@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VN39: (2017-11-12 )
MCNKASSDLTDYVIRQLGRTKNKRYEAYVVSRIIHLLNDFTLKFVTQQFVRLSNKKIALTDLYFPQLGIHIEVDEGHHFLRNSKMEYSLNQIDEPLYSISQTESDAMREEDIISITGHKIFRVNVFKNQEGQPQNLENIHQQIDKIIEEIKTAKNKLIEASTFKEWNIETEYNPQTYIDLGRISLADNVVLKTTKDVCNCFGYSYKNYQRGGALHPYKKDTLIWFPRLYENKDWINTISPDGLTITEKSTDETITLKKLEEWKNGPQKRIVFARVKDNLSSRAMYRFMGLYEFQKADLKDGAVWKRVKCEVQTYSPKETKC
Atome Classification :
(20 SA)
---------------....-...-..10......--..20.....-...30.------------.......40--..-...-....50..--..--..-..60....--....70......---..80...---..--...-90......--.------.100.......110........120----...------..------...130.......140..----.....--------------------------------150.......160--......-----..170...----....-----180.-.----------------.....190.......200....-.-..210--------...--------...--------.220-.......-----230.----------.....--.240.--------------------------......250.......-------260------....-...270-.....--..280.......-------290...-..-..----------------300-....--...310.......320--------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------MCNK-ASS-
D
L
T
D
Y
V
I
R
Q
L--GRTKNK
R
Y
E
-
A
Y
V
V
S
R
------------
I
I
H
L
L
N
D
F
---
T
L
-
K
F
V
-
T
Q
Q
F
V
R
LS--N
K
--
K
I
-
A
L
T
D
LYFP--QL
G
I
H
I
E
VDEGH---
H
F
L
R
NSK---
M
E
--
Y
S
L
-
N
Q
ID
E
P
L
Y
--
S
------ISQTE
S
D
AMREE-
D
I
I
S
ITG
H
K
I
F
-----
R
V
N
------
V
F
------KNQEGQPQ
N
L
E
N
I
H
Q
Q
I
D
----
K
I
I
E
E
--------------------------------
I
K
T
A
K
N
KLIEA-S--TFKEW
N
-----
I
E
TEYNPQ----
T
Y
I
D
-----LG
R
I
-S----------------LAD
N
V
V
L
K
T
T
K
D
V
C
N
C
FGYSYK-N-YQRGG--------ALH--------PYK--------KD
T
L
-
I
WF
P
R
LY-----ENKD----------WINTI--SPD
G
L
--------------------------
T
I
TEKSTDET
I
T
L
K
K
L
-------
E
E
W
------KNGP-Q
K
R
I
V
F
-
A
R
V
KD--N
L
S
S
R
A
M
Y
R
F
M
G
-------
L
Y
E
F
Q
K-AD-LK----------------DG
A
-
V
W
K
R
--
V
K
C
E
V
Q
TYSPKETKC---------------------------------------------------------------------------------------
2
PsiBlast_PDB
85.77
99%
-
- C6 -
-
4PBA
-
?
B:
[5-317]
--------------------
A
S
S
-
D
L
T
D
Y
V
I
R
Q
L
--
G
R
T
K
N
K
R
Y
E
-
A
Y
V
V
S
R
------------
I
I
H
L
L
N
D
F
---
T
L
-
K
F
V
-
T
Q
Q
F
V
R
L
S
--
N
K
--
K
I
-
A
L
T
D
L
Y
F
P
--
Q
L
G
I
H
I
E
V
D
E
G
H
---
H
F
L
R
N
S
K
---
M
E
--
Y
S
L
-
N
Q
I
D
E
P
L
Y
--
S
------
I
S
Q
T
E
S
D
A
M
R
E
E
-
D
I
I
S
I
T
G
H
K
I
F
-----
R
V
N
------
V
F
------
K
N
Q
E
G
Q
P
Q
N
L
E
N
I
H
Q
Q
I
D
----
K
I
I
E
E
--------------------------------
I
K
T
A
K
N
K
L
I
E
A
-
S
--
T
F
K
E
W
N
-----
I
E
T
E
Y
N
P
Q
----
T
Y
I
D
-----
L
G
R
I
-
S
----------------
L
A
D
N
V
V
L
K
T
T
K
D
V
C
N
C
F
G
Y
S
Y
K
-
N
-
Y
Q
R
G
G
--------
A
L
H
--------
P
Y
K
--------
K
D
T
L
-
I
W
F
P
R
L
Y
-----
E
N
K
D
----------
W
I
N
T
I
--
S
P
D
G
L
--------------------------
T
I
T
E
K
S
T
D
E
T
I
T
L
K
K
L
-------
E
E
W
------
K
N
G
P
-
Q
K
R
I
V
F
-
A
R
V
K
D
--
N
L
S
S
R
A
M
Y
R
F
M
G
-------
L
Y
E
F
Q
K
-
A
D
-
L
K
----------------
D
G
A
-
V
W
K
R
--
V
K
S
E
V
Q
T
Y
S
P
K
-------------------------------------------------------------------------------------------
22
HHSearch
83.18
99%
-73
- C6 -
-
4PAR
1
?
