@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VP12: (2017-11-19 )
MKIRLITRPINKIKQVILDFIHHNHIINWTPLQKSALMLTLACAMNFSWILWKGYILITPSIWQWANLSLVESQIWLNLLTLFLLAVLIIPCYRYKDQAWAQKIVPLISVQAFMLMLCHDGYLIGSISPATMVGYVGTIGVGLVLFERKIVYSAFIPATIILAVCTYLSMTGVISYAPLFNFTAMRHAQTNPFWLGSMLFFIMPILVACFILFEILLIQWRQRETYIQRLSQIDPLTNVLNRRSLNTHLEALHEQQFDYAVILLDIDHFKKINDIYGHHQGDQVLIEIARCLSENLRNEDIIGRFGGEEFILLLPHTDILQAEKIAERCRQALQELTIFNNQNIQIHVSASFGISSSAFANDPYLVIRQADQALYAVKASGRNKVRTFHQLPQIKSI
Atome Classification :
(20 SA)
-.........10........20........30........40..---------------......50...-------.....60........70........80........90........100...--...-------------------------------.110.......120.......130.......140.......150.......160.......170.......180.......190---.......200.......210.......220.......230.---......240.....----..250---.....----..----.----.----260.......270.......280.......290....-...300.......310.......320.......330-.......-.340-.-..---.....350....---..-.---360-....-...370.......380.......390.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-
M
K
I
R
L
I
TR
P
I
N
K
I
K
Q
V
I
L
D
F
I
HHNHI
I
N
W
TPLQKS
A
L
M
L
T
L
A
C
---------------AMN
F
S
W
I
L
W
K
G
-------
Y
I
L
ITPSIWQWA
N
L
S
L
V
E
S
Q
I
W
L
N
L
L
T
L
F
L
L
A
V
L
I
IPCYRY
K
D
Q
A
W
A
Q
K
I
V
--
P
L
I
-------------------------------
S
V
Q
A
F
M
L
M
L
CHD
G
Y
L
IGSI
S
P
A
T
M
V
G
Y
V
G
T
I
G
V
G
L
V
L
F
E
R
K
I
V
Y
S
A
F
I
P
A
T
I
I
L
A
V
C
T
Y
L
S
M
T
G
VISYAPLF
N
F
T
A
M
RHAQTNP---
F
W
L
G
S
M
L
F
F
I
M
P
I
L
V
A
C
F
I
L
F
E
I
L
L
I
Q
W
R
Q
R
E
T
Y
I
Q
R
L
SQI---
D
P
L
T
N
V
L
N
RRS
L
N
T
----
H
L
E
-----
A
L
H
E
Q----QF----
D
----
Y
----
A
V
I
L
L
D
I
D
H
F
K
K
I
N
D
I
YGHHQG
D
Q
V
L
I
E
I
A
R
C
L
S
E
NL-RNED
I
I
G
R
FGG
E
E
F
I
L
L
LPH
T
D
I
L
Q
A
E
K
I
A
E
R
C
R
Q
--
A
L
Q
E
L
TI-FN-N-Q-
N
I
---
Q
I
H
V
S
A
SFGISS---SA-F---AND-
P
Y
L
V
-
I
R
QADQ
A
L
Y
A
V
KASGRN
K
V
R
T
F
H
QLPQIKSI
41
Fugue
80.59
27%
-49
- C5 -
-
4ZMU
-
?
