@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQ75: (2017-11-25 )
MHPYAPTLQRVLLFGLFFILIFLGFNILKYFIVPVLWAAIIAYMTWPIYLRIQHFFGENRNNLNATVMISLVILIVGVPFTCAIFILQHEGRNLYFDLQRQVFSGHLSVPDFIRNLPFIGKEISRTLNEINTDPNSTIQNIAAWVQSHLSYGRVLLNEISKNIVKLCFAILSLFFFYRDGHTILTQVSKALEMVIGPRIHHYLDTISETTRAVVYGVGLTAIAQAVLAGLSYFVAGVPNPMVLTIATFLLALIPFGTPVSYLGVGLWLFSQGQTMEAIGVILWGVLIVSSSDNVIRPLVISGATQIPFLLIMFGVLGGIASFGLVGLFIGPVILAVLLAIWREWLHETIDPEPMPKTTMIYDSDDDLPPSKN
Atome Classification :
(18 SA)
------------------------------------------------------------.........10.-.......20.-.......30........40.......---.50...-----------..----...----60........70........80----------.....----------------------....90.--.......100-----..-..---...110.......120....--------...130.......140.---......-150.......------160....-------...170......-.180.......190...---.---.-..200------........210.......220.......230---.........240.......250.......260.......270--------.........280.-......290.......300.......310.......320.......330.......340---------------.........350.......360.......370-------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------MHPY
A
P
T
L
Q
R
V
L
-
L
F
G
L
F
F
I
L
I
F
-
L
G
F
N
I
L
K
Y
F
I
V
P
V
L
W
A
A
I
I
A
YMTW
P
I
---
Y
L
R
I
Q
H
-----------
F
F----GEN----RNNL
N
A
T
V
M
I
S
L
V
I
L
I
VG
V
P
F
-----------
T
C
A
I
F
----------------------
I
L
QHEGR--
N
L
Y
F
D
L
Q
R
Q
V
-----FS-GH---LSV
P
D
F
I
R
NLPF
I
G
K
E
I
S
R
T
--------
L
N
E
INTDP
N
S
T
I
Q
N
I
A
A
---
W
V
Q
S
H
L
-
S
Y
G
R
V
L
L
N
E
I
------
S
K
N
I
V
K
L
-------
C
F
A
I
L
S
L
F
F
F
YR-D
G
H
T
I
L
T
Q
V
S
K
A
L
E
M
V
I---G---
P
-
R
I
H
H
-------
Y
L
D
T
I
S
E
T
T
R
A
V
V
YGV
G
L
T
A
I
A
Q
A
V
L
A
G
L
-----
S
Y
F
V
AGVPN
P
M
V
L
T
I
A
T
F
L
L
A
L
IPFGT
P
V
S
Y
L
G
V
G
L
WLFS----------QG
Q
T
M
E
A
I
G
V
I
L
W
-
G
V
L
I
VSSSDN
V
I
R
P
L
V
ISGATQ
I
P
F
L
L
I
M
F
G
V
L
G
G
I
A
S
F
G
L
V
G
L
F
I
G
P
V
I
L
A
V
L
L
A
I
-----------------
W
R
E
W
L
H
ETIDPEPMP
K
T
T
M
I
YDSDDDLPPSKN-------------------------
15
Fugue
72.78
18%
-113
- C2 -
-
5T77
15
MURJ_THEAB
A:
[4-470]
--------------------------------------------------------------
L
F
S
S
I
L
F
S
I
A
-
T
F
F
S
R
I
L
G
L
F
-
R
D
V
L
F
A
K
Y
F
G
V
S
Y
E
L
D
A
Y
F
I
A
I
M
F
P
F
---
F
L
R
K
V
F
G
E
G
A
M
S
S
A
F
V
P
L
Y
S
E
KS
G
E
E
----
K
D
K
F
L
S
S
V
I
N
G
F
S
L
I
I
L
A
L
V
I
-----------
L
S
Y
F
F
P
E
L
I
I
N
L
F
GAGSS
H
E
T
K
I
L
A
K
K
L
L
L
I
T
S
P
--
S
I
Y
F
I
F
L
W
A
I
-----
S
Y
-
S
I
---
L
N
T
N
N
K
F
-
F
W
P
A
L
T
P
S
I
S
N
I
--------
T
I
I
I
G
T
F
L
-
S
T
K
Y
G
I
I
S
---
P
T
I
G
F
L
-
I
G
S
I