C:
[4-317]
------------------
K
-
A
S
S
-
D
L
T
D
Y
V
I
R
Q
L
--
G
R
T
K
N
K
R
Y
E
-
A
Y
V
V
S
R
------------
I
I
H
L
L
N
D
F
---
T
L
-
K
F
V
-
T
Q
Q
F
V
R
L
S
--
N
K
--
K
I
-
A
L
T
D
L
Y
F
P
--
Q
L
G
I
H
I
E
V
D
E
G
H
---
H
F
L
R
N
S
K
---
M
E
--
Y
S
L
-
N
Q
I
D
E
P
L
Y
--
S
------
I
S
Q
T
E
S
D
A
M
R
E
E
-
D
I
I
S
I
T
G
H
K
I
F
-----
R
V
N
------
V
F
------
K
N
Q
E
G
Q
P
Q
N
L
E
N
I
H
Q
Q
I
D
----
K
I
I
E
E
--------------------------------
I
K
T
A
K
N
K
L
I
E
A
-
S
--
T
F
K
E
W
N
-----
I
E
T
E
Y
N
P
Q
----
T
Y
I
D
-----
L
G
R
I
-
S
----------------
L
A
D
N
V
V
L
K
T
T
K
D
V
C
N
C
F
G
Y
S
Y
K
-
N
-
Y
Q
R
G
G
--------
A
L
H
--------
P
Y
K
--------
K
D
T
L
-
I
W
F
P
R
L
Y
-----
E
N
K
D
----------
W
I
N
T
I
--
S
P
D
G
L
--------------------------
T
I
T
E
K
S
T
D
E
T
I
T
L
K
K
L
-------
E
E
W
------
K
N
G
P
-
Q
K
R
I
V
F
-
A
R
V
K
D
--
N
L
S
S
R
A
M
Y
R
F
M
G
-------
L
Y
E
F
Q
K
-
A
D
-
L
K
----------------
D
G
A
-
V
W
K
R
--
V
K
S
E
V
Q
T
Y
S
P
K
-------------------------------------------------------------------------------------------
11
PsiBlast_CBE
83.18
99%
-73
- C6 -
-
4PAR
1
?
C:
[4-317]
------------------
K
-
A
S
S
-
D
L
T
D
Y
V
I
R
Q
L
--
G
R
T
K
N
K
R
Y
E
-
A
Y
V
V
S
R
------------
I
I
H
L
L
N
D
F
---
T
L
-
K
F
V
-
T
Q
Q
F
V
R
L
S
--
N
K
--
K
I
-
A
L
T
D
L
Y
F
P
--
Q
L
G
I
H
I
E
V
D
E
G
H
---
H
F
L
R
N
S
K
---
M
E
--
Y
S
L
-
N
Q
I
D
E
P
L
Y
--
S
------
I
S
Q
T
E
S
D
A
M
R
E
E
-
D
I
I
S
I
T
G
H
K
I
F
-----
R
V
N
------
V
F
------
K
N
Q
E
G
Q
P
Q
N
L
E
N
I
H
Q
Q
I
D
----
K
I
I
E
E
--------------------------------
I
K
T
A
K
N
K
L
I
E
A
-
S
--
T
F
K
E
W
N
-----
I
E
T
E
Y
N
P
Q
----
T
Y
I
D
-----
L
G
R
I
-
S
----------------
L
A
D
N
V
V
L
K
T
T
K
D
V
C
N
C
F
G
Y
S
Y
K
-
N
-
Y
Q
R
G
G
--------
A
L
H
--------
P
Y
K
--------
K
D
T
L
-
I
W
F
P
R
L
Y
-----
E
N
K
D
----------
W
I
N
T
I
--
S
P
D
G
L
--------------------------
T
I
T
E
K
S
T
D
E
T
I
T
L
K
K
L
-------
E
E
W
------
K
N
G
P
-
Q
K
R
I
V
F
-
A
R
V
K
D
--
N
L
S
S
R
A
M
Y
R
F
M
G
-------
L
Y
E
F
Q
K
-
A
D
-
L
K
----------------
D
G
A
-
V
W
K
R
--
V
K
S
E
V
Q
T
Y
S
P
K
-------------------------------------------------------------------------------------------
3
PsiBlast_PDB
82.63
99%
-68
- C6 -
-
4PBB
-
?
