@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VP68: (2017-11-20 )
MGRNGSGKSNVLEALVAIFRNLDLGEAPPFSYKLTYRLGEPHKMNQPSDRWMEITIDADPERGTLAKQYEVHIRDLLNNEKQKDMFNETPSDVIIPFSKVKRDKDGKAPYLPNYVFAYYSGPSDRLEKYFKKHRTDFYRKLLKDEINLRGDIRPLFYAKPNHSQFVLLAFFLSEKDSEERAFLREHLGIEGLDSIHFVMRQPEWAKKKEELFWGAHGVVRQFLDELIQHTLSPIKVTRQEDTSLTGNNIRNEFFHLFLPNVEALRAFAKNLTADELFKMLESTLLSEIISEVNIRVKVSSSEAPLTFRELSEGEQQLLTVLGLLKFTGGKDSLFLLDEPDTHLNPSWAVKYLKFLRKFVPNHEASHLLMVTHHPLAIAELEKEQVQVMKRDDKNLISANMPDENPRGMGINLILRSDMFGLKTTLDDDTNQRLANRNALAAKETLSEEKIVREHGFPPEDEEQYLARLNSELEELGFNLATDDPDYLDFLRNKYHVKHEESN
Atome Classification :
(20 SA)
---.........10........20.......-.30..--......40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210......--.220.......230.......240......-----.--------250..-.....260.-......270-.---.......-280.......-----290.......300.......310.......320-.......----..330.....-..340.......350.......360.......370........380.......390.......400.....-..410.......420....--...430.......440.----......450.......460-.........470.......480.....----..490.......500
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---MGRNGS
G
K
S
N
V
L
E
A
L
V
A
I
F
RNLDLGEAP-P
F
S
Y
K
--
L
T
Y
RLGEPHKMNQPSD
R
W
M
E
I
T
I
DADPERGT
L
A
K
Q
Y
E
V
H
I
R
D
L
LN
N
E
K
Q
K
D
M
FNETPS
D
V
I
IP
F
S
K
VKRDKDGKAPYLP
N
Y
V
F
A
Y
YSG
P
S
D
R
L
E
K
Y
F
K
K
H
R
T
D
F
Y
R
K
L
L
K
D
E
INLRGDI
R
P
L
F
Y
AKPNHS
Q
F
V
L
L
A
F
F
LSEKD
S
E
E
R
A
F
L
R
E
H
LGIEG
L
D
S
I
H
F
V
MRQ
P
E
W
A
K
K
K
E
E
L
F
WG
A
H
G
V
--
V
R
Q
F
L
D
E
L
I
Q
HTLSP
I
K
V
TRQEDTSLTGN
N
-----
I
--------
R
N
E
F
F
-
H
L
FLP
N
V
E
A
-
L
R
A
F
A
KNL--
T
---
A
D
E
L
F
K
M
-
L
E
S
T
L
L
S
E
I
I
-----
S
EV
N
I
R
V
K
VSSSEA
P
L
T
F
R
E
LSE
G
E
Q
Q
L
L
T
V
---
L
G
L
L
KFT----GGK
D
S
L
F
L
LD-EPDTHL
N
P
S
W
A
V
K
Y
L
K
F
L
R
K
FVPNHEA
S
H
L
L
M
V
-THHP
L
A
I
A
E
L
E
K
E
Q
V
Q
V
M
KRDDKNLISANMPDENPRG-
M
G
I
N
L
I
L
RSDMFGLKTTLD--DDT
N
Q
R
LANRNAL
A
A
K
E
----TL
S
E
E
K
I
V
R
EHGFPP
E
D
---
E
E
Q
Y
L
A
R
L
N
S
E
L
E
E
LGFNLATDD
P
D
Y
L
----
D
F
L
R
NK
Y
H
V
KHEESN
42
HHSearch
59.52
17%
-
- C3 -
-
4RFS
-
ECFA1_LACBA
B:
[19-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
P
A
L
T
D
V
S
F
T
V
H
A
G
E
W
L
A
I
V
G
H
N
--
G
S
-
G
K
S
T
L
A
K
S
L
D
G
L
L
P
F
T
Q
G
S
V
T
V
G
G
I
T
L
T
P
E
T
V
W
Q
-----
V
R
E
Q
I
G
---
M
I
F
Q
N
P
D
N
Q
F
V
G
A
T
V
-
E
D
D
V
A
F
G
L
--
E
---
N
R
Q
I
S
R
D
-
E
M
V
P
R
V
Q
A
A
L
-----
A
Q
V
G
M
T
S
-----
F
A
Q
R
E
P
S
S
L
S
G
G
Q
K
Q
R
V
A
L
------
A
G
I
V
----
A
I
A
P
K
I
L
I
L
D
-
E
A
T
S
M
L
D
P
Q
G
R
I
E
M
L
A
I
V
R
Q
L
R
Q
-
Q
Q
N
L
T
V
I
S
I
-
T
H
D
I
D
E
A
A
S
A
--
D
R
V
L
V
I
D
D
---
G
R
L
V
D
E
A
V
P
S
Q
