@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VNE9: (2017-11-14 )
MLHCCFTTMPLNDNFVYAPPQDPLSILFEDDDLIVVDKPAGLLSVMGRLPEHHDSAYLRVLEKFPLAKVTHRLDMATSGLLMFAKHRDAEVAVSKMFQARTVKKHYIALVQGQVKQEGSVEVPLITDWENRPRQIVHFELGKHAKTLFQPLVYDATTDQSRVLLEPVTGRSHQLRVHMMHIGHPIMGDKLYHPEPKRFHLNRMALHAAYLAFQHPLKGTDVVIESQVPF
Atome Classification :
(20 SA)
-------------------------------------------------.........10........20.-------.-......30........40..--......50-........60.-..-------....---.70........80........90........100.......-110...-..-..120.......130-..---------------..-----..-.140...-....150..---------.--....160.......170......-.180........190-...-------...-------------------.----------.200........210.......220.......----------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------M
L
H
C
C
F
TTMPLND
N
F
V
YAPPQD-------
P
-
L
S
I
L
FEDD
D
L
I
V
V
DKP
A
G
L
L
--
S
V
M
GRLPE-HH
D
S
A
Y
L
R
V
L
E
-KF-------
P
L
A
K
---
V
T
H
R
L
D
MATS
G
L
L
M
F
AKHR
D
A
E
V
A
V
S
K
M
F
Q
A
R
T
V
K
K
H
Y
I
A
L
-
V
QGQVK-QE-GSVEV
P
L
ITDWENRP-
R
Q
---------------
I
V
-----
H
F
-
E
L
G
K
H
A
K
-
T
L
F
Q
P
L
VYD---------A--TTDQS
R
V
L
L
EPVTGR
S
H
Q
L
R
V
H
M
-MH-IGHPIMGDKLY--HPE-------PKR-------------------
F
----------
H
L
N
-
R
M
A
L
H
A
A
Y
L
A
F
QHPLKGT
D
V
V
I
ESQVPF----------------------
1
PsiBlast_PDB
94.21
46%
-57
- C6 -
-
2I82
1
RLUA_ECOLI
A:
[4-217]
-----------------------------------------------------------------
Y
N
P
P
Q
E
-------
P
W
L
V
I
L
Y
Q
D
D
H
I
M
V
V
N
K
P
S
G
L
L
--
S
V
P
G
R
L
E
E
-
H
K
D
S
V
M
T
R
I
Q
R
-
D
Y
-------
P
Q
A
E
---
S
V
H
R
L
D
M
A
T
S
G
V
I
V
V
A
L
T
K
A
A
E
R
E
L
K
R
Q
F
R
E
R
E
P
K
K
Q
Y
V
A
R
-
V
W
G
H
P
S
P
A
E
-
G
L
V
D
L
P
L
I
C
D
W
P
N
R
P
-
K
Q
---------------
K
V
-----
C
Y
-
E
T
G
K
P
A
Q
-
T
E
Y
E
V
V
E
Y
----------
A
--
A
D
N
T
A
R
V
V
L
K
P
I
T
G
R
S
H
Q
L
R
V
H
M
-
L
A
-
L
G
H
P
I
L
G
D
R
F
Y
--
A
S
P
-------
E
A
R
-------------------
A
----------
M
A
P
-
R
L
L
L
H
A
E
M
L
T
I
T
H
P
A
Y
G
N
S
M
T
F
K
A
P
A
D
F
----------------------
24
HHSearch
92.20
46%
-58
- C6 -
-
2I82
1
RLUA_ECOLI
A:
[7-217]
-------------------------------------------------------------------
P
Q
E
P
-------
W
-
L
V
I
L
Y
Q
D
D
H
I
M
V
V
N
K
P
S
G
L
L
--
S
V
P
G
R
L
E
E
-
H
K
D
S
V
M
T
R
I
Q
R
-
D
Y
-------
P
Q
A
E
---
S
V
H
R
L
D
M
A
T
S
G
V
I
V
V
A
L
T
K
A
A
E
R
E
L
K
R
Q
F
R
E
R
E
P
K
K
Q
Y
V
A
R
-
V
W
G
H
P
S
P
A
E
-
G
L
V
D
L
P
L
I
C
D
W
P
N
R
P
-
K
Q
---------------
K
V
-----
C
Y
-
E
T
G
K
P
A
Q
-
T
E
Y
E
V
V
E
Y
A
