@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMB7: (2017-11-07 )
MKVLICDDEPLAVERLSRLVSKMGHEVVATAHHGQDALEQARLHHPDVILLDIQMPGMNGLVCAEQLSQLNPRPAIVFCTAYDQHALEAFKSQAQAYLLKPIDPQELEQTFKQLTQLTQAQLSALPKPELLQDLKTQRHQIAAKTYRGVELIPVENIYYFLADQKYVTVRHKNGSVLIDETLKELETEFADQFIRIHRNALVSIAYLDGLELVSSGQYQVRLRGLDERLSVSRRHLSTLRERIHQL
Atome Classification :
(20 SA)
.........10........20-..-..-....30........40........50........60........70...---.....80.--.--.--.--.--.--..90........100.......110.......120.......130.......140.......150.......160.......170...--....180.......190.....----..200.......210.......220.......230.......240....-----------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
V
L
I
CDDE
P
L
A
V
E
R
L
S
R
L
V
S
-KM-GH-
E
V
V
A
T
AHH
G
Q
D
A
L
E
Q
A
RLHHP
D
V
I
L
L
D
I
QMPGMN
G
L
V
C
A
E
Q
L
S
QLNPR
P
---
A
I
V
F
C
TA
Y
--
D
--
Q
--
H
--
A
--
L
--
E
A
F
K
S
Q
A
Q
A
Y
LLKPI
D
P
Q
E
L
E
Q
T
F
K
Q
L
T
Q
L
T
Q
A
Q
L
SALP
K
P
E
L
L
Q
D
L
K
T
Q
R
H
Q
I
A
A
K
TYR
G
V
E
L
I
PVE
N
I
Y
Y
F
LAD
Q
K
Y
V
T
V
R
HKNG
S
--
V
L
I
D
E
T
L
K
E
L
E
T
E
F
A
D
Q
F
I
R
I
H
----
R
N
A
L
V
S
I
A
Y
LD
G
L
E
L
VSSG
Q
Y
Q
V
R
LRG
L
D
E
R
L
S
V
S
R
R
H
L
S
T
L
R
E
R
I
HQL-----------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
79.85
33%
-108
- C1 -
-
2WB4
1
PLED_CAUCN
A:
[4-122]
-
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
-
A
E
-
Y
Y
-
E
V
-
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
-
D
P
T
T
RH
I
P
V
V
L
I
T
A
L
--
D
--
G
--
R
--
G
D
R
I
--
Q
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
L
T
R
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
79.38
18%
-48
- C1 -
-
1NY5
3
?
A:
[1-384]
M
N
V
L
V
I
E
D
D
K
V
F
R
G
L
L
E
E
Y
L
S
-
M
K
-
G
I
--
K
V
E
S
A
E
R
G
K
E
A
Y
K
L
L
S
E
K
H
F
N
V
V
L
L
D
L
L
L
P
D
V
N
G
L
E
I
L
K
W
I
K
E
R
S
P
E
T
---
E
V
I
V
I
T
G
H
GT
I
--
K
--
T
--
A
--
V
--
E
A
M
K
M
G
A
Y
D
F
L
T
K
P
C
M
L
E
E
I
E
L
T
I
N
K
A
I
E
H
R
K
L
R
K
E
N
E
L
L
R
R
E
K
D
L
K
E
E
E
Y
V
F
E
S
P
K
M
K
E
I
L
E
K
I
K
K
I
-----
S
C
A
E
C
P
V
L
I
T
G
E
S
G
V
G
K
E
V
V
A
R
L
I
H
K
L
S
D
R
S
K
E
P
F
V
A
L
N
VASI
P
R
D
I
F
E
A
E
L
F
G
Y
E
K
G
A
F
T
G
A
V
S
S
K
-
E
G
F
F
E
L
A
D
G
G
T
L
F
L
D
E
I
G
E
L
S
L
E
A
Q
A
K
L
L
R
V
I
E
SG
K
F
Y
R
LGGRK
E
I
E
V
N
V
R
I
L
A
A
T
NRN
I
K
E
L
V
K
E
GKFR
E
D
L
Y
Y
R
L
G
V
I
E
I
E
I
