@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VN93: (2017-11-13 )
MSMIDILQLEGVQPIDYRNEDGCIMITVQPSGEHLETCPECGGRLYKHGQRINHFADTPLQMQPVKIEVIRTRYRCSECKSMITSQLSFLDEKRRATHRLIQQVRKRCLDRTFTQLAEDTGVVVNTIKNITLDFVEELERDIKFETPTIMGIDELKLMGTYRCVITNLAMNSLYDMLPERTQDTLIPYFAKLPDAEKVEWICSDMWRPFKKSFRLHLPNAKLIIDKFHVVRMASEALDTERKALQSSLDRDARLNMKKHLRWILLRRPNSLTEDQQRILGNLEKWHPEFKEAYDLKEQFYNIYEATTKDDAIQRFHEWESSIPKYLKSFRDVAKTVNNNFEDIFTYWDAPIRITIAYTEGHNGITRVANRMGRGYTFEVLRAKMLYNKVARSITTLKTPSSSLKSTKGYEGLTAFPTKQEKTKFEYGAYIPTLVELYGGDEDLDEELT
Atome Classification :
(20 SA)
----.......-..10........20........30-.----......---.-------40........50...--...---------------..60..----......70........80........90.....--------------...100.......110.......--120.......130.......140--------------........150........160.......------------170......-----.180.......------190.......200.......210....-...220-------........230.-......240.......250.......260.......270.......280....-....290.......300.-----......310..---.....320..--.....330.......340......-.350......---.360.......370.......380.......390.......400.......410.......420..----.....430-........---------.440......------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----MS
M
I
D
I
L
-QLEGVQPIDYRNED
G
C
I
M
I
T
VQPS-G----
E
H
L
E
T
C
---
P
-------
E
CG
G
R
L
Y
K
HG
Q
R
I
N
H--FAD---------------TPLQMQ----
P
V
K
I
E
V
I
R
T
R
Y
R
C
S
E
C
K
S
M
I
T
S
Q
L
S
F
L
D
E
K
R
R
A
--------------
T
H
R
L
I
Q
Q
V
R
K
R
C
L
D
R
T
F
T
Q
L
A
ED--T
G
V
V
V
N
T
I
K
N
I
T
L
D
F
V
E
E
L
E
R
D---------------IKFETP
T
I
M-
G
I
D
E
L
K
L
M
G
T
Y
R
C
V
I
T
N
L
A
------------
M
N
S
L
Y
D
MLP-----ERTQ
D
T
L
I
P
Y
F
------AKLP
D
A
E
K
V
E
W
I
C
S
D
M
W
R
P
F
K
K
S
F
R
LH-LPN
A
K
--------
L
I
I
D
K
F
H
V
V
R
M
A
-
S
E
A
L
D
T
E
R
K
A
L
Q
S
S
LD
R
D
A
RL
N
M
K
K
H
L
R
W
I
L
L
RRPNSL
T
E
D
Q
Q
R
I
L
G
-
N
L
E
K
W-
H
P
E
F
K
E
A
Y
D
L
K
E
Q
F
Y
N
I
Y
-----EATTK
D
D
A
I
Q
R
---
F
H
E
W
E
S
S
I
P
K
--
Y
L
K
S
F
R
D
V
A
K
T
VNN
N
F
E
D
I
F
T
YWD-A
P
I
R
I
T
I
A
Y
T---EGHN
G
I
T
R
V
A
N
RMGRG
Y
T
F
E
V
L
R
A
K
M
L
Y
N
K
V
A
R
S
I
TTLKTPSSSLKSTKGYEGLTAFPTKQEKTKF----EYGA
Y
I
---
P
T
L
V
E
L
YG---------GDEDLDEELT------------------------------------
48
Fugue
73.92
15%
1
- C2 -
-
5DO7
-
ABCG5_HUMAN
A:
[34-650]
EP
H
S
L
G
I
L
H
A
S
Y
S
R
Q
I
L
K
D
V
S
L
Y
V
E
S
G
Q
I
M
C
I
L
G
S
S
-
G
SG
K
T
T
L
L
D
A
M
---
S
GRLGRA
G
T
F
L
G
E
V
Y
V
N
G
R
A
L
R
R
EQ
F
Q
D
C
F
S
Y
V
L
Q
S
D
T
