------
V
Y
N
I
V
L
F
N
D
L
-------------------
M
---
A
I
A
A
L
K
I
F
H
-------------------
N
S
F
S
D
------------
F
L
---------------
T
V
V
D
K
A
L
A
V
I
E
K
S
Q
L
---------------------------
Y
S
Y
K
--------
P
S
V
-
F
-
V
L
K
A
---------
K
Y
E
L
L
H
K
E
N
K
K
E
--
A
A
E
-
N
Y
-
D
-
K
A
I
------------------
V
F
A
S
V
L
E
D
S
------
V
L
-
E
E
S
I
K
A
G
K
L
A
D
GL---
15
Fugue
39.78
13%
-70
- C1 -
-
1QAG
-
UTRO_HUMAN
A:
[31-255]
----------------------------------D
V
Q
K
K
T
F
---------
T
K
W
-
I
N
-------
A
R
F
---------------
S
-----------
K
S
G
-
K
P
P
I
N
D
M-----
F
-----------------
T
D
L
K
D
--------------------
G
R
K
L
L
--------
D
L
L
E
-
G
-----
L
-
T
G
--
T
S
L
P
---
K
E
-----
R
------------------
G
S
T
R
V
H
A
L
-
N
N
V
N
R
-----
V
L
Q
V
L
H
------
Q
N
N
V
E
L
V
N
I
---
G
G
T
D
I
-----
V
D
-
G
N
H
K
L
T
L
G
L
L
---------
W
S
---------------
I
-
I
L
H
W
Q
V
-
K
-
D
V
M
K
----
D
V
M
S
--
D
L
Q
----
Q
T
N
S
E
----
K
I
L
L
S
W
V
R
-----
Q
T
T
R
P
-----------------------------------------------------------------------------------------------------------------
Y
S
Q
-------------------
V
N
V
L
N
------------
F
T
---------------
T
S
W
T
D
G
L
A
F
N
A
V
L
H
R
H
K
--
P
D
---------------
L
F
-
S
W
D
K
V
V
K
M-------
S
P
I
-
E
-
R
L
E
H
A
--------
F
S
K
A
Q
T
Y
L
G
--
I
--
E
K
L
-
L
D
-
P
-
E
D
V
------------------
A
V
R
L
P
D
K
K
S
------
I
I
M
Y
-
L
T
S
L
F
E
V
L
P
-----
4
PsiBlast_PDB
34.51
33%
-88
- C7 -
-
3ALE
-
CUS_ORYSJ
A:
[328-399]
--------------------------------------------------------------------------------------------------
A
A
L
G
L
------
E
-----------------
P
G
K
L
A
A
S
R
R
V
L
-----
S
D
YG
N
M
S
--
G
A
T
V
I
--------
F
A
L
D
-
E
L
R
R
Q
R
K
-------------
W
-----
P
--------
E
L
G
V
M
-
M
A
F
G
P
G
M
T
V
D
A
M
-
L
L
H
A
T
-----
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
32.95
10%
-101
- C4 -
-
3DZO
-
?
A:
[13-382]
--------N
L
Y
F
Q
G
FRGTDPG
D
V
V
I
E
E
L
F
N
R
I
PQAN
V
R
T
T
S
---------
E
Y
A
-
A
D
-------
S
L
V
---------------
S
T
S
L
W
N
T
G
Q
--
P
F
R
V
-
E
S
E
L
G
E
------
R
-----------------
P
R
T
L
V
R
G
T
V
L
G
-----
Q
---
E
D
P
--
Y
A
Y
L
E
--------
A
T
D
Q
-
E
-----
T
-
G
E
----------------
S
F
----
E
V
H
V
P
Y
F
T
-
E
R
A
-
I
K
Q
M
K
E
E
V
-
L
R
L
R
L
-----
L
R
G
I
K
N
------
Q
K
Q
A
K
V
H
L
R
FIF
P
F
D
L
V
-----
K
D
-
P
Q
V
L
S
R
F
F
L
Y
---------
P
R
---------------
M
-
Q
S
N
L
Q
T
-
F
-
G
E
-
V
----
L
L
-
S
H
S
S
T
H
----
K
S
L
V
H
----
H
A
R
L
Q
L
T
L
-----
Q
V
I
R
L
---
L
A
---
S
L
H
H
Y
GLVHTYLRP
V
-
D
--
I
V
L
D
Q
R
-----
G
G
--
V
----
F
-------------
L
T
-----------
G
F
E
H
L
V
R
D
G
A
-------------------
S
AVS
P
I
G
R
G
F
A
P
P
-------------------
E
T
T
A
E
R
M
LPFGQHH
P
T
L
M
T
---------------
F
A
F
D
T
W
T
L
G
L
A
I
Y
W
I
W
C
--
A
D
---------------
L
P
-
N
T
D
D
A
A
L
--------
G
G
S
-
E
-
W
I
F
R
SCKNIP
Q
P
V
R
A
L
L
E
G
F
L
R
Y
P
K
--
E
D
R
-
L
L
-
P
-
L
Q
A
------------------
M
-
E
T
P
E
Y
E
Q
------
L
R
-
T
E
L
S
A
A
L
P
L
Y
Q
-----
1
PsiBlast_PDB
32.92
31%
0
- C- -
-
5UAR
-
CFTR_DANRE
A:
[88-425]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
L
Y
I
G
E
-----
A
T
K
T
V
Q
------
P
Q
L
L
G
R
I
I
A
---
S
F
D
P
A
-----
H
E
-
P
E
R
A
N
G
Y
F
L
A
---------
F
-------------------
G
L
G
L
L
-
F
-
T
A
-
R
----
F
L
-
L
--
L
Q
P
----
A
M
F
G
L
----
H
H
L
G
M
Q
I
R
-----
I
A
L
F
S
---
I
I
---
Y
K
K
-----------
T
-
L
--
K
L
S
S
R
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
31.79
31%
-151
- C3 -
-
5W81
-
?