P
P
LRERKED
I
I
P
L
A
N
H
F
L
K
K
F
S
R
K
Y
AKEVEGFT
K
S
A
Q
E
L
L
L
S
YPWYGN
V
R
E
L
K
N
V
I
E
R
A
V
L
F
SEGKFID
R
G
E
L
S
C
L
V
1
PsiBlast_PDB
78.48
36%
-80
- C1 -
-
2QV0
-
MRKE_KLEPN
A:
[58-179]
M
K
V
I
I
V
E
D
E
F
L
A
Q
Q
E
L
S
W
L
I
N
-
T
H
-
S
Q
M
E
I
V
G
S
F
D
D
G
L
D
V
L
K
F
L
Q
H
N
K
V
D
A
I
F
L
D
I
N
I
P
S
L
D
G
V
L
L
A
Q
N
I
S
Q
F
A
H
K
P
---
F
I
V
F
I
T
A
W
--
K
--
E
--
H
--
A
--
V
--
E
A
F
E
L
E
A
F
D
Y
I
L
K
P
Y
Q
E
S
R
I
I
N
M
L
Q
K
L
T
T
A
W
E
Q
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
77.92
27%
-50
- C1 -
-
4LDZ
2
DESR_BACSU
A:
[6-153]
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
N
L
E
D
-
D
M
-
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
D
T
G
C
K
I
---
I
I
L
T
T
F
A
R
--
P
--
G
--
Y
--
F
--
Q
--
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
R
S
V
--
M
N
G
K
R
I
Y
A
---
P
E
L
M
E
D
L
Y
S
E
A
N
P
L
T
D
R
E
K
E
V
L
E
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
77.06
33%
-114
- C1 -
-
1NXV
-
?
A:
[3-119]
-
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
-
K
E
-
G
Y
-
E
V
V
-
T
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
M
L
P
E
I
D
G
L
E
V
A
K
T
I
R
K
T
S
S
V
P
----
I
L
M
L
S
A
K
--
D
--
S
--
E
F
D
K
--
V
--
I
G
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
Q
A
R
V
K
A
L
L
R
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
HHSearch
77.05
31%
-89
- C1 -
-
3HDG
-
?
E:
[9-123]
-
K
I
L
I
V
E
D
D
T
D
A
R
E
W
L
S
T
I
I
S
-
N
H
-
F
P
-
E
V
W
-
S
A
G
D
G
E
E
G
E
R
L
F
G
L
H
A
P
D
V
I
I
T
D
I
R
M
P
K
L
G
G
L
E
M
L
D
R
I
K
A
G
G
A
K
P
---
Y
V
I
V
I
S
A
F
--
S
--
E
MK
Y
--
F
--
I
--
K
A
I
E
L
G
V
H
L
F
L
P
K
P
I
E
P
G
R
L
M
E
T
L
E
D
F
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
76.47
35%
-149
- C1 -
-
5ED4
1
?
A:
[25-139]
-
R
V
L
V
V
D
D
E
A
N
I
V
E
L
L
S
V
S
L
K
-
F
Q
-
G
F
-
E
V
Y
-
T
A
T
N
G
A
Q
A
L
D
R
A
R
E
T
R
P
D
A
V
I
L
D
V
M
M
P
G
M
D
G
F
G
V
L
R
R
L
R
A
D
G
I
D
A
---
P
A
L
F
L
T
A
R
--
D
SL
Q
--
D
--
K
--
I
--
A
G
L
T
L
G
G
D
D
Y
V
T
K
P
F
S
L
E
E
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
76.41
30%
-93
- C1 -
-
4IGA
-
CHEY_THEMA
A:
[7-121]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
C
S
A
M
--
G
--
Q
--
Q
--
A
--
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
75.59
33%
-117
- C1 -
-
1NXW
1
?