A:
[5-345]
--
M
L
A
C
P
L
P
P
D
E
A
L
R
Q
Q
A
L
D
D
M
A
----
L
V
D
T
P
A
E
H
Y
L
D
A
L
V
E
L
A
---------------
R
E
T
F
G
V
K
T
V
L
I
-------
S
L
I
D
H
D
R
Q
W
F
K
A
R
I
G
L
D
A
E
Q
T
P
R
D
L
-
S
F
C
G
H
A
I
L
A
S
E
P
L
M
V
T
D
A
S
R
D
P
R
F
H
DN
P
L
V
-------------------------------
T
G
P
P
F
I
------
R
F
Y
A
G
E
P
L
H
A
S
N
G
Q
A
I
G
T
L
C
L
I
D
-------------------------------
P
S
P
R
L
L
D
L
R
E
G
R
Q
L
N
R
L
S
---
I
L
A
E
G
Y
L
Q
L
R
S
L
T
E
H
T
R
F
L
R
Q
E
I
------
D
R
E
---
Q
R
K
S
L
L
---
D
P
L
T
Q
L
W
N
R
A
G
F
H
A
L
H
Q
H
E
L
E
-----
L
A
R
A
S
----
D
Q
----
R
----
I
----
G
I
I
Y
S
D
I
D
H
F
K
R
I
N
D
T
L
G
H
R
A
G
D
S
V
L
R
E
A
A
S
R
L
R
A
A
L
-
R
P
E
D
L
L
A
R
F
G
G
E
E
F
V
A
M
V
R
V
R
E
T
T
E
L
T
M
I
A
N
R
I
R
E
--
L
M
E
A
-
T
P
-
I
D
-
C
-
A
-
G
T
---
S
V
P
V
T
I
S
A
G
C
T
L
---
A
G
-
S
---
G
E
E
-
P
E
R
A
-
L
A
R
A
D
A
A
L
Y
D
A
K
R
A
G
R
N
R
V
V
S
V
---------
37
Fugue
79.51
21%
-37
- C5 -
-
1W25
3
PLED_CAUCN
A:
[1-454]
S
A
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
LPD
I
I
L
L
D
VMMPGMD
G
F
T
V
C
R
K
L
K
D
D
PTTRH
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
L
T
R
F
K
L
V
I
D
E
L
--
R
Q
R
E
A
S
GRRMGVIAGAAARLDG
L
G
G
R
V
L
I
V
D
DN
E
R
Q
A
Q
R
V
A
A
E
L
G
V
E
H
R
P
V
I
E
S
D
P
E
K
A
K
I
S
A
G
G
P
V
D
L
V
I
V
N
A
A
A
K
N
F
D
G
L
R
F
T
A
A
L
R
S
E
E
R
T
R
Q
L
P
V
L
A
M
V
D
P
D
D
R
G
R
M
V
K
A
L
E
I
G
VN
D
I
L
S
R
P
I
D
P
Q
E
L
S
A
R
V
K
T
Q
I
Q
R
K
R
Y
T
D
Y
L
R
N
N
L
D
H
S
L
E
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
----
L
G
G
D
P
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
--
H
V
S
G
S
P
F
T
V
A
-
H
-
G
-
R
E
---
M
L
N
V
T
I
S
I
G
V
S
A
T
--
A
G
-
E
---
G
D
T
-
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
------
4
PsiBlast_PDB
68.76
38%
-19
- C5 -
-
2WB4
4
PLED_CAUCN
A:
[288-449]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
L
G
G
D
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
P
F
T
V
-
A
H
-
G
-
R
-
E
M
----
L
N
V
T
I
S
I
G
V
S
A
---
T
A
-
G
---
E
G
D
T
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
------------
3
PsiBlast_PDB
68.67
38%
-22
- C5 -
-
2V0N
5
PLED_CAUCN
A:
[287-448]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
L
G
G
D
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
P
F
T
V
-
A
H
-
G
-
R
-
E
M
----
L
N
V
T
I
S
I
G
V
S
A
---
T
A
-
G
---
E
G
D
T
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
------------
23
PsiBlast_CBE
68.06
38%
-26
- C5 -
-
2WB4
5
PLED_CAUCN
B:
[288-449]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
L
G
G
D
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
P
F
T
V
-
A
H
-
G
-
R
-
E
M
----
L
N
V
T
I
S
I
G
V
S
A
---
T
A
-
G
---
E
G
D
T
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
------------
21
PsiBlast_CBE
67.29
38%
-20
- C5 -
-
2V0N
5
PLED_CAUCN
B:
[287-448]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
LGGD
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
HV
S
G
S
P
F
T
V
-
A
H
-
G
-
R
-
E
M
----
L
N
V
T
I
S
I
G
V
S
A
---
T
A
-
G
---
E
G
D
T
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
------------
22
PsiBlast_CBE
67.14
38%
-16
- C5 -
-
1W25
2
PLED_CAUCN
B:
[287-448]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
LGGD
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
HV
S
G
S
P
F
T
V
-
A
H
-
G
-
R
-
E
M
----
L
N
V
T
I
S
I
G
V
S
A
---
T
A
-
G
---
E
G
D
T
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
------------
1
PsiBlast_PDB
66.19
39%
5
- C5 -
-
3IGN
2
?
