@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMP3: (2017-11-09 )
MNMALKVSIASKSAHLTPEQIEEFGRRVEQIRQDVMQSLGEQDAKYIYKVRNFVRYTEIASRGMLMFGGWIPPVWLLGTGLLGISKIVENMELGHNVMHGQFDWLNEPSLNGNTYDWDTIASGDDWRETHNYVHHTYTNIVGKDHDIGYGILRVSDQQKWEPRHLFNIPLALQLMFFFEWYVGVQNLHLEDALVYKTKSWKQVWEDAAKVRKKATRQVLKDYVFFPVISGPMFLPVFAGNVVANIIRNLWSSAVIFNGHFTEDAETFEPDNTDTETKAEWYLRQIRGSSNFSGTEWLHFMSGNLSHQIEHHLFPDMPANRYKEVAPKIKALCAEYGINYNEANFMRQFWSVWVRLAKCSLPNHTTAKVMQTLEKLKAKFKFA
Atome Classification :
(20 SA)
----------.........10........20..-.------.----....30........40--.......-----.50..--..-..-----..60........70..---------------..---....80........--90..-----......100..----..-...110.---..-...-.120-------------------...-------------..-----...130.......140-.....-..-.150-..-----.--......160------------.....------...----------------170------.......------.-----------------------------.180..-------..------------..--.190--..-....----..200........210.--------------------------..------.-----------...220-...---.....230...---....----------------240---....---...250..--...-..260-----.---------........270-------------.------------........280..------......290.--------------.-.--------..----..300..----.-..----------------------..310...-..--..------320......-.330---....----....340-.-....------..350.....-------.---.360--------------........370.......380-----------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------MN
M
A
L
K
V
S
IASKSAHL
T
P
E
Q
I
E
E
-
F
------
G
----
R
R
V
E
Q
I
R
Q
D
V
M
Q
S
LG
E
--
Q
D
A
K
Y
I
Y
-----
K
V
R
N
F
--
V
R
-
Y
T
-----
E
I
A
SR
G
M
L
M
FGGWI
P
P
---------------
V
W
---
L
L
G
T
G
L
L
G
I
S
K
I
V
E
--
N
M
E
L-----GHNVMHGQFDW----LN-EPSLNGN---TY-DWD-TIA--------------------SGD-------------
D
W
-----
R
E
T
H
N
Y
V
H
H
T
Y
T
N
IV--GKDHD-I
G
-
Y
G
---
I
L
-----R--VSDQQKWE-------------PRHLF------N
I
P
----------------
L
--------
A
L
Q
L
M
F
F
------
F
-----------------------------
E
W
Y
V
G
V
-------QN------------LH--LED---A
L
-
V
YKT----
K
S
W
-
K
Q
V
W
E
D
A
A
K
V
R
K
K
--------------------------
A
T
------
R
-----------
Q
V
L
K
D