L
LSSL
T
V
R
E
T
L
----
H
Y
T
A
L
L
A
I
R
R
G
N
P
G
S
F
Q
K
K
V
E
A
V
M
A
E
L
S
L
S
H
V
A
DRLIGNYSLGGIS
T
G
E
R
R
R
V
S
I
A
A
Q
L
L
Q
D
P
K
V
M
L
F
D
E
PT
T
G
L
D
C
M
T
A
N
Q
I
V
V
L
L
V
E
L
A
R
R
N
R
I
V
V
L
TIHQPRSELF
Q
L
F
D
K
I
A
I
L
-
S
F
G
E
L
I
F
C
G
T
P
A
E
M
L
D
F
F
N
DCGYPCPEHSN
P
F
D
F
Y
M
D
L
T
S
VDTQS
K
E
R
E
I
E
T
S
K
R
V
------
Q
M
I
E
S
A
Y
K
K
S
A
I
C
H
K
T
L
K
N
I
E
R
M
K
H
L
K
T
L
P
M
V
P
F
K
T
K
D
SPG
V
F
S
K
L
G
V
L
L
R
R
V
-
T
R
N
L
V
R
N
K
L
A
V
I
T
R
L
L
Q
N
L
I
M
G
L
F
L
-
L
F
F
V
L
R
V
R
S
N
V
L
K
G
A
I
Q
D
R
V
G
-
L
L
Y
Q
F
V
G
A
T
P
Y
T
G
M
L
N
A
V
N
L
F
P
V
L
-----
R
A
V
S
D
Q
E
S
Q
D
G
---
L
Y
Q
K
W
Q
M
M
L
A
--
Y
A
L
H
V
L
P
F
S
V
V
A
T
M
I
F
S
S
V
C
-
Y
W
T
-
L
G
L
H
P
E
V
A
R
F
---
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
-
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
L
V
G
S
G
F
L
R
N
I
Q
E
M
P
I
P
F
K
I
I
S
Y
F
T
F
Q
K
Y
C
S
E
I
---
L
V
V
N
E
F
Y
G
L
N
F
T
CAFTQ
G
I
Q
F
I
E
K
T
C
P
GATSRFTM
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
S
55
Fugue
67.67
14%
-19
- C1 -
-
5AYN
9
?
A:
[7-426]
------------------------------------------
L
R
I
E
T
Q
---
L
-------
L
L
G
R
L
L
T
R
S
G
D
Q
A
W
D
--
F
V
V
---------------
P
F
A
L
L
V
I
F
PG
K
L
Q
V
A
A
F
Y
Y
L
I
V
K
I
G
T
F
L
L
T
P
S
S
G
K
W
I
D
-------------------
T
H
P
R
I
Q
V
V
K
W
G
V
W
L
Q
F
F
A
I
L
A
----
G
M
V
F
F
G
M
L
D
G
L
V
R
----
A
G
G
R
E
---------------
S
W
L
L
S
V
L
F
I
-
A
L
A
L
S
G
V
M
A
S
L
G
S
Q
I
T
D
I
S
------------
V
G
N
--
D
L
A
P
-----
S
L
V
A
P
E
K
L
T
H
F
N
S
W
L
R
R
I
D
L
A
T
E
V
G
A
P
I
L
A
G
A
L
F
-
P
L
A
G
L
F
L
I
G
-
L
W
N
L
V
--------
S
F
V
P
E
Y
F
L
L
R
N
V
-
I
Q
R
S
G
L
K
I
K
V
L
T
E
A
I
N
L
--
R
G
S
F
S
D
P
I
F
W
L
I
L
S
Y
A
L
L
W
L
S
----
V
L
S
P
H
G
V
L
L
-
A
A
Y
L
K
D
E
M
R
L
P
E
T
E
I
G
L
F
-----
R
G
L
G
A
V
F
G
L
I
S
---
T
V
S
F
P
Y
L
V
R
R
LG
L
I
S
S
S
R
W
H
L
G
F
Q
G
V
T
L
G
I
A
V
T
A
F
A
-
M
G
S
T
A
S
V
Y
V
F
---
L
G
C
I
L
L
S
R
V
G
L
Y
G
F
S
N
G
E
F
E
-
L
R
Q
R
L
I
P
E
G
R
R
G
E
L
N
S
L
S
S
L
T
T
T
S
A
T
L
I
L
F
S
A
G
S
L
L
P
---
Q
T
E
D
F
----
K
Y
L
V
Y
V
----
S
L
A
A
V
L
L
---------
A
N
V
V
F
I
K
W
S
S
R-----------------------------------
49
Fugue
59.17
18%
2
- C2 -
-
4N0N
-
A:
[22-422]
-------
S
A
V
C
-
T
V
C
G
A
A
P
V
A
K
S
A
C
G
G
W
F
C
G
N
C
V
P
Y
H
A
----
G
H
C
H
T
T
S
LF
A
-------
N
C
G
H
D
I
M
Y
R
S
T
Y
C
T
M
--
C
E
G
---------------
S
P
K
Q
M
V
----
P
------------
K
V
P
H
P
I
L
D
H
L
L
C
H
I