---------
A
---
D
N
T
A
R
V
V
L
K
P
I
T
G
R
S
H
Q
L
R
V
H
M
-
L
A
-
L
G
H
P
I
L
G
D
R
F
Y
--
A
S
P
-------
E
A
R
-------------------
A
----------
M
A
P
-
R
L
L
L
H
A
E
M
L
T
I
T
H
P
A
Y
G
N
S
M
T
F
K
A
P
A
D
F
----------------------
25
HHSearch
91.32
46%
-57
* C6 *
-
2I82
1
RLUA_ECOLI
D:
[7-217]
-------------------------------------------------------------------
P
Q
E
P
-------
W
-
L
V
I
L
Y
Q
D
D
H
I
M
V
V
N
K
P
S
G
L
L
--
S
V
P
G
R
L
E
E
-
H
K
D
S
V
M
T
R
I
Q
R
-
D
Y
-------
P
Q
A
E
---
S
V
H
R
L
D
M
A
T
S
G
V
I
V
V
A
L
T
K
A
A
E
R
E
L
K
R
Q
F
R
E
R
E
P
K
K
Q
Y
V
A
R
-
V
W
G
H
P
S
P
A
E
-
G
L
V
D
L
P
L
I
C
D
W
P
N
R
P
-
K
Q
---------------
K
V
-----
C
Y
-
E
T
G
K
P
A
Q
-
T
E
Y
E
V
V
E
Y
A
---------
A
---
D
N
T
A
R
V
V
L
K
P
I
T
G
R
S
H
Q
L
R
V
H
M
-
L
A
-
L
G
H
P
I
L
G
D
R
F
Y
--
A
S
P
-------
E
A
R
-------------------
A
----------
M
A
P
-
R
L
L
L
H
A
E
M
L
T
I
T
H
P
A
Y
G
N
S
M
T
F
K
A
P
A
D
F
----------------------
4
PsiBlast_PDB
75.94
35%
-36
- C6 -
-
1XPI
3
RLUC_ECOLI
A:
[7-214]
----------------------------------------------------------------------------------
I
L
Y
E
D
D
H
I
L
V
L
N
K
P
S
G
T
A
--
V
H
G
G
S
G
L
S
-
F
G
V
I
E
G
L
R
A
L
R
--
A
-------
R
F
L
E
---
L
V
H
R
L
D
R
D
T
S
G
V
L
L
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
-
V
R
G
Q
W
Q
-
S
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
G
-
E
R
---------------
I
V
-----
R
V
S
Q
E
G
K
P
S
E
-
T
R
F
K
--
V
E
E
---------
R
--
Y
A
F
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
T
-
Q
Y
-
A
G
H
P
I
A
F
D
D
R
Y
--
G
D
R
E
F
D
R
Q
L
T
E
A
G
-------------------
T
----------
G
L
N
-
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
--------------------------
21
PsiBlast_CBE
74.33
35%
-6
- C6 -
-
1XPI
2
RLUC_ECOLI
B:
[7-214]
----------------------------------------------------------------------------------
I
L
Y
E
D
D
H
I
L
V
L
N
K
P
S
G
T
A
--
V
H
G
G
S
G
L
S
-
F
G
V
I
E
G
L
R
A
L
R
P
E
A
-------
R
F
L
E
---
L
V
H
R
L
D
R
D
T
S
G
V
L
L
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
-
V
R
G
Q
W
Q
-
S
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
G
-
E
R
---------------
I
V
-----
R
V
S
Q
E
G
K
P
S
E
-
T
R
F
K
--
V
E
E
---------
R
--
Y
A
F
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
T
-
Q
Y
-
A
G
H
P
I
A
F
D
D
R
Y
--
G
D
R
E
F
D
R
Q
L
T
E
A
G
-------------------
T
----------
G
L
N
-
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
--------------------------
7
PsiBlast_PDB
72.92
34%
-11
- C6 -
-
1V9K