--
Y
V
F
---
F
PVISG
P
M
F
L
P
---
V
FA
G
----------------
N
V
V
---
A
N
I
I
---
R
N
L
WS
S
A
V
--
I
FN-GHF-------T---------EDAETFEPD---------------N------------TD
T
E
T
K
A
E
W
-
Y
L
R
------
Q
IRGSSNFSG--------------
T
-
E
--------
W
L
----
H
FMSGN
L
----
S
-
H
Q
----------------------
I
E
H
HLFPD-M
P
--
A
N
------
R
Y
K
E
V
A
P
K
I
-
K
A
L
----
C
A
EY----GINY
N
E
A
-
N
-
F
M
R
Q
------
F
W
S
V
W
V
R
L
A
K
-------C---SLP---------------NH
T
T
A
K
V
M
Q
T
L
E
K
L
K
A
KFKFA-----------------------------------------------------------------------
23
Fugue
62.21
13%
-3
* C7 *
-
1DBG
1
CSLB_PEDHD
A:
[26-506]
----------
Q
V
V
A
S
N
E
T
L
Y
Q
V
V
K
E
V
K
P
G
G
L
V
Q
-
I
------
A
----
D
G
T
Y
K
D
V
Q
L
I
V
S
N
S
G
K
--
S
G
L
P
I
T
I
-----
K
A
L
N
P
GK
V
F
-
F
T
G
D
A
K
V
E
L
R
G
E
H
L
I
L
E
G
I
W
F
K
D
GNRAIQAWKSHGPGL
V
A
---
I
Y
G
S
Y
N
R
I
T
A
C
V
F
D
--
C
F
D
E
-----
A
N
S
A
Y
I
T
T
S
L
T
----
E
D
-
G
K
V
P
Q
H
C
---
R
I
-
D
H
C
-
S
F
T
DKITFDQV
I
N
L
N
NTARAIKD
G
S
V
-------------
G
G
-----
P
G
M
Y
H
R
V
D
H
C
F
F
S
N
P
--
Q
K
P
G
N
-
A
G
-
G
G
---
I
R
IGYYR
N
--
D
I
G
R
C
L
V
D
-------------
S
N
L
F
M
------
R
Q
D
----------------
S
--------
E
A
E
I
I
T
S
------
K
-----------------------------
S
Q
E
N
V
Y
-------
Y
G
------------
N
T
--
Y
L
N
CQG
T
M
-
N
F
R
H
----
G
D
H
-
Q
V
A
I
N
N
F
Y
I
G
N
D
Q
--------------------------
R
F
------
G
Y
G
G
M
FVWGSRH
V
I
A
C
N
--
Y
F
E
L
SE
T
I
K
S
R
G
N
A
A
L
Y
---
L
N
P
G
A
M
ASEH
A
L
A
F
D
M
----
L
I
A
---
N
N
A
F
---
I
N
V
N
G
Y
A
I
--
H
F
N
-
P
L
D
-------
E
---------
R
R
K
E
Y
C
A
A
N
---------------
R
------------
L
K
F
E
T
P
H
Q
L
-
M
L
K
G
N
L
F
F
K
D
K
P
Y
V
Y
P
F
F
K
--------------
D
-
D
--------
Y
F
IAGK
N
S
W
T
G
N
V
----
A
-
L
G
----------------------
V
E
K
G
I
P
V
N
-
I
S
--
A
N
------
R
S
A
Y
K
P
V
K
I
-
K
D
I
----
Q
P
I
E
----
G
I
A
L
D
L
N
-
A
-
L
I
S
K
GITGKP
L
S
W
D
E
V
R
P
Y
W
-------
L
---
K
E
M
---------------
P
G
T
Y
A
L
T
A
R
L
S
A
D
R
A
A
K
F
K
A
V
I
K
R
N
K
EH----------------------------------------------------------------
30
Fugue
60.68
18%
14
- C7 -
-
4DN7
3
?