D
Y
G
S
K
E
--------------
E
L
T
L
V
V
A
-
D
G
R
T
T
S
P
P
G
R
Y
K
V
G
H
--
K
V
V
A
V
V
--
A
D
V
G
G
N
I
V
F
G
C
G
P
G
---------------
S
H
I
A
V
P
----------
L
Q
D
T
L
K
G
V
V
V
N
K
A
------------
L
K
N
A
A
A
S
---------------
E
Y
V
------
E
G
P
P
G
S
G
K
T
F
H
L
V
K
D
V
L
A
V
-
V
G
S
A
T
L
V
-
V
P
T
H
A
--------
S
M
L
D
C
I
N
K
L
K
Q
A
G
A
D
P
Y
F
V
V
P
K
Y
T
V
L
D
F
P
R
P
G
S
G
N
-------
I
T
V
R
L
P
Q
V
G
T
S
E
G
E
T
F
V
D
-
E
V
A
Y
F
-
S
P
-
V
D
L
A
R
I
L
T
Q
G
R
V
K
G
Y
G
D
LNQ
L
G
C
V
G
P
A
S
V
P
R
NLW
L
R
H
F
V
S
L
E
P
----
L
R
V
C
H
R
F
G
A
A
V
C
D
L
I
K
G
I
Y
P
Y
Y
E
P
A
P
H
T
T
K
V
V
F
V
PNP
D
F
E
K
G
V
V
I
T
A
Y
H
K
D
R
G
----------
L
G
H
R
T
I
D
S
I
Q
G
C
T
F
P
V
V
T
L
R
----------
L
P
T
P
Q
S
L
T
R
P
----
R
A
V
V
A
V
T
RA
S
Q
E
L
Y
I
Y
D
---------
P
F
D
Q
L
S
G
L
L
K
F-----------------------------------
11
PsiBlast_PDB
46.33
23%
-31
- C2 -
-
3QQC
-
A:
[121-304]
-----------------------------------------------
C
---
E
-------
T
C
G
G
R
A
---
G
E
C
P
G
H
--
F
G
H
---------------
I
E
L
A
R
P
----
V
I
H
V
G
F
A
K
T
I
Y
R
I
L
E
S
T
C
R
E
C
G
R
I
K
L
T
D
E
E
I
E
E
--------------
Y
M
K
K
I
E
L
A
R
N
R
--
R
S
E
F
N
E
I
I
K
E
----
I
H
K
K
A
K
E
R
M
V
C
P
-------
P
---------------
I
K
F
E
K
P
T
I
Y
W
E
I
R
K
D
---
N
E
Y
R
---
H
R
L
M
------------
P
T
E
V
R
D
W
L
------
E
K
I
P
D
K
D
L
P
L
L
------
G
L
D
P
E
K
S
R
P
E
W
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.21
38%
-143
- C4 -
-
3UYJ
1
KDM8_HUMAN
A:
[102-148]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
45.12
6%
-79
- C2 -
-
2X0C
-
TLN1_MOUSE
A:
[1352-1659]
----------------------------
I
D
P
F
T
K
H
G
-
Q
----
K
E
C
D
N
A
---
L
-------
R
Q
L
E
T
V
R
E
L
L
E
N
P
V
Q
--
P
I
N
---------------
D
M
-------------------
S
Y
F
G
C
L
D
S
V
M
E
N
S
K
V
L
G
E
A
M
T
G
--------------
I
S
Q
N
A
K
N
G
N
L
P
E
F
G
D
A
I
A
T
A
S
K
A
--
L
C
G
F
T
E
A
A
A
Q
A
A
Y
L
V
G
V
S
D
P
N
S
---------------
Q
A
G
Q
Q
G
L
V
E
-
P
T
Q
F
A
R
A
N
Q
A
I
Q
M
A
C
Q
S
L
G
------------
E
P
G
---------------------------------------------------------
C
T
Q
A
--------
Q
V
L
S
A
A
T
I
V
A
K
H
-
T
S
A
L
C
N
S
C
R
L
A
S
A
R
T
A
N
P
T
A
K
R
Q
F
V
Q
S
A
K
E
V
A
N
S
T
A
N
L
V
K
T
I
K
A
L
--------------------------------
D
G
D
F
T
E
E
N
R
A
Q
---
C
R
A
A
T
A
P
L
L
E
--
A
V
D
N
L
S
A
F
A
S
N
P
E
F
S
--------
S
-
V
P
A
Q
I
S
P
E
G
R
---
A
A
M
E
P
I
V
I
S
A
K
T
M
L
E
S
A
G
G
L
I
Q
T
A
R
A
L
A
V
N
P
R
D
P
P
R
W
S
V
L
A
G
H
S
R