----------------------------------------------------------------------------------------------------------------
43
HHSearch
59.41
17%
-
- C3 -
-
4HUQ
-
ECFA1_LACBA
B:
[19-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
P
A
L
T
D
V
S
F
T
V
H
A
G
E
W
L
A
I
V
G
H
N
--
G
S
-
G
K
S
T
L
A
K
S
L
D
G
L
L
P
F
T
Q
G
S
V
T
V
G
G
I
T
L
T
P
E
T
V
W
Q
-----
V
R
E
Q
I
G
---
M
I
F
Q
N
P
D
N
Q
F
V
G
A
T
V
-
E
D
D
V
A
F
G
L
--
E
---
N
R
Q
I
S
R
D
-
E
M
V
P
R
V
Q
A
A
L
-----
A
Q
V
G
M
T
S
-----
F
A
Q
R
E
P
S
S
L
S
G
G
Q
K
Q
R
V
A
L
------
A
G
I
V
----
A
I
A
P
K
I
L
I
L
D
-
E
A
T
S
M
L
D
P
Q
G
R
I
E
M
L
A
I
V
R
Q
L
R
Q
-
Q
Q
N
L
T
V
I
S
I
-
T
H
D
I
D
E
A
A
S
A
--
D
R
V
L
V
I
D
D
---
G
R
L
V
D
E
A
V
P
S
Q
----------------------------------------------------------------------------------------------------------------
34
HHSearch
53.97
13%
-
* C3 *
-
4TQV
-
?
G:
[16-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
--
G
C
-
G
K
ST
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
G
R
V
I
N
D
L
A
P
K
D
RDV--
A
--------
M
V
F
Q
N
-
Y
A
L
Y
P
H
L
N
V
-
R
D
N
I
S
F
G
L
--
R
---
L
K
R
T
K
K
S
-
V
I
D
A
A
V
K
T
A
A
-----
D
I
L
G
L
Q
P
-----
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
------
G
R
A
I
----
V
R
D
P
K
V
F
L
F
D
-
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
-
R
L
G
T
T
V
I
Y
V
-
T
H
D
Q
V
E
A
M
T
L
-
A
D
R
I
V
V
M
R
D
---
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
-
H
P
----------------------------------------------------------------------------------------------------------
29
Fugue
48.83
18%
58
- C2 -
-
1NI3
-
OLA1_SCHPO
A:
[11-388]
K
V
Q
W
G
R
P
G
N
--------------
N
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
V
L
G
N
P
A
N
Y
P
Y
A
T
I
----
D
P
E
E
A
K
V
A
V
------------------------------------------------------
P
D
E
R
F
D
W
L
C
E
A
Y
K
P
K
---
S
R
V
P
A
F
L
T
V
F
-
D
I
A
G
L
T
K
G
A
-------------
S
T
G
V
G
L
G
N
A
F
L
S
H
---
V
R
A
V
D
A
I
Y
Q
V
V
R
----------------------------
A
F
D
D
A
E
I
I
H
V
E
G
D
V
D
P
I
R
D
L
S
I
-----
I
--------
V
D
E
L
L
-
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
T
--
S
---
R
G
A
N
T
L
E
M
K
A
K
K
E
E
Q
A
I
I
-----
E
K
V
Y
Q
Y
L
T
--
E
T
K
Q
P
I
R
K
G
D
W
S
N
R
E
V
E
I
I
N
S
---
L
Y
L
L
T
A
-------
K
P
V
I
Y
L
V
N
M
S
E
R
D
F
L
R
Q
K
N
--
K
Y
L
P
K
I
K
K
W
I
D
E
N
S
P
G
D
T
L
I
P
M
S
------
V
A
F
E
E
R
L
T
N
F
T
E
E
E
A
I
E
E
C
K
K
L
----
N
T
K
S
M
L
P
K
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
V
R
S
W
T
I
R
K
G
T
K
A
P
Q
----
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
MESG
D
I
A
H
W
K
---------
37
HHSearch
48.24
14%
-
- C3 -
-
5C73
-
PGLK_CAMJE
A:
[362-562]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Y