A:
[6-166]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
S
M
T
---
D
R
L
T
G
L
L
N
R
G
T
W
E
N
----
L
V
D
-----
A
E
Y
E
R
----
F
R
----
R
----
Y
G
Q
A
T
S
L
V
M
F
D
I
D
H
F
K
P
V
N
D
T
Y
G
H
L
A
G
D
E
V
I
R
H
T
A
D
V
T
R
N
N
I
-
R
Q
S
D
S
A
G
R
Y
G
G
E
E
F
G
I
I
L
P
E
T
D
A
E
S
A
R
V
I
C
E
R
I
R
E
--
A
I
E
K
S
T
V
-
S
T
-
S
-
A
-
G
----
D
I
Q
Y
T
V
S
M
G
I
A
Q
---
L
T
-
E
---
T
P
E
-
N
Y
M
Q
W
M
Q
K
A
D
E
A
L
Y
K
A
K
E
S
G
R
N
K
V
------------
2
PsiBlast_PDB
66.06
38%
-16
- C5 -
-
1W25
3
PLED_CAUCN
A:
[287-448]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
----
A
T
L
G
G
D
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
P
F
T
V
-
A
H
-
G
-
R
-
E
M
----
L
N
V
T
I
S
I
G
V
S
A
---
T
A
-
G
---
E
G
D
T
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
------------
65
HHSearch
66.03
36%
13
- C5 -
-
2V0N
5
PLED_CAUCN
A:
[285-459]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
L
A
V
T
---
D
Q
L
T
G
L
H
N
R
R
Y
M
T
G
----
Q
L
D
-----
S
L
V
K
R
A
T
L
G
G
D
----
P
----
V
----
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
T
F
G
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
-
R
A
I
D
L
P
C
R
Y
G
G
E
E
F
V
V
I
M
P
D
T
A
L
A
D
A
L
R
I
A
E
R
I
R
M
--
H
V
S
G
S
P
F
-
T
V
A
H
-
G
-
R
E
---
M
L
N
V
T
I
S
I
G
V
S
A
---
T
A
G
E
---
G
D
T
-
P
E
A
L
-
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
G
R
N
A
V
V
G
K
A
A
H
H
H
H
H
H
-
52
HHSearch
65.80
37%
11
* C5 *
-
3IGN
2
?
A:
[5-170]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
L
S
M
T
---
D
R
L
T
G
L
L
N
R
G
T
W
E
N
----
L
V
D
-----
A
E
Y
E
R
F
R
R
Y
G
Q
----
A
----
T
----
S
L
V
M
F
D
I
D
H
F
K
P
V
N
D
T
Y
G
H
L
A
G
D
E
V
I
R
H
T
A
D
V
T
R
N
N
I
-
R
Q
S
D
S
A
G
R
Y
G
G
E
E
F
G
I
I
L
P
E
T
D
A
E
S
A
R
V
I
C
E
R
I
R
E
--
A
I
E
K
S
T
V
-
S
T
---
S
-
A
G
---
D
I
Q
Y
T
V
S
M
G
I
A
Q
---
L
T
E
T
---
P
E
N
-
Y
M
Q
W
-
M
Q
K
A
D
E
A
L
Y
K
A
K
E
S
G
R
N
K
V
V
V
S
L
--------
63
HHSearch
64.03
34%
19
- C5 -
-
3I5C
4
GCN4_YEAST
B:
[24-198]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
L
K
K
L
V
N
S
---
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
-----
M
E
W
R
R
SLRE
Q
S
----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
Q
P
-
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
---
L
V
-
P
GGG
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
Q
-------
49
HHSearch
63.71
31%
-28
- C5 -
-
3TVK
4
YDEH_ECOLI
A:
[3-168]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
N
M
---
D
V
L
T
G
L
P
G
R
R
V
L
D
E
----
S
F
D
-----
H
Q
L
R
N
AE--
P
L
----
N
----
L
----
Y
L
M
L
L
D
I
D
R
F
K
L
V
N
D
T
Y
G
H
L
I
G
D
V
V
L
R
T
L
A
T
Y
L
A
S
W
T
-
R
D
Y
E
T
V
Y
R
Y
G
G
E
E
F
I
I
I
V
K
A
A
N
D
E
E
A
C
R
A
G
V
R
I
C
Q
--
L
V
D
N
H
A
I
-
T
H
---
S
-
E
G
---
H
I
N
I
T
V
T
A
G
V
S
R
---
A
F
-
P
---
E
E
P
-
L
D
V
V
-
I
G
R
A
D
R
A
M
Y
E
G
K
Q
T
G
R
N
R
C
M
F
I
D
E
Q
N
V
I
---
64
HHSearch
63.35
34%
20
- C5 -
-
3I5C
4
GCN4_YEAST
A:
[24-196]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
L
K
K
L
V
N
S
---
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
-----
M
E
W
R
R
S
L
R
E
Q
S
----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
Q
P
-
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
---
L
V
-
P
GGG
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
---------
66
HHSearch
63.15
34%
14
- C5 -
-
3I5B
2
?