A:
[24-428]
-------------
Q
T
E
Q
V
S
L
K
K
R
A
E
S
A
A
E
K
K
A
A
-
F
------
G
----
E
D
F
E
L
E
K
Y
E
E
G
S
K
V
S
K
--
P
------------
I
E
D
L
--
Q
S
-
L
D
-----
E
E
S
K
K
T
L
L
Q
V
G
--
V
I
P
---------------
S
------
E
E
G
R
S
G
S
F
L
V
L
D
--
N
A
V
S
-----
H
S
T
L
K
D
K
N
V
E
L
M
S
T
H
K
A
M
E
K
Y
E
W
L
K
---
D
Y
-
S
W
K
-
L
V
Q
--------------------
V
D
A
-------------
D
---------------
K
Y
T
A
K
T
--
Y
L
E
D
A
-
D
G
-
Y
----
F
I
-----
R
--
V
P
A
G
K
K
T
S
M
------------
P
V
Q
T
C
L
M
L
G
S
K
K
A
A
----------------
Q
--------
T
V
H
N
I
I
I
V
E
EG
A
T
L
-----------------------------
D
I
I
T
G
C
T
T
K
KGVE
E
G
------------
L
H
--
L
G
I
---
S
E
M
Y
I
K
K
G
G
T
L
N
F
T
M
I
H
N
W
A
E
Q
I
G
V
R
P
R
--------------------------
T
V
------
V
-----------
S
V
E
E
G
G
T
Y
V
S
---
N
Y
I
C
L
K
P
V
R
S
V
---
Q
T
Y
P
----------------
T
V
R
LEG
E
G
A
V
---
T
R
L
N
T
I
A
I
--
A
H
P
-
G
S
E
-------
L
---------
D
L
G
S
K
A
I
F
N
---------------
A
------------
P
G
T
R
A
E
L
I
S
-
R
T
I
------
T
I
G
G
R
L
I
A
R
G
--------------
E
M
I
G
NAKG
A
K
G
H
L
----
E
C
K
G
L
V
L
----
T
-
D
K
----------------------
G
S
Q
L
A
I
P
I
-
L
E
--
A
N
VDD
I
E
L
T
H
E
A
A
V
G
K
I
-
A
K
D
----
Q
V
E
Y
L
M
A
R
G
L
T
E
D
E
A
V
G
M
I
I
R
G
------
F
L
D
V
G
I
R
--------------
G
I
P
---------------
E
E
L
K
E
E
I
E
N
T
I
A
Q
T
A
L
G
---------------------------------------------------------------------------
32
Fugue
60.56
14%
-4
- C3 -
-
3WMT
6
FAEB1_ASPOR
A:
[18-522]
------S
F
Q
A
E
C
E
S
F
K
A
K
I
N
V
T
N
A
N
V
H
S
V
T
Y
V
P
-
A
------
G
----
V
N
I
S
M
--
A
D
N
P
S
I
C
G
G
--
D
P
I
T
S
T
F
-----
A
F
C
R
I
--
A
L
-
N
V
-----
T
T
S
S
K
S
Q
I
F
M
E
A
W
L
P
S
---------------
N
Y
SG
R
F
L
S
T
G
N
G
G
L
G
G
C
V
K
--
Y
D
D
M
-----
A
Y
A
A
G
Y
G
F
A
T
V
----
G
T
-
N
N
G
H
F
G
N
NGV
S
F
-
Y
Q
N
-
T
E
V
--------------------
V
E
D
-------------
F
A
-----
Y
R
A
L
H
T
G
V
V
V
G
K
E
L
T
--
K
N
F
Y
P
-
Q
G
-
Y
N
K
S
Y
Y
L
-----
G
C
S
T
G
G
R
Q
G
W
K
-------------
S
V
Q
T
F
------
P
D
D
----------------
F
D
G
V
V
A
G
AP
A
F
N
F
I
N
L
------
T
-----------------------------
S
W
G
A
R
F
-------
L
T
------------
L
T
GD
S
S
A
---
E
T
-
F
V
T
E
----
T
Q
W
-
T
A
V
H
N
E
I
I
R
Q
C
D
S
--------------------------
L
D
------
G
-------------
A
K
D
--
G
I
------
I
E
D
P
D
L
C
Q
P
---
I
I
E
A
LLCNATQSSTSGTCLT
G
A
Q
---
V
K
T
V
---
N
G
V
F
S
A
T
Y
--
G
L
N
-
G
S
F
-------
L
YPRMQPGS
E
L
A
A
Y
S
S
Y
Y
S
---------------
G
------------
T
P
F
A
Y
A
E
D
W
-
Y
R
Y
------
V
V
F
N
N
T
N
W
D
V
--------------
A
-
T
--------
W
T
----
V
Q
D
A
A
I
A
----
N
-
A
Q
DPYQISTWNGDL
S
P
F
Q
K
K
G
G
K
V
L
H
Y
H
G
M
E
D
-
A
I
--
I
S
-------
S
E
S
S
K
V
Y
Y
-
K
H
V
----
A
D
T
M
----
N
L
S
P
S
E
L
-
D
-
S
F
Y
R
------
F
F
P
I
-
S
G
M
A
H
-------
C
---
A
N
A
DGPSAIGQGTGTFAG
N
N
P
Q
D
N
V
L
L
A
M
V
Q
W
V
E
E
G
V
A
P
D
F
V
R
G
A
KLNGSTVE
Y
R
R
K
H
C
KYP
K
R
N
R
Y
V
G
PGSYTDENAWECV----------------------------
29
Fugue
59.46
15%
-39
- C5 -
-
4YUS
1
?