A:
[5-318]
--------------------
A
S
S
-
D
L
T
D
Y
V
I
R
Q
L
--
G
R
T
K
N
K
R
Y
E
-
A
Y
V
V
S
R
------------
I
I
H
L
L
N
D
F
---
T
L
-
K
F
V
-
T
Q
Q
F
V
R
L
S
--
N
K
--
K
I
-
A
L
T
D
L
Y
F
P
--
Q
L
G
I
H
I
E
V
D
E
G
H
---
H
F
L
R
N
S
K
---
M
E
--
Y
S
L
-
N
Q
I
D
E
P
L
Y
--
S
------
I
S
Q
T
E
S
D
A
M
R
E
E
-
D
I
I
S
I
T
G
H
K
I
F
-----
R
V
N
------
V
F
------
K
N
Q
E
G
Q
P
Q
N
L
E
N
I
H
Q
Q
I
D
----
K
I
I
E
E
--------------------------------
I
K
T
A
K
N
K
L
I
E
A
-
S
--
T
F
K
E
W
N
-----
I
E
T
E
Y
N
P
Q
----
T
Y
I
D
-----
L
G
R
I
-
S
----------------
L
A
D
N
V
V
L
K
T
T
K
D
V
C
N
C
F
G
Y
S
Y
K
-
N
-
Y
Q
R
G
G
--------
A
L
H
--------
P
Y
K
--------
K
D
T
L
-
I
W
F
P
R
L
Y
-----
E
N
K
D
----------
W
I
N
T
I
--
S
P
D
G
L
--------------------------
T
I
T
E
K
S
T
D
E
T
I
T
L
K
K
L
-------
E
E
W
------
K
N
G
P
-
Q
K
R
I
V
F
-
A
R
V
K
D
--
N
L
S
S
R
A
M
Y
R
F
M
G
-------
L
Y
E
F
Q
K
-
A
D
-
L
K
----------------
D
G
A
-
V
W
K
R
--
V
K
S
E
V
Q
T
Y
S
P
K
E
------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.62
99%
-63
- C6 -
-
4PAR
-
?
B:
[5-317]
--------------------
A
S
S
-
D
L
T
D
Y
V
I
R
Q
L
--
G
R
T
K
N
K
R
Y
E
-
A
Y
V
V
S
R
------------
I
I
H
L
L
N
D
F
---
T
L
-
K
F
V
-
T
Q
Q
F
V
R
L
S
--
N
K
--
K
I
-
A
L
T
D
L
Y
F
P
--
Q
L
G
I
H
I
E
V
D
E
G
H
---
H
F
L
R
N
S
K
---
M
E
--
Y
S
L
-
N
Q
I
D
E
P
L
Y
--
S
------
I
S
Q
T
E
S
D
A
M
R
E
E
-
D
I
I
S
I
T
G
H
K
I
F
-----
R
V
N
------
V
F
------
K
N
Q
E
G
Q
P
Q
N
L
E
N
I
H
Q
Q
I
D
----
K
I
I
E
E
--------------------------------
I
K
T
A
K
N
K
L
I
E
A
-
S
--
T
F
K
E
W
N
-----
I
E
T
E
Y
N
P
Q
----
T
Y
I
D
-----
L
G
R
I
-
S
----------------
L
A
D
N
V
V
L
K
T
T
K
D
V
C
N
C
F
G
Y
S
Y
K
-
N
-
Y
Q
R
G
G
--------
A
L
H
--------
P
Y
K
--------
K
D
T
L
-
I
W
F
P
R
L
Y
-----
E
N
K
D
----------
W
I
N
T
I
--
S
P
D
G
L
--------------------------
T
I
T
E
K
S
T
D
E
T
I
T
L
K
K
L
-------
E
E
W
------
K
N
G
P
-
Q
K
R
I
V
F
-
A
R
V
K
D
--
N
L
S
S
R
A
M
Y
R
F
M
G
-------
L
Y
E
F
Q
K
-
A
D
-
L
K
----------------
D
G
A
-
V
W
K
R
--
V
K
S
E
V
Q
T
Y
S
P
K
-------------------------------------------------------------------------------------------
5
PsiBlast_PDB
55.99
30%
26
- C6 -
-
4OQ2
1
?
