@TOME V2.3
(Mar 2018)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQ78: (2017-11-25 )
MRYKAMKKQRLMIALLATLGMGSAFASTSSEYNIANGLLPVEKDQSISVLQPFQGNFRILGSKIYHNDEQAKFSPIDYAVSWGLFAQPEIARHISVKQYDRYLNWKIAKLPVPAEQAMQMVSNMHIIPANPEIAQQIKQVKRGDLVYLKGDLVEIKDKDLVWKSSLTPTDIGNGACELFRVQSIHWVEKQNI
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------........------.10..-.-.....20.....-..-------.30.---------......--.40..----..-----------....-----50.-----.......-60..----------------------......70-...--.--------------------...------..---80...--------------.....90........100-.......--..-110----------------------......-----.120-....------....130-------.....-..140...---....150.--......160.---...-...170......--.180.......190-----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------MR
Y
K
A
M
K
K
------
Q
R
L
M
I
-
A
-
L
L
A
T
LGMG
S
A
FA-ST-------SSEY---------NIANGL--LPVEK----DQ-----------S
I
S
V
-----LQP-----FQG
N
F
R
I
-
L
G
S
K
----------------------IYHNDEQ--AKF--S--------------------P
I
D
------
Y
A
---
V
SWGL--------------FA
Q
P
E
I
A
R
H
I
S
V
K
Q
Y
D
---
R
YLN
W
K
I
--
A
K-LPV----------------------
P
A
E
Q
A
M
-----
Q
M
V
--SN
M
H
------IIPAN
P
E
-------
I
A
Q
Q
I
-
K
Q
VKRG
D
L
---
V
Y
LKG
D
L
V
--
E
IKDKD
L
V
WK---SSL-TPTDIGNG
A
C
E
L
--
F
R
V
Q
S
I
H
W
V
EKQNI-----------------------------
35
Fugue
73.35
21%
-
- C2 -
-
4LL1
-
TXNIP_HUMAN
A:
[7-298]
---------------------------------------------------------------------------------------------------------IK
S
F
E
V
V
F
NDPEKVYGSG
E
K
V
A
G
R
V
I
V
E
V
C
E
V
------
T
R
V
K
A
-
V
-
R
I
L
A
C
G
V
A
K
V
L
W
-
M
Q
GS
Q
Q
C
K
Q
T
S
E
Y
---------
L
R
Y
E
D
T
--
L
L
L
E
D
QPTG
E
N
-----------
E
M
V
I
-----
M
R
P
G
N
K
--
Y
E
Y
K
F
G
F
E
L
P
Q
G
----------------------
P
L
G
T
S
F
K
--
G
K
Y
--
G
--------------------
S
V
D
------
Y
W
---
V
K
A
F
L
D
R
P
SQP
T
Q
E
T
K
K
N
F
E
V
V
P
D
L
M
A
P
V
S
A
K
K
E
K
---
K
V
S
S
M
F
I
PD
G
R
-
V
S
V
----------------------
S
A
R
I
D
R
-----
K
G
F
CE
G
D
E
I
------
S
I
H
A
D
F
E
-------
N
T
S
S
R
-
I
V
V
P
K
A
A
I
---
V
A
R
H
T
Y
L
A
--
N
G
Q
T
K
V
L
T
Q
K
L
--
S
S
V
-
R
G
N
H
I
I
S
G
T
C
A
S
--
W
R
G
K
S
L
R
-
V
Q
K
I
N
I
L
R
V
E
Y
S
L
L
I
Y
V
S
V
P
GSKKV
I
L
D
L
P
L
V
I
G
S
30
Fugue
58.60
22%
49
- C7 -
-
4OBX
2
COQ5_YEAST
A:
[23-257]
------------------------------------------------------------------------------------------------------------------------------S
V
A
N
R
Y
D
L
M
N
D
V
M
S
L
GI
H
R
L
W
K
-
D
H
F
I
N
K
L
D
A
G
K
R
P
N
-
S
T
-------
T
P
L
N
F
I
D
V
AGGSG
D
I
A
F
G
L
--
L
D
H
A
E
----
S
K
FGDTE
S
T
M
D
I
V
D
I
N
P
-----
D
M
L
-----
K
E
G
E
K
R
A
-
M
E
Q
G
----------------------
K
Y
F
K
D
P
R
--
V
R
F
--
L
V
S
NGEKLE------------
E
I
D
SDSKD
I
Y
T
---
V
S
F
G
I
--------------
R
N
F
T
D
I
Q
K
G
L
N
T
A
Y
R
V
---
L
K
P
G
G
I
F
--
Y
C
-
L
E
F
S
---------------------