A:
[17-366]
------------
M
K
R
L
T
Y
I
S
K
F
S
R
P
L
S
G
D
E
I
E
A
-
I
------
G
----
R
I
S
S
Q
K
N
Q
---------------------------------
Q
-----
A
N
V
T
G
V
L
L
C
L
D
G
I
F
-----------------
F
Q
---
I
L
E
G
E
A
E
K
I
D
R
I
Y
E
--
R
I
L
A
-----
D
E
R
-
H
T
D
I
L
C
L
----
K
S
-
E
V
E
V
Q
E
R
---
M
F
P
D
W
S
M
Q
T
I
--------------------
N
L
D
-------------
E
N
-----
T
D
F
L
I
R
P
I
K
V
L
L
Q
T
L
--
T
E
S
H
R
-
I
L
-
E
K
---
Y
T
-----
Q
--
P
S
I
F
K
I
I
S
Q
G-----------
T
N
P
L
N
------
I
R
P
----------------
K
--------
A
V
E
K
I
V
F
------
F
-----------------------------
S
D
I
V
S
F
-------
S
T
------------
F
A
--
E
K
L
---
P
V
-
E
E
V
V
----
S
V
V
-
N
S
Y
F
S
V
C
T
A
I
I
T
R
--------------------------
Q
G
------
G
-----------
E
V
T
K
F
--
I
----------
G
D
C
V
M
A
---
Y
F
D
G
----------------
D
C
A
---
D
Q
A
I
---
Q
A
S
L
D
I
L
M
--
E
L
E
-
I
L
R
-------
N
---------
S
-----
A
P
E
---------------
G
------------
S
---------
P
L
R
------
V
L
Y
S
G
I
G
L
A
K
--------------
G
-
K
--------
V
I
----
E
G
N
I
G
S
-----
E
-
L
K
----------------------
R
D
Y
T
I
L
G
D
-
A
V
N
V
A
A
------
R
L
E
A
L
T
R
Q
L
S
Q
A
L
----
V
F
S
S
----
E
V
K
N
S
A
T
-
K
-
S
W
N
F
------
I
W
L
T
D
S
E
L
K
G
KS
E
S
I
D
I
Y
---
S
I
D
---------------
N
E
M
T
R
K
S
S
G
G
L
E
I
A
R
N
I
G
H
Y
L
E
R
V--------------------------------------------------------------------
26
Fugue
59.05
20%
-3
- C6 -
-
5HEA
-
?
A:
[4-295]
---------G
E
L
I
S
I
I
V
P
V
Y
N
---------------------------
V
E
K
Y
L
K
R
C
L
D
S
L
L
R
--
Q
T
----
Y
-----
K
N
F
E
I
--
I
L
-
I
N
-----
D
G
S
T
D
N
-------------------------------
S
S
I
I
C
E
E
Y
A
K
I
D
N
--
R
I
Q
I
-----
L
H
Q
T
N
A
G
P
S
A
A
----
R
N
-
A
G
I
T
Y
A
S
---
G
--
K
Y
I
-
T
F
V
--------------------
D
S
D
-------------
D
F
-----
V
E
E
F
-
Y
L
E
H
L
Y
R
A
L
V
--
D
N
G
S
D
-
I
S
-
V
C
---
N
F
-----
N
--
S
F
N
E
D
R
---------------
Q
S
F
L
F
------
S
I
T
---------------------------
K
E
K
Y
F
------
C
-----------------------------
K
N
Y
T
I
A
-------
E
W
------------
M
D
--
L
N
L
---
F
L
-
T
F
T
-----------------------------------------------------------------------------------------------------------------------------------
F
S
P
T
K
--
L
F
K
-
A
E
L
-------
F
---------
E
G
I
R
F
--
P
L
---------------
G
------------
R
L
R
E
D
D
A
T
I
-
Y
R
L
------
Y
L
K
A
S
Q
I
T
F
I
--------------
N
-
E
--------
G
S
----
Y
Y
Y
S
Q
R
D
----
D
--------------------------------------
I
S
------
S
M
I
S
N
A
E
E
R
-
I
A
L
----
L
A
S
M
----
G
-----
Y
-
D
-
L
T
E
Q
------
I
K
S
Y
K
G
R
L
K
K
-------
C
C
E
D
A
L
R
---------------
N
G
Q
I
E
L
Y
Q
Q
C
C
N
K
L
D
L
I
E
N
Y
P
KE---------------------------------------------------------------------
31
Fugue
57.93
13%
11
* C3 *
-
3IYM
-
?