A:
[14-299]
--------------------------
T
D
Y
I
L
R
A
L
--
S
K
I
S
H
K
R
W
E
-
H
Y
I
I
N
R
------------
V
V
H
T
L
D
D
P
---
D
I
-
E
F
V
-
C
Q
Q
C
I
R
K
E
--
G
H
LG
K
I
-
Y
L
A
D
L
L
F
P
--
Q
L
N
L
Y
L
E
I
D
E
A
H
---
H
D
S
N
D
A
R
--------------------------------
K
A
D
A
V
R
R
L
-
D
I
V
E
A
T
G
F
Q
E
E
-----
R
I
------------------
P
A
S
N
I
T
L
S
E
V
N
K
L
V
D
----
E
F
V
R
L
--------------------------------
V
K
D
K
K
E
E
L
E
N
Q
-
G
--
L
F
F
R
W
D
-----
Y
D
E
R
Y
S
A
K
----
K
H
I
N
-----
T
G
Y
M
-
A
----------------
V
G
P
N
S
V
F
R
Y
H
R
D
A
L
Q
C
F
G
Y
R
R
E
G
H
-
H
Q
S
G
G
--------
W
A
L
--------
P
A
E
V
A
Q
S
I
GLT
G
R
V
M
-
V
W
F
P
R
L
Y
-----
E
A
G
E
----------
W
K
N
A
L
--
S
A
D
G
N
--------------------------
K
I
T
E
Q
S
L
N
A
T
R
N
Y
Q
---------
E
T
W
-----------
D
Y
R
I
V
M
-
A
H
S
R
D
--
E
L
-
N
R
T
L
Y
R
F
L
G
-------
V
F
A
I
D
V
-
D
K
-
S
S
----------------
D
E
V
K
V
F
S
R
--
V
Y
S
R
V
N
V
Y
----------------------------------------------------------------------------------------------
23
HHSearch
54.57
33%
26
- C6 -
-
4OQ2
1
?
A:
[8-300]
------------------
H
-
E
F
M
-
S
K
T
D
Y
I
L
R
A
L
--
S
K
I
S
H
K
R
W
E
-
H
Y
I
I
N
R
------------
V
V
H
T
L
D
D
P
---
D
I
-
E
F
V
-
C
Q
Q
C
I
R
K
E
GH
L
G
--
K
I
-
Y
L
A
D
L
L
F
P
--
Q
L
N
L
Y
L
E
I
D
E
A
H
---
H
D
S
N
D
A
--------------------------------
R
K
A
D
A
V
R
R
L
-
D
I
V
E
A
T
G
F
Q
E
E
-----
R
I
P
------
A
S
------
N
------
I
T
L
S
E
V
N
K
L
V
D
----
E
F
V
R
L
--------------------------------
V
K
D
K
K
E
E
L
E
N
Q
-
G
--
L
F
F
R
W
D
-----
Y
D
E
R
Y
S
A
K
----
K
H
I
N
-----
T
G
Y
M
-
A
----------------
V
G
P
N
S
V
F
R
Y
H
R
D
A
L
Q
C
F
G
Y
R
R
E
-
G
H
H
Q
S
G
G
--------
W
A
L
P
A
E
V
A
Q
S
I
G
L
T
--------
G
R
V
M
-
V
W
F
P
R
L
Y
-----
E
A
G
E
----------
W
K
N
A
L
--
S
A
D
G
N
--------------------------
K
I
T
E
Q
S
L
N
A
T
R
-------------
N
Y
------
Q
E
T
W
-
D
Y
R
I
V
M
-
A
H
S
R
D
--
E
L
N
-
R
T
L
Y
R
F
L
G
-------
V
F
A
I
D
V
D
K
S
-
S
D
----------------
E
V
K
-
V
F
S
R
--
V
Y
S
R
V
N
V
Y
R
---------------------------------------------------------------------------------------------
4
PsiBlast_PDB
53.33
30%
20
- C6 -
-
4OKY
-
?