K
I
E
N
P
L
-----
M
D
F
--
A
Y
Q
Q
------
W
A
K
V
L
P
V
-------
M
G
S
M
I
-
A
N
-
D
Y
D
S
Y
---
Q
Y
L
V
E
S
I
E
--
R
F
P
D
-
Q
E
T
F
K
---
S
M
I
-
E
K
A
G
F
K
S
A
G
Y
E
S
L
T
F
G
I
C
A
I
H
W
G
I
K
V
-------------------------------
29
Fugue
52.93
14%
-86
* C7 *
-
3KCU
1
FOCA_ECO57
A:
[29-280]
---------------------------------------------------------------------------------------------------KH
P
L
K
T
F
Y
L
A
I
T
A
G
V
F
I
S
I
A
F
V
F
Y
I
T
A
T
TG
T
G
T
M
P
F
G
M
------
A
K
L
V
G
-
G
-
I
C
F
S
L
G
L
I
L
C
V
V
-
C
G
-------
A
D
L
F
TS-------
T
V
L
I
V
V
--
A
K
A
S
G
----
R
I
-----------
T
W
G
Q
-----
L
A
K
N
W
L
N
V
Y
F
G
N
L
V
G
-
A
L
L
F
----------------------
V
L
L
M
W
L
S
--
G
E
Y
--
M
TANG
Q
W
G
L
N
V
L
Q
T
A
D
H
K
V
H
H
T
F
I
------
E
A
---
V
C
L
G
I
--------------
L
A
N
L
M
V
C
L
A
V
W
M
S
Y
S
G
---
R
S
L
M
D
K
A
--
F
I
-
M
V
L
----------------------
P
V
A
M
F
V
A
S
G
F
E
H
S
I
--
A
N
M
F
------
M
I
P
M
G
I
V
-------
I
R
D
F
A
-
S
P
E
F
W
T
A
V
---
G
S
A
P
E
N
F
S
--
H
L
T
V
M
N
F
I
T
D
---
N
-
L
-
I
P
V
T
I
G
N
I
I
G
G
G
--
L
L
V
G
L
T
Y
W
V
I
Y
L
R
------------------------------
34
Fugue
50.87
25%
-
* C6 *
-
4QPR
-
KDPD_ECOLI
A:
[-3-652]
------------------------------------------------------------------------------------------------------------------------------------------------
D
L
Y
E
M
S
-
K
A
L
A
V
G
R
S
P
Q
D
I
-
A
A
-------
T
S
E
Q
---------
F
I
A
S
T
F
-----------
H
A
-----------
R
S
Q
V
-----
L
L
P
-------------------------------------------
D
D
N
--
G
K
L
--
Q
--------------------
P
L
T
------
H
P
QGM
T
P
W
D
------------------------------
D
---
A
I
A
Q
W
S
F
--
D
K
G
L
P
A
----------------------
G
A
G
T
------------------------
D
T
L
P
G
-------
V
P
Y
Q
I
-
L
P
L
K
S
G
E
K
---
T
Y
---
G
L
V
--
V
V
E
P
G
N
L
------
R
Q
L
M
I
P
E
Q
--
Q
R
L
L
E
T
--
F
T
L
L
V
A
N
A
L
E
R
L
T
K
L
A
A
A
L------------------------
32
Fugue
49.15
20%
-24
- C3 -
-
4NXT
1
MID51_HUMAN
A:
[9-345]
D
L
K
K
S
R
L
R
M
S
L
Q
E
K
L
L
T
Y
Y
R
N
RAAIP
A
G
E
Q
A
R
A
K
Q
A
A
V
D
I
C
A
E
L
R
S
F
L
R
A
KLPDMPL
R
D
M
Y
L
S
G
SLYDDLQVVTAD
H
I
Q
L
I
V
P
L
V
L
E
QNL
W
S
C
I
P
GEDTIMNVPG
F
F
L
V
R
R
E
NPEYFPRGSSYWDRCVV
G
G
Y
L
S
P
K
T
------
V
A
D
T
F
-
E
-
K
V
V
A
G
S
I
N
W
P
A
I
-
G
S
-------
L
L
D
Y
---------
V
I
R
P
A
P
--
P
P
E
A
L
----
T
L
-----------
E
V
Q
Y
-----
E
R
D
-----
K
H
L
F
I
D
F
-
L
P
S
V
----------------------
T
L
G
D
T
V
L
V
A
K
P
H
--
R
--------------------
L
A
Q
------
Y
D
---
N
L
W
R
L
S-------------
L
R
P
A
E
T
A
R
L
R
A
L
D
Q
A
D
SGC
R
S
L
C
L
K
I
--
L
K
-
A
I
C
----------------------
K
S
T
P
A
L
GHLT
A
S
Q
L
--
T
N
V
I
------
L
H
L
A
Q
E
E
ADWSPDM
L
A
D
R
F
-
L
Q
A
L
R
G
L
I
---
S
Y
L
E
A
G
V
L
--
P
S
A
L
N
P
K
V
N
L
F--
A
E
L
-
T
P
E
E
I
D
E
L
G
Y
T
L
--
Y
C
S
L
S
----
E
P
E
V
L
L----------------------------
31
Fugue
47.67
18%
34
- C6 -
-
5G51
-
?