A:
[39-434]
-------ASA
S
K
A
A
A
F
A
Q
G
G
S
S
D
P
V
P
M
P
G
K
Y
P
V
V
F
------
S
----
T
G
A
G
E
P
T
R
D
Q
E
F
A
L
P
V
--
H
K
A
F
P
L
F
GSVSD
K
Y
R
R
N
--
P
R
-
Y
A
-----
E
F
R
A
H
S
E
F
T
D
G
V
F
--
G
---------------
T
H
---
L
A
V
S
S
L
L
R
L
A
Q
Q
L
V
--
H
A
H
V
-----
N
M
G
L
P
L
G
D
F
A
P
----
L
A
-
S
S
D
V
R
I
P
---
S
A
-
L
A
S
-
V
V
N
--------------------
Q
F
G
-------------
E
F
-----
S
S
P
S
I
G
T
R
F
L
L
R
D
F
E
--
H
A
V
S
R
-
V
V
-
F
L
---
A
D
-----
Q
--
L
W
T
N
G
N
S
H
H
IFA
R
S
W
L
PMSNN
D
G
N
F
K
------
T
I
V
----------------
A
--------
S
R
L
L
E
F
I
------
S
-----------------------------
A
G
D
L
S
I
-------
L
P
------------
T
V
--
L
E
D
---
A
V
-
L
S
G
E
----
V
P
---
E
A
W
E
Q
V
K
D
L
L
G
D
--------------------------
A
P
GVGQVD
R
-----------
R
D
R
F
D
--
F
L
F
---
K
S
Y
A
D
V
G
Q
F
T
T
---
A
F
T
T
----------------
Q
A
A
---
S
D
V
L
---
T
E
L
G
L
P
W
N
----
S
-
P
S
A
-------
G
---------
H
L
N
W
Q
Y
S
T
K
---------------
Q
------------
R
F
T
F
L
A
D
T
W
-
A
K
L
------
S
A
A
Y
S
Q
F
F
E
L
--------------
S
-------------------
S
G
L
A
----
T
-
R
Q
----------------------
S
A
T
G
S
H
A
Q
-
M
V
--
D
L
------
T
S
V
E
G
V
T
V
L
-
K
A
A
----
L
A
L
S
----
A
P
E
F
S
L
A
-
A
-
C
F
P
P
------
S
C
I
F
V
G
G
L
T
R
-------
R
---
V
V
V
---------------
T
T
S
L
S
V
S
Q
R
A
T
E
F
C
Q
M
D
W
R
-------------------------------------------------------------------------
27
Fugue
46.96
12%
8
* C5 *
-
1JVN
-
HIS5_YEAST
A:
[1-555]
-------GSH
M
P
V
V
H
V
I
D
V