L
M
F
F
S
I
------
I
K
S
I
I
K
H
K
Y
Y
FTIK
H
F
P
H
F
L
K
L
F
F
P
T
-
F
M
T
M
V
V
S
Q
I
N
T
V
V
D
M
N
V
---
V
S
FY
D
-
K
G
S
I
-------
S
Y
L
Q
Y
A
S
R
F
Y
L
L
P
Y
G
L
F
A
V
S
V
S
T
V
V
L
S
K
I
-----
S
N
D
R
K
N
F
N
Y
H
L
N
D
A
L
K
T
T
L
F
F
T
I
P
S
M
V
G
L
I
F
L
S
T
P
I
I
R
F
F
YEHGAFT
S
K
D
T
L
I
T
S
K
I
L
I
A
Y
T
L
-
G
L
P
F
Y
G
I
Y
S
T
I
S
R
S
Y
H
A
I
K
N
T
K
T
P
F
I
A
A
T
I
V
S
L
S
N
I
I
L
D
I
I
F
G
L
K
Y
G
P
I
G
V
A
L
A
T
S
I
A
G
I
I
G
V
L
Y
L
L
F
S
VKTFP
I
K
D
F
L
K
I
S
L
N
S
L
I
M
L
F
V
I
Y
L
T
D
F
T
D
N
E
F
W
F
L
I
Q
I
L
I
G
I
L
V
Y
L
I
F
S
S
I
F
Y
R
D
L
I
R
R
F
L
18
Fugue
64.00
16%
-127
- C2 -
-
4RP9
8
ULAA_ECOLI
A:
[6-456]
NIFTVFFNQVMTN
A
P
L
L
L
G
I
V
T
C
L
G
Y
I
L
L
RKS
V
S
V
I
I
K
G
T
I
K
T
I
I
G
F
M
L
L
Q
A
G
S
G
I
L
T
S
T
F
K
P
V
V
A
K
M
S
E
V
Y
G
I
N
G
A
I
S
D
T
Y
A
-
S
M
M
A
T
I
D
R
M
G
D
A
Y
S
W
V
G
Y
A
V
L
L
A
L
A
L
N
I
C
Y
V
L
L
R
R
-----------
I
T
----
G
I
R
----
T
I
M
L
T
G
H
I
M
F
Q
Q
A
G
L
I
A
V
T
L
F
I
F
GYS
M
W
T
T
I
I
C
T
A
I
L
----------------------
V
S
L
Y
W
G
I
T
S
N
M
M
Y
K
P
T
Q
E
V
T
DGCG
F
S
I
G
H
QQ
Q
F
A
S
W
I
A
Y
K
V
A
P
F
L
G
K
K
E
E
S
V
E
D
L
K
L
P
G
W
L
N
I
F
H
D
N
I
V
S
T
A
I
V
M
T
I
---
F
F
G
A
I
L
L
S
F
G
I
D
T
V
Q
A
M
A
GKVH
W
T
V
Y
I
L
Q
T
-------
G
F
S
F
A
V
A
I
F
I
I
T
-
Q
G
V
R
M
F
V
A
E
L
S
E
A
F
N
G
I
---
S
---
Q
-
R
L
I
P
G
A
V
L
A
I
D
C
A
A
I
Y
S
F
A
P
N
A
V
V
W
G
F
M
W
G
T
I
G
Q
L
I
A
V
G
I
-----
L
V
A
C
-
G
S
S
I
L
I
I
P
G
F
I
P
M
F
F
S
N
A
T
I
G
V
F
A
N
H
F
G
--
G
W
R
A
A
----------
L
K
I
C
L
V
M
G
M
I
E
I
F
-
G
C
V
W
A
V
K
L
T
G
-------------------
M
S
A
W
M
G
M
A
D
W
S
I
----
L
A
P
P
M
M
Q
G
F
F
S
I
-----------------
G
I
A
F
M
A
V
I
I
V
---
I
A
L
A
Y
M
F
F
A
G
R
A
L
R
A
E
E
D
A
-------------------------
4
PsiBlast_PDB
48.51
25%
-
- C2 -
-
3B5W
-
MSBA_ECOLI
A:
[54-161]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
F
G
K
T
D
R
S
V
L
V
W
M
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
V
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
L
F
G
H
M
-
M
G
M
P
V
S
F
-------
F
D
----------
K
Q
S
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
F
-----------------------------------------------------------------------------------------------------
22
Fugue
47.32
17%
-233
- C2 -
-
2OO2
-
?
A:
[0-75]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
E
E
E
L
---
R
---
R
-
E
T
L
K
-------
W
L
E
R
I
E
E
R
V
K
E
I
E
G
D
E
G
F
M
R
N
I
E
A
Y
I
S
D
S
-----
R
Y
F
L
E
K
G
D
L
V
R
A
F
E
C
V
V
W
A
W
A
W
L
E
I
G
L
E
V
G
K
L
H
E
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
44.27
11%
-43
- C2 -
-
1RP3
-
?