A:
[3-119]
-
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
-
K
E
-
G
Y
-
E
V
V
-
T
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
M
L
P
E
I
D
G
L
E
V
A
K
T
I
R
K
T
S
S
V
P
----
I
L
M
L
S
A
K
--
D
--
S
--
E
F
D
K
--
V
--
I
G
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
Q
A
R
V
K
A
L
L
R
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
75.25
31%
-107
- C- -
-
1U0S
-
CHEY_THEMA
Y:
[4-119]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
C
S
A
M
--
G
--
Q
--
Q
--
A
--
M
VI
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
75.20
27%
-47
- C1 -
-
3CZ5
-
?
A:
[7-141]
-
R
I
M
L
V
D
D
H
P
I
V
R
E
G
Y
R
R
L
I
E
-
R
R
P
G
Y
-
A
V
V
A
E
A
A
D
A
G
E
A
Y
R
L
Y
R
E
T
T
P
D
I
V
V
M
D
L
T
L
P
G
P
G
G
I
E
A
T
R
H
I
R
Q
W
D
G
A
A
---
R
I
L
I
F
T
M
H
QG
S
--
A
--
F
--
A
--
L
--
K
A
F
E
A
G
A
S
G
Y
V
T
K
S
S
D
P
A
E
L
V
Q
A
I
E
A
I
L
A
G
R
R
A
M
-----
S
P
D
I
A
Q
E
I
A
E
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
HHSearch
75.12
32%
-126
- C- -
-
1U0S
-
CHEY_THEMA
Y:
[4-115]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
C
S
A
M
--
G
--
Q
QA
M
--
V
--
I
--
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
74.95
33%
-107
- C1 -
-
1NXS
-
?
A:
[3-120]
-
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
-
K
E
-
G
Y
-
E
V
V
-
T
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
--
L
P
E
I
D
G
L
E
V
A
K
T
I
R
K
T
S
S
V
P
----
I
L
M
L
S
A
K
--
D
--
S
--
E
F
D
K
--
V
--
I
G
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
Q
A
R
V
K
A
L
L
R
R
S
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
74.64
30%
-106
- C1 -
-
2TMY
-
CHEY_THEMA
A:
[4-119]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
C
S
A
M
--
G
--
Q
--
Q
--
A
--
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.50
30%
-89
- C1 -
-
3TMY
-
CHEY_THEMA
A:
[4-119]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
C
S
A
M
--
G
--
Q
--
Q
--
A
--
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
HHSearch
74.45
30%
-102
- C1 -
-
4QYW
-
CHEY_THEMA
A:
[4-116]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
-
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
A
S
A
M
--
G
--
Q
Q
A
M
--
V
--
I
--
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
73.74
30%
-100
- C1 -
-
1TMY
-
CHEY_THEMA
A:
[4-119]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
C
S
A
M
--
G
--
Q
--
Q
--
A
--
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
73.60
33%
-111
- C1 -
-
1NXP
1
?
A:
[3-119]
-
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
-
K
E
-
G
Y
-
E
V
V
-
T
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
M
L
P
E
I
D
G
L
E
V
A
K
T
I
R
K
T
S
S
V
P
----
I
L
M
L
S
A
K
--
D
--
S
--
E
F
D
K
--
V
--
I
G
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
Q
A
R
V
K
A
L
L
R
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.53
29%
-94
- C1 -
-
4QYW
-
CHEY_THEMA
A:
[4-119]
-
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
-
K
A
-
G
Y
-
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
-
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
---
K
I
I
V
A
S
A
M
--
G
--
Q
--
Q
--
A
--
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
73.01
30%
-133
- C1 -
-
3A0U
3
?
A:
[3-114]
-
R
I
L
V
V
D
D
E
P
N
I
R
E
L
L
K
E
E
L
Q
-
E
E
-
G
Y
-
E
I
-
D
T
A
E
N
G
E
E
A
L
K
K
F
F
S
G
N
Y
D
L
V
I
L
D
I
E
M
P
G
I
S
G
L
E
V
A
G
E
I
R
K
K
K
K
D
A
---
K
I
I
L
L
T
A
Y
--
S
--
H
--
Y
--
R
--
S
--
D
L
S
S
W
A
A
D
E
Y
V
V
K
S
F
N
F
D
E
L
K
E
K
V
K
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------