C:
[4-289]
--------------------------
T
D
Y
I
L
R
A
L
--
S
K
I
S
H
K
R
W
E
-
H
Y
I
I
N
R
------------
V
V
H
T
L
D
D
P
---
D
I
-
E
F
V
-
C
Q
Q
C
I
R
K
E
--
G
H
LG
K
I
-
Y
L
A
D
L
L
F
P
--
Q
L
N
L
Y
L
E
I
D
---------
N
D
A
R
--------------------------------
K
A
D
A
V
R
R
L
-
D
I
V
E
A
T
G
F
Q
E
E
-----
R
I
------------------
P
A
S
N
I
T
L
S
E
V
N
K
L
V
D
----
E
F
V
R
L
--------------------------------
V
K
D
K
K
E
E
L
E
N
Q
-
G
--
L
F
F
R
W
D
-----
Y
D
E
R
Y
S
A
K
----
K
H
I
N
-----
T
G
Y
M
-
A
----------------
V
G
P
N
S
V
F
R
Y
H
R
D
A
L
Q
C
F
G
Y
R
R
-----
Q
S
G
G
--------
W
A
L
--------
P
A
E
VAQSIGLT
G
R
V
M
-
V
W
F
P
R
L
Y
-----
E
A
G
E
----------
W
K
N
A
L
--
S
A
D
G
N
--------------------------
K
I
T
E
Q
S
L
N
A
T
R
N
Y
Q
---------
E
T
W
-----------
D
Y
R
I
V
M
-
A
H
S
R
D
--
E
L
-
N
R
T
L
Y
R
F
L
G
-------
V
F
A
I
D
V
-
D
K
-
S
S
----------------
D
E
V
K
V
F
S
R
--
V
Y
S
R
V
N
V
Y
----------------------------------------------------------------------------------------------
12
Fugue
52.82
31%
26
- C6 -
-
4OQ2
1
?
A:
[4-300]
---------------
H
H
H
H
-
H
E
F
M
S
K
T
D
Y
I
L
R
A
L
--
S
K
I
S
H
K
R
W
E
-
H
Y
I
I
N
R
------------
V
V
H
T
L
D
D
P
---
D
I
-
E
F
V
-
C
Q
Q
C
I
R
K
E
--
G
H
LG
K
I
-
Y
L
A
D
L
L
F
P
--
Q
L
N
L
Y
L
E
I
D
E
A
H
---
H
------------------------
D
--
S
------
N
D
A
R
K
A
D
A
V
R
R
L
-
D
I
V
E
A
T
G
F
Q
E
E
-----
R
I
P
------
A
------------
S
N
I
T
L
S
E
V
N
K
L
V
D
----
E
F
V
R
L
--------------------------------
V
K
D
K
K
E
E
L
E
N
Q
-
G
--
L
F
F
R
W
D
-----
Y
D
E
R
Y
S
A
K
----
K
H
I
N
-----
T
G
-
Y
M
A
----------------
V
G
P
N
S
V
F
R
Y
H
R
D
A
L
Q
C
F
G
Y
R
R
E
-
G
-
H
H
Q
S
G
G
W
A
L
P
A
E
V
A
Q
S
--------
I
G
L
--------
T
G
R
V
M
V
W
F
P
R
L
Y
-----
E
A
G
E
----------
W
K
N
A
L
--
S
A
D
G
N
--------------------------
K
I
T
E
Q
S
L
N
A
T
R
N
Y
Q
E
--------------------
T
-
W
D
Y
R
I
V
M
A
H
S
R
D
--
E
L
N
-
R
T
L
Y
R
F
L
G
-------
V
F
A
I
D
V
-
D
K
S
S
D
----------------
E
V
K
-
V
F
S
R
--
V
Y
S
R
V
N
V
Y
R
---------------------------------------------------------------------------------------------
39
HHSearch
38.80
17%
-420
- C6 -
-
1UJ6
-
RPIA_THET2
A:
[168-185]
-------------------------------------------------------------------------------------
F
Y
F
T
D
--
G
G
--
H
--
L
I
A
D
C
R
F
G
--
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
36.69
17%
-381
- C6 -
-
1UJ5
-
RPIA_THET2
A:
[168-185]
-------------------------------------------------------------------------------------
F
Y
F
T
D
--
G
G
--
H
--
L
I
A
D
C
R
F
G
--
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
30.26
22%
-13
- C6 -
-
3HRL
-
?