A:
[1-157]
---------------------------------------------------------------------------------------------------------------------------------
E
E
Y
R
A
K
T
--------------------
G
Y
A
P
Y
Y
A
-
G
V
-------
W
H
S
F
---------
N
N
S
N
S
L
--
V
F
R
W
G
----
S
A
-----------
S
D
Q
I
A
Q
W
P
T
I
S
V
-----
P
R
G
E
L
A
F
-
L
R
I
K
-------------------------
D
G
K
Q
--
A
A
V
GT
Q
--------------------
P
W
R
------
T
M
---
V
V
W
P
S
--------------
G
H
G
----
Y
N
I
G
I
P
T
Y
N
-----------------------------------------
A
E
R
A
R
-----
Q
L
A
--
Q
H
L
Y
------
G
G
G
S
L
T
D
-------------
E
K
A
K
Q
L
F
V
---
P
A
N
Q
Q
G
P
G
--
K
V
S
N
G
N
P
V
W
E
---
V
M
R
-
A
P
L
A
T
Q
R
-------
A
H
I
Q
D
F
E
F
I
E
A
I
P
E
-----------------------------
33
Fugue
42.54
16%
-19
- C1 -
-
4WRT
-
?
C:
[9-258]
-----------------------------------------------------------------------------------------------------------------------------------
G
M
T
L
A
K
------
I
E
L
L
K
-
Q
-
L
L
R
D
N
E
A
K
T
V
L
K
Q
T
T
-------
V
D
Q
Y
---------
N
I
I
R
K
F
NT
S
R
I
E
K
----
N
P
-----------
S
L
R
M
-----
K
W
A
-----
M
C
S
N
F
P
L
-
A
L
T
K
G
D
M
A
N
R
IPLEYKGIQLKTNAED
I
G
T
K
G
Q
M
--
C
S
I
--
A
--------------------
A
V
T
------
W
W
---
N
T
Y
G
P
--------------
I
G
D
T
E
G
F
E
R
V
Y
E
S
F
F
L
---
R
K
M
R
L
D
N
--
A
T
-
W
G
R
I
T
F
G
P
V
E
R
V
RKRVLLNPLT
K
E
M
P
P
D
E
A
S
-----
N
V
I
--
M
E
I
L
FPKEAG
I
P
R
E
S
T
W
-------
I
H
R
E
L
-
I
K
E
K
R
E
K
L
KGT
M
I
T
P
I
V
L
A
--
Y
M
L
E
R
E
L
V
A
R
---
R
R
F
-
L
P
V
A
G
A
T
S
A
E
F
I
--
E
M
L
H
C
L
Q
G
E
N
W
R
Q
I
Y
H
P
G-------------------------
14
HHSearch
39.35
33%
-228
- C5 -
-
5L2R
1
?
A:
[433-459]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
-------
V
R
Q
Q
L
-
S
Q
Y
P
V
G
T
R
---
V
M
L
N
G
T
L
I
--
V
A
R
D
I
---------------------------------------------------------------------
2
PsiBlast_PDB
37.97
32%
-46
- C5 -
-
3QJJ
1
CAS6L_PYRHO
A:
[86-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
E
D
------
I
I
R
A
I
A
E
-------
A
V
E
K
S
-
P
E
F
K
I
G
E
L
---
S
F
L
V
G
D
I
K
--
A
I
K
V
K
E
L
G
K
E
N
V
F
S
T
L
-
S
P
I
V
V
R
T
V
K
F
E
G
--
N
K
L
R
--
H
W
-----------------------------------
17
HHSearch
37.90
16%
-307
- C5 -
-
3KLW
-
PRIB_BORPE
A:
[55-79]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
-------
L
A
L
L
L
-
A
D
T
P
L
G
T
E
---
M
Q
V
Q
G
F
L
A
--
P
A
------------------------------------------------------------------------
3
PsiBlast_PDB
37.41
32%
-25
- C5 -
-
3QJL
2
CAS6L_PYRHO
A:
[86-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
E
D
------
I
I
R
A
I
A
E
-------
A
V
E
K
S
-
P
E
F
K
I
G
E
L
---
S
F
L
V
G
D
I
K
--
A
I
K
V
K
E
L
G
K
E
N
V
F
S
T
L
-
S
P
I
V
V
R
T
V
K
F
E
G
--
N
K
L
R
--
H
W
-----------------------------------
6
HHSearch
36.21
36%
-139
- C- -
-
2ISB
-
?