-
RLUC_ECOLI
A:
[4-211]
----------------------------------------------------------------------------------
I
M
Y
E
D
D
H
I
L
V
L
N
K
P
S
G
T
A
--
V
H
G
G
S
G
L
S
-
F
G
V
I
E
G
L
R
A
L
R
P
E
A
-------
R
F
L
E
---
L
V
H
R
L
D
R
D
T
S
G
V
L
L
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
-
V
R
G
Q
W
Q
-
S
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
G
-
E
R
---------------
I
V
-----
R
V
S
Q
E
G
K
P
S
E
-
T
R
F
K
--
V
E
E
---------
R
--
Y
A
F
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
T
-
Q
Y
-
A
G
H
P
I
A
F
D
D
R
Y
--
G
D
R
E
F
D
R
Q
L
T
E
A
G
-------------------
T
----------
G
L
N
-
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
--------------------------
23
HHSearch
72.50
33%
-11
- C6 -
-
1PRZ
-
RLUD_ECOLI
A:
[80-303]
--------------------------------------------------------------------
Q
D
I
-------
P
-
L
D
I
V
Y
E
D
E
D
I
I
V
I
N
K
P
R
D
L
V
--
V
H
P
G
A
G
N
--
P
D
G
T
V
L
N
A
L
L
H
-
Y
Y
PPIADV-
P
R
A
G
---
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
----------------
M
A
-----
V
H
-
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
----
V
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
--
G
G
R
-------
P
R
P
P
KGAS
E
A
F
I
S
T
L
-------
R
----------
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
----------------------
26
HHSearch
71.24
32%
-14
- C6 -
-
1V9F
-
RLUD_ECOLI
A:
[80-302]
---------------------------------------------------------------------
D
I
-------
P
-
L
D
I
V
Y
E
D
E
D
I
I
I
I
N
K
P
R
D
L
V
--
V
H
P
G
A
G
N
--
P
D
G
T
V
L
N
A
L
L
H
-
Y
Y
PPIADV-
P
R
A
G
---
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
----------------
M
A
-----
V
H
-
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
----
V
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
--
G
G
R
-------
P
R
P
PKGAS
E
A
F
I
S
T
L
-------
R
----------
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
----------------------
6
PsiBlast_PDB
68.84
32%
15
- C6 -
-
1PRZ
-
RLUD_ECOLI
A:
[79-302]
--------------------------------------------------------------------
P
Q
D
I------
P
-
L
D
I
V
Y
E
D
E
D
I
I
V
I
N
K
P
R
D
L
V
--
V
H
P
G
--
A
G
-
N
P
D
G
T
V
L
N
A
L
L
-
H
Y
YPPIADV
P
R
A
G
---
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
M
---------------
A
V
-----
H
--
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
--
V
H
T
R
L
R
L
R
L
E
--
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
GG
R
P
R
-------
P
P
K
-------------------
G
AS
E
A
F
I
S
T
L
R