E
S
G
N
L
Q
S
L
T
N
A
I
E
H
-
L
------
G
----
Y
E
V
Q
L
V
K
S
P
K
D
F
N
I
S
G
--
T
S
R
L
I
L
P
-----
G
V
G
N
Y
--
G
H
F
V
D
-----
N
L
F
N
R
G
F
E
K
P
I
R
E
Y
I
E
---------------
S
G
---
K
P
I
M
G
I
V
G
L
Q
A
L
F
A
--
G
S
V
E
SPKST
G
L
N
Y
I
D
F
K
L
S
R
----
F
D
-
D
S
E
K
P
V
P
---
E
I
-
G
W
N
-
S
C
I
--------------------
P
S
E
-------------
N
L
FFGLD
P
Y
K
R
Y
Y
F
V
H
S
F
A
A
I
L
N
S
E
K
K
K
N
-
L
E
-
N
D
---
G
W
-----
K
--
I
A
K
A
K
Y
G
S
-------------
E
E
F
I
A
------
A
V
N
K
NN
I
F
A
T
QFHPEKSG
K
A
--------
G
L
N
V
I
E
N
------
F
L
K
QQSPPIPNYS
A
E
E
K
E
L
L
MNDYSNYGLT
R
R
I
I
A
C
-------
L
D
------------
V
R
--
T
N
D
QG-
D
L
-
V
V
T
K
----
G
D
L
-
G
K
P
V
Q
L
A
Q
K
Y
Y
Q
Q
GAD
E
V
T
F
LNITD--------------
C
P
------
L
-----------
K
D
T
P
M
--
L
E
V
---
L
K
Q
A
A
K
T
V
F
V
P
---
L
T
V
G
----------------
G
G
I
---
K
D
I
V
DVD
G
T
K
I
P
A
L
E
--
V
A
S
-
L
Y
F
-------
R
---------
S
G
A
D
K
V
S
I
----------------
G
------------
T
D
A
V
Y
A
A
E
K
-
Y
Y
E
------
L
G
N
R
G
D
G
T
S
P
--------------
I
-
E
--------
T
I
----
S
K
A
Y
G
A
Q
A
V
V
I
S
-
V
D
----------------------
P
K
R
V
Y
V
N
S
-
Q
A
--
D
T
------
K
N
K
V
F
E
T
E
Y
-
P
G
P
NGEK
Y
C
W
Y
----
Q
C
T
I
K
G
G
-
R
-
E
S
R
D
------
L
G
--
V
W
E
L
T
R
-------
A
---
C
E
A
---------------
L
G
A
G
E
I
L
L
N
C
I
D
K
D
G
S
N
S
G
Y
D
L
E
L
I
E
H
V
K
D
A
VK
I
P
V
I
A
S
S
GAGV
P
E
H
F
E
E
A
F
L
KTRAD
A
C
L
G
A
G
M
F
H
R
GEFT
V
N
D
V
K
E
Y
L
L
E
H
G
L
K
V
R
M
D
E
E
24
Fugue
45.94
13%
3
- C6 -
-
3BJE
3
?