A:
[3-170]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
S
---
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
-----
M
E
W
R
R
S
L
R
E
Q
S
----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
Q
P
-
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
---
L
V
-
P
GGG
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
--------
10
PsiBlast_PDB
61.93
35%
23
- C5 -
-
3I5B
2
?
A:
[6-170]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
M
E
W
R
R
S
L
R
E
Q
----
S
-----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
-
Q
P
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
L
VP
G
G
-
G
---
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
--------
28
PsiBlast_CBE
61.29
35%
26
- C5 -
-
3BRE
2
?
B:
[167-339]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
R
L
M
N
S
---
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
M
E
W
R
R
S
L
R
E
Q
----
S
-----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
-
Q
P
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
L
VP
G
G
-
G
---
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
Q
-------
19
PsiBlast_PDB
61.19
31%
17
- C5 -
-
3I5A
2
?
A:
[165-331]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
R
L
M
N
S
---
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
L
E
W
R
-
R
A
T
R
D
----
Q
A
----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
A
Y
N
D
N
F
G
H
L
E
G
D
E
A
L
R
Q
V
A
K
A
I
R
N
S
C
S
R
P
S
D
L
P
A
R
Y
G
G
E
E
F
A
M
V
L
P
N
T
S
P
G
G
A
R
L
L
A
E
K
L
R
Q
--
S
V
A
G
M
N
I
-
P
H
-
I
-
A
-
P
V
PGS
S
L
T
V
S
I
G
V
A
T
V
T
---
P
Q
-
V
---
G
Q
H
-
S
R
Q
L
-
I
L
D
A
D
K
G
L
Y
L
A
K
N
N
G
R
N
Q
V
------------
29
PsiBlast_CBE
61.14
34%
34
- C5 -
-
3I5C
4
GCN4_YEAST
B:
[10-198]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
L
S
K
N
Y
H
L
E
N
E
V
A
R
L
K
K
L
VNS
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
MEWRR
S
L
R
E
Q
----
S
-----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
-
Q
P
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
LVP
G
G
-
G
---
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
E
Q
-------
9
PsiBlast_PDB
61.04
34%
30
- C5 -
-
3I5C
4
GCN4_YEAST
A:
[10-196]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
L
S
K
N
Y
H
L
E
N
E
V
A
R
L
K
K
L
VNS
D
G
L
T
G
L
S
N
R
R
H
F
D
E
----
Y
L
E
M
E
W
R
R
S
L
R
E
Q
----
S
-----
Q
----
L
----
S
L
L
M
I
D
V
D
Y
F
K
S
Y
N
D
T
F
G
H
V
A
G
D
E
A
L
R
Q
V
A
G
A
I
R
E
G
C
S
R
S
S
D
L
A
A
R
Y
G
G
E
E
F
A
M
V
L
P
G
T
S
P
G
G
A
R
L
L
A
E
K
V
R
R
--
T
V
E
S
L
Q
I
-
S
H
-
D
-
Q
P
R
P
---
G
S
H
L
T
V
S
I
G
V
S
T
L
VP
G
G
-
G
---
G
Q
T
-
F
R
V
L
-
I
E
M
A
D
Q
A
L
Y
Q
A
K
N
N
G
R
N
Q
V
G
L
M
---------