A:
[0-234]
----------------------------------------------------------HM
K
N
P
Y
S
N
Q
I
E
R
E
E
-
L
I
L
K
Y
L
P
L
V
K
A
I
A
T
N
I
K
K
H
L
P
E
D
V
D
I
R
D
L
I
S
Y
G
V
I
G
L
---
I
K
A
V
D
N
-----------
L
S
----
T
E
N
P
K
R
A
E
A
Y
I
K
L
R
I
K
G
A
I
Y
D
Y
L
R
S
L
D
F
-----------
G
S
R
Q
V
----------------------
R
E
K
E
R
R
I
--
K
E
V
V
E
K
L
K
E
K
-----
L
G
-
R
E
---
P
T
D
E
E
V
A
K
E
L
G
I
S
T
E
E
L
F
K
T
--------
L
D
K
I
N
F
S
Y
I
L
S
L
E
E
V
F
R
---
D
F
A
R
D
Y
-
S
E
L
I
P
S
S
T
N
V
------
E
E
E
V
I
K
R
-------
E
L
T
E
K
V
K
E
A
V
-----
S
K
L
P
E
R
E
K
L
V
I
Q
L
I
F
---
Y
---
E
E
L
P
A
K
-------
E
V
A
K
I
L
E
T
S
V
S
R
V
S
Q
L
K
A
K
A
L
E
R
L
R
E
M
L
S
-----
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
35.86
20%
-83
- C2 -
-
1NYH
-
SIR4_YEAST
A:
[1271-1346]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
F
V
D
I
V
-----
L
S
-
K
A
---
A
S
A
L
D
E
K
E
K
Q
L
A
V
A
N
E
I
I
R
S
--------
L
S
D
E
V
M
R
N
E
I
R
I
T
S
L
Q
G
D
L
T
F
T
K
K
C
L
-
E
N
A
R
S
Q
I
S
E
K
------
D
A
K
I
N
K
L
-------
M
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
32.67
12%
-160
* C2 *
-
5CMZ
-
?
B:
[2-33]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
W
E
E
W
D
K
K
--------
I
E
E
L
I
K
K
S
E
E
L
I
K
K
I
E
E
---
Q
I
K
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
32.59
14%
-100
- C2 -
-
1WWU
-
A:
[1-99]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
S
S
G
F
R
V
E
R
S
Q
--------
P
A
S
Q
P
L
T
Y
E
S
G
P
D
E
V
R
A
---
W
L
E
A
K
----------
A
F
------
S
P
R
I
V
E
N
---------------
L
G
I
L
-
T
G
P
Q
L
F
S
L
N
K
E
E
L
K
K
V
C
GEE
G
---
V
-
R
V
Y
S
-------
Q
L
T
M
Q
K
A
F
L
E
K
Q
Q
S
G
S
E
L
S
G
P
S
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
28.33
41%
-88
- C2 -
-
4ZXC
-
?
W:
[120-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
T
P
L
I
M
A
T
F
K
A
I
-----------------
L
R
D
W
T
N
A
T
F
D
P
F
A
A
P
E
E
T
---------------------------------------
1
PsiBlast_PDB
28.05
41%
-84
- C2 -
-
4ZXA
-
?
W:
[120-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
T
P
L
I
M
A
T
F
K
A
I
-----------------
L
R
D
W
T
N
A
T
F
D
P
F
A
A
P
E
E
T
---------------------------------------
7
HHSearch
26.69
31%
15
- C1 -
-
1SG7
-
CHAB_ECO57
A:
[22-33]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
K
T
K
S
D
L
P
E
S
V
--------------------------
3
PsiBlast_PDB
25.80
41%
-59
- C2 -
-
4ZXD
-
?
W:
[120-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
T
P
L
I
M
A
T
F
K
A
I
-----------------
L
R
D
W
T
N
A
T
F
D
P
F
A
A
P
E
E
T
---------------------------------------
5
HHSearch
20.49
28%
-101
- C2 -
-
4B19
-
?
A:
[6-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
I
I
A
P
V
I
S
G
C
A
I
A
F
-----------------
F
S
Y
W
L
S
R
R
N
T
K
----------------------------------------------
6
HHSearch
19.67
27%
-45
- C2 -
-
2KV5
-
?
A:
[7-32]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
I
A
P
I
F
V
G
L
V
L
E
M
-----------------
I
S
R
V
L
D
E
E
D
D
S
R
---------------------------------------------
17
Fugue
19.03
24%
-91
- C2 -
-
2KV5
-
?
A:
[1-33]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
D
L
M
S
L
V
I
A
P
I
F
V
G
L
V
L
E
M
-----------------
I
S
R
V
L
D
E
E
D
D
S
R
K
--------------------------------------------
9
HHSearch
15.34
10%
-54
- C2 -
-
2OAR
-
MSCL_MYCTU
A:
[95-145]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
------
L
S
A
A
I
N
F
-------
F
L
I
A
F
A
V
Y
F
L
V
V
L
P
Y
N
T
L
R
K
K
G
E
V
E
-
Q
--
P
---
G
---
D
-
T
Q
V
V
-------
L
L
T
E
I
R
D
L
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
14.07
28%
-69
- C2 -
-
5B66
-
PSBJ_THEVL
J:
[12-29]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
T
V
A
G
M
G
V
I
V
I
V
G
L
F
F
-------------------------------------------------------------------------------------
8
HHSearch
4.67
13%
85
- C2 -
-
4PX7
1
?
A:
[214-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
T
L
I
S
W
A
L
V
A
V
A
T
W
L
-----------------
A
Q
R
I
C
G
P
L
T
P
P
--
E
E
N
R
E
I
A
Q
R
E
Q
E
S
L
E
H
H
---------------------------