A:
[10-37]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
-------
V
K
D
Q
I
-
L
K
L
K
V
G
D
V
---
V
Y
I
T
G
E
I
F
--
T
A
R
D
E
---------------------------------------------------------------------
26
HHSearch
35.62
18%
-306
- C5 -
-
3FHW
-
PRIB_BORPA
A:
[58-79]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
L
L
-
A
D
T
P
L
G
T
E
---
M
Q
V
Q
G
F
L
A
--
P
A
------------------------------------------------------------------------
1
PsiBlast_PDB
35.40
32%
-27
- C5 -
-
3QJP
1
CAS6L_PYRHO
A:
[85-150]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
E
D
------
I
I
R
A
I
A
E
-------
A
V
E
K
S
-
P
E
F
K
I
G
E
L
---
S
F
L
V
G
D
I
K
--
A
I
K
V
K
E
L
G
K
E
N
V
F
S
T
L
-
S
P
I
V
V
R
T
V
K
F
E
G
--
N
K
L
R
--
H
W
-----------------------------------
7
HHSearch
32.28
13%
-30
- C5 -
-
1WOC
-
PRIB_ECOLI
C:
[50-101]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
------
P
V
I
V
S
G
H
-------
E
N
Q
A
I
T
H
S
I
T
V
G
S
R
---
I
T
V
Q
G
F
I
S
--
C
H
K
A
K
N
G
----------------
L
-
S
K
M
V
--
L
H
A
E
Q
I
E
L
I
D
---------------------------------
4
PsiBlast_PDB
31.82
37%
-55
- C5 -
-
4JDZ
-
?
B:
[20-70]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
--
K
N
N
K
------
I
V
P
A
Q
D
Y
-------
L
A
L
K
--
S
Q
I
K
V
D
D
K
---
V
K
-
S
G
D
Y
F
--
T
I
K
Y
S
D
T
V
Q
V
---
Y
G
L
-
N
P
E
D
I
K
N
--------------------------------------------------
15
HHSearch
31.60
16%
-95
- C5 -
-
2FXQ
-
SSB_THEAQ
A:
[128-211]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
------
Q
V
---
I
L
M
G
N
--------------
L
T
R
D
P
D
L
R
Y
T
--
P
Q
G
T
---
A
V
V
R
L
G
L
--
A
V
-
N
E
R
-----------------------------------
R
--
T
H
F
L
------
E
V
Q
A
W
R
E
-------
L
A
E
W
A
-
S
E
L
R
K
G
D
G
---
L
L
V
I
G
R
L
V
N
D
S
W
T
S
S
S
G
-------------------------------------------------------------------
22
HHSearch
31.11
22%
-39
- C5 -
-
2VW9
-
SSB_HELPY
A:
[58-81]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-------
T
A
E
I
A
N
Q
Y
L
S
K
G
S
S
---
V
L
I
E
G
R
L
T
--
Y
-------------------------------------------------------------------------
10
HHSearch
31.04
15%
-164
* C5 *
-
3K8A
-
PRIB_NEIG1
A:
[49-82]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
E
I
------
P
A
R
I
L
G
R
-------
Q
A
E
E
W
-
Q
-
Y
R
Q
G
D
C
---
A
T
V
E
G
F
L
A
--
Q
K
S
-----------------------------------------------------------------------
8
HHSearch
30.96
13%
-38
- C5 -
-
1WOC
-
PRIB_ECOLI
D:
[50-100]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
------
P
V
I
V
S
G
H
-------
E
N
Q
A
I
T
H
S
I
T
V
G
S
R
---
I
T
V
Q
G
F
I
S
--
C
H
K
A
K
N
G
----------------
L
-
S
K
M
V
--
L
H
A
E
Q
I
E
L
I
----------------------------------