A:
[88-457]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
L
Y
I
G
E
-----
A
T
K
T
V
Q
------
P
Q
L
L
G
R
I
I
A
---
S
F
D
P
A
-----
H
E
-
P
E
R
A
N
G
Y
F
L
A
---------
F
-------------------
G
L
G
L
L
-
F
-
T
A
-
R
----
F
L
-
L
--
L
Q
P
----
A
M
F
G
L
----
H
H
L
G
M
Q
I
R
-----
I
A
L
F
S
---
I
I
---
Y
K
K
-----------
T
-
L
--
K
L
S
S
R
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
30.89
11%
-73
- C6 -
-
2NYG
1
YOKD_BACSU
A:
[2-271]
------------------------------------
L
K
K
I
V
E
S
TT
F
P
R
T
K
Q
S
I
-
T
E
-------
D
L
K
---------------
A
L
G
L
K
K
G
M
T
--
V
L
V
H
-
S
S
L
S
S
I
GWVNGG
A
-----------------
V
A
V
I
Q
A
L
I
D
V
V
-----
T
---
E
E
G
--
T
I
V
M
P
SQSVELSD
P
K
E
W
-
G
-----
N
-
P
P
--
V
P
E
E
---
W
W
-----
D
I
----
I
R
E
S
M
--------
P
A
Y
N
S
N
Y
T
-
P
T
T
R
G
-----
M
G
---------------
Q
I
V
E
---
L
F
R
S
Y
-----
P
E
-
V
K
R
S
N
H
P
N
Y
S
---------
F
V
---------------
A
-
W
G
K
H
-
K
-
N
-
K
I
-
L
----
N
Q
-
H
--
P
L
E
----
F
G
L
G
E
----
Q
S
P
L
G
K
L
Y
I
R
E
S
Y
V
L
L
L
G
---
A
D
---
F
D
S
-------------------------------
S
----
T
-------------
C
F
-----------
H
L
A
E
Y
R
I
P
Y
Q
-------------------
K
---
I
I
N
R
G
A
P
I
I
-------------------
V
E
G
K
R
------------
V
W
---------------
K
E
Y
K
E
L
E
F
R
E
E
L
F
Q
E
V
G
--
Q
A
---------------
F
E
-
A
E
H
N
M
K
V
--------
G
K
V
G
S
-
A
N
C
R
---------
L
F
S
L
T
E
A
V
D
F
A
E
--
K
W
F
-
I
N
-
N
-
D
S
K
------------------
N
I
--------------------------------
8
HHSearch
30.68
14%
-152
- C5 -
-
5I20
2
?
E:
[148-286]
--------------------------------------
E
Y
V
---------
P
G
Y
-
L
A
-------
A
A
A
---------------
C
A
V
I
W
S
V
Y
S
--
V
A
S
R
-
R
F
A
R
-
V
------
P
-----------------
T
E
V
V
A
G
F
C
L
A
T
-----
A
---
A
L
S
--
A
L
C
H
I
--------
L
F
E
P
-
S
-----
V
-
W
P
--
V
G
S
E
---
W
L
-----
A
V
----
V
A
L
G
I
G
P
V
-
G
I
A
-
F
Y
T
W
D
I
G
M
-
K
R
G
D
V
-----
R
L
L
G
V
L
------
S
Y
A
A
P
V
L
S
T
---
L
L
L
V
V
-----
A
G
-
F
A
A
P
S
G
A
L
A
I
---------
A
C
---------------
A
-
L
I
V
G
G
A
-
A
-
V
A
-
T
----
L
L
-
A
--
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
30.51
14%
-158
- C5 -
-
5I20
5
?
D:
[148-285]
--------------------------------------
E
Y
V
---------
P
G
Y
-
L
A
-------
A
A
A
---------------
C
A
V
I
W
S
V
Y
S
--
V
A
S
R
-
R
F
A
R
-
V
------
P
-----------------
T
E
V
V
A
G
F
C
L
A
T
-----
A
---
A
L
S
--
A
L
C
H
I
--------
L
F
E
P
-
S
-----
V
-
W
P
--
V
G
S
E
---
W
L
-----
A
V
----
V
A
L
G
I
G
P
V
-
G
I
A
-
F
Y
T
W
D
I
G
M
-
K
R
G
D
V
-----
R
L
L
G
V
L
------
S
Y
A
A
P
V
L
S
T
---
L
L
L
V
V
-----
A
G
-
F
A
A
P
S
G
A
L
A
I
---------
A
C
---------------
A
-
L
I
V
G
G
A
-
A
-
V
A
-
T
----
L
L
-
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
12.96
33%
-
* C7 *
-
3OIT
-
CUS_ORYSJ
A:
[328-399]
--------------------------------------------------------------------------------------------------
A
A
L
G
L
------
E
-----------------
P
G
K
L
A
A
S
R
R
V
L
-----
S
D
YG
N
M
S
--
G
A
T
V
I
--------
F
A
L
D
-
E
L
R
R
Q---------------------
P
--------
E
L
G
V
M
-
M
A
F
G
P
G
M
T
V
D
A
M
-
L
L
H
A
T
-----
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------