A:
[23-349]
-----------
D
L
P
I
G
K
D
G
T
T
L
H
L
K
C
K
S
D
E
L
A
D
-
R
I
I
F
V
GD
P
----
G
R
V
D
V
I
S
G
----
Y
F
D
K
--
D
S
I
R
A
S
R
-----
D
H
R
E
I
--
R
F
-
A
T
-----
G
T
Y
-------
K
G
T
P
V
T
---------------
V
I
---
S
T
G
M
G
V
D
N
I
E
I
V
L
N
--
E
I
H
A
-----
L
K
E
--------------------------
Y
-
D
M
E
-
R
---------------------------------------------
G
Q
W
R
H
R
K
G
D
A
D
A
P
S
A
--
G
P
F
F
D
-
P
S
T
M
K
---
I
I
-----
R
--
L
G
T
C
G
S
P
A
-------------
E
------------
S
----------------
V
--------
P
P
L
A
L
A
V
------
T
-----------------------------
R
H
A
I
G
M
-------
D
N
------------------
T
---
S
L
-
Y
Y
S
A
----
G
T
R
-
E
T
S
K
D
Q
Q
E
I
R
R
I
V
--------------------------
R
E
------
Q
-----------
T
G
L
R
A
--
I
D
I
---
Y
T
S
M
A
H
----------------------------------
P
N
I
T
---
K
S
I
C
A
A
C
D
--
A
H
N
-
A
A
T
-------
G
---------
S
E
A
D
K
Q
Q
Y
V
---------------
I
------------
G
T
T
A
T
A
S
G
F
-
Y
G
C
------
Q
G
R
R
V
G
R
F
M
K
--------------
H
-
L
--------
T
V
----
P
N
M
V
E
E
L
----
G
-
S
L
----------------------
K
F
N
L
S
N
G
V
-
E
V
--
V
T
------
N
I
E
M
E
T
S
A
I
-
C
Y
L
----
S
D
M
L
----
G
Y
-----------
Q
------
A
G
A
A
C
V
V
V
S
K
-------
R
---
V
G
E
---------------
K
K
M
F
L
G
-
D
Q
L
D
A
A
M
K
R
C
I
K
I
I
L
E
A
L
V
S
A----------------------------------------------------------------
25
Fugue
40.88
12%
36
- C6 -
-
1ZQ1
-
GATE_PYRAB
C:
[5-512]
TDKFNYEELG
L
K
V
G
L
E
I
H
R
Q
L
D
T
K
K
L
F
S
P
V
P
S
E
-
L
------
S
DKVE
F
T
F
Q
R
R
L
R
P
T
M
S
E
L
G
E
ID
P
A
A
L
E
E
F
-----
K
K
G
R
V
--
Y
V
-
Y
E
-----
G
N
Y
E
L
T
D
L
V
Y
M
D
E
E
P
P
---------------
R
G
---
P
D
R
E
A
L
E
V
A
L
Q
I
A
Y
LL
N
A
K
P
-----
V
D
E
V
Y
Y
M
R
K
I
V
----
I
D
-
G
S
N
V
S
G
F
---
Q
R
-
T
A
I
-
I
A
T
--------------------
D
G
K
VETPWGAVGIPTI
C
L
-----
E
E
D
A
A
R
I
I
E
R
K
D
K
E
V
--
I
Y
R
L
D
R
L
G
-
I
P
---
L
I
-----
E
--
I
S
T
T
P
D
I
H
H------------
P
E
Q
A
K
------
V
V
A
----------------
K
--------
F
I
G
D
A
L
R
------
A
TKKVKRGLGTIRQ----------------
D
L
N
V
S
I
-------
K
G
GARIEIKGVQEL
D
M
--
I
P
I
---
I
I
-
E
R
E
V
----
E
R
Q
-
L
N
L
L
K
I
R
D
E
L
R
K
R
GVKPKDIKEEFYDVTDIFENTKSKII
A
R
------
V
-----------
I
K
K
G
G
--
K
V
L
---
A
I
K
L
P
K
F
R
G
L
I
GRE
I
Q
P
G
----------------
R
R
L
---
G
T
E
F
---
A
D
R
A
K
K
Y
V
PG
I
F
H
-
I
D
E
LPNYGIS
Q
---------
E
E
V
N
K
V
I
E
R
---------------
L
NLSEEDAFVLVA
A
E
E
E
K
A
K
N
A
-
L
R
E
------
V
I
K
R
A
R
E
A
I
E
GVPEETRRALPDGN
T
-
E
--------
Y
M
----
R
P
L
P
G
K
A
----
R
-
M
Y
----------------------
P
E
T
D
I
P
P
L
R
I
P
--
D
D
------
L
K
K
K
I
K
E
N
L
-
P
E
L
----
P
Q
A
K
----
V
E
R
Y
V
K
E
-
Y
-
K
L
D
R
------
S
L
A
Q
T
L
V
D
D
E
-------
R
---
D
E
L
---------------
F
E
E
L
V
S
M
G
V
K
P
S
L
A
A
S
I
L
V
V
V
LKG--------------------------------------------------------------------
22
HHSearch
39.75
8%
-163
* C4 *
-
2F60
2
K:
[3-28]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-
I
P
--
G
T
------
L
R
F
R
L
S
P
A
A
-
R
N
I
----
L
E
K
H
----
S
L
D
A
S
--------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
33.03
31%
-51
- C4 -
-
3ZM8
-
?