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
-----------------------
2
PsiBlast_PDB
68.24
32%
16
- C6 -
-
1V9F
-
RLUD_ECOLI
A:
[78-301]
--------------------------------------------------------------------
P
Q
D
I------
P
-
L
D
I
V
Y
E
D
E
D
I
I
I
I
N
K
P
R
D
L
V
--
V
H
P
G
--
A
G
-
N
P
D
G
T
V
L
N
A
L
L
-
H
Y
YPPIADV
P
R
A
G
---
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
M
---------------
A
V
-----
H
--
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
--
V
H
T
R
L
R
L
R
L
E
--
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
GG
R
P
R
-------
P
P
K
-------------------
G
AS
E
A
F
I
S
T
L
R
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
-----------------------
22
HHSearch
67.09
34%
3
- C6 -
-
1V9K
-
RLUC_ECOLI
B:
[2-215]
--------------------------------------------------------------------------------
D
V
I
M
Y
E
D
D
H
I
L
V
L
N
K
P
S
G
T
A
--
V
H
G
G
S
G
L
---
S
F
G
V
I
E
G
L
R
A
-
L
R
PEA----
R
F
L
E
---
L
V
H
R
L
D
R
D
T
S
G
V
L
L
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
-
V
R
G
Q
W
Q
S
H
V
-
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
G
E
R
I
---------------
V
R
-----
V
S
-
Q
E
G
K
P
S
E
-
T
R
F
K
V
E
E
R
Y
---------
A
----
F
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
T
-
Q
Y
-
A
G
H
P
I
A
F
D
D
R
Y
--
G
D
R
-------
E
F
D
RQLTEAG------------
T
----------
G
L
N
-
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
P
M
D
E
----------------------
27
HHSearch
67.07
29%
-24
- C6 -
-
5VBB
1
RUSD1_HUMAN
A:
[5-230]
--------------------------------------------------------------------
S
V
E
-------
N
-
L
S
I
V
Y
R
S
R
D
F
L
V
V
N
K
H
W
D
V
R
--
I
D
---------
L
T
L
Q
K
Q
L
R
Y
-
R
F
P-------
G
F
R
---
F
C
H
Q
L
D
F
S
T
S
G
A
L
C
V
A
L
N
K
A
A
A
G
S
A
Y
R
C
F
K
E
R
R
V
T
K
A
Y
L
A
L
-
L
R
G
H
I
Q
E
S
R
-
V
T
I
S
H
A
I
G
R
N
S
T
E
G
R
A
H
T
---------------
M
C
IEGSQ
G
C
-
E
N
P
K
P
S
L
-
T
D
L
V
V
L
E
H
G
---------
L
Y
A
G
D
P
V
S
K
V
L
L
K
P
L
T
G
R
T
H
Q
L
R
V
H
C
-
S
A
-
L
G
H
P
V
V
G
D
L
T
Y
--
G
E
V
-------
S
G
R
E------------------
D
----------
R
P
F
-
R
M
M
L
H
A
F
Y
L
R
I
P
T
D
--
T
E
C
V
E
V
C
T
P
D
P
F
----------------------
3
PsiBlast_PDB
66.86
32%
15
- C6 -
-
2IST
-
RLUD_ECOLI
A:
[78-301]
--------------------------------------------------------------------
P
Q
D
I------
P
-
L
D
I
V
Y
E
D
E
D
I
I
I
I
N
K
P
R
D
L
V
--
V
H
P
G
--
A
G
-
N
P
D
G
T
V
L
N
A
L
L
-
H
Y
YPPIADV
P
R
A
G
---
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
M
---------------