L
F
K
N
L
N
L
N
I
K
K
G
E
K
I
A
F
I
G
E
S
--
G
C
-
G
K
ST
L
V
D
L
I
I
G
L
L
K
P
K
E
G
Q
I
L
I
D
K
Q
E
L
N
A
S
N
A
K
N
-----
Y
RQK
I
G
---
Y
I
P
Q
N
-
I
Y
L
F
-
N
D
S
I
-
A
K
N
I
T
F
G
D
AV
D
---
E
E
K
L
N
K
V
-
I
K
Q
A
N
L
E
H
F
I
-----
K
N
L
P
Q
G
V
Q
T
---
K
V
G
D
G
G
S
N
L
S
G
G
Q
K
Q
R
I
A
I
------
A
R
A
L
----
Y
L
E
P
E
I
L
V
L
D
-
Q
A
T
S
A
L
D
T
Q
S
E
A
K
I
M
D
E
I
Y
K
I
S
K
---
D
K
T
M
I
I
I
-
A
H
R
L
S
T
I
T
Q
C
--
D
K
V
Y
R
L
E
H
---
G
K
L
K
E
----------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
47.68
26%
-114
- C3 -
-
3AUY
-
?
A:
[267-345]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
V
H
A
P
N
G
V
L
T
I
D
N
L
S
G
G
E
Q
I
A
V
A
L
---
S
L
R
L
A
I
A
N
A
L
I
G
N
R
V
E
C
I
I
L
D
-
E
P
T
V
Y
L
D
E
N
R
R
A
K
L
A
E
I
F
R
K
V
---
K
S
I
P
Q
M
I
I
I
-
T
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
46.53
17%
25
- C3 -
-
3NHB
2
A:
[67-274]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
T
L
Q
D
V
S
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
--
G
A
-
G
K
S
T
I
L
R
L
L
F
R
F
Y
D
I
S
S
G
C
I
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
-----
L
R
S
H
IG---
V
V
P
Q
D
-
T
V
L
-
F
N
D
T
I
-
A
D
N
I
R
Y
G
R
--
V
TAG
N
D
E
V
E
A
A
-
A
Q
A
A
G
I
H
D
A
I
-----
M
A
F
P
E
G
Y
R
T
---
Q
V
G
E
R
G
L
K
L
S
G
G
E
K
Q
R
V
A
I
------
A
R
T
I
----
L
K
A
P
G
I
I
L
L
D
-
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
S
L
A
K
V
C
A
---
N
R
T
T
I
V
V
-
A
H
R
L
S
T
V
V
N
--
A
D
Q
I
L
V
I
K
D
---
G
C
I
V
E
R
G
R
H
E
A
----------------------------------------------------------------------------------------------------------------
44
HHSearch
45.60
17%
19
- C3 -
-
3NH6
2
A:
[67-274]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
T
L
Q
D
V
S
F
T
V
M
P
G
Q
T
L
A
L
V
G
P
S
--
G
A
-
G
K
S
T
I
L
R
L
L
F
R
F
Y
D
I
S
S
G
C
I
R
I
D
G
Q
D
I
S
Q
V
T
Q
A
S
L
R
S
H
I
G
--------
V
V
P
Q
D
-
T
V
L
-
F
N
D
T
I
-
A
D
N
I
R
Y
G
R
--
V
TAG
N
D
E
V
E
A
A
-
A
Q
A
A
G
I
H
D
A
I
-----
M
A
F
P
E
G
Y
R
T
---
Q
V
G
E
R
G
L
K
L
S
G
G
E
K
Q
R
V
A
I
------
A
R
T
I
----
L
K
A
P
G
I
I
L
L
D
-
E
A
T
S
A
L
D
T
S
N
E
R
A
I
Q
A
S
L
A
K
V
C
A
---
N
R
T
T
I
V
V
-
A
H
R
L
S
T
V
V
N
--
A
D
Q
I
L
V
I
K
D
---
G
C
I
V
E
R
G
R
H
E
A
----------------------------------------------------------------------------------------------------------------
45
HHSearch
44.91
18%
7
- C3 -
-
3DHW
-
METN_ECOLI
C:
[18-227]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
--
G
A
-
G
K
ST
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
-----
L
TKARRQIG
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
-
F
G
N
V
A
L
P
L
--
E
---
L
D
N
T
P
K
D
-
E
V
K
R
R
V
T
E
L
L
-----
S
L
V
G
L
G
D