A:
[10-100]
---------------------------------------------------
K
------------
L
W
Q
H
L
R
A
G
RLN
G
Y
-
K
F
R
-
R
Q
Q
P
M
------
G
--
N
--
Y
I
V
D
F
M
C
V
--
T
P
K
L
I
V
E
A
D
G
--------------------------------------------
V
Y
D
H
A
R
T
V
-
Y
-
L
N
S
L
G
F
T
V
L
-----
R
F
W
------
N
-----------------
H
E
I
L
Q
Q
T
N
----
D
V
L
A
E
--------------------------------
I
L
R
V
L
Q
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
28.25
15%
-52
- C6 -
-
1VSR
-
VSR_ECOLI
A:
[7-122]
---------------------------------------------------
R
------------
L
A
S
L
L
T
G
Q
---
G
L
-
A
F
R
-
V
Q
D
A
S
------
L
--
P
--
G
R
P
D
F
V
V
D
--
E
Y
R
C
V
I
F
T
H
G
C
F
W--
H
H
H
H
C
Y
L
-------------
F
K
V
P
A
T
R
T
E
F
W
L
E
K
I
G
K
N
V
E
R
D
R
R
D
I
S
-
R
-
L
Q
E
L
G
W
R
V
L
-----
I
V
W
------
E
-----------------
C
A
L
R
G
R
E
K
LT
D
E
A
L
T
E
R
--------------------------------
L
E
E
W
I
C
G
E
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
26.91
14%
-49
- C6 -
-
1CW0
3
VSR_ECOLI
A:
[23-140]
------------------------------------------------
I
E
K
R
------------
L
A
S
L
L
T
G
Q
---
G
L
-
A
F
R
-
V
Q
D
A
S
------
L
--
P
--
G
R
P
D
F
V
V
D
--
E
Y
R
C
V
I
F
T
H
G
C
F
W--
H
H
H
H
C
Y
L
FKV
P
A
--
T
R
T
-
E
F
W
L
E
--
K
--
I
------
G
K
N
V
E
R
D
R
R
D
I
S
-
R
-
L
Q
E
L
G
W
R
V
L
-----
I
V
W
------
E
-----------------
C
A
L
R
G
R
E
K
LT
D
E
A
L
T
E
R
--------------------------------
L
E
E
W
I
C
G
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
26.52
17%
43
- C3 -
-
5MSX
4
?
A:
[21-459]
---------------
H
N
N
P
F
G
N
A
-
L
I
P
D
M
I
A
D
A
S
--
I
Q
E
I
N
G
V
F
Y
-
C
Y
A
T
T
D
GYGQGLKTSG
P
P
V
V
W
K
S
K
D
F
---
V
H
W
S
F
D
-
G
T
Y
F
P
S
A
A
--
K
E
--
K
Y
W
A
P
S
K
A
I
F
A
NG
K
Y
Y
I
Y
P
T
I
N
G
Y
M
---
Y
P
A
V
A
D
K
---
P
E
GP
F
K
L
-
A
R
G
K
D
E
F
Y
--
K
-------
P
F
T
P
S
T
L
L
Q
S
K
-
N
P
G
G
I
-
D
A
E
I
F
V
D
DDG
Q
A
Y
------
V
F
------
W
G
R
-
R
H
V
A
K
L
N
E
D
M
I
T
V
D
----
S
V
V
Q
V
--------------------------------
I
S
T
P
R
K
E
Y
S
E
G
-
P
--
I
F
F
K
R
K
G
I
Y
Y
Y
L
Y
T
I
G
G
D
E
K
Y
Q
Y
A
Y
V
M
S
RVSP
M
G
P
F
-
E
----------------
A
P
E
Q
D
I
I
S
T
T
N
Y
E
R
G
I
F
G
P
-------
G
H