A:
[89-177]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
---
F
P
--
A
G
D
S
F
T
S
---
V
A
A
G
----------------
Q
V
L
---
L
N
A
G
---
Q
N
--
T
I
D
I
--
V
N
N
W
G
W
Y
-------
L
---------
I
D
S
I
T
L
T
P
S
APRPPHDINPNLNNP
N
------------
A
D
T
N
A
K
K
L
Y
S
Y
L
R
------
S
V
Y
G
N
K
I
I
S
G
--------------
Q
-
Q
--------
E
L
----
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
32.00
18%
-27
- C4 -
-
1DJ8
-
HDEA_ECOLI
F:
[30-86]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-
T
--------
A
V
----
G
F
A
E
A
L
N
----
N
K
D
K
----------------------
P
E
---
D
A
V
-
L
D
--
V
Q
------
G
I
A
T
V
T
P
A
I
-
V
Q
A
----
C
T
Q
D
----
K
----
Q
A
-
N
-
F
K
D
K
------
V
K
G
E
W
D
K
I
K
--------------------------------------------------------------------------------------------------------------------------
17
HHSearch
30.52
22%
-7
- C4 -
-
2K6O
-
A:
[10-27]
------------------------------
K
E
K
-
I
------
G
----
K
E
F
K
R
I
V
Q
R
I
K
D
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
28.08
50%
-
- C1 -
-
4BHR
-
?
B:
[81-88]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
Q
F
----
S
-
F
Q
----------------------
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
26.53
24%
33
- C4 -
-
5FCM
2
?
C:
[8-28]
-----------------------------------------
D
----
R
T
L
A
V
L
R
R
K
L
E
A
-
L
G
Y
--
S
D
P
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_CBE
26.25
35%
1
- C4 -
-
5JBE
1
?
B:
[587-642]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
---
V
P
V
I
S
G
D
Q
D
V
T
---
T
N
A
S
----------------
D
V
V
---
A
N
K
E
---
K
T
F
E
S
N
A
A
--
L
D
S
-
H
M
I
-------
Y
---------
E
D
F
S
L
F
Q
P
E
---------------
P
------------
T
S
V
E
N
H
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
26.17
35%
2
- C4 -
-
5JBE
-
?
A:
[587-642]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
---
V
P
V
I
S
G
D
Q
D
V
T
---
T
N
A
S
----------------
D
V
V
---
A
N
K
E
---
K
T
F
E
S
N
A
A
--
L
D
S
-
H
M
I
-------
Y
---------
E
D
F
S
L
F
Q
P
E
---------------
P
------------
T
S
V
E
N
H
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
25.59
35%
12
- C4 -
-
5JBD
-
?
A:
[615-670]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
---
V
P
V
I
S
G
D
Q
D
V
T
---
T
N
A
S
----------------
D
V
V
---
A
N
K
E
---
K
T
F
E
S
N
A
A
--
L
D
S
-
H
M
I
-------
Y
---------
E
D
F
S
L
F
Q
P
E
---------------
P
------------
T
S
V
E
N
H
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
24.64
50%
-
- C2 -
-
4BHR
-
?
A:
[81-88]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
Q
F
----
S
-
F
Q
----------------------
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
24.55
35%
15
- C4 -
-
5JBF
2
?
A:
[587-642]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
---
V
P
V
I
S
G
D
Q
D
V
T
---
T
N
A
S
----------------
D
V
V
---
A
N
K
E
---
K
T
F
E
S
N
A
A
--
L
D
S
-
H
M
I
-------
Y
---------
E
D
F
S
L
F
Q
P
E
---------------
P
------------
T
S
V
E
N
H
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------