A
V
-----
H
--
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
--
V
H
T
R
L
R
L
R
L
E
--
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
GG
R
P
R
-------
P
P
K
-------------------
G
AS
E
A
F
I
S
T
L
R
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
-----------------------
5
PsiBlast_PDB
65.64
32%
23
- C6 -
-
1QYU
-
RLUD_ECOLI
A:
[79-302]
--------------------------------------------------------------------
P
Q
D
I------
P
-
L
D
I
V
Y
E
D
E
D
I
I
I
I
N
K
P
R
D
L
V
--
V
H
P
G
--
A
G
-
N
P
D
G
T
V
L
N
A
L
L
-
H
Y
YPPIADV
P
R
A
G
---
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
M
---------------
A
V
-----
H
--
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
--
V
H
T
R
L
R
L
R
L
E
--
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
GG
R
P
R
-------
P
P
K
-------------------
G
AS
E
A
F
I
S
T
L
R
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
-----------------------
28
HHSearch
63.29
26%
-17
- C6 -
-
5UBA
-
RUSD4_HUMAN
A:
[22-277]
-------------------------------------------------------------------
A
K
A
L
-------
T
-
R
G
I
L
H
Q
D
K
N
L
V
V
I
N
K
P
Y
G
L
P
--
V
H
G
----
Q
L
C
I
T
D
V
L
P
I
L
A
K
-
M
L
HGHKA--
E
P
L
H
---
L
C
H
R
L
D
K
E
T
T
G
V
M
V
L
A
W
D
K
D
M
A
H
Q
V
Q
E
L
F
R
T
R
Q
V
V
K
K
Y
W
A
I
-
T
V
H
V
P
M
P
S
A
-
G
V
V
D
I
P
I
V
E
K
-------
M
T
L
S
P
S
Y
R
M
D
DG
K
M
V
K
V
R
-----
R
S
-
R
N
A
Q
V
A
V
-
T
Q
Y
Q
V
L
S
S
T
---------
L
----
S
S
A
L
V
E
L
Q
P
I
T
G
I
K
H
Q
L
R
V
H
L
-
S
F
G
L
D
C
P
I
L
G
D
H
K
Y
--
S
D
W
-------
N
R
L
A
P
Q
K
L
S
V
G
T
L
K
K
L
GLEQSK
A
----------
R
Y
I
-
P
L
H
L
H
A
R
Q
L
I
L
P
A
L
---
E
E
L
N
L
V
C
K
L
P
R
----------------------
43
Fugue
61.68
30%
10
- C6 -
-
2IST
-
RLUD_ECOLI
A:
[1-324]
A
Q
R
V
Q
L
T
A
T
V
S
ENQLGQR
L
D
Q
A
L
A
E
M
F
PDYS
R
S
R
I
K
E
W
I
L
D
QR
V
L
V
NGK
V
C
D
K
P
K
E
K
V
L
G
G
E
Q
V
A
I
N
A
E
I
E
R
F
E
P
Q
DI
P
-
L
D
I
V
Y
E
D
E
D
I
I
I
I
N
K
P
R
D
L
V
VH
P
G
A
G
N
P
D
G
-
T
V
L
N
A
L
L
H
Y
Y
P
-
P
I
-------
A
D
V
P
RAG
I
V
H
R
L
D
K
D
T
T
G
L
M
V
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
-
A
I
G
H
M
T
-
A
G
-
G
T
V
D
E
P
I
S
R
H
P
T
K
R
T
-
H
M
---------------
A
V
-----
H
--
P
M
G
K
P
A
V
-
T
H
Y
R
I
M
E
H
F
---------
R
--
V
H
T
R
L
R
L
R
L
E
--
T
G
R
T
H
Q
I
R
V
H
M
-
A
H
-
I
T
H
P
L
V
G
D
P
V
Y
--
G
G
R
-------
P
R
P
P
K
GAS
E
A
F
I
S
T
L
-------
R
----------
K
F
D
-
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
A
D
F
E
E
H
KDEVDW
9
PsiBlast_PDB
56.87
29%
-13
- C6 -
-
5UBA
-
RUSD4_HUMAN
A:
[28-223]
---------------------------------------------------------------------------------
G
I
L
H
Q
D
K
N
L
V
V
I
N
K
P
Y
G
L
P
--
V
H
G
----
Q
-
L
C
I
T
D
V
L
P
I
L
A
-
K
M
L
HGHKA
E
P
L
-
H
---
L
C
H
R
L
D
K
E
T
T
G
V
M
V
L
A
W
D
K
D
M
A
H
Q
V
Q
E
L
F
R
T
R
Q
V
V
K
K
Y
W
A
I
T
V
H
V
P
M
P
-
S
A
-
G
V
V
D
I
P
I
V
E
K
--------
M
T
L
S
P
S
Y
R
M
D
DG
K
--
M
V
-----
K
V
-
R
R
S
R
N
A
Q
V
A
V
T
Q
Y
Q
V
L
S
---------
S
--
T
L
S
S
A
L
V
E
L
Q
P
I
T
G
I
K
H
Q
L
R
V
H
L
S
F
G
-
L
D
C
P
I
L
G
D
H
K
Y
---------------------------------------------------------------------------------------------------
33
HHSearch
53.35
19%
-96
- C6 -
-
2GML
-
RLUF_ECOLI
A:
[1-145]
--------------------------------------------------------------------------------------
D
L
V
L
I
A
L
N
K
P
V
G
I
V
--
S
T
T
E
D
G
---
E
R
D
N
I
V
D
F
V
N
H
--
S
-------
K
R
V
F
---
P
I
G
R
L
D
K
D
S
Q
G
L
I
F
L
T
N
H
G
D
L
V
N
K
I
L
R
A
G
--
N
D
H
E
K
E
Y
L
V
T
-
V
D
K
P
I
T
-
E
E
--
F
I
R
G
-
M
S
A
---
G
V
P
-------------------
I
-----
L
G
-
T
V
T
K
K
C
K
-
V
K
K
---------------
E
----
A
P
F
V
F
R
I
T
L
V
Q
G
L
N
R
Q
I
R
R
M
C
-
E
H
-
F
G
Y
E
V
K
K
L
E
R
T
--
R
I
M
-------
N
--------------------------------------------------------------------------------------
34
HHSearch
51.94
20%
-87
- C6 -
-
3DH3
-
RLUF_ECOLI
B:
[62-209]
----------------------------------------------------------------------------------
R
E
A
E
D
L
V
L
I
A
L
N
K
P
V
G
I
V
--
S
T
T
E
D
G
E
---
R
D
N
I
V
D
F
V
N
H
--
S
-------
K
R
V
F
---
P
I
G
R
L
D
K
D
S
Q
G
L
I
F
L
T
N
H
G
D
L
V
N
K
I
L
R
A
G
--
N
D
H
E
K
E
Y
L
V
T
-
V
D
K
P
I
T
-
E
E
--
F
I
R
G
-
M
S
---
A
G
V
P
-------------------
I
--------
L
G
---
T
V
-
T
K
K
C
K
V
K
K
----------
E
----
A
P
F
V
F
R
I
T
L
V
Q
G
L
N
R
Q
I
R
R
M
C
-
E
H
-
F
G
Y
E
V
K
K
L
E
R
T
--
R
I
M
----------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.01
33%
-17
- C6 -
-
5VBB
1
RUSD1_HUMAN
A:
[61-213]
---------------------------------------------------------------------------------------------------------------------------------------
R
---
F
C
H
Q
L
D
F
S
T
S
G
A
L
C
V
A
L
N
K
A
A
A
G
S
A
Y
R
C
F
K
E
R
R
V
T
K
A
Y
L
A
L
-
L
R
G
H
I
Q
-
E
S
-
R
V
T
I
S
H
A
I
G
R
N
S
T
E
G
-
R
A
---------------
H
T
-----
M
C
-
I
E
G
S
Q
G
C
-
E
N
P
K
P
S
L
T
D
L
V
V
L
E
H
G
L
Y
A
--
G
D
P
V
S
K
V
L
L
K
P
L
T
G
R
T
H
Q
L
R
V
H
C
-
S
A
-
L
G
H
P
V
V
G
D
L
T
Y
--
G
E
V
-------
S
G
R
-------------------
E
----------
D
R
P
F
R
M
M
L
H
A
F
Y
L
-----------------------------------------