G
C
--------
V
F
H
--------
P
E
G
--------
T
D
N
Y
-
Y
F
A
Y
L
E
F
GRRST
N
R
Q
T
----------
Y
V
N
Q
L
K
F
N
E
D
G
T
IRPVELTMDGVGAL
K
K
V
K
S
D
K
K
M
K
I
D
T
V
Y
A
S
S
I
E
V
P
L
K
I
E
P
M
KDPTC
L
R
T
E
Y
FV
P
S
F
A
V
D
G
A
-
N
G
S
R
W
M
-
A
A
A
E
D
--
S
I
N
P
W
I
V
A
D
L
G
T
-------
V
K
K
V
R
R
-
S
E
-
I
Y
FVRPTA
G
H
A
Y
V
I
E
A
S
M
D
G
K
-
V
W
Q
E
FA
V
H
Q
D
R
K
M
C
S
P
H
T
D
V
L
NKRFR
Y
L
R
I
K
I
LKGVPGIW
E
W
N
I
Y---------------------------------------------------------------
35
HHSearch
25.39
15%
-172
- C6 -
-
4M8L
1
RPIA_FRATW
A:
[149-181]
----------------------------------------------------------------
I
A
R
Q
I
V
K
L
---
G
G
-
Q
P
V
-
Y
R
E
Q
T
I
T
D
--
N
G
--
N
--
V
I
L
D
V
Y
N
L
--
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
25.20
19%
36
- C5 -
-
3DU1
-
?
X:
[0-236]
---------------------
H
M
-
N
V
G
E
I
L
R
H
Y
A
--
A
G
K
R
N
---------------------------
F
Q
H
I
---
N
L
-
Q
E
I
-
E
L
T
N
A
S
L
T
--
G
A
--
D
L
-
S
Y
A
D
L
R
Q
T
--
R
L
G
---
K
S
N
F
S
H
---
T
C
L
R
E
A
D
---
L
---------
S
E
A
I
L
W
--
G
------
I
D
L
S
E
A
D
L
Y
R
A
I
L
R
E
A
D
L
T
G
A
K
L
V
-----
K
T
R
------
L
---------------------
E
E
A
N
----
L
I
K
A
S
--------------------------------
L
C
G
A
N
L
N
S
A
N
L
-
S
--
R
C
L
L
F
Q
-----
A
D
L
R
P
S
S
N
----
Q
R
T
D
-----
L
G
Y
V
-
L
----------------
L
T
G
-------------
A
D
L
S
Y
A
-
D
-
L
-
R
A
A
--------
S
L
H
--------
H
A
N
--------
L
D
G
A
-
K
L
C
----------
R
A
N
----------
F
G
R
T
I
--
Q
W
G
N
L
--------------------------
A
A
D
L
S
G
A
----
S
L
Q
G
A
-------
D
----------------
L
S
Y
-
A
N
L
E
S
--
A
I
L
R
K
A
---------------
N
L
Q
G
-
A
D
-
L
T
-----------------
G
A
-
I
L
K
D
--
A
E
L
K
-
G
A
I
M
P
D
G
S
I
H
---------------------------------------------------------------------------------------
6
PsiBlast_PDB
24.72
36%
-47
- C1 -
-
3Q5I
-
?
A:
[378-421]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
G
Y
N
V
L
-----
R
N
--------
F
------
K
--
L
G
E
---
L
K
N
V
E
E
E
V
D
----
N
I
L
K
E
--------------------------------
V
D
F
D
K
N
G
Y
I
E
Y
-
S
--
E
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
23.89
16%
65
- C6 -
-
2BMF
-
?