-----
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
------
A
R
A
L
----
A
S
N
P
K
V
L
L
C
D
-
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
G
L
T
I
L
L
I
-
T
H
E
M
D
V
V
K
R
I
-
C
D
C
V
A
V
I
S
N
---
G
E
L
I
E
Q
D
T
V
S
E
----------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
44.44
26%
-91
- C3 -
-
3AV0
3
B:
[267-345]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
V
H
A
P
N
G
V
L
T
I
D
N
L
S
G
G
E
Q
I
A
V
A
L
---
S
L
R
L
A
I
A
N
A
L
I
G
N
R
V
E
C
I
I
L
D
-
E
P
T
V
Y
L
D
E
N
R
R
A
K
L
A
E
I
F
R
K
V
---
K
S
I
P
Q
M
I
I
I
-
T
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
43.82
26%
-110
- C3 -
-
5F3W
2
B:
[268-346]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
V
H
A
P
N
G
V
L
T
I
D
N
L
S
G
G
E
Q
I
A
V
A
L
---
S
L
R
L
A
I
A
N
A
L
I
G
N
R
V
E
C
I
I
L
D
-
E
P
T
V
Y
L
D
E
N
R
R
A
K
L
A
E
I
F
R
K
V
---
K
S
I
P
Q
M
I
I
I
-
T
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
43.69
16%
31
- C3 -
-
1Z47
-
?
B:
[27-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
--
G
S
-
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
T
D
L
P
P
Q
K
RN
V
--
G
--------
L
V
F
Q
N
-
Y
A
L
F
Q
H
M
T
V
-
Y
D
N
V
S
F
G
L
--
R
---
E
K
R
V
P
K
D
-
E
M
D
A
R
V
R
E
L
L
-----
R
F
M
R
L
E
S
-----
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
------
A
R
A
L
----
A
P
R
P
Q
V
L
L
F
D
-
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
-
E
M
G
V
T
S
V
F
V
-
T
H
D
Q
E
E
A
L
E
V
-
A
D
R
V
L
V
L
H
E
---
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
-
K
-----------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
43.55
26%
-53
- C3 -
-
4NCJ
1
A:
[209-312]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
E
I
F
A
E
-
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
E
R
P
L
T
F
--
L
S
G
G
E
R
I
A
L
G
L
A
F
E
L
A
M
S
L
Y
L
----
A
G
E
I
S
L
L
I
L
D
-
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
R
Y
L
K
--
K
I
P
Q
V
I
L
V
-
S
H
------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
43.33
26%
-112
- C3 -
-
5DNY
2
?
B:
[267-345]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
V
H
A
P
N
G
V
L
T
I
D
N
L
S
G
G
E
Q
I
A
V
A
L
---
S
L
R
L
A
I
A
N
A
L
I
G
N
R
V
E
C
I
I
L
D
-
E
P
T
V
Y
L
D
E
N
R
R
A
K
L
A
E
I
F
R
K
V
---
K
S
I
P
Q
M
I
I
I
-
T
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
42.43
26%
-107
- C3 -
-
3AUX
-
A:
[267-345]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
V
H
A
P
N
G
V
L
T
I
D
N
L
S
G
G
E
Q
I
A
V
A
L
---
S
L
R
L
A
I
A
N
A
L
I
G
N
R
V
E
C
I
I
L
D
-
E
P
T
V
Y
L
D
E
N
R
R
A
K
L
A
E
I
F
R
K
V
---
K
S
I
P
Q
M
I
I
I
-
T
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
40.88
26%
-
- C- -
-
4NCI
-
?