T
V
S
D
S
I
K
K
L
I
T
S
M
R
D
K
A
P
G
Q
L
----------------------------------------------------------------------------
21
PsiBlast_CBE
45.10
38%
-139
- C4 -
-
3UYJ
1
B:
[102-148]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
44.63
38%
-147
- C4 -
-
4QU1
2
A:
[90-130]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
44.59
41%
-133
- C4 -
-
4AAP
1
B:
[96-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.42
38%
-148
- C4 -
-
4GJY
1
A:
[89-129]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
44.21
56%
-104
- C3 -
-
1V9P
-
DNLJ_THEFI
A:
[407-429]
---------------------------------------------
E
T
C
---
P
-------
E
C
G
H
R
L
V
K
E
G
K
--
V
H
--
R
C
P
---------------
N
P
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
43.97
38%
-130
- C4 -
-
4GAZ
1
KDM8_HUMAN
A:
[98-144]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
43.90
38%
-148
- C4 -
-
5FBJ
2
A:
[90-130]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
43.61
38%
-130
* C4 *
-
4GAZ
1
B:
[98-144]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
43.55
38%
-112
- C4 -
-
4AAP
1
KDM8_HUMAN
A:
[93-134]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
43.19
38%
-139
- C4 -
-
4GJZ
1
A:
[89-129]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
Y
L
A
------------
Q
H
Q
L
F
D
Q
I
P
-----
E
L
K
Q
D
I
S
I
P
D
Y
------
C
S
L
G
D
G
E
E
E
E
-
I
T
I
N
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
38.61
13%
-98
* C3 *
-
5K2M
-
?
F:
[19-34]
---------------------------------------------------------------------------------------------------------------
H
Q
I
V
E
C
P
V
C
G
A
E
L
E
V
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
36.86
30%
-44
- C3 -
-
4RVZ
-
?
Z:
[349-378]
--------------------------------------------
N
P
I
C
---
P
-------
S
C
G
R
R
M
E
S
A
G
R
G
-----------------------------------------
Q
G
F
R
C
K
K
C
R
T
K
A
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
36.73
17%
-73
- C3 -
-
2K5C
-
?
A:
[46-63]
------------------------------------------------------------------------------------------------------------
Q
V
E
E
F
V
F
K
C
P
V
C
G
E
E
F
Y
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
36.33
13%
-80
- C3 -
-
3WWL
-
LYSW_THET8
A:
[20-34]
---------------------------------------------------------------------------------------------------------------
G
E
L
V
V
C
E
D
C
G
A
E
L
E
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------