A:
[169-618]
--------------M
A
S
I
E
-
D
N
P
-
E
I
E
D
D
I
F
R
K
K
--
R
L
T
I
M
D
L
H
P
G
A
G
K
T
K
R
------------
Y
L
P
A
I
V
R
E
---
A
I
-
K
R
G
-
L
R
T
L
I
-
L
A
--
P
T
--
R
V
-
V
A
A
E
M
E
E
A
--
L
R
G
L
P
I
R
Y
Q
T
G
R
EI
V
D
L
M
C
H
A
T
---
F
T
--
M
R
L
L
S
P
I
R
V
P
N
Y
--
N
------
L
I
I
M
D
E
A
H
F
T
D
P
-
A
S
I
A
A
R
G
Y
I
S
T
-----
R
V
E
M
GE
A
A
G
I
F
M
T
ATPP
G
S
R
D
P
F
P
Q
S
N
A
P
I
M
D
E
E
R
----
E
I
P
E
R
SWN
S
G
H
E
WVTDFKGK
T
V
W
F
V
P
S
I
K
A
G
N
D
I
A
A
C
L
R
K
N
G
K
K
V
I
Q
L
-
S
RK
T
F
D
S
E
Y
-----
I
K
T
R
T
N
D
W
----
D
F
V
V
-----
T
T
D
I
-
S
EMGANFKAE
R
V
I
D
PR
R
C
M
K
P
V
I
L
T
D
G
E
E
R
V
I
L
A
G
P
M
P
V
-
T
-
H
S
S
A
A
--------
Q
R
R
G
RVGRNP-
K
N
E
--------
N
D
Q
Y
-
I
Y
M
G
E
P
L
-----
E
N
D
E
DCA
H
W
K
E
A
K
M
L
L
D
N
I
N-
T
P
E
G
I
--------------------------
I
P
S
M
F
E
P
E
R
E
K
V
D
A
I
D
-------
G
E
Y
------
R
L
R
G
-
E
A
R
K
T
F
-
V
D
L
M
R
RG
D
L
P
V
W
L
A
Y
R
V
A
A
E
GINYAD
R
R
W
C
F
D
-
G
V
-
K
N
----------------
N
Q
I
-
L
E
E
N
--
V
E
V
E
I
W
T
K
E
G
E
R
K
K
L
KPRWLDARIYSD
P
L
A
L
K
E
F
K
E
F
A
A
GRK------------------------------------------------------------
19
Fugue
22.49
15%
-21
- C6 -
-
5AYN
9
?
A:
[7-426]
LR
I
E
T
Q
L
L
L
G
R
L
L
T
R
S
G
D
Q
-
A
W
D
-
F
V
V
P
F
A
L
L
V
I
F
P
G
K
L
Q
V
A
A
F
Y
-
Y
L
I
V
K
I
------------
G
T
F
L
L
T
P
S
---
S
G
-
K
W
I
D
T
H
P
R
I
Q
V
V
--
K
W
--
G
V
-
W
L
Q
F
F
A
I
L
--
A
G
M
V
F
F
G
M
L
D
G
L
---
V
R
-
A
G
G
R
---
E
S
--
W
L
L
-
S
V
L
F
I
A
L
A
--
L
------
S
G
V
M
A
S
L
G
S
Q
I
T
-
D
I
S
V
G
N
D
-------------------
L
------
A
P
S
L
V
A
P
E
K
L
T
H
F
N
S
W
L
R
----
R
I
D
L
A
--------------------------------
T
E
V
G
A
P
I
L
A
G
A
L
F
--
P
L
A
G
L
F
-----
L
I
G
L
W
N
L
V
----
S
F
V
P
-------
E
Y
-
F
----------------
L
L
R
N
V
I
Q
R
S
--------
G
L
K
I
K
-
V
-
L
T
E
A
I
--------
N
L
R
--------
G
S
F
--------
S
D
P
I
-
F
W
L
I
L
S
Y
-----
A
-
L
L
----------
W
L
S
V
L
--
S
P
H
G
V
--------------------------
L
L
A
A
Y
L
K
D
E
----
M
R
L
-------
P
E
T
------
E
I
G
L
F
R
G
L
G
A
V
-
F
G
L
I
S
--
T
V
S
F
P
Y
L
V
R
R
L
G
-------
L
I
S
S
S
R
-
W
H
-
L
G
F
---------------
Q
G
V
-
T
L
G
I
--
A
V
T
A
F
A
M
G
S
T
A
S
V
Y
V
F
L
G
C
I
L
L
S
R
V
G
L
Y
G
F
S
N
G
E
F
E
L
R
Q
R
L
IPEGR
R
G
E
L
N
S
L
S
S
L
T
T
T
S
A
T
L
I
L
F
S
A
G
S
L
L
PQTED
F
K
Y
L
V
Y
V
S
L
A
A
V
L
L
A
N
V
V
F
I
K
W
S
SR