A:
[752-855]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
E
I
F
A
E
-
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
E
R
P
L
T
F
--
L
S
G
G
E
R
I
A
L
G
L
A
F
E
L
A
M
S
L
Y
L
----
A
G
E
I
S
L
L
I
L
D
-
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
R
Y
L
K
--
K
I
P
Q
V
I
L
V
-
S
H
------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.32
26%
-54
- C3 -
-
3QKT
2
A:
[209-312]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
E
I
F
A
E
-
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
E
R
P
L
T
F
--
L
S
G
G
E
R
I
A
L
G
L
A
F
R
L
A
M
S
L
Y
L
----
A
G
E
I
S
L
L
I
L
D
-
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
R
Y
L
K
--
K
I
P
Q
V
I
L
V
-
S
H
------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
40.17
13%
24
- C3 -
-
4TQU
-
?
T:
[16-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
--
G
C
-
G
K
ST
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
G
R
V
I
N
D
L
A
P
K
D
RDV--
A
--------
M
V
F
Q
N
-
Y
A
L
Y
P
H
L
N
V
-
R
D
N
I
S
F
G
L
--
R
---
L
K
R
T
K
K
S
-
V
I
D
A
A
V
K
T
A
A
-----
D
I
L
G
L
Q
P
-----
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
------
G
R
A
I
----
V
R
D
P
K
V
F
L
F
D
-
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
-
R
L
G
T
T
V
I
Y
V
-
T
H
D
Q
V
E
A
M
T
L
-
A
D
R
I
V
V
M
R
D
---
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
-
H
P
A
N
T
F
V
-
A
S
F
I
G
-----------------------------------------------------------------------------------------------
25
Fugue
39.14
14%
-
* C1 *
-
3TW8
-
DEN1B_HUMAN
A:
[2-374]
---
M
D
C
------------------------------------------
R
T
K
A
N
P
D
R
T
F
D
L
V
L
K
V
K
C
E
D
P
V
V
L
W
K
F
P
E
D
F
G
D
-----------------------------
Q
E
I
L
Q
S
V
P
K
F
C
F
P
F
D
------------------------------------
V
E
R
V
S
Q
N
Q
V
G
Q
H
F
T
F
V
L
T
D
I
E
S
K
Q
R
F
G
F
C
R
L
T
--
S
G
G
T
I
C
L
C
I
L
S
Y
L
P
W
F
E
V
Y
Y
K
L
L
N
T
L
A
D
Y
--
L
A
K
E
L
E
N
D
L
N
E
T
L
R
S
L
Y
N
H
P
V
P
K
A
N
T
G
L
P
T
-----
I
------------------
P
E
S
R
N
-
L
T
E
Y
F
V
A
V
--
D
---
V
N
N
M
L
Q
L
-
Y
A
S
M
L
H
E
R
------------
R
I
V
I
I
S
S
K
----
L
S
T
L
T
A
C
I
H
G
S
A
A
L
---
L
Y
P
M
Y
W
------------------
Q
H
I
Y
I
P
V
L
P
P
H
L
L
D
Y
C
C
A
P
M
P
-----
Y
L
I
G
I
-
H
S
S
L
I
E
R
V
K
N
K
S
L
E
D
V
V
M
L
N
V
D
T
N
T
L
E
S
P
F
S
D
L
N
N
L
P
-
S
D
V
V
S
A
L
K
N
K
L
K
K
Q
S
T
A
T
G
--
D
G
V
A
R
A
F
L
R
A
Q
A
A
L
F
G
S
YRDI
T
F
C
E
E
S
F
V
K
H
---
R
S
S
V
---
M
K
Q
F
L
E
T
A
I
N
----------------
L
----
Q
L
F
K
Q
F
I
D
G
R
L
A
K
L
N
7
PsiBlast_PDB
38.51
26%
-59
- C3 -
-
1II8
-
?
B:
[44-147]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
E
I
F
A
E
-
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
E
R
P
L
T
F
--
L
S
G
G
E
R
I
A
L
G
L
A
F
R
L
A
M
S
L
Y
L
----
A
G
E
I
S
L
L
I
L
D
-
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
R
Y
L
K
K
--
I
P
Q
V
I
L
V
-
S
H
------------------------------------------------------------------------------------------------------------------------------------------------